CN116350553A - 一种草本防秃精华及其制备方法 - Google Patents
一种草本防秃精华及其制备方法 Download PDFInfo
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- CN116350553A CN116350553A CN202310052278.2A CN202310052278A CN116350553A CN 116350553 A CN116350553 A CN 116350553A CN 202310052278 A CN202310052278 A CN 202310052278A CN 116350553 A CN116350553 A CN 116350553A
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- Cosmetics (AREA)
Abstract
本发明提出了一种草本防秃精华,以质量分数计,包括0.27‑11.10%植物提取物,0.26‑6.10%营养元素以及1.51‑21.00%保湿剂,余量为水;所述植物提取物包括齿瓣延胡索根提取物、红花提取物、川党参根提取物、当归提取物、川芎根提取物、乳香提取物、没药提取物、甘草提取物、马鞭草提取物、薰衣草油。本发明通过利用天然草本植物提取物为主要功效原料结合生物技术,多学科交叉研究制备而成,对头皮作用温和、刺激性小、安全性高;通过草本中药提取物及复合维生素B、水解胶原、生物多肽等多种营养素的相互协同作用,促进头部肌肤血液循环,补充头皮营养,改善头皮微环境,令头皮保持良好生长状态,从而有效预防脱发。
Description
技术领域
本发明涉及一种草本防秃精华及其制备方法。
背景技术
一直以来,头发都在人的仪容仪表中起着重要的作用,同时从中医的角度讲,头发也是人体健康状况的重要指标。头发是从头皮下毛囊长出来的,头发的生长具有周期性,即可分为生长期、退行期及休止期,处于生长期的毛发约占全部毛发的85%,此期间头发每天增长0.27~0.4mm。毛发的生长期为2~6年,进入退行期以后,毛囊下部包括生发部分的毛球开始萎缩。毛发不再增长且变得松动易于脱落;处于退行期的毛发约占1%;休止期时,毛囊下部完全萎缩,毛发脱落,处于休止期的毛发约占14%;休止期持续3~6个月,而后毛囊受进入生长期,又有新发长出。近年来,随着生活节奏加快,人们生活压力大,经常加班、熬夜,生活不规律,造成健康问题,影响头发质量,常常造成发质差、干燥、易脱落等问题。脱发患者逐年增多且趋于年轻化,在20~40岁的男性群体中,患有脱发问题的比例高达40%以上。
脱发的根本原因是头皮生态破坏、毛孔堵塞、毛囊的萎缩与退化,由于油脂分泌过旺、毛发毛孔堵塞等原因导致毛囊里细胞萎缩甚至坏死,使其无法吸收周围头发养分,毛发不再生长。在正常的情况下,毛囊里的毛***有丰富的毛细血管,它能从血液中吸收头发生长所必需的养分,保障头发正常生长。头发由于新陈代谢,每天脱落50-100根左右,但不影响头发的整体数量。但由于皮脂腺分泌过旺、毛孔堵塞等原因,头发正常生长的环境会遭到破坏,使头发不能正常的生长,就会出现脱发、断发等现象。
目前,市场上治疗脱发生发的药物多而乱,由于对脱发的原因研究不透,造成现有的止脱生发药物不能标本兼治,不仅价格高,而且对头皮刺激性大,效果不理想,有些产品还有副作用。如何获得一种防脱发的天然温和产品,是当前所属领域急需解决的技术难题。
发明内容
本发明要解决的技术问题是克服现有技术存在的缺陷,本发明提出了一种草本防秃精华及其制备方法,提供一种安全有效、效果稳定的防脱发产品。
为解决上述技术问题,本发明采用的技术方案是:一种草本防秃精华,以质量分数计,包括0.27-11.10%植物提取物,0.26-6.10%营养元素以及1.51-21.00%保湿剂,余量为水;
