CN116679074A - Sample detection method, system, detector and medium - Google Patents

Sample detection method, system, detector and medium Download PDF

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Publication number
CN116679074A
CN116679074A CN202310485235.3A CN202310485235A CN116679074A CN 116679074 A CN116679074 A CN 116679074A CN 202310485235 A CN202310485235 A CN 202310485235A CN 116679074 A CN116679074 A CN 116679074A
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China
Prior art keywords
sample
detection
area
test
sample container
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CN202310485235.3A
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Chinese (zh)
Inventor
张旭
刘晓彬
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Zhongyuan Huiji Biotechnology Co Ltd
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Zhongyuan Huiji Biotechnology Co Ltd
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Priority to CN202310485235.3A priority Critical patent/CN116679074A/en
Publication of CN116679074A publication Critical patent/CN116679074A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011Control of the position or alignment of the transfer device
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00821Identification of carriers, materials or components in automatic analysers nature of coded information
    • G01N2035/00831Identification of carriers, materials or components in automatic analysers nature of coded information identification of the sample, e.g. patient identity, place of sampling
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0474Details of actuating means for conveyors or pipettes
    • G01N2035/0491Position sensing, encoding; closed-loop control

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The application discloses a sample detection system, which is characterized in that a sample container in a pre-stored area is moved to a test area, a sample sucking operation is performed at a designated position of the test area through a sample sucking module, samples in the sample container are sucked away, and then a dry chemical test is performed; after all the dry chemical tests of the samples to be tested in all the sample containers are completed, analyzing whether the samples in the sample containers are positive, if the dry chemical results are negative, not moving the sample containers, and ending the test; if the dry chemical result is positive, namely at least one abnormal detection result exists, the sample container is moved to a test area, a sample sucking module sucks samples again at the designated position of the test area, and then a component forming test is performed; according to the method, when the dry chemical is positive, the sample to be tested is retransmitted back to the test area for sample suction operation, so that the positive patient can be prevented from providing the sample to be tested again, and the trouble of the positive patient is reduced.

Description

Sample detection method, system, detector and medium
Technical Field
The application relates to the field of medical instruments, in particular to a sample detection method, a system, a detector and a computer storage medium.
Background
Sample analysis generally refers to processing a sample such as blood, urine, etc., and detecting and analyzing the processed result by using some detection means (such as optical means), and obtaining an analysis result.
When the urine sample is analyzed, the urine sample can be detected by two different detection methods, namely dry chemistry and shaped, and the specific condition of the urine sample is comprehensively judged by the two detection methods. Specifically, the sample analyzer will draw a urine sample with a sample needle, transport the sample to a dry chemical detection module (typically a test strip), and simultaneously transport the sample to a patterned detection module for detection.
The urine detector in the current market has two modes of a dry chemical test and a formed component test, wherein the dry chemical test is qualitative analysis (negative or positive), the test cost is lower, and the clinical significance is smaller than that of the formed component test; the component test is quantitative analysis, so that the specific content of a certain cell in urine can be analyzed, the test cost is high, and the clinical significance is high; the patient may choose to conduct the dry chemical test alone, the formed component test alone, and both modes of testing simultaneously.
On the one hand, the patient can choose to perform independent dry chemical tests, and if the detection result is positive, the patient is usually required to perform a forming component test again; on the other hand, most patients in the hospital can choose to test in two modes simultaneously, if the results are all negative, the formation test is not needed to be seen, and the dry chemical test results of most patients in the hospital are positive products, namely all negative, if the two modes are selected to test simultaneously, the greater cost waste is generated in the test process.
Disclosure of Invention
In view of the above-mentioned drawbacks of the prior art, an object of the present application is to provide a sample detection method, system, detector and computer storage medium for solving the drawbacks of the prior art.
To achieve the above and other related objects, the present application provides a sample detection system including a sample detection device including:
the pre-storing area is used for carrying a sample container, and the sample container is used for containing a sample to be tested;
the test area is used for executing sample sucking operation on the sample to be detected in the sample container transmitted from the pre-storing area, and the sample sucking operation is performed through a sample sucking module;
a recovery zone for receiving the sample containers transferred from the test zone;
a controller for controlling the sample transfer module to perform transfer control on the sample container, the transfer control comprising:
transferring the sample container from the pre-storage area to the test area, transferring the sample container from the test area to the recovery area, and transferring the sample container from the recovery area to the pre-storage area or transferring the sample container from the recovery area to the test area;
the first detection module is used for responding to a first control instruction of the controller to detect one or more samples to be detected sucked by the sample sucking module in a first detection mode to obtain one or more first detection results, and if the one or more first detection results are normal detection results, the detection is finished; the sample container is used for storing a plurality of samples to be detected, wherein the samples to be detected are detected in a first detection mode, and the samples to be detected are transmitted to the test area from the pre-storage area;
the second detection module is used for responding to a second control instruction of the controller to detect one or more abnormal samples sucked by the sample suction module in a second detection mode to obtain one or more second detection results; the second control instruction is generated when at least one abnormal detection result is included in the plurality of first detection results, the abnormal sample is a sample corresponding to the abnormal detection result, and the abnormal sample is sucked from a sample container located in the recovery area.
