CN1398629A - Changshuning capsule and its prepn - Google Patents

Changshuning capsule and its prepn Download PDF

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Publication number
CN1398629A
CN1398629A CN 02136219 CN02136219A CN1398629A CN 1398629 A CN1398629 A CN 1398629A CN 02136219 CN02136219 CN 02136219 CN 02136219 A CN02136219 A CN 02136219A CN 1398629 A CN1398629 A CN 1398629A
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China
Prior art keywords
capsule
changshuning
fructus cannabis
constipation
aloe powder
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CN 02136219
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CN1160111C (en
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周淡宜
王茵
徐水祥
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Zhejiang Academy of Medical Sciences
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Zhejiang Academy of Medical Sciences
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Priority to CNB02136219XA priority Critical patent/CN1160111C/en
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Publication of CN1160111C publication Critical patent/CN1160111C/en
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Expired - Fee Related legal-status Critical Current

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Abstract

Changchuning capsule is prepared with seed of Chinese dwarf flowering cherry, fructus cannabis and aloe powder. Its preparation process includes weighing the Chinese dwarf flowering cherry and fructus cannabis in certain proportion, washing, repeated decoction, filtering to obtain filtrate, merging filtrate, concentration, stoving, mixing with aloe powder, re-stoving the mixture to water content lower than 3-5%, crushing to 60-80 mesh and capsulizing. The present invention as one health food has the function of relaxing the bowels and is safe and and non-toxic.