所述植物提取物包括齿瓣延胡索根提取物、红花提取物、川党参根提取物、当归提取物、川芎根提取物、乳香提取物、没药提取物、甘草提取物、马鞭草提取物、薰衣草油。
进一步地,所述植物提取物以质量分数计,包括0.1-2%齿瓣延胡索根提取物,0.1-2%红花提取物,0.01-1%川党参根提取物,0.01-1%当归提取物,0.01-1%川芎根提取物,0.01-1%乳香提取物,0.01-1%没药提取物,0.01-1%甘草提取物,0.01-1%马鞭草提取物以及0.001-0.1%薰衣草油。
进一步地,所述营养元素以质量分数计,包括0.1-2%透明质酸钠,0.05-1%维生素E,0.1-2%棕榈酰五肽-4,0.01-1%甘露聚糖以及0.001-0.1%复合维生素B。
进一步地,所述复合维生素B包括生物素、叶酸、维生素B12、维生素B3、泛酸、维生素B6、维生素B2、维生素B1以及酵母多肽。
进一步地,所述保湿剂以质量分数计,包括1-10%丁二醇,0.1-2%聚谷氨酸,0.1-2%水解小核菌,0.01-1%水解胶原,0.1-2%抗坏血酸,0.1-2%甘油以及0.1-2%三乙醇胺。
进一步地,还包括质量分数为0.1-2%的增稠剂,所述增稠剂为卡波姆。
进一步地,还包括质量分数为0.1-2%的防腐剂,所述防腐剂为对羟基苯乙酮。
进一步地,一种草本防秃精华的制备方法,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的A相原料倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;所述A相原料包括卡波姆;
S2、逐步降温,依次倒入称量好的B相原料、C相原料及余量纯化水后搅拌均匀;
所述B相原料包括丁二醇、透明质酸钠、对羟基苯乙酮、聚谷氨酸、水解小核菌胶以及维生素E;
所述C相原料包括齿瓣延胡索根提取物、红花提取物、川党参根提取物、当归提取物、川芎根提取物、乳香提取物、没药提取物、甘草提取物、马鞭草提取物;
S3、进一步降温并依次倒入称量好的D相原料及E相原料搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品;
所述D相包括水解胶原、棕榈酰五肽-4、抗坏血酸、甘油、甘露聚糖、复合维生素B;
所述E相包括三乙醇胺以及薰衣草油。
与现有技术相比,本发明的有益效果包括:通过利用草本植物提取物为主要功效原料结合生物技术,多学科交叉研究制备而成,对头皮作用温和、刺激性小、安全性高;通过植物提取物及复合维生素B、水解胶原、生物多肽等多种营养素的相互协同作用,促进头部肌肤血液循环,补充头皮营养,改善头皮微环境,令头皮保持良好生长状态,从而有效预防脱发。
具体实施方式
容易理解,根据本发明的技术方案,在不变更本发明实质精神下,本领域的一般技术人员可以提出可相互替换的多种结构方式以及实现方式。因此,以下具体实施方式仅是对本发明的技术方案的示例性说明,而不应当视为本发明的全部或者视为对本发明技术方案的限定或限制。
一种草本防秃精华,由纯化水及A相、B相、C相、D相、E相构成,各项所含的组成成分及其重量占比分别为:
本发明的原理:
当归提取物:能扩张皮肤毛细血管,加快血液循环,具有促进头发生长、滋养头发的功效;能够活血补血,可以改善气血不足引起的头发脱落、颜色暗黄等情况;丰富的微量元素,能营养皮肤,防止粗糙。
乳香提取物的功效作用:具有显著的抗炎和活血化瘀作用;
没药提取物的功效作用:具有活血化瘀、抗炎镇痛、抗菌、消肿生肌等作用;
红花提取物的功效作用:具有抗炎、活血通经、祛瘀止痛的功效;
齿瓣延胡索根提取物:具有活血散瘀,行气止痛作用,也有镇静的作用。
川芎根提取物:具有活血行气,祛风止痛的功效。
川党参根提取物:含有甾醇、党参苷和生物碱等组分,可补中益气,健脾益肺,适用于气血两亏的病症,可达到调理皮肤的效果。
甘草提取物的功效作用:具有补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药的功效。
