CN1244712C - Coating process for TiNi inner support rack - Google Patents
Coating process for TiNi inner support rack Download PDFInfo
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- CN1244712C CN1244712C CN 00112312 CN00112312A CN1244712C CN 1244712 C CN1244712 C CN 1244712C CN 00112312 CN00112312 CN 00112312 CN 00112312 A CN00112312 A CN 00112312A CN 1244712 C CN1244712 C CN 1244712C
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- inner support
- support frame
- tini
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Abstract
The present invention relates to a film coating process for TiNi inner support frames, which comprises two main steps, wherein in step one, the surface of a TiNi support frame is treated by plasma modification, and the plasma modification treatment can be a direct current plasma mode, a radio frequency plasma mode or a microwave plasma mode; in step two, the surface of the TiNi support frame is firmly coated with a C-shaped poly-p-xylene film with the thickness of 1 to 2 micrometers by the existing chemical vapour deposition process. The process of the present invention not only keeps the original memory characteristic, deformability, hyperelasticity and adaptability, but also improves stability and reliability related to the biological aspect.
Description
Technical field
The present invention relates to the metallic surface coating process, especially the Ti-Ni alloy inner support frame is coated with technology with polymeric membrane for a kind of.
Background technology
TiNi alloy inner support frame is a kind of combined type shape memory alloy inner support frame that is widely used in the narrow property of hospital clinical treatment human internal organ disease.At present the inner support frame made of the super elastic characteristics of utilization TiNi shape memory alloy is compared with embolism materials that can not deformation commonly used, have easy to operate, applied widely, advantages such as result of treatment is good, biomedicine evaluation for the TiNi alloy, till now, from the experimental result reported as can be known, the TiNi alloy is with medically the most widely used stainless steel, CoCr alloy almost have equal biocompatibility at present.It still is behind the TiNi alloy implantable bioartificial body that but the clinical application of TiNi alloy gives the mystery of people's maximum, the Ni element stripping problem of its alloy.Although can think that the biocompatibility experiment of TiNi alloy in the quite a while should be reliable and effective, and the stripping quantity that closes unanimous middle Ni element also is extremely micro-, but real evaluation, also need the experiment interior through secular organism, that organism is outer behind the particularly long-term implant into body, thereby finally estimate out the biological stability and the reliability of this metal alloy compositions.
Summary of the invention
Purpose of the present invention is exactly to have had special domestic animal of shape memory and a hyperelastic TiNi alloy inner support frame at what be used widely, a kind of coating process is provided, so that multiple last layer blood compatibility and the reliable and stable C type parylene film (polymeric membrane) of histocompatibility are draped over one's shoulders in TiNi silk surface, it is united two into one, become a kind of novel higher combined type shape memory alloy inner support frame of biological stability reliability, so just can allow people carry out clinical treatment fully relievedly and bring benefit to the mankind.
For achieving the above object, of the present invention having provided a kind ofly is coated with polymeric membrane technology to the TiNi inner support frame,
This technology may further comprise the steps,
The first, adopt radio-frequency plasma mode or direct-current plasma mode or microwave plasma mode that plasma modification is carried out on Ti-Ni alloy inner support frame surface and handle;
The second, adopt chemical vapor deposition method make Ti-Ni alloy inner support frame surface firm drape over one's shoulders multiple last layer C type parylene film; It is characterized in that:
The thickness of C type parylene film is 1 to 2 micron; Adopt in the processing condition that the radio-frequency plasma mode handles Ti-Ni alloy inner support frame surface: radio frequency power is that 80-100W, ar pressure are that 80 to 300 mmhg, rf frequency are 8 to 12MHZ, the plasma modification treatment time is 5 to 15 fens kinds.
Draping over one's shoulders multiple C type polyphenylene ethyl mould material in TiNi inner support frame surface and be with C type p-Xylol cyclodimerisation body is raw material, feed in the vacuum vessel of vapor phase growing apparatus, in the time of 600-750 ℃, carry out cracking and become active radical monomer, at room temperature be polymerized to C type polyphenylene ethyl material at last.It is that a kind of winding method with TiNi mesh-like support combines with chemical gaseous phase depositing process that the TiNi inner support frame is coated with polymeric membrane technology, its technological process is to select relevant generation raw material, become active free matrix by the chemistry cracking of heating, last repolymerization is a C type polyphenylene ethyl material.Multiple for this floor height molecular film is draped over one's shoulders securely on the network surface, must carry out plasma surface modification to the TiNi silk in advance and handle.
Advantage of the present invention is based on the netted bracket basis of a kind of TiNi alloy, used gas-phase deposition that its rack surface is draped over one's shoulders securely to answer one deck to have the C type parylene film of good blood compatibility and histocompatibility, because the multiple layer that drapes over one's shoulders of this polymeric membrane has only 1 to 2 micron, therefore it has kept the memory characteristic of former TiNi alloy inner support frame fully, deformability, the characteristics of super-elasticity and conformability etc., so the organic assembling method of this material is simple, practical, have certain popularity and versatility, its practicality, easily control also can adapt to quantification production.In addition, method of the present invention can not only be applicable to clinical treatment abdominal surgery portal hypertension and stenosis of bile duct disease, and be applicable to digestive tube too, and urethra, department of eye and carotid artery stenosis disease are down to the clinical treatment of brain surgery, cardiology department or the like various diseases.The realization of this method will promote and widen the clinical application in biomedical sector of former TiNi shape memory alloy greatly.
Description of drawings
Accompanying drawing 1 is a radio-frequency plasma surface modification treatment apparatus structure synoptic diagram of the present invention.
Accompanying drawing 2 is chemical vapor deposition unit major portion structural representations.
