CN117679339A - Anti-aging composition and preparation method and application thereof - Google Patents
Anti-aging composition and preparation method and application thereof Download PDFInfo
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- CN117679339A CN117679339A CN202311472160.1A CN202311472160A CN117679339A CN 117679339 A CN117679339 A CN 117679339A CN 202311472160 A CN202311472160 A CN 202311472160A CN 117679339 A CN117679339 A CN 117679339A
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- Cosmetics (AREA)
Abstract
The invention belongs to the technical field of cosmetics, and discloses an anti-aging composition, a preparation method and application thereof. The anti-aging composition of the invention comprises the following components: oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthes extract. The anti-aging composition is prepared by reasonably compounding oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthum extract, the components exert a synergistic effect, and the product is mild, not stimulated, not greasy, easy to be absorbed by skin, has the effects of resisting oxidation, tightening and resisting wrinkles, and can achieve the effective anti-aging effect.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to an anti-aging composition, and a preparation method and application thereof.
Background
With age, skin can develop aging phenomena including fine lines, sagging skin, etc., due to the reduction of collagen and elastin in the skin, and damage to the skin by free radicals. The phenomenon of skin aging is more and more obvious, and how to effectively resist the aging is the research focus in the field of skin care. At present, the existing anti-aging products in the market mainly aim at repairing existing deep wrinkles, most of the products only adopt a single component to achieve the effect of short-term wrinkle reduction, and skin care products aiming at the improvement of the comprehensive state of skin are relatively few or poor in use effect, or the skin feel is greasy due to the addition of excessive components, even the irritation is large, so that the anti-aging effect is limited to a certain extent.
Therefore, it is highly desirable to develop a product that is mild, non-irritating, non-greasy, and effective against the elderly.
Disclosure of Invention
The present invention aims to solve at least one of the technical problems in the prior art described above. Therefore, the invention provides an anti-aging composition, a preparation method and application thereof, and the anti-aging composition is mild, non-irritating, non-greasy, and has the effects of resisting oxidation, tightening and resisting wrinkle, thereby achieving the effect of effectively resisting aging.
In a first aspect the present invention provides an anti-presbyopia composition comprising the following components: oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthes extract.
Specifically, the efficacy of each component in the anti-aging composition of the invention is as follows:
the grape seed oil contains linoleic acid, which can maintain the skin barrier and channel functions, is easy to be absorbed by skin, can deeply nourish and condition skin cells, has the function of scavenging free radicals, can promote the moderate crosslinking of collagen, and can prevent wrinkles and vesicles from occurring on skin. In addition, the mass fraction of VE in grape seed oil is about 360.20 mug/g, and VE can accelerate the removal of damaged cells and senescent cells and has the function of delaying senescence. Grape seed oil is rich in vitamins, minerals and flavanols (procyanidins) and helps to strengthen collagen and elastin, which make up connective tissue of the skin and joints. Omega-6 linoleic acid content in grapeseed oil is particularly high (about 76%), so the texture is fresh and easy to penetrate into deep skin. The grape seed extract has the function of conditioning, and simultaneously has the effect of astringing, so that the grape seed extract can condition skin. Grape seed oil is directly coated on skin and is easily absorbed by skin. The grape seed oil can also accelerate metabolism of skin, quicken the updating speed of skin, protect skin epidermal cells and new cells, protect skin moisture and has a certain moisturizing effect.
The camellia seed oil is rich in unit unsaturated oleic acid (about 80%), and the camellia seed oil does not block pores and is not greasy because of the tannin component. The camellia seed oil belongs to astringent vegetable oil, and is more suitable for treating oily or problematic skin than other oil products rich in oleic acid. The camellia seed oil is dry and cold in nature and can prevent skin aging. The camellia seed oil has the effects of moisturizing and moisturizing skin; in addition, the plant polyphenol, vitamin A, B, C, E and other antioxidants are protected from ultraviolet rays, environment and free radicals. The camellia seed oil is also easily absorbed by skin, and the plant squalene component contained in the camellia seed oil can nourish and maintain skin health.
