CN115644436A - Compound nutritional preparation suitable for weak people caused by tumor chemotherapy as well as preparation method and application thereof - Google Patents
Compound nutritional preparation suitable for weak people caused by tumor chemotherapy as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a compound nutritional preparation suitable for people suffering from weakness caused by tumor chemotherapy, and a preparation method and application thereof, wherein the compound nutritional preparation suitable for the people suffering from weakness caused by tumor chemotherapy comprises 1-9 parts by weight of blueberry anthocyanin, 1-9 parts by weight of collagen peptide and/or 1-7 parts by weight of glutamine and/or 1-7 parts by weight of beta-hydroxy-beta-methylbutyric acid, and the purity of the blueberry anthocyanin is 10-80%. A compound nutritional preparation suitable for weak people caused by tumor chemotherapy is prepared by a) mixing, b) granulating, c) pulverizing, and d) post-treating, and is suitable for weak people caused by different degrees of chemotherapy and chronic consumptive diseases, and is helpful for promoting patient recovery and improving life quality.
Description
[ technical field ] A method for producing a semiconductor device
The invention relates to the technical field of compound nutritional preparations, in particular to a compound nutritional preparation suitable for weak people caused by tumor chemotherapy and a preparation method and application thereof.
[ background of the invention ]
Chemotherapy of tumors and many chronic wasting diseases cause debilitating patients who often exhibit symptoms such as weight loss, muscle loss, anemia, low immunity, peroxidative damage, gastrointestinal mucosal damage and fatigue. If the disease is not intervened, the disease is aggravated and the prognosis is affected.
For weak people caused by chemotherapy, chronic diseases and the like, western medicine is intervened by medicines at present, and traditional Chinese medicine adopts intervention measures aiming at traditional Chinese medicines prepared and prepared by pathogeny, and although both of the traditional Chinese medicines have certain effects, the traditional Chinese medicines are often accompanied by side effects if used for a long time for treatment.
With the improvement of health consciousness of the national people in China, the concept of self-health care mainly based on prevention, health care, healthy living style, healthy living environment and the like and assisted by disease treatment is continuously strengthened. The trend of nutrition and health care towards food conversion is a future development trend, and the market demand is huge. The nutritional health-care safe food required by different people is prepared by adopting common food, medicinal and edible food, new food raw materials, food additives and the like as raw and auxiliary materials, and has become necessary requirements of consumers.
[ summary of the invention ]
The invention aims to solve the problems in the prior art, and provides a compound nutritional preparation suitable for weak people caused by tumor chemotherapy, a preparation method and application thereof.
In order to achieve the purpose, the invention is realized by the following technical scheme:
the compound nutritional preparation suitable for the weak population caused by tumor chemotherapy comprises 1-9 parts by weight of blueberry anthocyanin, and also comprises 1-9 parts by weight of collagen peptide and/or 1-7 parts by weight of glutamine and/or 1-7 parts by weight of beta-hydroxy-beta-methylbutyric acid. Wherein, the purity of the blueberry anthocyanin is 10-80%.
Preferably, the blueberry anthocyanin and the collagen peptide are mixed in a weight ratio of 3-7 parts, and the collagen peptide and/or the glutamine are mixed in a weight ratio of 4-8 parts, and/or the beta-hydroxy-beta-methylbutyric acid is mixed in a weight ratio of 2-6 parts. Wherein the purity of the blueberry anthocyanin is 20-60%.
Furthermore, the blueberry anthocyanin milk powder comprises 5 parts by weight of blueberry anthocyanin, 5 parts by weight of collagen peptide, 4 parts by weight of glutamine and 4 parts by weight of beta-hydroxy-beta-methylbutyric acid. Wherein the purity of the blueberry anthocyanin is 30-45%.
Furthermore, the blueberry anthocyanin milk powder comprises 5 parts by weight of blueberry anthocyanin, 5 parts by weight of collagen peptide and 4 parts by weight of glutamine. Wherein the purity of the blueberry anthocyanin is 30-45%.
Furthermore, the blueberry anthocyanin powder comprises 5 parts by weight of blueberry anthocyanin, 5 parts by weight of collagen peptide and 4 parts by weight of beta-hydroxy-beta-methylbutyric acid. Wherein the purity of the blueberry anthocyanin is 30-45%.
