CN1504212A - Medicine for nourishing yin and fortifying kidney, benefiting qi and fortifying spleen , and its preparation method - Google Patents
Medicine for nourishing yin and fortifying kidney, benefiting qi and fortifying spleen , and its preparation method Download PDFInfo
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- CN1504212A CN1504212A CNA021446962A CN02144696A CN1504212A CN 1504212 A CN1504212 A CN 1504212A CN A021446962 A CNA021446962 A CN A021446962A CN 02144696 A CN02144696 A CN 02144696A CN 1504212 A CN1504212 A CN 1504212A
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Abstract
The invention discloses a medicament for reinforcing body fluid, nourishing blood, and enlivening the spleen, which is prepared from the raw materials of wolfberry fruit, prepared rehmannia root, tortoise shell, ginseng, white atractylodes rhizome, haw, hairy deerhorn, epimeddium, morinda root achyranthes and cyathula root, and the preparation process includes, extracting by different solvents, purifying, and concentration. The advantages of the medicine is safety, effectiveness, and easiness in application.
Description
Technical field
The present invention relates to Chinese herbal medicine and preparation method thereof, the preparation method of specifically a kind of enriching yin and nourishing kidney, replenishing QI to invigorate the spleen medicine and this medicine.
Background technology
Human growth, growth, aging and all diseases and spleen, kidney are closely related, and the people is to person in middle and old age, often occur due to the asthenia of both the spleen and kidney soreness of the waist and knees, fatigue and weak, have a dizzy spell, disease such as deafness and tinnitus.
To the treatment of primary disease, following clinical difficult problem puzzlement is arranged at present:
The common kidney-reinforcing drug of existing market is just emphasized kidney-replenishing simply, its result, though certain curative effect is arranged, great majority are hot dry product, have grown service time to make the high Sheng of yang-energy, and cloudy Tianjin is impaired, and constipation yellowish urine, nose dental hemorrhage etc. dry mouth and parching tongue appears, in showing tremendous enthusiasm interior giving birth to.
Summary of the invention
The object of the present invention is to provide a kind ofly can comprehensively improve soreness of the waist and knees, fatigue and weak, have a dizzy spell, symptom such as deafness and tinnitus, and have the immunity of organisms of promotion function and improve, and alleviate showing tremendous enthusiasm in the medicine of ill symptomses such as life, dry mouth and tougue.
Another object of the present invention provides the formulation method of these enriching yin and nourishing kidney, replenishing QI to invigorate the spleen medicine.
Solution of the present invention be based on motherland's medical science to soreness of the waist and knees, fatigue and weak, have a dizzy spell, the understanding and the Therapeutic Principle of disease mechanism such as deafness and tinnitus, form with reference to modern medicinal agents, pharmaceutical research achievement.
Medicine of the present invention is to make (consumption is a weight portion) by following component:
1～15 part of 5～20 parts of Carapax Et Plastrum Testudinis of 5～30 parts of Radix Rehmanniae Preparata of Fructus Lycii
5～20 parts of 5～10 portions of Fructus Crataegis of 1～15 part of Rhizoma Atractylodis Macrocephalae of Radix Ginseng
1～15 part of 5～20 parts of Radix Morindae Officinalis of 1～15 part of Herba Epimedii of Cornu Cervi Pantotrichum
1～15 part of Radix Achyranthis Bidentatae
The formula optimization weight proportion scope of preparation medicine of the present invention is:
2～13 parts of 5～15 parts of Carapax Et Plastrum Testudiniss of 5～25 parts of Radix Rehmanniae Preparata of Fructus Lycii
5～15 parts of 5～15 portions of Fructus Crataegis of 2～13 parts of Rhizoma Atractylodis Macrocephalaes of Radix Ginseng
2～13 parts of 5～15 parts of Radix Morindae Officinaliss of 2～13 parts of Herba Epimedii of Cornu Cervi Pantotrichum
2～13 parts of Radix Achyranthis Bidentataes
Above-mentioned each component is made medicine production method of the present invention is:
1. Radix Ginseng, Fructus Crataegi, Cornu Cervi Pantotrichum add alcohol reflux, filter, and merging filtrate reclaims ethanol, and filtrate and medicinal residues are standby.
