CN1298350C - Medicinal spirit for rheumatic arthritis - Google Patents

Medicinal spirit for rheumatic arthritis Download PDF

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Publication number
CN1298350C
CN1298350C CNB2004100241663A CN200410024166A CN1298350C CN 1298350 C CN1298350 C CN 1298350C CN B2004100241663 A CNB2004100241663 A CN B2004100241663A CN 200410024166 A CN200410024166 A CN 200410024166A CN 1298350 C CN1298350 C CN 1298350C
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radix
root
parched
rheumatic arthritis
sorghum
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CN1583058A (en
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刘正东
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Abstract

The present invention discloses medicated spirits for treating rheumatic arthritis, which are proportionally prepared from the raw materials of pawpaw, radix saposhinokoviae from northeast, notopterygium root, himalayan teasel root, clematis root, scorpion, bombyx batryticatus, atractylodes rhizome, achyranthes root, motherwort, cortex illicii, perilla stem, cassia twig, psoralea, sappan wood, licorice root, grain sorghum stem root and pure sorghum spirits. The present invention has the functions of expelling wind and coldness, warming and dredging channels and collaterals, removing dampness and swelling, promoting blood circulation and alleviating pain, has favorable effects on treating or relieving symptoms of rheumatic arthritis, etc., and has no obvious toxic or side effect. The medicated spirits can be accepted by patients easily and can be suitable for long-term use.

