CN1425386A - Dimethyl-sulfone sulfide supplementary agent and its overlapped health articles - Google Patents

Dimethyl-sulfone sulfide supplementary agent and its overlapped health articles Download PDF

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Publication number
CN1425386A
CN1425386A CN02158855A CN02158855A CN1425386A CN 1425386 A CN1425386 A CN 1425386A CN 02158855 A CN02158855 A CN 02158855A CN 02158855 A CN02158855 A CN 02158855A CN 1425386 A CN1425386 A CN 1425386A
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China
Prior art keywords
vitamin
dimethyl sulfone
chitosan
dimethyl
sulfate
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Pending
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CN02158855A
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Chinese (zh)
Inventor
张勇
王红
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XINDIE CHITIN CO Ltd DALIAN
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XINDIE CHITIN CO Ltd DALIAN
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Priority to CN02158855A priority Critical patent/CN1425386A/en
Publication of CN1425386A publication Critical patent/CN1425386A/en
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Abstract

The present invention relates to health food and sulfur supplementing preparation and health food with dimethyl sulfone sulfide as main material. The present invention features that dimethyl sulfone sulfide is compounded with vitamin A, vitamin C, vitamin E, glucosamine hydrochloride, glucosamine sulfate, chitosan oligose, marine biological product, etc. into serial health products, which may be used as sulfur supplementing preparation and health food for delaying senility, beautifying, antifatigue, regulating hyperosteogency and rheumatic arthritis, etc.