The preparation method of the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy comprises the following steps:
a) Mixing: weighing 1-9 parts by weight of blueberry anthocyanin, then weighing 1-9 parts by weight of collagen peptide and/or 1-7 parts by weight of glutamine and/or 1-7 parts by weight of beta-hydroxy-beta-methylbutyric acid, and putting into a mixing container to be uniformly mixed to obtain mixed powder; wherein the purity of the blueberry anthocyanin is 10-80%;
b) And (3) granulation: granulating and finishing the mixed powder obtained in the step a) by a wet method or a dry method to obtain mixed particles;
c) Crushing: drying, crushing and sieving the mixed particles obtained in the step b) at low temperature in sequence to obtain sieved powder;
d) And (3) post-treatment: removing metal foreign matters in the screened powder obtained in the step c), carrying out metal detection inspection after internal packaging, and then carrying out disinfection and external packaging to obtain a finished product.
Preferably, in the step b), the number of the whole granules is 10 to 30 meshes.
Preferably, in the step c), the screening mesh number is 80-120 meshes, and the drying temperature is lower than 50 ℃.
Preferably, in the step d), the sterilization mode is ultra-high pressure sterilization, pasteurization or irradiation sterilization.
The compound nutritional preparation suitable for the weak people caused by tumor chemotherapy is used as a main raw material or an auxiliary material and is added into common food, health food or medicines. The common food, health food or medicine includes, but is not limited to, tablets, capsules, granules, oral liquids, hard candies, gel candies, solid beverages, liquid beverages, jellies, baked goods, pastries and the like.
The blueberry has multiple nutritional functions, and the main functional component is blueberry anthocyanin, and the blueberry anthocyanin consists of anthocyanin and one or more sugar molecules, including more than 15 types. The blueberry anthocyanin has the functions of resisting oxidation, enhancing immunity, resisting inflammation, protecting cardiovascular and cerebrovascular vessels, reducing blood sugar and the like, has a good protection function for gastrointestinal tracts, and can effectively prevent gastrointestinal tract injury, chronic colitis and the like caused by stress.
Glutamine is a glutamic acid derivative that exists in the human body. Under stress conditions of diseases, poor nutritional state, high-intensity exercise and the like, the demand of the body for glutamine increases, and self-synthesis cannot meet the demand generally. Glutamine has a number of effects on the body: 1) Providing necessary nitrogen source for organism, promoting protein synthesis in muscle cell, promoting growth and differentiation of muscle cell, increasing strength, and improving endurance; 2) Stimulating the secretion of growth hormone, insulin and testosterone, stimulating the life potential of human body, making the organism in a synthetic state, and preventing the decomposition of muscle protein; 3) Is the basic energy source of gastrointestinal tract lumen cells, enhances the activity of the intestinal tract cells, and can effectively prevent the atrophy of the intestinal tract mucosa.
Beta-hydroxy-beta-methylbutyric acid is a substance naturally occurring in the human body and can be used as a dietary supplement to enhance immunity, also enhance the nitrogen fixation capacity of the human body, maintain the protein level in the body, and promote muscle growth. The supplement of the beta-hydroxy-beta-methylbutyric acid can effectively relieve the muscular atrophy of tumor patients and has certain effect on preventing tumor dyscrasia.
The collagen peptide is rich in arginine and glycine, and the two amino acids are important substances for synthesizing creatine and can promote muscle growth. In addition, the collagen peptide can promote blood microcirculation, is favorable for the transportation of amino acid after protein is taken, improves anaerobic reaction, is also favorable for the growth of muscles, and reduces sarcopenia. In addition, the collagen peptide has oxidation resistance, can reduce free radicals in vivo and reduce the occurrence probability of gastric mucosal hemorrhage and ulcer. Meanwhile, the collagen peptide is also beneficial to the recovery of physical strength after movement.
The invention has the beneficial effects that:
1) All the components of the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy are edible materials allowed by laws and regulations, such as new food raw materials, new food raw material censored food, food additives and the like;
2) The blueberry anthocyanin has high oxidation resistance and can enhance the immunity of an organism, glutamine can promote cell metabolism and has strong capability of protecting gastrointestinal mucosa, collagen peptide can promote physical recovery and prevent muscle loss, and beta-hydroxy-beta-methylbutyric acid can promote protein synthesis and has strong function of relieving muscular atrophy;
4) The compound nutritional preparation prepared by the invention is suitable for weak people caused by tumor chemotherapy, has no toxic or side effect, and is suitable for other people of different ages except infants and pregnant women;
5) The compound nutritional preparation prepared by the invention can be used as a raw material or an auxiliary material, and can be prepared into various foods, health-care foods and medicines such as tablets, capsules, granules, oral liquid, hard candies, gel candies, solid beverages, liquid beverages, jellies, baked foods, cakes and the like.
The features and advantages of the present invention will be described in detail by embodiments in conjunction with the accompanying drawings.
