CN1548009A - Micro blood vessel anastomosing device - Google Patents
Micro blood vessel anastomosing device Download PDFInfo
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- CN1548009A CN1548009A CNA031122612A CN03112261A CN1548009A CN 1548009 A CN1548009 A CN 1548009A CN A031122612 A CNA031122612 A CN A031122612A CN 03112261 A CN03112261 A CN 03112261A CN 1548009 A CN1548009 A CN 1548009A
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Abstract
The micro blood vessel anastomosing device consists of one circular tube with outer diameter smaller than 6 mm and two hanging and connecting parts with raising height below 1 mm and set in the middle part of the circular tube. Or, it consists of one reducing tube comprising one fine circular tube of outer diameter below 6 mm, connecting tube and thick circular tube, and two hanging and connecting parts with raising height below 1 mm and set on the connecting tube. All the circular tube, the reducing tube and the hanging and connecting parts are made of titanium alloy. The break ends of two micro blood vessels are made to pass through the end of the circular tube or reducing tube and hung onto the hanging and connecting parts to complete the anastomosing operation.
Description
Technical field
The present invention relates to a kind of anastomosis apparatus, particularly relate to a kind of tiny blood vessels that makes and realize the tiny blood vessels anastomat that coincide.
Background technology
At present, though the identical method of tiny blood vessels with sewing for the most effective and commonly used, it still belongs to a kind of manipulation process, and its certain defective is arranged.During as operating cost, cause tube wall damage and anastomotic stricture easily, so that form thrombosis.Changing this manual operations, is the direction that the medical personnel makes great efforts.Since nineteen sixties, each state is all in the identical method of studying the other tiny blood vessels, as apparatus method, laser method, Method for bonding etc.But these methods are also at the experimental stage at present for the tiny blood vessels of external diameter less than 6 millimeters, and patency rate is desirable not enough, and no clinical value is still needed and continued research.The applicant is through carrying out market survey and literature retrieval to the tiny blood vessels anastomosis with apparatus, finds to obtain clinically the technical scheme of applying as yet.
Summary of the invention
The objective of the invention is to overcome the shortcoming of above-mentioned prior art, the tiny blood vessels anastomat that provide a kind of and easy to operately save time, patency rate is high.
For achieving the above object, the invention provides a kind of tiny blood vessels anastomat, it be by external diameter less than 6 millimeters pipe, be located on the outer wall of pipe middle part and height of projection constitutes less than 1 millimeter two hanging parts.
Described each hanging part constitutes by being distributed in horizontal protruding pins on the circular tube external wall, more than 2, and the maximum radial distance between protruding pin and the circular tube external wall is less than 1 millimeter, and the protruding pin needle point in any hanging part is towards another hanging part.
The material of described pipe, protruding pin is a titanium alloy.
For achieving the above object, the present invention also provides a kind of tiny blood vessels anastomat, it is to be made of reducer pipe, two hanging parts, reducer pipe is communicated with successively less than 6 millimeters mini diameter tube, connection tube, thick pipe by external diameter and forms, two hanging parts be located on the outer wall of connection tube and height of projection less than 1 millimeter.
Described each hanging part constitutes by being distributed in horizontal protruding pins on the connection tube outer wall, more than 2, and the maximum radial distance between protruding pin and the connection tube outer wall is less than 1 millimeter, and the protruding pin needle point in any hanging part is towards another hanging part.
The material of described reducer pipe, protruding pin is a titanium alloy.
Adopt after the above structure, because this tiny blood vessels anastomat is by the pipe of external diameter less than 6 millimeters, be located on the outer wall of pipe middle part and height of projection constitutes less than 1 millimeter two hanging parts, or by the reducer pipe of external diameter less than 6 millimeters, be located on (the being connection tube) outer wall of reducer pipe middle part and height of projection constitutes less than 1 millimeter two hanging parts, therefore when this anastomat uses in the operating process of identical tiny blood vessels, after the two ends that operator allow the broken ends of fractured bone of two tiny blood vessels pass pipe or reducer pipe are respectively also overlapped securely and are hung on two hanging parts, just can finish anastomosis operation convenient and time-savingly, and the patency rate height.So the present invention have easy to operately save time, advantage that patency rate is high, be worth applying clinically.
Description of drawings
Fig. 1 is the half sectional view of first embodiment of the invention;
Fig. 2 is the A-A cutaway view of Fig. 1;
Fig. 3 is the full sectional view of second embodiment of the invention;
Fig. 4 is the B-B cutaway view of Fig. 3;
Fig. 5 is the C-C cutaway view of Fig. 3.
