CN117442530A - Calendula emulsion capable of diminishing inflammation and relieving allergy - Google Patents
Calendula emulsion capable of diminishing inflammation and relieving allergy Download PDFInfo
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- CN117442530A CN117442530A CN202311556173.7A CN202311556173A CN117442530A CN 117442530 A CN117442530 A CN 117442530A CN 202311556173 A CN202311556173 A CN 202311556173A CN 117442530 A CN117442530 A CN 117442530A
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- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 title claims abstract description 51
- 235000003880 Calendula Nutrition 0.000 title claims abstract description 51
- 239000000839 emulsion Substances 0.000 title claims abstract description 41
- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract description 27
- 208000026935 allergic disease Diseases 0.000 title claims abstract description 27
- 241000132025 Calendula Species 0.000 title claims description 49
- 206010061218 Inflammation Diseases 0.000 title claims description 25
- 230000004054 inflammatory process Effects 0.000 title claims description 25
- 230000003467 diminishing effect Effects 0.000 title claims description 23
- 230000007815 allergy Effects 0.000 title claims description 20
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 48
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 43
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 31
- 239000008169 grapeseed oil Substances 0.000 claims abstract description 22
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 21
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 21
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 21
- 241000208680 Hamamelis mollis Species 0.000 claims abstract description 16
- 239000004166 Lanolin Substances 0.000 claims abstract description 16
- 239000008367 deionised water Substances 0.000 claims abstract description 16
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 16
- 229940039717 lanolin Drugs 0.000 claims abstract description 16
- 235000019388 lanolin Nutrition 0.000 claims abstract description 16
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229940032094 squalane Drugs 0.000 claims abstract description 16
- 229940067866 dandelion extract Drugs 0.000 claims abstract description 13
- 235000020691 dandelion extract Nutrition 0.000 claims abstract description 13
- 239000001845 taraxacum officinale leaf extract Substances 0.000 claims abstract description 13
- 229940119217 chamomile extract Drugs 0.000 claims abstract description 12
- 235000020221 chamomile extract Nutrition 0.000 claims abstract description 12
- 229940118846 witch hazel Drugs 0.000 claims abstract description 11
- 230000003110 anti-inflammatory effect Effects 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims description 40
- 150000002894 organic compounds Chemical class 0.000 claims description 33
- 239000011259 mixed solution Substances 0.000 claims description 30
- 239000003795 chemical substances by application Substances 0.000 claims description 26
- 230000003750 conditioning effect Effects 0.000 claims description 26
- 239000002994 raw material Substances 0.000 claims description 26
- 239000003921 oil Substances 0.000 claims description 16
- 235000011187 glycerol Nutrition 0.000 claims description 15
- 235000019198 oils Nutrition 0.000 claims description 15
- 239000003906 humectant Substances 0.000 claims description 14
- 239000004519 grease Substances 0.000 claims description 12
- 238000006243 chemical reaction Methods 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 10
- 238000007599 discharging Methods 0.000 claims description 8
- 229940087559 grape seed Drugs 0.000 claims description 6
- 238000005406 washing Methods 0.000 claims description 6
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 claims description 5
- 239000004215 Carbon black (E152) Substances 0.000 claims description 5
- AEMOLEFTQBMNLQ-AQKNRBDQSA-N D-glucopyranuronic acid Chemical compound OC1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-AQKNRBDQSA-N 0.000 claims description 5
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims description 5
- 244000042664 Matricaria chamomilla Species 0.000 claims description 5
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims description 5