[ description of the drawings ]
FIG. 1 is a flow chart of the preparation of a compound nutritional formulation suitable for use by patients with tumor chemotherapy-induced frailty;
[ detailed description ] A
The first embodiment is as follows:
weighing 5 parts by weight of blueberry anthocyanin (purity of 30-45%), 5 parts by weight of collagen peptide, 4 parts by weight of glutamine and 4 parts by weight of beta-hydroxy-beta-methylbutyric acid, and putting the mixture into a mixing container to be uniformly mixed to obtain mixed powder. Subsequently, the obtained mixed powder was granulated and granulated by a wet method or a dry method to obtain granules having a mesh size of 10 meshes, thereby obtaining mixed granules. Subsequently, the obtained mixed granules are subjected to low-temperature drying below 50 ℃, crushing and sieving in sequence, and the sieve mesh number is 120 to obtain sieve powder. And finally, removing metal foreign matters in the obtained screened powder by an iron remover, carrying out metal detection and inspection after carrying out inner packaging by adopting a food-grade or medicinal-grade PE bag, then carrying out sterilization by adopting an ultrahigh pressure sterilization mode, and carrying out outer packaging to obtain a finished product.
In addition, certain auxiliary materials can be added in the formula, such as nutritive carbohydrate, dietary fiber, vitamin, mineral substance, lipid and the like, and a sweetening agent, essence and the like which can increase palatability.
The second embodiment:
weighing 5 parts by weight of blueberry anthocyanin (purity of 30-45%), 5 parts by weight of collagen peptide and 4 parts by weight of glutamine.
The other steps are the same as those of the first embodiment.
Example three:
weighing 5 parts by weight of blueberry anthocyanin (the purity is 30-45%), 5 parts by weight of collagen peptide and 4 parts by weight of beta-hydroxy-beta-methylbutyric acid.
The other steps are the same as those in the first embodiment.
Example four:
the compound nutritional preparation obtained in the first to third examples and suitable for the weak people caused by tumor chemotherapy is subjected to acute toxicity study to evaluate the safety.
The material method comprises the following steps: 48 healthy clean Kunming mice with the body weight of 22g +/-2 g and half of male and female are taken, after being bred adaptively for 3 days, the mice are randomly divided into four groups, each group comprises 12 mice and half of male and female, one group is a normal control group, and the other three groups are compound nutritional preparation toxicant exposure groups which are prepared in the first to third embodiments and are suitable for the weak people caused by tumor chemotherapy. Dissolving the compound nutritional preparation prepared in the first to third embodiments and suitable for the weak people caused by tumor chemotherapy by using distilled water, and then respectively carrying out intragastric administration on three groups of mice in the infected group according to the maximum dosage of 2000 mg/kg-bw, and carrying out intragastric administration on normal control groups by using distilled water with the same volume, closely observing for 8 hours and recording, and continuously observing for 14 days.
As a result: in 14-day test, the mice in each group do not die, the mice in the infected group are active in behavior, the food intake is constant, the weight is normal, the hair color is bright, the phenomena of convulsion and saliva addiction do not occur, abnormal secretion does not exist around eyes, mouths, noses, ears and anus, and the test result is not obviously different from that of a normal control group. The heart, liver, lung and stomach are not abnormally changed in general anatomy. The results show that the compound nutritional preparation prepared in the first to third embodiments is suitable for the weak people caused by tumor chemotherapy, the maximum tolerated dose is more than 2000mg/kg · bw, and the acute toxicity is very low.
Example five:
the compound nutritional preparation which is suitable for the weak people caused by tumor chemotherapy and obtained in the first to third embodiments is adopted to carry out an influence experiment on chemotherapy model animals so as to evaluate the efficacy.
Establishment of chemotherapy model: 50 healthy and clean male SD rats with the weight of 220 +/-10 g are taken, are adaptively raised for one week, and are randomly divided into 5 groups, and 10 rats in each group are respectively a normal control group, a model group and a compound nutritional preparation intervention group prepared in the first to third embodiments and suitable for the weak people caused by tumor chemotherapy. The normal control group is controlled by intraperitoneal injection of equal volume of normal saline, and rats in other groups are injected with 80mg of cyclophosphamide/(kg bw d) in the abdominal cavity for continuous molding for 3 days, so that the rats generate weak symptoms similar to those caused by human chemotherapy.
