CN115444134A - 一种蓝莓叶黄素酯咀嚼片及制备方法 - Google Patents
一种蓝莓叶黄素酯咀嚼片及制备方法 Download PDFInfo
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Abstract
本发明公开了一种蓝莓叶黄素酯咀嚼片及制备方法,包括以下重量份的原料:蓝莓粉6~8份,植脂末3~8份,叶黄素酯9~11份,抗性糊精3~4份,D‑甘露糖醇4~8份,微晶纤维素2~4份,硬脂酸镁2~3份,胡萝卜素1~2份,抗坏血酸钙2~3份,薄荷脑1~2份,枸杞粉2~4份,DHA藻油粉3~5份,胶原蛋白粉2~3份,麦芽糊精5~8份,玉米淀粉6~9份。本发明具有显著的改善视疲劳的作用,并且口感好,味道佳,还具有促消化,美容养颜,增强免疫力,改善骨质疏松的功效。
Description
技术领域
本发明属于保健食品技术领域,更具体的说是涉及一种蓝莓叶黄素酯咀嚼片及制备方法。
背景技术
视疲劳又称为眼疲劳,多是长时间用眼后导致出现眼部不适、视觉障碍、疲倦等症状的疾病,如近距离用眼时,视力模糊、重影、字行重叠、文字跳跃等;看远处时,需片刻才能逐渐看清。视疲劳无器质性病变,与用眼习惯、所处环境和自身体质等有关。
随着食品保健行业的发展,已经受到越来越多的人的关注。而将保健食品应用于缓解视疲劳,是食品保健领域一项重要的研究方向。目前市场上存在着各种各样的缓解视疲劳的药物或是保健品,但是大多数药物中含有毒素或是带有副作用,并且味道不适口,无法引起食欲和乐趣。
发明内容
有鉴于此,本发明提供了一种蓝莓叶黄素酯咀嚼片及制备方法,具有显著的改善视疲劳的作用,并且口感好,味道佳,还具有促消化,美容养颜,增强免疫力,改善骨质疏松的功效。
为了实现上述目的,本发明采用如下技术方案:
一种蓝莓叶黄素酯咀嚼片,包括以下重量份的原料:蓝莓粉6~8份,植脂末3~8份,叶黄素酯9~11份,抗性糊精3~4份,D-甘露糖醇4~8份,微晶纤维素2~4份,硬脂酸镁2~3份,胡萝卜素1~2份,抗坏血酸钙2~3份,薄荷脑1~2份,枸杞2~4份,胶原蛋白粉2~3份,玉米淀粉6~9份,DHA藻油粉3~5份。
进一步的,包括以下重量份的原料:蓝莓粉7份,植脂末5份,叶黄素酯10份,抗性糊精3.5份,D-甘露糖醇6份,微晶纤维素3份,硬脂酸镁1.5份,胡萝卜素1.5份,抗坏血酸钙2.5份,薄荷脑1.5份,枸杞粉3份,胶原蛋白粉2.5份,玉米淀粉7份,DHA藻油粉4份。
进一步的,包括以下重量份的原料:蓝莓粉6份,植脂末8份,叶黄素酯11份,抗性糊精3份,D-甘露糖醇4份,微晶纤维素4份,硬脂酸镁3份,胡萝卜素2份,抗坏血酸钙2份,薄荷脑2份,枸杞粉2份,胶原蛋白粉3份,玉米淀粉6份,DHA藻油粉5份。
进一步的,包括以下重量份的原料:蓝莓粉8份,植脂末3份,叶黄素酯9份,抗性糊精4份,D-甘露糖醇8份,微晶纤维素2份,硬脂酸镁2份,胡萝卜素1份,抗坏血酸钙3份,薄荷脑1份,枸杞粉4份,胶原蛋白粉2份,玉米淀粉9份,DHA藻油粉3份。
一种蓝莓叶黄素酯咀嚼片的制备方法,包括如下步骤:
(1)按上述原料重量比例称取各组分原料;
(2)制备混合粉末:将上述蓝莓粉,植脂末,叶黄素酯,D-甘露糖醇,微晶纤维素,硬脂酸镁,胡萝卜素,抗坏血酸钙,薄荷脑,枸杞,胶原蛋白粉原料加入混合机中,混合搅拌均匀后,出料,制备得到混合粉末,备用;
(3)将抗性糊精、DHA藻油粉与玉米淀粉进行等量梯度加法稀释3次后加入步骤(2)制得的混合粉末中,搅拌充分混合均匀,得到混匀粉末;
(4)过筛:将步骤(3)中得到的混匀粉末干燥后过筛;
(5)压片成型:将步骤(4)中干燥过筛的混匀粉末加入到压片机内,制备得到蓝莓叶黄素酯咀嚼片。
进一步的,步骤(2)中,混合机采用V型混合机,混合机的混合时间为35~40min。
