CN1413469A - Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree - Google Patents

Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree Download PDF

Info

Publication number
CN1413469A
CN1413469A CN 02135218 CN02135218A CN1413469A CN 1413469 A CN1413469 A CN 1413469A CN 02135218 CN02135218 CN 02135218 CN 02135218 A CN02135218 A CN 02135218A CN 1413469 A CN1413469 A CN 1413469A
Authority
CN
China
Prior art keywords
herbal medicine
fruit tree
chinese herbal
disease
standby
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN 02135218
Other languages
Chinese (zh)
Other versions
CN1218644C (en
Inventor
牛西午
段泽敏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INSTITUTE OF COMPREHENSIVE UTILIZATION OF AGRICULTURAL PRODUCTS SHANXI ACADEMY OF AGRICULTURAL SCIENCES
Original Assignee
INSTITUTE OF COMPREHENSIVE UTILIZATION OF AGRICULTURAL PRODUCTS SHANXI ACADEMY OF AGRICULTURAL SCIENCES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INSTITUTE OF COMPREHENSIVE UTILIZATION OF AGRICULTURAL PRODUCTS SHANXI ACADEMY OF AGRICULTURAL SCIENCES filed Critical INSTITUTE OF COMPREHENSIVE UTILIZATION OF AGRICULTURAL PRODUCTS SHANXI ACADEMY OF AGRICULTURAL SCIENCES
Priority to CN 02135218 priority Critical patent/CN1218644C/en
Publication of CN1413469A publication Critical patent/CN1413469A/en
Application granted granted Critical
Publication of CN1218644C publication Critical patent/CN1218644C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A Chinese-medicinal cream for preventing and treating the rot of fruit tree is prepared from the 2,4-D(2,4-dichlorophenoxyacetic acid) as plant cell auxin (4-10 ppm) and 6 Chinese medicinal materials including oriental wormwood, phellodendron bark, flavescent sophora root, etc. Its advantages are high effect and no environmental pollution.