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 claims description 5
- 230000001804 emulsifying effect Effects 0.000 claims description 5
- 229940097043 glucuronic acid Drugs 0.000 claims description 5
- 229930195733 hydrocarbon Natural products 0.000 claims description 5
- 150000002430 hydrocarbons Chemical class 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 239000000243 solution Substances 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- 229940031439 squalene Drugs 0.000 claims description 5
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 claims description 5
- 229920001059 synthetic polymer Polymers 0.000 claims description 5
- 229940073728 taraxacum mongolicum extract Drugs 0.000 claims description 5
- 239000002562 thickening agent Substances 0.000 claims description 5
- 239000001993 wax Substances 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims description 5
- 229910010272 inorganic material Inorganic materials 0.000 claims description 4
- 239000011147 inorganic material Substances 0.000 claims description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 239000003513 alkali Substances 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 229940125782 compound 2 Drugs 0.000 claims description 3
- 239000010779 crude oil Substances 0.000 claims description 3
- 239000012153 distilled water Substances 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 235000021588 free fatty acids Nutrition 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 230000007935 neutral effect Effects 0.000 claims description 3
- 238000007670 refining Methods 0.000 claims description 3
- 239000000341 volatile oil Substances 0.000 claims description 3
- 239000002351 wastewater Substances 0.000 claims description 3
- 239000005416 organic matter Substances 0.000 claims description 2
- 229940125898 compound 5 Drugs 0.000 claims 1
- 230000003266 anti-allergic effect Effects 0.000 abstract description 2
- 240000001432 Calendula officinalis Species 0.000 abstract 2
- 230000003020 moisturizing effect Effects 0.000 description 5
- 206010070834 Sensitisation Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002040 relaxant effect Effects 0.000 description 3
- 230000008313 sensitization Effects 0.000 description 3
- 206010013786 Dry skin Diseases 0.000 description 2
- 230000037336 dry skin Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010046865 Vaccinia virus infection Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
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Abstract
The invention discloses an anti-inflammatory and allergy-relieving calendula emulsion which comprises 68.55% -79.67% of deionized water, 2.5% -10.9% of glycerol, 0.5% -2.7% of dandelion extract, 0.4% -3.2% of calendula extract, 1.5% -4.1% of witch hazel extract, 2.3% -5.3% of chamomile extract, 2% -8% of propylene glycol, 0.7% -2.1% of lanolin, 0.03% -0.13% of sodium hyaluronate, 0.42% -0.90% of squalane, 0.6% -1.9% of grape seed oil and 0.5% -1.1% of hydrogenated polydecene.
Description
Technical Field
The invention relates to calendula emulsion capable of diminishing inflammation and relieving allergy, and belongs to the technical field of cosmetics.
Background
The emulsion is a moisturizing skin care product, is generally an oil-in-water emulsion system, has higher grease components, can prevent skin moisture from losing too fast, can prevent skin from cracking and peeling, has good moisturizing and moisturizing effects, and has the greatest characteristics that the emulsion is very high in water content, can moisten skin instantly and can supplement moisture for dry skin. The emulsion can form a light, thin and breathable protective film on the surface of the skin, can prevent water loss, and has an excellent moisturizing effect. Therefore, the emulsion is more suitable for use in dry seasons than simple moisturizing lotion. In addition, the grease in the emulsion has better moistening degree than the moisture. Therefore, the emulsion is a good choice no matter whether the skin is dry skin without water or oil.
When a part of users use the calendula emulsion, the skin surface is exposed to the outside of air, so that impurities are easy to adhere to the skin surface, and inflammation occurs on the skin surface, so that the calendula emulsion capable of diminishing inflammation and relieving allergy is needed.