马鞭草提取物:具有消炎止痛、止血、抗菌等功效。
薰衣草油:具有杀菌、消炎作用。
本发明当归提取物在配方中为君药,发挥主要治疗作用,能扩张皮肤毛细血管,加快血液循环,具有促进头发生长、滋养头发的功效;乳香提取物、没药提取物、红花提取物、齿瓣延胡索根提取物和川芎根提取物在配方中为臣药,协助君药发挥作用;川党参根提取物在配方中为佐药,用于辅助君臣药治疗主症并且治疗兼症;甘草提取物、马鞭草提取物和薰衣草油在配方中为使药,消炎、杀菌,改善头皮生生态,引导药物发挥最大效能。
通过本发明使各原料的有机结合,配方合理,很好地发挥了协同增效作用,通过促进头皮血液循环,抑菌抗炎,同时多种营养物质及保湿成分渗入肌肤组织,改善头部肌肤环境生态,补充头皮营养,令头皮保持良好生长状态,从而起到预防脱发的效果。
其制备方法包括以下步骤:
S1、按配方称量各项所需的原料;
S2、向配制罐中加入所需纯化水量,将称量好的A相原料倒入配制罐中,盖上配制罐盖,搅拌均匀,将配制溶液升温到70℃以上,保温30分钟;
S3、逐步降温,依次倒入称量好的B相原料、C相原料,盖上配制罐盖,搅拌均匀;倒入所需剩余纯化水,搅拌均匀;
S4、再降温,倒入称量好的D相原料,搅拌均匀,倒入称量好的E相原料,盖上配制罐盖,搅拌均匀;
S5、包装封口,即得具有防脱发功效的草本防秃精华成品。
以下结合实施例对于本申请的技术效果作进一步的说明。
实施例1
一种草本防秃精华的制备方法,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的0.1%卡波姆倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;
S2、逐步降温,依次倒入称量好的1%丁二醇、0.1%透明质酸钠、0.1%对羟基苯乙酮、0.1%聚谷氨酸、0.1%水解小核菌胶以及0.05%维生素E,0.1%齿瓣延胡索根提取物、0.1%红花提取物、0.01%川党参根提取物、0.01%当归提取物、0.01%川芎根提取物、0.01%乳香提取物、0.01%没药提取物、0.01%甘草提取物、0.01%马鞭草提取物及余量纯化水后搅拌均匀;
S3、进一步降温并依次倒入称量好的0.01%水解胶原、0.1%棕榈酰五肽-4、0.1%抗坏血酸、0.1%甘油、0.1%甘露聚糖、0.00%复合维生素B,0.1%三乙醇胺以及0.00%薰衣草油搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品。
实施例2
一种草本防秃精华的制备方法,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的0.56%卡波姆倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;
S2、逐步降温,依次倒入称量好的3.84%丁二醇、0.46%透明质酸钠、0.49%对羟基苯乙酮、0.67%聚谷氨酸、0.72%水解小核菌胶以及0.34%维生素E,0.66%齿瓣延胡索根提取物、0.62%红花提取物、0.35%川党参根提取物、0.51%当归提取物、0.15%川芎根提取物、0.22%乳香提取物、0.31%没药提取物、0.15%甘草提取物、0.27%马鞭草提取物及余量纯化水后搅拌均匀;
S3、进一步降温并依次倒入称量好的0.36%水解胶原、0.69%棕榈酰五肽-4、0.78%抗坏血酸、0.62%甘油、0.27%甘露聚糖、0.03%复合维生素B,0.67%三乙醇胺以及0.02%薰衣草油搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品。
实施例3
一种草本防秃精华的制备方法,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的1.05%卡波姆倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;