In an embodiment of the present application, the sample detection device further includes:
and the information detection module is used for detecting the labels on the sample containers to obtain patient information corresponding to each sample container and obtain first patient information.
In an embodiment of the present application, the sample detection device further includes:
the position detection module is used for detecting whether a sample container exists or not, detecting the position and the number of the sample containers, and obtaining first position information, wherein the first position information comprises the number information of the sample containers and the position information of each sample container.
In an embodiment of the present application, the controller controls the position detection module to detect a sample container corresponding to the abnormality detection result to obtain second position information, and controls the information detection module to detect a label of the sample container corresponding to the abnormality detection result to obtain second patient information; the controller determines whether the sample container corresponding to the abnormality detection result is an abnormal sample container according to the first position information, the second position information, the first patient information, and the second patient information.
In an embodiment of the present application, the first detection mode is a dry chemical test, and the second detection mode is a formed component test.
In an embodiment of the present application, the test area includes a sample sucking position, and the controller controls the sample container to move from the pre-storing area to the test area, and controls the sample container to stay on the sample sucking position in sequence, so that the sample sucking module is used for executing a sample sucking operation on a sample to be tested in the sample container on the sample sucking position.
In an embodiment of the present application, the sample detection system includes a plurality of sample detection devices having an online relationship, where the online relationship indicates that when a first detection result output by one of the sample detection devices is an abnormal detection result, the abnormal sample is transmitted to the other sample detection devices, so that a second detection module of the sample detection device that receives the abnormal sample performs sample detection based on the abnormal sample.
In one embodiment of the present application, the sample transmission module includes a first transmission track and a second transmission track,
the first transmission track is used for transmitting the sample container from the pre-storing area to the testing area in a first direction, transmitting the sample container from the testing area to the recycling area in the first direction and transmitting the sample container from the recycling area to the testing area in a second direction;
the second transmission track is used for transmitting the sample container from the recovery area to the pre-storage area in a second direction;
wherein the first direction and the second direction are opposite directions to each other.
To achieve the above and other related objects, the present application provides a sample detection method applied to the sample detection system, the sample detection method comprising:
controlling the sample container to move from the pre-storing area to the testing area;
sequentially carrying out sample sucking operation on samples to be tested in one or more sample containers in a test area through a sample sucking module to obtain one or more first samples;
controlling the sample container to move from the test zone to the recovery zone;
sample detection is carried out on the one or more first samples in a first detection mode, so that one or more first detection results are obtained;
judging whether the first detection result contains an abnormal detection result or not, and if one or more first detection results are all normal detection results, ending the detection; if the one or more first detection results comprise at least one abnormal detection result, moving the sample container in the recovery area to the test area or moving the sample container in the recovery area to the pre-stored area and then moving the sample container in the recovery area to the test area through the pre-stored area;
sequentially sucking abnormal samples from sample containers corresponding to abnormal detection results through a sample sucking module in a test area to obtain one or more second samples;
and carrying out sample detection on the one or more second samples in a second detection mode to obtain one or more first detection results.
To achieve the above and other related objects, the present application provides a sample detector comprising:
one or more processors;
and a storage means for storing one or more programs which, when executed by the one or more processors, cause the electronic device to implement the steps of the sample detection method.
To achieve the above and other related objects, the present application provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor of a computer, causes the computer to perform the steps of the sample detection method.
