CN1211095C - Blood pressure lowering and heart protecting tablet and its production process - Google Patents

Blood pressure lowering and heart protecting tablet and its production process Download PDF

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Publication number
CN1211095C
CN1211095C CN 00117531 CN00117531A CN1211095C CN 1211095 C CN1211095 C CN 1211095C CN 00117531 CN00117531 CN 00117531 CN 00117531 A CN00117531 A CN 00117531A CN 1211095 C CN1211095 C CN 1211095C
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China
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blood pressure
pressure lowering
radix
hericium
medicine
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Expired - Fee Related
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CN 00117531
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CN1349798A (en
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张友生
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FUSHOUXIAN PHARMACEUTICAL Co Ltd GUANGZHOU
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FUSHOUXIAN PHARMACEUTICAL Co Ltd GUANGZHOU
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Abstract

The present invention relates to a blood pressure lowering and heart protecting tablet which is composed of tuber fleeceflower root, radix notoginseng, pilose asiabell root, shiitake fungus, tremella, indian buead, red sage root, hemlock parsley, angelica, hawthorn fruit, liquoric root, calcium carbonate, magnesium stearate and hericium related by ZL 88100118. X. The thirteen raw materials are divided into three formulas A, B and C as medicine bases, hericium is inoculated and hypha is crushed into medicinal powder to be spare after growing and overspreading; the raw materials of the formula B are extracted into concentrated solution to be spare; the powdery raw materials of the formula A and the formula C are uniformly blended and stirred, then are added into medicinal liquor B to be mixed into dry materials, and the dry materials are crushed into plain tablets which are dried and packaged. The blood pressure lowering and heart protecting tablet produced by the technology of the present invention contains various kinds of fungus polyhexose, flavonoid saponin classes, trace elements, vegetable proteins and calcium elements. Thus, the blood pressure lowering and heart protecting tablet can decrease blood fat and blood pressure of human bodies of persons in middle and old age and can prevent cardiovascular and cerebrovascular diseases.

