CN1242774C - Medicine for curing proliferation arthritis of spine and its preparation method - Google Patents

Medicine for curing proliferation arthritis of spine and its preparation method Download PDF

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CN1242774C
CN1242774C CNB011289767A CN01128976A CN1242774C CN 1242774 C CN1242774 C CN 1242774C CN B011289767 A CNB011289767 A CN B011289767A CN 01128976 A CN01128976 A CN 01128976A CN 1242774 C CN1242774 C CN 1242774C
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radix
rhizoma
medicine
arthritis
medicament
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CN1411829A (en
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宋大文
任相如
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Abstract

The present invention relates to a medicament for treating proliferation arthritis of the vertebral column, which has the technical scheme that natural medicine which has the functions for expelling wind, alleviating pain, dredging the meridian passage, warming the channels, strengthening yang, activating blood circulation, dissipating blood stasis, nourishing the muscle and tendon, strengthening the bones and supplementing essence and blood is selected on the basis of the pathological analysis of proliferative arthritis of the vertebral column in Chinese medicine, and the development of a modern process for preparing medicine, and compound functions are formed by means of a strict traditional Chinese medicine formula. The medicament has special curative effects for curing cervical spondylosis, hyperostosis, ankylosing spondylitis, scoliosis, rachischisis, lumbar sacralization, prolapse of lumbar intervertebral disc, rheumatoid arthritis, arthralgia on the limbs, numbness, later repair of fracture, etc.