As described above, the sample detection method, the system and the detector computer storage medium have the following beneficial effects:
the sample detection system provided by the application is characterized in that a sample container in a pre-stored area is moved to a test area, a sample sucking operation is performed at a designated position of the test area through a sample sucking module, a sample in the sample container is sucked away, then a dry chemical test is performed, and after the sample sucking module sucks the sample, the sample container is moved to a recovery area; after all the dry chemical tests of the samples to be tested in all the sample containers are completed, analyzing whether the samples in the sample containers have abnormal samples or not, namely, if the results are positive, if the dry chemical results are negative, the sample containers are not moved, and the test is finished; if the dry chemical result is positive, namely at least one abnormal detection result exists, the sample container is moved to a test area, a sample sucking module sucks samples again at the designated position of the test area, and then a component forming test is performed; according to the method, when the dry chemical is positive, the sample to be tested is retransmitted to the test area for sample suction operation, so that a positive patient can be prevented from providing the sample to be tested again, the trouble of the positive patient is reduced, meanwhile, the detection flow is ended when the first detection result is negative, and the additional cost caused by the detection of the formed component is saved.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application as claimed.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the application and together with the description, serve to explain the principles of the application. It is evident that the drawings in the following description are only some embodiments of the present application and that other drawings may be obtained from these drawings without inventive effort for a person of ordinary skill in the art. In the drawings:
FIG. 1 is a schematic diagram of a sample testing device according to an exemplary embodiment of the present application;
FIG. 2 is a schematic diagram of a sample testing device shown in another exemplary embodiment of the present application;
FIG. 3 is a schematic view of a sample rack shown in an exemplary embodiment of the application;
FIG. 4 is a schematic diagram of a sample detection system with online relationship, according to an exemplary embodiment of the present application;
FIG. 5 is a flow chart of a sample detection method according to an exemplary embodiment of the present application;
FIG. 6 shows a schematic diagram of a computer system suitable for use in implementing an embodiment of the present application.
Detailed Description
Other advantages and effects of the present application will become apparent to those skilled in the art from the following disclosure, which describes the embodiments of the present application with reference to specific examples. The application may be practiced or carried out in other embodiments that depart from the specific details, and the details of the present description may be modified or varied from the spirit and scope of the present application. It should be noted that the following embodiments and features in the embodiments may be combined with each other without conflict.
It should be noted that the illustrations provided in the following embodiments merely illustrate the basic concept of the present application by way of illustration, and only the components related to the present application are shown in the drawings and are not drawn according to the number, shape and size of the components in actual implementation, and the form, number and proportion of the components in actual implementation may be arbitrarily changed, and the layout of the components may be more complicated.
In some instances, related operations of the present application have not been shown or described in the specification in order to avoid obscuring the core portions of the present application, and may be unnecessary to persons skilled in the art from a detailed description of the related operations, which may be presented in the description and general knowledge of one skilled in the art.
The numbering of the components itself, e.g. "first", "second", etc., is used herein merely to distinguish between the described objects and does not have any sequential or technical meaning. The term "coupled" as used herein includes both direct and indirect coupling (coupling), unless otherwise indicated.
Sample analysis generally refers to processing a sample such as blood, urine, etc., and detecting and analyzing the processed result by using some detection means (such as optical means), and obtaining an analysis result.
When the urine sample is analyzed, the urine sample can be detected by two different detection methods, namely dry chemistry and shaped, and the specific condition of the urine sample is comprehensively judged by the two detection methods. Specifically, the sample analyzer will draw a urine sample with a sample needle, transport the sample to a dry chemical detection module (typically a test strip), and simultaneously transport the sample to a patterned detection module for detection.
On the one hand, the patient can choose to perform independent dry chemical tests, and if the detection result is positive, the patient is usually required to perform a forming component test again; on the other hand, most patients in the hospital can choose to test in two modes simultaneously, if the results are all negative, the formation test is not needed to be seen, and the dry chemical test results of most patients in the hospital are positive products, namely all negative, if the two modes are selected to test simultaneously, the greater cost waste is generated in the test process. Based on this, the present application provides a sample detection system, a sample detection method, a sample detector, and a computer-readable storage medium, and these embodiments will be described in detail below.
The application provides a sample detection system, which comprises a sample detection device, and fig. 1 and 2 are schematic diagrams of the sample detection device according to an exemplary embodiment of the application. As shown in fig. 1 and 2, the sample detection device includes: a pre-storing area 110, a testing area 150, a recycling area 160, a sample transmission module 170, a sample sucking module 180, a second detection module 190 and a first detection module 1100;
a pre-storage area 110 for carrying a sample container for holding a sample to be tested.
In one embodiment, a sample rack 120 may be provided in the pre-stored area, with sample containers provided on the sample rack. Specifically, the sample rack 120 is provided with a plurality of sample container positions in sequence along its length direction, the sample container positions being for carrying sample containers, the sample containers being capable of carrying samples. In general, the sample holder carried by the pre-storage area 110 has sample containers carried by sample container positions that are filled with samples to be tested, where the samples to be tested may be referred to as first samples. Fig. 3 is a schematic view of a sample rack according to an exemplary embodiment of the present application, on which a plurality of sample container positions 1201 are provided, in which sample containers, which may be test tubes, can be more firmly placed. The sample container may be one or more cavities, the plurality of cavities being arranged in sequence. Of course, in other embodiments, a structure other than that shown in fig. 3 may be employed as a sample holder to carry the sample container, without any limitation. In the following embodiments, the sample container is described as being on a sample rack.
