CN115385046A - Automatic feeding equipment for nucleic acid extraction tube and feeding method thereof - Google Patents
Automatic feeding equipment for nucleic acid extraction tube and feeding method thereof Download PDFInfo
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- CN115385046A CN115385046A CN202211129977.4A CN202211129977A CN115385046A CN 115385046 A CN115385046 A CN 115385046A CN 202211129977 A CN202211129977 A CN 202211129977A CN 115385046 A CN115385046 A CN 115385046A
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- nucleic acid
- material cleaning
- storage table
- extraction tube
- feeding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/02—Devices for feeding articles or materials to conveyors
- B65G47/04—Devices for feeding articles or materials to conveyors for feeding articles
- B65G47/12—Devices for feeding articles or materials to conveyors for feeding articles from disorderly-arranged article piles or from loose assemblages of articles
- B65G47/14—Devices for feeding articles or materials to conveyors for feeding articles from disorderly-arranged article piles or from loose assemblages of articles arranging or orientating the articles by mechanical or pneumatic means during feeding
- B65G47/1407—Devices for feeding articles or materials to conveyors for feeding articles from disorderly-arranged article piles or from loose assemblages of articles arranging or orientating the articles by mechanical or pneumatic means during feeding the articles being fed from a container, e.g. a bowl
- B65G47/1414—Devices for feeding articles or materials to conveyors for feeding articles from disorderly-arranged article piles or from loose assemblages of articles arranging or orientating the articles by mechanical or pneumatic means during feeding the articles being fed from a container, e.g. a bowl by means of movement of at least the whole wall of the container
- B65G47/1421—Vibratory movement
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G29/00—Rotary conveyors, e.g. rotating discs, arms, star-wheels or cones
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
- B65G47/82—Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
- B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
- B65G47/90—Devices for picking-up and depositing articles or materials
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G65/00—Loading or unloading
- B65G65/30—Methods or devices for filling or emptying bunkers, hoppers, tanks, or like containers, of interest apart from their use in particular chemical or physical processes or their application in particular machines, e.g. not covered by a single other subclass
- B65G65/32—Filling devices
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses automatic feeding equipment and a feeding method for a nucleic acid extraction tube. The automatic feeding equipment comprises an extraction tube arranging and transferring mechanism, a station switching mechanism and a rack. The extraction tube arranging and transferring mechanism comprises a front integration component and a detection tube transferring component. The front integration component comprises a vibration disc, a grabbing component and a transverse movement alternating exchange mechanism component. The alternate traversing and exchanging mechanism assembly comprises a traversing base, a cam groove, a synchronous belt, a first roller, a lifting frame, a first storage table, a sliding plate, a linear guide rail and a second storage table and a synchronous wheel. The extracting tube arranging and transferring mechanism can arrange scattered nucleic acid extracting tubes one by one, and send a plurality of nucleic acid extracting tubes to the extracting tube jig of the feeding station at one time, so that the feeding speed is improved, and the influence of the feeding process on the overall operation efficiency of equipment is avoided. In addition, the transverse moving alternative exchange assembly only uses the structure that the synchronous belt is matched with the cam groove to realize the position exchange of the two storage tables without transverse movement.
Description
Technical Field
The invention belongs to the technical field of reagent filling and sealing membranes, and particularly relates to automatic feeding equipment and a feeding method for a nucleic acid extraction tube.
Background
In the prior art, the automatic filling and film sealing equipment of the nucleic acid extraction tubes can realize synchronous operation of a plurality of nucleic acid extraction tubes, and has higher production efficiency; however, the nucleic acid extraction tubes can only be fed one by one in automatic feeding equipment or fed by using a nucleic acid extraction tube queue which is arranged in advance; the efficiency of the mode of material loading one by one is lower, and then can restrict the production efficiency of whole filling line. The nucleic acid extraction tube array which is arranged in advance is used for feeding, manual arrangement needs to be carried out in advance, and high labor cost needs to be consumed.
In addition, the situation that the strip-shaped six-connection-tube nucleic acid extraction tube cannot be accurately positioned during automatic feeding is easy to occur; therefore, it is necessary to perform an auxiliary in-place operation after automatically feeding the nucleic acid extraction tube, and to perform a cleaning operation on the nucleic acid extraction tube in the jig in the case where the nucleic acid extraction tube is not accurately in place.
Disclosure of Invention
The invention aims to provide automatic feeding equipment and a feeding method for a nucleic acid extraction tube.
An automatic feeding device for a nucleic acid extraction tube comprises an extraction tube arranging and transferring mechanism, a station switching mechanism and a rack. The station switching mechanism is arranged on the frame. And a feeding station is arranged on the station switching mechanism. The extracting tube arranging and transferring mechanism comprises a front integration component and a detection tube transferring component. The front integration component comprises a vibrating disk, a grabbing component and a transverse moving alternate component. The vibrating disk is arranged on the frame and used for arranging the output nucleic acid extracting tubes one by one. The grabbing component is used for grabbing the nucleic acid extraction tubes to the transverse moving alternate component one by one to form a row of n detection tube arrays, wherein n is more than or equal to 2.
