CN115531241A - Collagen mask and production method thereof - Google Patents

Collagen mask and production method thereof Download PDF

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Publication number
CN115531241A
CN115531241A CN202211235275.4A CN202211235275A CN115531241A CN 115531241 A CN115531241 A CN 115531241A CN 202211235275 A CN202211235275 A CN 202211235275A CN 115531241 A CN115531241 A CN 115531241A
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Prior art keywords
collagen
water
percent
finished product
skin
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CN202211235275.4A
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Inventor
谢三浦
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Shenzhen Shiting Tiger Biotechnology Co ltd
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Shenzhen Shiting Tiger Biotechnology Co ltd
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Priority to CN202211235275.4A priority Critical patent/CN115531241A/en
Publication of CN115531241A publication Critical patent/CN115531241A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a collagen facial mask, which comprises a solvent, a skin conditioner and a humectant; also comprises antiseptic, which comprises hexamidine dihydrochloride; the solvent is water; the humectant is one or more of panthenol, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate and tremella polysaccharide; the collagen facial mask and the production method adopt the carboxymethyl chitosan to replace the chitosan, introduce carboxymethyl, destroy the formation of hydrogen bonds in chitosan molecules, increase the water solubility of the collagen facial mask, can be dissolved in pH neutral aqueous solution, and show excellent anti-inflammatory and itching relieving characteristics.