And the test area 150 is used for executing a sample sucking operation on the sample to be tested transmitted from the pre-storing area, and the sample sucking operation is performed by the sample sucking module 180. After receiving the control instruction of the controller, the sample transmission module 170 transmits the sample rack 120 in the pre-storage area 110 to the test area 150 from the pre-storage area 110 according to the first transmission direction, and the sample sucking module 180 is used for sucking samples to be tested in the sample container at the sample container position 1201 in the test area. In particular, the sample-sucking module may be a sample-sucking needle.
In one embodiment, the test area includes a sample sucking position, where the sample sucking position may be a fixed position in the test area, and the sample sucking module 190 corresponds to the sample sucking position. The controller controls the sample container to move from the pre-storing area 110 to the testing area 150 via the sample transmission module 170, and during this movement, the controller controls the sample container on the sample rack to stay on the sample sucking position in sequence, so that the sample sucking module is used for executing the sample sucking operation on the sample to be tested in the sample container on the sample sucking position. When the sample container is positioned on the sample sucking position, the sample sucking module extends downwards and stretches into the sample container, and then the sample to be detected in the sample container is subjected to sample sucking operation, so that the collection of the sample is completed.
And a recycling area 160 for receiving the sample racks transferred from the testing area. The sample in the sample container on the sample rack 120 in the recovery area 160 is the sample remaining after the sample sucking operation by the sample sucking module. The sample rack containing the remaining sample is in the recovery zone 160 until the sample suctioned by the sample suction module has completed the test. The sample rack in the recovery area is a sample rack to be recovered, and the sample contained in the sample container on the sample rack to be recovered is the sample to be recovered.
A controller for controlling the sample transmission module to carry out transmission control on the sample rack, wherein the transmission control comprises: the transfer of sample racks from the pre-store area 110 to the test area 150, the transfer of sample racks from the test area 150 to the recovery area 160, and the transfer of sample racks from the recovery area 160 to the pre-store area 110 or the transfer of sample racks from the recovery area 160 to the test area. It should be noted that, the transfer of the sample rack from the pre-storing area 110 to the testing area 150 and the transfer of the sample rack from the testing area 150 to the recycling area 160 are performed in a first direction, and the transfer of the sample rack from the recycling area 160 to the pre-storing area 110 or the transfer of the sample rack from the recycling area 160 to the testing area 150 is performed in a second direction, wherein the first direction and the second direction are opposite to each other. As shown in fig. 1, the sample transfer module includes a first transfer rail 171 through which the transfer of the sample rack from the pre-storage area 110 to the test area 150 and the transfer of the sample rack from the test area 150 to the recovery area 160 are performed; the transfer of the sample rack from the reclamation area 160 to the pre-storage area 110 may be performed through a second transfer track; the transport of the sample rack from the recovery zone 160 to the test zone 150 may be performed by a first transport track. The first and second transfer rails 171 and 172 are located on opposite sides of the sample detection device, respectively. During testing, the sample rack in the pre-storing area is pushed onto the first conveying track, then the sample sucking operation is carried out in the sample sucking area, the sample rack is continuously conveyed to the position of the recovery area after the sample sucking operation, and then the sample rack is pushed up to the recovery area from the first conveying track.
The first detection module 1100 is configured to respond to a first control instruction of the controller to perform sample detection on one or more samples to be detected sucked by the sample suction module 180 in a first detection manner, so as to obtain one or more first detection results, and if the one or more first detection results are normal detection results, the detection is ended; wherein, a plurality of samples to be tested for sample detection in a first detection mode are contained in sample containers on a sample rack transmitted from a pre-storing area to a testing area. It should be noted that the first detection mode may be a dry chemical test.
Taking the sample to be tested as urine as an example, after the sample sucking module 180 sucks the urine sample, the first detection module 1100 performs dry chemical detection on each urine sample to obtain a plurality of detection results, namely a first detection result. At this time, it is necessary to determine whether the plurality of detection results include an abnormal detection result, i.e., a positive detection result. If all the detection results are abnormal detection results, namely negative detection results, the next detection is not needed at the moment, and the detection flow is ended. If at least one positive detection result exists, the abnormal sample exists in the sucked urine sample, and further detection is needed to be carried out on the abnormal sample to obtain a more detailed detection result, namely, a forming component test is needed to be carried out.