The cross sliding alternate exchange assembly comprises a cross sliding base, a cam groove, a synchronous belt, a first roller, a lifting frame, a first storage table, a sliding plate, a linear guide rail, a second storage table and a synchronous wheel. The transverse moving base is fixed on the frame. A lifting guide plate is fixed on the transverse moving base; the lifting guide plate is provided with a cam groove. Four synchronizing wheels which are arranged in a rectangular shape in a vertical plane are rotatably connected to the lifting guide plate. The four synchronous wheels are connected through synchronous belt transmission. One of the synchronizing wheels is driven by a motor. The upper and lower groups of linear guide rails are fixed on the transverse moving base.
The second storage table is connected to the linear guide rail located above. The sliding plate is connected on the linear guide rail positioned below in a sliding way. The lifting frame and the sliding plate form a sliding pair which slides along the vertical direction. The bottom of the lifting frame is rotationally connected with a first roller. The first roller is disposed in the cam groove. The top of crane is fixed with first deposit the platform. The first platform of depositing and the second are deposited and all are provided with n and deposit the position on the platform.
The cam groove is in a shape with two high ends and a low middle. When the first roller is positioned at the end part of the cam groove, the first storage table and the second storage table are equal in height. When the first roller is at the lowest position in the middle of the cam groove, the top of the first storage table is lower than the bottom of the second storage table. The sliding plate, the second storage table and the two horizontal sections of the synchronous belt are respectively fixed.
The first storage table and the second storage table are respectively a one-by-one feeding position and an integral transfer position at equal heights; the material loading positions one by one are used for loading the grabbing components; the whole transfer position is used for the detection tube to transfer the assembly to take materials. The detection tube transfer assembly is used for grabbing the n nucleic acid extraction tubes on the first storage table or the second storage table at the integral transfer position to the feeding station at one time.
Preferably, the automatic feeding device for the nucleic acid extracting tube further comprises a flattening and cleaning mechanism. The station switching mechanism is also provided with a flattening and material cleaning station. The flattening and material clearing mechanism comprises a flattening component and a material clearing component. The flattening assembly comprises a flattening cylinder and a pressing plate. The flattening cylinder is fixed with the frame. The end part of a push-out rod of the flattening cylinder is arranged downwards and is fixed with a pressing plate. The pressing plate is positioned right above the flattening and material cleaning station. A cylinder position sensor is arranged on the flattening cylinder; the cylinder position sensor is used for detecting whether the push-out rod of the flattening cylinder reaches a lower limit position.
The material cleaning assembly comprises a jacking material cleaning cylinder, a material cleaning inserting plate, a material cleaning horizontal cylinder, a material cleaning lifting cylinder, a material cleaning hook plate and a waste material groove body. The waste material groove body is fixed on the frame and close to the flattening and material cleaning station. The jacking material cleaning air cylinder is fixed on the frame and is positioned right below the flattening material cleaning station. N clear material picture peg that the clear material cylinder of jacking upwards is fixed with the interval setting in proper order on the ejector pin. The n material cleaning inserting plates can be respectively inserted into n placing position bottom hollow positions of the extracting tube jig at the flattening material cleaning station, and the nucleic acid extracting tube is ejected out of the extracting tube jig.
The material cleaning lifting cylinder is fixed on the flattening cylinder mounting plate; the vertical push-out rod of the material cleaning lifting cylinder is fixed with the cylinder body of the material cleaning horizontal cylinder. The ejector rod of the material clearing horizontal cylinder is fixed with the material clearing hook plate. The bottom surface of the material cleaning hook plate is provided with a hook groove. Under the drive of the material cleaning horizontal cylinder 2-4, the material cleaning hook plate 2-9 can move between the position right above the flattening material cleaning station and the position right above the waste material groove body 2-10. When the material cleaning hook plate 2-9 moves to the position right above the flattening and material cleaning station, the material cleaning hook plate 2-9 can cover all the nucleic acid extraction tubes on the extraction tube jig.
Preferably, the top surface of the material cleaning inserting plate is provided with a V-shaped groove; the moving direction of the piston of the material cleaning horizontal cylinder 2-4 is parallel to the length direction of the V-shaped groove on the top surface of the material cleaning inserting plate 2-3.
Preferably, the extraction tube arranging and transferring mechanism comprises two preposed integration components and a detection tube transferring component. The feeding station of the station switching mechanism and the integral transfer positions in the two front integrated assemblies are on the same straight line. The successive feeding positions in the two pre-integrated modules are located on opposite sides of the corresponding overall transfer position.