Description

Medicine of treatment proliferation arthritis of spine and preparation method thereof
Technical field:
The present invention relates generally to a kind of medicine for the treatment of proliferation arthritis of spine, particularly a kind of is the Chinese patent medicine and preparation method thereof of feedstock production with the Chinese herbal medicine.
Proliferation arthritis of spine is a kind of common multiple pertinacious disease, patient's acroparesthesia, numbness, pain, and obstacle appears in motor function, the normal cervical spondylosis that forms, lumbar vertebra hyperosteogeny, ankylosing spondylitis etc. are from the angle of motherland's medical science, the formation of the above-mentioned cause of disease is because human spine's biomechanics changes, and disequilibrium makes sections dislocation, soft tissue adhesion, meridians are obstructed, coagulation of QI-blood, zang-fu disharmony, skeleton is unusual, substance in vivo disequilibrium coordinative role, thereby suffer from this disease.This disease prevalence in the rural population of China is higher, all is easy to make the people disability of disabling too late as malpractice or treatment, brings great misery to the people.It is more to treat the related types of drugs of this disease at present, but general kind is all more single, and therapeutic domain is narrow, is difficult to integral body after the patient takes and comes into force, so existing medicine is all lower to patient's cure rate.Therefore a kind of medicine that can treat proliferation arthritis of spine effectively is that people expect.
The object of the present invention is to provide a kind of medicament that can cure proliferation arthritis of spine with higher proportion.
Another object of the present invention provides a kind of above-mentioned medicaments preparation method.
Solution of the present invention is based on motherland's medical science to the pathological analysis of proliferation arthritis of spine and in conjunction with the development of modern pharmaceutical technology, filter out the analgesia of to dispel the wind, dredge the meridian passage, warming the meridian tonifying YANG, blood circulation promoting and blood stasis dispelling, the nourishing muscle and tendon bone strengthening, the natural drug of enrich and benefit essence and blood, and, form the compound recipe effect through the Chinese medicine preparation of strictness, to reach the effect of curing above-mentioned disease, medicine of the present invention is made (weight proportion) by following component:
Radix Rehmanniae Preparata 5-15 Herba Cistanches 1-5 Caulis Spatholobi 2-12 Rhizoma Drynariae 1-12
Rhizoma Cibotii 1-5 Herba Epimedii 1-5 Radix Angelicae Sinensis 1-8 Rhizoma Chuanxiong 1-8
Bulbus Fritillariae Thunbergii 1-5 Worm 1-5 Radix Scrophulariae 1-8 Radix Et Rhizoma Rhei 5-14
Radix Astragali 2-10 Radix Notoginseng 1-5 Rhizoma Et Radix Notopterygii 1-5 Radix Angelicae Pubescentis 1-5
Radix Gentianae Macrophyllae 1-5 Zaocys 1-5 Herba Taxilli 1-5 Cortex Eucommiae 1-5
Radix Polygoni Multiflori 1-8 Radix Cyathulae 1-5 Semen Sinapis Albae 5-10 Concha Ostreae 5-15
Ramulus Cinnamomi 1-8 Radix Paeoniae Alba 1-8 corydalis tuber 5-15 Radix Puerariae 3-10.
The weight proportion scope of the formula optimization of preparation medicine of the present invention is:
Radix Rehmanniae Preparata 8-11 Herba Cistanches 1-3 Caulis Spatholobi 5-8 Rhizoma Drynariae 3-9
Rhizoma Cibotii 2-3 Herba Epimedii 2-3 Radix Angelicae Sinensis 3-5 Rhizoma Chuanxiong 3-5
Bulbus Fritillariae Thunbergii 2-3
Figure C0112897600052
Worm 2-3 Radix Scrophulariae 3-5 Radix Et Rhizoma Rhei 8-10
Radix Astragali 5-8 Radix Notoginseng 2-3 Rhizoma Et Radix Notopterygii 2-3 Radix Angelicae Pubescentis 2-3
Radix Gentianae Macrophyllae 2-3 Zaocys 2-3 Herba Taxilli 2-3 Cortex Eucommiae 2-3
Radix Polygoni Multiflori 3-5 Radix Cyathulae 2-3 Semen Sinapis Albae 8-10 Concha Ostreae 8-11
Ramulus Cinnamomi 3-5 Radix Paeoniae Alba 3-5 corydalis tuber 10-13 Radix Puerariae 6-9.
Optimum weight proportioning of the present invention is:
Radix Rehmanniae Preparata 8 Herba Cistanches 1 Caulis Spatholobi 5 Rhizoma Drynariae 3