2. get Carapax Et Plastrum Testudinis in addition, decoct with water, filter, filtrate and medicinal residues are standby.
3. after Fructus Lycii, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Herba Epimedii, Radix Morindae Officinalis, Radix Achyranthis Bidentatae being added above-mentioned medicinal residues, decoct with water, merging filtrate concentrates, and adds ethanol, and precipitate with ethanol filters, and reclaims ethanol.
4. above-mentioned three kinds of filtrates merge, and make mixture.
An important feature of medicine of the present invention is:
1. press the Chinese medical theory prescription, and the pure Chinese medicinal preparation of making in conjunction with the modern scientific research achievement.
The prescription Chinese crude drug through science extract, purification, improve active constituent content, reduce dose, confirm evident in efficacyly through pharmacodynamics, toxicological experiment, do not see toxicity.Reached purpose safe, effective, taking convenience.
3. medicine of the present invention provides a kind of new medicine, has increased a kind of strong weapon for clinical with the card medication.
The clinical use result of medicine of the present invention shows that following advantage is arranged:
1. to select natural plant for use be raw material in the present invention, presses the comprehensive function treatment asthenia of both the spleen and kidney of Chinese medical theory prescription.
2. medicine of the present invention through extract, purification, active constituent content height, dose are little, and the strict quality index is arranged, and reach safe and effective, and be quality controllable, the taking convenience requirement.Meet national medical rules.
3. the medicine that provides of the present invention can be taken for a long time, can not occur the high Sheng of yang-energy, cloudy Tianjin impaired, showing tremendous enthusiasm in untoward reaction such as life, dry mouth and parching tongue, constipation yellowish urine, nose dental hemorrhage.
For showing the effect of Drug therapy asthenia of both the spleen and kidney of the present invention, medicine of the present invention is through the clinical observation of 100 routine systems, according to " new Chinese medicine clinical research guideline " version in 1993 draft in, the asthenia of both the spleen and kidney patient that confirms of Western medicine diagnose, dialectical standard.
Differential diagnosis in tcm standard asthenia of both the spleen and kidney card
Instructions of taking: medicine of the present invention each 1 time sooner or later, each 10ml is a course of treatment all around.
Result of the test
Efficacy assessment standard
1. produce effects asthenia of both the spleen and kidney symptom is obviously improved.
2. effectively the asthenia of both the spleen and kidney symptom makes moderate progress.
3. invalidly do not reach above-mentioned standard person.
Efficacy analysis: the detailed impression of this clinical observation, see the following table general curative effect for details
The curative effect summary table
Produce effects enabledisable effective percentage
The example number
N ％ N ％ N ％ ％
100 39 39 51 51 10 10 90
The clinical efficacy total effective rate of medicine of the present invention is 90%, and obvious effective rate is 39%.