The second detection module 190 is configured to respond to a second control instruction of the controller, and perform sample detection on the one or more abnormal samples sucked by the suction module in a second detection manner, so as to obtain one or more second detection results; the second control instruction is generated when at least one abnormal detection result is included in the plurality of first detection results, the abnormal sample is a sample corresponding to the abnormal detection result, and the abnormal sample is sucked from a sample container on a sample rack in the recovery area. The second detection module 190 performs the formation test based on the sample to be tested corresponding to the abnormal detection result as the detection result of the first detection module 1100, that is, when the first detection result is the abnormal detection result, the sample to be tested in the sample container corresponding to the abnormal detection result (the sample to be tested may be referred to as the second sample) is obtained at this time, and then the second sample is tested by the formation test method, so as to obtain the second detection result.
In one embodiment, the sample transfer module includes a first transfer rail 171 and a second transfer rail 172, the first transfer rail being used to transfer sample containers from the pre-storage area to the testing area in a first direction, to transfer sample containers from the testing area to the recycling area in a first direction, and to transfer sample containers from the recycling area to the testing area in a second direction; the second transmission track is used for transmitting the sample container from the recovery area to the pre-storage area in a second direction; wherein the first direction and the second direction are opposite directions to each other. Through the mode, the sample to be detected can be transmitted from the pre-storage area to the recovery area, after the abnormal sample appears, the abnormal sample is transmitted from the recovery area to the pre-storage area, so that the cyclic detection of the abnormal sample is realized, and the problem that the sample transmission is carried out only by a single transmission track and the reverse transmission cannot be carried out is avoided.
It should be noted that the first direction may be understood as a leftward direction in fig. 3, and the second direction may be understood as a rightward direction.
The sample container corresponding to the abnormal detection result can be transmitted from the recovery area 160 to the test area 110 through the first transmission track 171 of the sample transmission module 170 in the second direction, or can be transmitted from the recovery area 160 to the pre-storage area 110 through the second transmission track 172 of the sample transmission module 170 in the second direction, and then transmitted from the pre-storage area 110 to the test area 150 through the first transmission track 171 in the first direction, and the sample sucking operation is performed by the sample sucking module 180, and finally the detection of the tangible component is completed by the second detection module.
Referring to fig. 1, in fig. 1, the sample detection apparatus further includes:
the information detection module 140 is configured to detect a label of a sample container on the sample rack, obtain patient information corresponding to each sample container, and obtain first patient information. It should be noted that, the label detection of the sample container may collect the information on the label in a non-contact manner. Specifically, a label may be posted on the test tube, patient information written in the label, and then read by an RFID reader. In this embodiment, the patient information includes, but is not limited to, sex, age, item to be tested.
In one embodiment, the sample detection device further comprises:
the position detection module 130 is configured to detect whether a sample container exists on the sample rack and detect a position and a number of sample containers on the sample rack, so as to obtain first position information, where the first position information includes: the number of sample containers information and the position information of each sample container on the sample rack. It should be noted that there are various methods for detecting the position and number of sample containers (test tubes), including but not limited to: a method by image recognition, a method by RFID detection, a method of combining an image with RFID detection, and the like. For the method of RFID detection, an RFID tag (Radio Frequency Identification, RFID, radio frequency identification technology) may be provided on a test tube, and the number of the test tube may be recorded on the RFID tag, or may be location information; and then the RFID tag is identified through the RFID reader, so that the positions of the test tubes and the number of the test tubes on the test tube rack are obtained. For the image detection method, the image recognition unit can be used for collecting the image containing the test tube rack, then recognizing the image to obtain the number of test tubes, and recording the positions of the test tubes.
In an embodiment, the controller controls the position detection module to detect the sample container corresponding to the abnormality detection result to obtain second position information, and controls the information detection module to detect the label of the sample container corresponding to the abnormality detection result to obtain second patient information; the controller determines whether the sample container corresponding to the abnormality detection result is an abnormal sample container according to the first position information, the second position information, the first patient information, and the second patient information. When the first detection module detects the sample to be detected, the position of the sample to be detected and the corresponding information of the patient are recorded. When the detection result output by the first detection module contains an abnormal detection result, the position of the test tube corresponding to the abnormal detection result and the patient information can be recorded. In order to prevent errors when the second detection module performs component detection, the two sucked samples need to be compared to judge whether the samples are replaced or not so as to ensure the accuracy of the test. Specifically, the first position information is compared with the second position information, the first patient information is compared with the second patient information, and if the first position information is consistent with the second position information and the first patient information is consistent with the second patient information, the sample is judged not to be replaced.
