CN1410137A - 热疗用纳米磁热种子及其制备方法和用途 - Google Patents
热疗用纳米磁热种子及其制备方法和用途 Download PDFInfo
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- CN1410137A CN1410137A CN 01134012 CN01134012A CN1410137A CN 1410137 A CN1410137 A CN 1410137A CN 01134012 CN01134012 CN 01134012 CN 01134012 A CN01134012 A CN 01134012A CN 1410137 A CN1410137 A CN 1410137A
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- nano
- thermotherapy
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- heating seed
- surfactant
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- 238000000015 thermotherapy Methods 0.000 title claims abstract description 47
- 238000010438 heat treatment Methods 0.000 title claims description 67
- 238000002360 preparation method Methods 0.000 title claims description 18
- 206010028980 Neoplasm Diseases 0.000 claims abstract description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 29
- 239000004094 surface-active agent Substances 0.000 claims abstract description 25
- 238000002347 injection Methods 0.000 claims abstract description 14
- 239000007924 injection Substances 0.000 claims abstract description 14
- 239000007864 aqueous solution Substances 0.000 claims abstract description 8
- 238000005406 washing Methods 0.000 claims abstract description 5
- 238000001035 drying Methods 0.000 claims abstract description 3
- 239000000725 suspension Substances 0.000 claims abstract description 3
- 239000006247 magnetic powder Substances 0.000 claims description 35
- 238000002604 ultrasonography Methods 0.000 claims description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 239000006228 supernatant Substances 0.000 claims description 4
- 230000005308 ferrimagnetism Effects 0.000 claims description 3
- 230000005307 ferromagnetism Effects 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 claims description 3
- 235000019982 sodium hexametaphosphate Nutrition 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims description 3
- 238000002560 therapeutic procedure Methods 0.000 claims description 3
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 claims description 2
- 238000004062 sedimentation Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 abstract description 6
- 238000002156 mixing Methods 0.000 abstract description 2
- 239000008213 purified water Substances 0.000 abstract 2
- 239000000084 colloidal system Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 description 11
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 210000000683 abdominal cavity Anatomy 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 4
- 238000005303 weighing Methods 0.000 description 4
- 241000699666 Mus <mouse, genus> Species 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 238000007918 intramuscular administration Methods 0.000 description 3
- 210000001165 lymph node Anatomy 0.000 description 3
- 238000007920 subcutaneous administration Methods 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- 208000010507 Adenocarcinoma of Lung Diseases 0.000 description 2
- 241000700199 Cavia porcellus Species 0.000 description 2
- ZFZWKDFIUQMZHV-UHFFFAOYSA-M [Br-].[NH4+].C(CCCCCCCCCCCCCCC)[N+](CC1=CC=CC=C1)(C)C.[Br-] Chemical compound [Br-].[NH4+].C(CCCCCCCCCCCCCCC)[N+](CC1=CC=CC=C1)(C)C.[Br-] ZFZWKDFIUQMZHV-UHFFFAOYSA-M 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 239000000696 magnetic material Substances 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 201000005249 lung adenocarcinoma Diseases 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 239000011858 nanopowder Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000000771 oncological effect Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 01134012 CN1242820C (zh) | 2001-10-09 | 2001-10-09 | 热疗用纳米磁热种子及其制备方法和用途 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 01134012 CN1242820C (zh) | 2001-10-09 | 2001-10-09 | 热疗用纳米磁热种子及其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1410137A true CN1410137A (zh) | 2003-04-16 |
CN1242820C CN1242820C (zh) | 2006-02-22 |
Family
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Application Number | Title | Priority Date | Filing Date |
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CN 01134012 Expired - Fee Related CN1242820C (zh) | 2001-10-09 | 2001-10-09 | 热疗用纳米磁热种子及其制备方法和用途 |
Country Status (1)
Country | Link |
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CN (1) | CN1242820C (zh) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006015520A1 (fr) * | 2004-08-11 | 2006-02-16 | Yangde Zhang | Procédé de préparation de nanoparticules magnétiques de galactosyle-has contenant de l’adriamycine |
WO2007048326A1 (fr) * | 2005-10-25 | 2007-05-03 | Hong Zhu | Médicament ciblé nanométrique pour magnéto-thermothérapie de tumeurs malignes |
CN100372908C (zh) * | 2005-07-15 | 2008-03-05 | 东南大学 | 肿瘤磁致热疗用纳米发热剂的制备方法 |
CN102523790A (zh) * | 2011-09-30 | 2012-07-04 | 浙江大学 | 一种磁粉防伪烟草丸化种子的制备方法及丸化种子和检测方法 |
CN102523782A (zh) * | 2011-09-30 | 2012-07-04 | 浙江大学 | 一种双重荧光防伪丸化种子的制备方法及防伪种子和检测方法 |
CN102577702A (zh) * | 2011-10-28 | 2012-07-18 | 浙江大学 | 一种荧光磁粉双重防伪丸化种子的制备方法及丸化种子和检测方法 |
CN103058642A (zh) * | 2012-12-31 | 2013-04-24 | 山东建筑大学 | 一种基于微波肿瘤热疗的纳米热种子材料及其制备方法 |
-
2001
- 2001-10-09 CN CN 01134012 patent/CN1242820C/zh not_active Expired - Fee Related
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006015520A1 (fr) * | 2004-08-11 | 2006-02-16 | Yangde Zhang | Procédé de préparation de nanoparticules magnétiques de galactosyle-has contenant de l’adriamycine |
CN100372908C (zh) * | 2005-07-15 | 2008-03-05 | 东南大学 | 肿瘤磁致热疗用纳米发热剂的制备方法 |
WO2007048326A1 (fr) * | 2005-10-25 | 2007-05-03 | Hong Zhu | Médicament ciblé nanométrique pour magnéto-thermothérapie de tumeurs malignes |
CN102523790A (zh) * | 2011-09-30 | 2012-07-04 | 浙江大学 | 一种磁粉防伪烟草丸化种子的制备方法及丸化种子和检测方法 |
CN102523782A (zh) * | 2011-09-30 | 2012-07-04 | 浙江大学 | 一种双重荧光防伪丸化种子的制备方法及防伪种子和检测方法 |
CN102523782B (zh) * | 2011-09-30 | 2013-10-30 | 浙江大学 | 一种双重荧光防伪丸化种子的制备方法及防伪种子和检测方法 |
CN102577702A (zh) * | 2011-10-28 | 2012-07-18 | 浙江大学 | 一种荧光磁粉双重防伪丸化种子的制备方法及丸化种子和检测方法 |
CN103058642A (zh) * | 2012-12-31 | 2013-04-24 | 山东建筑大学 | 一种基于微波肿瘤热疗的纳米热种子材料及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN1242820C (zh) | 2006-02-22 |
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