CN1330323C - A topical bath lotion for treating gout and its preparation method - Google Patents
A topical bath lotion for treating gout and its preparation method Download PDFInfo
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Abstract
An external bath lotion for treating gout and a preparation method thereof, belonging to the field of health care medicines. The proportion and the preparation method are described in the specification. The invention provides the external bath lotion for treating gout diseases, which is practical, convenient, quick in curative effect, free from toxic and side effects, capable of clearing heat, activating blood circulation, eliminating stagnation, detoxifying, dispelling wind, removing dampness, dredging collaterals and relieving pain, by taking the traditional Chinese medicine theory as guidance and combining the traditional secret recipe and proved recipe with the modern science and technology and the daily chemical technology.
Description
Technical field
The present invention relates to health care medicine, specifically a kind ofly combine the externally applied bath liquid of making that is used for the treatment of gout with daily-use chemical industry bathing agent by extracts of Chinese herbal medicine.
Background technology
The gout of indication of the present invention is meant the disease that causes because of the purine metabolism obstacle.Patient's serum and urine uric acid salinity raise, by finger joints such as (toes), helix, kidney etc. are located, and the formation of accumulation of uric acid sodium salt crystal or calculus is arranged, and clinical manifestation is acute and chronic gouty arthritis, joint deformity, tophus, renal calculus and nephropathy.
Along with the raising gradually of people's living standard, in recent years, this sick sickness rate is continuous ascendant trend.In the ill crowd of primary disease, the 95%th, middle-aged male, female patient are that symptom is lighter in the sequela in menopause mostly.This disease is divided into asymptomatic stage, acute arthritis phase and chronic arthritis phase clinically, is similar to diseases such as " arthralgia aggravated by cold " in the traditional Chinese medical science arthromyodynia, " severe and migratory arthralgia ".
At present, in the treatment of gout, medicine commonly used all has bigger toxic and side effects as " colchicine " etc., during use, brings unnecessary misery to the patient.
Summary of the invention
An object of the present invention is to addressing the above problem, overcome the weak point of chemical drugs, reduce patient's misery, eliminate side effect, to people provide a kind of practicality, convenience, curative effect fast, have no side effect, the externally applied bath liquid of heat clearing and blood circulation promoting, powder detoxifcation, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain is arranged.
Another object of the present invention provides a kind of preparation method for the treatment of the externally applied bath liquid of gout.
For achieving the above object, a technical scheme of the present invention provides a kind of prescription for the treatment of the externally applied bath liquid of gout, and its percentage by weight is: sodium lauryl sulfate 10-25%, sodium chloride 1-3%, cocoanut oil diethan olamide 2-4%, Chinese medicine extraction liquid 65-80%.
Can also contain Methyl p-hydroxybenzoate alcoholic solution 0-0.2% in the external emulsion of the present invention, spice 0-0.2%.
The present invention treats the optimization formula of the externally applied bath liquid of gout: sodium lauryl sulfate 20%, sodium chloride 2%, cocoanut oil diethan olamide 3%, Chinese medicine extraction liquid 74.8%; Can also contain Methyl p-hydroxybenzoate alcoholic solution 0.1%, spice 0.1%.
Chinese medicine extraction liquid is made by the following material of weight portion: Radix Angelicae Sinensis 30-50 part, Olibanum 30-50 part, Myrrha 30-50 part, Rhizoma Chuanxiong 50-70 part, Radix Achyranthis Bidentatae 50-70 part, Zaocys 50-70 part, catechu 50-70 part, Flos Carthami 20-40 part, Lignum Sappan 80-120 part, Radix Dipsaci 80-120 part, Radix Saposhnikoviae 80-120 part, Rhizoma Cibotii 80-120 part, Radix Angelicae Pubescentis 80-120 part, Rhizoma Et Radix Notopterygii 80-120 part, Rhizoma Pinelliae 20-40 part, Caulis Spatholobi 80-120 part, Folium Artemisiae Argyi 20-40 part, Semen Strychni 15-25 part, Radix Et Rhizoma Rhei 20-40 part, Cortex erythrinae 20-40 part.
Optimization formula is: 40 parts of Radix Angelicae Sinensis, 40 parts of Olibanums, 40 parts of Myrrhas, 60 parts of Rhizoma Chuanxiongs, 60 parts of Radix Achyranthis Bidentataes, 60 parts of Zaocys, 60 parts in catechu, 30 parts on Flos Carthami, 100 parts of Lignum Sappans, 100 parts of Radix Dipsaci, 100 parts of Radix Saposhnikoviaes, 100 parts of Rhizoma Cibotii, 100 parts of Radix Angelicae Pubescentiss, 100 parts of Rhizoma Et Radix Notopterygiis, 30 parts of the Rhizoma Pinelliaes, 100 parts of Caulis Spatholobis, 30 parts of Folium Artemisiae Argyis, 20 parts of Semen Strychni, 30 parts of Radix Et Rhizoma Rhei, 30 parts of Cortex erythrinaes.