About 20% of avocado oil is unsaturated linoleic acid, about 12% is rare palmitoleic acid, which nourishes the skin and maintains the health of the stratum corneum, wherein the avocado oil is also rich in vitamin A, B, E, protein and amino acids, and trace amounts of lecithin, and the avocado oil promotes collagen proliferation of dermis (middle layer of skin), and the plant sterol component thereof maintains collagen and skin structure, prevents senile plaques and cell wall weakening, simultaneously relieves inflammation symptoms, promotes tissue regeneration, and maintains the barrier function of the skin. Avocado oil is a few carotenoid-rich vegetable oils that are naturally protected from the hazards of ultraviolet light.
The oat kernel oil has a balance of oleic acid and linoleic acid, about 40% each, which is particularly beneficial to the stratum corneum of the skin. Palmitic acid is a fatty acid with a shorter carbon chain, which can sooth and protect the outer skin. Oat kernel oil is also rich in vitamin E, antioxidants and carotenoids. Oat kernel oil contains more than 20 unique polyphenol components and can resist inflammation, hyperplasia and itching. Notably, anthranilamide (Avenanthramide), a powerful antioxidant, can protect against fungal attack. The beta-glucan (beta-glucan) component of oat kernel oil is rich in polysaccharides, soluble fiber and phospholipids.
The spilanthol extract is rich in alkylamides and is considered a natural alternative to botulinum toxin; the dermal structure can be improved by stimulating the activity of fibroblasts to tighten skin, and the skin care composition can treat dermatitis, enhance the resistance of capillaries, eliminate free radical oxidation resistance and relieve aging, and has a certain inhibition effect on melanocytes. The spilanthum flower extract has the effects of improving dermis structure, tightening skin, treating dermatitis, enhancing capillary resistance, eliminating free radical, resisting oxidation, and relieving aging.
The composition obtained by compounding a plurality of specific vegetable oils and extracts can supplement lipids secreted by the skin and supplement the lipids lacking in the skin, and meanwhile, the vegetable oils contain antioxidants, so that the health function of skin cells is maintained by natural and nutritional sun-screening substances; the components in the composition have synergistic effect, promote the moderate crosslinking of collagen from multiple angles and all directions, prevent skin from wrinkling and vesicular, accelerate the removal of damaged cells and aging cells, and have the effects of resisting oxidation, tightening and resisting wrinkle, thereby achieving the purpose of effectively resisting the primary aging.
According to some embodiments of the invention, the anti-aging composition comprises the following components: 1-20 parts of oat kernel oil, 1-50 parts of grape seed oil, 1-50 parts of avocado oil, 1-50 parts of camellia seed oil and 0.01-2 parts of spilanthes extract.
According to some embodiments of the invention, the anti-aging composition comprises the following components in parts by weight: 5-20 parts of oat kernel oil, 5-50 parts of grape seed oil, 5-50 parts of avocado oil, 5-50 parts of camellia seed oil and 0.5-2 parts of spilanthes extract.
According to some embodiments of the invention, the anti-aging composition comprises the following components in parts by weight: 5-15 parts of oat kernel oil, 5-35 parts of grape seed oil, 5-35 parts of avocado oil, 5-45 parts of camellia seed oil and 0.5-1.5 parts of spilanthes extract.
The second aspect of the invention provides a method for preparing the anti-aging composition of the invention, comprising the steps of:
mixing the oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthum extract to obtain the anti-aging composition.
In a third aspect, the invention provides a cosmetic comprising an anti-aging composition according to the invention.
According to some embodiments of the invention, the composition is added to the cosmetic in an amount of 5-50wt%.
According to some embodiments of the invention, the composition is added to the cosmetic in an amount of 10-30wt%.
According to some embodiments of the invention, the cosmetic formulation is selected from a cream, lotion, aqua, gel or facial mask patch.
In a fourth aspect, the invention provides an essential oil comprising an anti-aging composition according to the invention.
Compared with the prior art, the invention has the following beneficial effects:
according to the invention, oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthum flower extract are reasonably compounded, a synergistic effect is exerted among the components, and the product is mild, not stimulated, not greasy, easy to be absorbed by skin, has the effects of resisting oxidation, tightening and resisting wrinkles, and can achieve the effect of effectively resisting the initial aging.
Detailed Description
The present invention will be described in further detail with reference to specific examples. The starting materials, reagents or apparatus used in the examples are all commercially available from conventional sources or may be obtained by methods known in the art unless otherwise specified. Unless otherwise indicated, assays or testing methods are routine in the art.