Intervention of the compound nutritional preparation: after 3 days of model building, rats in the model group and the normal control group are subjected to intragastric perfusion with equal volume of distilled water, and each intervention group is subjected to intragastric perfusion for 14 days continuously according to the condition that the compound nutritional preparation prepared in the first to third embodiments and suitable for the weak people caused by tumor chemotherapy is subjected to intragastric perfusion at 10mg (calculated by blueberry anthocyanin)/, kg bw.d. After the end of the intervention, the body weight was measured, blood was collected from the retroorbital venous plexus, the activities of Red Blood Cells (RBC), white Blood Cells (WBC), hemoglobin (Hb), and serum superoxide dismutase (SOD) were measured, the spleen and thymus were collected and weighed, and the organ coefficients (spleen weight/body weight, thymus weight/body weight) were calculated.
And (3) test results: compared with the normal control group, the rat hair of the model group has no luster, lassitude, loose stool and emaciation, which are gradually obvious after 7 days of model making, and the hair color, activity degree, loose stool and emaciation degree of each intervention group are better than those of the model group, but are still inferior to those of the normal control group. As shown in table 1 below, the body weight of the rats in the model group was significantly reduced and the body weight of the rats in each intervention group was increased (p < 0.05) compared to the model group, as compared to the normal control group; the weight of the thymus and the spleen of the model group is reduced, the ratio of the weight of the spleen to the weight of the thymus to the weight of the spleen is obviously lower than that of the normal group, and the ratio of the weight of the spleen to the weight of the thymus of each intervening group is obviously higher than that of the model group. As the spleen and the thymus are important immune organs, the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy has the function of enhancing the immunity. Referring to the following table 2, compared with a normal control group, rats RBC, WBC and Hb in the model group are remarkably reduced, and three indexes of the intervention group are higher than those in the model group, which shows that the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy has a certain protection effect on a hematopoietic system. And compared with a normal control group, the SOD of the rats in the model group is obviously reduced, and the SOD of each group is interfered to be increased (p is less than 0.05) compared with the SOD of the model group, which shows that the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy has certain antioxidation. In addition, compared with the indexes of the compound nutritional preparation prepared in the first to third examples and suitable for the weak people caused by tumor chemotherapy, the first example tends to have stronger effects than the second and third examples.
The results show that for the animals treated by chemotherapy, the intervention of the compound preparation can increase the weight of the animals, enhance the oxidation resistance, improve the anemia symptoms and improve the immunity. The compound nutritional preparation suitable for the weak people caused by tumor chemotherapy disclosed by the invention has the effect of improving the symptoms of chemotherapy animals.
TABLE 1 Effect of the Compound nutritional formulation prepared in examples one to three, suitable for use by people with weakness due to tumor chemotherapy, on body weight, spleen index and thymus index of chemotherapy-model animals
# Comparison with the Normal group, p<0.05 × comparison with model group, p<0.05
TABLE 2 influence of the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy on the blood picture and antioxidant capacity of chemotherapy model animals prepared in examples one to three
# Comparison with the Normal group, p<0.05 × comparison with model group, p<0.05
The above embodiments are illustrative of the present invention, and are not intended to limit the present invention, and any simple modifications of the present invention are within the scope of the present invention.
Claims (10)
1. The compound nutritional preparation suitable for the weak people caused by tumor chemotherapy is characterized by comprising the following components in percentage by weight: comprises 1 to 9 weight parts of blueberry anthocyanin, and 1 to 9 weight parts of collagen peptide and/or 1 to 7 weight parts of glutamine and/or 1 to 7 weight parts of beta-hydroxy-beta-methylbutyric acid.
2. The compound nutritional preparation suitable for the frail population caused by tumor chemotherapy according to claim 1, wherein: comprises 3 to 7 parts by weight of blueberry anthocyanin, and also comprises 4 to 8 parts by weight of collagen peptide and/or 2 to 6 parts by weight of glutamine and/or 2 to 6 parts by weight of beta-hydroxy-beta-methylbutyric acid.
3. The compound nutritional preparation suitable for the frail population caused by tumor chemotherapy as claimed in claim 2, wherein: the blueberry anthocyanin milk comprises 5 parts by weight of blueberry anthocyanin, 5 parts by weight of collagen peptide, 4 parts by weight of glutamine and 4 parts by weight of beta-hydroxy-beta-methylbutyric acid.
4. The compound nutritional preparation suitable for the frail population caused by tumor chemotherapy as claimed in claim 2, wherein: comprises 5 parts by weight of blueberry anthocyanin, 5 parts by weight of collagen peptide and 4 parts by weight of glutamine.
5. The compound nutritional preparation suitable for the frail people caused by tumor chemotherapy as claimed in claim 2, which is characterized in that: the blueberry anthocyanin powder comprises 5 parts by weight of blueberry anthocyanin, 5 parts by weight of collagen peptide and 4 parts by weight of beta-hydroxy-beta-methylbutyric acid.