Preferably, the detection tube transfer assembly comprises a detection tube moving module and a feeding clamping jaw set. And the tail end mounting block of the detection pipe moving module is provided with a feeding clamping jaw group. The feeding clamping jaw group comprises n mechanical clamping jaws which are arranged in sequence. Six mechanical clamping jaws can be once only with n nucleic acid extraction pipe on first deposit platform or second deposit platform pick up. The detection tube moving module comprises a transverse sliding table and a lifting sliding table. The lifting sliding table is arranged on the sliding block of the transverse sliding table. The moving direction of the sliding block of the transverse sliding table is parallel to a connecting line of the feeding positions of the feeding station and the two front integrated assemblies.
Preferably, the station switching mechanism comprises a turntable, an extraction pipe jig and a driving mechanism. The horizontally arranged rotary table is rotationally connected to the rack and is driven by the driving mechanism to rotate. A plurality of extracting pipe jigs which are uniformly distributed along the circumferential direction of the axis of the rotating disc are arranged on the top surface of the rotating disc.
Preferably, the extraction pipe jig is mounted on a through groove formed in the turntable. N placing positions are arranged on the extraction tube jig; each placing position can be used for placing a nucleic acid extracting tube. The bottoms of the placing positions of the extracting tube jig are all hollowed out. The relative positions of the n placing positions on the extracting tube jig correspond to the relative positions of the n storing positions on the first storing table or the second storing table respectively.
Preferably, a film cutting abdicating groove is arranged between any two adjacent placing positions; the film cutting abdicating groove is arranged on the top surface of the extracting tube jig. Two ends of the film cutting abdicating groove are communicated with two side edges of the top surface of the extraction pipe jig; both ends of the film cutting abdicating groove are provided with leading-in sections with the width gradually increasing from inside to outside.
Preferably, the driving mechanism adopts a motor with a speed reducer.
The automatic feeding method of the automatic feeding equipment for the nucleic acid extraction tube comprises the following steps:
step one, arranging and outputting the nucleic acid extraction tubes which are stacked in a disordered manner by a vibration disc; the grabbing component grabs the nucleic acid extraction tube output by the vibration disc to a first storage table or a second storage table of the horizontal moving alternate component at the feeding positions one by one; when the first storage table or the second storage table at the feeding positions one by one is full and the nucleic acid extraction tube on the first storage table or the second storage table at the integral transfer position is taken away, the synchronous belt moves to drive the first storage table and the second storage table to exchange positions; after the exchange position, the grabbing component continues to grab the nucleic acid extraction tubes one by one at the feeding position.
Step two, the detection tube transfer assembly uniformly grabs the nucleic acid extraction tubes on the first storage table or the second storage table at the integral transfer position to the extraction tube jig at the feeding station.
And step three, rotating the turntable, and transferring the extraction tube jig of the feeding station to a flattening and material cleaning station. The flattening cylinder pushes and presses each nucleic acid extraction tube in the extraction tube jig downwards, so that each nucleic acid extraction tube fully enters the extraction tube jig; if the flattening cylinder cannot reach the lower limit position, the nucleic acid extraction tubes which are not correctly placed are indicated, and the material cleaning assembly removes the nucleic acid extraction tubes from the pushing extraction tube jig.
The removal process is as follows: the material cleaning lifting cylinder and the material cleaning horizontal cylinder drive the material cleaning inserting plate to move to the position right above the flattening material cleaning station. The top end of each nucleic acid extraction tube is pushed to extend into the material hooking groove of the material clearing hook plate by the material clearing inserting plate, and when each nucleic acid extraction tube is pushed to be separated from the extraction tube jig, the material clearing horizontal cylinder drives each nucleic acid extraction tube to move transversely through the material clearing hook plate, and each nucleic acid extraction tube is conveyed into the waste material groove.
The invention has the beneficial effects that:
1. the extracting tube arranging and transferring mechanism can arrange scattered nucleic acid extracting tubes one by one, and send a plurality of nucleic acid extracting tubes to the extracting tube jig of the feeding station at one time, so that the feeding speed is improved, and the influence of the feeding process on the overall operation efficiency of equipment is avoided. In addition, the transverse moving alternate exchange assembly in the extracting tube arranging and transferring mechanism only uses the structure that the synchronous belt is matched with the cam groove to realize the position exchange of the two storage tables under the condition of not carrying out transverse movement, so that the arrangement, stacking and clamping of the detecting tubes can be carried out simultaneously and the feeding can be not influenced mutually.
2. The invention is provided with a flattening and material cleaning mechanism, and judges whether the detection tube is placed in place or not by utilizing the mode that whether a pressing plate can be pressed down in place or not; under the condition that the detection tube is not placed in place, the detection tube is pushed out of the jig by the aid of the hollow structure at the bottom of the insertion plate matched with the jig, and the detection tube is moved out of the waste groove body by the aid of the hook plate, so that operation stability of equipment is improved.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
FIG. 2 is a schematic view of the station switching mechanism of the present invention.
