CN1327788C - Health-care food - Google Patents
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- CN1327788C CN1327788C CNB02157491XA CN02157491A CN1327788C CN 1327788 C CN1327788 C CN 1327788C CN B02157491X A CNB02157491X A CN B02157491XA CN 02157491 A CN02157491 A CN 02157491A CN 1327788 C CN1327788 C CN 1327788C
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Abstract
An object of the present invention is to provide a very effective health food for supplying a pungent substance, a bitter substance or a sour substance, in particular a pungent substance, thereby refreshing a body or feeling, preventing forgetting, and intensifying weakened muscles whereby the health food is useful in treating rheumatism, etc. The present invention relates to a health food product comprising a pungent, bitter and/or sour substance, especially to a health food product comprising at least an effective amount of pungent substances.
Description
Invention field
The present invention relates to new healthy food.
Background technology
Will in the brain substantial is that spirit substantial is called the thrombocytin of brain hormone, the control of norepinephrine, corresponding to enriching of this will, voluntary muscle is activated by the adrenaline that belongs to the adrenal medella class by the secretion of the chromaffin cell on adrenal medella and the neural flesh.
Thrombocytin, norepinephrine, adrenaline are called biological monoamine, and they were known as the oxydasis decomposition of monoamine oxidase in the longest 3 hours or by absorptions again such as nerve fibers, secreted nearly all monoamine can be ineffective.
This is because the monoamine long duration of action causes fatigue, is that human body prevents tired exquisite mechanism.
The morbidity of depressive illness causes lacking will owing to these biological monoamine secretion capacities descend and spirit is enriched, depressive state is maintained and causes, spirit goes down sometimes, until producing strong suicide hope.
So far, for the disposal of depressive illness, adopt passive heteropathy always, promptly, take the healthy food that suppresses the monoamine oxidase effect or prevent the resorbent healthy food of these monoamines, the concentration of the monoamine of these that keep that secretion capacity descends prevents that spirit is extremely dispirited.
But because this therapy is not to be the primal therapy of purpose to eliminate biological monoamine secretion capacity this pathogenic factor that descends, so it is a kind of therapy that can only expect that in heteropathy process over a long time monoamine secretion capacity can nature recovers.
But there is following shortcoming in this therapy: because monoamine always exists, the above-mentioned recovery naturally not only can further be weakened the monoamine secretion capacity, and causes easily by adrenaline sugar and lipid surplus are burnt and the physically-draining that fatigue produced that causes.
, gas is meant the function that human body is total, and this function roughly is divided into 2 kinds.The first is subjected to the function of autonomic nerve domination, is the function that each internal organs, hormone secretion, blood vessel etc. have.Another kind is the function of brain thinking, is to think deeply the instruction of sending and the function of the voluntary muscle that moves etc. by brain.
In traditional Chinese medicine, point out for a long time, by Fill gas, the gas that showed of regulating the flow of vital energy only is meant the function of the former autonomic nerve domination.The instruction how which function in these is brought into play is that the oblongata from the foot that is positioned at brain sends.Examine and consider Fill gas medicine and not only activate certain specific internal organs and organ, and activate the function of all autonomic nerve dominations, so, can think that the application point of Fill gas medicine is not each internal organs and organ, but the oblongata in its instruction generation source.That is, the effect of Fill gas medicine is to strengthen command signal and its transmission of promotion of sending from oblongata.The present inventor finds that Fill gas medicine concentrates in internal organs etc. the body inner blood, this also is by making vessel retraction, dilating effect performance function as one of oblongata important function, making the blood vessel dilatation of leading to the autonomic nerve dominating system and the vessel retraction of leading to brain and brain dominating system organ is realized, its objective is the secondary role of Zuo Wei Fill gas medicine, more nutrient is transported to the part that needs.
In the past, depressive illness is less generation, but in recent years, the depressive illness incidence of disease of countries in the world increases year by year, it is said that per 150 philtrums just have 1 depressive illness patient in Tokyo.
Recently, for the reason that this depressive illness incidence of disease increases, the someone has delivered a very interesting opinion.
That is, it is a kind of like this saying: remove a part of region dispute, the world is away from war danger, and civil order also obtains rectifying, and the chance that meets with an accident has also reduced, and human body performs the needs of dealing with dangerous spirit preparation not to have been had substantially yet.