进一步的,步骤(4)中,干燥处理时的温度为45~50℃,干燥时间为2~3h。
进一步的,步骤(4)中,过筛为过40~60目筛。
蓝莓为一种富含营养价值的水果,富含大量的花青素,以及丰富的多种维生素和各种对机体有利的矿物质等元素。它的功效是提高视力、抗氧化、抗衰老以及美容养颜,保护眼睛。还可以对延缓脑神经衰老、提高记忆力的功效、加固血管、预防心脏病、预防癌症等有明显的作用。
植脂末能改善食品的内部组织,增香增脂,使口感细腻,润滑厚实,可以使人体血液中的低密度脂蛋白增加,高密度脂蛋白减少,诱发血管硬化,增加心脏病、脑血管意外的危险。
叶黄素酯为一种重要的脂肪酸脂,有类似胡萝卜素的作用。叶黄素酯具有抗氧化,有滤过蓝光的作用,对眼睛发育有较好的营养作用。可以预防紫外线或手机蓝光对眼睛的伤害,对眼睛视网膜有保护作用。叶黄素酯具有保护视力,缓解眼疲劳,可以治疗视力模糊,眼部干涩,眼睛痛,畏光,角膜发红等病症。有预防黄斑变性等作用。
抗性糊精由淀粉加工而成,是将焙烤糊精的难消化成分用工业技术提取处理并精炼而成的一种低热量葡聚糖,属于低分子水溶性膳食纤维,可以提高营养素的利用率和促进对钙、铁、锌等微量元素的吸收。
D-甘露糖醇作为一种低热量功能性甜味剂,用作保湿剂,营养增补剂及组织改良剂。口感比较好,不会影响食品的味道,并可以改善苦味。
微晶纤维素作稀释剂和粘合剂,在高温加工过程中能稳定泡沫和乳状液;形成似油膏质构的凝胶;提高果胶和淀粉凝胶的耐热性;提高黏附力。
硬脂酸镁作为一种药用辅料,可作固体制剂的成膜包衣材料、胶体液体制剂的增稠剂、混悬剂。
胡萝卜素含有大量的胡萝卜素,能起到补肝明目的作用;胡萝卜中还含有多种营养素与抗氧化成分,具有提高机体免疫力的功能;胡萝卜可以使肠道充分的蠕动,利于通便,并能够在防止癌症的发生方面起到一定的作用。
抗坏血酸钙可以预防骨质疏松,降低血压,并可以阻止癌细胞的DNA的合成,对恶性肿瘤有抑制作用,可用于癌症的临床辅助治疗。
薄荷脑医药上用作刺激药,作用于皮肤或粘膜,有清凉止痒作用;内服可作为驱风药,用于头痛及鼻、咽、喉炎症等。
枸杞子含有多种氨基酸,并含有甜菜碱、玉蜀黍黄素、酸浆果红素等特殊营养成分,使其具有非常好的保健功效。具有甘平质润,平补肝肾,滋补强壮的作用。
胶原蛋白动物***中的主要成分,也是哺乳动物体内含量最多、分布最广的功能性蛋白,抑制黑色素的产生,使皮肤中的胶原蛋白活性增强,保持角质层水分以及纤维结构的完整性,促进皮肤组织的新陈代谢,对皮肤产生良好的滋润保湿、消皱美容作用,并且能够有效防止骨质疏松。
玉米淀粉含有亚油酸和维生素E,能使人体内胆固醇水平降低,从而减少动脉硬化的发生;含钙、铁质较多,可防止高血压、冠心病;有丰富的谷胱甘肽,这是一种抗癌因子,在人体内能与多种外来的化学致癌物质相结合,使其失去毒性,然后通过消化道排出体外。粗磨的玉米面中含有大量的赖氨酸,可抑制肿瘤生长;含有微量元素硒,硒能加速人体内氧化物分解,抑制恶性肿瘤;含有丰富的膳食纤维,能促进肠蠕动,缩短食物通过消化道的时间,减少有毒物质的吸收和致癌物质对结肠的刺激,因而可减少结肠癌的发生。
DHA藻油粉是将DHA藻油,添加麦芽糊精、乳清蛋白、天然Ve等原辅料,通过微囊包埋技术,喷雾制成粉末状(粉剂),内含DHA7%和10%两种,以利于人体吸收。
本发明的有益效果在于:
本发明蓝莓粉、植脂末、叶黄素酯、抗性糊精、D-甘露糖醇、微晶纤维素、硬脂酸镁、胡萝卜素、抗坏血酸钙、薄荷脑、枸杞、胶原蛋白粉、玉米淀粉以及DHA藻油粉进行合理配伍,不仅对眼睛有良好的保健作用,能够有效改善眼酸痛、眼胀、畏光、视物模糊、眼干涩、异物感、流泪等眼疲劳症状及提高夜间视力,并且原料中富含蛋白质、维生素、矿物质,有利于提高使用者的免疫力,改善骨质疏松,并具有美容养颜的作用;此外制成的蓝莓叶黄素酯咀嚼片口感好,有营养,无毒害,有利于人们的身体健康,满足人们追求健康生活的需求,有利于产品推广。