FIG. 3 is a perspective view of the sorting and transferring mechanism for the extracting tube of the present invention.
FIG. 4 is a schematic view of the traverse cross-over interchange assembly of the present invention.
Fig. 5 is a schematic view of a flattening and cleaning mechanism in the invention.
Detailed Description
The invention is further described below with reference to the accompanying drawings.
As shown in figures 1 and 2, the automatic feeding equipment for the nucleic acid extraction tube comprises an extraction tube arranging and transferring mechanism 1, a flattening and material cleaning mechanism 2, a station switching mechanism 3 and a rack 4. The station switching mechanism 3 is fixed on the top of the frame 4. The station switching mechanism 3 has a plurality of stations, including adjacent feeding stations and flattening and cleaning stations. The rest stations are used for matching with the existing filling equipment and film sealing equipment to realize automatic filling and film sealing of the nucleic acid extraction tube. The extraction tube arranging and transferring mechanism 1 is used for arranging scattered nucleic acid extraction tubes into a group of six extraction tube arrays and transferring a group of extraction tubes into an extraction tube jig 9-1 of a feeding station at one time. The flattening and material-clearing mechanism 2 is used for applying downward pressure to each nucleic acid extraction tube in the extraction tube jig 9-1 of the flattening and material-clearing station to ensure that each nucleic acid extraction tube completely enters the extraction tube jig 9-1; when the clamp of the nucleic acid extraction tube occurs, and the flattening and material cleaning mechanism 2 cannot flatten all the nucleic acid extraction tubes, the flattening and material cleaning mechanism 2 automatically cleans all the nucleic acid extraction tubes in the extraction tube jig 9-1.
As shown in FIG. 2, the station switching mechanism 3 comprises a turntable 9-2, an extraction tube jig 9-1 and a driving mechanism. The horizontally arranged rotary table 9-2 is rotatably connected to the frame 4 and is driven by a driving mechanism to rotate. The driving mechanism adopts a motor with a speed reducer. A plurality of extraction pipe jigs 9-1 which are uniformly distributed along the circumferential direction of the axis of the rotary table 9-2 are arranged on the top surface of the rotary table 9-2; the extraction pipe jig 9-1 is arranged on a through groove formed in the rotary table 9-2. The extraction tube jig 9-1 is used for placing the filled nucleic acid extraction tube. The rotation of the rotary table 9-2 can drive each extraction pipe jig 9-1 to sequentially pass through each station. Six placing positions are arranged on the extraction tube jig 9-1; each placing position can be used for placing a nucleic acid extracting tube 5. The nucleic acid isolation tube 5 in this example is specifically a six-tube. The bottoms of the placing positions of the extraction tube jig 9-1 are hollowed out, and the inserting plates of the flattening and material cleaning mechanism 2 can be used for extending into the placing positions from the lower direction to eject the nucleic acid extraction tube 5 out of the placing positions.
A film cutting abdicating groove is arranged between any two adjacent placing positions; the film cutting abdication groove is arranged on the top surface of the extraction pipe jig 9-1. Two ends of the film cutting abdicating groove are communicated with two side edges of the top surface of the extraction pipe jig 9-1; the two ends of the film cutting abdicating groove are provided with leading-in sections with the width gradually increasing from inside to outside. The film cutting abdicating groove is used for positioning and guiding the cutter during film cutting, so that the shapes of the sealed films on the six nucleic acid extraction tubes processed at one time are kept consistent.
As shown in fig. 3, the extraction tube sorting and transferring mechanism 1 includes a front integration component and a detection tube transferring component. The front integration component has two. The two preposed integration components are used for arranging the stacked nucleic acid extracting tubes 5 into a detection tube array of six groups; the detection tube transfer assembly is only one and is used for conveying the detection tube arrays arranged by the two preposed integration assemblies to the extraction tube jig 9-1 of the feeding station.
The front integrated assembly comprises a vibrating disk 1-1, a grabbing assembly 1-2 and a transverse movement alternating assembly 1-3. The vibrating tray 1-1 is installed on the frame and used for arranging and outputting the nucleic acid extracting tubes stacked together one by one. The grabbing component adopts a scara manipulator and is used for grabbing the nucleic acid extracting tubes one by one on the storage table of the transverse moving alternate component 1-3 to form a row of six detecting tube arrays so as to place six nucleic acid extracting tubes on the extracting tube jig 9-1 at a feeding station at one time, and the problems that the time consumption of the feeding step is too long and the overall operation efficiency of the equipment is influenced are avoided.
