CN1325298A - 生产固态剂型的方法 - Google Patents
生产固态剂型的方法 Download PDFInfo
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- CN1325298A CN1325298A CN99812787A CN99812787A CN1325298A CN 1325298 A CN1325298 A CN 1325298A CN 99812787 A CN99812787 A CN 99812787A CN 99812787 A CN99812787 A CN 99812787A CN 1325298 A CN1325298 A CN 1325298A
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- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
- 229960002555 zidovudine Drugs 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Laminated Bodies (AREA)
Abstract
Description
维生素B复体 | 13.32% |
Klucel EF | 20.00% |
Isomalt | 66.68% |
参数 | T1 | T2 | T3 |
熔流速率(kg/h) | 25 | 25 | 25 |
螺杆转速(rpm) | 130 | 130 | 130 |
真空(毫巴) | 150 | 105 | 105 |
进料段温度(℃) | 23 | 23 | 23 |
段1温度(℃) | 80 | 80 | 80 |
段2温度(℃) | 100 | 100 | 100 |
段3温度(℃) | 110 | 110 | 110 |
段4温度(℃) | 110 | 110 | 110 |
机头温度(℃) | 120 | 120 | 120 |
口模温度(℃) | 120 | 120 | 125 |
压延机温度(℃) | 18 | 12 | 30 |
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19839276A DE19839276A1 (de) | 1998-08-28 | 1998-08-28 | Verfahren zur Herstellung von festen Dosierungsformen |
DE19839276.1 | 1998-08-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1325298A true CN1325298A (zh) | 2001-12-05 |
CN1170525C CN1170525C (zh) | 2004-10-13 |
Family
ID=7879077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB998127876A Expired - Lifetime CN1170525C (zh) | 1998-08-28 | 1999-08-27 | 生产固态剂型的方法 |
Country Status (9)
Country | Link |
---|---|
US (1) | US6669879B1 (zh) |
EP (1) | EP1107739B1 (zh) |
JP (1) | JP2002523185A (zh) |
CN (1) | CN1170525C (zh) |
AT (1) | ATE235896T1 (zh) |
CA (1) | CA2341646C (zh) |
DE (2) | DE19839276A1 (zh) |
ES (1) | ES2196853T3 (zh) |
WO (1) | WO2000012068A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102697660A (zh) * | 2012-06-04 | 2012-10-03 | 贵州景峰注射剂有限公司 | 一种去除微丸丸间静电的方法 |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
WO2001034119A2 (en) | 1999-11-12 | 2001-05-17 | Abbott Laboratories | Inhibitors of crystallization in a solid dispersion |
DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
GB0113841D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US7927616B2 (en) * | 2004-01-16 | 2011-04-19 | Thomas T. Yamashita | Pesticide compositions and methods for their use |
DK1748762T3 (en) * | 2004-05-28 | 2014-03-17 | Abbvie Deutschland | Dosage form which can be obtained from a powder mixture comprising an inorganic pigment |
WO2006045152A1 (en) * | 2004-10-29 | 2006-05-04 | Mayne Pharma International Pty Ltd | Improved tabletting process |
DE602004003399T2 (de) * | 2004-12-22 | 2007-10-04 | Mattern, Udo | Verwendung eines Behälters aus Plastik mit anorganischem Zusatzstoff |
US20060140820A1 (en) | 2004-12-28 | 2006-06-29 | Udo Mattern | Use of a container of an inorganic additive containing plastic material |
US8404275B2 (en) | 2007-07-01 | 2013-03-26 | Vitalis Llc | Combination tablet with chewable outer layer |
US20090269403A1 (en) * | 2008-04-24 | 2009-10-29 | Shaked Ze Ev | Oral contraceptive dosage forms and methods of making such dosage forms |
DE102011010437A1 (de) * | 2011-02-04 | 2012-08-09 | J. Rettenmaier & Söhne Gmbh + Co. Kg | Tablettierhilfsmittel |
US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
US20130040923A1 (en) | 2011-05-13 | 2013-02-14 | Trimel Pharmaceuticals Corporation | Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
WO2013063078A1 (en) | 2011-10-28 | 2013-05-02 | Vitalis Llc | Anti-flush compositions |
US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
US9375033B2 (en) | 2014-02-14 | 2016-06-28 | R.J. Reynolds Tobacco Company | Tobacco-containing gel composition |
US20170182070A1 (en) | 2014-10-08 | 2017-06-29 | Mayne Pharma International Pty Ltd. | Controlled Release Doxycycline |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3612211A1 (de) | 1986-04-11 | 1987-10-15 | Basf Ag | Kontinuierliches verfahren zum tablettieren |
WO1993007859A1 (en) * | 1991-10-23 | 1993-04-29 | Warner-Lambert Company | Novel pharmaceutical pellets and process for their production |
JPH06218028A (ja) * | 1992-10-02 | 1994-08-09 | Eisai Co Ltd | 湿製錠の成型方法とその装置及び湿製錠 |
DE4446467A1 (de) * | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von linsenförmigen Tabletten durch Schmelzkalandrierung |
DE4446468A1 (de) | 1994-12-23 | 1996-06-27 | Basf Ag | Verfahren zur Herstellung von umhüllten Tabletten |
DE19710213A1 (de) | 1997-03-12 | 1998-09-17 | Basf Ag | Verfahren zur Herstellung von festen Kombinationsarzneiformen |
-
1998
- 1998-08-28 DE DE19839276A patent/DE19839276A1/de not_active Withdrawn
-
1999
- 1999-08-27 US US09/763,662 patent/US6669879B1/en not_active Expired - Lifetime
- 1999-08-27 CN CNB998127876A patent/CN1170525C/zh not_active Expired - Lifetime
- 1999-08-27 WO PCT/EP1999/006314 patent/WO2000012068A1/de active IP Right Grant
- 1999-08-27 ES ES99946047T patent/ES2196853T3/es not_active Expired - Lifetime
- 1999-08-27 AT AT99946047T patent/ATE235896T1/de not_active IP Right Cessation
- 1999-08-27 CA CA002341646A patent/CA2341646C/en not_active Expired - Lifetime
- 1999-08-27 DE DE59904868T patent/DE59904868D1/de not_active Expired - Lifetime
- 1999-08-27 JP JP2000567188A patent/JP2002523185A/ja active Pending
- 1999-08-27 EP EP99946047A patent/EP1107739B1/de not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102697660A (zh) * | 2012-06-04 | 2012-10-03 | 贵州景峰注射剂有限公司 | 一种去除微丸丸间静电的方法 |
CN102697660B (zh) * | 2012-06-04 | 2014-02-12 | 贵州景峰注射剂有限公司 | 一种去除微丸丸间静电的方法 |
Also Published As
Publication number | Publication date |
---|---|
DE59904868D1 (de) | 2003-05-08 |
WO2000012068A1 (de) | 2000-03-09 |
EP1107739B1 (de) | 2003-04-02 |
EP1107739A1 (de) | 2001-06-20 |
US6669879B1 (en) | 2003-12-30 |
CA2341646C (en) | 2008-10-21 |
ATE235896T1 (de) | 2003-04-15 |
CA2341646A1 (en) | 2000-03-09 |
DE19839276A1 (de) | 2000-03-02 |
ES2196853T3 (es) | 2003-12-16 |
CN1170525C (zh) | 2004-10-13 |
JP2002523185A (ja) | 2002-07-30 |
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