In an embodiment, the sample detection system includes a plurality of the sample detection devices having an online relationship, where the online relationship indicates that when a first detection result output by one of the sample detection devices is an abnormal detection result, the abnormal sample is transmitted to the other sample detection devices, so that a second detection module of the sample detection device that receives the abnormal sample performs sample detection based on the abnormal sample. It should be noted that before the sample to be detected corresponding to the abnormal detection result is transmitted to the other sample detection devices, it is also required to determine whether the other sample detection devices have enough idle positions for detection, and determine whether the detection device is the last detection device of the plurality of detection devices having an online relationship, if the last detection device is the last detection device, the sample rack corresponding to the abnormal detection result cannot be transmitted to the other detection devices. Referring to fig. 4, fig. 4 is a schematic diagram of a sample detection system with online relationship according to an exemplary embodiment of the application. In fig. 4, a first sample detection device 410 and a second sample detection device 420 are included, where the first sample detection device determines whether the second sample detection device has the capability of performing the composition detection when the dry detection is performed on the sample provided by the patient a, that is, whether the second sample detection device has the capability of performing the composition detection, that is, whether the second sample detection device does not have enough gaps, the composition detection is still performed by the first sample detection device, and if the second sample detection device does not have enough gaps, the sample rack is transmitted to the second sample detection device through the second transmission track, and the composition detection on the patient a by the second sample detection device is performed by the second sample detection device.
When the sample detection system includes a plurality of sample detection devices, if the dry chemical detection result of one of the sample detection devices is an abnormal detection result, the capability of the other sample detection device for performing the component detection may be obtained first, and it may be determined which sample detection device has the strongest detection capability, that is, the remaining sample rack for performing the component detection has the largest detection space, and the sample rack to which the sample container corresponding to the abnormal detection result belongs may be transferred to the sample detection device having the strongest detection capability.
In the application, a sample frame in a pre-storing area is moved to a testing area through a sample transmission module, and samples in a sample container on the sample frame are sucked away through a sample sucking module at a designated position of the testing area to carry out a dry chemical test; after the sample sucking module sucks the sample, the sample frame is moved from the test area to the recovery area through the sample transporting module; after all the dry chemical tests of all the samples in the sample rack are completed, the controller analyzes whether the samples in the sample rack have abnormal detection samples, namely the result is positive, and if all the dry chemical results are negative, the controller informs the sample transport module that the sample rack is not moved, and the test is finished; if the dry chemical result is positive, the controller can inform the sample transportation module to move the sample frame from the recovery area to the test area, and the sample sucking module sucks samples again at the designated position of the test area, and then the forming component test is carried out. Therefore, when the dryness is positive, the method can avoid the positive patient from providing the sample to be tested again by re-transmitting the sample to be tested back to the test area for sample suction operation, thereby reducing the trouble of the positive patient, and simultaneously, ending the detection flow when the first detection result is negative, thereby saving the additional cost caused by the detection of the formed components.
Referring to fig. 5, fig. 5 is a flowchart of a sample detection method according to an exemplary embodiment of the present application, the sample detection method is applied to the sample detection system, and the sample detection method at least includes steps S510 to S570, which are described in detail as follows:
step S510, controlling the sample container to move from the pre-storing area to the testing area;
step S520, sequentially performing sample sucking operation on samples to be tested in one or more sample containers in a test area through a sample sucking module to obtain one or more first samples;
step S530, controlling the sample container to move from the test area to the recovery area;
step S540, performing sample detection on the one or more first samples in a first detection manner, to obtain one or more first detection results;
step S550, judging whether the first detection result includes an abnormal detection result, if one or more first detection results are all normal detection results, ending the detection; if the one or more first detection results comprise at least one abnormal detection result, moving the sample container in the recovery area to the test area or moving the sample container in the recovery area to the pre-stored area and then moving the sample container in the recovery area to the test area through the pre-stored area;
step S560, sequentially sucking abnormal samples from the sample containers corresponding to the abnormal detection results in the test area through the sample sucking module to obtain one or more second samples;
in step S570, sample detection is performed on the one or more second samples in a second detection manner, so as to obtain one or more first detection results.
It should be noted that, the sample detection method provided by the above embodiment and the sample detection system provided by the above embodiment belong to the same concept, and the specific implementation manner of each step has been described in detail in the system embodiment, which is not repeated here.
The present application also provides a sample detector comprising:
one or more processors;
and a storage means for storing one or more programs which, when executed by the one or more processors, cause the electronic device to implement the steps of the sample detection method.
The present application also provides a computer-readable storage medium, characterized in that a computer program is stored thereon, which, when being executed by a processor of a computer, causes the computer to perform the steps of the sample detection method.
FIG. 6 shows a schematic diagram of a computer system suitable for use in implementing an embodiment of the application. It should be noted that, the computer system of the electronic device shown in fig. 6 is only an example, and should not impose any limitation on the functions and the application scope of the embodiments of the present application.