Example 1
An anti-aging composition comprises the following components in parts by mass:
9 parts of oat kernel oil, 25 parts of grape seed oil, 25 parts of avocado oil, 40 parts of camellia seed oil and 1 part of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 2
An anti-aging composition comprises the following components in parts by mass:
12 parts of oat kernel oil, 29 parts of grape seed oil, 29 parts of avocado oil, 29 parts of camellia seed oil and 1 part of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 3
An anti-aging composition comprises the following components in parts by mass:
15 parts of oat kernel oil, 35 parts of grape seed oil, 30 parts of avocado oil, 19.2 parts of camellia seed oil and 0.8 part of spilanthes extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 4
An anti-aging composition comprises the following components in parts by mass:
13 parts of oat kernel oil, 22 parts of grape seed oil, 35 parts of avocado oil, 28.8 parts of camellia seed oil and 1.2 parts of spilanthes extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 5
An anti-aging composition comprises the following components in parts by mass:
10 parts of oat kernel oil, 30 parts of grape seed oil, 43.5 parts of avocado oil, 15 parts of camellia seed oil and 1.5 parts of spilanthes extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 6
An anti-aging composition comprises the following components in parts by mass:
1 part of oat kernel oil, 1 part of grape seed oil, 50 parts of avocado oil, 47 parts of camellia seed oil and 1 part of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 7
An anti-aging composition comprises the following components in parts by mass:
1 part of oat kernel oil, 50 parts of grape seed oil, 1 part of avocado oil, 47 parts of camellia seed oil and 1 part of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 8
An anti-aging composition comprises the following components in parts by mass:
20 parts of oat kernel oil, 50 parts of grape seed oil, 28 parts of avocado oil, 1 part of camellia seed oil and 1 part of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 9
An anti-aging composition comprises the following components in parts by mass:
1 part of oat kernel oil, 46 parts of grape seed oil, 50 parts of avocado oil, 1 part of camellia seed oil and 2 parts of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 10
An anti-aging composition comprises the following components in parts by mass:
18 parts of oat kernel oil, 34 parts of grape seed oil, 45 parts of avocado oil, 1 part of camellia seed oil and 2 parts of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Example 11
An anti-aging composition comprises the following components in parts by mass:
20 parts of oat kernel oil, 1 part of grape seed oil, 27 parts of avocado oil, 50 parts of camellia seed oil and 2 parts of spilanthol extract. The anti-aging composition is prepared by mixing the components according to the formula amount.
Comparative examples 1 to 5
Comparative examples 1 to 5 each contained only one component, as shown in Table 1.
TABLE 1
| Comparative example 1 | Comparative example 2 | Comparative example 3 | Comparative example 4 | Comparative example 5 |
| Oat kernel oil 100 parts | Grape seed oil 100 parts | Avocado oil 100 parts | 100 parts of camellia seed oil | 100 parts of spilanthol extract |
Comparative examples 6 to 10 each lack one component, specifically as follows:
comparative example 6
An anti-aging composition comprises the following components in parts by mass:
27.4 parts of grape seed oil, 27.4 parts of avocado oil, 43.8 parts of camellia seed oil and 1.4 parts of spilanthol extract.
The anti-aging composition is prepared by mixing the components according to the formula amount.
Comparative example 7
An anti-aging composition comprises the following components in parts by mass:
11.9 parts of oat kernel oil, 33.4 parts of avocado oil, 53.4 parts of camellia seed oil and 1.3 parts of spilanthol extract.
The anti-aging composition is prepared by mixing the components according to the formula amount.
Comparative example 8
An anti-aging composition comprises the following components in parts by mass:
11.9 parts of oat kernel oil, 33.4 parts of grape seed oil, 53.4 parts of camellia seed oil and 1.3 parts of spilanthol extract.
The anti-aging composition is prepared by mixing the components according to the formula amount.
Comparative example 9
An anti-aging composition comprises the following components in parts by mass:
15 parts of oat kernel oil, 41.67 parts of grape seed oil, 41.67 parts of avocado oil and 1.66 parts of spilanthum flower extract.
The anti-aging composition is prepared by mixing the components according to the formula amount.
Comparative example 10
An anti-aging composition comprises the following components in parts by mass:
9.1 parts of oat kernel oil, 25.25 parts of grape seed oil, 25.25 parts of avocado oil and 40.4 parts of camellia seed oil.
