CN117092174A - Disposable sweat detection reagent card and application method thereof - Google Patents
Disposable sweat detection reagent card and application method thereof Download PDFInfo
- Publication number
- CN117092174A CN117092174A CN202311096253.9A CN202311096253A CN117092174A CN 117092174 A CN117092174 A CN 117092174A CN 202311096253 A CN202311096253 A CN 202311096253A CN 117092174 A CN117092174 A CN 117092174A
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- Prior art keywords
- reagent card
- detection
- sweat
- channel
- card body
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 80
- 210000004243 sweat Anatomy 0.000 title claims abstract description 76
- 238000001514 detection method Methods 0.000 title claims abstract description 72
- 238000000034 method Methods 0.000 title claims description 16
- 238000012544 monitoring process Methods 0.000 claims abstract description 22
- 239000012482 calibration solution Substances 0.000 claims abstract description 20
- 238000003825 pressing Methods 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 4
- 238000003860 storage Methods 0.000 claims description 3
- 230000035900 sweating Effects 0.000 claims description 2
- 239000000758 substrate Substances 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 13
- 239000010408 film Substances 0.000 description 9
- 235000014655 lactic acid Nutrition 0.000 description 7
- 239000004310 lactic acid Substances 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 5
- 229920000742 Cotton Polymers 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000036541 health Effects 0.000 description 3
- 238000011176 pooling Methods 0.000 description 3
- 238000011897 real-time detection Methods 0.000 description 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000002207 metabolite Substances 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000000090 biomarker Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004159 blood analysis Methods 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
Abstract
The disposable reagent card for sweat real-time monitoring provided by the invention can be independently stuck on the skin or can be matched with a binding belt to be stuck on the skin, so that one item detection or simultaneous detection of multiple items can be realized according to the requirement. The reagent card comprises an upper detection circuit module layer and a lower reagent card body patch. The lower reagent card body is designed to be a biosensor with the right side facing upwards and is designed with an upper micro-channel, a lower micro-channel and a calibration area, so that an air cavity caused by strong hydrophobicity of the surface of the biosensor and a thinner sweat cavity can be avoided; the calibration area stores a calibration solution, and the calibration solution is used for calibrating the reagent card and the detection module, so that the reagent card and the detection module are in an optimal state to be detected.
Description
Technical Field
The invention relates to the technical field of medical instruments and microfluidics for detecting sweat in real time by an electrochemical method, in particular to a disposable reagent card for sweat detection and a use method thereof.
Background
It is well known that human sweat contains a large amount of physiological metabolites, while sweat gland activity is related to blood circulation supply, and the concentration of each physiological substance in sweat is greatly related to the physiological level in blood plasma, so that the overall health condition of human can be analyzed by measuring biomarkers in sweat. A non-invasive dynamic health monitoring method may be provided by the wearable sensor transitioning from blood analysis to in situ sweat analysis.
In recent years, with the development of thin film technology, wearable sensors gain attention of more researchers. The electrochemical sensor has the advantages of high performance, miniaturization, low cost and the like, and provides considerable prospect for the development of the wearable chemical sensor. Various wearable electrochemical biosensors have been developed by researchers to monitor electrolytes (sodium, potassium, calcium, chlorine, pH, etc.) and metabolites (e.g., glucose, lactic acid, urea, etc.) of sweat in real time non-invasively to indicate the health of the wearer.
The biochemical indexes are monitored by adopting a miniature electrochemical sensor, a biosensing substance is fixed on the surface of the sensor as a molecular identifier, target analysis is captured on the surface of an electrode through the specific recognition function among molecules, and a concentration signal is converted into a measurable electric signal such as potential, current, resistance or capacitance by a basic electrode inside the sensor as a response signal, so that quantitative or qualitative analysis of the target analyte is realized. Due to its own characteristics, such electrodes must generally be kept in a vertical position during use, and the monitoring is performed while avoiding poor contact and avoiding bubbles on the sensor surface. In addition, the sensor manufactured in the same batch can be stored for a long time, so that the surface of the sensitive film can be gradually changed, and the initial potential value or the current value and the like can be greatly different when the sensor is used, and the test result can be greatly different. However, the wearable devices or sensors currently used for biochemical monitoring generally do not consider the problems, and the detection results are easy to deviate and inaccurate.
Disclosure of Invention
The invention mainly aims to provide a calibratable disposable wearable sensor reagent card for sweat real-time monitoring and a use method thereof, and aims to solve the technical problems that an air cavity is easy to form on the surface of a sensor and the reagent card cannot be calibrated conveniently in the existing wearable sweat detection technology.