Description

Dimethyl sulfone sulfur supplement and stack health product thereof
Technical field
The invention belongs to the health food field, relating to the dimethyl sulfone is sulfur supplement and the synergetic health food thereof that raw material is made.
Background technology
As the cell of human body basic composition unit, become all organs of human body, tissue by about 100,000,000,000,000 groups of cells, 7/10ths cell senescence aging is arranged every day approximately, normal fully as metabolism, every day, regenerative cell should have corresponding quantity.With age, regenerative cell can not reach the quantity of senile cell, and old and feeble cell impels each organ and organizes also and wear out gradually, and this is the natural law.
If can make metabolism cell senescence be delayed than balance, just possible slow down aging reduces the various diseases symptom.And prevent oxygen-derived free radicals poisonous effect in the human body, and must be by antioxidant radical---Reducing agent is eliminated.The free agent of antioxygen is a mammal life-span factor of determination, the level of antioxidant and human longevity have the positive correlation of height in the body, with advancing age, human body can not meet the demands far away because of the antioxidant that has, must replenish from the external world, to remove the poisonous effect of oxygen-derived free radicals to greatest extent, antioxidant is slow down aging, prophylactic moderator.
When superoxide radical acts on insatiable hunger and closes fatty acid, can generate lipid oxide, cause that cell flexibility and permeability descend, nutrition and refuse can't fully exchange, and pigmentation, skin-color split, produce wrinkle.
Dimethyl sulfone is the main source of sulfur in the organ-tissues such as sulfur-containing amino acid, glutathion antioxidant, collagen, albumen, insulin, skin, cartilage, connection liquid, hair, fingernail, tooth, skeleton, muscle, tendon such as cystine in the human body.Dimethyl sulfone exists in biology.In the mankind's such as fish, marine product, fowl, meat, egg, milk, fruit, vegetable, tea, coffee F﹠B, all have a great deal of.The LD of dimethyl sulfone 50Therefore>20g/Kg, can think innocuous substance.
Food provides people required dimethyl sulfone, but because dimethyl sulfone is volatile, food (is fried in shallow oil in storing and hot-working, boil, fry, steam etc.) process, the dimethyl sulfone loss is serious, some crowd can't obtain enough dimethyl sulfones from food and supply sulphur compound with other, make the aminoacid of sulfur-bearing, peptide, albumen, the collagen deficiency, thus aging caused, tired, alopecia, fingernail has slight crack, irritated, asthma, arthritis, gastrointestinal has inflammation, wound is difficult to healing, constipation, diarrhoea, hypomnesis, immunity degradation, produce different pathological changes such as acne and canceration.
Many researchs are pointed out compound prescription with dimethyl sulfone and other material at different crowd.Propose MSM+Vc+ β-1.3-glucosan as U.S.5753696 and can improve human body dehydrogenation table hero (steroid) ketone, increase body immunity.WO 01/01976 proposes effective to arthritis by active PCE+MSM+ glucosamine sulfate, can reduce the fragrant consumption of analgesic Kapp, even can be without analgesic.U.S.4559329 thinks that MSM has effect in diarrhoea, gastrointestinal distress, hyperchlorhydria, food and drug allergy, environment allergy, hypertension, insect bite wound, arthritis etc.WO 94/05250 proposes to reduce hair by MSM+DMSO+ cysteine hydrochloride+menthol+Oleum Ricini compound recipe and decreases and help natural on-off cycles of hair growth.WO 94/05292 suggestion prevents and treats human primary gastrointestinal cancers with the aqueous solution of MSM+ allopurinol.The U.S.5569679 patent overcomes snoring with 10-16%MSM solution.WO 94/05273 shows with MSM and DMSO aqueous solution can prevent and administer gastrointestinal damage etc.
Because the crowd that above invention adapts to is narrower, specific aim is stronger, and fails to comprise the better composition of recent known Overlay.
Summary of the invention
The purpose of this invention is to provide a kind of dimethyl sulfone optimized overlap-add prescription at different crowd; the dimethyl sulfone sulfur supplement of this prescription and stack health product thereof have more effectively stack to body-care and form oligomeric chitosan, vitamin E, tea polyphenols, taurine etc., thereby enlarge its application.As slow down aging, beauty treatment, resisting fatigue, radioprotective, improve the health food of health cares such as gastrointestinal function, mutation, blood pressure regulation.Thereby eliminate symptoms such as the human senility, skin aging, immunity degradation, fatigue, sudden change, the gastrointestinal function that are caused by oxygen-derived free radicals are uncomfortable, collagen deficiency.