For this reason, the needs of biogenic amine secretion also extremely reduce, and its secretion capacity is degenerated, and its result is easy to produce depressive illness.
If the words that this saying is correct, if then adopt the artificial means that promote biological monoamine secretion, for example 1 day 1 time, just can prevent the morbidity of depressive illness, the depressive illness patient that the biogenic amine secretion capacity is descended recovers the secretion capacity of biological monoamine, and the possibility of depressive illness recovery from illness also can produce.
Have again, along with the age constantly increases, prolapse of the anus and pin, waist, arm pain can appear, this just is understood that it is because in these parts always, blood circulation disorder or resultant inflammation cause, if be commonly used for certain medicine of getting rid of blood circulation disorder with being entirely separately, then the improvement of these illnesss is insufficient.
The reason of these obstacles is owing to brain instruction transmits insufficient causing to the part, because the incomplete transmission of brain instruction, the generation of blood circulation disorder and inflammation is the problem that can not proper motion produces owing to muscle.
Though all muscular disorders are not only insufficient the causing of transmission of brain instruction, it is generally acknowledged that the major part of this obstacle is the insufficient of brain instruction transmission.Find with advancing age that particularly the muscular disorders such as pain of produced simultaneously Low Back Pain, four limbs are easy to by improving the eliminatings such as curcumin that the brain instruction transmits.
The present invention is based on this new theory of medicine, carried out the exploitation of medicine, purpose is to provide has extremely effectively medicine of the action of muscles of enhancing, anti-inflammatory effect.
The present invention is based on this new theory of medicine, carried out the exploitation of healthy food, purpose is at depressive illness etc., provides extremely effectively healthy food to the people of off color.
Summary of the invention
The present invention relates to spicy substance, bitter substance or sour odour material, particularly contain the healthy food of spicy substance, bitter substance or the sour odour material of food.
Spicy substance of the present invention, bitter substance or sour odour material be spicy substance preferably.
Spicy substance is the curcumin of root tuber of aromatic turmeric preferably
[changing 1]
The capsicim of capsicum
[changing 2]
The pipering of pepper
[changing 3]
The zingerone of ginger
[changing 4]
[6]-salad oil of ginger
[changing 5]
[6]-gingerol of ginger
[changing 6]
Preferred especially curcumin.
As bitter substance, preferred swertiamarin, gentiamarin, loganin.
Sour odour material optimization citric acid, lactic acid.
One daily intake of spicy substance is 1-1000mg preferably, is 10-300mg better, is preferably 20-70mg.
Daily intake when they use separately is good with 100-800mg, is preferably 300-500mg.
In addition, when having the Chinese medicine preparation of the effect set upright with Shiquan Dabu Tang etc. or the daily intake of Chinese medicine and time spent is preferably 100-200mg.
As long as it is just passable that the present invention contains spicy substance, bitter substance or sour odour material; but be preferably; contain isoflavones, acyl group isoflavones and isoflavone glucoside, isoflavones, acyl group isoflavones and isoflavone glucoside be contained isoflavones, acyl group isoflavones and soybean isoflavone glucoside in the soybean preferably.
The acyl group of acyl group isoflavones is good with the sour residue of the saturated or unrighted acid of 2-18 carbon atom, preferably acetate, palmitic acid, stearic sour residue.In addition, acidylate can be with the whole acidylates of the hydroxyl of isoflavones, also can be with one part of hydroxyl acidylate.
Owing to can increase oil-soluble by acidylate, therefore, be under the situation of finish at preparation, can dissolve a large amount of acyl group isoflavones.
The preferred 1-500mg of one daily intake of isoflavones, acyl group isoflavones and isoflavone glucoside, more preferably 5-200mg, especially preferably 10-100mg.
The preferred 1-1000mg of one daily dose of cholic acid, more preferably 2-300mg, especially preferably 10-100mg.
As long as it is just passable that the present invention contains spicy substance, bitter thing material or sour odour material; but be preferably; contain cholic acid and/or scymnol and/or scymnol ester, preferably contain cholic acid and/or scymnol and/or scymnol ester and isoflavones and/or acyl group isoflavones and/or isoflavone glucoside.
In addition, when using isoflavones, acyl group isoflavones and isoflavone glucoside, preferably add cholic acid.
The preferred 1-1000mg of one daily dose of cholic acid, more preferably 2-300mg, especially preferably 10-100mg.