The anti-aging composition is prepared by mixing the components according to the formula amount.
Comparative example 11
Comparative example 11 differs from example 1 in that comparative example 11 replaces grape seed oil with olive fruit oil, and other components, addition amounts, and preparation methods are the same as example 1.
Comparative example 12
Comparative example 12 differs from example 1 in that comparative example 12 replaces camellia seed oil with white pond flower seed oil, and other components, addition amounts, and preparation methods are the same as example 1.
Comparative example 13
Comparative example 13 differs from example 1 in that comparative example 13 replaces oat kernel oil with wheat germ oil, and other components, addition amounts, and preparation methods are the same as example 1.
Comparative example 14
Comparative example 14 differs from example 1 in that comparative example 14 replaces avocado oil with chicory seed oil, and other components, addition amounts, and preparation methods are the same as example 1.
Comparative example 15
Comparative example 15 differs from example 1 in that comparative example 15 replaces the spilanthus altissima extract with rose hip oil, and other components, addition amounts, and preparation methods are the same as example 1.
Application example 1
An essential oil comprising the anti-aging composition of the present invention is formulated as shown in table 2.
TABLE 2
The essential oil is prepared by mixing the components of the group A, the group B, the group C and the group D according to the proportion of the table 2 at room temperature and uniformly stirring.
Application example 2
The difference from application example 1 is that the anti-ageing composition of example 1 has a mass percentage of 5% and the isononyl isononanoate mass percentage should be correspondingly increased, but still added to 100%, the percentage content of the remaining components being unchanged.
Application example 3
The difference from application example 1 is that the anti-ageing composition of example 1 has a mass percentage of 50% and the isononyl isononanoate mass percentage should be correspondingly reduced but still added to 100% with the percentages of the remaining components unchanged.
Application example 4
The difference from application example 1 is that the anti-ageing composition of example 1 has a mass percentage of 4% and the isononyl isononanoate mass percentage should be correspondingly increased, but still added to 100%, the percentage content of the remaining components being unchanged.
Application example 5
The difference from application example 1 is that the anti-ageing composition of example 1 has a mass percentage of 55% and the isononyl isononanoate mass percentage should be correspondingly reduced but still added to 100% with the percentages of the remaining components unchanged.
Application example 6
Application example 6 differs from application example 1 in that application example 6 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 2, and other components, addition amounts, and production methods are the same as application example 1.
Application example 7
Application example 7 differs from application example 1 in that application example 7 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 3, and other components, addition amounts, and production methods are the same as application example 1.
Application example 8
Application example 8 differs from application example 1 in that application example 8 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 4, and other components, addition amounts, and production methods are the same as application example 1.
Application example 9
Application example 9 differs from application example 1 in that application example 9 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 5, and other components, addition amounts, and production methods are the same as application example 1.
Application example 10
Application example 10 differs from application example 1 in that application example 10 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 6, and other components, addition amounts, and production methods are the same as application example 1.
Application example 11
Application example 11 differs from application example 1 in that application example 11 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 7, and other components, addition amounts, and production methods are the same as application example 1.
Application example 12
Application example 12 differs from application example 1 in that application example 12 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 8, and other components, addition amounts, and production methods are the same as application example 1.
Application example 13
Application example 13 differs from application example 1 in that application example 13 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 9, and other components, addition amounts, and production methods are the same as application example 1.
Application example 14
Application example 14 differs from application example 1 in that application example 14 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 10, and other components, addition amounts, and production methods are the same as application example 1.
Application example 15
Application example 15 differs from application example 1 in that application example 15 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of example 11, and other components, addition amounts, and production methods are the same as application example 1.
Comparative example 1 was used
The difference from application example 1 is that, without the addition of the anti-ageing composition of example 1, the mass percentage of isononyl isononanoate should be correspondingly increased, but still to 100%, the percentage of the remaining components being unchanged
Comparative example 2 was used
Application comparative example 2 differs from application example 1 in that application comparative example 2 replaces the anti-presenility composition of example 1 with the anti-presenility composition of comparative example 1, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 3 was used
Application comparative example 3 differs from application example 1 in that application comparative example 3 replaces the anti-presenility composition of example 1 with the anti-presenility composition of comparative example 2, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 4 was used
Application comparative example 4 differs from application example 1 in that application comparative example 4 replaces the anti-presenility composition of example 1 with that of comparative example 3, and other components, addition amounts, and preparation methods are the same as application example 1.