Description

Changshuning capsule and preparation method thereof
Technical field
The present invention relates to a kind of Changshuning capsule and preparation method thereof.
Background technology
Keep stool unimpeded, in time remove the intestinal intoxication element, this can be of great benefit to good health and a long life.The main effect of large intestine is assimilate food moisture and inorganic salt in the residue, voids excreta.Food debris form feces and the process that excretes in, the wriggling of intestinal tube plays epochmaking effect.Old or body void after being ill, dryness-heat stagnating in the interior, deficiency of body fluid, the intestinal tube wriggling function weakens, and digestive juice secretion reduces, and regular meeting causes constipation with dry stool, difficult defecation.Some women can't promote the normal operation of blood and cause pipeline to owe logical owing to insufficiency of primordial QI.It is young and middle-aged because work strain, rule of life change and other Nervous and Mental Factors also can cause defecation not smooth.Food debris in constipation person's intestinal can generate the material of some insalubrity, as amine, guanidine etc. owing to can not in time remove under the effect of putrefaction bacteria.These materials can enter blood through intestinal absorption, arrive liver with blood flow; In case when exceeding the detoxification ability of liver, menses flow to into brain and body tissue again, influence brain function and cellular metabolism, cause multiple disease to take place, also can quicken aging.Simultaneously, because cholesterol and the cholate in the bile in the food can generate carcinogenic compound in intestinal, these chemical compounds can stimulate intestinal mucosa as overstand in intestinal, bring out colorectal cancer.Constipation also can be upset the large intestine mechanism of qi, and abdominal pressure is raise, and causes anal and intestinal diseases such as bleeding hemorrhoids, anal fissure, and patients with hypertension also can bring out apoplexy, and people's body and mind of constipation that hence one can see that is painful.Therefore, the successive dynasties expert in health preserving attaches great importance to the maintenance free movement of the bowels, promotes the metabolism of human body.The famous expert in health preserving king in Han dynasty fills the health preserving proposition that has proposed to have much insight: " wish to get long-living, Chang Qing in the intestinal wishes to get not deadly, does not have slag in the intestinal.”
The medicine of well-known treatment constipation is a lot, have chemosynthesis Western medicine, the instrument of physical method arranged, also diversiform Chinese medicine arranged.Make a general survey of various types of products, its certain effect is all arranged, the phenolphthalein of chemical classes for example, it can urgently solve defecation, but life-time service has side effect.Instrument treatment is more time-consuming also limitation, and then often dose is bigger for Chinese medicine, though Chinese medicine that has such as cathartic effect are better, taking for a long time also has side effect.Changshuning capsule of the present invention is that Semen Pruni, the Fructus Cannabis of the medicine food dual-purpose announced with health ministry is primary raw material, is equipped with also edible Aloe powder, is made into capsule jointly, and defecation significantly has no side effect, and is subjected to the welcome of vast constipation patient deeply.We do following introduction for above-mentioned three flavor raw materials:
Semen Pruni: the Chinese Pharmacopoeia record, this product is moisturized laxation, the therapeutic method to keep the adverse QI flowing downwards, diuretic.Be used for intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.The record of Chinese medicine voluminous dictionary, strongly fragrant Lee's seed contains amygdalin, fatty oil 58.3~74.2%, and is controlling the wind heat constipation due to disorder of QI, and puerperal, the intestines and stomach was scorching, and big constipation is puckery, controls the dyspnea with rapid and short breath of beriberi generalized edema with distention of the chest and abdomen, all uses the Semen Pruni prescription when defecation is puckery.The Ministry of Public Health regulation is as the thing of medicine food dual-purpose.
Fructus Cannabis: the Chinese Pharmacopoeia record, this product loosening bowel to relieve constipation is used for blood deficiency and depleted fluid, the dryness of the intestine constipation.Chinese medicine voluminous dictionary record, the fatty oil of Fructus Cannabis is about 30%, wherein is mainly unsaturated fatty acid.And the report of controlling constipation arranged.Report in " medicine justice " " can go dry for Fructus Cannabis, energy intestine moistening, and the patent large intestine is depressed just to be closed by the body profit.Person in middle and old age's blood is uninteresting, and puerperal, QI and blood had some setbacks, and vigour is not multiple after being ill, or can not move all a little less than reporting and control.It is obstructed that large intestine closes knot, should not push away and swing, and also do not allow to close for a long time, and with this same Radix Asteris, Semen Armeniacae Amarum moistens its lung qi, grows its large intestine, then just diarrhea ", this product is also eaten the thing of dual-purpose for medicine.
Aloe: Chinese Pharmacopoeia record, Aloe removing heat from the liver, relieving constipation.Be used for constipation, infantile malnutrition, infantile convulsion; The external treatment exudative dermatitis, the record of Chinese medicine voluminous dictionary, the fresh juice of Aloe vulgaris contains the crystallization of Aloe Radix Et Rhizoma Rhei rope glycoside, P-coumaric acid, a small amount of phlorose, a kind of aldopentose, protein and many calcium oxalates.
Summary of the invention
The purpose of this invention is to provide a kind of Changshuning capsule and preparation method thereof.
Consisting of of Changshuning capsule: Semen Pruni: Fructus Cannabis: Aloe powder=1: 1~10: 0.1~0.2.
The preparation method of Changshuning capsule is that Semen Pruni, Fructus Cannabis are weighed in 1: 1~10 ratios, cleans, and adds 5~10 times of water gagings and decocts 1~2 hour, filter, get filtrate, so repeat 2~3 times, merging filtrate moves into baking oven after being concentrated into thick extractum, and 50~70 ℃ of bakings are done near, add 0.1~0.2 part of Aloe powder, stir, continue to move to baking oven, dry by the fire to moisture in 50~70 ℃ and to be lower than 3~5%, take out, be crushed to 60~80 orders, pour into capsule.
The present invention is safe and effective, and taking dose is little.
1, show through Zhejiang Academy of Medical Sciences health food institute (health ministry assigned food toxicology detects unit) toxicologic study:
1) acute toxicity: Changshuning capsule is to large and small Mus per os LD 50Male and female belong to non-toxic type all greater than the 20g/kg body weight.
2) micronucleus test: Changshuning capsule is negative to PCEMNR micronucleus test testing result.
3) the abnormal property of mouse sperm test: Changshuning capsule is negative to mouse sperm abnormal property test testing result.
4) Salmonella reversion test: Changshuning capsule Salmonella reversion test testing result is negative.
2, studies show that through Jiangsu Prov. Disease Preventing and Controlling Center's (health ministry assigned food health care detects unit) Changshuning capsule has the effect of loosening bowel to relieve constipation.The result is as follows:
1) intestinal propulsion test: the prepared Chinese ink propelling rate of middle and high dosage group is compared with the constipation model control group all and is improved, and wherein high dose group has significant difference (p<0.05).
2) defecation experiment: compare with the constipation model control group, low dose group 6h defecation grain increases, and has significant difference (p<0.05).
Show through clinical 30 routine human trials, take Changshuning capsule, once a day, each one to two, just can make constipation patient light defecation in 24 hours.Several exemplary are wherein arranged:
The male at 80 years old advanced age is arranged, suffer from senile constipation, take phenolphthalein, Folium Sennae for a long time, clothes back stool has loose bowels always shapeless, but also total worry has side effect.After change the clothes Changshuning capsule, two of every days, not only stool is shaped, and the stool color is also fine.With fearing to have side effect, how glad this old does not have indescribably.
Also have a middle-aged women of 45 years old, also suffer from habitual constipation, main by take * * * * capsule, every big 4, take for a long time and feel that also economic pressures are bigger, after use Changshuning capsule instead, two of every days, light in the same old way defecation, she is glad too.
The specific embodiment
Elaborate below in conjunction with embodiment.
Embodiment 1
Semen Pruni, Fructus Cannabis are weighed in 1: 1 ratio, clean, add 5 times of water gagings and decocted 1 hour, filter, get filtrate, so repeat 2 times, merging filtrate moves into baking oven after being concentrated into thick extractum, and 50 ℃ of bakings are done near, add 0.1 part of Aloe powder, stir, continue to move to baking oven, dry by the fire to moisture in 50 ℃ and to be lower than 3%, take out, be crushed to 60 orders, pour into capsule.
Embodiment 2
Semen Pruni, Fructus Cannabis are weighed in 1: 5 ratio, clean, add 10 times of water gagings and decocted 2 hours, filter, get filtrate, so repeat 3 times, merging filtrate moves into baking oven after being concentrated into thick extractum, and 70 ℃ of bakings are done near, add 0.2 part of Aloe powder, stir, continue to move to baking oven, dry by the fire to moisture in 70 ℃ and to be lower than 5%, take out, be crushed to 80 orders, pour into capsule.
Embodiment 3
Semen Pruni, Fructus Cannabis are weighed in 1: 10 ratio, clean, add 8 times of water gagings and decocted 2 hours, filter, get filtrate, so repeat 3 times, merging filtrate moves into baking oven after being concentrated into thick extractum, and 60 ℃ of bakings are done near, add 0.13 part of Aloe powder, stir, continue to move to baking oven, dry by the fire to moisture in 60 ℃ and to be lower than 5%, take out, be crushed to 60 orders, pour into capsule.

