Gubenhuiyuan Chinese Medicinal Composition And Manufacturing Approach of Oral Liquid
Technical field
The present invention relates to a kind of medicine and manufacture method thereof that consolidates back meta function that have, relate in particular to a kind of Gubenhuiyuan Chinese Medicinal Composition And Manufacturing Approach of Oral Liquid.
Background technology
After people in middle age, metabolism, every physiological function such as digest and assimilate and begin to go down, insufficiency of vital energy and blood, energy, muscle power, intelligence begin to glide; Enter old age, cell and organ atrophy are degenerated and are further aggravated, and every physiological function fails comprehensively, and asthenia of qi and blood declines, immunocompromised, and various dysfunctions and senile disease are comed one after another.Statistics shows that suffering from a deficiency of the kidney with senile disease is old people's two threats greatly.Along with the quickening of people's lives rhythm and the increase of pressure, a lot of people are in sub-health state.
The traditional Chinese medical science is thought: the kidney being the origin of congenital constitution, first of the five internal organs, dominate and regulate and control growth, growth and the reproduction of human body, and influence the function of systems such as endocrine, metabolism, breathing, blood, circulation, digestion, urinary system, audition, hair, defecation and organ by the mutual generation of five phases restriction or checking relation in five elements, be the life the source of vital function; The spleen and stomach provide the material basis of the acquired, and digest and assimilate essence of water and grain and supply with the necessary nutrition elite of health, be source of generating QI and blood.Therefore, the taste in the source of the kidney of Source of life and QI and blood are considered to the basic of life jointly.Consolidate, by kidney and taste are maintained and nurse one's health, the solid life of reinforcement and training is basic exactly, and the regulating and controlling effect by kidney and hormonal system, improve metabolism, the function of each histoorgan of whole body is provided comprehensively, make cell activation, organ youth, life dynamic.
The traditional Chinese medical science is also thought: kidney storing essence, and the congenital essence of hiding derives from father and mother's hereditary elite, is base substance and the original power that constitutes life; Acquired essence derives from the nutrition elite that taste are digested and assimilated; Earlier, acquired essence is the basic assurance that human body growth promoter and life obtain.The biochemical blood of smart energy, body fluid and vigour, each histoorgan of whole body is moistened in nutrition.And vigour is to promote the active fundamental driving force of all tissue organ functions, is the basic of immunity of organism defence reparative regeneration.Vigour is filled Sheng, and each tissue organ function of health is normal, immune repair ability prosperity.Hui Yuan, replenish by kidney and spleen invigorating exactly and rebuild one's physical constitution, healthy energy, enhance immunity provides total quality, makes healthy few sick, life lengthening.
Consolidate back primordial oral liquid and acted on Chinese nation's marrow of Chinese medicine over the past thousands of years.According to Traditional Chinese medical theory, the effect of its main component is respectively:
Radix Ginseng (radix Ginseng): strongly invigorating primordial QI, with promoting generation of vital essence and blood, invigorating the spleen to benefit the lung, promoting the production of body fluid and inducing sedation of the mind, enhance immunity.
The Radix Astragali (Radix Astragali): air making-up and spleen enlivening, the yang invigorating consolidating superficial resistance, diuresis is invigorated blood circulation, and can protect the liver, bring high blood pressure down, improve circulation.
Radix Notoginseng (Radix Notoginseng): enrich blood the first, give birth to dissipating blood stasis treating blood disorders, reducing swelling and alleviating pain, ripe in blood nourishing body building, allaying tiredness, but heart tonifying, blood fat reducing, antiinflammatory sterilization, regulate immunity.
Radix Angelicae Sinensis (Radix Angelicae Sinensis): enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, but blood fat reducing blood pressure lowering.
Radix Polygoni Multiflori (Radix Polygoni Multiflori): invigorating the liver and kidney, benefiting essence-blood, controlling nocturnal emission with astringent drugs end to be lost, and black hair makes eye bright, loosening bowel to relieve constipation.