Disclosure of Invention
The invention aims to provide calendula emulsion capable of diminishing inflammation and relieving allergy, so as to solve the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions: an anti-inflammatory and allergy-relieving calendula emulsion comprises the following raw materials in parts by weight:
as a preferable technical scheme of the invention, the calendula emulsion capable of diminishing inflammation and relaxing sensitization is prepared from the following raw materials in parts by weight:
raw material name | Variety of raw materials | Dosage of | Purpose of use |
Deionized water | Inorganic material | 68.55% | Solvent(s) |
Glycerol | Organic compound | 2.5% | Humectant type |
Taraxacum mongolicum extract | Organic compound | 0.5% | Skin conditioning agent |
Calendula extract | Organic compound | 0.4% | Skin conditioning agent |
Hamamelis mollis extract | Organic compound | 1.5% | Skin conditioning agent |
Matricaria chamomilla extract | Organic compound | 2.3% | Skin conditioning agent |
Propylene glycol | Organic compound | 2% | Humectant type |
Lanolin | Greasy wax | 0.7% | Skin-moistening grease |
Sodium hyaluronate | Glucuronic acid | 0.03% | Humectant type |
Squalane (Squalene) | Hydrocarbon oil and fat | 0.42% | Thickening agent |
Grape seed oil | Organic compound | 0.6% | Skin conditioning agent |
Hydrogenated polydecene | Synthetic polymers | 0.5% | Skin-moistening grease |
。
As a preferable technical scheme of the invention, the calendula emulsion capable of diminishing inflammation and relaxing sensitization is prepared from the following raw materials in parts by weight:
as a preferable technical scheme of the invention, the calendula emulsion capable of diminishing inflammation and relaxing sensitization is prepared from the following raw materials in parts by weight:
raw material name | Variety of raw materials | Dosage of | Purpose of use |
Deionized water | Inorganic material | 79.67% | Solvent(s) |
Glycerol | Organic matter | 10.9% | Humectant type |
Taraxacum mongolicum extract | Organic compound | 2.7% | Skin conditioning agent |
Calendula extract | Organic compound | 3.2% | Skin conditioning agent |
Hamamelis mollis extract | Organic compound | 4.1% | Skin conditioning agent |
Matricaria chamomilla extract | Organic compound | 5.3% | Skin conditioning agent |
Propylene glycol | Organic compound | 8% | Humectant type |
Lanolin | Greasy wax | 2.1% | Skin-moistening grease |
Sodium hyaluronate | Glucuronic acid | 0.13% | Humectant type |
Squalane (Squalene) | Hydrocarbon oil and fat | 0.90% | Thickening agent |
Grape seed oil | Organic compound | 1.9% | Skin conditioning agent |
Hydrogenated polydecene | Synthetic polymers | 1.1% | Skin-moistening grease |
。
As a preferable technical scheme of the invention, the refining process steps of the grape seed oil are as follows:
step one: firstly deacidifying crude grape seed crude oil, controlling initial temperature, slowly dripping alkali liquor to completely saponify free fatty acid, and filtering off fructus Gleditsiae Abnormalis;
step two: adding distilled water isothermal with oil, washing for 1-3 times, wherein the water consumption is 10% -15% of the oil quality each time, standing for 30min after the water is added, discharging waste water, washing until the water solution is neutral, and drying;
step three: placing the hydrated and dried grape seed oil into a flask, adding active carbon with the oil quality of 3% -5%, controlling the temperature at 80-90 ℃, preserving the heat for 30-40 min, and decoloring to obtain the grape seed essential oil.
As a preferable technical scheme of the invention, the preparation method of the calendula emulsion capable of diminishing inflammation and relieving allergy comprises the following steps:
step one: firstly, weighing according to the mass parts of raw materials, namely 68.55 to 79.67 percent of deionized water, 2.5 to 10.9 percent of glycerol, 0.5 to 2.7 percent of dandelion extract, 0.4 to 3.2 percent of calendula extract, 1.5 to 4.1 percent of witch hazel extract, 2.3 to 5.3 percent of chamomile extract, 2 to 8 percent of propylene glycol, 0.7 to 2.1 percent of lanolin, 0.03 to 0.13 percent of sodium hyaluronate, 0.42 to 0.90 percent of squalane, 0.6 to 1.9 percent of grape seed oil and 0.5 to 1.1 percent of hydrogenated polydecene;
step two: adding 68.55 to 79.67 percent of deionized water, 2 to 8 percent of propylene glycol, 0.03 to 0.13 percent of sodium hyaluronate and 0.5 to 1.1 percent of hydrogenated polydecene into a reaction kettle A, stirring and heating to 85 to 90 ℃, and stirring for 15 to 20 minutes for later use to obtain a mixed solution a;
step three: adding 2.5 to 10.9 percent of glycerin, 0.7 to 2.1 percent of lanolin, 0.03 to 0.13 percent of sodium hyaluronate, 0.42 to 0.90 percent of squalane and 0.6 to 1.9 percent of grape seed oil into a reaction kettle B, stirring and heating to 70 to 80 ℃, and preserving heat and stirring until the mixture is completely dissolved to obtain a mixed solution B;
step four: vacuum stirring, holding vacuum at 0.03Mpa, placing the mixed solution a and the mixed solution b in an emulsifying pot, stirring, homogenizing at high speed for 5-8 min, and stirring under vacuum for 10-15 min;
step five: and (3) gradually pouring 0.5% -2.7% of dandelion extract, 0.4% -3.2% of calendula extract, 1.5% -4.1% of witch hazel extract and 2.3% -5.3% of chamomile extract into the mixed solution after the temperature of the mixed solution in the step four is reduced to 30-45 ℃, stirring for 30-35 min, discharging and standing to obtain calendula emulsion.