The effect of above-mentioned various medicines is as follows:
Radix Angelicae Sinensis: be the root of umbelliferae angelica.Nature and flavor: Gan Xin, temperature.Function cures mainly: benefiting blood and regulating blood circulation, menstruction regulating and pain relieving is moisturized laxation.
Olibanum: be the gum resin of olive subject plant Boswellia carterii Birdw.Nature and flavor: arduous, temperature.Function cures mainly: regulating qi and activating blood, analgesic therapy, detoxification.
Myrrha: be the gum resin of olive subject plant myrrh or Alan's fort myrrh.Nature and flavor: hardship, flat.Function cures mainly: the blood and dissolving stasis that looses, subduing swelling and relieving pain.
Rhizoma Chuanxiong: samphire Rhizoma Chuanxiong rhizome.Nature and flavor: suffering, temperature.Function cures mainly activating QI to alleviate the depression dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.
Radix Achyranthis Bidentatae: different name: Radix Achyranthis Bidentatae, chicken glue bone; Root for the amaranthaceous plant Radix Achyranthis Bidentatae; Function cures mainly: gives birth to the congestion that looses, subduing inflammation is ripe in invigorating the liver and kidney, bone and muscle strengthening.
Zaocys different name: the sword ridge crow tip, black Serpentis, blue or green Serpentis; Nature and flavor: sweet salty, flat; Function cures mainly: wind-damp dispelling, the meridian dredging.
Catechu: different name: Catechu, black father's mud, thank in the west; Fry in shallow oil juice for the branch and leaf of the branch of leguminous plant catechu or Maguireothamnus speciosus Uncaria gambier Roxb. and concentrate the powdered extract that forms.
Flos Carthami different name: red blue flower, thorn Flos Carthami; Nature and flavor: suffering, temperature; Function cures mainly: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.
Radix Saposhnikoviae: be the root of umbelliferae Saposhnikovia divaricata.Nature and flavor: Xin Gan, temperature.Function cures mainly: deliver, dispel the wind, win and wet, pain relieving.
Radix Angelicae Pubescentis: be the root and rhizome of the heavy peristome Radix Angelicae Sinensis of samphire, Angelica pubescens, Xingan's Radix Angelicae Dahuricae, purple stem Radix Angelicae Pubescentis, Radix Heraclei hemsleyani, fur Radix Angelicae Pubescentis and Araliaceae Shi Yong Cortex araliae chinensis etc.Nature and flavor: arduous, temperature; Function cures mainly: dispel the wind, win and wet, cold expelling, pain relieving.
Rhizoma Et Radix Notopterygii: the root and rhizome of samphire Rhizoma Et Radix Notopterygii, Radix et Rhizoma Notopterygii or angelica.Nature and flavor: arduous, temperature.Function cures mainly: the exterior cold of loosing, wind-damp dispelling, sharp joint.The wind and cold that cures cold, it is lossless to have a headache, anemofrigid-damp arthralgia, the stiffness of the nape muscular contracture, joint is ached, edema due to wind pathogen edema, skin sore.
Caulis Spatholobi: ratan such as leguminous plant spatholobus suberectus, Mucuna birdwoodiana, fragrant flower Moghania fluminalis(C. B. Clarke) Li rattan or bright leaf Moghania fluminalis(C. B. Clarke) Li rattan.Nature and flavor: bitter sweet, temperature.Function cures mainly: invigorate blood circulation, Shujin.Control soreness of waist and knee joint, paralysis and numbness, menoxenia.
Folium Artemisiae Argyi: be the dried leaves of feverfew Chinese mugwort, nature and flavor: toil, temperature; Function cures mainly: the blood of regulating the flow of vital energy, by cold-damp, warming the meridian for stopping bleeding, antiabortive.
Semen Strychni: different name: before vomiting nut, bitter real, the horse, Niu Yin, generous eight; Mature seed for the loganiaceae plant Semen Strychni; Nature and flavor: bitter, cold, poisonous; Function cures mainly: the heat in blood of loosing, reducing swelling and alleviating pain;
Radix Et Rhizoma Rhei: different name: yellow good, fire ginseng, skin are as, general, Radix Et Rhizoma Rhei; Be polygonum rheum palmatum, Rheum tanguticum or Rheum officinale rhizome; Nature and flavor: bitter, cold; Function cures mainly: the poison that purges heat, removing mass stagnate clots absorbing blood.
