CN116270739A - 细胞结构体在制造溶酶体贮积病处置剂中的用途 - Google Patents

细胞结构体在制造溶酶体贮积病处置剂中的用途 Download PDF

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Publication number
CN116270739A
CN116270739A CN202310055866.1A CN202310055866A CN116270739A CN 116270739 A CN116270739 A CN 116270739A CN 202310055866 A CN202310055866 A CN 202310055866A CN 116270739 A CN116270739 A CN 116270739A
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China
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cells
biocompatible polymer
cell
polymer block
amino acid
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CN202310055866.1A
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English (en)
Chinese (zh)
Inventor
中村健太郎
北桥宗
半户里江
五条理志
上大介
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Fujifilm Corp
Kyoto Prefectural PUC
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Fujifilm Corp
Kyoto Prefectural PUC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/56—Porous materials, e.g. foams or sponges
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
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    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

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  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Gastroenterology & Hepatology (AREA)
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  • Dispersion Chemistry (AREA)
  • Rheumatology (AREA)
  • Composite Materials (AREA)
CN202310055866.1A 2017-06-30 2018-06-29 细胞结构体在制造溶酶体贮积病处置剂中的用途 Pending CN116270739A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2017128893 2017-06-30
JP2017-128893 2017-06-30
PCT/JP2018/024879 WO2019004446A1 (ja) 2017-06-30 2018-06-29 ライソゾーム病処置剤
CN201880044009.9A CN110913920A (zh) 2017-06-30 2018-06-29 溶酶体贮积病处置剂

Related Parent Applications (1)

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CN201880044009.9A Division CN110913920A (zh) 2017-06-30 2018-06-29 溶酶体贮积病处置剂

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CN116270739A true CN116270739A (zh) 2023-06-23

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CN201880044009.9A Pending CN110913920A (zh) 2017-06-30 2018-06-29 溶酶体贮积病处置剂
CN202310055866.1A Pending CN116270739A (zh) 2017-06-30 2018-06-29 细胞结构体在制造溶酶体贮积病处置剂中的用途

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CN201880044009.9A Pending CN110913920A (zh) 2017-06-30 2018-06-29 溶酶体贮积病处置剂

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US (1) US11999804B2 (ja)
EP (1) EP3646899A4 (ja)
JP (1) JP6903295B2 (ja)
CN (2) CN110913920A (ja)
WO (1) WO2019004446A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6964313B2 (ja) * 2017-03-17 2021-11-10 富士フイルム株式会社 細胞構造体の製造方法

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
AU4424497A (en) 1996-09-13 1998-04-02 Transkaryotic Therapies, Inc. Therapy for alpha-galactosidase a deficiency
EP1014176B1 (en) 1998-12-23 2009-04-29 FUJIFILM Manufacturing Europe B.V. Silver halide emulsions containing recombinant gelatin-like proteins
US7927587B2 (en) * 1999-08-05 2011-04-19 Regents Of The University Of Minnesota MAPC administration for the treatment of lysosomal storage disorders
US6992172B1 (en) 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
US20040033217A1 (en) * 2002-05-31 2004-02-19 Padmavathy Vanguri Intraperitoneal delivery of genetically engineered mesenchymal stem cells
EP1845107B1 (en) 2003-03-28 2019-05-29 FUJIFILM Manufacturing Europe B.V. Drug delivery system comprising RGD-enriched gelatine-like proteins with enhanced cell binding
KR20060123702A (ko) * 2003-08-21 2006-12-04 큐 세라퓨틱스, 아이엔씨. 리소좀성 축적병에서 결핍된 리소좀 효소전구체의 지속된분비를 위한 유전자 변형 체세포
AU2004296848A1 (en) 2003-12-04 2005-06-23 Regents Of The University Of Minnesota Compositions and methods for the treatment of lysosomal storage disorders
WO2008103043A1 (en) 2007-02-21 2008-08-28 Fujifilm Manufacturing Europe B.V. Rgd containing recombinant gelatin
EP2011495A1 (en) 2007-07-03 2009-01-07 Sygnis Bioscience GmbH & Co. KG Use of piperine and derivatives thereof for the therapy of neurological conditions
KR101744040B1 (ko) * 2010-03-01 2017-06-07 후지필름 가부시키가이샤 생체 친화성을 갖는 고분자 블록과 세포로 이루어지는 세포 구조체
JP5876787B2 (ja) * 2011-08-31 2016-03-02 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
JP5990298B2 (ja) * 2011-08-31 2016-09-14 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
CA2900897A1 (en) * 2013-02-12 2014-08-21 Reneuron Limited Method of producing microparticles
JP6330039B2 (ja) 2014-06-10 2018-05-23 富士フイルム株式会社 細胞構造体及び細胞構造体の製造方法
JP6330042B2 (ja) 2014-06-16 2018-05-23 富士フイルム株式会社 脳損傷治療用細胞構造体、その製造方法、及び脳損傷治療剤
JP6466464B2 (ja) * 2014-09-30 2019-02-06 富士フイルム株式会社 組成物、細胞構造体、膵島移植キット、膵島細胞移植治療剤及び血糖低下剤、膵島を含む組成物、膵島を含むキット、並びに膵島移植治療剤及び血糖低下剤

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EP3646899A4 (en) 2020-07-08
JP6903295B2 (ja) 2021-07-14
US11999804B2 (en) 2024-06-04
TW201906618A (zh) 2019-02-16
JPWO2019004446A1 (ja) 2020-05-21
EP3646899A1 (en) 2020-05-06
WO2019004446A1 (ja) 2019-01-03
CN110913920A (zh) 2020-03-24
US20200199178A1 (en) 2020-06-25

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