Description

A kind of medicated wine for the treatment of rheumatic arthritis
The present invention relates to a kind of medicated wine, a kind of specifically is the medicated wine of the treatment rheumatic arthritis of feedstock production with Chinese medicine.
China has various rheumatic arthritis (motherland's medical science is referred to as arthromyodynia) patient now and accounts for 3% of total population, and promptly 4,000 ten thousand.The treatment means of doctor trained in Western medicine mostly is and adopts non-steroidal anti-inflammatory drug (as aspirin, ibuprofen, indometacin etc.) at present, but owing to there is significantly untoward reaction, is difficult to adhere to take medicine for a long time; Though the treatment by Chinese herbs untoward reaction is less, the inconvenience of its medicining mode then brings very big mental burden to the patient; Its late result of physical therapy and acupuncture and moxibustion therapy still can not get certainly.
Purpose of the present invention aims to provide and a kind ofly can either play fine treatment or relief of symptoms effect, the form of Chinese drug that the patient is taken like a shot again to rheumatic arthritis.It both can be used as medicine, and dosage according to the rules is step-by-step to be taken, and can be used as pick-me-up again and arbitrarily drink it.
Solution of the present invention is according to understanding and the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs principle of the traditional Chinese medical science to rheumatic arthritis (arthromyodynia), according to traditional Chinese medical science prescription and the medicated wine that processes of preparation principle.
Chinese herbal medicine of the present invention is formed (consumption is a weight portion, and the back is together) by following component:
Fructus Chaenomelis 9~18, RADIX SAPOSHINOKOVIAE from Northeast 9~18, Rhizoma Et Radix Notopterygii 9~18, Radix Dipsaci 9~18, Radix Clematidis 9~18, Scorpio 9~18, Bombyx Batryticatus (vinegar stir-fry) 9~18, Rhizoma Atractylodis (parched with bran) 9~18, Radix Achyranthis Bidentatae 9~18, Herba Leonuri 9~18, Cortex schizophragmatis integrifolii radicis 9~18, Caulis Perillae 9~18, Ramulus Cinnamomi 9~18, Fructus Psoraleae 9~18, Lignum Sappan 9~18, Radix Glycyrrhizae 13~27,6~11 of Sorghum vulgare Pers. prop roots (getting the part that is exposed on the soil) (per 1000 gram Chinese liquor, the back is together), the pure sorghum wine 1000~2000 of 40~65 degree.
Optimum ratio of the present invention is:
Fructus Chaenomelis 13~16, RADIX SAPOSHINOKOVIAE from Northeast 13~16, Rhizoma Et Radix Notopterygii 13~16, Radix Dipsaci 13~16, Radix Clematidis 13~16, Scorpio 13~16, Bombyx Batryticatus (vinegar stir-fry) 13~16, Rhizoma Atractylodis (parched with bran) 13~16, Radix Achyranthis Bidentatae 13~16, Herba Leonuri 13~16, Cortex schizophragmatis integrifolii radicis 13~16, Caulis Perillae 13~16, Ramulus Cinnamomi 13~16, Fructus Psoraleae 13~16, Lignum Sappan 13~16, Radix Glycyrrhizae 22~25,7~9 of Sorghum vulgare Pers. prop roots (getting the part that is exposed on the soil), the pure sorghum wine 1200~1600 of 50~60 degree.
Optimal proportion of the present invention is:
Fructus Chaenomelis 15, RADIX SAPOSHINOKOVIAE from Northeast 15, Rhizoma Et Radix Notopterygii 15, Radix Dipsaci 15, Radix Clematidis 15, Scorpio 15, Bombyx Batryticatus (vinegar stir-fry) 15, Rhizoma Atractylodis (parched with bran) 15, Radix Achyranthis Bidentatae 15, Herba Leonuri 15, Cortex schizophragmatis integrifolii radicis 15, Caulis Perillae 15, Ramulus Cinnamomi 15, Fructus Psoraleae 15, Lignum Sappan 15, Radix Glycyrrhizae 24,7 of Sorghum vulgare Pers. prop roots (getting the part that is exposed on the soil), the pure sorghum wine 1250 of 60 degree.
Above-mentioned each component is placed container, and the sealing of impouring Chinese liquor is imbedded underground solar radiation place and is taken after 30 days, takes 25~30 milliliters every day 2 times at every turn, and 1000 milliliters is a course of treatment.
Each component among the present invention can play promoting blood circulation, row medicine gesture, help the effect of the efficacy of a drug in Chinese liquor, thereby can expelling wind and cold, temperature three-way meridian, dehumidifying detumescence, promoting blood circulation and stopping pain, nourishing the liver and kidney, strong muscles and bones, the effect of treatment preferably or relief of symptoms is arranged for rheumatic arthritis, rheumatoid arthritis and scapulohumeral periarthritis etc., and the present invention does not have obvious toxic-side effects, the patient is easy to accept, and is suitable for taking for a long time.
Most preferred embodiment of the present invention is as follows:
Rheumatic arthritis is a kind of commonly encountered diseases, is that its cardinal symptom is a pain owing to due to the osteoarticular degeneration, be main pathological change with cervical vertebra, lumbar vertebra, knee joint hyperosteogeny often.The treatment means of doctor trained in Western medicine mostly is and adopts nonsteroidal anti-inflammatory analgetic thing (as aspirin, ibuprofen, indometacin etc.) at present, but owing to there is significantly untoward reaction, usually brings very big psychological burden to the patient; Its late result still seldom arrives certainly though physical therapy and acupuncture and moxibustion therapy untoward reaction are less; Though oral Chinese medicine can overcome above-mentioned shortcoming, the patient is often because of disliking " trouble " to be reluctant to accept; Also have on the market common as " Unguentum Moschus et Os Tigris " though easy to use since some raw material (as Os Tigris) thus scarcity its curative effect is had a greatly reduced quality.For this reason, we are absorbing the experience in ancient times, on the basis of reference for modern achievement in research, according to understanding and the determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs rule of the traditional Chinese medical science to osteoarthritis, according to traditional Chinese medical science prescription and preparation principle, what process has developed a kind of medicated wine (medical wind for treating rheumatism) for the treatment of rheumatic arthritis, from year November in May, 1997 to 1,999 70 routine rheumatic arthritis patients has been carried out the clinical observation of system.Now the result is reported as follows:
1. physical data
The observation case all derives from the Feicheng and crosses the commune hospital, villages and small towns, amounts to 70 examples, is divided into two groups at random, and 38 examples are organized in treatment, man's 22 examples, women 18 examples, minimum 46 years old of age, maximum 69 years old, the elder of the course of disease 17 years, the shortest person half a year, average 6.4 years, matched group 32 examples, male 19 examples, woman's 13 examples, minimum 47 years old of age, maximum 68 years old, the elder of the course of disease 16 years, the shortest person 7 months, average 6.2 years.
2. diagnostic criteria
According to the diagnostic criteria that Ceng Qingyu chief editor " osteoarthritis " (Tianjin science tech publishing house) works out, comprise pain, morning is stiff and gluing sense and limbs radiating pain.And eliminating tumor, metabolic disease and part-structure disease.
3. Therapeutic Method
The treatment group is given this medicated wine, takes 25~30 milliliters at every turn, and every day 2 times, 1000 milliliters is a course of treatment.Interval 2~3 days, 4 courses of treatment of logotype, the other drug of stopping using therebetween.
The component of this medicated wine is: Fructus Chaenomelis 15, RADIX SAPOSHINOKOVIAE from Northeast 15, Rhizoma Et Radix Notopterygii 15, Radix Dipsaci 15, Radix Clematidis 15, Scorpio 15, Bombyx Batryticatus (vinegar stir-fry) 15, Rhizoma Atractylodis (parched with bran) 15, Radix Achyranthis Bidentatae 15, Herba Leonuri 15, Cortex schizophragmatis integrifolii radicis 15, Caulis Perillae 15, Ramulus Cinnamomi 15, Fructus Psoraleae 15, Lignum Sappan 15, Radix Glycyrrhizae 24,7 of Sorghum vulgare Pers. prop roots (getting the part that is exposed on the soil).Above-mentioned each component is placed container, and sealing in pure sorghum wine 1250 grams of impouring 60 degree is imbedded underground solar radiation place and is taken after 30 days,
Matched group gives homemade ibuprofen 0.4g oral, every day three times, logotype 2 months.
Two groups of cases all the 1st week, the 2nd 1st month week and 2nd month are observed cardinal symptom and sign after medication.
4. curative effect determinate standard
The percentage scoring method that adopts Huskisson to propose, i.e. visual simulation pain scale (Visualanalogue pain scale VAPS) is promptly used 100 millimeters straight lines, and an end is painless, and the other end is for the most bitterly.Patient regularly marks the degree of its pain on line in the same time of this day.In conjunction with clinical practice, be defined as clinical basic healing, produce effects, effective and invalid 4 grades, and some cases is followed up a case by regular visits to.
The concrete standard of 4 grades of curative effects is as follows:
Clinical basic healing: 1. pain symptom disappears; 2.VAPS<20.
Produce effects: 1. pain symptom obviously alleviates; 2.VAPS 20~50.
Effectively: 1. pain symptom alleviates; 2.VAPS 21~80.
Invalid: 1. pain symptom alleviates not obvious; 2.VAPS more than 80.
5. therapeutic outcome
Therapeutic outcome sees the following form:
Table 1 liang group curative effect relatively
Clinical basic healing Produce effects Effectively Invalid Total effective rate (%)
Treatment group matched group 11 6 13 8 9 7 5 11 86.84 65.62
The P value <0.01 <0.01* <0.01
* produce effects comprises that clinical basic healing and produce effects sum compare.
As can be seen from Table 1, clinical basic healing, obvious effective rate and effective percentage more all have significant difference for two groups, and (P<0.01) has illustrated that treatment group curative effect is better than matched group.
The routine urianlysis result: in order to detect the influence of this medicated wine to kidney, to all doing routine urianlysis before and after all patient, the result there is no unusually, illustrates that this medicated wine has no side effect to kidney.
Untoward reaction, this medicated wine with after slight gastric burn feeling can be arranged, be due to the alcohol function.Need not handle, spend 1~3 hour and can eliminate voluntarily.
Follow up a case by regular visits to: by following up a case by regular visits to the half a year of treatment being organized effective 33 people, find stable disease person's 28 examples, accounting for 84.85%, 5 example has repeatedly, alleviates after medication second course of treatment, illustrates that the late result of this medicated wine is also better.
Model case
(summary)
Discuss
Each component in this medicated wine can play promoting blood circulation, row medicine gesture, help the effect of the efficacy of a drug in Chinese liquor, thereby can expelling wind and cold, temperature three-way meridian, dehumidifying detumescence, promoting blood circulation and stopping pain, nourishing the liver and kidney, strong muscles and bones, thereby the effect of treatment or relief of symptoms arranged preferably for the pain that rheumatic arthritis, rheumatoid arthritis and scapulohumeral periarthritis etc. cause, and the present invention does not have obvious toxic-side effects, using method is easy, the patient is easy to accept, and is suitable for taking for a long time.