Fructus Lycii (Fructus Lycli): nourishing the liver and kidney, enrich and benefit essence and blood, black hair makes eye bright, and replenishes several amino acids, vitamin and trace element.
Radix Rehmanniae Preparata (Radix Rehmanniae Preparata): nourishing YIN and supplementing blood, beneficial essence is filled out marrow, energy heart tonifying, diuresis, blood pressure lowering, blood sugar lowering.
Hippocampus (Hippocampus): the big very unit of mending, big benefit is deficient, and warm refreshing tonifying YANG provides multiple high-quality animal proteinum, vegetable protein and aminoacid.
Herba Cistanches (Herba Cistanches): warming and recuperating the kidney-YANG, enrich and benefit essence and blood, loosening bowel to relieve constipation, blood pressure lowering.
Herba Epimedii (Herba Epimedii): the kidney invigorating liver, bone and muscle strengthening, wind-damp dispelling can blood pressure lowering, blood sugar lowering, promotes gonepoiesis, enhance immunity and hypoxia-bearing capability.
Semen Astragali Complanati (Semen Astragali Complanati): temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs reducing urination.
Semen Cuscutae (Semen Cuscutae): the temperature compensation Liver and kidney, controlling nocturnal emission with astringent drugs on-slip, the astringing QI reducing urination, the antidiarrheal that makes eye bright can be used for heart tonifying, blood pressure lowering, control miscarriage, premature labor.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition that consolidates back meta function that has, it is made up of following raw materials according or is made as active component and selectable pharmaceutically acceptable additives by the water and/or the ethanol extraction of following raw materials according:
Radix Ginseng 2-4 weight portion, Radix Notoginseng 1-3 weight portion, Radix Astragali 2-5 weight portion, Radix Rehmanniae Preparata 3-7 weight portion, Radix Angelicae Sinensis 2-5 weight portion, Fructus Lycii 3-7 weight portion, Herba Cistanches 3-7 weight portion, Radix Polygoni Multiflori 3-7 weight portion, Radix Achyranthis Bidentatae (Radix Achyranthis Bidentatae) 2-5 weight portion, Semen Cuscutae 3-7 weight portion, Herba Cynomorii (Herba Cynomorii) 3-7 weight portion, Rhizoma Curculiginis (Rhizoma Curculiginis) 2-4 weight portion, the Cortex Eucommiae (CortexEucornmiae) 2-5 weight portion, Semen Astragali Complanati 2-5 weight portion, Fructus Corni (Fructus Corni) 2-5 weight portion, Fructus Cnidii (Frucctus Cnidii) 2-5 weight portion, Herba Epimedii 3-7 weight portion, Fructus Psoraleae (Fructus Psoraleae) 3-7 weight portion, Actinolitum (Tremolitum) 3-7 weight portion, Semen Allii Tuberosi (Semen Allii Tuberosi) 2-5 weight portion, Radix Morindae Officinalis (RadixMorindae Officinalis) 2-5 weight portion, Fructus Ligustri Lucidi (Fructus Ligustri Lucidi) 3-7 weight portion, Hippocampus 0.5-2 weight portion, Flos Caryophylli (Flos Caryophylli) 1-3 weight portion, Fructus Jujubae (Fructus Jubae) 2-5 weight portion, Flos Chrysanthemi (Flos Chrysanthemi) 2-5 weight portion, Radix Glycyrrhizae Preparata (Radix Glycyrrhizae Preparata) 3-7 weight portion.
Another object of the present invention provides the method that a kind of preparation has the Chinese medicine composition oral liquid that consolidates back meta function, and it may further comprise the steps:
(1) gets Radix Ginseng, Radix Notoginseng, Fructus Ligustri Lucidi, Semen Allii Tuberosi, Fructus Cnidii, Flos Caryophylli, Fructus Psoraleae and be ground into coarse powder;
(2) all the other 20 flavor medicines such as coarse powder and Radix Angelicae Sinensis, Radix Achyranthis Bidentatae etc. are mixed, place extraction pot, add immersion and flood, start agitator then and intermittently stir a couple of days with motor stirrer.
