CN1309406C - Medicinal preparation for treating rheumatism and rheumatoid diseases - Google Patents

Abstract

The present invention discloses a medicinal preparation for treating rheumatism and rheumatoid diseases. The medicinal preparation is prepared by using radix aconiti, wild aconite, rhizoma arisaematis, pinellia tuber, frankincense, myrrh, bombyx batryticatus, periostracum cicadae, schizonepeta, pangolin, red peony root, angelica and safflower as raw materials through a scientific processing technology. The medicinal preparation is used for treating rheumatism, rheumatoid arthritis, cervical spondylosis, shoulder periarthritis, lumbar intervertebral disc protrusion, sciatica, hyperosteogeny, etc. Because the medicine is prepared from pure Chinese herbal medicine, the medicinal preparation has little toxic and side effect, and treats both the manifestation causes and the root causes of a disease. The plaster preparation is convenient to apply, has conspicuous curative effect, and has no rebounding phenomenon after healing. Besides, clinical symptoms can rapidly disappear.

Description

A kind of pharmaceutical preparation for the treatment of rheumatic and rheumatoid diseases

Technical field:

The present invention relates to the medicine of rheumatism, rheumatoid disease, say it is to disclose a kind of pharmaceutical preparation for the treatment of rheumatic and rheumatoid diseases definitely, belong to the Chinese medicine technical field.

Background technology:

Rheumatism, the rheumatoid disease traditional Chinese medical science are commonly called as " arthromyodynia " and seriously perplex human beings'health.This disease is many to cause blood vessels obstructed because of wind and cold, damp, numbness resistance blood vessels, shows as muscle muscles and bones joint aches, numb, swelling, even red and swollen distortion, and weight person can cause the destruction of joint sclerotin, causes joint deformity, can't take care of oneself.In the Drug therapy process, the problem that runs into is: the state of an illness twines stupid, and Jing Jiu Bu More makes pathogen go deep into muscles and bones, and coagulation of QI-blood is not all right, and it is turbid to become the living phlegm-damp stasis of blood, and the meridians obturation is obstructed, and these product of non-vegetation can be led to, and must borrow worm Serpentis and so on search to pick and penetrate, and can open and coagulate.Medicine commonly used " controlling numbness looses ", " indometacin " etc., but easily recur after all existing drug withdrawal to some extent, grow and can lead to complications the course of treatment, and have than serious adverse.

Summary of the invention:

The present invention discloses a kind of pharmaceutical preparation for the treatment of rheumatic and rheumatoid diseases, have evident in efficacy, treating both the principal and secondary aspects of a disease characteristics, and cure the no rebound phenomena in back.

Technical solution of the present invention is as follows: according to pathogeny and the Therapeutic Principle of Chinese medicine to rheumatism, rheumatoid disease, with reference to the modern medicine achievement, in the medical treasure-house of motherland, choose and have wind-expelling and dispelling dampness, activating blood circulation to dissipate blood stasis, the pure Chinese herb medicine of anti-inflammatory analgetic is made Chinese medicine preparation through science.

The present invention is made of by weight following medicine:

Radix Aconiti 50-80, Radix Aconiti Kusnezoffii 50-80, Rhizoma Arisaematis 40-55, Rhizoma Pinelliae 40-55, Olibanum 50-60, Myrrha 50-60, Bombyx Batryticatus 30-40, Periostracum Cicadae 30-40, Herba Schizonepetae 25-30, Squama Manis 25-30, Radix Paeoniae Rubra 20-30, Radix Angelicae Sinensis 20-30, Flos Carthami 30-40;

Adopt traditional plaster production technology to make the plaster preparation;

Above-mentioned prescription of the present invention also can be made into other dosage forms pharmaceutically.

Whenever force on and contain crude drug: 30～55 grams.

Using method: directly stick on disease sites.

Be hot product with Radix Aconiti, Radix Aconiti Kusnezoffii among the present invention,, have expelling wind and removing dampness, temperature three-way meridian effect and analgesic effect as monarch drug; Rhizoma Arisaematis, Rhizoma Pinelliae drying dampness to eliminate phlegm to remove the phlegm-damp in the meridians, also have the pain relieving effect, with being ministerial drug; Assistant Olibanum, Myrrha promoting flow of QI and blood to change the blood stasis in the network, make the QI and blood smoothness; Pleasant impression medicines such as Bombyx Batryticatus, Periostracum Cicadae, Herba Schizonepetae, Squama Manis, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Flos Carthami close and use it, and then turbid, the blood stasis of wind-cold damp pathogen and expectorant all can be dispeled, and makes meridians be led to it, and all diseases can be healed.