具体实施方式
下面将结合本发明的实施例中,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1
本实施例提供了一种蓝莓叶黄素酯咀嚼片,包括以下重量份的原料:蓝莓粉7份,植脂末5份,叶黄素酯10份,抗性糊精3.5份,D-甘露糖醇6份,微晶纤维素3份,硬脂酸镁1.5份,胡萝卜素1.5份,抗坏血酸钙2.5份,薄荷脑1.5份,枸杞粉3份,胶原蛋白粉2.5份,玉米淀粉7份,DHA藻油粉4份。
一种蓝莓叶黄素酯咀嚼片的制备方法,包括如下步骤:
(1)按实施例1的原料重量比例称取各组分原料;
(2)制备混合粉末:将上述蓝莓粉,植脂末,叶黄素酯,D-甘露糖醇,微晶纤维素,硬脂酸镁,胡萝卜素,抗坏血酸钙,薄荷脑,枸杞,胶原蛋白粉原料加入混合机中,混合搅拌均匀后,出料,制备得到混合粉末,备用;其中混合机采用V型混合机,混合机的混合时间为35~40min。
(3)将抗性糊精、DHA藻油粉与玉米淀粉进行等量梯度加法稀释3次后加入步骤(2)制得的混合粉末中,搅拌充分混合均匀,得到混匀粉末;
(4)过筛:将步骤(3)中得到的混匀粉末干燥后过筛;干燥处理时的温度为45~50℃,干燥时间为2~3h。
(5)压片成型:将步骤(4)中干燥过筛的混匀粉末加入到压片机内,制备得到蓝莓叶黄素酯咀嚼片。
实施例2
本实施例提供了一种蓝莓叶黄素酯咀嚼片,包括以下重量份的原料:蓝莓粉6份,植脂末8份,叶黄素酯11份,抗性糊精3份,D-甘露糖醇4份,微晶纤维素4份,硬脂酸镁3份,胡萝卜素2份,抗坏血酸钙2份,薄荷脑2份,枸杞粉2份,胶原蛋白粉3份,玉米淀粉6份,DHA藻油粉5份。
一种蓝莓叶黄素酯咀嚼片的制备方法,包括如下步骤:
(1)按实施例2的原料重量比例称取各组分原料;
(2)制备混合粉末:将上述蓝莓粉,植脂末,叶黄素酯,D-甘露糖醇,微晶纤维素,硬脂酸镁,胡萝卜素,抗坏血酸钙,薄荷脑,枸杞,胶原蛋白粉原料加入混合机中,混合搅拌均匀后,出料,制备得到混合粉末,备用;其中混合机采用V型混合机,混合机的混合时间为35~40min。
(3)将抗性糊精、DHA藻油粉与玉米淀粉进行等量梯度加法稀释3次后加入步骤(2)制得的混合粉末中,搅拌充分混合均匀,得到混匀粉末;
(4)过筛:将步骤(3)中得到的混匀粉末干燥后过筛;干燥处理时的温度为45~50℃,干燥时间为2~3h。
(5)压片成型:将步骤(4)中干燥过筛的混匀粉末加入到压片机内,制备得到蓝莓叶黄素酯咀嚼片。
实施例3
本实施例提供了一种蓝莓叶黄素酯咀嚼片,包括以下重量份的原料:蓝莓粉8份,植脂末3份,叶黄素酯9份,抗性糊精4份,D-甘露糖醇8份,微晶纤维素2份,硬脂酸镁2份,胡萝卜素1份,抗坏血酸钙3份,薄荷脑1份,枸杞粉4份,胶原蛋白粉2份,玉米淀粉9份,DHA藻油粉3份。
一种蓝莓叶黄素酯咀嚼片的制备方法,包括如下步骤:
(1)按实施例3的原料重量比例称取各组分原料;
(2)制备混合粉末:将上述蓝莓粉,植脂末,叶黄素酯,D-甘露糖醇,微晶纤维素,硬脂酸镁,胡萝卜素,抗坏血酸钙,薄荷脑,枸杞,胶原蛋白粉原料加入混合机中,混合搅拌均匀后,出料,制备得到混合粉末,备用;其中混合机采用V型混合机,混合机的混合时间为35~40min。
(3)将抗性糊精、DHA藻油粉与玉米淀粉进行等量梯度加法稀释3次后加入步骤(2)制得的混合粉末中,搅拌充分混合均匀,得到混匀粉末;
(4)过筛:将步骤(3)中得到的混匀粉末干燥后过筛;干燥处理时的温度为45~50℃,干燥时间为2~3h。
(5)压片成型:将步骤(4)中干燥过筛的混匀粉末加入到压片机内,制备得到蓝莓叶黄素酯咀嚼片。
实验例
1、受试者选择
选择长期用眼,视力易疲劳的成人作为受试人群。凡符合上述条件而自愿参加并保证配合者均纳入试验;对不符合纳入年龄标准的受试者,对保健食品过敏者,患有感染性眼部疾病者,患有心血管慢性疾病等均不纳入数据统计。其中,对照组200例,试验组200例。