Compared with the prior art, the invention has the beneficial effects that: the calendula emulsion capable of diminishing inflammation and relieving allergy comprises dandelion extract and chamomile extract, wherein the dandelion extract has the effects of clearing heat and detoxicating, maintaining beauty, keeping young, resisting bacteria and diminishing inflammation, can reduce the effect of inflammation in skin, and remove facial vaccinia, so that the effects of repairing skin horny layer, maintaining water-oil balance, relieving allergy and the like are achieved.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention provides calendula emulsion capable of diminishing inflammation and relieving allergy:
embodiment one: the calendula emulsion capable of diminishing inflammation and relieving allergy is prepared from the following raw materials in parts by weight:
raw material name | Variety of raw materials | Dosage of | Purpose of use |
Deionized water | Inorganic material | 68.55% | Solvent(s) |
Glycerol | Organic compound | 2.5% | Humectant type |
Taraxacum mongolicum extract | Organic compound | 0.5% | Skin conditioning agent |
Calendula extract | Organic compound | 0.4% | Skin conditioning agent |
Hamamelis mollis extract | Organic compound | 1.5% | Skin conditioning agent |
Matricaria chamomilla extract | Organic compound | 2.3% | Skin conditioning agent |
Propylene glycol | Organic compound | 2% | Humectant type |
Lanolin | Greasy wax | 0.7% | Skin-moistening grease |
Sodium hyaluronate | Glucuronic acid | 0.03% | Humectant type |
Squalane (Squalene) | Hydrocarbon oil and fat | 0.42% | Thickening agent |
Grape seed oil | Organic compound | 0.6% | Skin conditioning agent |
Hydrogenated polydecene | Synthetic polymers | 0.5% | Skin-moistening grease |
The preparation method of the calendula emulsion capable of diminishing inflammation and relieving allergy comprises the following steps:
step one: firstly, weighing according to the mass parts of raw materials, namely 68.55 percent of deionized water, 2.5 percent of glycerol, 0.5 percent of dandelion extract, 0.4 percent of calendula extract, 1.5 percent of witch hazel extract, 2.3 percent of chamomile extract, 2 percent of propylene glycol, 0.7 percent of lanolin, 0.03 percent of sodium hyaluronate, 0.42 percent of squalane, 0.6 percent of grape seed oil and 0.5 percent of hydrogenated polydecene;
step two: adding 68.55% of deionized water, 2% of propylene glycol, 0.03% of sodium hyaluronate and 0.5% of hydrogenated polydecene into a reaction kettle A, stirring and heating to 85-90 ℃, and stirring for 15-20 min to obtain a mixed solution a;
step three: adding 2.5% of glycerin, 0.7% of lanolin, 0.03% of sodium hyaluronate, 0.42% of squalane and 0.6% of grape seed oil into a reaction kettle B, stirring and heating to 70-80 ℃, and keeping the temperature and stirring until the mixture is completely dissolved to obtain a mixed solution B;
step four: vacuum stirring, holding vacuum at 0.03Mpa, placing the mixed solution a and the mixed solution b in an emulsifying pot, stirring, homogenizing at high speed for 5-8 min, and stirring under vacuum for 10-15 min;
step five: and (3) gradually pouring 0.5% of dandelion extract, 0.4% of calendula extract, 1.5% of witch hazel extract and 2.3% of chamomile extract into the mixed solution after the temperature of the mixed solution in the step four is reduced to 30-45 ℃, stirring for 30-35 min, discharging and standing to obtain calendula emulsion.