As shown in figure 4, the transverse moving alternate exchange assembly 1-3 comprises a transverse moving base 1-3-1, a cam groove 1-3-2, a synchronous belt 1-3-3, a first roller 1-3-4, a lifting frame 1-3-5, an alternate guide shaft 1-3-6, a first storage table 1-3-7, a sliding plate 1-3-8, a linear guide rail 1-3-9, a second storage table 1-3-10 and a synchronous wheel 1-3-11. The transverse moving base 1-3-1 is fixed on the frame. A lifting guide plate is fixed on the transverse moving base 1-3-1; the lifting guide plate is provided with a cam groove 1-3-2. Four synchronizing wheels 1-3-11 which are arranged in a rectangular shape in a vertical plane are rotatably connected to the lifting guide plate. The four synchronous wheels 1-3-11 are in transmission connection through synchronous belts 1-3-3. One of the synchronizing wheels 1-3-11 is driven by a motor. The upper and lower groups of linear guide rails 1-3-9 are fixed on the transverse moving base 1-3-1. Each group of linear guide rails 1-3-9 comprises two linear guide rails 1-3-9 which are equal in height and are arranged at intervals.
The second storage table 1-3-10 is slidably connected to the linear guide 1-3-9 located above by means of a slide. The sliding plates 1-3-8 are connected with the linear guide rails 1-3-9 positioned below in a sliding mode through sliding blocks. The lifting frame 1-3-5 and the sliding plate 1-3-8 form a sliding pair sliding along the vertical direction through a linear bearing and an alternate guide shaft 1-3-6. The bottom of the lifting frame 1-3-5 is rotatably connected with a first roller 1-3-4. The first roller 1-3-4 is disposed in the cam groove 1-3-2. The top of the lifting frame 1-3-5 is fixed with a first storage table 1-3-7. Six storage positions are arranged on the first storage table 1-3-7 and the second storage table 1-3-10. The relative position of each storage position corresponds to the relative position of each placing position on the extracting tube jig respectively.
The cam groove 1-3-2 is in a shape with two ends higher and the middle lower. When the first roller 1-3-4 is positioned at the highest position of the end part of the cam groove 1-3-2, the first storage table 1-3-7 and the second storage table 1-3-10 are equal in height. When the first roller 1-3-4 is at the lowest position in the middle of the cam groove 1-3-2, the top of the first storage table 1-3-7 is lower than the bottom of the second storage table 1-3-10, and the first storage table 1-3-7 can pass right below the second storage table 1-3-10.
The sliding plate 1-3-8, the second storage table 1-3-10 and the two horizontal sections of the synchronous belt are respectively fixed. When the synchronous belt moves, the sliding plate 1-3-8 and the second storage table 1-3-10 reversely move at a constant speed to drive the first storage table 1-3-7 and the second storage table 1-3-10 to exchange positions.
The transverse movement alternate exchange component 1-3 is provided with two working positions, namely a one-by-one feeding position and an integral transfer position; the feeding positions one by one are used for feeding the grabbing components 1-2; the whole transfer position is used for taking materials from the detection pipe transfer assembly. The material loading positions are arranged in the moving range of the grabbing component 1-2 one by one; the first storage table 1-3-7 and the second storage table 1-3-10 can be interchanged between the one-by-one feeding position and the integral transfer position, thereby improving the feeding rhythm.
The feeding station of the station switching mechanism 3 and the integral transfer positions of the two front integration assemblies are on the same straight line; therefore, the detection tube transfer assembly can pass through the feeding station of the station switching mechanism 3 and right above the feeding positions in the two preposed integration assemblies through single-degree-of-freedom movement. The successive feeding positions of the two pre-integrated modules are located on opposite sides of the corresponding overall transfer position, so that the two sets of vibrating disks 1-1 and gripping modules 1-2 have a larger installation space.
The detection tube transfer assembly comprises a detection tube moving module and a feeding clamping jaw set 1-5. And a feeding clamping jaw group 1-5 is arranged on the tail end mounting block of the detection pipe moving module. The feeding clamping jaw group 1-5 comprises six mechanical clamping jaws which are arranged in sequence. The mechanical clamping jaws all adopt clamping jaw air cylinders and can grab the nucleic acid extracting tube. The relative positions of the six mechanical clamping jaws correspond to the relative positions of the six storage positions on the first storage table 1-3-7 and the second storage table 1-3-10, so that the six nucleic acid extraction tubes can be clamped at one time.
The detection tube moving module comprises a transverse sliding table 1-4 and a lifting sliding table 1-6. The transverse sliding tables 1-4 and the lifting sliding tables 1-6 are linear electric sliding tables. The lifting sliding table 1-6 is arranged on the sliding block of the transverse sliding table 1-4. The detection tube moving module can drive the feeding clamping jaw set 1-5 to move transversely and move up and down, so that the six nucleic acid extraction tubes are lifted up and transferred to the extraction tube jig 9-1 of the feeding station.