2、试验组与对照组给样
试验组1:给予由实施例1制成的蓝莓叶黄素酯咀嚼片,每次1片,每日3次。
试验组2:给予由实施例2制成的蓝莓叶黄素酯咀嚼片,每次1片,每日3次。
试验组3:给予由实施例3制成的蓝莓叶黄素酯咀嚼片,每次1片,每日3次。
对照组:一种压片糖果,包括以下重量份的原料:大蒜多糖8-12份、中药提取物10-15份、硬脂酸镁3-7份;中药提取物是由马齿苋、淡竹叶、茯苓和金银花按照1:1:0.9:0.6的重量比制得的。
制备方法包括如下步骤:
1)将马齿苋、淡竹叶、茯苓和金银花按照重量份混合,加入4倍原料总重量的浓度为80%的乙醇,过滤获得第一提取液;向药渣中再加入3倍药渣重量的浓度为90%的乙醇,过滤得第二提取液;将第一提取液和第二提取液合并,减压浓缩除去乙醇,干燥,得干膏;将干膏放置在超微粉碎机中粉碎2.5h,过筛,得200目的中药提取物;
2)混合:将大蒜多糖、中药提取物和硬脂酸镁混合均匀,得混合料;
3)制粒:将混合料放入摇摆颗粒机中,过14目尼龙筛进行制粒,然后干燥,干燥后的颗粒再次放入摇摆制粒机中进行整粒,过60目筛;
4)压片:将制好的颗粒,用旋转式压片机进行压片,压片进行包装,制得压片糖果。
给予由对照组制成的压片糖果,每次1片,每日3次。
3、效果对比
试验组1-3与对照组的使用效果对比,参见表1。
表1
由表1可知,试验组和对照组受试者视疲劳的症状均得到了良好的改善。试验组与对照组相比,其改善视疲劳症状的效果远远优于对照组。本发明的蓝莓叶黄素酯咀嚼片具有显著的改善视疲劳的作用,并且口感好,味道佳,还具有促消化,美容养颜,增强免疫力,改善骨质疏松的功效。
最后应说明的是:以上实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。
Claims (8)
1.一种蓝莓叶黄素酯咀嚼片,其特征在于,包括以下重量份的原料:蓝莓粉6~8份,植脂末3~8份,叶黄素酯9~11份,抗性糊精3~4份,D-甘露糖醇4~8份,微晶纤维素2~4份,硬脂酸镁2~3份,胡萝卜素1~2份,抗坏血酸钙2~3份,薄荷脑1~2份,枸杞2~4份,胶原蛋白粉2~3份,玉米淀粉6~9份,DHA藻油粉3~5份。
2.根据权利要求1所述的一种蓝莓叶黄素酯咀嚼片,其特征在于,包括以下重量份的原料:蓝莓粉7份,植脂末5份,叶黄素酯10份,抗性糊精3.5份,D-甘露糖醇6份,微晶纤维素3份,硬脂酸镁1.5份,胡萝卜素1.5份,抗坏血酸钙2.5份,薄荷脑1.5份,枸杞粉3份,胶原蛋白粉2.5份,玉米淀粉7份,DHA藻油粉4份。
3.根据权利要求1所述的一种蓝莓叶黄素酯咀嚼片,其特征在于,包括以下重量份的原料:蓝莓粉6份,植脂末8份,叶黄素酯11份,抗性糊精3份,D-甘露糖醇4份,微晶纤维素4份,硬脂酸镁3份,胡萝卜素2份,抗坏血酸钙2份,薄荷脑2份,枸杞粉2份,胶原蛋白粉3份,玉米淀粉6份,DHA藻油粉5份。
4.根据权利要求1所述的一种蓝莓叶黄素酯咀嚼片,其特征在于,包括以下重量份的原料:蓝莓粉8份,植脂末3份,叶黄素酯9份,抗性糊精4份,D-甘露糖醇8份,微晶纤维素2份,硬脂酸镁2份,胡萝卜素1份,抗坏血酸钙3份,薄荷脑1份,枸杞粉4份,胶原蛋白粉2份,玉米淀粉9份,DHA藻油粉3份。
5.一种蓝莓叶黄素酯咀嚼片的制备方法,其特征在于,包括如下步骤:
(1)按权利要求1-4任一项的原料重量比例称取各组分原料;
(2)制备混合粉末:将上述蓝莓粉,植脂末,叶黄素酯,D-甘露糖醇,微晶纤维素,硬脂酸镁,胡萝卜素,抗坏血酸钙,薄荷脑,枸杞,胶原蛋白粉原料加入混合机中,混合搅拌均匀后,出料,制备得到混合粉末,备用;
(3)将抗性糊精、DHA藻油粉与玉米淀粉进行等量梯度加法稀释3次后加入步骤(2)制得的混合粉末中,搅拌充分混合均匀,得到混匀粉末;