The preferred 0.1-100mg of one daily intake of scymnol and/or scymnol ester, more preferably 0.1-50mg, especially preferably 0.3-10mg.
As other composition, use common healthy food, use vitamins, heme iron, plum extract, crude drug etc.
As crude drug, preferably have the effect set upright, for example, can activate crude drug and the digestive crude drug of the function of the organ that is subjected to the autonomic nerve domination, gland, blood vessel.
The known crude drug that can activate the function of the organ that is subjected to the autonomic nerve domination, gland, blood vessel has more than 10 kinds, for example, genseng etc. is arranged, and is that several active ingredients of these crude drugs of representative are understood with the genseng.
Therefore, preferably add these active ingredients.By these active ingredients of further interpolation, can bring into play the function of human body activation.
As such crude drug, special preferably ginseng, Radix Codonopsis, radix pseudostellariae, American Ginseng, the Radix Astragali, the bighead atractylodes rhizome, Chinese yam, Radix Glycyrrhizae, date, glue maltosemalt sugar, sealwort, lance asiabell root etc.
In addition, preferably add digestive crude drug, as hawthorn, Divine Comedy, radish seed, Fructus Hordei Germinatus, rice sprout, the membrane of a chicken's gizzard, asafoetide etc.
Scymnol and/or scymnol ester are included in the bile of shark.
Scymnol is represented by following structural formula.
In addition, scymnol sulfuric ester sodium salt is represented by following structural formula.
In addition, a kind of raw material that also has that uses in the present invention is isoflavones, acyl group isoflavones and isoflavone glucoside.
The contained active ingredient that meets this purpose is several isoflavones such as daidzein, Glycitein (glycitein), genistein of several isoflavone glucosides such as daidzin, Glycitein glycosides (glycitin), genistin or its aglycone in the soybean.
Soybean is a raw material of making soybean oil, and the requirement of soybean oil is big, and its by-product of soybean dregs of rice are also a large amount of simultaneously to be produced.Though the part of big dregs of beans is used as the manufacturing raw material of soybean protein (a kind of raw-food material), mainly as fertilizer, feed, its price is extremely low.With the big dregs of beans that is similar to trade waste is raw material, can high-purity and make isoflavones, acyl group isoflavones and soybean isoflavone glucoside at an easy rate.
Healthy food of the present invention can be with common pulvis, solid agent and liquor picked-up, and the material as mixing can use lactose, starch, plant wet goods.
Embodiment
Specify the present invention below.
The purity of the isoflavones that uses, acyl group isoflavones, soybean isoflavone glucoside is 40%.
Except pure product, the purity of the cholic acid of use is 90%.
Embodiment 1
Powder
Curcumin 45mg
Scymnol 1mg
Isoflavones 125mg
Lactose 800mg
Cornstarch is an amount of
Dolomol 10mg
Add up to 2000mg
(1 bag 1g, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make powder.
Embodiment 2
Granule
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Lactose 1500mg
Cornstarch is an amount of
Dolomol 10mg
Add up to 2000mg
(1 bag 1g, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make granule.
Embodiment 3
Tablet
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Avicel cellulose is an amount of
Lactose 140mg
Dolomol 6mg
Talcum powder 3mg
Add up to 1120mg
(1 280mg, 1 time 2,1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make tablet.
Embodiment 4
Tablet
Curcumin 45mg
Scymnol 1mg
Isoflavones 250mg
Genseng end 2000mg
Lactose 886mg
Avicel cellulose is an amount of
Calcium carboxymethylcellulose 320mg
Hydroxy propyl cellulose 558mg
Carplex
(trade name, a kind of synthetic silica, the wild 30mg of Japanese salt
Justice Pharmaceutical Co., Ltd product)
Dolomol 55mg
Add up to 5600mg
(1 280mg, 1 time 5,1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make tablet.
Embodiment 5
Hard shell capsules
Curcumin 45mg
Scymnol 1mg
Isoflavones 125mg
Lactose 218mg
Cornstarch is an amount of
Dolomol 6mg
Add up to 1150mg
(No. 1 capsule/4 capsule, 12 capsule, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make hard shell capsules.
Embodiment 6
Soft capsule
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Cod-liver oil 80mg
Tocopherol acetate 5mg
Ginseng extract 200mg
Beeswax 55mg
Appropriate amount of edible oil
Add up to 1200mg
(1 day 4 capsule)
Similarly, can use acyl group isoflavones, soybean isoflavone glucoside to replace isoflavones to make soft capsule.