Technical scheme of the present invention is with composite series health-care products of making such as dimethyl sulfone and oligomeric chitosan (oligochitosan), Fructus Vitis viniferae amine hydrochlorate, Fructus Vitis viniferae amine sulfate, chondroitin sulfate, vitamin A, vitamin C, vitamin E, tea polyphenols, taurine, dibastic sodium phosphate, marine organisms goods.
Effect of the present invention and benefit are that this series health-care products can be used as the sulfur supplement, thereby the physiologically active of sulfur-containing compound in the enhancing body, also can be used as the oxygen-derived free radicals remover, thereby reduce the harm that health is caused by oxygen-derived free radicals, and then this series health-care products has slow down aging, beauty treatment, resisting fatigue, inhibition hyperosteogeny, rheumatic arthritis, antiallergic, asthma, mutation and radiation-resistant health-care effect.
Dimethyl sulfone (MSM) can provide the sulfur of the glutathion of one of synthetic main antioxidant of human body.The glutathion of sulfur-bearing, vitamin A, vitamin C, vitamin E, superoxide dismutase, tea polyphenols, curcumin etc. can both be removed metabolism product---oxygen-derived free radicals.And vitamin C and vitamin E not only itself have the oxygen-derived free radicals of removing ability, and have synergism with other antioxidant.
Dimethyl sulfone can suppress the organized enzyme that melanin generates, thereby prevents the deposition of melanin at skin.
Dimethyl sulfone not only can provide the sulfur of synthetic sulfur-bearing antioxidant, it can correct acetylcholine simultaneously---choline acyl ester balance, thereby the too much lactic acid that motion is produced is in time eliminated, and the contraction fat of muscle, the metabolism of carbohydrate are normally carried out, and motion time institute's energy requirement is provided.
The specific embodiment
Below in conjunction with technical scheme, be described in detail most preferred embodiment of the present invention.
Embodiment 1: dimethyl sulfone (MSM)---sulfur supplement
With dimethyl sulfone crystal 2 Kg dress capsule or tabletting, every/sheet is 500mg, totally 4000/sheet.Every day, secondary began each one, after 3-5 days, and each two.Looking the personal considerations can suitably increase and decrease.This example is suitable for the crowd who generally needs to replenish sulfur.
Embodiment 2: dimethyl sulfone stack slow down aging aesthetic health care food
The present invention is composite with dimethyl sulfone (MSM) and oligomeric chitosan, Fructus Vitis viniferae amine hydrochlorate, tea polyphenols vitamin E, vitamin C, incapsulates, and makes the health food of slow down aging beauty treatment.
Composition, content, method for making and the instructions of taking of the dimethyl sulfone health food that has provided the slow down aging beauty treatment that this example is detailed.
Concrete each component content scope (percentage by weight %) and each composition optimum of every/sheet are as follows:
Composition title content range (%) optimum (mg)
Dimethyl sulfone (MSM) 10-80 250
Oligomeric chitosan 8-50 100
Glucosamine hydrochloride 8-50 90
Vitamin C 1-30 10
Vitamin E 1-20 25
Tea polyphenols 0-20 25
Its concrete steps are: capsule is in room temperature 20-26 ℃ preparation, dimethyl sulfone and oligomeric chitosan to be put into fully mixing of batch mixer before the preparation, be ground into fine powder then, glucosamine hydrochloride is ground into fine powder separately, according to the above ratio all materials are added the batch mixer mix homogeneously then, the material that mixes is incapsulated, or tablet forming, every (sheet) 500mg.The raw materials used food stage that is, operation need to carry out in gnotobasis.
The suggestion consumption: every day secondary, begin each one, after 3-5 days, each two.Looking the personal considerations can suitably increase and decrease.
This delaying sanility of filling a prescription, and the effect of beauty treatment is arranged.
Embodiment 3: dimethyl sulfone stack fatigue resistant health food
The present invention is composite with MSM and Fructus Vitis viniferae amine sulfate, oligomeric chitosan, taurine, dibastic sodium phosphate, vitamin C, vitamin E, makes antifatigue dimethyl sulfone health food.
The composition, content, method for making and the instructions of taking that have provided the dimethyl sulfone health food that does fatigue that this example is detailed.
Concrete each component content scope (percentage by weight %) and each composition optimum of every/sheet are as follows:
Composition title content range (%) optimum (mg)
Dimethyl sulfone 10-70 250
Glucosamine sulfate 5-50 90
Oligomeric chitosan 5-50 50
Taurine 5-20 50
Dibastic sodium phosphate 5-20 25
Vitamin C 5-30 25
Vitamin E 1-20 10