As shown in fig. 6, the computer system includes a central processing unit (Central Processing Unit, CPU) that can perform various appropriate actions and processes, such as performing the methods described in the above embodiments, according to a program stored in a Read-Only Memory (ROM) or a program loaded from a storage section into a random access Memory (Random Access Memory, RAM). In the RAM, various programs and data required for the system operation are also stored. The CPU, ROM and RAM are connected to each other by a bus. An Input/Output (I/O) interface is also connected to the bus.
The following components are connected to the I/O interface: an input section including a keyboard, a mouse, etc.; an output section including a Cathode Ray Tube (CRT), a liquid crystal display (Liquid Crystal Display, LCD), and the like, and a speaker, and the like; a storage section including a hard disk or the like; and a communication section including a network interface card such as a LAN (Local Area Network ) card, a modem, or the like. The communication section performs communication processing via a network such as the internet. The drives are also connected to the I/O interfaces as needed. Removable media such as magnetic disks, optical disks, magneto-optical disks, semiconductor memories, and the like are mounted on the drive as needed so that a computer program read therefrom is mounted into the storage section as needed.
In particular, according to embodiments of the present application, the processes described above with reference to flowcharts may be implemented as computer software programs. For example, embodiments of the present application include a computer program product comprising a computer program embodied on a computer readable medium, the computer program comprising a computer program for performing the sample detection method shown in flowchart 3. In such embodiments, the computer program may be downloaded and installed from a network via a communication portion, and/or installed from a removable medium. When being executed by a Central Processing Unit (CPU), performs the various functions defined in the system of the present application.
It should be noted that, the computer readable medium shown in the embodiments of the present application may be a computer readable signal medium or a computer readable storage medium, or any combination of the two. The computer readable storage medium may be, for example, an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any combination thereof. More specific examples of the computer-readable storage medium may include, but are not limited to: an electrical connection having one or more wires, a portable computer diskette, a hard disk, a Random Access Memory (RAM), a read-Only Memory (ROM), an erasable programmable read-Only Memory (Erasable Programmable Read Only Memory, EPROM), flash Memory, an optical fiber, a portable compact disc read-Only Memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing. In the present application, a computer-readable signal medium may comprise a data signal propagated in baseband or as part of a carrier wave, with a computer-readable computer program embodied therein. Such a propagated data signal may take any of a variety of forms, including, but not limited to, electro-magnetic, optical, or any suitable combination of the foregoing. A computer readable signal medium may also be any computer readable medium that is not a computer readable storage medium and that can communicate, propagate, or transport a program for use by or in connection with an instruction execution system, apparatus, or device. A computer program embodied on a computer readable medium may be transmitted using any appropriate medium, including but not limited to: wireless, wired, etc., or any suitable combination of the foregoing.
The flowcharts and block diagrams in the figures illustrate the architecture, functionality, and operation of possible implementations of systems, methods and computer program products according to various embodiments of the present application. Where each block in the flowchart or block diagrams may represent a module, segment, or portion of code, which comprises one or more executable instructions for implementing the specified logical function(s). It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown in succession may, in fact, be executed substantially concurrently, or the blocks may sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams or flowchart illustration, and combinations of blocks in the block diagrams or flowchart illustration, can be implemented by special purpose hardware-based systems which perform the specified functions or acts, or combinations of special purpose hardware and computer instructions.
The units involved in the embodiments of the present application may be implemented by software, or may be implemented by hardware, and the described units may also be provided in a processor. Wherein the names of the units do not constitute a limitation of the units themselves in some cases.
Another aspect of the application also provides a computer readable storage medium having stored thereon a computer program which, when executed by a processor of a computer, causes the computer to perform a sample detection method as described above. The computer-readable storage medium may be included in the electronic device described in the above embodiment or may exist alone without being incorporated in the electronic device.
The above embodiments are merely illustrative of the principles of the present application and its effectiveness, and are not intended to limit the application. Modifications and variations may be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the application. It is therefore intended that all equivalent modifications and changes made by those skilled in the art without departing from the spirit and technical spirit of the present application shall be covered by the appended claims.