Claims (3)

1. a medicated wine for the treatment of rheumatic arthritis according to composition by weight, places the Chinese liquor sealing to form in 30 days by Chinese herbal medicine, it is characterized in that Chinese herbal medicine is made up of following component:
Fructus Chaenomelis 9~18, RADIX SAPOSHINOKOVIAE from Northeast 9~18, Rhizoma Et Radix Notopterygii 9~18, Radix Dipsaci 9~18, Radix Clematidis 9~18, Scorpio 9~18, vinegar Bombyx Batryticatus (parched) 9~18, parched with bran Rhizoma Atractylodis 9~18, Radix Achyranthis Bidentatae 9~18, Herba Leonuri 9~18, Cortex schizophragmatis integrifolii radicis 9~18, Caulis Perillae 9~18, Ramulus Cinnamomi 9~18, Fructus Psoraleae 9~18, Lignum Sappan 9~18, Radix Glycyrrhizae 13~27,6~11 of Sorghum vulgare Pers. prop roots, the pure sorghum wine 1000~2000 of 40~65 degree.
2. medicated wine as claimed in claim 1 is characterized in that, Chinese herbal medicine can be taked following component according to weight portion:
Fructus Chaenomelis 13~16, RADIX SAPOSHINOKOVIAE from Northeast 13~16, Rhizoma Et Radix Notopterygii 13~16, Radix Dipsaci 13~16, Radix Clematidis 13~16, Scorpio 13~16, vinegar Bombyx Batryticatus (parched) 13~16, parched with bran Rhizoma Atractylodis 13~16, Radix Achyranthis Bidentatae 13~16, Herba Leonuri 13~16, Cortex schizophragmatis integrifolii radicis 13~16, Caulis Perillae 13~16, Ramulus Cinnamomi 13~16, Fructus Psoraleae 13~16, Lignum Sappan 13~16, Radix Glycyrrhizae 22~25,7~9 of Sorghum vulgare Pers. prop roots, the pure sorghum wine 1200~1600 of 50~60 degree.
3. medicated wine as claimed in claim 1 is characterized in that, Chinese herbal medicine can be taked following component according to weight portion:
Fructus Chaenomelis 15, RADIX SAPOSHINOKOVIAE from Northeast 15, Rhizoma Et Radix Notopterygii 15, Radix Dipsaci 15, Radix Clematidis 15, Scorpio 15, vinegar Bombyx Batryticatus (parched) 15, parched with bran Rhizoma Atractylodis 15, Radix Achyranthis Bidentatae 15, Herba Leonuri 15, Cortex schizophragmatis integrifolii radicis 15, Caulis Perillae 15, Ramulus Cinnamomi 15, Fructus Psoraleae 15, Lignum Sappan 15, Radix Glycyrrhizae 24,7 of Sorghum vulgare Pers. prop roots, the pure sorghum wine 1250 of 60 degree.
CNB2004100241663A 2004-05-29 2004-05-29 Medicinal spirit for rheumatic arthritis Expired - Fee Related CN1298350C (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163130A (en) * 1996-04-25 1997-10-29 蔡昌顺 Tonic wine containing black-tail snake, root of American ginseng and astragalus root and its preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1163130A (en) * 1996-04-25 1997-10-29 蔡昌顺 Tonic wine containing black-tail snake, root of American ginseng and astragalus root and its preparation

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Granted publication date: 20070207