Description

The Chinese herbal medicine paste preparation of control fruit tree putrefaction disease
Technical field
The invention belongs to the phyteral bactericide, relate generally to the bactericide that is used to prevent and treat fruit tree disease of rotting fruit tree.
Background technology
Rot is the main trunk disease of fruit tree, and one band widely takes place popularly in China and Southeast Asia, and after the morbidity of orchard, the lighter's tree vigo(u)r is weak, and growth slows down, the death of weight person plant, and the destruction of full garden is called as the cancer of fruit tree.To the control of fruit tree putrefaction disease, the general employing strengthened the orchard rich water quality management, strengthens tree vigo(u)r, removes cause of disease at present, and multinomial technical measures such as spraying fungicide and sick scar processing are carried out integrated control.Wherein, it is the method for widely using on producing that sick scar is handled, and the medicament that control is used has aqua, pulvis and paste, from composition three classes are arranged, experienced continuous development and change process, the first kind is based on traditional organo-arsenic, wherein, with the asomate be main representative.Up to the present, asomate remains the classical medicament of preventing and treating rot, but because of its longevity of residure long, be difficult for to decompose, easily cause pollution, thereby national departments concerned is made the regulation of " forbidding producing, forbidding selling, banning use of " to environment and food chain; Second class is pulvis or the paste that is mixed and forms with asomate and other organic and inorganic compound.Wherein, be representative with copper, arsenic mixture preparation; The 3rd class promptly belongs to popular environmental protection series products at present.Wherein, having necessarily representationally, is to be the tpn of main sterilization component with amino acid and derivative thereof, and after this class substance decomposition, the amino acid that dissociates can be the plant absorbing metabolism, has better solved sterilization and environmental relation to a certain extent.In every case handle the common problem of medicament of disease scar with liquid form, it at first is permeability, next is the continuation of drug effect, and wherein permeability generally is to solve by the mode that adds surfactant, and the continuation of drug effect then is that the steady chemical structure by medicament itself solves.So, still produce a series of environmental problems inevitably.
On the other hand, China is vast in territory, weather category is complicated and changeable, and also there are significant difference in geographical position and ecological environmental condition that fruit tree distributes, particularly in the high and cold area that cools, often freeze injury is one of main inducing of fruit tree putrefaction disease generation, and general water soluble medicament, because of too very brief in the effective acting time of tree body, thereby causing bactericidal effect not thorough, the characteristic of disease recurrence rate of sick scar is higher.Now prove; the recurrence of fruit tree putrefaction disease is owing to the cause of disease activity that remains in xylem causes; therefore research and design is a kind of promptly meets the environmental protection basic demand; the sustainable again cause of disease of effectively killing; reach and adopt the conventional control method to receive the purpose of " once scrape and control; lasting protection ", to satisfy the needs that the control of different ecological zone is used.
Chinese herbal medicine has the rich in natural resources advantage in China, it has been established that: but the plant of China's hyoscine has 11118 kinds, have 291 sections with the angiosperm for example China, 3082 belong to and 24357 kinds, wherein medicinal person has 213 sections, 1957 belong to and 10027 kinds (containing 1063 following grades of kind), and what have bactericidal action in these plants has kind more than 1000 approximately.And, contain the active ingredient that can promote the plant tissue healing in the Chinese herbal medicine.Therefore, rely on the Chinese herbal medicine natural resource advantages of China's abundant and traditional Chinese herbal medicine theory, utilize the bactericidal action of natural plants and promote the healing effect, rely on the basis for the control of carrying out fruit tree putrefaction disease provides to support.Chinese herbal medicine also in this sick control more at present practice, and obtains certain progress; But the common problem that exists is that higher, the contained effective ingredient of preparation cost is lower.
Summary of the invention
The technical problem to be solved in the present invention is the Chinese herbal and crude drugs preparations scheme that proposes the control fruit tree putrefaction disease.
