CN115402647A

CN115402647A - Reagent transfer device

Info

Publication number: CN115402647A
Application number: CN202110594608.1A
Authority: CN
Inventors: 朱志华; 黄杰; 李江峰
Original assignee: Guangzhou Wondfo Biotech Co Ltd
Current assignee: Guangzhou Wondfo Biotech Co Ltd
Priority date: 2021-05-28
Filing date: 2021-05-28
Publication date: 2022-11-29
Anticipated expiration: 2041-05-28
Also published as: CN115402647B; EP4094836A1

Abstract

The invention relates to a reagent transfer device, which comprises a reagent container, a first sealing film and a cover body. The reagent container is provided with a first end, which is provided with a first opening communicating with the first chamber of the reagent container. The first sealing film is arranged at the first end and can seal the first opening. When the liquid reagent stored in the reagent container flows out, the needling piece is driven to move, the needling piece is used for ejecting and pressing the soft piece and the first sealing film, the soft piece is not easy to be punctured in the ejecting and pressing process of the needling piece, the first sealing film is punctured when the needling piece is ejected and pressed, the needling piece is wrapped by the soft piece all the time in the process of puncturing the first sealing film, the soft piece can avoid the needling piece from contacting the liquid reagent in the reagent container, the reagent container from being polluted and the reagent container from contacting the needling piece, and the liquid reagent is prevented from volatilizing and diffusing out through the first opening, so that the detection precision can be ensured, and the maintenance and cleaning times of the medical analysis equipment can be reduced.

Description

Reagent transfer device

Technical Field

The invention relates to the technical field of medical instruments, in particular to a reagent transfer device.

Background

A conventional reagent transfer device includes a reagent container for storing a reagent, and during the reagent transfer device is used in a medical analysis apparatus, the reagent container needs to be punctured by a needle-pricked member, so that the reagent stored in the reagent container flows out, and then the liquid reagent flowing out is subjected to relevant detection and analysis processes. The reagent container is tubular, the end face of the tubular shape is provided with a port, the port is usually sealed by a sealing membrane which can be punctured by a puncturing element, when the liquid reagent arranged in the reagent container needs to flow out, the puncturing element is driven by a driving device to press down the puncturing sealing membrane, a puncturing channel opening is formed on the sealing membrane, and the medical analysis equipment transfers the reagent to other flow passages or containers from the puncturing channel opening. This protocol allows for storage of reagents and subsequent transfer of reagents. However, the lancet of the medical analysis apparatus is contaminated by direct contact with the reagent, which reduces the detection accuracy, and requires frequent maintenance and cleaning operations of the medical analysis apparatus.

Disclosure of Invention

Based on this, it is necessary to overcome the defects of the prior art and provide a reagent transferring apparatus which can ensure the detection precision and reduce the maintenance and cleaning times of the medical analysis equipment.

The technical scheme is as follows: a reagent transfer device, comprising: a reagent container having a first end with a first opening communicating with a first chamber of the reagent container; the first sealing film is arranged at the first end and can seal the first opening; the cover body covers the first end, and a soft piece which corresponds to the first opening and is not easy to be punctured by a puncturing piece is arranged on the cover body.

The reagent transfer device drives the needling piece to move when liquid reagent stored in the reagent container flows out outwards as required, the needling piece pushes the soft piece and the first sealing film, the soft piece is not easy to be punctured by the needling piece in the pushing process, the first sealing film is punctured by the needling piece in the pushing process, the needling piece is wrapped by the soft piece all the time in the process of puncturing the first sealing film, the soft piece can avoid the needling piece from contacting the liquid reagent in the reagent container, so that the reagent container can be prevented from being polluted, the reagent container can be prevented from contacting the needling piece, and the liquid reagent can be prevented from volatilizing and diffusing outwards through the first opening. Thus, the detection precision can be ensured, and the maintenance and cleaning times of the medical analysis equipment can be reduced.