Comparative example 5 was used
Application comparative example 5 differs from application example 1 in that application comparative example 5 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 4, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 6 was used
Application comparative example 6 differs from application example 1 in that application comparative example 6 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 5, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 7 was used
Application comparative example 7 differs from application example 1 in that application comparative example 7 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 6, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 8 was used
Application comparative example 8 differs from application example 1 in that application comparative example 8 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 7, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 9 was used
Application comparative example 9 differs from application example 1 in that application comparative example 9 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 8, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 10 was used
Application comparative example 10 differs from application example 1 in that application comparative example 10 replaces the anti-presenility composition of example 1 with the anti-presenility composition of comparative example 9, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 11 was used
Application comparative example 11 differs from application example 1 in that application comparative example 11 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 10, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 12 was used
Application comparative example 12 differs from application example 1 in that application comparative example 12 replaces the anti-presenility composition of example 1 with the anti-presenility composition of comparative example 11, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 13
Application comparative example 13 differs from application example 1 in that application comparative example 13 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 12, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 14 was used
Application comparative example 14 differs from application example 1 in that application comparative example 14 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 13, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 15 was used
Application comparative example 15 differs from application example 1 in that application comparative example 15 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 14, and other components, addition amounts, and production method are the same as application example 1.
Comparative example 16 was used
Application comparative example 16 differs from application example 1 in that application comparative example 16 replaces the anti-preseniling composition of example 1 with the anti-preseniling composition of comparative example 15, and other components, addition amounts, and production method are the same as application example 1.
Test example 1 Patch test
Test article: essential oils of application examples 1 to 15 and application comparative examples 1 to 16.
The subject: a total of 50, 25 men and 25 women, aged 20-40, met the inclusion criteria of the tested volunteers.
The test method comprises the following steps: a sample of 0.03mL was taken with a syringe and placed in the drug chamber of the plaque test tape, and the plaque test tape with the sample placed therein was immediately applied to the normal skin of the left forearm longitudinally from the lower part while gently pressing the drug chamber one by one to expel air and uniformly distribute the test substance. The test sites were marked for observation. The blank group was subjects without product.
Analysis of results: the plaque tape was removed after 24 hours, skin reactions were observed after 30 minutes, 24 hours and 48 hours, respectively, and the results of the skin reactions were recorded according to CTFA guidelines for analysis. The adverse reaction grade of the skin is shown in Table 3, and the test results are shown in Table 4.
TABLE 3 Table 3
| Grade | (symbol) | Authentication criteria |
| 0 | - | Negative reaction: no irritation and erythema |
| 1 | ± | Suspicious reaction: mild erythema |
| 2 | + | Weak positive reaction: erythema (red spot) |
| 3 | ++ | Strong positive reaction: erythema, papule and blister |
| 4 | +++ | Very strong positive reaction: severe edema, large foam |
TABLE 4 Table 4
As can be seen from the data of table 4, among 50 subjects, the essential oils prepared using application examples 1 to 15, application comparative example 1, application comparative example 2, application comparative example 3, application comparative example 4, application comparative example 5, application comparative example 7, application comparative example 8, application comparative example 9, application comparative example 11, application comparative example 12, application comparative example 13, application comparative example 14, application comparative example 15, application comparative example 16 did not show skin adverse reaction; the essential oils prepared by using the application comparative example 6 and the application comparative example 10 respectively have 1-example 1-grade adverse reaction, which shows that the essential oil added with the anti-aging composition of the invention is milder, safer and has no stimulation.
Test example 2 determination of superoxide anion radical scavenging Capacity
And (3) testing a sample: anti-aging compositions of examples 1-11 and comparative examples 1-15.
The specific measurement method is as follows:
4.5mL of Tris-HCl buffer with the pH of 0.05mol/L and 8.2 is taken and preheated in a water bath kettle at 25 ℃ for 20min. Then 1mL of the sample to be tested is added, then 0.4mL of 25mmol/L pyrogallol solution which is preheated for 20min in a water bath at 25 ℃ is added, after being uniformly mixed, the mixture is reacted for 5min in the water bath at 25 ℃, and 1.0mL of 8mol/L hydrochloric acid is added to stop the reaction. The absorbance was measured at 299nm using Tris-HCl buffer as reference.