The present invention program's particular content is, the Chinese herbal medicine paste preparation of control fruit tree putrefaction disease comprises to the former host with inhibitory or killing effect of fruit tree putrefaction disease with as the conventional auxiliary material of forming agent.Wherein the proportioning that reaches according to part by weight umber meter with raw material of selected host is: oriental wormwood 1-9 periploca spium 1-2.5 golden cypress 1-3 kuh-seng 1-3 reticulate millettia 1-2.5 thunder godvine 1-2.5; Auxin substance 2,4-D (2,4-dichlorphenoxyacetic acid) 4-10ppm.Also contain surface reactive material 2-3 part in the selected auxiliary material.Like this, selected six kinds of hosts have a stronger inhibitory action to fruit tree putrefaction disease is former, and auxin substance can promote the formation of callus, and surface-active substance mass-energy strengthens the permeability of Chinese herbal medicine active substance; The technical problem that the present invention is proposed is resolved.
The proportioning that conventional auxiliary material of the present invention reaches according to part by weight umber meter is: lanolin 60-160, sulphur 4-8 rosin 2-7.5 talcum powder 2-8 paraffin 1-4 glacial acetic acid 2-3.This is a kind of selection of suitable aforementioned schemes Chinese herbal medicine paste preparation.
The manufacturing process of Chinese herbal medicine paste preparation of the present invention is as follows: pulverize after the oriental wormwood, periploca spium, golden cypress, kuh-seng, reticulate millettia, the thunder godvine that collect are dried in the shade, cross 80 mesh sieves, weighing, mixing, standby; With auxin substance 2,4-D (2,4 dichlorophenoxyacetic acid) dissolving, it is standby to be diluted to 100mg/1000ml; According to the quantity that requires, surface reactive material (as dodecyl sodium sulfate etc.) and talcum powder are added the said herbal medicine behind the mixing and stir, add glacial acetic acid and contain the solution of auxins active substance according to the quantity that requires then, and stir, it is standby to get mixture A; Take by weighing rosin according to required amount, and under 60-80 ℃ of heating condition, make it to melt, and adding paraffin also makes it thawing, standby; Take by weighing lanolin according to required amount, and make it to melt under 40-60 ℃ of heating condition, and add rosin, the mixture A that has melted successively, add sulphur at last, stir, the suitable container of packing into, cooling get final product.Obviously this is the lower process program of a kind of cost of manufacture.
The present invention has stronger inhibiting Chinese herbal medicine through screening to apple decay cause of disease bacterium, the auxin substance of adapted and surface reactive material with it, the auxiliary material of suitable Chinese herbal medicine paste preparation, and corresponding brief manufacture craft, make the gained paste can effectively control the generation of fruit tree putrefaction disease, and can promote the quickly-healing of disease scar, satisfy the specification requirement of fruit tree putrefaction disease control, correlation technique and product are suitable for geographical position that fruit tree distributes and ecotope significant difference, condition that weather category is complicated and changeable.Particularly in the high and cold area that cools, freeze injury is one of main inducing of fruit tree putrefaction disease generation, and general water soluble medicament because of too very brief in the effective acting time of tree body, thereby causes bactericidal effect not thorough, and the characteristic of disease recurrence rate of sick scar is higher.Now prove; the recurrence of fruit tree putrefaction disease is owing to the cause of disease activity that remains in xylem causes; therefore the present invention program can adapt to the environmental protection basic demand; the sustainable again cause of disease of effectively killing; reach and adopt the conventional control method to receive the purpose of " once scrape and control; lasting protection ", satisfy the needs that the control of different ecological zone is used.
Embodiment
One of embodiment:
This routine bactericide is used for the field control of apple canker (Valsa mali Myabe et Yamada).
Major ingredient kind and part by weight are: oriental wormwood: periploca spium: golden cypress: kuh-seng: reticulate millettia: thunder godvine=1: 1: 1: 1: 1: 1; Add in addition 2, the 4-D consumption is 4ppm.
Supplementary product kind and part by weight are: lanolin 60, sulphur 4, rosin 2, talcum powder 2, paraffin 1, glacial acetic acid 2, surface reactive material 2.