As shown in fig. 5, the flattening and material-clearing mechanism 2 comprises a flattening and material-clearing upright post 2-1, a flattening component, a material-clearing component and a flattening cylinder mounting plate 2-5. The flattening cylinder mounting plate 2-5 is fixed on the frame through the flattening material cleaning upright post 2-1. The flattening assembly comprises a flattening cylinder 2-7 and a pressing plate 2-8. The flattening cylinder 2-7 is fixed on the flattening cylinder mounting plate 2-5. A pressing plate 2-8 is fixed on a downward pushing rod of the flattening cylinder 2-7. The pressing plate 2-8 is positioned right above the flattening and material cleaning station; the pressing plate 2-8 moves downwards to extrude and flatten all the nucleic acid extracting tubes on the extracting tube jig 9-1 of the material cleaning station. The flattening cylinder 2-7 is provided with a cylinder position sensor; the cylinder position sensor is used for detecting whether the push-out rod of the flattening cylinders 2-7 reaches a lower limit position.
The material cleaning component comprises a jacking material cleaning cylinder 2-2, a material cleaning inserting plate 2-3, a material cleaning horizontal cylinder 2-4, a material cleaning lifting cylinder 2-6, a material cleaning hook plate 2-9 and a waste material tank body 2-10. The waste material tank body 2-10 is fixed on the frame and close to the flattening and material cleaning station. The jacking material cleaning cylinder 2-2 is fixed on the frame and is positioned right below the flattening material cleaning station. Six material cleaning inserting plates 2-3 which are sequentially arranged at intervals are fixed on an upward push rod of the jacking material cleaning cylinder 2-2; the relative positions of the six material cleaning inserting plates 2-3 correspond to the relative positions of six placing positions of the extraction pipe jig 9-1. The six material cleaning inserting plates 2-3 can extend upwards into six placing positions of the extracting tube jig 9-1 positioned at the flattening material cleaning station to eject six nucleic acid extracting tubes in the extracting tube jig 9-1. The top surface of the material cleaning inserting plate 2-3 is provided with a V-shaped groove; the length direction of the V-shaped groove is parallel to the length direction of the placing position of the extracting tube jig 9-1. The V-shaped groove can improve the position stability when the nucleic acid extracting tube is ejected.
The material cleaning lifting cylinder 2-6 is fixed on the flattening cylinder mounting plate 2-5; the vertical push-out rod of the material cleaning lifting cylinder 2-6 is fixed with the cylinder body of the material cleaning horizontal cylinder 2-4. A horizontal push-out rod of the material cleaning horizontal cylinder 2-4 is fixed with the edge of one side of the material cleaning hook plate 2-9. The bottom surfaces of the material cleaning hook plates 2-9 are provided with hook grooves. The material cleaning hook plate 2-9 can move between the position right above the flattening and material cleaning station and the position right above the waste material groove body 2-10 under the driving of the material cleaning horizontal cylinder 2-4. The moving direction of the piston of the material cleaning horizontal cylinder 2-4 is parallel to the length direction of the V-shaped groove on the top surface of the material cleaning inserting plate 2-3. The V-shaped groove can provide guidance for the nucleic acid extraction tube when the nucleic acid extraction tube is removed by the material cleaning hook plates 2-9.
When the nucleic acid extraction tubes in the extraction tube jig 9-1 of the flattening and material cleaning station need to be cleaned, the material cleaning lifting cylinder 2-6 and the material cleaning horizontal cylinder 2-4 drive the material cleaning inserting plate to move to the position right above the flattening and material cleaning station. The top end of each nucleic acid extraction tube is pushed to extend into the material hooking groove of the material cleaning hook plate 2-9 by the material cleaning inserting plate, when each nucleic acid extraction tube is pushed to be separated from the extraction tube jig 9-1, the material cleaning horizontal cylinder 2-4 moves transversely, the material cleaning hook plate 2-9 drives each nucleic acid extraction tube to move transversely, and each nucleic acid extraction tube is conveyed into the waste material groove 2-10. Thereby realizing automatic material cleaning when the nucleic acid extracting tube is not correctly placed.
The automatic feeding method of the automatic feeding equipment for the nucleic acid extraction tube specifically comprises the following steps:
step one, a vibration disc 1-1 in the extraction tube arranging and transferring mechanism 1 works to convey the nucleic acid extraction tube 5 to a material position to be extracted. The grasping assembly 1-2 grasps the nucleic acid extracting tube 5 into the first storage stage 1-3-7.
When the six storage positions in the first storage table 1-3-7 are fully filled, the synchronous wheels 1-3-11 rotate under the power of the motors, the first storage table 1-3-7 moves rightwards under the guidance of the linear guide rails 1-3-9, and the second storage table 1-3-10 moves leftwards due to the fact that the synchronous belts are connected with two stations at the same time. Meanwhile, the first roller 1-3-4 pulls the lifting frame 1-3-5 downwards under the guide of the cam groove 1-3-2, and the process is guided by the sliding of the alternate guide shaft 1-3-6 in the sliding plate 1-3-8, so that the first storage table 1-3-7 is stably moved downwards. When the first storage table 1-3-7 is moved to the middle, it is just under the second storage table 1-3-10, so that there is no interference between the two stations. As the first roller 1-3-4 travels to the right side of the cam groove 1-3-2, the first depositing table 1-3-7 starts to ascend until it reaches the normal operation position, by the same principle.