In one embodiment, the reagent container is provided with a second end opposite to the first end, the second end being provided with a second opening communicating with the first chamber of the reagent container; the reagent container further comprises a second sealing membrane, the second sealing membrane is arranged at the second end and can seal the second opening; the reagent transfer device further comprises a support, a transition cavity is arranged on the support, the transition cavity is provided with an insertion opening corresponding to the second end, the second end passes through the insertion opening and extends into the transition cavity, and a piercing piece used for piercing the second sealing film is arranged on the bottom wall of the transition cavity.

In one embodiment, the first sealing film is fixed on the end face of the first end in a hot-pressing mode; the second sealing film is fixed on the end face of the second end in a hot-pressing mode.

In one embodiment, the end face of the first end is provided with a first flange surrounding the first opening, and the first sealing film is tightly attached to the first flange; the end face of the second end is provided with a second flange surrounding the second opening, and the second sealing film is tightly attached to the second flange.

In one embodiment, at least one ring of third flange is arranged on the outer wall of the second end in a surrounding mode, and the third flange is in interference fit with the cavity wall of the transition cavity.

In one embodiment, a groove is arranged on the outer wall of the second end in a surrounding manner, and an elastic sleeve is arranged in the groove; the third flange is arranged on the outer wall of the elastic sleeve.

In one embodiment, the reagent transfer device further comprises a frame; the reagent container is arranged on the frame; the frame is adjustably arranged on the support, and is provided with a first working position and a second working position; when the frame is in the first working position, a space is arranged between the second sealing membrane and the puncture member; when the frame receives external driving force and is greater than preset force, the frame moves from the first working position to the second working position under the action of the external driving force, and the second sealing film is punctured by the puncturing piece when the frame moves to the second working position.

In one embodiment, a support column is arranged on the support, a limiting block corresponding to the support column is arranged on the frame, and the limiting block abuts against the support column when the frame is located at the first working position;

the limiting block comprises a guide sleeve and an easily-broken part arranged at one end of the guide sleeve, the supporting column is movably arranged in the guide sleeve and is abutted against the easily-broken part, and when the frame is subjected to external driving force which is larger than preset force, the supporting column enables the easily-broken part to be broken and move out of the guide sleeve; or at least one of the limiting block and the supporting column is an elastic block; or the limiting block is abutted against the supporting column through an elastic block.

In one embodiment, the number of the supporting columns is at least three, the number of the limiting blocks is at least three, and the three supporting columns and the three limiting blocks are arranged in a one-to-one correspondence manner.

In one embodiment, the outer wall of the first end of the reagent container is provided with a plate edge, the frame is provided with an avoiding opening, the reagent container is arranged in the avoiding opening, and the plate edge of the reagent container is arranged on the frame in an overlapping mode.

In one embodiment, the number of the reagent containers is several, and the several reagent containers are connected in sequence; the cover body covers the first ends of the reagent containers, and the soft piece covers the first openings of the reagent containers.

In one embodiment, the reagent transferring device further comprises a supporting member, the supporting member is disposed at the first end, the supporting member is provided with an avoiding hole, the avoiding hole is located opposite to the puncture position of the puncture member, and the supporting member is used for supporting and abutting against the first sealing film.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the invention and, together with the description, serve to explain the invention and not to limit the invention.

In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.

FIG. 1 is a schematic structural diagram of a reagent transfer device according to an embodiment of the present invention;

FIG. 2 is an exploded view of a reagent transfer device according to an embodiment of the present invention;

FIG. 3 is a cross-sectional view of a frame of a reagent transfer device according to an embodiment of the present invention in a first operating position;

FIG. 4 is an enlarged schematic view of FIG. 3 at A;

FIG. 5 is an enlarged view of FIG. 3 at B;

FIG. 6 is a cross-sectional view of a frame of a reagent transfer device according to an embodiment of the present invention in a second operating position;

FIG. 7 is an enlarged schematic view of FIG. 6 at C;

FIG. 8 is an enlarged schematic view of FIG. 6 at D;

FIG. 9 is a schematic structural diagram of a limiting block of the reagent transferring apparatus according to an embodiment of the present invention;

FIG. 10 is a schematic structural diagram of a reagent container according to an embodiment of the present invention;

FIG. 11 is an exploded view of a reagent container according to an embodiment of the present invention;

FIG. 12 is a schematic cross-sectional view of a reagent container according to an embodiment of the present invention;

fig. 13 is an enlarged schematic view of fig. 12 at E.