(3) divide and to get impregnation liquid, filter, in medicinal liquid, add Mel and regulate taste, and add water and be adjusted to appropriate amount, stir evenly, leave standstill.
(4) use filtering with microporous membrane, packing gets product.
Of the present inventionly consolidate back the marrow that primordial oral liquid has acted on Chinese Chinese medicine, have effects such as YIN nourishing and YANG strengthening, QI invigorating hyperemia, life essence-filling, marrow-benefitting, bone and muscle strengthening, controlling nocturnal emission with astringent drugs reducing urination.Cure mainly by physical function decline, root " basis " and lose the various symptoms that void, insufficiency of vital energy and blood cause, especially soreness of waist and knee joint, insomnia forgetfulness, nocturia, tired, dizziness and tinnitus, coldness of the body with chills, numb limbs and tense tendons etc. are had special efficacy.
The specific embodiment
The following examples will be further explained the present invention, but the present invention is not limited only to these embodiment, the scope that these embodiment do not limit the present invention in any way.Some change that those skilled in the art has done within the scope of the claims and adjust also should be thought and belongs to scope of the present invention.
Embodiment 1
(1) take by weighing Chinese crude drug respectively as raw material according to following amount:
Radix Ginseng 3g, Radix Notoginseng 2g, Radix Astragali 4g, Radix Rehmanniae Preparata 5g, Radix Angelicae Sinensis 4g, Fructus Lycii 5g, Herba Cistanches 5g, Radix Polygoni Multiflori 5g, Radix Achyranthis Bidentatae 4g, Semen Cuscutae 5g, Herba Cynomorii 5g, Rhizoma Curculiginis 3g, Cortex Eucommiae 4g, Semen Astragali Complanati 3.5g, Fructus Corni 4g, Fructus Cnidii 4g, Herba Epimedii 5g, Fructus Psoraleae 5g, Actinolitum 5g, Semen Allii Tuberosi 4g, Radix Morindae Officinalis 4g, Fructus Ligustri Lucidi 5g, Hippocampus 1g, Flos Caryophylli 2g, Fructus Jujubae 4g, Flos Chrysanthemi 4g, Radix Glycyrrhizae Preparata 2g;
(2) get Radix Ginseng, Radix Notoginseng, Fructus Ligustri Lucidi, Semen Allii Tuberosi, Fructus Cnidii, Flos Caryophylli, Fructus Psoraleae and be ground into coarse powder;
(3) coarse powder is mixed with all the other 20 flavor Chinese medicines, place extraction pot, added 25% alcohol dipping 6 days, start agitator then and intermittently stirred 3 days, regularly stir each 2 hours every day 4 times with motor stirrer.
(4) divide and to get impregnation liquid, filter, in medicinal liquid, add Mel 125g and regulate taste, and add water and be adjusted to 1000ml, stir evenly, left standstill 24 hours.
(5) filter with microporous filter membrane (aperture 0.2 μ m), packing promptly gets brown supernatant liquid; Its feeble QI perfume (or spice), sweet, little hardship of distinguishing the flavor of.