Blank control experiment: the test sample was replaced with only 1mL of ethanol, and the other steps were unchanged. The clearance (D) is calculated according to equation (1).
D (%) = [1- (A2/A1) ] ×100% formula (1);
1) Wherein A1 is the absorbance value of the blank; a2 is the absorbance value of the sample to be tested after the test.
The test results are shown in Table 5.
TABLE 5
As can be seen from Table 5, the anti-aging compositions of examples 1 to 11 all had better radical scavenging ability, but the effects of examples 1 to 11 were not achieved by using only a single component (comparative examples 1 to 5), or a composition lacking any one of the components (comparative examples 6 to 10), or by replacing the components of example 1 with other components having similar effects (comparative examples 11 to 15).
Test example 3 tightening human efficacy test
Test article: essential oils of application examples 1 to 15 and application comparative examples 1 to 16.
The experimental method comprises the following steps: 310 groups of subjects with wrinkles on their periocular skin (30-45 years old) were selected as compactly anti-wrinkle efficacy test volunteers (the same sample was used for every 10 volunteers). The subjects used the product once a day earlier than the eyes, before using (D0), on the 7 th day (D7) and on the 14 th day (D14), after waiting 20min for the cleaning face of the subjects under the conditions of the temperature of 21+/-1 ℃ and the humidity of 50+/-10%, the face elasticity-R2 value is measured, and the tightening effect of the product on the skin of the human body is comprehensively evaluated.
Test instrument: skin elasticity tester MPA580 (manufactured by CK company, germany).
By measuring skin elasticity-R2 value, rate of change of elasticity (R2 value): refers to the rate of change of skin elasticity after application of the product versus before application. A positive value indicates an increase in the ratio of the maximum tensile displacement of the skin, and a negative value indicates a decrease in the ratio of the maximum tensile displacement of the skin, the worse the skin elasticity; to evaluate the tightening efficacy of the product.
And (3) result judgment: the result of the change of the instrument test parameter (elasticity R2 value) is improved after the product is used and any visit point is compared with that before the product is used, the product is considered to have the tightening effect, otherwise, the product is considered to not have the tightening effect. The test results are shown in Table 6.
TABLE 6
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As can be seen from table 6, the essential oils of application examples 1 to 15 all have a tightening effect, but the content of the anti-aging composition of application example 4 is too low (less than 5%), and the effect is reduced; the anti-aging composition in application example 5 has too high content (more than 50%), the R2 change rate is lower, the cosmetic is easy to be too greasy, the use feel is poor, the nutrition ingredients are difficult to absorb, pores can be blocked, and the effect of the cosmetic is affected; the effect of application examples 1 to 15 could not be achieved by using only a single component (application comparative examples 2 to 6), or a composition lacking any one of the components (application comparative examples 7 to 11), or by replacing the components in the anti-aging composition of the present invention with other components having similar effects (application comparative examples 12 to 16).
Test example 4 anti-wrinkle human efficacy test
Test article: essential oils of application examples 1 to 15 and application comparative examples 1 to 16.
The testing method comprises the following steps: the population (30-45 years old) 310 of subjects with wrinkles on the skin around eyes was selected as a tightening anti-wrinkle efficacy test volunteer (the same sample was used for every 10 volunteers)) (same as the volunteer in test example 3), and the subjects used once a day each time after the eyes, and after the time of use (D0), 7 th day (D7) and 14 th day (D14), the subjects were subjected to face photographing with VISIA 7 after waiting for 20 minutes at a temperature of 21±1 ℃ and a humidity of 50±10%, and the number of wrinkles around the eyes (bar number), the total area number of wrinkles, the average length number of wrinkles, and the area ratio number of wrinkles were measured to evaluate the anti-wrinkle efficacy of the products.
Average length value change rate of wrinkles: refers to the average length of wrinkles around the eyes after application of the product versus the rate of change before application. Positive values indicate an increase in the average length of periocular wrinkles, the longer the average length of periocular wrinkles; negative values indicate a decrease in the average length of periocular wrinkles, the shorter the average length of periocular wrinkles.