10. A reagent container; 11. a first end; 111. a first opening; 112. a step; 113. a first flange; 114. a plate edge; 12. a second end; 121. a second opening; 122. a second flange; 123. a groove; 13. a first chamber; 20. a first sealing film; 30. a cover body; 31. a soft member; 40. a needling member; 50. a second sealing film; 60. an elastic sleeve; 61. a third flange; 70. a support; 71. a transition chamber; 711. an insertion opening; 72. a piercing member; 73. a support pillar; 80. a support member; 81. avoiding holes; 90. a frame; 91. a limiting block; 911. a guide sleeve; 912. a breakable portion; 92. avoiding the mouth.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.

Referring to fig. 1, 2, 11 and 12, fig. 1 is a schematic structural diagram of a reagent transfer device according to an embodiment of the present invention, fig. 2 is a schematic exploded structural diagram of a reagent transfer device according to an embodiment of the present invention, fig. 11 is a schematic exploded structural diagram of a reagent container 10 according to an embodiment of the present invention, and fig. 12 is a schematic cross-sectional structural diagram of a reagent container 10 according to an embodiment of the present invention. An embodiment of the present invention provides a reagent transfer device, including: a reagent vessel 10, a first sealing film 20 and a cover 30. The reagent vessel 10 is provided with a first end 11, the first end 11 being provided with a first opening 111 communicating with the first chamber 13 of the reagent vessel 10. The first sealing film 20 is disposed at the first end 11 and can seal the first opening 111. The cover 30 covers the first end 11, and the cover 30 is provided with a soft material 31 corresponding to the first opening 111 and less likely to be punctured by the puncturing material 40.

According to the reagent transfer device, when the liquid reagent stored in the reagent container 10 needs to flow out, the needling member 40 is driven to move, the needling member 40 presses against the soft member 31 and the first sealing film 20, the soft member 31 is not easy to puncture in the pressing process of the needling member 40, the first sealing film 20 is punctured when being pressed by the needling member 40, the first sealing film 20 is always wrapped by the soft member 31 in the process of puncturing the first sealing film 20 by the needling member 40, the soft member 31 can prevent the needling member 40 from contacting the liquid reagent in the reagent container 10, so that the reagent container 10 can be prevented from being polluted, the reagent container 10 can be prevented from contacting the needling member 40, and the liquid reagent can be prevented from volatilizing and diffusing out through the first opening 111. Thus, the detection precision can be ensured, and the maintenance and cleaning times of the medical analysis equipment can be reduced.

It should be noted that the soft component 31 that is not easily punctured by the needle component 40 is specifically a soft rubber with better toughness, such as PU soft rubber, elastic rubber, silica gel, etc., and is not limited herein and may be set according to the requirement.

Referring to fig. 2 to 5, fig. 3 is a cross-sectional view of a frame 90 of a reagent transferring apparatus according to an embodiment of the present invention in a first working position, fig. 4 is an enlarged schematic view of fig. 3 at a, and fig. 5 is an enlarged schematic view of fig. 3 at B. Further, the reagent vessel 10 is provided with a second end 12 opposite the first end 11, the second end 12 being provided with a second opening 121 communicating with the first chamber 13 of the reagent vessel 10. The reagent vessel 10 further comprises a second sealing membrane 50. The second sealing film 50 is disposed at the second end 12 and can seal the second opening 121. Furthermore, the reagent transfer device comprises a holder 70. The support 70 is provided with a transition cavity 71, the transition cavity 71 is provided with an insertion opening 711 corresponding to the second end 12, the second end 12 extends into the transition cavity 71 through the insertion opening 711, and the bottom wall of the transition cavity 71 is provided with a puncturing piece 72 for puncturing the second sealing membrane 50. In this way, in the process of driving the needle-pricker 40 to move so that the needle-pricker 40 is pressed against the soft material 31 and the first sealing membrane 20, the second end 12 of the reagent container 10 moves toward the bottom wall of the transition chamber 71, and the pricking piece 72 contacts the second sealing membrane 50 to prick the second sealing membrane 50, so that both the first sealing membrane 20 and the second sealing membrane 50 are pricked, and the liquid reagent in the reagent container 10 can smoothly flow out of the reagent container 10 into the transition chamber 71.