Embodiment 7
Potus
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Korean ginseng extract 10mg
Glutinous rehmannia extract 10mg
Royal jelly 100mg
The plain 10mg of thiamine mononitrate
Riboflavine sodium phosphate 5mg
Pyridoxine Hydrochloride 10mg
Caffeine Anhydrous 50mg
Ethanol 1.2mL
Ethyl-para-hydroxybenzoate 4mg
Distilled water is an amount of
Add up to the 50mL/ bottle
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make potus.
Embodiment 8
Vitamin compatibility (hard shell capsules)
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Thiamine hydrochloride 25mg
Pyridoxine Hydrochloride 10mg
Riboflavin 10mg
Cobalamin 12 μ g
Niacinamide 20mg
Calcium pantothenate 20mg
Ascorbic acid 60mg
L-NAC 10mg
Lactose 263mg
Dolomol 6mg
Cornstarch is an amount of
Add up to 1150mg
(1 2 capsule, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make hard shell capsules.
Embodiment 9
Powder
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Cornstarch is an amount of
Light anhydrous silicic acid 5mg
Dolomol 10mg
Add up to 4000mg
(1 bag 2g, 1 day 2 times)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make powder.
Embodiment 10
Granule
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Cornstarch 800mg
Avicel cellulose 300mg
Light anhydrous silicic acid 5mg
Dolomol 10mg
Add up to 4000mg
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make granule.
Embodiment 11
Spheric granules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 515mg
Cornstarch is an amount of
Cold plum powder 500mg
Avicel cellulose 400mg
Add up to 2000mg
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make spheric granules.
Embodiment 12
Tablet
Curcumin 45mg
Cholic acid 140mg
Soybean isoflavone glucoside 280mg
Lactose 4000mg
Calcium carboxymethylcellulose 320mg
Hydroxypropyl cellulose 74mg
Avicel cellulose is an amount of
Carplex
30mg
Dolomol 10mg
Add up to 5484mg
(1 280g, 1 time 5,1 day 2 times)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make tablet.
Embodiment 13
Hard shell capsules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Cornstarch is an amount of
Dolomol 9mg
Add up to 1153mg
(No. 1 capsule 1 day 4)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make hard shell capsules.
Embodiment 14
Soft capsule
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Beeswax 55mg
Appropriate amount of edible oil
Add up to 1200mg
(1 day 4 capsule)
Similarly, can use isoflavones, acyl group isoflavones to replace soybean isoflavone glucoside to make soft capsule.
Embodiment 15
Potus
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Korean ginseng extract 1500mg
Longan extract 100mg
Fruit of Chinese magnoliavine liquid extract 300mg
Royal jelly 150mg
Riboflavine sodium phosphate 10mg
Ethanol 1.2ml
P-hydroxybenzoic acid 4mg
Distilled water is an amount of
Add up to 50ml
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make potus.
Embodiment 16
Granule
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Thiamine hydrochloride 10mg
Pyridoxine Hydrochloride 100mg
Hydrochloric acid hydroxycobalamin 1.027mg
Tocopherol acetate 100mg
Lactose 2700mg
Avicel cellulose 300mg
Light anhydrous silicic acid 5mg
Dolomol 10mg
Cornstarch is an amount of
Add up to 4000mg
(1 bag 2g, 1 day 2 times)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make granule.
Embodiment 17
Capsule
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Oleovitamin A 4mg
Cholecalciferol 0.005mg
Tocopherol acetate 10mg
Vitamin C 600mg
Avicel cellulose 250mg
Dolomol 6mg
Cornstarch is an amount of
Add up to 1150mg
(No. 1 capsule, 1 day 4)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make capsule.
Embodiment 18
Powder
Curcumin 30mg
Scymnol 1mg
Isoflavones 125mg
Lactose 800mg
Cornstarch is an amount of
Dolomol 10mg
Add up to 2000mg
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make powder.
Embodiment 19
Granule
Curcumin 30mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Lactose 1500mg
Cornstarch is an amount of
Dolomol 10mg
Add up to 2000mg
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make granule.
Embodiment 20
Tablet
Curcumin 25mg
Scymnol 1mg
Isoflavones 250mg
Genseng comes 2000mg
Lactose 886mg
Avicel cellulose is an amount of
Calcium carboxymethylcellulose 320mg
Hydroxypropyl cellulose 558mg
Carplex
30mg
Dolomol 55mg
Add up to 5600mg
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make tablet.