Rhizoma Cibotii 2 Herba Epimedii 2 Radix Angelicae Sinensis 3 Rhizoma Chuanxiongs 3
Bulbus Fritillariae Thunbergii 2 Worm 2 Radix Scrophulariaes 3 Radix Et Rhizoma Rhei 8
The Radix Astragali 5 Radix Notoginseng 2 Rhizoma Et Radix Notopterygiis 2 Radix Angelicae Pubescentiss 2
Radix Gentianae Macrophyllae 2 Zaocys 2 Herba Taxillis 2 Cortexs Eucommiae 2
The Radix Polygoni Multiflori 3 Radix Cyathulaes 2 Semen Sinapis Albaes 8 Concha Ostreaes 8
Ramulus Cinnamomi 3 Radix Paeoniae Albas 3 corydalis tubers 10 Radix Puerariaes 6.
The method that above-mentioned each component is made medicine of the present invention is:
1, Herba Cistanches being added yellow wine steams to dry thoroughly and is crushed to 120 orders;
2, Rhizoma Drynariae is used the stir-baking with sand scalding for removing the hair of materia medica;
3, Rhizoma Cibotii is scalded with stir-baking with sand, scrape floss removing;
4, will Worm is used the steeping in wine parch;
5, with the parch of Radix Et Rhizoma Rhei steeping in wine;
6, Zaocys is decaptitated cutting, the steeping in wine parch;
7, Cortex Eucommiae cutting saline is fried to fracture of wire;
8, the Radix Polygoni Multiflori, Semen sojae atricolor are boiled together;
9, the Radix Paeoniae Alba is given birth to usefulness summer, winter, wine was fried;
10, corydalis tuber is fried with vinegar;
11, Radix Angelicae Sinensis loess is fried;
12, Radix Rehmanniae Preparata, Caulis Spatholobi, Herba Epimedii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Bulbus Fritillariae Thunbergii, Radix Scrophulariae, the Radix Astragali, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Gentianae Macrophyllae, Herba Taxilli, Radix Cyathulae, Semen Sinapis Albae, Concha Ostreae, Ramulus Cinnamomi, powder of Radix Puerariae are broken to 120 order fine powders.
13, with above-mentioned whole medicament components by after the described mixed, carry out ripening at 100-110 ℃, sterilization treatment 10-30 minute, can obtain the powder medicine.
Powder after the maturation process can be made ball, loose or capsule, to meet patient's the custom of taking by the conventional treatment method of Chinese medicine.
Medicament of the present invention is concluded roughly effect described as follows.
1, medicament of the present invention has the stronger analgesia of dispeling the wind as the medication of treatment proliferation arthritis of spine, dredge the meridian passage, warming the meridian tonifying YANG, the synergism of elements such as increase calcium, phosphorus, ferrum.
2, medicament of the present invention has stronger function of promoting blood circulation to disperse blood clots, can improve the blood circulation ischemic state, improves the connective tissue metabolism, and capillary permeability, promotes the conversion of hypertrophy pathological changes to absorb, and lesion tissue disappears, and makes the connective tissue reparation of atrophy.
3, the compound recipe effect of medicament utilization Chinese herbal medicine of the present invention has stronger nourishing the liver and kidney, tonifying YANG controlling nocturnal emission with astringent drugs, nourishing muscle and tendon bone strengthening, enrich and benefit essence and blood, effects such as opposing virus.
4, medicament of the present invention can be repaired the compensatory stability of joint of vertebral column, improves the articular cartilage platform and destroys the state that degeneration is beneficial to reparation, and alleviating pain improves stiff joint and recovers elastic equilibrium, regains stable pliability.
In view of above-mentioned effect is arranged, medicament of the present invention is mainly to the caused cervical spondylosis of proliferation arthritis of spine, hyperosteogeny, ankylosing spondylitis, scoliosis, spina bifida, lumbar sacralization, prolapse of lumbar intervertebral disc, rheumatoid arthritis, extremities joint pain, numbness, fracture later stage reparation waits disease that special curative effect is arranged.