The specific embodiment
Embodiment 1
Take by weighing raw material by following proportioning
Fructus Lycii 20kg Radix Rehmanniae Preparata 10kg Carapax Et Plastrum Testudinis 5kg
Radix Ginseng 5kg Rhizoma Atractylodis Macrocephalae 10kg Fructus Crataegi 10kg
Cornu Cervi Pantotrichum 5kg Herba Epimedii 10kg Radix Morindae Officinalis 5kg
Radix Achyranthis Bidentatae 5kg
Embodiment 2
Take by weighing raw material by following proportioning
Fructus Lycii 5kg Radix Rehmanniae Preparata 5kg Carapax Et Plastrum Testudinis 1kg
Radix Ginseng 1kg Rhizoma Atractylodis Macrocephalae 5kg Fructus Crataegi 5kg
Cornu Cervi Pantotrichum 1kg Herba Epimedii 5kg Radix Morindae Officinalis 1kg
Radix Achyranthis Bidentatae 1kg
Embodiment 3
Take by weighing raw material by following proportioning
Fructus Lycii 30kg Radix Rehmanniae Preparata 20kg Carapax Et Plastrum Testudinis 15kg
Radix Ginseng 15kg Rhizoma Atractylodis Macrocephalae 20kg Fructus Crataegi 20kg
Cornu Cervi Pantotrichum 15kg Herba Epimedii 20kg Radix Morindae Officinalis 15kg
Radix Achyranthis Bidentatae 15kg
Embodiment 4
Take by weighing raw material by following proportioning
Fructus Lycii 5kg Radix Rehmanniae Preparata 5kg Carapax Et Plastrum Testudinis 2kg
Radix Ginseng 2kg Rhizoma Atractylodis Macrocephalae 5kg Fructus Crataegi 2kg
Cornu Cervi Pantotrichum 2kg Herba Epimedii 5kg Radix Morindae Officinalis 2kg
Radix Achyranthis Bidentatae 2kg
Embodiment 5
Take by weighing raw material by following proportioning
Fructus Lycii 25kg Radix Rehmanniae Preparata 15kg Carapax Et Plastrum Testudinis 13kg
Radix Ginseng 13kg Rhizoma Atractylodis Macrocephalae 15kg Fructus Crataegi 15kg
Cornu Cervi Pantotrichum 13kg Herba Epimedii 15kg Radix Morindae Officinalis 13kg
Radix Achyranthis Bidentatae 13kg
Preparation method is as follows:
More than ten flavors, get Radix Ginseng, Fructus Crataegi, Cornu Cervi Pantotrichum and add 8 times of amounts of 75% ethanol, reflux, extract, 2 hours adds 5 times of amounts of 50% ethanol again, reflux, extract, 1.5 hours filters, and merging filtrate reclaims ethanol, to relative density 1.10～1.15 (50～60 ℃), placed 12 hours, filter, filtrate and medicinal residues are standby.Other gets Carapax Et Plastrum Testudinis, adds 8 times of amounts of water and soaks 4 hours earlier, decocts 4 hours again, filters, and filtrate and medicinal residues are standby.After all the other Six-elements are added above-mentioned medicinal residues, decoct with water secondary, add 8 times of amounts of water for the first time and decocted 2 hours, add for the second time 6 times of amounts of water and decocted 1 hour, filter merging filtrate, be concentrated into relative density 1.12～1.15 (50～60 ℃), add ethanol, make that to contain alcohol amount be 75%, placed 24 hours, filter, reclaim ethanol, to relative density 1.10～1.15 (50～60 ℃), filtrate for later use.Above-mentioned three kinds of filtrates are merged, add Mel 200g, steviosin 3g, sorbic acid 1g, thin up filters to 1000ml, packing, and sterilization, promptly.
The present invention can be made into the arbitrary dosage form on the pharmaceuticss such as mixture, syrup, granule, tablet, medicated wine, pill, injection.
Claims (5)
1. the medicine of enriching yin and nourishing kidney, replenishing QI to invigorate the spleen is characterized in that it is to be made by the following weight proportion raw material:
1～15 part of 5～20 parts of Carapax Et Plastrum Testudinis of 5～30 parts of Radix Rehmanniae Preparata of Fructus Lycii
5～20 parts of 5～10 portions of Fructus Crataegis of 1～15 part of Rhizoma Atractylodis Macrocephalae of Radix Ginseng
1～15 part of 5～20 parts of Radix Morindae Officinalis of 1～15 part of Herba Epimedii of Cornu Cervi Pantotrichum
1～15 part of Radix Achyranthis Bidentatae.
2. the medicine of enriching yin and nourishing kidney according to claim 1, replenishing QI to invigorate the spleen is characterized in that wherein each raw material weight proportioning is:
2～13 parts of 5～15 parts of Carapax Et Plastrum Testudiniss of 5～25 parts of Radix Rehmanniae Preparata of Fructus Lycii
5～15 parts of 5～15 portions of Fructus Crataegis of 2～13 parts of Rhizoma Atractylodis Macrocephalaes of Radix Ginseng
2～13 parts of 5～15 parts of Radix Morindae Officinaliss of 2～13 parts of Herba Epimedii of Cornu Cervi Pantotrichum
2～13 parts of Radix Achyranthis Bidentataes.