The specific embodiment
Below in conjunction with accompanying drawing two embodiments of the present invention are specifically described:
First embodiment
Referring to Fig. 1, Fig. 2: this tiny blood vessels anastomat is to be equaled 5 millimeters pipe 1 by external diameter, two hanging parts of being located on the pipe 1 middle part outer wall constitute, described each hanging part is made of four horizontal protruding pins 2 that are distributed on pipe 1 outer wall, maximum radial distance between protruding pin 2 and pipe 1 outer wall equals 0.5 millimeter (height of projection that is hanging part equals 0.5 millimeter), the needle point of any hanging part convexity pin 2 is towards another hanging part, and the needle point of two hanging part convexity pins 2 each other one by one over against, described pipe 1, the material of protruding pin 2 is the titanium alloy with good biocompatibility, like this, this tiny blood vessels anastomat is non-stimulated to vascular tissue, no foreign body reaction can be positioned in the body muchly.The length of pipe 1 is 2.6cm, the wall thickness of pipe 1 is 0.3mm, axial distance between the homonymy termination of the stiff end of protruding pin 2 and pipe 1 is 0.8mm, and the diameter of protruding pin 2 is 0.3mm, and the horizontal-extending length of protruding pin 2 (being the tip of protruding pin 2 and the axial distance between the stiff end) is 3mm.
This tiny blood vessels anastomat can be made into series of products: the external diameter of pipe 1 also can be divided into other 11 specifications: 1.0,1.2,1.5,1.8,2,2.3,2.5,2.8,3,3.5 and 4mm.The length of pipe 1 is 2～4cm, and the wall thickness of pipe 1 is 0.2～0.4mm.Maximum radial distance between protruding pin 2 and pipe 1 outer wall is less than 1mm, and the axial distance between the homonymy termination of the stiff end of protruding pin 2 and pipe 1 is 0.8～1.2mm, and the diameter of protruding pin 2 is 0.1～0.3mm, and the horizontal-extending length of protruding pin 2 is 2～5mm.
The identical method of this tiny blood vessels anastomat:
One, according to supplying, being distinguished the blood vessel diameter size, selects the anastomat of corresponding caliber.
Two, the broken ends of fractured bone of finishing anastomosis of blood vessel, and soft blood vessel dilating bore.
Three, with transplanted tissue in place and adjust for the district blood vessel direction, angle, make its distortionless, no tension force, again pipe 1 one ends are stretched in the tube chamber for district's blood vessel, and allow the protruding pin 2 of homonymy pass blood vessel wall from inside to outside at distance ends of vessels 3～6mm place, the blood vessel of pulling back again makes blood vessel wall hanging jail on the stiff end of protruding pin 2.
Four, pipe 1 other end is stretched in the tube chamber of being distinguished blood vessel, and allow the protruding pin 2 of homonymy pass blood vessel wall from inside to outside at distance ends of vessels 3～6mm place, the blood vessel of pulling back again makes blood vessel wall hanging jail on the stiff end of protruding pin 2.
Five, will dock each other at the middle part of pipe 1 for, the broken ends of fractured bone of being distinguished blood vessel, and protruding pin 2 arrangements of both sides are smooth-going, and after checking vascular patency, in the soft tissue around again anastomotic stoma being embedded in, end of operation coincide.
The applicant uses this tiny blood vessels anastomat that titanium alloy makes and has carried out the tiny blood vessels experimentation of coincideing.Experiment is carried out on Canis familiaris L. and rabbit body, adopts the femoral artery of Canis familiaris L., the arterial anastomosis that brachial artery is made 2～3mm, adopts the femoral artery of rabbit, the vascular anastomosis that vein is made 1.5～1.8mm, and the experiment grouping sees Table 1:
Table 1 tiny blood vessels anastomat method is coincide and is tested grouping
| Grouping | Arteriovenous | Blood vessel external diameter (mm) | Blood vessel number (root) | Laboratory animal |
| ????A | Tremulous pulse | ????2.7～3.0 | ????10 | Canis familiaris L. |
| ????B | Tremulous pulse | ????2.0～2.3 | ????10 | Canis familiaris L. |
| ????C | Tremulous pulse | ????1.5～1.8 | ????10 | Rabbit |
| ????D | Vein | ????1.5～1.8 | ????10 | Rabbit |
Carry out the experiment that tiny blood vessels anastomat method is coincide with regard to above four groups, it is as follows to obtain a result:
(1) unobstructed situation
1. promptly checked in 15 minutes behind this unobstructed inspection anastomosis of blood vessel, see after all vascular anastomosiss all unobstructed.