Its concrete steps are: capsule is in room temperature 20-26 ℃ preparation, dimethyl sulfone and glucosamine sulfate to be ground into fine powder before the preparation, again with the abundant mixing of oligomeric chitosan, according to the above ratio all materials are added the batch mixer mix homogeneously then, the material that mixes is incapsulated, or tablet forming, every (sheet) 500mg.The raw materials used food stage that is, operation need to carry out in gnotobasis.
Motion, the first two hour clothes of working, each 2-3 grain.Taking my sensation of back before also visual several times suitably increases and decreases.Be suitable for the confirmed fatigue crowd, athlete and motion, the people that labor intensity is big can slow down motion back fatigue, muscular soreness.
Embodiment 4: dimethyl sulfone stack arthritis health food
The present invention is re-dubbed the health food that helps the arthritic with dimethyl sulfone and oligomeric chitosan, Fructus Vitis viniferae amine sulfate, chondroitin sulfate, vitamin C.
This example is detailed has provided composition, content, method for making and the instructions of taking that helps arthritic dimethyl sulfone health food.
Concrete each component content scope (percentage by weight %) and each composition optimum of every/sheet are as follows:
Composition title content range (%) optimum (mg)
Dimethyl sulfone 10-60 150
Oligomeric chitosan 10-60 150
Glucosamine sulfate 10-30 100
Chondroitin sulfate 10-20 60
Vitamin C 5-10 40
Its concrete steps are: capsule is in room temperature 20-26 ℃ preparation, dimethyl sulfone, oligomeric chitosan and Fructus Vitis viniferae amine sulfate to be mixed before the preparation and be ground into fine powder, according to the above ratio all materials are added the batch mixer mix homogeneously then, the material that mixes is incapsulated, or tablet forming, every (sheet) 500mg.The raw materials used food stage that is, operation need to carry out in gnotobasis.
Suggestion consumption: two of every days, each one, multiplicable when needing.
This prescription is suitable for crowds such as arthritis, hyperosteogeny, rheumatic arthritis.
Embodiment 5: dimethyl sulfone stack antiallergic, asthma health food
The present invention is composite with dimethyl sulfone and vitamin C, vitamin E, makes the health food of antiallergic, asthma.
This example is detailed has provided dimethyl sulfone stack antiallergic, composition, content, method for making and the instructions of taking of asthma health food.
Concrete each component content scope (percentage by weight %) and each composition optimum of every/sheet are as follows:
Composition title content range (%) optimum (mg)
Dimethyl sulfone 60-90 350
Vitamin C 8-30 125
Vitamin E 2-10 25
Its concrete steps are: capsule will be ground into fine powder in room temperature 20-26 ℃ preparation with dimethyl sulfone before the preparation, according to the above ratio all materials is added the batch mixer mix homogeneously then, the material that mixes is incapsulated, or tablet forming, every (sheet) 500mg.The raw materials used food stage that is, operation need to carry out in gnotobasis.
The suggestion consumption: every day secondary, each one, the contact allergy thing or asthma before and after double.
This prescription can be alleviated allergy such as food, medicine, pollen, environment, to asthma person's Castor Oil trachea, lung film.
Embodiment 6: dimethyl sulfone stack mutation, anti-radiation health care food
The present invention with dimethyl sulfone and oligomeric chitosan, chitosan, marine organisms goods, chondroitin sulfate, vitamin C, vitamin E, vitamin A, be re-dubbed mutation, anti-radiation health care food.
This example is detailed has provided dimethyl sulfone stack mutation, the composition of anti-radiation health care food, content, method for making and instructions of taking.
Concrete each component content scope (percentage by weight %) and each composition optimum of every/sheet are as follows:
Composition title content range (%) optimum (mg)
Dimethyl sulfone 5-80 250
Oligomeric chitosan 5-40 100
Chitosan 5-40 50
Marine organisms goods 0.5-20 25
Chondroitin sulfate 0.5-10 25
Vitamin C 2-20 25
Vitamin E 1-10 15
Vitamin A 1-10 10
Its concrete steps are: capsule is in room temperature 20-26 ℃ preparation, dimethyl sulfone, oligomeric chitosan to be ground into fine powder before the preparation, according to the above ratio all materials be added the batch mixer mix homogeneously then, the material that mixes is incapsulated, or tablet forming, every (sheet) 500mg.The raw materials used food stage that is, operation need to carry out in gnotobasis.
The suggestion consumption: every day secondary, begin each one, after 3-5 days each two, looking the situation of taking can suitably increase and decrease.
This prescription can be used as the health food of sudden change, radiation and human primary gastrointestinal cancers, breast carcinoma.