Characteristics of the present invention are: pure Chinese herbal medicine is made, toxic and side effects is little, treating both the principal and secondary aspects of a disease, evident in efficacy, clinical symptom disappearance is rapid, cure the no rebound phenomena in back, be adapted to the treatment of various rheumatic and rheumatoid arthritis aches, cervical spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, sciatica, hyperosteogeny diseases.

For showing the therapeutic effect of medicine of the present invention, through system's clinical observation: selected case history is divided into 2 groups at random, treatment group (A group) 147 examples, and male's 63 examples, the women 84; Age 19-68 year, average 51 years old; Rheumatic arthritis 49 examples wherein, rheumatoid arthritis 62 examples, other (as cervical spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, sciatica, hyperosteogeny etc.) 36 examples.Matched group 128 examples are male's 59 examples wherein, and the women 69; Age 18-65 year, 48 years old mean age, rheumatic arthritis 36 examples wherein, rheumatoid arthritis 62 examples, other (as cervical spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, sciatica, hyperosteogeny etc.) 30 examples.2 groups of cases are checked through t at aspects such as age, sex, the courses of disease, and difference does not have the significance meaning.Wherein smelting treatment group selects for use ointment of the present invention to stick, and matched group is selected " the deep ball of Jin wind " of vegetable garden board for use.

Criterion of therapeutical effect: (diagnostic criteria) carried out with reference to " the clinical research guideline of new Chinese medicine treatment numbness disease ".

Clinical cure: symptom all disappears, and it is normal that functional activity recovers; Main doctor trained in Western medicine physico-chemical examination is normal.

Produce effects: symptomatology disappears or main disease is eliminated, and function of joint is recovered substantially, can participate in normal work or physical labor; The physico-chemical examination index is normal substantially.

Effectively: cardinal symptom disappears substantially, and main function of joint is recovered substantially or had made marked progress, and can't take care of oneself transfers to and can take care of oneself, or loses the job and work and can state recover to some extent; Main physical and chemical index makes moderate progress.

Invalid: with the treatment before compare, each side does not all have progress.

Therapeutic outcome:

147 examples are organized in clinical total effects treatment, clinical cure 68 examples (46.3%), produce effects 42 examples (%28.6), effective 21 examples (14.3), invalid 16 examples (10.8), total effective rate 89.2%.Matched group 128 examples, clinical cure 31 examples (24.2%), produce effects 26 examples (20.3%), effective 19 examples (14.8%), invalid 52 examples (40.7%), total effective rate 59.3%.Two groups relatively, and the treatment group significantly is better than matched group.See the following form:

Group	Clinical cure	Produce effects	Effectively	Invalid	Total effective rate (%)
						Treatment group 147	68(46.3)	42(28.6)	21(14.3)	16(10.8)	89.2
Matched group 128	31(24.2)	26(20.3)	19(14.8)	52(40.7)	59.3

Case 1

Zhang, sex: man, age: 55 years old;

The main suit: breath rheumatoid 30 years, moist ill because of being subjected in one's early years, weight when light during the state of an illness was once sought medical advice in inside and outside the province how tame hospital, and poor effect, the state of an illness but increase the weight of so far day by day, can't take care of oneself.

Symptom: duplex can not stretch two wrist moderates tetanic (the light activity degree is arranged), both shoulders pain, both arms can not go up act, two hip, two swelling and pain in knee, can not squat down, two ankle swells and ache, can only move and walk.

Chemical examination: RF (+) ESR:85mm/h resists " 0 ":＜500u

Diagnosis: rheumatoid arthritis, functional classification IV;

Adopt medical ointment plaster applying treatment of the present invention, through three courses of treatment, two wrists, duplex, both shoulders activity freely, two knee joints can be squatted down, the disappearance of swelling and ache is advised it to continue to stick ointment of the present invention and is consolidated two courses of treatment, follows up a case by regular visits to so far recurrence.

Case 2:

Record certain, sex: woman, age: 42 years old;

The main suit: because of puerperal careless, suffered from rheumatoid 12 years, the state of an illness is very serious, shows effect repeatedly by the multi-treatment state of an illness, causes and can't work.