3. the medicine of enriching yin and nourishing kidney according to claim 1, replenishing QI to invigorate the spleen is characterized in that wherein each raw material weight proportioning is:
5 parts of 10 parts of Carapax Et Plastrum Testudiniss of 20 parts of Radix Rehmanniae Preparata of Fructus Lycii
10 parts of 10 portions of Fructus Crataegis of 5 parts of Rhizoma Atractylodis Macrocephalaes of Radix Ginseng
5 parts of 10 parts of Radix Morindae Officinaliss of 5 parts of Herba Epimedii of Cornu Cervi Pantotrichum
5 parts of Radix Achyranthis Bidentataes.
4. the medicine of enriching yin and nourishing kidney according to claim 1, replenishing QI to invigorate the spleen is characterized in that said medicine can be made into the arbitrary dosage form on the pharmaceuticss such as mixture, syrup, granule, tablet, medicated wine, pill, injection.
5. the process for preparing medicine of enriching yin and nourishing kidney, replenishing QI to invigorate the spleen is characterized in that getting Radix Ginseng, Fructus Crataegi, Cornu Cervi Pantotrichum and adds alcohol reflux, filters, and merging filtrate reclaims ethanol, and filtrate and medicinal residues are standby; Other gets Carapax Et Plastrum Testudinis, decocts with water, and filters, and filtrate and medicinal residues are standby, Fructus Lycii, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Herba Epimedii, Radix Morindae Officinalis, Radix Achyranthis Bidentatae are added above-mentioned medicinal residues after, decoct with water, merging filtrate concentrates, and adds ethanol, precipitate with ethanol, filter, reclaim ethanol, above-mentioned three kinds of filtrates merge, and make.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021446962A CN1199679C (en) | 2002-12-05 | 2002-12-05 | Medicine for nourishing yin and fortifying kidney, benefiting qi and fortifying spleen , and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB021446962A CN1199679C (en) | 2002-12-05 | 2002-12-05 | Medicine for nourishing yin and fortifying kidney, benefiting qi and fortifying spleen , and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1504212A true CN1504212A (en) | 2004-06-16 |
| CN1199679C CN1199679C (en) | 2005-05-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB021446962A Expired - Fee Related CN1199679C (en) | 2002-12-05 | 2002-12-05 | Medicine for nourishing yin and fortifying kidney, benefiting qi and fortifying spleen , and its preparation method |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100388925C (en) * | 2005-06-02 | 2008-05-21 | 成都中医药大学 | Medication composition of replenishing qi to invigorate the spleen, preparation method and usage |
| CN102586066A (en) * | 2012-03-14 | 2012-07-18 | 济南宏济堂制药有限责任公司 | Health-care wine and preparation method thereof |
| CN103160415A (en) * | 2013-03-07 | 2013-06-19 | 王玉兰 | Tortoise shell cassia tora wine |
| CN104398688A (en) * | 2014-12-10 | 2015-03-11 | 无锡瑞年实业有限公司 | Traditional Chinese medicine oral liquid for increasing immunity |
| CN104435432A (en) * | 2014-12-10 | 2015-03-25 | 无锡瑞年实业有限公司 | Composition for reinforcing immunity |
-
2002
- 2002-12-05 CN CNB021446962A patent/CN1199679C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100388925C (en) * | 2005-06-02 | 2008-05-21 | 成都中医药大学 | Medication composition of replenishing qi to invigorate the spleen, preparation method and usage |
| CN102586066A (en) * | 2012-03-14 | 2012-07-18 | 济南宏济堂制药有限责任公司 | Health-care wine and preparation method thereof |
| CN103160415A (en) * | 2013-03-07 | 2013-06-19 | 王玉兰 | Tortoise shell cassia tora wine |
| CN104398688A (en) * | 2014-12-10 | 2015-03-11 | 无锡瑞年实业有限公司 | Traditional Chinese medicine oral liquid for increasing immunity |
| CN104435432A (en) * | 2014-12-10 | 2015-03-25 | 无锡瑞年实业有限公司 | Composition for reinforcing immunity |
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| Publication number | Publication date |
|---|---|
| CN1199679C (en) | 2005-05-04 |
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