Referring to fig. 11 to 13, fig. 12 is an enlarged schematic view of fig. 12 at E. In one embodiment, the first sealing film 20 is heat-press fixed to the end face of the first end 11. Thus, after the first sealing film 20 is fixed to the end face of the first end 11 by heat pressing, the first sealing film 20 can seal the first opening 111.

Referring to fig. 11 to 13, in one embodiment, the second sealing film 50 is fixed to the end surface of the second end 12 by heat pressing. Thus, after the second sealing film 50 is fixed on the end face of the second end 12 by hot pressing, the second sealing film 50 can seal the second opening 121.

The first sealing film 20 may also seal the first opening 111 in other manners, such as adhering the first sealing film 20 to the end face of the first end 11, and the like, which is not limited herein. Similarly, the second sealing film 50 can also seal the second opening 121 by other methods, such as adhering the second sealing film 50 to the end face of the second end 12, and so on.

Referring to fig. 11 to 13, in an embodiment, the end surface of the first end 11 is provided with a first flange 113 surrounding the first opening 111, and the first sealing film 20 is tightly attached to the first flange 113. The end face of the second end 12 is provided with a second flange 122 surrounding the second opening 121, and the second sealing film 50 is tightly attached to the second flange 122. In this way, since the first flange 113 surrounding the first opening 111 is provided on the end surface of the first end 11, the first sealing film 20 can more tightly seal the first opening 111 when being fixed to the end surface of the first end 11 by hot pressing, and the sealing performance is better. Similarly, since the second flange 122 surrounding the second opening 121 is provided on the end surface of the second end 12, the second sealing film 50 can more tightly seal the second opening 121 when it is fixed to the end surface of the second end 12 by heat pressing, and the sealing performance is better.

Referring to fig. 13, in one embodiment, at least one third flange 61 is circumferentially disposed on the outer wall of the second end 12. The third flange 61 is in interference engagement with the wall of the transition chamber 71. Thus, after the reagent container 10 is pierced and the liquid reagent flows into the transition cavity 71, the at least one circle of third flange 61 is in interference fit with the wall of the transition cavity 71, so that the reagent container has better sealing performance and can prevent the liquid reagent in the transition cavity 71 from flowing out through the insertion port 711.

Referring to fig. 13, further, a groove 123 is disposed around the outer wall of the second end 12, and the elastic sleeve 60 is disposed in the groove 123. A third flange 61 is provided on the outer wall of the elastic sleeve 60. Particularly, in order to guarantee the sealing effect, the elastic sleeve 60 is soft rubber with good elasticity, such as TPE soft rubber, silica gel, rubber and the like, and is not limited herein and can be set according to actual requirements.