For showing medicament of the present invention to treating the effect of above-mentioned disease, special work has more careful clinical statistics.Statistics shows, the patient of proliferation arthritis of spine series disease is very general, the area of institute's investigation statistics more than 30 years old men and women 60% suffer from this class disease, taking the photograph sheet through the spinal column X-ray shows, this class patient's neck thoracic vertebra, waist sections, vertebral body stabilising arrangement all have change or little dislocation in various degree, and the man is more than the woman; Other suffer from spinal column Secondary cases neck, and lumbar vertebra hyperosteogeny is tetanic, and sections dislocation is also very common, ill elder 20 years, the shortest person 6 months.
Select 500 examples in above-mentioned patient, wherein some people not only suffers from proliferation arthritis of spine, also is associated with hypertension 183 examples, take medicament of the present invention after, doing well,improving, pain disappears, hyperpietic's blood pressure is normal.After the drug withdrawal, 1 year recidivist's 9 example, 2 years recidivist's 18 examples, 3 years recidivist's 3 examples, and do not have other side effect, show that medicament of the present invention is effective.
Now enumerate the curative effect of some indivedual case explanations medicine of the present invention again.
Case 1, the summer * *, man, 68 years old now, the patient lifts hospital to seek medical advice in August, 90, walks on inspection and walks lamely edema of pair of lower extremities, waist can not be upright, dizzy 2 years of readme, two upper limb, numbness of lower limbs, pain, take the photograph sheet through X-ray and show that cervical vertebral space is narrow, the physiology axis changes, and lumbar spine is stiff, vertebral body is olecranon sample hypertrophy, and intervertebral space disappears, and is diagnosed as neck, hyperosteogeny arthritis, ankylosing spondylitis, hypertension etc.The patient took medicament of the present invention 10 months continuously, and hyperosteogeny is stable, function freely, blood pressure is normal.Follow up a case by regular visits to no longer recurrence so far.
Case 2, female * *, the man, 58 years old, in April, 96, hospital sought medical advice, and waist can not directly rise on inspection, can not walk, and three months causes of private prosecution are lifted precoated plate and are fallen down, and do not heal through local multi-treatment.Through X-ray examination, waist 3,4,5 vertebras are the olecranon sample and change, and intervertebral space disappears, and waist has old compression vertebral fracture damaged.Merge lumbar vertebra old compression fracture for the lumbar spine proliferative arthritis after diagnosing.Fully recover after five months through taking medicament of the present invention continuously, restore funcitons is followed up a case by regular visits to not recurrence again in 5 years.
Case 3, open * *, the man, 48 years old, two numbnesss of lower limbs, pain came hospital to seek medical advice to the patient because of lumbago in April, 96.Patient body is general on inspection, walks and walks lamely, and the back of a bow is bent over, and through X-ray examination waist 1,2,3,4,5 vertebral bodys thorn sample forms, and the olecranon sample changes, and is the lumbar spine proliferative arthritis after diagnosing.Fully recover after four months through taking this medicament, follow up a case by regular visits to 5 not recurrences every year so far.
Above case is unequal to electing.
Embodiment:
Take by weighing material (weight kilogram) by following proportioning:
Radix Rehmanniae Preparata 8 Herba Cistanches 2 Caulis Spatholobis 5 Rhizoma Drynariae 3.5
Rhizoma Cibotii 2 Herba Epimedii 2 Radix Angelicae Sinensis 3.5 Rhizoma Chuanxiongs 3.5
Bulbus Fritillariae Thunbergii 2
Figure C0112897600091
Worm 2 Radix Scrophulariaes 3.5 Radix Et Rhizoma Rhei 0.8
The Radix Astragali 5 Radix Notoginseng 2 Rhizoma Et Radix Notopterygiis 2 Radix Angelicae Pubescentiss 2
Radix Gentianae Macrophyllae 2 Zaocys 2 Herba Taxillis 2 Cortexs Eucommiae 2
The Radix Polygoni Multiflori 3.5 Radix Cyathulaes 2 Semen Sinapis Albaes 0.8 Concha Ostreae 8
Ramulus Cinnamomi 3.5 Radix Paeoniae Albas 3.5 corydalis tubers 10 Radix Puerariaes 6.