Claims (11)

1. A sample detection system, the sample detection system comprising a sample detection device, the sample detection device comprising:
the pre-storing area is used for carrying a sample container, and the sample container is used for containing a sample to be tested;
the test area is used for executing sample sucking operation on the sample to be detected in the sample container transmitted from the pre-storing area, and the sample sucking operation is performed through a sample sucking module;
a recovery zone for receiving the sample containers transferred from the test zone;
a controller for controlling the sample transfer module to perform transfer control on the sample container, the transfer control comprising:
transferring the sample container from the pre-storage area to the test area, transferring the sample container from the test area to the recovery area, and transferring the sample container from the recovery area to the pre-storage area or transferring the sample container from the recovery area to the test area;
the first detection module is used for responding to a first control instruction of the controller to detect one or more samples to be detected sucked by the sample sucking module in a first detection mode to obtain one or more first detection results, and if the one or more first detection results are normal detection results, the detection is finished; the sample container is used for storing a plurality of samples to be detected, wherein the samples to be detected are detected in a first detection mode, and the samples to be detected are transmitted to the test area from the pre-storage area;
the second detection module is used for responding to a second control instruction of the controller to detect one or more abnormal samples sucked by the sample suction module in a second detection mode to obtain one or more second detection results; the second control instruction is generated when at least one abnormal detection result is included in the plurality of first detection results, the abnormal sample is a sample corresponding to the abnormal detection result, and the abnormal sample is sucked from a sample container located in the recovery area.
2. The sample detection system of claim 1, wherein the sample detection device further comprises:
and the information detection module is used for detecting the labels on the sample containers to obtain patient information corresponding to each sample container and obtain first patient information.
3. The sample detection system of claim 1, wherein the sample detection device further comprises:
the position detection module is used for detecting whether a sample container exists or not, detecting the position and the number of the sample containers, and obtaining first position information, wherein the first position information comprises the number information of the sample containers and the position information of each sample container.
4. The sample detection system according to claim 3, wherein the controller controls the position detection module to detect the sample container corresponding to the abnormality detection result to obtain second position information, and controls the information detection module to detect the label of the sample container corresponding to the abnormality detection result to obtain second patient information; the controller determines whether the sample container corresponding to the abnormality detection result is an abnormal sample container according to the first position information, the second position information, the first patient information, and the second patient information.
5. The sample detection system of claim 1, wherein the first detection mode is a dry chemistry test and the second detection mode is a formed component test.
6. The sample detection system according to claim 1, wherein the test area includes a sample sucking position, and the controller controls the sample container to move from the pre-storing area to the test area and controls the sample container to stay on the sample sucking position in sequence, so that the sample sucking module is used for executing a sample sucking operation on a sample to be detected in the sample container on the sample sucking position.
7. The sample detection system of claim 1, comprising a plurality of the sample detection devices having an online relationship that indicates that when a first detection result output by one of the sample detection devices is an abnormal detection result, the abnormal sample is transmitted to the other sample detection devices, so that a second detection module of the sample detection device that receives the abnormal sample performs sample detection based on the abnormal sample.
8. The sample detection system of claim 1, wherein the sample transfer module comprises a first transfer track and a second transfer track,
the first transmission track is used for transmitting the sample container from the pre-storing area to the testing area in a first direction, transmitting the sample container from the testing area to the recycling area in the first direction and transmitting the sample container from the recycling area to the testing area in a second direction;
the second transmission track is used for transmitting the sample container from the recovery area to the pre-storage area in a second direction;
wherein the first direction and the second direction are opposite directions to each other.
9. A sample detection method, characterized in that it is applied to the sample detection system according to any one of claims 1 to 8, comprising:
controlling the sample container to move from the pre-storing area to the testing area;
sequentially carrying out sample sucking operation on samples to be tested in one or more sample containers in a test area through a sample sucking module to obtain one or more first samples;
controlling the sample container to move from the test zone to the recovery zone;
sample detection is carried out on the one or more first samples in a first detection mode, so that one or more first detection results are obtained;
judging whether the first detection result contains an abnormal detection result or not, and if one or more first detection results are all normal detection results, ending the detection; if the one or more first detection results comprise at least one abnormal detection result, moving the sample container in the recovery area to the test area or moving the sample container in the recovery area to the pre-stored area and then moving the sample container in the recovery area to the test area through the pre-stored area;
sequentially sucking abnormal samples from sample containers corresponding to abnormal detection results through a sample sucking module in a test area to obtain one or more second samples;
and carrying out sample detection on the one or more second samples in a second detection mode to obtain one or more first detection results.
10. A sample detector, the sample detector comprising:
one or more processors;
storage means for storing one or more programs that, when executed by the one or more processors, cause the electronic device to implement the steps of the sample detection method of claim 9.
11. A computer-readable storage medium, having stored thereon a computer program which, when executed by a processor of a computer, causes the computer to perform the steps of the sample detection method according to claim 9.
CN202310485235.3A 2023-04-28 2023-04-28 Sample detection method, system, detector and medium Pending CN116679074A (en)

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