CN1219049C - 无菌隔离操作*** - Google Patents
无菌隔离操作*** Download PDFInfo
- Publication number
- CN1219049C CN1219049C CN 02111538 CN02111538A CN1219049C CN 1219049 C CN1219049 C CN 1219049C CN 02111538 CN02111538 CN 02111538 CN 02111538 A CN02111538 A CN 02111538A CN 1219049 C CN1219049 C CN 1219049C
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- Prior art keywords
- bacteria
- wedge
- cabin
- free
- aseptic
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000012546 transfer Methods 0.000 claims abstract description 58
- 238000002474 experimental method Methods 0.000 claims abstract description 30
- 230000005540 biological transmission Effects 0.000 claims description 19
- 230000001954 sterilising effect Effects 0.000 claims description 17
- 238000004659 sterilization and disinfection Methods 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 7
- 239000000645 desinfectant Substances 0.000 claims description 6
- 238000000889 atomisation Methods 0.000 claims description 4
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 230000007246 mechanism Effects 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 abstract description 6
- 238000002360 preparation method Methods 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 2
- 238000010276 construction Methods 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 12
- 238000000746 purification Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 210000001503 joint Anatomy 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 230000009970 fire resistant effect Effects 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Images
Landscapes
- Apparatus For Disinfection Or Sterilisation (AREA)
- Housing For Livestock And Birds (AREA)
Abstract
Description
项目 | 传统无菌室 | 本发明*** |
对产品的防护程度 | 与操作人员有关 | 完全防护 |
对操作人员的防护程度 | 与操作人员有关 | 完全防护 |
所需能耗 | 大 | 小 |
物料传递 | 会导致无菌环境变差,并与操作人员有关 | 保证在无菌条件下快速传递 |
设备变动 | 无菌室是长期的,空间完全被占用 | 易于移装且与外部环境无关 |
误操作导致无菌条件破坏的可能性 | 取决于操作人员的技术和培训程度 | 可能性极小 |
灭菌方法 | 整个房间消毒 | 全封闭自动灭菌 |
工作环境的控制 | 难以控制 | 可在全过程中恒定最佳操作环境(温度、湿度、压力) |
工作服的更换 | 每天至少三次 | 无 |
操作和维护成本 | 高 | 低 |
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 02111538 CN1219049C (zh) | 2002-04-26 | 2002-04-26 | 无菌隔离操作*** |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 02111538 CN1219049C (zh) | 2002-04-26 | 2002-04-26 | 无菌隔离操作*** |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1453352A CN1453352A (zh) | 2003-11-05 |
CN1219049C true CN1219049C (zh) | 2005-09-14 |
Family
ID=29256816
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 02111538 Expired - Fee Related CN1219049C (zh) | 2002-04-26 | 2002-04-26 | 无菌隔离操作*** |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1219049C (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101961294A (zh) * | 2010-09-06 | 2011-02-02 | 上海东富龙科技股份有限公司 | 一种冻干制剂核心区域无菌隔离器 |
WO2012098931A1 (ja) * | 2011-01-17 | 2012-07-26 | 学校法人東京女子医科大学 | 細胞培養処理システム及び細胞培養処理システムのモジュール接続方法 |
JP5664967B2 (ja) * | 2011-01-19 | 2015-02-04 | 澁谷工業株式会社 | 無菌接続装置 |
CN102328317A (zh) * | 2011-09-08 | 2012-01-25 | 杭州泰林生物技术设备有限公司 | 一种软舱体隔离器 |
CN103008034A (zh) * | 2011-09-26 | 2013-04-03 | 上海力申科学仪器有限公司 | 培养箱培养物品放置和取出的方法 |
CN103018069A (zh) * | 2011-09-26 | 2013-04-03 | 上海力申科学仪器有限公司 | 培养箱样品取出方法 |
CN102827772B (zh) * | 2012-09-06 | 2014-04-23 | 杭州泰林生物技术设备有限公司 | 一种培养基浇碟方法及其装置 |
CN103961728B (zh) * | 2014-05-08 | 2017-01-11 | 苏州大学 | P3级生物安全柜污染物转移消毒装置 |
CN104758973A (zh) * | 2015-04-03 | 2015-07-08 | 杭州泰林生物技术设备有限公司 | 一种隔离器 |
CN104984772A (zh) * | 2015-06-25 | 2015-10-21 | 中国人民解放军军事医学科学院卫生装备研究所 | 一种便携式生物安全检验隔离装置 |
CN106016978A (zh) * | 2016-07-06 | 2016-10-12 | 山东新华医疗器械股份有限公司 | 实验室用药品无菌冻干隔离器*** |
CN108496831A (zh) * | 2017-02-27 | 2018-09-07 | 苏州市苏杭科技器材有限公司 | 实验动物操作设备无菌连接装置 |
CN106926461A (zh) * | 2017-04-27 | 2017-07-07 | 重庆英泰帝克科技有限公司 | 一种医疗3d无菌打印生产线 |
CN109109025A (zh) * | 2017-06-26 | 2019-01-01 | 天津大学 | 一种简易厌氧操作箱 |
CN107828650B (zh) * | 2017-09-21 | 2020-11-24 | 浙江泰林生物技术股份有限公司 | 一种细胞免疫治疗工作站 |
CN107801638A (zh) * | 2017-11-02 | 2018-03-16 | 深圳市前海金卓生物技术有限公司 | 一种无菌动物运输器 |
CN111472582B (zh) * | 2020-06-23 | 2020-11-10 | 深圳市亚纪星科技有限公司 | 病原体检测***以及病原体的转移方法 |
CN113462563B (zh) * | 2021-06-24 | 2022-12-27 | 冰山松洋生物科技(大连)有限公司 | 一种基于细胞工作站与采集室联通的无菌传递*** |
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2002
- 2002-04-26 CN CN 02111538 patent/CN1219049C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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CN1453352A (zh) | 2003-11-05 |
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Addressee: Tang Xun Document name: Notice of conformity |
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EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Hangzhou Tailin Biotechnology Equipment Co., Ltd. Assignor: Ye Dalin Contract fulfillment period: 2008.8.20 to 2015.8.19 Contract record no.: 2008330000385 Denomination of invention: Bacteria-free isolated operation system Granted publication date: 20050914 License type: Exclusive license Record date: 20080908 |
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LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENCE; TIME LIMIT OF IMPLEMENTING CONTACT: 2008.8.20 TO 2015.8.19 Name of requester: HANGZHOU TAILIN BIOTECHNOLOGY EQUIPMENT CO., LTD. Effective date: 20080908 |
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Owner name: ZHEJIANG TAILIN BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: YE DALIN Effective date: 20150731 |
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Effective date of registration: 20150731 Address after: 310052 Binjiang District, Zhejiang, South Ring Road, No. 2930, No. Patentee after: ZHEJIANG TAILIN BIOENGINEERING CO., LTD. Address before: 310013 -1601 building, B building, Kang Xin Garden, No. 569, Wensanlu Road, Zhejiang, Hangzhou Patentee before: Ye Dalin |
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Granted publication date: 20050914 Termination date: 20190426 |