Embodiment 21
Soft capsule
Curcumin 25mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Cod-liver oil 80mg
Tocopherol acetate 5mg
Ginseng extract 200mg
Beeswax 55mg
Appropriate amount of edible oil
Add up to 1200mg
Similarly, can use acyl group isoflavones, soybean isoflavone glucoside to replace isoflavones to make soft capsule.
Embodiment 22
Potus
Curcumin 30mg
Scymnol sodium sulfovinate 1mg
Isoflavones 125mg
Korean ginseng extract 10mg
Glutinous rehmannia extract 10mg
Royal jelly 100mg
The plain 10mg of thiamine mononitrate
Riboflavine sodium phosphate 5mg
Pyridoxine hydrochloride 10mg
Caffeine Anhydrous 50mg
Ethanol 1.2L
Ethyl-para-hydroxybenzoate 4mg
Distilled water is an amount of
Add up to the 50mL/ bottle
Similarly, can use soybean isoflavone glucoside to replace isoflavones to make potus.
Embodiment 23
Powder
Curcumin 30mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Cornstarch is an amount of
Light anhydrous silicic acid 5mg
Dolomol 10mg
Add up to 4000mg
(1 bag 2g, 1 day 2 times)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make powder.
Embodiment 24
Granule
Curcumin 25mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Cornstarch is an amount of
Avicel cellulose 300mg
Light anhydrous silicic acid 5mg
Dolomol 10mg
Add up to 4000mg
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make granule.
Embodiment 25
Tablet
Curcumin 30mg
Cholic acid 140mg
Soybean isoflavone glucoside 280mg
Lactose 4000mg
Calcium carboxymethylcellulose 320mg
Hydroxypropyl cellulose 74mg
Avicel cellulose is an amount of
Carplex
30mg
Dolomol 10mg
Add up to 5484mg
(1 280mg, 1 time 5,1 day 2 times)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make tablet.
Embodiment 26
Hard shell capsules
Curcumin 25mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Cornstarch is an amount of
Dolomol 9mg
Add up to 1153mg
(No. 1 capsule, 1 day 4)
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make hard shell capsules.
Embodiment 27
Potus
Curcumin 30mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Korean ginseng extract 1500mg
Longan extract 100mg
Fruit of Chinese magnoliavine liquid extract 300mg
Royal jelly 150mg
Riboflavine sodium phosphate 10mg
Ethanol 1.2ml
P-hydroxybenzoic acid 4mg
Distilled water is an amount of
Add up to 50ml
Similarly, can use isoflavones to replace soybean isoflavone glucoside to make potus.
Though do not carry out the research of the adrenaline secretion facilitation of relevant curcumin, zingerone, salad oil, in the zoopery of using mouse, concentration of glucose significantly rises in the blood, can confirm the existence of adrenaline secretion facilitation thus.
Allow 10 people of preparation of China commonly used take following medicine continuously: 3 in the lactose tablet (every 250mg) 1 day that contains 15mg curcumin, 20mg cholic acid, 40mg soybean isoflavone glucoside with the effect set upright, curcumin every day 1 time, each 45mg the results are shown in the following table.
Table 1
| Age | Sex | Symptom | Medicine commonly used | The history of being in hospital | Effect | |||
| Antidepressant | The spirit stabilizing agent | The sleep medicine | ||||||
| 1 | 51 | The man | Serious depression, uneasiness | ○ | ○ | ○ | ○ | ◎ |
| 2 | 38 | The man | Insomnia, uneasiness, impatience | ○ | ○ | ○ | ○ | ○ |
| 3 | 51 | The man | Insomnia, uneasiness | × | × | × | × | - |
| 4 | 30 | The woman | Insomnia, uneasiness, depression | ○ | ○ | ○ | × | ◎ |
| 5 | 18 | The woman | Insomnia, uneasiness, impatience | × | × | × | × | ◎ |
| 6 | 76 | The man | Impatient | × | × | × | × | ○ |
| 7 | 74 | The woman | Strong uneasy, insomnia, impatience | × | × | × | × | ○ |
| 8 | 48 | The woman | Depression, sleep more | ○ | ○ | × | × | ◎ |
| 9 | 48 | The man | Be intended to go down impatience, major depression | × | × | × | × | ◎ |
| 10 | 39 | The woman | Major depression, insomnia, uneasiness | × | × | × | × | ◎ |
※ patient is diagnosed as depressive illness by medical practitioner
※ is about effect, and zero: effectively, ◎: significantly ,-: under observation
As above shown in the table, efficient is 90%, and the produce effects example reaches 60%.