Manufacturing process is: pulverize after the oriental wormwood, periploca spium, golden cypress, kuh-seng, reticulate millettia, the thunder godvine that collect are dried in the shade, cross 80 mesh sieves, weighing, mixing, standby; With auxin substance 2,4-D (2,4 dichlorophenoxyacetic acid) dissolving, it is standby to be diluted to 100mg/1000ml; According to the quantity that requires, surface reactive material (as dodecyl sodium sulfate etc.) and talcum powder are added the said herbal medicine behind the mixing and stir, add glacial acetic acid and contain the solution of auxins active substance according to the quantity that requires then, and stir, it is standby to get mixture A; Take by weighing rosin according to required amount, and under 60-80 ℃ of heating condition, make it to melt, and adding paraffin also makes it thawing, standby; Take by weighing lanolin according to required amount, and make it to melt under 40-60 ℃ of heating condition, and add rosin, the mixture A that has melted successively, add sulphur at last, stir, the suitable container of packing into, cooling get final product.
Experimental selection was carried out on the green apple tree in 9 years, its disease index 2-3 level, employing is scraped pico farad and is handled the disease scar, use this routine Chinese herbal medicine paste directly to be applied on the sick scar of striking off the disease skin, the contrast medicament is 50 times of dilutions of 40% wettable asomate, handle the back and observed state of an illness spread scenarios in 7-10 days, 1 year " Invest, Then Investigate " drug effect and disease relapse rate and callus form width.Its result is as shown in table 1:
This example of table 1 is prevented and treated the apple valsa canker effect
Handle Handle number Significant figure The recurrence number Efficient Recurrence rate The callus width
The present invention 222 217 ?5 ?97.75% ?2.25% ?25mm
Contrast 120 ?114 ?6 ?95.0% ?5.0% ?18mm
Therefore:
1. this routine preparation can be used for the field control of apple valsa canker;
2. this routine preparation, the effect of preventing and treating apple valsa canker is better than asomate;
3. this routine preparation is better than asomate to apple valsa canker scar healing effect.
Two of embodiment:
This routine bactericide is used for the field control of apple canker (Valsa mali Myabe et Yamada).
Major ingredient kind and ratio are: oriental wormwood: periploca spium: golden cypress: kuh-seng: reticulate millettia: thunder godvine=5: 1.5: 2: 1.5: 1: 1.5; 2, the 4-D consumption is 8ppm.
Supplementary product kind and ratio are: lanolin 75, sulphur 6, rosin 5, talcum powder 5, paraffin 3, glacial acetic acid 2, surface reactive material 2.
Manufacturing process is: (with one of embodiment)
Test in selecting 13 years green apple trees to carry out, disease index 2-3 level, employing is scraped pico farad and is handled the disease scar, use this routine Chinese herbal medicine paste directly to be applied on the sick scar of striking off the disease skin, the contrast medicament is 50 times of dilutions of 40% wettable asomate, handle the back and observed state of an illness spread scenarios in 7-10 days, 1 year " Invest, Then Investigate " drug effect and disease relapse rate and callus form width.Its result is as shown in table 2:
This example of table 2 is prevented and treated the apple valsa canker effect
Handle Handle number Significant figure The recurrence number Efficient Recurrence rate The callus width
The present invention 147 ?141 ?6 ?95.92% ?4.08% ?22mm
Contrast 82 ?77 ?5 ?93.9% ?6.10% ?16mm
Three of embodiment:
This routine bactericide is used for the field control of pear tree rot.
Major ingredient kind and ratio are: oriental wormwood: periploca spium: golden cypress: kuh-seng: reticulate millettia: thunder godvine=9: 2.5: 3: 3: 2.5: 2.5; 2, the 4-D consumption is 10ppm.
Supplementary product kind and ratio are: lanolin 160, sulphur 8, rosin 7.5, talcum powder 8, paraffin 4, glacial acetic acid 3, surface reactive material 3.
Manufacturing process is: (with one of embodiment)
8 years living pear trees of experimental selection carry out, and disease index is the 2-3 level, and employing is scraped pico farad and handled the disease scar, and the Chinese herbal medicine paste that this is routine directly is applied on the sick scar of striking off the disease skin, and the contrast medicament is 50 times of dilutions of 40% asomate wetting powder.Handle observing effect after 7-10 days, 1 year " Invest, Then Investigate " drug effect and disease relapse situation and callus form width.Its effect is as shown in table 3:
Table 3 a routine field control pear tree rot effect
Handle Handle number Significant figure The recurrence number Efficient Recurrence rate The callus width
The present invention 125 ?123 ????2 ?98.4% ?1.6% ?18mm
Asomate 56 ?54 ????2 ?96.4% ?3.6% ?13mm
Therefore:
1. this routine preparation can be used for the field control of pear tree rot;
2. this routine preparation, control pear tree rot efficient, recurrence rate is consistent with asomate;
3. this routine preparation is better than asomate to the healing effect of pear tree rot scar.