Description

A kind of tablet of blood pressure lowering and heart protecting
Technical field
A kind of tablet of blood pressure lowering and heart protecting relates to a kind of dietetic therapy food of middle-aged and elderly people.
Background technology
Middle-aged and elderly people is because the immunologic function decline, the organ aging, and irrational diet style or unsound life style, add the harm of environmental pollution and viral pathogenic bacteria, easily cause the generation of flu, asthma, emphysema, pulmonary heart disease and cardiovascular and cerebrovascular disease, cause serious threat for the health of middle-aged and elderly people.Though it is a lot of to treat these sick medicines of planting at present, but it is less to be used for preventative edible health care product, particularly have the incidence rate that to slow down cardiovascular and cerebrovascular disease, postpone the generation age of this disease, can prevent the health food of respiratory system disease not have substantially again.
Summary of the invention
Purpose of the present invention is to provide a kind of dietetic therapy food that is used for middle-aged and elderly people, and both the incidence rate that can make the user slow down cardiovascular and cerebrovascular disease improved the age that cardiovascular and cerebrovascular disease takes place, and can improve immunity again, increased the prevention that respiratory system disease is taken place.
The tablet of the said a kind of blood pressure lowering and heart protecting of the present invention, be to make: at first extract Radix Polygoni Multiflori 8% according to weight ratio with following method, Lentinus Edodes 8%, Tremella 5.8%, Poria 6%, Radix Notoginseng 8%, Radix Codonopsis 8% amount of getting, select, pulverize, after the drinking water that added 1: 1 is mixed thoroughly, with in every bottle of 0.07 kilogram of wide mouthed bottle of packing into as Chinese medicine medicine base, place sterilizing pan then, with 121 ℃ of high-temperature sterilization sterilizations 2 hours, move to after the cooling in the aseptic inoculation chamber, (CGMCC0132) strain of edible meat fungus with the said Basidiomycetes of ZL88100118.X patent (Basidiomycetes) Aphyllophorales (Aphyllophorales) hedgehog hydnum Cordycepps (Hericiaceae) Hericium (Hericium) inserts in the above-mentioned Chinese medicine medicine base, placing temperature is 22~27 ℃, humidity is 65~70% biological engineering cultivation workshop, cultivate after 20~25 days, taking-up is covered with the medicine base of hericium mycelium, be cut into fragment, place vacuum desiccator, after the drying, it is standby to be ground into medicated powder in ultrafine crusher in 70 ℃ low temperature; Select, wash the back merging according to weight ratio extraction Radix Salviae Miltiorrhizae 17%, Rhizoma Chuanxiong 12%, Radix Angelicae Sinensis 8%, Fructus Crataegi 9%, Radix Glycyrrhizae 5% amount of getting again and put into the Chinese medicine extraction jar, the pure water that adds 5 times of raw material weights, decoct 2 hours, pour out medicinal liquid, the pure water that adds 2.5 times of raw material weights more respectively for twice, pour out medicinal liquid after respectively decocting 1 hour, the medicinal liquid of pouring out for three times merged to filter be placed in the medicinal liquid concentration pan, obtaining at 1: 1 in temperature by the dried medicine weight of raw material is that 60~80 ℃, heat survey proportion are 1: 1.18 o'clock water extracting liquid; The medicated powder that (a) technology is obtained, the water extracting liquid that (b) technology obtains; add by weight again calcium carbonate 5%, magnesium stearate 0.2% merge pour into stir in the blender after; place automatic mixer-granulator to make granule; being dried to moisture content in 70 ℃ of low temperature is ± 5%, places automatic tableting press to make plain sheet then.
According to " record and the evidence of Chinese pharmacopoeia and documents such as " pharmacognosy ":
Radix Notoginseng: the dry root of panax araliaceae plant, contain total Saponin 12%, and chemical analysis such as arasaponin, Radix Notoginseng flavone, B-sitosterol, can the dissipating blood stasis hemostasis, subduing swelling and relieving pain, coronary blood flow increasing, blood fat brings high blood pressure down.
Radix Angelicae Sinensis: the root of umbelliferae angelica contains volatile oil and water-soluble components.Volatile oil content is 0.4%, is mainly the n-butene lactone; Water-soluble components has ferulic acid, succinic acid, nicotinic acid etc.Main effect is invigorated blood circulation for enriching blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation, can reduce effects such as vascular resistance, blood flow increasing and arrhythmia.
Rhizoma Chuanxiong: the dry rhizome of samphire Rhizoma Chuanxiong, Main Ingredients and Appearance are interior lipid, alkaloids and phenolic compound, as Rhizoma Chuanxiong lactone, ligustrazine, chuanxingol, ferulic acid etc.Energy blood-activating and qi-promoting, timid wind pain relieving, promotion microcirculation, increase coronary flow etc.
Radix Polygoni Multiflori: be the dry root piece of polygonum multiflorum thunb.Main Ingredients and Appearance is materials such as lecithin, anthraquinone derivative, glycoside, cachou extract.Main effect is invigorating the liver and kidney, benefiting essence-blood, black beard and hair, strengthening bone and muscle, and the energy cholesterol reducing alleviates atherosclerosis.
Radix Salviae Miltiorrhizae: the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.Mainly contain materials such as TANSHINONES, cryptotanshinone, danshensu, vitamin E, cupreol.Energy promoting blood flow to regulate menstruation, blood stasis removing pain relieving, tranquilizing by nourishing the heart, coronary artery dilator, blood flow increasing has blood pressure lowering, blood sugar lowering effect.