Symptom: left finesse feels pain, gradually swelling, the distortion of left hand middle finger is at local hospital admission, the chemical examination rheumatoid factor positive, erythrocyte sedimentation rate 90mm/n, anti-" 0 ":＜480u begins with the treatment of Western medicine diclofenac, the state of an illness alleviates often bounce-back of back, after use Chinese herbal medicine decoction treatment instead, but poor effect, low thermal phenomenon is persistent.

Use this patent medical ointment plaster applying treatment after course of treatment the left finesse pain disappear, swelling is progressively gone down, it is normal that the distortion of left hand middle finger slowly recovers, and follows the doctor's advice to return to one's perfect health after continuing to use ointment to stick two courses of treatment, and return to duty, follows up a case by regular visits to so far recurrence.

The specific embodiment:

Embodiment 1

Take by weighing raw material by following proportioning: Radix Aconiti 50g, Radix Aconiti Kusnezoffii 58g, Rhizoma Arisaematis 55g, Rhizoma Pinelliae 45g, Olibanum 50g, Myrrha 50g, Bombyx Batryticatus 30g, Periostracum Cicadae 30g, Herba Schizonepetae 25g, Squama Manis 30g, Radix Paeoniae Rubra 20g, Radix Angelicae Sinensis 25g, Flos Carthami 30g, the said medicine pulverize separately is become 80～110 order fine powders, behind the mix homogeneously, putting into 2.5 times of volume Adeps Sus domesticas or Oleum sesami soaked 3-8 days, mild and heavy respiration decocts, the oil temperature control is at 200-320 ℃, and is fried shrivelled to medicine, pulls medicinal residues out, medicine oil is standby.

Medicine oil is heated to more than 320 ℃, when dripping the beading attitude, Colophonium, the white beeswax adding of fusing, stop heating, be sprinkled into the Plumbum preparatium fine powder while hot, constantly stir, make it be fused into paste, pour in the cold water with the thread shape immediately, stir and make its one-tenth ribbon shape, continue to stir, after to be cooled the condensing, pull out and remove moisture, to remove the composition of ointment moderate stimulation skin, be heated to fusing again, take out to share and make the plaster preparation on ground paper and cloth, 35～55g medicine is subsides.

Embodiment 2

Take by weighing raw material by following proportioning: Radix Aconiti 70g, Radix Aconiti Kusnezoffii 80g, Rhizoma Arisaematis 50g, Rhizoma Pinelliae 55g, Olibanum 50g, Myrrha 50g, Bombyx Batryticatus 35g, Periostracum Cicadae 30g, Herba Schizonepetae 30g, Squama Manis 30g, Radix Paeoniae Rubra 25g, Radix Angelicae Sinensis 25g, Flos Carthami 35g, the said medicine pulverize separately is become 100 order fine powders, behind the mix homogeneously, Adeps Sus domestica or the Oleum sesami of putting into 5.0 times of volumes soaked 8 days, mild and heavy respiration decocts, the oil temperature control is at 200-320 ℃, and is fried shrivelled to medicine, pulls medicinal residues out, medicine oil is standby.

Medicine oil is heated to more than 320 ℃, when dripping the beading attitude, Colophonium, the white beeswax adding of fusing, stop heating, be sprinkled into the Plumbum preparatium fine powder while hot, constantly stir, make it be fused into paste, pour in the cold water with the thread shape immediately, stir and make its one-tenth ribbon shape, continue to stir, after to be cooled the condensing, pull out and remove moisture, to remove the composition of ointment moderate stimulation skin, be heated to fusing again, take out to share and make the plaster preparation on ground paper and cloth, 35～55g medicine is subsides.

Claims (2)

1, a kind of drug agents for the treatment of rheumatic and rheumatoid diseases, wherein make raw materials of effective components medicine and weight proportion thereof and be:

Radix Aconiti 50-80, Radix Aconiti Kusnezoffii 50-80, Rhizoma Arisaematis 40-55, Rhizoma Pinelliae 40-55, Olibanum 50-60,

Myrrha 50-60, Bombyx Batryticatus 30-40, Periostracum Cicadae 30-40, Herba Schizonepetae 25-30, Squama Manis 25-30,

Radix Paeoniae Rubra 20-30, Radix Angelicae Sinensis 20-30, Flos Carthami 30-40.

2,, it is characterized in that it is the plaster dosage form according to the drug agents of the described treatment rheumatic and rheumatoid diseases of claim 1.