Claims (3)

1. the Chinese herbal medicine paste preparation of control fruit tree putrefaction disease comprises to the former host with inhibitory or killing effect of fruit tree putrefaction disease with as the conventional auxiliary material of forming agent; It is characterized in that: host is oriental wormwood (Artemisia Capillaris Thunb), periploca spium (Periploca Sepium.Bge.,), golden cypress (Phellodendron Amurense Rupr.,), basic stitch or fungicide active ingredient, the plain class material of plant cell growth and a spot of surfactant (lauryl sodium sulfate etc.) of kuh-seng (Sophora Flavescens Ait.), reticulate millettia (Spatholobus Suberectus Dunn.), thunder godvine (TriplerygiumWilfordii Hook.f.); Its consumption (according to weight ratio) is: oriental wormwood (Artemisia Capillaris Thunb) 1--9, periploca spium (Periploca Sepium.Bge.,) 1--2.5, golden cypress (Phellodendron Amurense Rupr.,) 1--3, kuh-seng (SophoraFlavescens Ait.,) 1--3, reticulate millettia (Spatholobus Suberectus Dunn.) 1-2.5, thunder godvine (Triplerygium Wilfordii Hook.f.) 1--2.5, the plain material 2 of plant cell growth, 4-D (2,4 dichlorophenoxyacetic acid) 4-10ppm.
2. prevent and treat the Chinese herbal medicine paste preparation of fruit tree putrefaction disease according to claim 1; It is characterized in that: the proportioning that described conventional auxiliary material reaches according to part by weight umber meter is: lanolin 60-160, sulphur 4-8 rosin 2-7.5 talcum powder 2-8 paraffin 1-4 glacial acetic acid 2-3.
3. prevent and treat the Chinese herbal medicine paste preparation of fruit tree putrefaction disease as claimed in claim 1 or 2; It is characterized in that: the manufacturing process of described Chinese herbal medicine paste preparation is as follows: pulverize after the oriental wormwood, periploca spium, golden cypress, kuh-seng, reticulate millettia, the thunder godvine that collect are dried in the shade, cross 80 mesh sieves, weighing, mixing, standby; With auxin substance 2,4-D (2,4 dichlorophenoxyacetic acid) dissolving, it is standby to be diluted to 100mg/1000ml; According to the quantity that requires, surface reactive material (as dodecyl sodium sulfate etc.) and talcum powder are added the said herbal medicine behind the mixing and stir, add glacial acetic acid and contain the solution of auxins active substance according to the quantity that requires then, and stir, it is standby to get mixture A; Take by weighing rosin according to required amount, and under 60-80 ℃ of heating condition, make it to melt, and adding paraffin also makes it thawing, standby; Take by weighing lanolin according to required amount, and under 40-60 ℃ of heating condition, make it to melt, and add rosin, the mixture A that has melted successively, add sulphur at last, stir pack into suitable container, cooling.
CN 02135218 2002-06-14 2002-06-14 Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree Expired - Fee Related CN1218644C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 02135218 CN1218644C (en) 2002-06-14 2002-06-14 Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 02135218 CN1218644C (en) 2002-06-14 2002-06-14 Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree

Publications (2)

Publication Number Publication Date
CN1413469A true CN1413469A (en) 2003-04-30
CN1218644C CN1218644C (en) 2005-09-14

Family

ID=4748074

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 02135218 Expired - Fee Related CN1218644C (en) 2002-06-14 2002-06-14 Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree

Country Status (1)