Referring to fig. 3 to 8, fig. 6 is a sectional view of a frame 90 of a reagent transferring apparatus according to an embodiment of the present invention in a second working position, fig. 7 is an enlarged structural view of fig. 6 at C, and fig. 8 is an enlarged structural view of fig. 6 at D. In one embodiment, the reagent transfer device further comprises a frame 90. The reagent vessel 10 is disposed on the frame 90. The frame 90 is adjustably arranged on the support 70, and the frame 90 is provided with a first working position and a second working position; when the frame 90 is in the first working position, a space is provided between the second sealing membrane 50 and the piercing member 72; when the frame 90 is subjected to an external driving force greater than the preset force, the frame 90 moves from the first working position to the second working position under the action of the external driving force, and the second sealing membrane 50 is punctured by the puncturing piece 72 when the frame 90 moves to the second working position. The specific magnitude of the preset force is set according to actual conditions, and is not limited herein. Before the reagent container 10 is not punctured, the frame 90 is in the first working position, the frame 90 supports the reagent container 10 so that a space is formed between the second sealing membrane 50 of the reagent container 10 and the puncturing member 72, therefore, the second sealing membrane 50 cannot be punctured because the puncturing member 72 does not contact the second sealing membrane 50, and the frame 90 needs to be moved from the first working position to the second working position when an external driving force is greater than a preset force, namely, the frame is always in the first working position when the external driving force is smaller than the preset force, so that the sealing membrane of the reagent container 10 can be prevented from being punctured in the assembling process and the transportation process of the reagent transfer device; when the first sealing film 20 and the second sealing film 50 of the reagent container 10 need to be punctured, the needle puncturing piece 40 is driven to move, and the needle puncturing piece 40 presses against the soft piece 31 and the first sealing film 20, on one hand, the first sealing film 20 is punctured by the needle puncturing piece 40, on the other hand, the cover body 30, the reagent container 10 and the frame 90 are pushed by the soft piece 31 to move towards the support 70 when the needle puncturing piece 40 moves, so that the frame 90 is driven by an external driving force to be larger than a preset force, the frame 90 moves from the first working position to the second working position under the action of the external driving force, and the puncturing piece 72 punctures the second sealing film 50 when the frame 90 moves to the second working position.

Referring to fig. 3 to 5, further, a supporting pillar 73 is disposed on the supporting seat 70, a limiting block 91 corresponding to the supporting pillar 73 is disposed on the frame 90, and when the frame 90 is located at the first working position, the limiting block 91 abuts against the supporting pillar 73.

Referring to fig. 3 to 5, in an embodiment, the stopper 91 includes a guide sleeve 911 and a breakable portion 912 disposed at one end of the guide sleeve 911. The supporting column 73 is movably disposed in the guide sleeve 911 and abuts against the breakable portion 912, and when the frame 90 receives an external driving force greater than a preset force, the breakable portion 912 is broken and moves out of the guide sleeve 911 by the supporting column 73. In this way, the frame 90 and the reagent container 10 thereon move from the first operating position to the second operating position in the process of the support column 73 breaking the breakable portion 912 and moving it out of the guide sleeve 911. When the reagent vessel 10 is moved into the second operating position, the piercing member 72 pierces the second sealing membrane 50.

It should be noted that there are many specific design forms of the breakable portion 912, as long as when the frame 90 receives an external driving force greater than a preset force, the support pillar 73 can break the breakable portion 912 and move out of the guide sleeve 911; in addition, when the frame 90 is subjected to an external driving force not greater than a predetermined force, the supporting posts 73 abut against the breakable portions 912, thereby supporting the frame 90 and the reagent containers 10 thereon. For example, the breakable part 912 is a limiting piece arranged at one end of the guide sleeve 911, the edge of the limiting piece is connected with the guide sleeve 911 through at least one breakable strip, when the acting force of the support column 73 on the limiting piece reaches a set value, the breakable strip is broken, the limiting piece is separated from the guide sleeve 911, and thus the support column 73 can break the breakable part 912 and move out of the guide sleeve 911; for another example, the breakable portion 912 is a film, a brittle glass, an easy-to-draw cardboard, or the like fixed to one end of the guide sleeve 911, and when the breakable portion 912 is acted by the support column 73 to reach a set value, the support column 73 can break the breakable portion 912 and move out of the guide sleeve 911.

In another embodiment, the limiting block 91 and the supporting column 73 are not limited to the limiting piece and the breakable portion 912 in the above embodiments, for example, at least one of the limiting block 91 and the supporting column 73 is an elastic block, and when the frame 90 reaches a predetermined force by an external driving force, the limiting block 91 and the supporting block can be deformed and compressed enough to move the frame 90 and the reagent container 10 thereon from the first working position to the second working position, and when the reagent container 10 moves to the second working position, the second sealing film 50 is broken by the breaking member 72. For another example, the limiting block 91 is abutted against the supporting column 73 through an elastic block, and similarly, when the frame 90 reaches a preset force by an external driving force, the elastic block can be deformed and compressed enough to move the frame 90 and the reagent container 10 thereon from the first working position to the second working position, and when the reagent container 10 moves to the second working position, the second sealing film 50 is pierced by the piercing member 72.