The clamping jaw cylinder 1-6 is opened first, so that the feeding clamping jaw 1-5 is in an open state. Then the material is moved to a second storage table 1-3-10 from the material loading position under the drive of a material loading traverse manipulator 1-4. At this time, the gripper cylinder 1-6 is closed, and the nucleic acid extracting tube 5 is gripped by the feeding gripper 1-5. Then the feeding traversing manipulator 1-4 is lifted to separate the nucleic acid extracting tube 5 from the second storage table 1-3-10. And finally, the feeding transverse moving manipulator 1-4 transversely moves to a feeding position and descends, and the nucleic acid extraction tube 5 is placed into the extraction tube jig 9-1 of the station switching mechanism 3.
And step two, the turntable of the station switching mechanism 3 rotates under the power of a motor, so that the extraction tube jig 9-1 provided with the nucleic acid extraction tube 5 runs a flattening and material cleaning station.
At this time, the flattening cylinders 2 to 7 are pressed downward to flatten the nucleic acid extracting tube 5 which is not put in place, and then raised to the original position. If the flattening cylinder 2-7 reaches the lower limit position (namely, the limit sensor detects a signal) in the process, the nucleic acid extraction tube 5 is flattened to the designated position, and the turntable 9-2 carries the extraction tube jig 9-1 to rotate to the magnetic bead filling station. If the lower limit sensor is not bright, the nucleic acid extraction tube is proved not to be pressed to the designated position, at the moment, the material cleaning lifting cylinder 2-6 extends downwards, and the material cleaning horizontal cylinder 2-4 and the material cleaning hook plate 2-9 arranged on the material cleaning lifting cylinder are descended to the working position. The jacking material cleaning cylinder 2-2 extends upwards to push the nucleic acid extracting tube 5 out of the extracting tube jig 9-1. At the moment, the material cleaning horizontal cylinder 2-4 contracts to drive the material cleaning hook plate 2-9 on the material cleaning horizontal cylinder to hook away the nucleic acid extracting tube 5, and after the nucleic acid extracting tube falls into a specified position, the material cleaning horizontal cylinder 2-4 extends out again, and the material cleaning lifting cylinder 2-6 contracts to enable the material cleaning hook plate 2-9 to return to a standby position.
And step three, rotating a turntable of the station switching mechanism 3 under the power of a motor, so that the extraction tube jig 9-1 provided with the nucleic acid extraction tube 5 is arranged at a subsequent station, and automatic filling, film sealing and blanking are conveniently realized.
Claims (10)
1. An automatic feeding device for a nucleic acid extracting tube comprises a station switching mechanism (3) and a rack (4); the method is characterized in that: the device also comprises an extraction pipe arranging and transferring mechanism (1); the station switching mechanism (3) is arranged on the rack (4); a feeding station is arranged on the station switching mechanism (3); the extraction tube arranging and transferring mechanism (1) comprises a preposed integration component and a detection tube transferring component; the preposed integration component comprises a vibration disc (1-1), a grabbing component (1-2) and a transverse movement alternating interchanging component (1-3); the vibrating disk (1-1) is arranged on the frame and used for arranging the output nucleic acid extracting tubes one by one; the grabbing component is used for grabbing the nucleic acid extraction tubes one by one onto the transverse moving alternate component (1-3) to form a row of n detection tube arrays, wherein n is more than or equal to 2;
the transverse moving alternate interchange assembly (1-3) comprises a transverse moving base (1-3-1), a cam groove (1-3-2), a synchronous belt (1-3-3), a first roller (1-3-4), a lifting frame (1-3-5), a first storage table (1-3-7), a sliding plate (1-3-8), a linear guide rail (1-3-9), a second storage table (1-3-10) and a synchronous wheel (1-3-11); the transverse moving base (1-3-1) is fixed on the rack; a lifting guide plate is fixed on the transverse moving base (1-3-1); the lifting guide plate is provided with a cam groove (1-3-2); four synchronizing wheels (1-3-11) which are arranged in a rectangular shape in a vertical plane are rotatably connected to the lifting guide plate; the four synchronous wheels (1-3-11) are in transmission connection through the synchronous belts (1-3-3); one of the synchronous wheels (1-3-11) is driven by a motor; the upper and lower groups of linear guide rails (1-3-9) are fixed on the transverse moving base (1-3-1);
the second storage table (1-3-10) is connected to the linear guide rail (1-3-9) positioned above; the sliding plate (1-3-8) is connected to the linear guide rail (1-3-9) below in a sliding manner; the lifting frame (1-3-5) and the sliding plate (1-3-8) form a sliding pair which slides along the vertical direction; the bottom of the lifting frame (1-3-5) is rotationally connected with a first roller (1-3-4); the first roller (1-3-4) is arranged in the cam groove (1-3-2); a first storage table (1-3-7) is fixed at the top of the lifting frame (1-3-5); the first storage table (1-3-7) and the second storage table (1-3-10) are respectively provided with n storage positions;
the cam groove (1-3-2) is in a shape with two high ends and a low middle part; when the first roller (1-3-4) is positioned at the end part of the cam groove (1-3-2), the first storage table (1-3-7) and the second storage table (1-3-10) are equal in height; when the first roller (1-3-4) is at the lowest position in the middle of the cam groove (1-3-2), the top of the first storage table (1-3-7) is lower than the bottom of the second storage table (1-3-10); the sliding plate (1-3-8), the second storage table (1-3-10) and the two horizontal sections of the synchronous belt are respectively fixed;
the two positions of the first storage table (1-3-7) and the second storage table (1-3-10) which are equal in height are respectively a one-by-one feeding position and an integral transfer position; the feeding positions one by one are used for feeding the grabbing components (1-2); the integral transfer position is used for the detection tube transfer assembly to take materials; the detection tube transfer assembly is used for grabbing the n nucleic acid extraction tubes on the first storage table (1-3-7) or the second storage table (1-3-10) at the integral transfer position to the feeding station at one time.