Based on the above purpose, the invention provides a disposable wearable sensor reagent card for sweat real-time monitoring, the reagent card comprises an upper layer and a lower layer, the upper layer is a detection circuit module layer, the lower layer is a reagent card body patch, the body patch is provided with an upper micro-channel and a lower micro-channel, the lower micro-channel is used for collecting sweat, the upper micro-channel is used for sweat real-time detection, the upper micro-channel and the lower micro-channel are connected through micropores, and the whole structure can effectively avoid the existence of an air cavity in the detection channel; the body is pasted and is equipped with the calibration area, stores the calibration liquid, can calibrate detection circuitry and biosensor through the calibration liquid, makes to reach the optimal state.
Further, the upper layer of the reagent card is a detection circuit module layer, and the reagent card can be fixed on the reagent card body through a buckle, and a circuit formed by electronic devices is arranged, so that the reagent card has a detection function and a communication function.
Further, the detection circuit of the detection module is provided with a gold-plated probe, can be tightly connected with the sensor contact attached to the reagent card body, and collects signals.
Further, the lower layer of the reagent card is a reagent card body patch, an upper micro-channel and a lower micro-channel are arranged, the lower micro-channel is used for collecting sweat, and the upper micro-channel is used for sweat detection.
Further, the lower channel of the reagent card body paste consists of a semicircular collecting area consisting of sweat collecting holes, a plurality of small channels and a plurality of main channels, a middle sweat collecting area and an upper hydrophilic film layer, and sweat is promoted to flow into the collecting area through capillary action of the channels.
Furthermore, the joint of the lower channel, the small channel and the main channel of the reagent card body is provided with a plurality of round areas, so that more sweat can be conveniently collected.
Further, the upper channel of the reagent card body patch is a sensor detection channel formed by a sensor plate, an upper hydrophilic film and a partition plate, sweat flows into the upper channel from a sweat collecting area through micropores, and sweat monitoring can be performed in real time.
Further, the upper channel sensor plate of the reagent card body patch is provided with different micro-biosensors, and the front surface of each biosensor faces upwards, so that different types and numbers of the biosensors can be designed according to the requirements.
Further, the upper hydrophilic film of the upper channel of the reagent card body patch is provided with an air outlet, and the outside of the air outlet is in close contact with the sweat collector, namely the fiber absorbent cotton layer, for collecting redundant sweat.
Furthermore, a calibration area is designed beside the channel attached to the reagent card body, and a calibration solution is stored for calibrating the reagent card and the detection module.
Furthermore, the reagent card body is attached to the calibration area, and the calibration solution can flow into the upper channel in a pressing mode to perform calibration.
The invention also includes a method of using a disposable calibratable reagent card for sweat detection, the method being implemented using a reagent card for sweat detection as described above, the method comprising: s1: preparing for monitoring: and the detection circuit module is arranged on the reagent card body to form the reagent card. Pressing the calibration area for calibration, enabling the calibration solution to enter the detection channel, triggering the equipment, starting the equipment, and performing self-checking calibration. After calibration is completed, the reagent card is stuck on the skin and ready for real-time detection.
S2: detection starts: the detected person starts to move or the skin is stimulated to start sweating, and the reagent card automatically collects sweat for real-time monitoring. In the detection process, detection data can be checked through the mobile phone App.
S3: and (3) detection is finished: the detection module can be directly detached, and the reagent card paste can be directly discarded.
According to the reagent card for sweat monitoring, the calibration area and the micro-channel detection area are arranged on the reagent card at the same time, the calibration solution storage cavity can store the calibration solution, the micro-channel detection area can directly collect sweat and detect multiple items through self-flowing of the micro-channel sweat, so that the reagent card can ensure that calibration and sweat collection and detection can be realized, transportation and carrying are convenient, the electrochemical biosensor in the reagent card is automatically calibrated through the calibration solution before detection, the use is extremely convenient, and the detection result is more accurate.
Drawings
FIG. 1 is a block diagram of the micro-channels of sweat collection of the present invention.
FIG. 2 is a schematic diagram of the upper hydrophilic membrane layer of the microchannel of the invention.
Fig. 3 is a top plan view of the reagent card body of the present invention.
Fig. 4 is a biosensor detection channel of the present invention.
Fig. 5 is a cross-sectional view of the invention taken along the A-A plane of fig. 3.