As an alternative, the arrangement of the supporting column 73 and the limiting block 91 may be reversed, that is, the supporting column 73 is disposed on the frame 90, and the limiting block 91 is disposed on the support 70.

Referring to fig. 2, in an embodiment, there are at least three supporting columns 73, at least three limiting blocks 91, and the three supporting columns 73 and the three limiting blocks 91 are disposed in a one-to-one correspondence. So, support conflict in at least three stopper 91 through at least three support column 73 corresponds respectively, can realize that frame 90 sets up on support 70 steadily.

It should be noted that the number of the supporting columns 73 may be one, two or another, and is not limited herein. Likewise, the limiting blocks 91 may be one, two or another number, which is not limited herein.

Referring to fig. 2 and 3, in one embodiment, a plate edge 114 is disposed on an outer wall of the first end 11 of the reagent container 10, the frame 90 is disposed with the avoiding opening 92, the reagent container 10 is disposed in the avoiding opening 92, and the plate edge 114 of the reagent container 10 is overlapped on the frame 90.

Referring to fig. 2 and 3, in one embodiment, the number of the reagent containers 10 is several, and several reagent containers 10 are connected in sequence. The cover 30 covers the first ends 11 of the plurality of reagent containers 10, and the soft material 31 covers the first openings 111 of the plurality of reagent containers 10.

Referring to fig. 11-13, in one embodiment, the reagent transfer device further includes a support 80. The supporting member 80 is disposed at the first end 11, and the supporting member 80 is provided with a relief hole 81, the relief hole 81 is disposed opposite to the puncturing position of the puncturing member 40, and the supporting member 80 is configured to support and abut against the first sealing film 20. In this way, in the process of puncturing the first sealing membrane 20 by pressing the puncturing member 40 downwards, the supporting member 80 can support and abut against the first sealing membrane 20, and the avoiding hole 81 which can avoid the puncturing member 40 is formed in the supporting member 80, so that the movement stroke of the puncturing member 40 when the first sealing membrane 20 is punctured is reduced, and the effect of puncturing the first sealing membrane 20 is improved more obviously. Therefore, the sealing film can be conveniently punctured, the possibility that the sealing film is not punctured is greatly reduced, and the puncturing effect of the first sealing film 20 is better.

Referring to fig. 11 to 13, further, a step 112 is disposed on the opening wall of the first opening 111, and the supporting member 80 is disposed on the step 112. Thus, in the production process of the reagent vessel 10, the supporting member 80 is mounted on the step 112, and the first sealing film 20 mounted at the first end 11 positions the supporting member 80, so that the assembling operation of the reagent vessel 10 is convenient. In addition, when the support member 80 is mounted on the step 112, the upper surface of the support member 80 is substantially flush with the end surface of the first end 11, which ensures the sealability of the first sealing film 20 to the first opening 111.

The supporting member 80 is not limited to be disposed on the first end 11 by being mounted on the step 112, but the supporting member 80 may be disposed on the first end 11 by other methods, for example, by being fixed to the first end 11 by mounting members such as screws, pins, rivets, clips, etc., or may be fixed to the first end 11 by being bonded, welded, etc., or the supporting member 80 and the first end 11 may be integrated, and the method is not limited herein and may be disposed according to actual requirements.

Referring to fig. 11 to 13, further, the supporting member 80 is a baffle plate disposed on the step 112, and the avoiding hole 81 is disposed in a middle portion of the baffle plate. In this way, when the pricking member 40 is pressed down to pierce the first sealing film 20, the pricking member generally acts on the middle portion of the first sealing film 20 to achieve a better pricking effect on the first sealing film 20, and accordingly, the avoiding hole 81 is disposed at the middle portion of the baffle plate, so that the avoiding hole 81 can smoothly avoid the pricking member 40. Of course, if the needle-punching member 40 is pushed down to puncture other portions of the first sealing film 20, such as the outer peripheral portion, the relief hole 81 is provided in the outer peripheral portion of the barrier.