S2、逐步降温,依次倒入称量好的5.5%丁二醇、1.05%透明质酸钠、1.05%对羟基苯乙酮、1.05%聚谷氨酸、1.05%水解小核菌胶以及0.52%维生素E,1.05%齿瓣延胡索根提取物、1.05%红花提取物、0.51%川党参根提取物、0.52%当归提取物、0.48%川芎根提取物、0.46%乳香提取物、0.53%没药提取物、0.52%甘草提取物、0.47%马鞭草提取物及余量纯化水后搅拌均匀;
S3、进一步降温并依次倒入称量好的0.54%水解胶原、1.05%棕榈酰五肽-4、1.05%抗坏血酸、1.05%甘油、0.45%甘露聚糖、0.05%复合维生素B,1.05%三乙醇胺以及0.05%薰衣草油搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品。
实施例4
一种草本防秃精华的制备方法,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的1.52%卡波姆倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;
S2、逐步降温,依次倒入称量好的7.68%丁二醇、1.62%透明质酸钠、1.84%对羟基苯乙酮、1.79%聚谷氨酸、1.23%水解小核菌胶以及0.76%维生素E,1.36%齿瓣延胡索根提取物、1.46%红花提取物、0.67%川党参根提取物、0.89%当归提取物、0.92%川芎根提取物、0.67%乳香提取物、0.59%没药提取物、0.66%甘草提取物、0.67%马鞭草提取物及余量纯化水后搅拌均匀;
S3、进一步降温并依次倒入称量好的0.75%水解胶原、1.44%棕榈酰五肽-4、1.26%抗坏血酸、1.85%甘油、0.51%甘露聚糖、0.08%复合维生素B,1.37%三乙醇胺以及0.09%薰衣草油搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品。
实施例5
一种草本防秃精华的制备方法,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的2%卡波姆倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;
S2、逐步降温,依次倒入称量好的10%丁二醇、2%透明质酸钠、2%对羟基苯乙酮、2%聚谷氨酸、2%水解小核菌胶以及1%维生素E,2%齿瓣延胡索根提取物、2%红花提取物、1%川党参根提取物、1%当归提取物、1%川芎根提取物、1%乳香提取物、1%没药提取物、1%甘草提取物、1%马鞭草提取物及余量纯化水后搅拌均匀;
S3、进一步降温并依次倒入称量好的1%水解胶原、2%棕榈酰五肽-4、2%抗坏血酸、2%甘油、1%甘露聚糖、0.1%复合维生素B,2%三乙醇胺以及0.1%薰衣草油搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品。
产品安全性
(1)本发明产品委托第三方检测机构根据《化妆品安全技术规范》(2015年版)进行安全性检验,结果如下:
①微生物检验:菌落总数,霉菌和酵母菌总数,耐热大肠菌群,金黄色葡萄球菌,铜绿假单胞菌符合《化妆品安全技术规范》(2015年版)对微生物指标的要求。
②理化检验:汞,铅,砷,镉,二噁烷的检验结果符合《化妆品安全技术规范》(2015年版)的要求。
③毒理学试验:
a.多次皮肤刺激性试验结果:无刺激性。
b.皮肤***反应试验结果:未见皮肤***反应。
c.皮肤光毒性试验结果:未见皮肤光毒性。
d.细菌回复突变试验结果:加S9和未加S9的条件下,受试物均未见致突变性。
e.体外哺乳动物细胞染色体畸变试验结果:阴性。