FIG. 6 is a cyclic voltammetric scan of an individual lactate sensor in accordance with the present invention.
FIG. 7 is a graph of real-time detection of a lactic acid sweat card of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. It is to be understood that the described embodiments are merely some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be noted that all directional indicators (such as up, down, left, right, front, and rear … …) in the embodiments of the present invention are merely used to explain the relative positional relationship, movement, etc. between the components in a particular posture (as shown in the drawings), and if the particular posture is changed, the directional indicator is changed accordingly.
Furthermore, the description of "first," "second," etc. in this disclosure is for descriptive purposes only and is not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present invention.
It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
Referring to fig. 1-5, the disposable reagent card for sweat real-time monitoring provided by the invention can be independently attached to skin or can be matched with a binding belt to be attached to skin, so that one item detection or simultaneous detection of multiple items can be realized according to requirements.
Specifically, the reagent card comprises an upper detection circuit module layer (18) and a lower reagent card body patch (7). The lower layer reagent card body is provided with an upper micro-channel, a lower micro-channel and a calibration area, wherein the upper micro-channel and the lower micro-channel are communicated through small holes (6 and 11), the surface of the channel is covered with a hydrophilic film (21), and sweat can automatically flow into the upper channel (13) from the lower channel collecting area (4) through the small holes (24 and 11) for sweat detection; the calibration area (8) stores a calibration solution (9) used for calibrating the reagent card and the detection module so that the reagent card and the detection module are in an optimal state to be detected.
The invention is not limited to components of the calibration solution, as long as the calibration of the reagent card and the detection module can be realized, for example, the calibration solution can be prepared from standard substances such as sodium chloride, potassium chloride, lactic acid and the like and buffer solution.
In one embodiment, the reagent card body patch is composed of upper and lower channels, the lower layer is a sweat collecting region, and preferably, referring to fig. 1 and 2, is composed of a semicircular collecting region composed of sweat collecting holes (22), a plurality of small channels (1), a plurality of main channels (2), an intermediate sweat collecting region (4) and an upper hydrophilic film layer. The human body can produce a large amount of sweat when moving or receiving the stimulus, and sweat can be gathered sweat collection district by sweat collecting hole, minichannel and main channel respectively, is equipped with many circular regions (3) in minichannel and main channel junction, is convenient for collect more sweat more. The capillary action of the small channels and the main channels promotes sweat flow into the pooling area, and the hydrophilic film layer thereon promotes sweat pooling. Sweat upper and lower channel communicating apertures (24) are designed on the right side of the pooling area through which sweat continuously flows into the upper channel. This process does not allow air bubbles during sweat collection to flow into the upper channels. The reagent card body patch can be firmly adhered to the skin by (5) a porous adhesive.
In one embodiment, the reagent card body mounting channel is a sensor detection channel, preferably referring to fig. 3 and 5, sweat flows from the sweat collecting region into the upper channel (13) through the small holes (24) and (11), and sweat monitoring can be performed in real time. The sensor plate (20), the upper hydrophilic film (15) and the partition plate (16) form a sensor detection channel. The biosensor (12) is designed on the sensor board, the right side is upward, and different types and numbers of biosensors can be designed according to the requirements. As shown in FIG. 5, sweat flows from the apertures (24 and 11) to the upper channel (13) and over the biosensor (12), thus avoiding the formation of an air cavity over the hydrophobic membrane of the sensor, and the distal end of the upper hydrophilic membrane layer has an air outlet (17) out of which is a fibrous absorbent cotton layer (25) that is tightly connected to the air outlet and can be used to collect excess sweat. The sweat channel with small aperture, the double-layer hydrophilic film layer, the design of small hole drilling and the fiber water-absorbing cotton layer can enable sweat to continuously flow in for real-time monitoring.
In one embodiment, referring to fig. 4, a calibration area (8) is provided adjacent to the upper layer channel of the reagent card body, and a calibration solution (9) is stored, wherein the calibration solution is used for calibrating the reagent card and the detection module. In preparation for monitoring after installation, the biosensor (12) is calibrated by pressing by hand, causing a calibration solution to flow into the detection channel through the microchannel (23). The micro-channel (23) is provided with a valve design, the valve can be opened only by pressing, and the solution flows out. After calibration is completed and pressed again, the calibration solution will flow into the sweat fibrous absorbent cotton layer (25).