Wrinkle number (bar) value change rate: refers to the number of wrinkles around the eyes (bars) after use of the product versus the rate of change before use. Positive values indicate an increase in the number of periocular wrinkles, the more periocular wrinkles; negative values indicate a decrease in the number of periocular wrinkles, the fewer periocular wrinkles.
Total area value change rate of wrinkles: refers to the total area of periocular wrinkles after use of the product versus the rate of change before use. Positive values indicate that the total area of periocular wrinkles increases, the more periocular wrinkles are; negative values indicate that the total area of periocular wrinkles is reduced and that periocular wrinkles are reduced.
Wrinkle area ratio change rate: refers to the ratio of the area of wrinkles around the eyes after use of the product versus the rate of change before use. Positive values indicate an increase in the area ratio of periocular wrinkles, the more periocular wrinkles; negative values indicate a decrease in the area of periocular wrinkles, the fewer periocular wrinkles.
The test results are shown in Table 7.
TABLE 7
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As is clear from Table 7, the essential oils of application examples 1 to 15 all have anti-wrinkle ability, but the content of the anti-aging composition of application example 4 is too low (less than 5%), and the effect is reduced; although the amount of the anti-aging composition in application example 5 was too high (more than 50%), the number of facial periocular wrinkles (bars), the total area of wrinkles, the average length of wrinkles, and the area of wrinkles were all reduced in the first 7 days, but the number of facial periocular wrinkles (bars), the total area of wrinkles, the average length of wrinkles, and the area of wrinkles were increased in the first 14 days, which was contrary to the 7 days, and the corresponding effects were not achieved, and the cosmetic was easily too greasy, the feeling of use was poor, the nutrient components were difficult to absorb, and pores were blocked, and the effect of the cosmetic was affected; the effect of application examples 1 to 15 could not be achieved by using only a single component (application comparative examples 2 to 6), or a composition lacking any one of the components (application comparative examples 7 to 11), or by replacing the components in the anti-aging composition of the present invention with other components having similar effects (application comparative examples 12 to 16).
According to the experimental results, the quality percentage of the anti-aging composition in the cosmetics is regulated and controlled by regulating and controlling the proportion of each component in the anti-aging composition, so that a more excellent anti-aging effect can be obtained.
While the preferred embodiments of the present invention have been illustrated and described, the present invention is not limited to the embodiments, and various equivalent modifications and substitutions can be made by one skilled in the art without departing from the spirit of the present invention, and these are intended to be included in the scope of the present invention as defined in the appended claims.
Claims (10)
1. An anti-aging composition, characterized in that the anti-aging composition comprises the following components: oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthes extract.
2. The anti-presenility composition according to claim 1, characterized in that it comprises, in parts by mass: 1-20 parts of oat kernel oil, 1-50 parts of grape seed oil, 1-50 parts of avocado oil, 1-50 parts of camellia seed oil and 0.01-2 parts of spilanthes extract.
3. The anti-presenility composition according to claim 2, characterized in that it comprises, in parts by mass: 5-20 parts of oat kernel oil, 5-50 parts of grape seed oil, 5-50 parts of avocado oil, 5-50 parts of camellia seed oil and 0.5-2 parts of spilanthes extract.
4. An anti-presenility composition according to claim 3, characterized in that it comprises, in parts by mass: 5-15 parts of oat kernel oil, 5-35 parts of grape seed oil, 5-35 parts of avocado oil, 5-45 parts of camellia seed oil and 0.5-1.5 parts of spilanthes extract.
5. A process for the preparation of an anti-aging composition according to any one of claims 1 to 4, comprising the steps of:
mixing the oat kernel oil, grape seed oil, avocado oil, camellia seed oil and spilanthum extract to obtain the anti-aging composition.
6. A cosmetic comprising the anti-aging composition according to any one of claims 1 to 4.
7. The cosmetic product according to claim 6, wherein the anti-aging composition is added in an amount of 5 to 50wt%.
8. The cosmetic product according to claim 7, wherein the anti-aging composition is added in an amount of 10 to 30wt%.
9. The cosmetic product according to claim 6, wherein the cosmetic product is in a form selected from the group consisting of cream, lotion, aqua, gel and facial mask.
10. An essential oil comprising the anti-aging composition of any one of claims 1 to 4.
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