Cortex erythrinae: different name: CORTEX ERYTHRINAE, DINGPI, transfixation, showy reiolaena root-bark; Dried bark for the leguminous plant erythrina indica; Nature and flavor: toil, flat; Function cures mainly: wind-damp dispelling, the meridian dredging, parasite killing.
For achieving the above object, another technical scheme of the present invention provides a kind of preparation method that is used for the treatment of the externally applied bath liquid of gout, and this method may further comprise the steps:
(1) preparation of Chinese medicine extraction liquid: accurately take by weighing raw material, add 5000 parts of water, decocted 30 minutes, filter, filtering residue is added 5000 parts of water, be fried boiling 20 minutes, filter; The filtrate of secondary filter is mixed, be concentrated into 8000 parts;
(2) step (1) Chinese medicine extraction liquid is maintained the temperature at 45-55 ℃, constantly adding sodium lauryl sulfate, sodium chloride, cocoanut oil diethan olamide under the condition of stirring, dissolving evenly;
(3) can also in the material of step (2) preparation, add the alcoholic solution and the spice of methyl hydroxybenzoate;
(4) above-mentioned (2) or (3) solution are behind the prior art homogenizing, and the cooling cooling is a kind of externally applied bath liquid that is used for the treatment of gout of the present invention.
The methyl hydroxybenzoate alcoholic solution is 95% ethanol and methyl hydroxybenzoate according to 1-2: 1 ratio is formulated.
The present invention takes into account prevention and treatment, with motherland's theory of medicine is guidance, with traditional Chinese medicine balneotherapy, combine with modern science and technology and daily use chemicals technology, by the warm power of bath water and the effect of medicine itself, whole body space between skin and muscles mediation, hair key are opened, impel skin permeation of drugs, positions such as hole key, fertile cave are directly absorbed, enter passages through which vital energy circulates, blood network reach medication rapidly, administration puts in place, easy operating, effect evident in efficacy.Make the people among comfortable dipping bath, reach the effect of treatment.
The present invention routine patient surplus 70 is on probation, and effective percentage reaches 90%, has no side effect, and has obtained good effect.
Used 3-4 days, the patient is sick to send out the place hotness, swell, skin is perspired, QI-blood circulation is quickened, the pore diffusion, and making hides excretes in the wind of body shallow-layer, wet, cold, pathogen etc.Limbs tricks etc. are strong, and the state of an illness alleviates.90% rheumatisant's state of an illness begins to take a turn for the better.
Use a course of treatment, medicine gos deep into positions such as skeleton, muscle, kidney, and rapid permeability decomposes, and clears up harmful pathogenic bacteria in the body, by perspiration, defecation, keeps watch, wet, tremble with fear, evil reaching be harmful to pathogenic bacteria and excrete, and the patient has relaxation immediately.Limbs sufferer place improves obviously, and slight illness further alleviates, and regaining consciousness gradually in joint etc., lifts lower limb, and the function of cranking arm is obviously improved, and seriously ill patient lives and can take care of oneself substantially.
Use 2-3 the drug effect deep layer onset course of treatment, regulate the generation of purine homergy, inhibition uric acid, the drainage that promotes uric acid, dissolving gouty calculus, through sufferer places such as multinomial activation, reparation sclerotin, meridians and limbs, focus obtains comprehensively effectively treatment, symptom complete obiterations such as arthroncus, heat, pain, limb activity fully freely, it is accessible to take action, and to common complications such as hypertension, hyperlipidemia, obesity, diabetes, arteriosclerosis, the limited good curative effect of coronary heart disease.
During use, only need by this bath lotion and water with 1: the ratio of 5-10 joins this product in the 30-50 ℃ of warm water, carries out bathing, every day three times, each 30 minutes, eight days courses of treatment, can reach purpose of the present invention.
The specific embodiment
Enumerate embodiment below, the present invention is further specified, but the present invention is not only limited to these embodiment.