Embodiment two: the calendula emulsion capable of diminishing inflammation and relieving allergy is prepared from the following raw materials in parts by weight:
the preparation method of the calendula emulsion capable of diminishing inflammation and relieving allergy comprises the following steps:
step one: firstly, weighing according to the mass parts of raw materials, namely 74.06 percent of deionized water, 6.7 percent of glycerol, 1.6 percent of dandelion extract, 1.8 percent of calendula extract, 2.8 percent of witch hazel extract, 3.8 percent of chamomile extract, 5 percent of propylene glycol, 1.4 percent of lanolin, 0.08 percent of sodium hyaluronate, 0.66 percent of squalane, 1.3 percent of grape seed oil and 0.8 percent of hydrogenated polydecene;
step two: adding 74.06% of deionized water, 5% of propylene glycol, 0.08% of sodium hyaluronate and 0.8% of hydrogenated polydecene into a reaction kettle A, stirring and heating to 85-90 ℃, and stirring for 15-20 min to obtain a mixed solution a;
step three: adding 6.7% of glycerin, 1.4% of lanolin, 0.08% of sodium hyaluronate, 0.66% of squalane and 1.3% of grape seed oil into a reaction kettle B, stirring and heating to 70-80 ℃, and keeping the temperature and stirring until the mixture is completely dissolved to obtain a mixed solution B;
step four: vacuum stirring, holding vacuum at 0.03Mpa, placing the mixed solution a and the mixed solution b in an emulsifying pot, stirring, homogenizing at high speed for 5-8 min, and stirring under vacuum for 10-15 min;
step five: and (3) gradually pouring 1.6% of dandelion extract, 1.8% of calendula extract, 2.8% of witch hazel extract and 3.8% of chamomile extract into the mixed solution after the temperature of the mixed solution in the step four is reduced to 30-45 ℃, stirring for 30-35 min, discharging and standing to obtain calendula emulsion.
Embodiment III:
the calendula emulsion capable of diminishing inflammation and relieving allergy is prepared from the following raw materials in parts by weight:
the preparation method of the calendula emulsion capable of diminishing inflammation and relieving allergy comprises the following steps:
step one: firstly, weighing 79.67% of deionized water, 10.9% of glycerol, 2.7% of dandelion extract, 3.2% of calendula extract, 4.1% of witch hazel extract, 5.3% of chamomile extract, 8% of propylene glycol, 2.1% of lanolin, 0.13% of sodium hyaluronate, 0.90% of squalane, 1.9% of grape seed oil and 1.1% of hydrogenated polydecene according to the mass parts of raw materials;
step two: adding 79.67% of deionized water, 8% of propylene glycol, 0.13% of sodium hyaluronate and 1.1% of hydrogenated polydecene into a reaction kettle A, stirring and heating to 85-90 ℃, and stirring for 15-20 min to obtain a mixed solution a;
step three: adding 10.9% of glycerin, 2.1% of lanolin, 0.13% of sodium hyaluronate, 0.90% of squalane and 1.9% of grape seed oil into a reaction kettle B, stirring and heating to 70-80 ℃, and keeping the temperature and stirring until the mixture is completely dissolved to obtain a mixed solution B;
step four: vacuum stirring, holding vacuum at 0.03Mpa, placing the mixed solution a and the mixed solution b in an emulsifying pot, stirring, homogenizing at high speed for 5-8 min, and stirring under vacuum for 10-15 min;
step five: and (3) gradually pouring 2.7% of dandelion extract, 3.2% of calendula extract, 4.1% of witch hazel extract and 5.3% of chamomile extract into the mixed solution after the temperature of the mixed solution in the step (IV) is reduced to 30-45 ℃, stirring for 30-35 min, discharging and standing to obtain calendula emulsion.