Description

Collagen mask and production method thereof
Technical Field
The invention relates to the technical field of skin care, in particular to a collagen mask and a production method thereof.
Background
The chitosan maintains cationic groups, increases the solubility under an acidic condition, is often used as a raw material of cosmetics, has good biocompatibility, obvious bacteriostatic and hemostatic effects and obvious effect of promoting the growth of skin fibroblasts, but also has certain limitations: can be dissolved in acid and can not be dissolved in water solution with neutral pH, so that the cosmetic can not be applied to conventional cosmetic emulsion and water aqua products. Therefore, the collagen facial mask and the production method are provided.
Disclosure of Invention
The invention aims to provide a collagen mask and a production method thereof, which aim to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a collagen facial mask comprises solvent, skin conditioner and humectant.
Preferably, the composition also comprises a preservative which is hexamidine dihydrochloride.
Preferably, the solvent is water.
Preferably, the humectant is one or more of panthenol, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate and tremella polysaccharide.
Preferably, the skin conditioning agent is one or more of a first skin conditioning agent, a second skin conditioning agent, carboxymethyl chitosan, beta-glucan and soluble collagen;
the first skin conditioning agent consists of water, collagen, 1, 2-hexanediol and hyaluronic acid, wherein the proportion of water in the first skin conditioning agent is 86.80 percent, the proportion of collagen is 9.56 percent, the proportion of 1, 2-hexanediol is 3.00 percent, and the proportion of hyaluronic acid is 0.64 percent;
the second skin conditioner consists of hydrolyzed collagen and dipeptide-1, wherein the hydrolyzed collagen accounts for 98.00 percent and the dipeptide-1 accounts for 2.00 percent in the second skin conditioner.
A production method of a collagen mask comprises the following steps:
firstly, washing an emulsifying pot, a container and a valve tool with sterilized water with the temperature of more than 80 ℃.
Step two, dissolving the hexamidine dihydrochloride and water uniformly in advance according to the weight ratio of 1.
And step three, sequentially putting water, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate, tremella polysaccharide and carboxymethyl chitosan into a main emulsifying pot, heating to 80 ℃, and stirring for dissolving.
And step four, after stirring uniformly, starting cooling water, and stirring for cooling.
Step five, cooling to 60 ℃, adding the first panthenol, the second skin conditioner and the beta-glucan, uniformly stirring, and continuously cooling;
step six, cooling to 40 ℃, adding a first skin conditioner and soluble collagen, stirring uniformly, slowly adding the raw materials in the step two, stirring uniformly, continuously cooling to room temperature, defoaming, discharging to form a semi-finished product;
seventhly, sampling and detecting, wherein after the semi-finished product is detected to be qualified, the semi-finished product is transferred to a qualified area in a semi-finished product standing room;
step eight, filling to form a secondary finished product;
and step nine, packaging to form a finished product.
Compared with the prior art, the invention has the beneficial effects that:
1. carboxymethyl chitosan is adopted to replace chitosan, and carboxymethyl is introduced to destroy the formation of hydrogen bonds in chitosan molecules, so that the water solubility of the chitosan is increased, the chitosan can be dissolved in pH neutral aqueous solution, and excellent anti-inflammatory and itching relieving characteristics are shown.
2. The water-absorbing agent contains polar hydrophilic groups such as hydroxyl, amino, carboxyl and the like, so that the water-absorbing property is stronger, and the water-absorbing property is enhanced along with the increase of the substitution degree of carboxymethyl, thereby being beneficial to moisture preservation;
3. part of acetylamino is reserved, which is beneficial to spreadability and skin feel.
Detailed Description
The described embodiments are only some embodiments of the invention, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
The invention provides a technical scheme that: a collagen facial mask comprises solvent, skin conditioner, humectant and antiseptic, and is prepared from hexamidine dihydrochloride, wherein the solvent is water.
Example two
The difference between the embodiment and the first embodiment is that the humectant is one or more of panthenol, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate and tremella polysaccharide.
The tremella polysaccharide is a plant-derived high-efficiency humectant, has a moisturizing effect superior to that of hyaluronic acid, and is the only one million molecular weight natural moisturizing material at present. It has the functions of keeping moisture, resisting senility and raising skin feeling, and has the main active component of isoglycan protein nucleic acid compound.
The tremella polysaccharide comprises main chain mannose, side chain fucose, xylose, glucuronic acid, and a synthetic body forming amino acid and nucleic acid. Tremella polysaccharides are acidic heteropolysaccharides having a degree of polymerization (m.w) of about 100 ten thousand.
The tremella polysaccharide is similar to hyaluronic acid water solution, and is tasteless, odorless, colorless and transparent high viscosity liquid. Can resist external influence, and has no change in acid, alkali, and heat effects.
EXAMPLE III
This example differs from example one in that the skin conditioning agent is one or more of a first skin conditioning agent, a second skin conditioning agent, carboxymethyl chitosan, beta-glucan, and soluble collagen;