The preparation of embodiment 1 Chinese medicine extraction liquid
Accurately take by weighing Radix Angelicae Sinensis 40kg, Olibanum 40kg, Myrrha 40kg, Rhizoma Chuanxiong 60kg, Radix Achyranthis Bidentatae 60kg, Zaocys 60kg, catechu 60kg, Flos Carthami 30kg, Lignum Sappan 100kg, Radix Dipsaci 100kg, Radix Saposhnikoviae 100kg, Rhizoma Cibotii 100kg, Radix Angelicae Pubescentis 100kg, Rhizoma Et Radix Notopterygii 100kg, Rhizoma Pinelliae 30kg, Caulis Spatholobi 100kg, Folium Artemisiae Argyi 30kg, Semen Strychni 20kg, Radix Et Rhizoma Rhei 30kg, Cortex erythrinae 30kg by prescription, add 5000kg water, decocted 30 minutes, filter, filtering residue is added 5000kg water, be fried boiling 20 minutes, and filtered; The filtrate of secondary filter is mixed, be concentrated into 8000kg;
The preparation of embodiment 2 film former
The 74.8kg Chinese medicine extraction liquid is heated to 50 ℃, is constantly adding 20kg sodium lauryl sulfate, 2kg sodium chloride, 3kg cocoanut oil diethan olamide under the condition of stirring, dissolving evenly; The alcoholic solution 0.1kg jasmine flower essence that adds methyl hydroxybenzoate, behind the prior art homogenizing, the cooling cooling is a kind of externally applied bath liquid that is used for the treatment of gout of the present invention.
Embodiment 3-7
With same method preparation is used for the treatment of Chinese medicine preparation in the externally applied bath liquid of gout with embodiment 1, concrete material name and proportioning that embodiment 3-7 uses are as shown in table 1.
Table 1: concrete material name in the Chinese medicine preparation and proportioning (units)
| Material name | Embodiment 3 | Embodiment 4 | Embodiment 5 | Embodiment 6 | Embodiment 7 | |
| Chinese medicine extraction liquid | Radix Angelicae Sinensis | 30 | 50 | 35 | 45 | 40 |
| Olibanum | 30 | 50 | 35 | 45 | 40 | |
| Myrrha | 30 | 50 | 35 | 45 | 40 | |
| Rhizoma Chuanxiong | 50 | 70 | 65 | 60 | 55 | |
| Radix Achyranthis Bidentatae | 50 | 70 | 65 | 60 | 55 | |
| Zaocys | 50 | 70 | 65 | 60 | 55 | |
| Catechu | 50 | 70 | 65 | 60 | 55 | |
| Flos Carthami | 20 | 40 | 25 | 30 | 35 | |
| Lignum Sappan | 80 | 120 | 90 | 100 | 110 | |
| Radix Dipsaci | 80 | 120 | 110 | 100 | 90 | |
| Radix Saposhnikoviae | 80 | 120 | 100 | 110 | 90 | |
| Rhizoma Cibotii | 80 | 120 | 90 | 110 | 100 | |
| Radix Angelicae Pubescentis | 80 | 120 | 110 | 100 | 90 | |
| Rhizoma Et Radix Notopterygii | 80 | 120 | 100 | 90 | 110 | |
| The Rhizoma Pinelliae | 20 | 40 | 35 | 30 | 25 | |
| Caulis Spatholobi | 80 | 120 | 110 | 90 | 100 | |
| Folium Artemisiae Argyi | 20 | 40 | 25 | 35 | 30 | |
| Semen Strychni | 15 | 25 | 20 | 18 | 17 | |
| Radix Et Rhizoma Rhei | 20 | 40 | 35 | 30 | 25 | |
| Cortex erythrinae | 20 | 40 | 30 | 25 | 35 |
Embodiment 8-12
With preparing the externally applied bath liquid that is used for the treatment of gout with embodiment 2 same methods, concrete material name and proportioning that embodiment 8-12 uses are as shown in table 2.
Table 2: the concrete material name of externally applied bath liquid and proportioning (unit: kg)
| Embodiment 8 | Embodiment 9 | Embodiment 10 | Embodiment 11 | Embodiment 12 | |
| Sodium lauryl sulfate | 100 | 250 | 150 | 200 | 180 |
| Sodium chloride | 10 | 30 | 15 | 20 | 25 |
| Cocoanut oil diethan olamide | 20 | 40 | 25 | 30 | 35 |
| The Methyl p-hydroxybenzoate alcoholic solution | 0 | 2 | 1 | 1.5 | 0.5 |
| Spice | 1 | 2 | 0 | 0.5 | 1.5 |
| Chinese medicine extraction liquid | 869 | 676 | 809 | 748 | 758 |
Claims (7)
1, a kind of externally applied bath liquid for the treatment of gout, the externally applied bath liquid of this treatment gout is mainly made by the material of following percentage by weight: lauryl alcohol acid sodium 10-25%, sodium chloride 1-3%, cocoanut oil diethan olamide 2-4%, all the other are Chinese medicine extraction liquid; Described Chinese medicine extraction liquid is made by following bulk drugs: Radix Angelicae Sinensis 30-50 part, Olibanum 30-50 part, Myrrha 30-50 part, Rhizoma Chuanxiong 50-70 part, Radix Achyranthis Bidentatae 50-70 part, Zaocys 50-70 part.Catechu 50-70 part, Flos Carthami 20-40 part, Lignum Sappan 80-120 part, Radix Dipsaci 80-120 part, Radix Saposhnikoviae 80-120 part, Rhizoma Cibotii 80-120 part, Radix Angelicae Pubescentis 80-120 part, Rhizoma Et Radix Notopterygii 80-120 part, Rhizoma Pinelliae 20-40 part, Caulis Spatholobi 80-120 part, Folium Artemisiae Argyi 20-40 part, Semen Strychni 15-25 part, Radix Et Rhizoma Rhei 20-40 part, Cortex erythrinae 20-40 part.