Radix Codonopsis: the dry root of campanulaceae plant Radix Codonopsis.Mainly contain bioactive substances such as triterpenoid compound, Saponin, sterol, inulin, fructose, aminoacid.Have antiinflammatory, analgesia, blood pressure lowering and raise immunity effect, energy invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.
Fructus Crataegi: the rosaceous plant Fructus Pyri Pashiae, have promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, blood fat reducing, blood pressure promote steatolysis, increase effects such as coronary blood flow quantity.
Lentinus Edodes: Basidiomycetes Agaricaceae fungus has immunomodulating, antiviral, infection, antitumor and functions of lowering blood-fat and reducing weight.
Tremella: Basidiomycetes Tremellaceae fungus has nourishing YIN and moistening the lung, enhance immunity and the effect of blood fat reducing blood glucose.
Poria: the Polyporaceae fungus has the effect of promoting diuresis to eliminate damp pathogen, invigorating spleen and relieving mental stress and beauty treatment.
Radix Glycyrrhizae: the leguminous plant rhizome has the effect of heat-clearing and toxic substances removing, eliminating phlegm and stopping cough, coordinating the actions of various ingredients in a prescription.
Hericium erinaceus (Bull. Ex Fr.) Pers.: (CGMCC0132) strain of the edible meat fungus of the described Basidiomycetes of ZL88100118.X patent (Basidiomycetes) Aphyllophorales (Aphyllophorales) hedgehog hydnum Cordycepps (Hericiaceae) Hericium (Hericium), its Hericium erinaceus (Bull. Ex Fr.) Pers. Polysaccharides has the effect of better immunity, antiviral, antitumor, anti-radiation and lowering blood-fat and reducing weight, control gastric ulcer than other basidiomycetes polysaccharide.
The specific embodiment
Below, in conjunction with the embodiments in detail, the present invention is described in detail:
Embodiment one:
1, by weight claiming to select 8 kilograms of Radix Notoginseng, 8 kilograms of Radix Polygoni Multiflori, 8 kilograms on Lentinus Edodes, 8 kilograms of Radix Codonopsis, 6 kilograms in 5.8 kilograms in Tremella and Poria, with pulverizer above-mentioned 6 flavor raw material pulverizing mixings after, add drinking water 44kg in 1: 1 ratio, after stirring all, packing into every bottle of 0.07 kilogram of amount, to make the medicine base in the big mouthful vial stand-by;
The wide mouthed bottle of filling the medicine base is placed sterilizing pan, with 121 ℃ high-temperature sterilization sterilizations 2 hours, to kill all antibacterial and assorted bacterium in raw material.Move to after the cooling in the aseptic inoculation chamber, (CGMCC0132) strain of edible meat fungus with the said Basidiomycetes of ZL88100118.X patent (Basidiomycetes) Aphyllophorales (Aphyllophorales) hedgehog hydnum Cordycepps (Hericiaceae) Hericium (Hericium), insert in the above-mentioned Chinese medicine medicine base, in temperature is 22-27 ℃, humidity is 65~70% biological engineering cultivation workshop, cultivate after 20~25 days, taking-up is covered with the medicine matrix of hericium mycelium, being cut into fragment is positioned in the vacuum desiccator, after the drying, it is standby in ultrafine crusher 43.8kg medicine original washing powder to be broken into medicated powder in 70 ℃ low temperature;
2, weigh up 17 kilograms of Radix Salviae Miltiorrhizaes by weight, 12 kilograms of Rhizoma Chuanxiongs, 8 kilograms of Radix Angelicae Sinensis, 9 kilograms of Fructus Crataegis, after 5 kilograms in Radix Glycyrrhizae selects, clean with clear water, merge then and put into the Chinese medicine extraction jar, by water: siccative is to add 255 kilograms of pure water at 5: 1, after decocting 2 hours, pour out medicinal liquid, add 127.5 kilograms of pure water again and decoct 1 hour, pour out medicinal liquid again, add 127.5 kilograms of pure water at last again and decoct 1 hour and pour out medicinal liquid, to make water extracting liquid standby by with former siccative weight 1: 1 medicinal liquid being concentrated into 51 kilograms (are that to survey proportions be 1: 1.18 to 60~80 ℃ of intermittent fever in temperature) to merge the medicinal liquid poured out for three times;
3, extract 5 kilograms of calcium carbonate, 0.2 kilogram of magnesium stearate according to weight ratio; merge to pour in the blender with 43.8kg medicine base medicated powder and stir; pour water extracting liquid 51kg again into; place automatic mixer-granulator to make granule; being dried to moisture content in 70 ℃ low temperature is ± 5%, places automatic tableting press to make plain sheet then.
Embodiment two:
After finishing as front embodiment one pelletization in said early stage, can also be the tablet of the blood pressure lowering and heart protecting that is pressed into qualified plain sheet, place the film coating machine to carry out coating after, check, chip select packing warehouse-in.
Adopted the tablet of a kind of blood pressure lowering and heart protecting that the said method of the present invention makes, owing to adopt multiple eating fungus polysaccharide to combine, and with high-new biotechnology and traditional Chinese herbal medicine compatibility again, make the abundant multiple fungus polysaccharide class in 13 kinds of rare Chinese medicines, flavonoid trace element and vegetable protein, multivitamin with enrich calcium constituent and cooperate, can reduce the intravital blood fat of middle-aged and elderly people, blood pressure, the appropriateness coronary artery dilator, blood flow increasing, to prevention cardiovascular and cerebrovascular disease, good result is arranged, can also improve user's immunity, preventing cold, asthma, pulmonary heart disease, apoplexy and myocardial infarction have good effect.