2. unobstructed inspection at a specified future date:
The A group: 2.7～3mm tremulous pulse, all unobstructed good, patency rate is 100%.
The B group: 2.0～2.3mm tremulous pulse, all unobstructed good, patency rate is 100%.
The C group: 1.5～1.8mm tremulous pulse, all unobstructed good, patency rate is 100%.
D group: 1.5～1.8mm vein, in 10 9 unobstructed good, 1 blocking barrier.Patency rate is 90%.
(2) pathological examination has found that theca interna and endotheliocyte cover anastomotic stoma in the back seven days specimen of coincideing.In 100 days specimen, the blood vessel wall of anastomotic stoma is smooth, and endotheliocyte covers complete.The thickness of anastomotic stoma place inner membrance and middle film is not seen obviously in most of specimen and is thickened, and the middle film around pipe is not seen tangible foreign body reaction.
The scanning electron microscope inspection can be seen in 1 day specimen in the crack of anastomotic stoma has fibrin to adhere to, and the endothelial cell form of anastomotic stoma both sides is normal.The endotheliocyte that can see the anastomotic stoma both sides in 3 days, 7 days specimen has begun growth, and begins to fill and lead up the depression at anastomotic stoma place.Can see the depression of anastomotic stoma and be filled and led up in 15 days specimen, endotheliocyte is at anastomotic stoma place well-grown.See that vascular anastomosis is smooth in the specimen of 30 days and 45 days, the depression at anastomotic stoma place is beyond recognition.
(3) vascular anastomosis time this tiny blood vessels anastomat method is coincide the time, and the shortest is 4 minutes and 22 seconds, and the longest is 7 minutes and 34 seconds, average out to 5 minutes and 11 seconds.
Conclusion is according to the test of this group, and the applicant thinks that titanium alloy tiny blood vessels anastomat is in light weight, the intensity height, and tissue reaction is little in human body.The tiny blood vessels anastomat method of coincideing has easy to operate, and the time that coincide is short, is applicable to the arterial anastomosis of 1.5～5mm external diameter, can reach 100% patency rate, in the venous anastomosis of 1.5～1.8mm, still can obtain 90% patency rate.This experiment provides more valuable foundation for clinical practice, is worth applying clinically.
Second embodiment
Referring to Fig. 3-Fig. 5: this tiny blood vessels anastomat is by reducer pipe, two hanging parts constitute, reducer pipe is by mini diameter tube 1, connection tube 2, thick pipe 3 is communicated with successively and forms, two hanging parts are located on the outer wall of connection tube 2, described each hanging part is made of four horizontal protruding pins 4 that are distributed on connection tube 2 outer walls, maximum radial distance between protruding pin 4 in left side and connection tube 2 outer walls equals 0.8 millimeter (promptly the height of projection of this hanging part equals 0.8 millimeter), maximum radial distance between protruding pin 4 in right side and connection tube 2 outer walls equals 0.5 millimeter (promptly the height of projection of this hanging part equals 0.5 millimeter), the needle point of any hanging part convexity pin 4 is towards another hanging part, and the needle point of two hanging part convexity pins 4 each other one by one over against, described reducer pipe, the material of protruding pin 4 is the titanium alloy with good biocompatibility, like this, this tiny blood vessels anastomat is non-stimulated to vascular tissue, no foreign body reaction can be positioned in the body muchly.The length of reducer pipe is 2.6cm, the wall thickness of reducer pipe is 0.3mm, the external diameter of mini diameter tube 1, thick pipe 3 is respectively 3mm, 5mm, connection tube 2 for uncovered little, the uncovered big round table-like cylindrical shell of right-hand member of left end and about it end external diameter be respectively 3mm, 5mm, axial distance between the homonymy termination of the stiff end of protruding pin 4 and reducer pipe is 0.8mm, the diameter of protruding pin 4 is 0.3mm, and the horizontal-extending length of protruding pin 4 (being the tip of protruding pin 4 and the axial distance between the stiff end) is 3mm.
This tiny blood vessels anastomat can be made into series of products: the external diameter of mini diameter tube 1 also can be divided into other eight specifications: 1.0,1.2,1.5,1.8,2,2.3,2.5 and 2.8mm.The external diameter of thick pipe 3 also can be divided into other seven specifications: 2,2.3,2.5,2.8,3,3.5 and 4mm.The length of reducer pipe is 2～4cm, and the wall thickness of reducer pipe is at 0.2～0.4mm.Maximum radial distance between protruding pin 4 and connection tube 2 outer walls is less than 1mm, and the axial distance between the homonymy termination of the stiff end of protruding pin 4 and reducer pipe is 0.8～1.2mm, and the diameter of protruding pin 4 is 0.1～0.3mm, and the horizontal-extending length of protruding pin 4 is 2～5mm.