In one embodiment, the first end 11 is the top end of the reagent vessel 10 and the second end 12 is the bottom end of the reagent vessel 10. Further, the opening size of the second opening 121 is smaller than the opening size of the first opening 111. Wherein the opening size of the second opening 121 is small, the second sealing membrane 50 on the second opening 121 is easily pierced by the piercing member 72 on the bottom wall of the second chamber, so that it may not be necessary to provide the support member 80 at the first opening 111 similarly to the first end 11. That is, the support member 80 does not need to be disposed on the second end 12, and the support member 80 may be disposed, but is not limited thereto.

Referring to fig. 11 to 13, in one embodiment, the rims 114 of the first ends 11 of at least two reagent vessels 10 are connected to each other. Further, the end faces of the first ends 11 of at least two reagent vessels 10 are in the same plane.

In addition, when there are at least two reagent vessels 10, there are at least two support members 80, and the at least two support members 80 are disposed at the first ends 11 of the at least two reagent vessels 10 in a one-to-one correspondence. In this way, when the at least two pricking members 40 simultaneously press down to prick the first sealing membrane 20, the first sealing membrane 20 at the at least two first openings 111 can be ensured to be pricked by the at least two supporting members 80.

In addition, in this embodiment, the first sealing film 20 is disposed at the first ends 11 of the at least two reagent containers 10 and can simultaneously seal the first openings 111 of the at least two reagent containers 10. In this way, the first sealing film 20 can seal the first openings 111 of at least two reagent containers 10 simultaneously by, for example, thermocompression bonding, and the work efficiency is high without performing a sealing operation on the first openings 111 of the respective reagent containers 10.

Referring to fig. 11 to 13, in one embodiment, the assembling steps of the reagent container 10 include:

the supporting member 80 is first placed on the step 112 on the inner wall of the first opening 111;

then, the first sealing film 20 is fixedly sealed on the end face of the first end 11 by means of hot pressing for example;

then passing the liquid reagent into the second chamber of the reagent vessel 10 through the second end 12 of the reagent vessel 10;

finally, a second sealing film 50 is fixed, for example by heat pressing, to the end face of the second end 12.

Referring again to FIG. 2, in one embodiment, the assembly of the reagent transfer device includes:

firstly, the frame 90 is arranged on the support 70, so that the limiting block 91 of the frame 90 is correspondingly abutted against the support column 73 on the support 70;

the reagent vessel 10 is then mounted in the frame 90 and the cover 30 is placed on the first end 11 of the reagent vessel 10. Specifically, the lid 30 is fixed to the plate edge 114 on which the outer wall of the first end 11 of the reagent vessel 10 is mounted.

It should be noted that the "first flange 113" may be a part of the "first end 11", that is, the "first flange 113" and the "other part of the first end 11" are integrally formed; or a separate member that is separable from the other portions of the first end 11, i.e., the first flange 113 may be manufactured separately and then integrated with the other portions of the first end 11. In one embodiment, as shown in fig. 13, the "first flange 113" is a part of the "first end 11" that is integrally formed.

It should be noted that the "second flange 122" may be "a portion of the second end 12", that is, the "second flange 122" is integrally formed with "the other portion of the second end 12"; or a separate member that is separable from the "other portion of the second end 12", i.e., the "second flange 122" may be manufactured separately and then integrated with the "other portion of the second end 12". As shown in FIG. 13, in one embodiment, the "second flange 122" is a part of the "second end 12" that is integrally formed.