Claims (6)

1, dimethyl sulfone sulfur supplement and stack health product thereof, it is characterized in that with dimethyl sulfone and oligomeric chitosan, Fructus Vitis viniferae amine hydrochlorate, Fructus Vitis viniferae amine sulfate, chondroitin sulfate, tea polyphenols, taurine, dibastic sodium phosphate, marine organisms goods, vitamin A, vitamin C, vitamin E, etc. composite making.
2, dimethyl sulfone sulfur supplement according to claim 1 and stack health product thereof, it is characterized in that the compositions that comprises that dimethyl sulfone and oligomeric chitosan, glucosamine sulfate, tea polyphenols, vitamin C, vitamin E are re-dubbed, specifically each composition proportion is (percentage by weight %):
Dimethyl sulfone 10-80
Oligomeric chitosan 8-50
Glucosamine sulfate 8-50
Vitamin C 1-30
Vitamin E 1-20
Tea polyphenols 0-20
3, dimethyl sulfone sulfur supplement according to claim 1 and stack health product thereof; it is characterized in that the compositions that comprises that dimethyl sulfone and oligomeric chitosan, glucosamine sulfate, taurine, dibastic sodium phosphate, vitamin C, vitamin E are re-dubbed, specifically each composition proportion is (percentage by weight %):
Dimethyl sulfone 10-70
Oligomeric chitosan 5-50
Glucosamine sulfate 5-50
Taurine 5-20
Dibastic sodium phosphate 5-20
Vitamin C 5-30
Vitamin E 1-20
4, dimethyl sulfone sulfur supplement according to claim 1 and stack health product thereof, it is characterized in that the compositions that comprises that dimethyl sulfone and oligomeric chitosan, glucosamine sulfate, chondroitin sulfate, vitamin C are re-dubbed, specifically each composition proportion is (percentage by weight):
Dimethyl sulfone 10-60
Oligomeric chitosan 10-60
Glucosamine sulfate 10-30
Chondroitin sulfate 10-20
Vitamin C 5-10
5, dimethyl sulfone sulfur supplement according to claim 1 and stack health product thereof is characterized in that the compositions that comprises that dimethyl sulfone and vitamin C, vitamin E are re-dubbed, and specifically each composition proportion is (percentage by weight %):
Dimethyl sulfone 60-90
Vitamin C 8-30
Vitamin E 2-10
6, dimethyl sulfone sulfur supplement according to claim 1 and stack health product thereof, it is characterized in that the compositions that comprises that dimethyl sulfone and oligomeric chitosan, chitosan, marine organisms goods, chondroitin sulfate, vitamin C, vitamin A, vitamin E are re-dubbed, specifically each composition proportion is (percentage by weight %):
Dimethyl sulfone 5-80
Oligomeric chitosan 5-40
Chitosan 5-40
Marine organisms goods 0.5-20
Chondroitin sulfate 0.5-10
Vitamin C 2-20
Vitamin E 1-10
Vitamin A 1-10
CN02158855A 2002-12-25 2002-12-25 Dimethyl-sulfone sulfide supplementary agent and its overlapped health articles Pending CN1425386A (en)

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Application Number Priority Date Filing Date Title
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CN02158855A CN1425386A (en) 2002-12-25 2002-12-25 Dimethyl-sulfone sulfide supplementary agent and its overlapped health articles

Publications (1)

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CN1425386A true CN1425386A (en) 2003-06-25

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115546A3 (en) * 2004-05-24 2006-03-16 Gen Topics Srl Dimethyl sulfone for the treatment of rosacea
CN102100696A (en) * 2009-12-17 2011-06-22 许宏昌 Bone joint maintenance composite containing dimethyl sulfone
CN112584825A (en) * 2018-08-17 2021-03-30 李昇薰 Composition for preventing or improving obesity, fatty liver and diabetes comprising methylsulfonylmethane
CN115024993A (en) * 2022-05-12 2022-09-09 广州銮滢化妆品有限公司 Anti-saccharification sulfo composition and preparation method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005115546A3 (en) * 2004-05-24 2006-03-16 Gen Topics Srl Dimethyl sulfone for the treatment of rosacea
CN102100696A (en) * 2009-12-17 2011-06-22 许宏昌 Bone joint maintenance composite containing dimethyl sulfone
CN112584825A (en) * 2018-08-17 2021-03-30 李昇薰 Composition for preventing or improving obesity, fatty liver and diabetes comprising methylsulfonylmethane
CN115024993A (en) * 2022-05-12 2022-09-09 广州銮滢化妆品有限公司 Anti-saccharification sulfo composition and preparation method thereof
CN115024993B (en) * 2022-05-12 2023-09-01 广州銮滢化妆品有限公司 Anti-saccharification thio composition and preparation method thereof

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