According to this result, demonstrate the good result who it is generally acknowledged that the depressive illness that can not cure can be fully recovered.
Example shown in the table is back 2 months result of beginning that takes medicine, depressive illness has or not that sending out still needs again wants long-term observation, but the fact is, the user of many curcumins has returned to the state that can cross substantially near normal person's daily life, this proof, healthy food of the present invention is extremely effective as making refreshed food.After the 250mg lactose tablet administration that contains 1mg scymnol sodium sulfovinate (replacement cholic acid), can obtain same result.
In addition, give to show granule by the climacteric worry that causes of obstacle, depressed mood, illness such as dizzy 12 and 14 women's administration embodiment 2 and embodiment 10, as curcumin, administration every day 45mg, took back 5 days, 5 and 6 worries, depressed mood, dizzy improving are arranged respectively.In addition, after 3 weeks, add up to 11 and 12 to improve respectively.
In addition, give the granule of 10 patient's administration embodiment 2 of often forgetful senile dementia last stage, 7 forgetful improving behind the granule of administration embodiment 10, can obtain same result.In addition, also effective for Alzheimer's disease.
Anti-climacteric obstacle agent of the present invention, anti-senile dementia agent, anti-Alzheimer's disease agent have proved that the curative as treatment climacteric obstacle, senile dementia, Alzheimer's disease is extremely effective.
For curcumin, commercially available have a highly purified curcumin, is easy to obtain.
Take capsule 1 day 1 time for the depressive illness patient, this capsule is by 50mg capsicim and lactose are doubly loose, and and isoflavone glucoside carry out capsule with cholic acid and fill and make.
After a few days, effect is theatrical to be manifested, and has roughly broken away from depressive state after 1 week.
In addition, the capsicim pungent is strong.
Take the tablet 1 day 1 time of embodiment 20.
Thus, along with the age increases, 83 years old male sex walking easily of step property difficulty, prolapse of the anus severity has also broken away from prolapse of the anus, can oneself feel the action of anal sphincter clearly, by 1 month try out, obviously improve, and 63 years old male sex of stair activity difficulty be stair activity like a cork, by 1 month try out, obviously improve.In addition, the tablet of embodiment 25 also has same effect.
If these results only are the such pharmacological effects of the improvement of local muscle activity, in the result in the America and Europe who uses curcumin and Okinawa, should comprise such information, but unprecedented, this is because the brain instruction that the result of brain thinking sends causes to local transmission is undesired.
In doctor trained in Western medicine, though it is to be caused by these local blood circulation disorders and its resultant inflammation that the pain of prolapse of the anus and pin, waist, arm can only be interpreted as, but use separately when having cooperated scymnol with the effect of abundant eliminating blood circulation disorder, isoflavones, cholic acid, because it is insufficient to improve these symptom, the reason of these obstacles can be understood as because brain instruction causes to local transmission is insufficient, the generation of blood circulation disorder and inflammation is that the incomplete transmission owing to brain instruction makes the muscle can not regular event, so produced obstacle.
In addition, take for each 5 patient of men and women in 60-75 year of muscular disorders such as telling the pain in the back that produces with advancing age, brothers' pain, prolapse of the anus after, these symptom improve.Muscular disorders generally speaking is not insufficient the causing of brain instruction transmission, and transmission is insufficient but the major part of this obstacle is the brain instruction.
The merging of isoflavones, cholic acid, scymnol, curcumin etc. is used owing to have the effect that improves cerebration, can remove muscular disorders, concerning the advanced age person, can be one and seek and good news that spirit, muscle power youthen together.In addition, this prescription has remarkable result for arthritis such as rheumatism, particularly performance effect greatly in prevention.
For curcumin, commercially available highly purified curcumin is arranged, be easy to obtain.
Use the 30mg capsicim to replace the curcumin of embodiment 18,, take for the person at advanced age of 76 years old and 83 years old by 1 administration in 1 day.After a few days, effect is theatrical to be manifested, after 1 week, effective to muscle deterioration, arthritis, rheumatism etc.