It should be noted that the "third flange 61" may be a "part of the elastic sleeve 60", that is, the "third flange 61" and the "other part of the elastic sleeve 60" are integrally formed; it is also possible to make a separate member, i.e. the third flange 61, which is separable from the rest of the elastic sleeve 60, and then combine it with the rest of the elastic sleeve 60. In one embodiment, as shown in fig. 13, the "third flange 61" is a part of the "elastic sleeve 60" that is integrally formed.

It should be noted that the "support member 80" may be a part of the "reagent container 10", that is, the "support member 80" is integrally formed with the other part of the "reagent container 10"; the "support member 80", which may be a separate member from the "rest of the reagent vessel 10", may be manufactured separately and integrated with the "rest of the reagent vessel 10".

The technical features of the above embodiments can be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the above embodiments are not described, but should be considered as the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above examples only show some embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

In the present invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the second feature or the first and second features may be indirectly contacting each other through intervening media. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.

Claims

1. A reagent transfer device, comprising:

a reagent container having a first end with a first opening communicating with a first chamber of the reagent container;

the first sealing film is arranged at the first end and can seal the first opening;

the cover body covers the first end, and a soft piece which corresponds to the first opening and is not easy to be punctured by a puncturing piece is arranged on the cover body.

2. The reagent transfer device of claim 1, wherein the reagent container is provided with a second end opposite the first end, the second end being provided with a second opening communicating with the first chamber of the reagent container; the reagent container further comprises a second sealing membrane, the second sealing membrane is arranged at the second end and can seal the second opening; the reagent transfer device further comprises a support, a transition cavity is arranged on the support, the transition cavity is provided with an insertion opening corresponding to the second end, the second end passes through the insertion opening and extends into the transition cavity, and a piercing piece used for piercing the second sealing film is arranged on the bottom wall of the transition cavity.

3. The reagent transfer device of claim 2, wherein the first sealing membrane is heat staked to an end face of the first end; the second sealing film is fixed on the end face of the second end in a hot-pressing mode.

4. The reagent transfer device of claim 3, wherein the end face of the first end is provided with a first flange surrounding the first opening, the first sealing membrane being in close abutment with the first flange; the terminal surface of second end is equipped with the encircleing the second open-ended second flange, the second seal membrane with the second flange is closely laminated.

5. The reagent transfer device of claim 2, wherein the outer wall of the second end is provided with at least one third collar around the outer wall, the third collar being in interference fit with the wall of the transition chamber.

6. The reagent transfer device of claim 5, wherein the second end is provided with a groove around the outer wall thereof, and an elastic sleeve is arranged in the groove; the third flange is arranged on the outer wall of the elastic sleeve.

7. The reagent transfer device of claim 2, further comprising a frame; the reagent container is arranged on the frame; the frame is adjustably arranged on the support, and is provided with a first working position and a second working position; when the frame is in the first working position, a space is arranged between the second sealing membrane and the puncture member; when the frame receives external driving force and is greater than preset force, the frame moves from the first working position to the second working position under the action of the external driving force, and the second sealing film is punctured by the puncturing piece when the frame moves to the second working position.

8. The reagent transfer device of claim 7, wherein the support is provided with a support column, the frame is provided with a limit block corresponding to the support column, and the limit block abuts against the support column when the frame is located at the first working position;

9. The reagent transfer device of claim 8, wherein the number of the support columns is at least three, the number of the limiting blocks is at least three, and the three support columns and the three limiting blocks are arranged in a one-to-one correspondence.

10. The reagent transfer device of claim 7, wherein a plate edge is provided on an outer wall of the first end of the reagent container, the frame is provided with an avoiding opening, the reagent container is disposed in the avoiding opening, and the plate edge of the reagent container is lapped on the frame.

11. The reagent transfer device of any one of claims 1 to 10, wherein the number of reagent containers is several, and several of the reagent containers are connected in sequence; the cover body covers the first ends of the reagent containers, and the soft piece covers the first openings of the reagent containers.

12. The reagent transfer device of any one of claims 1 to 10, further comprising a support member disposed at the first end, wherein the support member is provided with an avoiding hole at a position opposite to a piercing position of the piercing member, and the support member is configured to support and abut against the first sealing film.