The detection circuit module can be mounted on the reagent card body through a buckle. The detection circuit module layer (18) is provided with a micro probe (19) which can be closely contacted with a biosensor contact (14) in the lower reagent card body patch. After the detection is finished, the detection circuit module can be taken down for reuse, and the reagent card body layer paste can be directly discarded.
The invention also provides a detection method for sweat real-time monitoring, which is realized by adopting the reagent card, and the specific method comprises the following steps: s1: preparing for monitoring: and the detection circuit module is arranged on the reagent card body to form the reagent card. Pressing the calibration area to calibrate, enabling the calibration solution to enter the detection channel, and triggering. Starting the device, and performing self-checking calibration. After calibration is completed, the reagent card is stuck to the skin and ready for detection.
S2: detection starts: the detected person starts to move or skin irritation starts to sweat, and the reagent card automatically collects sweat for monitoring. In the detection process, detection data can be seen in real time through the mobile phone App.
S3: and (3) detection is finished: the detection module can be directly detached, and the reagent card paste can be directly discarded.
In one embodiment, referring to fig. 6, an embodiment of individual sweat lactic acid item monitoring is provided. Cyclic voltammetric scans of simulated sweat for different lactic acids with a single enzyme-free lactate sensor. It can be seen that the enzyme-free lactate sensor alone has a specific response to different lactate concentrations at-0.15V.
In one embodiment, referring to fig. 7, an embodiment of individual sweat lactic acid item monitoring is provided. Real time monitoring graph of real sweat tested by enzyme-free lactate sensor alone. The lactic acid electrode current value was monitored for 1.5h (5400 s) at a constant potential of-0.15V.
The foregoing description is only of the preferred embodiments of the present invention and is not intended to limit the scope of the invention, and all equivalent structures or equivalent processes using the descriptions and drawings of the present invention or directly or indirectly applied to other related technical fields are included in the scope of the invention.
Claims (8)
1. A disposable reagent card for sweat detection is characterized by comprising a reagent card body patch, wherein an upper micro-channel, a lower micro-channel and a calibration area are arranged on the reagent card body patch and used for sweat collection and detection, micropores are arranged at the joint of the upper micro-channel and the lower micro-channel, the calibration area comprises a calibration solution storage cavity, and a calibration solution is stored in the calibration solution storage cavity.
2. The reagent card body patch of claim 1, wherein the reagent card body patch is provided with micro-holes communicating with the upper and lower micro-channels.
3. The reagent card body patch of claim 1, wherein the reagent card body patch is provided with a lower channel, and the lower channel comprises a sweat collecting region and a sweat collecting region formed by sweat collecting holes, small channels, a main channel and an upper hydrophilic film layer.
4. The reagent card body patch of claim 1, wherein the reagent card body patch is provided with an upper channel, and is composed of a sensor substrate, a separator, and a hydrophilic film layer.
5. A reagent card body patch according to claim 3, wherein the lower channel is provided with a plurality of circular areas connecting the main channel and the mini-channels.
6. The reagent card body patch of claim 4, wherein the upper channel sensor substrate is provided with a right-side-up micro-biosensor.
7. The reagent card body patch of claim 4, wherein the hydrophilic membrane layer has air holes at a distal end thereof, the air holes being connected to an external sweat collector.
8. A detection method for sweat detection, characterized in that the method is implemented with a reagent card for sweat detection as claimed in any one of claims 1 to 7, the method comprising:
s1: preparing for monitoring: and the detection circuit module is arranged on the reagent card body to form the reagent card. Pressing the calibration area for calibration, enabling the calibration solution to enter the detection channel, triggering the equipment, starting the equipment, and performing self-checking calibration. After calibration is completed, the reagent card is stuck to the skin and ready for detection. S2: detection starts: the detected person starts to move or the skin is stimulated to start sweating, and the reagent card automatically collects sweat for real-time monitoring. In the detection process, detection data can be checked through the mobile phone App. S3: and (3) detection is finished: the detection module can be directly detached, and the reagent card paste can be directly discarded.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311096253.9A CN117092174A (en) | 2023-08-29 | 2023-08-29 | Disposable sweat detection reagent card and application method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311096253.9A CN117092174A (en) | 2023-08-29 | 2023-08-29 | Disposable sweat detection reagent card and application method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117092174A true CN117092174A (en) | 2023-11-21 |
Family
ID=88774877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311096253.9A Pending CN117092174A (en) | 2023-08-29 | 2023-08-29 | Disposable sweat detection reagent card and application method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117092174A (en) |
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2023
- 2023-08-29 CN CN202311096253.9A patent/CN117092174A/en active Pending
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