CN1336958A - 来自谷氨酸棒杆菌的丙酮酸羧化酶 - Google Patents

来自谷氨酸棒杆菌的丙酮酸羧化酶 Download PDF

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Publication number
CN1336958A
CN1336958A CN98814374A CN98814374A CN1336958A CN 1336958 A CN1336958 A CN 1336958A CN 98814374 A CN98814374 A CN 98814374A CN 98814374 A CN98814374 A CN 98814374A CN 1336958 A CN1336958 A CN 1336958A
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China
Prior art keywords
ala
leu
val
sequence
pyruvate carboxylase
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Pending
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CN98814374A
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English (en)
Chinese (zh)
Inventor
A·J·辛斯基
P·A·莱萨德
L·B·威利斯
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Massachusetts Institute of Technology
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Massachusetts Institute of Technology
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Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of CN1336958A publication Critical patent/CN1336958A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01001—Pyruvate carboxylase (6.4.1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN98814374A 1998-12-23 1998-12-23 来自谷氨酸棒杆菌的丙酮酸羧化酶 Pending CN1336958A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/027301 WO2000039305A1 (en) 1998-12-23 1998-12-23 PYRUVATE CARBOXYLASE FROM $i(CORYNEBACTERIUM GLUTAMICUM)

Publications (1)

Publication Number Publication Date
CN1336958A true CN1336958A (zh) 2002-02-20

Family

ID=22268534

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98814374A Pending CN1336958A (zh) 1998-12-23 1998-12-23 来自谷氨酸棒杆菌的丙酮酸羧化酶

Country Status (9)

Country Link
EP (1) EP1147198A1 (ko)
JP (1) JP2003503006A (ko)
KR (1) KR20010112232A (ko)
CN (1) CN1336958A (ko)
AU (1) AU2203399A (ko)
BR (1) BR9816106A (ko)
CA (1) CA2356446A1 (ko)
MX (1) MXPA01006290A (ko)
WO (1) WO2000039305A1 (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103695454A (zh) * 2013-12-18 2014-04-02 山东寿光巨能金玉米开发有限公司 表达l-赖氨酸转运蛋白的重组质粒、工程菌及应用
CN105624175A (zh) * 2011-12-21 2016-06-01 Cj第一制糖株式会社 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法
CN110997703A (zh) * 2017-04-25 2020-04-10 汉阳大学校产学协力团 新丙酮酸转移酶

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2325598A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
DE60108144T2 (de) 2000-10-13 2005-06-02 Archer-Daniels-Midland Co., Decatur Rückkopplungfestes pyruvatcarboxylase gen aus corynebacterium
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
CN101573438B (zh) * 2006-09-15 2013-01-02 Cj第一制糖株式会社 具有增加的l-赖氨酸生产力的棒状杆菌和使用其生产l-赖氨酸的方法
KR100830826B1 (ko) 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
US8932861B2 (en) 2008-04-10 2015-01-13 Cj Cheiljedang Corporation Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism
KR101126041B1 (ko) 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
DE102008001874A1 (de) 2008-05-20 2009-11-26 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren
DE102008044768A1 (de) 2008-08-28 2010-03-04 Evonik Degussa Gmbh Verfahren zur Herstellung von organisch-chemischen Verbindungen unter Verwendung von verbesserten Stämmen der Familie Enterobacteriaceae
CN113755492B (zh) * 2020-07-20 2023-05-30 中国科学院天津工业生物技术研究所 丙酮酸羧化酶基因启动子的突变体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219600B (hu) * 1993-08-24 2001-05-28 Ajinomoto Co., Inc. Mutáns foszfo-enolpiruvát-karboxiláz, ennek génje, valamint eljárás aminosav előállítására
SK284235B6 (en) * 1997-10-04 2004-11-03 Forschungszentrum Juelich Gmbh Method for microbial production of amino acids of the aspartate and/or glutamate family and agents which can be used in the said method

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105624175A (zh) * 2011-12-21 2016-06-01 Cj第一制糖株式会社 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法
CN103695454A (zh) * 2013-12-18 2014-04-02 山东寿光巨能金玉米开发有限公司 表达l-赖氨酸转运蛋白的重组质粒、工程菌及应用
CN110997703A (zh) * 2017-04-25 2020-04-10 汉阳大学校产学协力团 新丙酮酸转移酶
CN110997703B (zh) * 2017-04-25 2023-05-19 汉阳大学校产学协力团 新丙酮酸转移酶

Also Published As

Publication number Publication date
BR9816106A (pt) 2001-09-11
JP2003503006A (ja) 2003-01-28
KR20010112232A (ko) 2001-12-20
AU2203399A (en) 2000-07-31
CA2356446A1 (en) 2000-07-06
EP1147198A1 (en) 2001-10-24
MXPA01006290A (es) 2002-04-17
WO2000039305A1 (en) 2000-07-06

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