(4)过筛:将步骤(3)中得到的混匀粉末干燥后过筛;
(5)压片成型:将步骤(4)中干燥过筛的混匀粉末加入到压片机内,制备得到蓝莓叶黄素酯咀嚼片。
6.根据权利要求5所述的一种蓝莓叶黄素酯咀嚼片的制备方法,其特征在于,步骤(2)中,混合机采用V型混合机,混合机的混合时间为35~40min。
7.根据权利要求5所述的一种蓝莓叶黄素酯咀嚼片的制备方法,其特征在于,步骤(4)中,干燥处理时的温度为45~50℃,干燥时间为2~3h。
8.根据权利要求5所述的一种蓝莓叶黄素酯咀嚼片的制备方法,其特征在于,步骤(4)中,过筛为过40~60目筛。
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CN116076722A (zh) * | 2023-02-17 | 2023-05-09 | 华北制药河北华维健康产业有限公司 | 一种叶黄素β胡萝卜素咀嚼片及其制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108041242A (zh) * | 2017-12-25 | 2018-05-18 | 广州美耕食品有限公司 | 一种蓝莓叶黄素酯片 |
CN108157568A (zh) * | 2017-12-29 | 2018-06-15 | 广东粤微食用菌技术有限公司 | 一种缓解视疲劳的组合糖果及其制备方法和用途 |
CN109645201A (zh) * | 2019-02-22 | 2019-04-19 | 四川益康天成生物科技开发有限公司 | 含有叶黄素和叶黄素酯的组合物、叶黄素压片糖及制备方法和应用 |
CN111227097A (zh) * | 2020-02-27 | 2020-06-05 | 山东祥宏堂医药有限公司 | 一种蓝莓叶黄素酯糖果片剂及制备方法 |
CN111990524A (zh) * | 2020-05-25 | 2020-11-27 | 河南磐康健康管理股份有限公司 | 一种预防与改善视觉疲劳的组合物及其制备方法 |
-
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Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108041242A (zh) * | 2017-12-25 | 2018-05-18 | 广州美耕食品有限公司 | 一种蓝莓叶黄素酯片 |
CN108157568A (zh) * | 2017-12-29 | 2018-06-15 | 广东粤微食用菌技术有限公司 | 一种缓解视疲劳的组合糖果及其制备方法和用途 |
CN109645201A (zh) * | 2019-02-22 | 2019-04-19 | 四川益康天成生物科技开发有限公司 | 含有叶黄素和叶黄素酯的组合物、叶黄素压片糖及制备方法和应用 |
CN111227097A (zh) * | 2020-02-27 | 2020-06-05 | 山东祥宏堂医药有限公司 | 一种蓝莓叶黄素酯糖果片剂及制备方法 |
CN111990524A (zh) * | 2020-05-25 | 2020-11-27 | 河南磐康健康管理股份有限公司 | 一种预防与改善视觉疲劳的组合物及其制备方法 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116076722A (zh) * | 2023-02-17 | 2023-05-09 | 华北制药河北华维健康产业有限公司 | 一种叶黄素β胡萝卜素咀嚼片及其制备方法 |
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