The refining process of the grape seed oil comprises the following steps:
step one: firstly deacidifying crude grape seed crude oil, controlling initial temperature, slowly dripping alkali liquor to completely saponify free fatty acid, and filtering off fructus Gleditsiae Abnormalis;
step two: adding distilled water isothermal with oil, washing for 1-3 times, wherein the water consumption is 10% -15% of the oil quality each time, standing for 30min after the water is added, discharging waste water, washing until the water solution is neutral, and drying;
step three: placing the hydrated and dried grape seed oil into a flask, adding active carbon with the oil quality of 3% -5%, controlling the temperature at 80-90 ℃, preserving the heat for 30-40 min, and decoloring to obtain the grape seed essential oil.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The calendula emulsion capable of diminishing inflammation and relieving allergy is characterized by comprising the following raw materials in parts by weight:
。
2. An anti-inflammatory allergy-free calendula emulsion according to claim 1, wherein: the calendula emulsion capable of diminishing inflammation and relieving allergy is prepared from the following raw materials in parts by weight:
3. an anti-inflammatory allergy-free calendula emulsion according to claim 1, wherein: the calendula emulsion capable of diminishing inflammation and relieving allergy is prepared from the following raw materials in parts by weight:
。
4. An anti-inflammatory allergy-free calendula emulsion according to claim 1, wherein: the calendula emulsion capable of diminishing inflammation and relieving allergy is prepared from the following raw materials in parts by weight:
5. an anti-inflammatory allergy-free calendula emulsion according to claim 1, wherein: the refining process of the grape seed oil comprises the following steps:
step one: firstly deacidifying crude grape seed crude oil, controlling initial temperature, slowly dripping alkali liquor to completely saponify free fatty acid, and filtering off fructus Gleditsiae Abnormalis;
step two: adding distilled water isothermal with oil, washing for 1-3 times, wherein the water consumption is 10% -15% of the oil quality each time, standing for 30min after the water is added, discharging waste water, washing until the water solution is neutral, and drying;
step three: placing the hydrated and dried grape seed oil into a flask, adding active carbon with the oil quality of 3% -5%, controlling the temperature at 80-90 ℃, preserving the heat for 30-40 min, and decoloring to obtain the grape seed essential oil.
6. An anti-inflammatory allergy-free calendula emulsion according to claim 1, wherein: the preparation method of the calendula emulsion capable of diminishing inflammation and relieving allergy comprises the following steps:
step one: firstly, weighing according to the mass parts of raw materials, namely 68.55 to 79.67 percent of deionized water, 2.5 to 10.9 percent of glycerol, 0.5 to 2.7 percent of dandelion extract, 0.4 to 3.2 percent of calendula extract, 1.5 to 4.1 percent of witch hazel extract, 2.3 to 5.3 percent of chamomile extract, 2 to 8 percent of propylene glycol, 0.7 to 2.1 percent of lanolin, 0.03 to 0.13 percent of sodium hyaluronate, 0.42 to 0.90 percent of squalane, 0.6 to 1.9 percent of grape seed oil and 0.5 to 1.1 percent of hydrogenated polydecene;
step two: adding 68.55 to 79.67 percent of deionized water, 2 to 8 percent of propylene glycol, 0.03 to 0.13 percent of sodium hyaluronate and 0.5 to 1.1 percent of hydrogenated polydecene into a reaction kettle A, stirring and heating to 85 to 90 ℃, and stirring for 15 to 20 minutes for later use to obtain a mixed solution a;
step three: adding 2.5 to 10.9 percent of glycerin, 0.7 to 2.1 percent of lanolin, 0.03 to 0.13 percent of sodium hyaluronate, 0.42 to 0.90 percent of squalane and 0.6 to 1.9 percent of grape seed oil into a reaction kettle B, stirring and heating to 70 to 80 ℃, and preserving heat and stirring until the mixture is completely dissolved to obtain a mixed solution B;
step four: vacuum stirring, holding vacuum at 0.03Mpa, placing the mixed solution a and the mixed solution b in an emulsifying pot, stirring, homogenizing at high speed for 5-8 min, and stirring under vacuum for 10-15 min;
step five: and (3) gradually pouring 0.5% -2.7% of dandelion extract, 0.4% -3.2% of calendula extract, 1.5% -4.1% of witch hazel extract and 2.3% -5.3% of chamomile extract into the mixed solution after the temperature of the mixed solution in the step four is reduced to 30-45 ℃, stirring for 30-35 min, discharging and standing to obtain calendula emulsion.
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