In the above accompanying drawing, the 1st, sample chamber, the 2nd, radio-frequency power supply, the 3rd, mechanical pump, the 4th, high vacuum valve, the 5th, fine setting vacuum valve, the 6th, purging valve, the 7th, the rough vacuum resistance vacuum gauge, the 8th, TiNi alloy inner support frame, the 9th, heater coil, the 10th, TiNi alloy inner support frame, the 11st, vacuum vessel, the 12nd, the C type p-Xylol cyclodimerisation body raw material that feeds.
Introduce one embodiment of the present of invention below in conjunction with accompanying drawing.In the present embodiment, adopt the radio-frequency plasma surface modifying treatment that TiNi alloy inner support frame is carried out surface treatment.The concrete structure of radio-frequency plasma surface modification treatment device as shown in Figure 1.Wherein the sample chamber is a bell glass 1, link to each other with mechanical pump 3 by high vacuum valve 4, and the argon gas that 5 controls of fine setting vacuum valve feed, 6 is purging valve, and radio-frequency power supply 2 is a SPD-500 type device, and its rf frequency is 10MHZ, and radio frequency power is that 0-500W is adjustable.The air pressure of system is monitored by rough vacuum resistance vacuum gauge 7.Usually the standard handled of radio-frequency plasma modification is as follows: radio frequency power is 80-100W, and ar pressure is 80 to 300mmHg, and rf frequency is 8 to 12MHZ, and the plasma modification treatment time is 5-15 minute.
The vacuum vessel that TiNi alloy inner support frame that modification handles places chemical vapor deposition unit has been carried out on the surface, with C type p-Xylol cyclodimerisation body is raw material, feed in the vacuum vessel, in the time of 600-750 ℃, carry out cracking and become active radical monomer, at room temperature be polymerized to C type polyphenylene ethyl material at last.This chemical vapor deposition unit primary structure as shown in Figure 2.Wherein 9 is heater coils, the 10th, and TiNi alloy inner support frame, the 11st, vacuum vessel, the 12nd, the C type p-Xylol cyclodimerisation body raw material that feeds.
In the present embodiment, employing is that the radio-frequency plasma modification is handled.In fact modification is handled has three kinds of modes can supply to adopt, i.e. direct-current plasma, radio-frequency plasma, microwave plasma modification handled.The effect that confirms direct-current plasma and radio-frequency plasma modification processing through practice is the same substantially.But if handle single workpiece, the mode that can utilize direct-current plasma to handle as modification; If handle a plurality of workpiece, it is just relatively good then to adopt the radio-frequency plasma modification to handle, and the result is more even for its surface-treated, and effect is also better.Should microwave plasma modification treatment effect better, but at present can only be as a kind of feasible scheme, wherein how waveguide carries, time, range of frequency that modification is handled, also have a key issue is how microwave radiation shields, what institute must consideration when this was follow-up development.
Claims (1)
1, a kind of titanium nickel inner support frame coating process comprises the steps:
The first, adopt radio-frequency plasma mode or direct-current plasma mode or microwave plasma mode that plasma modification is carried out on Ti-Ni alloy inner support frame surface and handle;
The second, adopt chemical vapor deposition method make Ti-Ni alloy inner support frame surface firm drape over one's shoulders multiple last layer C type parylene film; It is characterized in that:
The thickness of C type parylene film is 1 to 2 micron; Adopt in the processing condition that the radio-frequency plasma mode handles Ti-Ni alloy inner support frame surface: radio frequency power is that 80-100W, ar pressure are that 80 to 300 mmhg, rf frequency are 8 to 12MHZ, the plasma modification treatment time is 5 to 15 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00112312 CN1244712C (en) | 2000-06-01 | 2000-06-01 | Coating process for TiNi inner support rack |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00112312 CN1244712C (en) | 2000-06-01 | 2000-06-01 | Coating process for TiNi inner support rack |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1327080A CN1327080A (en) | 2001-12-19 |
| CN1244712C true CN1244712C (en) | 2006-03-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00112312 Expired - Fee Related CN1244712C (en) | 2000-06-01 | 2000-06-01 | Coating process for TiNi inner support rack |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1244712C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10342899B2 (en) * | 2015-12-19 | 2019-07-09 | Cardiac Pacemakers, Inc. | Biologically inert coating for implantable medical devices |
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2000
- 2000-06-01 CN CN 00112312 patent/CN1244712C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1327080A (en) | 2001-12-19 |
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Owner name: NANJING TIANHUILI ENGINEERING CO., LTD. Free format text: FORMER OWNER: YILAI GENE MEDICINE CO., LTD., NANJING Effective date: 20060804 |
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Effective date of registration: 20060804 Address after: Nanjing City, Jiangsu province 210007 Daguang Road No. 47 building 25 floor Hongying Patentee after: Nanjing Huili purification Engineering Co Ltd Address before: Room 503, VIP Building, 6 Taiping Street, Xuanwu District, Jiangsu, Nanjing, Patentee before: Yilai Gene Medical Co. Ltd., Nanjing |
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Owner name: NANJING KAIER INSTRUMENT CO., LTD. Free format text: FORMER OWNER: NANJING TIANHUILI ENGINEERING CO., LTD. Effective date: 20061103 |
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Effective date of registration: 20061103 Address after: Nanjing City, Jiangsu province 210003 Hui Long Qiao No. 10 office building 3 floor Patentee after: Nanjing Kell Instrument Co., Ltd. Address before: Nanjing City, Jiangsu province 210007 Daguang Road No. 47 building 25 floor Hongying Patentee before: Nanjing Huili purification Engineering Co Ltd |
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