2, the externally applied bath liquid of treatment gout according to claim 1 is characterized in that, the externally applied bath liquid of this treatment gout can also contain the following material of percentage by weight: 0-0.2% Methyl p-hydroxybenzoate alcoholic solution, 0-0.2% spice.
3, must ask 1 or the externally applied bath liquid of described treatment gout according to power, it is characterized in that: wherein the consumption of each component is a sodium lauryl sulfate 20%, sodium chloride 2%, cocoanut oil diethan olamide 3%, Chinese medicine extraction liquid 75%.
4, the externally applied bath liquid of treatment gout according to claim 1 and 2 is characterized in that, sodium lauryl sulfate 20%, sodium chloride 2%, cocoanut oil diethan olamide 3%, Chinese medicine extraction liquid 74.8%, Methyl p-hydroxybenzoate alcoholic solution 0.1%, spice 0.1%.
5, the externally applied bath liquid of treatment gout according to claim 1 and 2 is characterized in that: Chinese medicine extraction liquid is made by the following material of weight portion: 40 parts of Radix Angelicae Sinensis, 40 parts of Olibanums, 40 parts of Myrrhas, 60 parts of Rhizoma Chuanxiongs, 60 parts of Radix Achyranthis Bidentataes, 60 parts of Zaocys, 60 parts in catechu, 30 parts on Flos Carthami, 100 parts of Lignum Sappans, 100 parts of Radix Dipsaci, 100 parts of Radix Saposhnikoviaes, 100 parts of Rhizoma Cibotii, 100 parts of Radix Angelicae Pubescentiss, 100 parts of Rhizoma Et Radix Notopterygiis, 30 parts of the Rhizoma Pinelliaes, 100 parts of Caulis Spatholobis, 30 parts of Folium Artemisiae Argyis, 20 parts of Semen Strychni, 30 parts of Radix Et Rhizoma Rhei, 30 parts of Cortex erythrinaes.
6, the preparation method of the externally applied bath liquid of treatment gout according to claim 1 is characterized in that, the step of this method is as follows:
(1) preparation of Chinese medicine extraction liquid: accurately take by weighing raw material, add 5000 parts of water, decocted 30 minutes, filter, filtering residue is added 5000 parts of water, be fried boiling 20 minutes, filter; Secondary filter liquid is mixed, be concentrated into 8000 parts;
(2) step (1) Chinese medicine extraction liquid is maintained the temperature at 50 ℃, constantly adding and sodium lauryl sulfate, sodium chloride, cocoanut oil diethan olamide under the condition of stirring, dissolving evenly;
(3) above-mentioned (2) solution is behind the prior art homogenizing, and the cooling cooling is a kind of externally applied bath liquid that is used for the treatment of gout of the present invention.
7, the preparation method of the externally applied bath liquid of treatment gout according to claim 6 is characterized in that, can also add the alcoholic solution and the spice of methyl hydroxybenzoate in the material of step (2) preparation.
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| CNB2005100681916A CN1330323C (en) | 2005-04-29 | 2005-04-29 | A topical bath lotion for treating gout and its preparation method |
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| CN108096549A (en) * | 2017-12-29 | 2018-06-01 | 李汝清 | A kind of herbal fumigation agent for treating gout and its application method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1192916A (en) * | 1997-03-12 | 1998-09-16 | 李航海 | Chinese medicine for treatment of gout |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1192916A (en) * | 1997-03-12 | 1998-09-16 | 李航海 | Chinese medicine for treatment of gout |
Non-Patent Citations (1)
| Title |
|---|
| 中医药治疗痛风的研究概况 宋文冲 陈超，新中医，第35卷第7期 2003 * |
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