the first skin conditioning agent consists of water, collagen, 1, 2-hexanediol and hyaluronic acid, wherein the proportion of water in the first skin conditioning agent is 86.80 percent, the proportion of collagen is 9.56 percent, the proportion of 1, 2-hexanediol is 3.00 percent, and the proportion of hyaluronic acid is 0.64 percent;
the second skin conditioner consists of hydrolyzed collagen and dipeptide-1, wherein the hydrolyzed collagen accounts for 98.00 percent and the dipeptide-1 accounts for 2.00 percent in the second skin conditioner.
A production method of a collagen mask comprises the following steps:
firstly, washing an emulsifying pot, a container and a valve tool with sterilized water with the temperature of more than 80 ℃.
Step two, dissolving the hexamidine dihydrochloride and water uniformly in an amount of 1.
And step three, sequentially putting water, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate, tremella polysaccharide and carboxymethyl chitosan into a main emulsifying pot, heating to 80 ℃, and stirring for dissolving.
And step four, after stirring uniformly, starting cooling water, and stirring for cooling.
Step five, cooling to 60 ℃, adding the first panthenol, the second skin conditioner and the beta-glucan, uniformly stirring, and continuously cooling;
step six, cooling to 40 ℃, adding a first skin conditioner and soluble collagen, stirring uniformly, slowly adding the raw materials in the step two, stirring uniformly, continuously cooling to room temperature, defoaming, discharging to form a semi-finished product;
seventhly, sampling and detecting, wherein after the semi-finished product is detected to be qualified, the semi-finished product is transferred to a qualified area in a semi-finished product standing room;
step eight, filling to form a secondary finished product;
and step nine, packaging to form a finished product.
The purpose of the various raw material uses is shown in the following table:
Figure BDA0003883384410000041
Figure BDA0003883384410000051
the formula table is as follows:
Figure BDA0003883384410000052
sensory indices are given in the following table:
inspection item Index (I)
Colour(s) Slight white color
Traits Liquid, method for producing the same and use of the same
Smell(s) Has characteristic odor of raw material
The microorganism and physicochemical indexes and quality control measures thereof are shown in the following table:
Figure BDA0003883384410000053
Figure BDA0003883384410000061
it is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A collagen mask is characterized by comprising a solvent, a skin conditioner and a humectant.
2. The collagen mask according to claim 1, further comprising an antiseptic agent selected from the group consisting of hexamidine dihydrochloride.
3. The collagen mask pack according to claim 1, wherein said solvent is water.
4. The collagen mask according to claim 1, wherein said moisturizer is one or more of panthenol, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate, and Tremella polysaccharide.
5. The collagen mask as claimed in claim 1, wherein said skin conditioning agent is one or more of a first skin conditioning agent, a second skin conditioning agent, carboxymethyl chitosan, β -glucan and soluble collagen;
the first skin conditioning agent consists of water, collagen, 1, 2-hexanediol and hyaluronic acid, wherein the proportion of water in the first skin conditioning agent is 86.80 percent, the proportion of collagen is 9.56 percent, the proportion of 1, 2-hexanediol is 3.00 percent, and the proportion of hyaluronic acid is 0.64 percent;
the second skin conditioner consists of hydrolyzed collagen and dipeptide-1, wherein the hydrolyzed collagen accounts for 98.00 percent and the dipeptide-1 accounts for 2.00 percent in the second skin conditioner.
6. A production method of a collagen mask is characterized by comprising the following steps: the method comprises the following steps:
firstly, cleaning an emulsifying pot, a container and a valve tool by using sterilized water with the temperature of more than 80 ℃.
Step two, dissolving the hexamidine dihydrochloride and water uniformly in advance according to the weight ratio of 1.
And step three, sequentially putting water, 1, 2-pentanediol, 1, 2-hexanediol, sodium hyaluronate, tremella polysaccharide and carboxymethyl chitosan into a main emulsifying pot, heating to 80 ℃, and stirring for dissolving.
And step four, after stirring uniformly, starting cooling water, and stirring for cooling.
Step five, cooling to 60 ℃, adding the first panthenol, the second skin conditioner and the beta-glucan, uniformly stirring, and continuously cooling;
step six, cooling to 40 ℃, adding a first skin conditioner and soluble collagen, stirring uniformly, slowly adding the raw materials in the step two, stirring uniformly, continuously cooling to room temperature, defoaming, discharging to form a semi-finished product;
seventhly, sampling and detecting, wherein after the semi-finished product is detected to be qualified, the semi-finished product is transferred to a qualified area between semi-finished product standing;
step eight, filling to form a secondary finished product;
and step nine, packaging to form a finished product.
CN202211235275.4A 2022-10-10 2022-10-10 Collagen mask and production method thereof Pending CN115531241A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320355A (en) * 2017-07-27 2017-11-07 广州赛莱拉干细胞科技股份有限公司 A kind of collagen protein face and preparation method thereof
CN110559238A (en) * 2019-10-16 2019-12-13 湖南佰诺酒业有限公司 pure polypeptide water light facial mask of red bayberry essence

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320355A (en) * 2017-07-27 2017-11-07 广州赛莱拉干细胞科技股份有限公司 A kind of collagen protein face and preparation method thereof
CN110559238A (en) * 2019-10-16 2019-12-13 湖南佰诺酒业有限公司 pure polypeptide water light facial mask of red bayberry essence

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国产普通化妆品备案信息: "KinJi勤肌胶原蛋白面膜", pages 1, Retrieved from the Internet <URL:https://hzpba.nmpa.gov.cn/gccx/chakan.html?prodId=976530398269931520&gb=G> *

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