Claims (2)

1, a kind of tablet of blood pressure lowering and heart protecting is characterized in that it being to make in order to the below method:
(a) get Radix Polygoni Multiflori 8% by weight, Lentinus Edodes 8%, Tremella 5.8%, Poria 6%, Radix Notoginseng 8% and Radix Codonopsis 8% pulverized, after the drinking water that added 1: 1 is mixed thoroughly, with in every bottle of 0.07 kilogram of wide mouthed bottle of packing into as Chinese medicine medicine base, place sterilizing pan then, with 121 ℃ of high-temperature sterilization sterilizations 2 hours, move to after the cooling in the aseptic inoculation chamber, (CGMCC0132) strain of edible meat fungus with the said Basidiomycetes of ZL88100118.X patent (Basidiomycetes) Aphyllophorales (Aphyllophorales) hedgehog hydnum Cordycepps (Hericiaceae) Hericium (Hericium) inserts in the above-mentioned Chinese medicine medicine base, placing temperature is 22~27 ℃, humidity is 65~70% biological engineering cultivation workshop, cultivate after 20~25 days, taking-up is covered with the medicine base of hericium mycelium, be cut into fragment, place vacuum desiccator, after the drying, it is standby to be ground into medicated powder in ultrafine crusher in 70 ℃ low temperature;
(b) get Radix Salviae Miltiorrhizae 17%, Rhizoma Chuanxiong 12%, Radix Angelicae Sinensis 8%, Fructus Crataegi 9% and Radix Glycyrrhizae 5% washing back merging according to weight ratio again and put into the Chinese medicine extraction jar, the pure water that adds 5 times of raw material weights, decoct 2 hours, pour out medicinal liquid, the pure water that adds 2.5 times of raw material weights more respectively for twice, pour out medicinal liquid after respectively decocting 1 hour, the medicinal liquid of pouring out for three times merged to filter be placed in the medicinal liquid concentration pan, obtaining at 1: 1 in temperature by the dried medicine weight of raw material is that 60~80 ℃, heat survey proportion are 1: 1.18 o'clock water extracting liquid;
(c) medicated powder that (a) obtained; after adding is poured into and is stirred in the blender by weight the calcium carbonate 5% that takes out, magnesium stearate 0.2% merging; pour the water extracting liquid that (b) obtains again into; place automatic mixer-granulator to make granule; being dried to moisture content in 70 ℃ of low temperature is ± 5%, places automatic tableting press to make plain sheet then.
2,, it is characterized in that also comprising in the wherein said method that the plain sheet that will be pressed into places the film coating machine to carry out coating according to the tablet of the said a kind of blood pressure lowering and heart protecting of claim 1.
CN 00117531 2000-10-25 2000-10-25 Blood pressure lowering and heart protecting tablet and its production process Expired - Fee Related CN1211095C (en)

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Application Number Priority Date Filing Date Title
CN 00117531 CN1211095C (en) 2000-10-25 2000-10-25 Blood pressure lowering and heart protecting tablet and its production process

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Application Number Priority Date Filing Date Title
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CN1211095C true CN1211095C (en) 2005-07-20

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1296062C (en) * 2004-03-04 2007-01-24 叶美曾 Codonopsis effective component and preparaation method of its medicinal preparation of codenopsis rich paste
CN101194947B (en) * 2007-11-03 2010-06-09 彭华中 Chinese medicine for treating angiocardiopathy
CN103316163A (en) * 2013-05-20 2013-09-25 缪长法 Traditional Chinese medicine used for treating coronary heart disease, and preparation method thereof
CN106923314A (en) * 2017-01-22 2017-07-07 广东福寿仙生物科技有限公司 A kind of health composition containing selenium and its application

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