6. The preparation method of the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy is characterized by comprising the following steps:
a) Mixing: weighing 1-9 parts by weight of blueberry anthocyanin, then weighing 1-9 parts by weight of collagen peptide and/or 1-7 parts by weight of glutamine and/or 1-7 parts by weight of beta-hydroxy-beta-methylbutyric acid, and putting into a mixing container to be uniformly mixed to obtain mixed powder;
b) And (3) granulation: granulating and finishing the mixed powder obtained in the step a) by a wet method or a dry method to obtain mixed particles;
c) Crushing: drying, crushing and screening the mixed particles obtained in the step b) at low temperature in sequence to obtain screened powder;
d) And (3) post-treatment: removing metal foreign matters in the screened powder obtained in the step c), carrying out metal detection inspection after internal packaging, and then carrying out disinfection and external packaging to obtain a finished product.
7. The method for preparing the compound nutritional preparation suitable for the frail people caused by tumor chemotherapy according to claim 6, wherein the method comprises the following steps: in the step b), the number of the whole granules is 10 to 30 meshes.
8. The method for preparing the compound nutritional preparation suitable for the frail people caused by tumor chemotherapy according to claim 6, wherein the method comprises the following steps: in the step c), the screen mesh number is 80-120 meshes, and the drying temperature is lower than 50 ℃.
9. The method for preparing the compound nutritional preparation suitable for the frail people caused by tumor chemotherapy according to claim 6, which is characterized by comprising the following steps: in the step d), the sterilization mode adopts ultrahigh pressure sterilization, pasteurization or irradiation sterilization.
10. The application of the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy is characterized in that: the compound nutritional preparation suitable for the weak people caused by tumor chemotherapy, which is disclosed by any one of claims 1 to 5, is added into common food, health food or medicines as a main raw material or an auxiliary material.
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108391811A (en) * | 2018-03-05 | 2018-08-14 | 北京诺康达医药科技有限公司 | A kind of tumour full nutrition formula food and its application |
| CN109691675A (en) * | 2017-10-20 | 2019-04-30 | 上海永沣医药科技有限公司 | A kind of reinforcing formulation food and preparation method thereof restored suitable for postoperative patient |
| CN110301629A (en) * | 2019-07-03 | 2019-10-08 | 安亦臣(武汉)健康科技有限公司 | A kind of full nutrient solid beverage of tumor patient and preparation method thereof |
| CN111480839A (en) * | 2020-03-26 | 2020-08-04 | 上海复旦奥医医学科技有限公司 | Special clinical nutrition formula for bone cancer and preparation method thereof |
| CN112471503A (en) * | 2020-12-04 | 2021-03-12 | 浙江蓝美生物技术有限公司 | Blueberry powder compound solid preparation capable of enhancing immunity and nutritionally intervening colorectal cancer and preparation method and application thereof |
| CN115067518A (en) * | 2022-06-07 | 2022-09-20 | 广东特芯生物科技有限公司 | Composition for improving immunity of tumor patients |
-
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- 2022-10-28 CN CN202211333330.3A patent/CN115644436A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109691675A (en) * | 2017-10-20 | 2019-04-30 | 上海永沣医药科技有限公司 | A kind of reinforcing formulation food and preparation method thereof restored suitable for postoperative patient |
| CN108391811A (en) * | 2018-03-05 | 2018-08-14 | 北京诺康达医药科技有限公司 | A kind of tumour full nutrition formula food and its application |
| CN110301629A (en) * | 2019-07-03 | 2019-10-08 | 安亦臣(武汉)健康科技有限公司 | A kind of full nutrient solid beverage of tumor patient and preparation method thereof |
| CN111480839A (en) * | 2020-03-26 | 2020-08-04 | 上海复旦奥医医学科技有限公司 | Special clinical nutrition formula for bone cancer and preparation method thereof |
| CN112471503A (en) * | 2020-12-04 | 2021-03-12 | 浙江蓝美生物技术有限公司 | Blueberry powder compound solid preparation capable of enhancing immunity and nutritionally intervening colorectal cancer and preparation method and application thereof |
| CN115067518A (en) * | 2022-06-07 | 2022-09-20 | 广东特芯生物科技有限公司 | Composition for improving immunity of tumor patients |
Non-Patent Citations (1)
| Title |
|---|
| 冷吉燕;张婧;邵明柏;: "蓝莓花色苷的研究进展", 中国老年学杂志, no. 17, pages 2 - 3 * |
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