Claims (2)

1. a Changshuning capsule is characterized in that consisting of of it: Semen Pruni: Fructus Cannabis: Aloe powder=1: 1~10: 0.1~0.2.
2. the preparation method of a Changshuning capsule is characterized in that Semen Pruni, Fructus Cannabis are weighed in 1: 1~10 ratios, cleans, add 5~10 times of water gagings and decocted 1~2 hour, filter, get filtrate, so repeat 2~3 times, merging filtrate moves into baking oven after being concentrated into thick extractum, 50~70 ℃ of bakings are done near, add 0.1~0.2 part of Aloe powder, stir, continue to move to baking oven, dry by the fire to moisture in 50~70 ℃ and be lower than 3~5%, take out, be crushed to 60~80 orders, pour into capsule.
CNB02136219XA 2002-07-24 2002-07-24 Changshuning capsule and its prepn Expired - Fee Related CN1160111C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB02136219XA CN1160111C (en) 2002-07-24 2002-07-24 Changshuning capsule and its prepn

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Application Number Priority Date Filing Date Title
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CN1398629A true CN1398629A (en) 2003-02-26
CN1160111C CN1160111C (en) 2004-08-04

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623430B (en) * 2009-07-23 2011-01-05 尹光东 Traditional Chinese medicine for treating constipation by taking foot bath
CN102885912A (en) * 2011-07-20 2013-01-23 江西食方食坊中药食品有限公司 Shangxia beverage for relaxing bowels and preparation method thereof
CN103960710A (en) * 2014-03-19 2014-08-06 景颖 Health care soup for relieving gastrointestinal reactionafterchemotherapy of tumor patient as well as preparation method
CN104173499A (en) * 2013-05-24 2014-12-03 潘祖贤 Medicine treating constipation
CN105194176A (en) * 2015-10-16 2015-12-30 苏州神林堂中医药研究所 Defecation promoting capsule and preparation method thereof
CN105232884A (en) * 2015-09-28 2016-01-13 杨培刚 Traditional Chinese medicine composition for treating constipation
CN107183705A (en) * 2017-04-11 2017-09-22 凯泽(武汉)健康管理有限公司 A kind of relax bowel improves the functional food of constipation
CN108143894A (en) * 2018-03-09 2018-06-12 河南荟仁堂生物科技有限公司 A kind of aloe ease constipation capsule and preparation method thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101623430B (en) * 2009-07-23 2011-01-05 尹光东 Traditional Chinese medicine for treating constipation by taking foot bath
CN102885912A (en) * 2011-07-20 2013-01-23 江西食方食坊中药食品有限公司 Shangxia beverage for relaxing bowels and preparation method thereof
CN104173499A (en) * 2013-05-24 2014-12-03 潘祖贤 Medicine treating constipation
CN103960710A (en) * 2014-03-19 2014-08-06 景颖 Health care soup for relieving gastrointestinal reactionafterchemotherapy of tumor patient as well as preparation method
CN105232884A (en) * 2015-09-28 2016-01-13 杨培刚 Traditional Chinese medicine composition for treating constipation
CN105194176A (en) * 2015-10-16 2015-12-30 苏州神林堂中医药研究所 Defecation promoting capsule and preparation method thereof
CN107183705A (en) * 2017-04-11 2017-09-22 凯泽(武汉)健康管理有限公司 A kind of relax bowel improves the functional food of constipation
CN108143894A (en) * 2018-03-09 2018-06-12 河南荟仁堂生物科技有限公司 A kind of aloe ease constipation capsule and preparation method thereof

Also Published As

Publication number Publication date
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