The present invention has can provide healthy food such excellent results by picked-up spicy substance, bitter substance or sour odour material, and this healthy food makes refreshed, prevent forgetful, strengthen the muscle of degenerating, be effective for rheumatism etc.
Claims (10)
1. health food composition; it is characterized in that; contain spicy substance, bitter substance or sour odour material; and contain (i) cholic acid and/or scymnol and/or scymnol ester and (ii) isoflavones and/or acyl group isoflavones and/or isoflavone glucoside; described spicy substance is selected from curcumin, capsicim, pipering, zingerone, [6]-salad oil, [6]-gingerol; described bitter substance is selected from swertiamarin, gentiamarin, loganin, and described sour odour material is selected from citric acid, lactic acid.
2. health food composition according to claim 1 is characterized in that described spicy substance, bitter substance or sour odour material are food.
3. health food composition according to claim 1 is characterized in that described spicy substance, bitter substance or sour odour material are spicy substances.
4. health food composition according to claim 1 is characterized in that described spicy substance is a curcumin.
5. health food composition according to claim 1 is characterized in that, described isoflavones, acyl group isoflavones and isoflavone glucoside are isoflavones, acyl group isoflavones and soybean isoflavone glucoside.
6. health food composition according to claim 1 is characterized in that, has added vitamin preparation.
7. health food composition according to claim 1 is characterized in that, has added crude drug.
8. health food composition according to claim 7 is characterized in that described crude drug has the effect of setting upright.
9. health food composition according to claim 8 is characterized in that, described crude drug is more than one in genseng, Radix Codonopsis, radix pseudostellariae, American Ginseng, the Radix Astragali, the bighead atractylodes rhizome, Chinese yam, Radix Glycyrrhizae, date, glue maltosemalt sugar, sealwort, the lance asiabell root.
10. health food composition according to claim 8 is characterized in that, described crude drug is more than one in hawthorn, Divine Comedy, radish seed, Fructus Hordei Germinatus, rice sprout, the membrane of a chicken's gizzard, the asafoetide.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001384860 | 2001-12-18 | ||
| JP2001384860 | 2001-12-18 | ||
| JP200242639 | 2002-02-20 | ||
| JP2002042639A JP4609875B2 (en) | 2001-07-31 | 2002-02-20 | healthy food |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1429498A CN1429498A (en) | 2003-07-16 |
| CN1327788C true CN1327788C (en) | 2007-07-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB02157491XA Expired - Fee Related CN1327788C (en) | 2001-12-18 | 2002-12-18 | Health-care food |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US10918685B2 (en) * | 2017-01-05 | 2021-02-16 | Ravi Ramamoorthy Iyer | Herbal topical composition for muscle and joint health, recovery from exertion, and for pain management |
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| JPH07138277A (en) * | 1993-11-17 | 1995-05-30 | Pola Chem Ind Inc | Production of scymnol sulfate |
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| JPH1146719A (en) * | 1997-08-04 | 1999-02-23 | Snow Brand Milk Prod Co Ltd | Nutrition composition |
| CN1273788A (en) * | 1999-05-15 | 2000-11-22 | 马锡洪 | Snack series |
| CN1302559A (en) * | 1999-11-26 | 2001-07-11 | Basf公司 | Curcumin preparation |
| CN1323544A (en) * | 2000-05-13 | 2001-11-28 | 蛋白质技术国际公司 | Compositions and method for lowering low density lipoprotein cholesterol concn. |
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2002
- 2002-12-18 CN CNB02157491XA patent/CN1327788C/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07138277A (en) * | 1993-11-17 | 1995-05-30 | Pola Chem Ind Inc | Production of scymnol sulfate |
| CN1194843A (en) * | 1997-04-01 | 1998-10-07 | 李恩洪 | Method for producing green health medicine |
| JPH1146719A (en) * | 1997-08-04 | 1999-02-23 | Snow Brand Milk Prod Co Ltd | Nutrition composition |
| CN1273788A (en) * | 1999-05-15 | 2000-11-22 | 马锡洪 | Snack series |
| CN1302559A (en) * | 1999-11-26 | 2001-07-11 | Basf公司 | Curcumin preparation |
| CN1323544A (en) * | 2000-05-13 | 2001-11-28 | 蛋白质技术国际公司 | Compositions and method for lowering low density lipoprotein cholesterol concn. |
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| CN1429498A (en) | 2003-07-16 |
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