Claims (4)

1, a kind of medicine for the treatment of proliferation arthritis of spine is characterized in that: it is the medicament of being made by following weight proportioning raw material,
Radix Rehmanniae Preparata 5-15 Herba Cistanches 1-5 Caulis Spatholobi 2-12 Rhizoma Drynariae 1-12
Rhizoma Cibotii 1-5 Herba Epimedii 1-5 Radix Angelicae Sinensis 1-8 Rhizoma Chuanxiong 1-8
Bulbus Fritillariae Thunbergii 1-5
Figure C011289760002C1
Worm 1-5 Radix Scrophulariae 1-8 Radix Et Rhizoma Rhei 5-14
Radix Astragali 2-10 Radix Notoginseng 1-5 Rhizoma Et Radix Notopterygii 1-5 Radix Angelicae Pubescentis 1-5
Radix Gentianae Macrophyllae 1-5 Zaocys 1-5 Herba Taxilli 1-5 Cortex Eucommiae 1-5
Radix Polygoni Multiflori 1-8 Radix Cyathulae 1-5 Semen Sinapis Albae 5-10 Concha Ostreae 5-15
Ramulus Cinnamomi 1-8 Radix Paeoniae Alba 1-8 corydalis tuber 5-15 Radix Puerariae 3-10.
2, the medicine of treatment proliferation arthritis of spine according to claim 1 is characterized in that: wherein the weight proportion of each raw material is:
Radix Rehmanniae Preparata 8-11 Herba Cistanches 1-3 Caulis Spatholobi 5-8 Rhizoma Drynariae 3-9
Rhizoma Cibotii 2-3 Herba Epimedii 2-3 Radix Angelicae Sinensis 3-5 Rhizoma Chuanxiong 3-5
Bulbus Fritillariae Thunbergii 2-3
Figure C011289760002C2
Worm 2-3 Radix Scrophulariae 3-5 Radix Et Rhizoma Rhei 8-10
Radix Astragali 5-8 Radix Notoginseng 2-3 Rhizoma Et Radix Notopterygii 2-3 Radix Angelicae Pubescentis 2-3
Radix Gentianae Macrophyllae 2-3 Zaocys 2-3 Herba Taxilli 2-3 Cortex Eucommiae 2-3
Radix Polygoni Multiflori 3-5 Radix Cyathulae 2-3 Semen Sinapis Albae 8-10 Concha Ostreae 8-11
Ramulus Cinnamomi 3-5 Radix Paeoniae Alba 3-5 corydalis tuber 10-13 Radix Puerariae 6-9.
3, the medicine of treatment proliferation arthritis of spine according to claim 1 and 2 is characterized in that: said medicament is ball, looses or capsule.
4, the preparation method of the described treatment proliferation arthritis of spine of claim 1 medicine is characterized in that:
(1) Herba Cistanches being added yellow wine steams to dry thoroughly and is crushed to 120 orders;
(2) Rhizoma Drynariae is used the stir-baking with sand scalding for removing the hair of materia medica;
(3) Rhizoma Cibotii is scalded with stir-baking with sand, scrape floss removing;
(4) will Worm is used the steeping in wine parch;
(5) with the parch of Radix Et Rhizoma Rhei steeping in wine;
(6) Zaocys is decaptitated cutting, the steeping in wine parch;
(7) Cortex Eucommiae cutting saline is fried to fracture of wire;
(8) Radix Polygoni Multiflori cutting and Semen sojae atricolor are boiled together;
(9) Radix Paeoniae Alba is given birth to usefulness summer, winter, wine was fried;
(10) corydalis tuber is fried with vinegar;
(11) Radix Angelicae Sinensis loess is fried;
(12) Radix Rehmanniae Preparata, Caulis Spatholobi, Herba Epimedii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Bulbus Fritillariae Thunbergii, Radix Scrophulariae, the Radix Astragali, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Gentianae Macrophyllae, Herba Taxilli, Radix Cyathulae, Semen Sinapis Albae, Concha Ostreae, Ramulus Cinnamomi, powder of Radix Puerariae are broken to 120 order fine powders,
(13) with above-mentioned whole medicament components by after the described mixed, carry out ripening at 100-110 ℃, sterilization treatment 10-30 minute, can obtain the powder medicine.
CNB011289767A 2001-10-17 2001-10-17 Medicine for curing proliferation arthritis of spine and its preparation method Expired - Fee Related CN1242774C (en)

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1301729C (en) * 2003-10-21 2007-02-28 中国人民解放军总医院 Medicine for treating tetanic rachitis and its prepn process
CN100391497C (en) * 2004-02-11 2008-06-04 辽宁中医学院 Nanometer Chinese traditional medicine for treating osteoporosis
CN101926878B (en) * 2010-06-03 2014-10-29 陕西中医学院 Chinese medicinal composition for treating osteoarthritis and preparation method thereof
CN104606409B (en) * 2015-01-06 2018-06-22 张贵堂 A kind of drug for treating osteoarthritis and preparation method thereof
CN107174640A (en) * 2016-03-10 2017-09-19 杨甫进 Chinese medicine preparation for treating degenerative osteoarthropathy and preparation method thereof
CN107349400A (en) * 2017-07-03 2017-11-17 南宁市共健源健康科技有限公司 A kind of Chinese medicine composition for treating ankylosing spondylitis and preparation method thereof

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