CN1247605C - 新型半乳糖苷神经酰胺类似体、使用这些类似体的β-葡糖脑苷酯酶活化剂、皮肤外用药以及β-葡糖脑苷酯酶的活化方法 - Google Patents
新型半乳糖苷神经酰胺类似体、使用这些类似体的β-葡糖脑苷酯酶活化剂、皮肤外用药以及β-葡糖脑苷酯酶的活化方法 Download PDFInfo
- Publication number
- CN1247605C CN1247605C CNB028131487A CN02813148A CN1247605C CN 1247605 C CN1247605 C CN 1247605C CN B028131487 A CNB028131487 A CN B028131487A CN 02813148 A CN02813148 A CN 02813148A CN 1247605 C CN1247605 C CN 1247605C
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- China
- Prior art keywords
- general formula
- beta
- glucocerebrosidase
- utilize
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
Abstract
Description
Claims (10)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001196016A JP4070966B2 (ja) | 2001-06-28 | 2001-06-28 | 新規ガラクトシルセラミド類縁体及び用途 |
JP196016/2001 | 2001-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1522263A CN1522263A (zh) | 2004-08-18 |
CN1247605C true CN1247605C (zh) | 2006-03-29 |
Family
ID=19033898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028131487A Expired - Lifetime CN1247605C (zh) | 2001-06-28 | 2002-06-27 | 新型半乳糖苷神经酰胺类似体、使用这些类似体的β-葡糖脑苷酯酶活化剂、皮肤外用药以及β-葡糖脑苷酯酶的活化方法 |
Country Status (9)
Country | Link |
---|---|
US (2) | US7183261B2 (zh) |
EP (1) | EP1408045B1 (zh) |
JP (1) | JP4070966B2 (zh) |
KR (1) | KR100739250B1 (zh) |
CN (1) | CN1247605C (zh) |
DE (1) | DE60232449D1 (zh) |
HK (1) | HK1067642A1 (zh) |
TW (2) | TW201002734A (zh) |
WO (1) | WO2003002584A1 (zh) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101936685B1 (ko) * | 2011-11-16 | 2019-01-11 | (주)아모레퍼시픽 | 글리코실 세라마이드 유사 화합물, 이의 제조방법 및 이를 함유하는 화장료 조성물 |
JP5918168B2 (ja) * | 2012-04-27 | 2016-05-18 | 富士フイルム株式会社 | β−グルコセレブロシダーゼ活性増強剤 |
WO2014053482A1 (en) | 2012-10-03 | 2014-04-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza with invariant nkt cell agonists |
KR101589633B1 (ko) * | 2014-09-18 | 2016-02-01 | 한국과학기술연구원 | 당세라마이드 유도체 및 이의 제조방법 |
US20180185368A1 (en) | 2014-11-06 | 2018-07-05 | Lysosomal Therapeutics Inc. | Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders |
EP3215510B1 (en) | 2014-11-06 | 2023-06-07 | Bial-R&D Investments, S.A. | Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders |
EP3215511B1 (en) | 2014-11-06 | 2024-04-17 | Bial-R&D Investments, S.A. | Substituted pyrazolo(1,5-a)pyrimidines and their use in the treatment of medical disorders |
US10858410B2 (en) | 2015-08-12 | 2020-12-08 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Glycosylated peptides with pseudoproline residues and having enhanced half-lives and ability to cross the blood brain barrier |
EP3344276B1 (en) | 2015-09-03 | 2020-04-22 | The Board of Regents of the University of Oklahoma | Peptide inhibitors of clostridium difficile tcdb toxin |
MX2018012207A (es) | 2016-04-06 | 2019-03-28 | Lysosomal Therapeutics Inc | Compuestos de pirrol[1,2-a]pirimidinil carboxamida y su uso en el tratamiento de trastornos médicos. |
CA3020287A1 (en) | 2016-04-06 | 2017-10-12 | Lysosomal Therapeutics Inc. | Pyrazolo[1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
WO2017176961A1 (en) | 2016-04-06 | 2017-10-12 | Lysosomal Therapeutics Inc. | Imidazo [1,5-a]pyrimidinyl carboxamide compounds and their use in the treatment of medical disorders |
US11345698B2 (en) | 2016-05-05 | 2022-05-31 | Bial—R&D Investments, S.A. | Substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-a]pyrazines, related compounds, and their use in the treatment of medical disorders |