Country Link
CN (1) CN1218644C (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317955C (en) * 2005-12-24 2007-05-30 中北大学 Broad spectrum vegetable insecticide, and its prepn. method
CN102379283A (en) * 2011-09-21 2012-03-21 南京红太阳股份有限公司 Water-soluble paste agent containing paraquat dichloride
CN101611724B (en) * 2008-06-23 2012-07-04 中国科学院华南植物园 Environmentally-friendly phytochemical pasty biopesticide and preparation method thereof
CN101623000B (en) * 2009-07-16 2012-07-25 西北农林科技大学 Eradicant for rot disease of apple tree
CN103524169A (en) * 2012-07-04 2014-01-22 史占彪 Missible oil liquid capable of preventing and treating apple valsa canker, as well as preparation method of missible oil liquid
CN105851079A (en) * 2016-05-09 2016-08-17 山西省农业科学院果树研究所 Bactericide for controlling fruit tree rotten diseases and preparation method and application method of bactericide for controlling fruit tree rotten diseases
CN113973851A (en) * 2021-11-29 2022-01-28 晋中职业技术学院 Chinese herbal medicine ointment for preventing and treating fruit tree rot disease and preparation method and application thereof
CN114176095A (en) * 2021-12-24 2022-03-15 华夏瑞天(北京)生物科技有限公司 Bacteriostatic liquid for preventing and treating fungal plant diseases and preparation method and use method thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1317955C (en) * 2005-12-24 2007-05-30 中北大学 Broad spectrum vegetable insecticide, and its prepn. method
CN101611724B (en) * 2008-06-23 2012-07-04 中国科学院华南植物园 Environmentally-friendly phytochemical pasty biopesticide and preparation method thereof
CN101623000B (en) * 2009-07-16 2012-07-25 西北农林科技大学 Eradicant for rot disease of apple tree
CN102379283A (en) * 2011-09-21 2012-03-21 南京红太阳股份有限公司 Water-soluble paste agent containing paraquat dichloride
CN102379283B (en) * 2011-09-21 2014-07-23 南京红太阳股份有限公司 Water-soluble paste agent containing paraquat dichloride
CN103524169A (en) * 2012-07-04 2014-01-22 史占彪 Missible oil liquid capable of preventing and treating apple valsa canker, as well as preparation method of missible oil liquid
CN103524169B (en) * 2012-07-04 2015-07-22 史占彪 Missible oil liquid capable of preventing and treating apple valsa canker, as well as preparation method of missible oil liquid
CN105851079A (en) * 2016-05-09 2016-08-17 山西省农业科学院果树研究所 Bactericide for controlling fruit tree rotten diseases and preparation method and application method of bactericide for controlling fruit tree rotten diseases
CN105851079B (en) * 2016-05-09 2018-09-21 山西省农业科学院果树研究所 A kind of fungicide and its preparation and application of prevention fruit tree putrefaction disease
CN113973851A (en) * 2021-11-29 2022-01-28 晋中职业技术学院 Chinese herbal medicine ointment for preventing and treating fruit tree rot disease and preparation method and application thereof
CN114176095A (en) * 2021-12-24 2022-03-15 华夏瑞天(北京)生物科技有限公司 Bacteriostatic liquid for preventing and treating fungal plant diseases and preparation method and use method thereof

Also Published As

Publication number Publication date
CN1218644C (en) 2005-09-14

Similar Documents

Publication Publication Date Title
CN1331396C (en) Pollution-less pesticide fertilizer for preventing and controlling blight and its production process
KR100852767B1 (en) Insecticidal and fertilizing composition and method of killing insects and fertilization using the same
CN102649654A (en) Traditional Chinese medicine organic fertilizer
CN103833459A (en) Drug fertilizer composition for preventing and treating green turf diseases and application thereof
CN102007926B (en) Liquid formulation containing emamectin benzoate for trunk injection
CN106069427B (en) A method of reducing Brown Rice cadmium content
CN102992868B (en) Specific fermented pesticide fertilizer for soybeans
CN106718732A (en) A kind of dedicated substrate of preserved vegetable nursery
CN102633576A (en) Soil nutrient protective agent for preventing harm of acid rain
CN1218644C (en) Chinese herbal medicine ointment preparation for preventing and curing rot of fruit tree
CN100479661C (en) Environment-protective crop alimentary bacteriocide and application thereof
CN101233848A (en) Safety nuisance free biogas slurry liquid insecticide and preparation thereof
CN110150330A (en) A kind of compound botanical source bactericide and preparation method thereof
CN106995339A (en) Cultivation of fruit tree Nutrition Soil and preparation method thereof
CN101233866A (en) Matrine agent plant pesticide special for killing cabbage worm and preparation thereof
CN106588367A (en) Special fertilizer for promoting growth of grapes
CN107372653A (en) Medicament and the application of snail are prevented and treated in officinal dendrobium stem plantation production
CN1252002C (en) Plant-sourced medicinal fertilizer
CN110537551A (en) Fermentation liquor composition
CN106242671A (en) A kind of magnetization charcoal base manure and preparation method thereof
CN109206231A (en) A kind of Chinese herbal medicine medical stone type microbial bacterial agent and preparation method thereof
CN102365939B (en) Botanical sterilization preparation and application thereof for controlling anthracnose of grape
CN108718877B (en) Method for preventing peach tree gummosis
CN106220423A (en) A kind of Lagerstroemia indica L. special fertilizer and its preparation method and application
CN104761329A (en) Organic/inorganic bio-fertilizer specially-used for tobacco and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050914

Termination date: 20110614