CN115989321A - 病毒制剂、用于配制病毒制剂的溶液及其用途 - Google Patents

病毒制剂、用于配制病毒制剂的溶液及其用途 Download PDF

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Publication number
CN115989321A
CN115989321A CN202280005157.6A CN202280005157A CN115989321A CN 115989321 A CN115989321 A CN 115989321A CN 202280005157 A CN202280005157 A CN 202280005157A CN 115989321 A CN115989321 A CN 115989321A
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virus
cancer
viral
solution
viral formulation
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吴可行
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Shanghai Xingshen Biotechnology Co ltd
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Shanghai Xingshen Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/766Rhabdovirus, e.g. vesicular stomatitis virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
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  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Medicinal Chemistry (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Veterinary Medicine (AREA)
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  • Biochemistry (AREA)
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Abstract

提供一种病毒制剂、用于配制病毒制剂的溶液及其用途。其中,病毒制剂含有:病毒;蔗糖;氯化镁。其中,所述病毒制剂含有Tris‑HCl缓冲液,并且pH为7.2~7.6。

Description

PCT国内申请,说明书已公开。

Claims (18)

  1. PCT国内申请,权利要求书已公开。
CN202280005157.6A 2021-08-17 2022-08-17 病毒制剂、用于配制病毒制剂的溶液及其用途 Pending CN115989321A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110943226 2021-08-17
CN2021109432265 2021-08-17
PCT/CN2022/113153 WO2023020556A1 (zh) 2021-08-17 2022-08-17 病毒制剂、用于配制病毒制剂的溶液及其用途

Publications (1)

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CN115989321A true CN115989321A (zh) 2023-04-18

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ID=85239436

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CN202280005157.6A Pending CN115989321A (zh) 2021-08-17 2022-08-17 病毒制剂、用于配制病毒制剂的溶液及其用途

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CN (1) CN115989321A (zh)
WO (1) WO2023020556A1 (zh)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9908015A (pt) * 1998-02-17 2001-04-24 Schering Corp Composições que compreendem vìrus e métodos para concentração de preparações de vìrus
CN101163794A (zh) * 2005-03-01 2008-04-16 细胞基因体系公司 具有提高的贮存稳定性的治疗用病毒制剂
US20130216499A1 (en) * 2012-02-17 2013-08-22 Wenlin Huang Compositions of recombinant human endostatin adenovirus injections and methods of production
WO2017070110A1 (en) * 2015-10-19 2017-04-27 Cold Genesys, Inc. Methods of treating solid or lymphatic tumors by combination therapy
EP3246410A1 (en) * 2016-05-19 2017-11-22 Klinikum rechts der Isar der Technischen Universität München Vsv/ndv hybrid viruses for oncolytic therapy of cancer
CN110577585A (zh) * 2018-06-07 2019-12-17 中国医学科学院基础医学研究所 水泡型口炎病毒包膜糖蛋白变体及其构建方法和应用

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WO2023020556A1 (zh) 2023-02-23

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