Embodiment 2
(1) take by weighing Chinese crude drug respectively as raw material according to following amount:
Radix Ginseng 2g, Radix Notoginseng 1g, Radix Astragali 2g, Radix Rehmanniae Preparata 3g, Radix Angelicae Sinensis 2g, Fructus Lycii 3g, Herba Cistanches 3g, Radix Polygoni Multiflori 3g, Radix Achyranthis Bidentatae 2g, Semen Cuscutae 3g, Herba Cynomorii 3g, Rhizoma Curculiginis 2g, Cortex Eucommiae 2g, Semen Astragali Complanati 2g, Fructus Corni 2g, Fructus Cnidii 5g, Herba Epimedii 7g, Fructus Psoraleae 7g, Actinolitum 7g, Semen Allii Tuberosi 5g, Radix Morindae Officinalis 5g, Fructus Ligustri Lucidi 7g, Hippocampus 2g, Flos Caryophylli 3g, Fructus Jujubae 5g, Flos Chrysanthemi 5g, Radix Glycyrrhizae Preparata 7g;
(2) get Radix Ginseng, Radix Notoginseng, Fructus Ligustri Lucidi, Semen Allii Tuberosi, Fructus Cnidii, Flos Caryophylli, Fructus Psoraleae and be ground into coarse powder;
(3) coarse powder is mixed with all the other 20 flavor Chinese medicines, place extraction pot, added 50% alcohol dipping 4 days, start agitator then and intermittently stirred 4 days, regularly stir each 3 hours every day 3 times with motor stirrer.
(4) divide and to get impregnation liquid, filter, in medicinal liquid, add Mel 110g and regulate taste, and add water and be adjusted to 1000ml, stir evenly, left standstill 24 hours.
(5) filter with microporous filter membrane (aperture 0.2 μ m), packing promptly gets brown supernatant liquid; Its feeble QI perfume (or spice), sweet, little hardship of distinguishing the flavor of.
Embodiment 3
(1) take by weighing Chinese crude drug respectively as raw material according to following amount:
Radix Ginseng 4g, Radix Notoginseng 3g, Radix Astragali 5g, Radix Rehmanniae Preparata 7g, Radix Angelicae Sinensis 5g, Fructus Lycii 7g, Herba Cistanches 7g, Radix Polygoni Multiflori 7g, Radix Achyranthis Bidentatae 5g, Semen Cuscutae 7g, Herba Cynomorii 7g, Rhizoma Curculiginis 3g, Cortex Eucommiae 2g, Semen Astragali Complanati 2g, Fructus Corni 2g, Fructus Cnidii 2.5g, Herba Epimedii 3g, Fructus Psoraleae 3g, Actinolitum 3g, Semen Allii Tuberosi 2g, Radix Morindae Officinalis 2g, Fructus Ligustri Lucidi 3g, Hippocampus 0.5g, Flos Caryophylli 1g, Fructus Jujubae 2g, Flos Chrysanthemi 2g, Radix Glycyrrhizae Preparata 3g;
(2) get Radix Ginseng, Radix Notoginseng, Fructus Ligustri Lucidi, Semen Allii Tuberosi, Fructus Cnidii, Flos Caryophylli, Fructus Psoraleae and be ground into coarse powder;
(3) coarse powder is mixed with all the other 20 flavor Chinese medicines, place extraction pot, added 10% alcohol dipping 5 days, start agitator then and intermittently stirred 3 days, regularly stir each 2 hours every day 5 times with motor stirrer.
(4) divide and to get impregnation liquid, filter, in medicinal liquid, add Mel 130g and regulate taste, and add water and be adjusted to 1000ml, stir evenly, left standstill 24 hours.
(5) filter with microporous filter membrane (aperture 0.2 μ m), packing promptly gets brown supernatant liquid; Its feeble QI perfume (or spice), sweet, little hardship of distinguishing the flavor of.
Consolidate back primordial oral liquid according to the described scheme preparation of above 3 groups of embodiment, their clinical efficacy does not have notable difference.Clinical effectiveness shows, the total effective rate of treatment dizziness and tinnitus is 96.3%, treating tired total effective rate is 91.7%, the total effective rate of treatment pain in the low back and legs is 93.1%, the total effective rate of treatment coldness of the body with chills is 98.0%, the total effective rate of treatment hyposexuality is 90.5%, and the total effective rate of treatment nocturia is 99.4%, and the forgetful total effective rate of Cure for insomnia is 88.7%.National Drug Administration to the authentication code of this product is: the accurate word B20020455 of traditional Chinese medicines.