The identical method of present embodiment no longer repeats here with first embodiment.
The applicant has also carried out the identical experimentation of tiny blood vessels to present embodiment, and experimentation is identical substantially with first embodiment.Experiment conclusion shows: present embodiment has easy to operate, and the time that coincide is short, the advantage that patency rate is high.
Above-described only is preferred implementation of the present invention.Should be pointed out that for the person of ordinary skill of the art under the prerequisite that does not break away from the principle of the invention, can also make some modification and improvement, these also should be considered as belonging to protection scope of the present invention.Such as: pipe, mini diameter tube, the external diameter of thick pipe and the number of protruding pin can determine flexibly as required that also the protruding pin number in two hanging parts also can be different; The needle point of the two hanging part convexity pins certain angle that also can stagger each other, and the protruding pin in the hanging part may also extend between the protruding pin in another hanging part; Each hanging part also can upwarp that shape tilts protruding pin, the sharp keen projection (as hook) that upwarps the protruding pin of shape circular arc or other shape constitutes by a plurality of.
The present invention also can be used for the anastomosis operation of tube chambers such as deferent duct, fallopian tube, ureter, ductus choledochus except that being used for tiny blood vessels coincide, and the scope of application is wider.
Claims (6)
1, tiny blood vessels anastomat is characterized in that: it be by external diameter less than 6 millimeters pipe, be located on the outer wall of pipe middle part and height of projection constitutes less than 1 millimeter two hanging parts.
2, tiny blood vessels anastomat according to claim 1, it is characterized in that: each hanging part constitutes by being distributed in horizontal protruding pins on the circular tube external wall, more than 2, maximum radial distance between protruding pin and the circular tube external wall is less than 1 millimeter, and the protruding pin needle point in any hanging part is towards another hanging part.
3, tiny blood vessels anastomat according to claim 1 and 2 is characterized in that: the material of pipe, protruding pin is a titanium alloy.
4, tiny blood vessels anastomat, it is characterized in that: it is to be made of reducer pipe, two hanging parts, reducer pipe is communicated with successively less than 6 millimeters mini diameter tube, connection tube, thick pipe by external diameter and forms, two hanging parts be located on the outer wall of connection tube and height of projection less than 1 millimeter.
5, tiny blood vessels anastomat according to claim 4, it is characterized in that: each hanging part constitutes by being distributed in horizontal protruding pins on the connection tube outer wall, more than 2, maximum radial distance between protruding pin and the connection tube outer wall is less than 1 millimeter, and the protruding pin needle point in any hanging part is towards another hanging part.
6, according to claim 4 or 5 described tiny blood vessels anastomats, it is characterized in that: the material of reducer pipe, protruding pin is a titanium alloy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031122612A CN1548009A (en) | 2003-05-22 | 2003-05-22 | Micro blood vessel anastomosing device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031122612A CN1548009A (en) | 2003-05-22 | 2003-05-22 | Micro blood vessel anastomosing device |
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| CN1548009A true CN1548009A (en) | 2004-11-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA031122612A Pending CN1548009A (en) | 2003-05-22 | 2003-05-22 | Micro blood vessel anastomosing device |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110236621A (en) * | 2018-03-09 | 2019-09-17 | 北京大学人民医院 | Neural casing for the suture of neural transpositional repair |
| CN110236622A (en) * | 2018-03-09 | 2019-09-17 | 北京大学人民医院 | Artificial nerve catheter and preparation method thereof for the suture of different size bridge grafting nerves |
| CN112294381A (en) * | 2020-10-27 | 2021-02-02 | 中南大学湘雅医院 | Sleeve device for microsurgery blood vessel and lymphatic vessel anastomosis |
-
2003
- 2003-05-22 CN CNA031122612A patent/CN1548009A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110236621A (en) * | 2018-03-09 | 2019-09-17 | 北京大学人民医院 | Neural casing for the suture of neural transpositional repair |
| CN110236622A (en) * | 2018-03-09 | 2019-09-17 | 北京大学人民医院 | Artificial nerve catheter and preparation method thereof for the suture of different size bridge grafting nerves |
| CN110236621B (en) * | 2018-03-09 | 2024-03-01 | 北京大学人民医院 | Nerve sleeve for nerve transposition repair suture |
| CN112294381A (en) * | 2020-10-27 | 2021-02-02 | 中南大学湘雅医院 | Sleeve device for microsurgery blood vessel and lymphatic vessel anastomosis |
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