(2)本发明产品委托第三方检测机构根据《化妆品安全技术规范》(2015年版)进行人体试用试验,结果如下:共有30名受试者完成了测试,参考2015年版《化妆品安全技术规范》中规定的人体安全性试验皮肤不良反应分级标准,30人中0例出现皮肤不良反应。
由以上测试结果可知,产品安全性各项指标均合格,对人体安全无刺激。
产品有效性
本发明产品委托第三方检测机构对防脱发功效进行了测试,通过60例受试者持续使用本发明产品12周,对脱发计数和毛发密度进行计数评估,检测产品使用前、使用4周、8周、12周受试部位的变化。
检测结果显示:
①试用试验产品后,试验产品组的脱发计数改善程度在各回访时间点均显著优于阴性对照组(p<0.05);
②试用试验产品后,试验产品组的局部毛发密度改善程度在各回访时间点与阴性对照组相比均无显著性差异(p≥0.05);
③试用试验产品后,试验产品组的整体毛发密度改善程度在使用后12周回访时显著优于阴性对照组(p<0.05);
综上所述,在本试验条件下,试验产品具有防脱功效。
本发明的技术范围不仅仅局限于上述说明中的内容,本领域技术人员可以在不脱离本发明技术思想的前提下,对上述实施例进行多种变形和修改,而这些变形和修改均应当属于本发明的保护范围内。
Claims (8)
1.一种草本防秃精华,其特征在于,以质量分数计,包括0.27-11.10%植物提取物,0.26-6.10%营养元素以及1.51-21.00%保湿剂,余量为水;
所述植物提取物包括齿瓣延胡索根提取物、红花提取物、川党参根提取物、当归提取物、川芎根提取物、乳香提取物、没药提取物、甘草提取物、马鞭草提取物、薰衣草油。
2.根据权利要求1所述的草本防秃精华,其特征在于,所述植物提取物以质量分数计,包括0.1-2%齿瓣延胡索根提取物,0.1-2%红花提取物,0.01-1%川党参根提取物,0.01-1%当归提取物,0.01-1%川芎根提取物,0.01-1%乳香提取物,0.01-1%没药提取物,0.01-1%甘草提取物,0.01-1%马鞭草提取物以及0.001-0.1%薰衣草油。
3.根据权利要求1所述的草本防秃精华,其特征在于,所述营养元素以质量分数计,包括0.1-2%透明质酸钠,0.05-1%维生素E,0.1-2%棕榈酰五肽-4,0.01-1%甘露聚糖以及0.001-0.1%复合维生素B。
4.根据权利要求3所述的草本防秃精华,其特征在于,所述复合维生素B包括生物素、叶酸、维生素B12、维生素B3、泛酸、维生素B6、维生素B2、维生素B1以及酵母多肽。
5.根据权利要求1所述的草本防秃精华,其特征在于,所述保湿剂以质量分数计,包括1-10%丁二醇,0.1-2%聚谷氨酸,0.1-2%水解小核菌,0.01-1%水解胶原,0.1-2%抗坏血酸,0.1-2%甘油以及0.1-2%三乙醇胺。
6.根据权利要求1所述的草本防秃精华,其特征在于,还包括质量分数为0.1-2%的增稠剂,所述增稠剂为卡波姆。
7.根据权利要求1所述的草本防秃精华,其特征在于,还包括质量分数为0.1-2%的防腐剂,所述防腐剂为对羟基苯乙酮。
8.一种草本防秃精华的制备方法,其特征在于,包括如下步骤:
S1、向配制罐中加入所需纯化水量,将称量好的A相原料倒入配制罐中并搅拌均匀,将所得配制溶液升温至70℃以上,保温30min;所述A相原料包括卡波姆;
S2、逐步降温,依次倒入称量好的B相原料、C相原料及余量纯化水后搅拌均匀;
所述B相原料包括丁二醇、透明质酸钠、对羟基苯乙酮、聚谷氨酸、水解小核菌胶以及维生素E;
所述C相原料包括齿瓣延胡索根提取物、红花提取物、川党参根提取物、当归提取物、川芎根提取物、乳香提取物、没药提取物、甘草提取物、马鞭草提取物;
S3、进一步降温并依次倒入称量好的D相原料及E相原料搅拌均匀后,包装封口即得具有防脱发功效的草本防秃精华成品;
所述D相包括水解胶原、棕榈酰五肽-4、抗坏血酸、甘油、甘露聚糖、复合维生素B;
所述E相包括三乙醇胺以及薰衣草油。
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