AU2017261291C1 (en) | 2016-05-05 | 2022-05-26 | Bial - R&D Investments, S.A. | Substituted imidazo[1,2-b]pyridazines, substituted imidazo[1,5-b]pyridazines, related compounds, and their use in the treatment of medical disorders |
WO2017207040A1 (en) | 2016-06-01 | 2017-12-07 | Vib Vzw | ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR |
US10933126B2 (en) | 2018-05-03 | 2021-03-02 | The Board Of Regents Of The University Of Oklahoma | Clostridium difficile immunogenic compositions and methods of use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07110872B2 (ja) * | 1990-09-25 | 1995-11-29 | 株式会社ディ・ディ・エス研究所 | 酸性糖脂質及び微粒子キャリヤー |
JP2774417B2 (ja) * | 1991-08-07 | 1998-07-09 | 株式会社ディ・ディ・エス研究所 | ペプチド骨格を有する分枝鎖型糖複合体及び微粒子キャリヤー |
IT1271624B (it) | 1994-03-21 | 1997-06-04 | Lifegroup Spa | Derivati glucosidici di n-acil alchilamine capaci di esercitare effetto o neuroprotettivo utilizzabili nelle patologie acute e croniche del sistema nervoso centrale correlate ad eccitotossicita' |
JP2896321B2 (ja) | 1994-10-27 | 1999-05-31 | 鐘紡株式会社 | β−グルコセレブロシダーゼの活性化方法 |
-
2001
- 2001-06-28 JP JP2001196016A patent/JP4070966B2/ja not_active Expired - Lifetime
-
2002
- 2002-06-27 US US10/482,110 patent/US7183261B2/en not_active Expired - Lifetime
- 2002-06-27 DE DE60232449T patent/DE60232449D1/de not_active Expired - Lifetime
- 2002-06-27 WO PCT/JP2002/006532 patent/WO2003002584A1/ja active Application Filing
- 2002-06-27 EP EP02743752A patent/EP1408045B1/en not_active Expired - Lifetime
- 2002-06-27 KR KR1020037016943A patent/KR100739250B1/ko active IP Right Grant
- 2002-06-27 TW TW098132688A patent/TW201002734A/zh unknown
- 2002-06-27 TW TW091114141A patent/TWI322151B/zh not_active IP Right Cessation
- 2002-06-27 CN CNB028131487A patent/CN1247605C/zh not_active Expired - Lifetime
-
2005
- 2005-01-28 HK HK05100756A patent/HK1067642A1/xx not_active IP Right Cessation
-
2007
- 2007-01-11 US US11/651,978 patent/US20070111951A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60232449D1 (de) | 2009-07-09 |
TWI322151B (zh) | 2010-03-21 |
US7183261B2 (en) | 2007-02-27 |
KR100739250B1 (ko) | 2007-07-12 |
EP1408045B1 (en) | 2009-05-27 |
US20040242499A1 (en) | 2004-12-02 |
EP1408045A1 (en) | 2004-04-14 |
US20070111951A1 (en) | 2007-05-17 |
KR20040048381A (ko) | 2004-06-09 |
TW201002734A (en) | 2010-01-16 |
CN1522263A (zh) | 2004-08-18 |
JP2003012684A (ja) | 2003-01-15 |
EP1408045A4 (en) | 2005-12-28 |
WO2003002584A1 (fr) | 2003-01-09 |
HK1067642A1 (en) | 2005-04-15 |
JP4070966B2 (ja) | 2008-04-02 |
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C06 | Publication | ||
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Owner name: KANEBO COSMETICS INC. Free format text: FORMER OWNER: KANEBO LTD. Effective date: 20041105 |
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C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20041105 Address after: Tokyo, Japan Applicant after: Bell Textile Co.,Ltd. Address before: Tokyo, Japan Applicant before: KANEBO, LTD. |
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Effective date of registration: 20060721 Address after: Tokyo, Japan Patentee after: KAO Corp. Address before: Tokyo, Japan Patentee before: Bell Textile Co.,Ltd. |
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