2. The automatic loading equipment for the nucleic acid extraction tube according to claim 1, wherein: the device also comprises a flattening and material clearing mechanism (2); a flattening and material cleaning station is also arranged on the station switching mechanism (3); the flattening and material clearing mechanism (2) comprises a flattening component and a material clearing component; the flattening assembly comprises a flattening cylinder (2-7) and a pressing plate (2-8); the flattening cylinders (2-7) are fixed with the frame; the end part of a push-out rod of the flattening cylinder (2-7) is arranged downwards, and a pressing plate (2-8) is fixed; the pressing plate (2-8) is positioned right above the flattening and material cleaning station; a cylinder position sensor is arranged on the flattening cylinder (2-7); the cylinder position sensor is used for detecting whether a push-out rod of the flattening cylinder (2-7) reaches a lower limit position;
the material cleaning component comprises a jacking material cleaning cylinder (2-2), a material cleaning inserting plate (2-3), a material cleaning horizontal cylinder (2-4), a material cleaning lifting cylinder (2-6), a material cleaning hook plate (2-9) and a waste material tank body (2-10); the waste material tank body (2-10) is fixed on the frame and is close to the flattening and material cleaning station; the jacking material cleaning cylinder (2-2) is fixed on the frame and is positioned right below the flattening material cleaning station; n material cleaning inserting plates (2-3) which are sequentially arranged at intervals are fixed on an upward push rod of the jacking material cleaning cylinder (2-2); the n material cleaning inserting plates (2-3) can be respectively inserted into the bottom hollow positions of n placing positions of the extraction tube jig (9-1) at the flattening material cleaning station, and the nucleic acid extraction tube is ejected out of the extraction tube jig (9-1);
the material cleaning lifting cylinder (2-6) is fixed on the flattening cylinder mounting plate (2-5); a vertical push-out rod of the material cleaning lifting cylinder (2-6) is fixed with a cylinder body of the material cleaning horizontal cylinder (2-4); a push-out rod of the material cleaning horizontal cylinder (2-4) is fixed with the material cleaning hook plate (2-9); the bottom surface of the material cleaning hook plate (2-9) is provided with a hook groove; under the driving of the material cleaning horizontal cylinder 2-4, the material cleaning hook plate 2-9 can move between the position right above the flattening material cleaning station and the position right above the waste material groove body 2-10; when the material cleaning hook plate 2-9 moves to the position right above the flattening and material cleaning station, the material cleaning hook plate 2-9 can cover all the nucleic acid extraction tubes on the extraction tube jig (9-1).
3. The automatic loading equipment for the nucleic acid extraction tube according to claim 2, wherein: the top surface of the material cleaning inserting plate (2-3) is provided with a V-shaped groove; the moving direction of the piston of the material cleaning horizontal cylinder 2-4 is parallel to the length direction of the V-shaped groove on the top surface of the material cleaning inserting plate 2-3.
4. The automatic loading apparatus for nucleic acid extraction tubes according to claim 1, 2 or 3, wherein: the extraction tube sorting and transferring mechanism (1) comprises two preposed integration components and a detection tube transferring component; the feeding station of the station switching mechanism (3) and the integral transfer positions of the two front integrated assemblies are on the same straight line; the successive feeding positions in the two pre-integrated modules are located on opposite sides of the corresponding overall transfer position.
5. The automatic nucleic acid extraction tube feeding apparatus according to claim 1, 2 or 3, wherein: the detection tube transfer assembly comprises a detection tube moving module and a feeding clamping jaw group (1-5); a feeding clamping jaw set (1-5) is arranged on the tail end mounting block of the detection pipe moving module; the feeding clamping jaw group (1-5) comprises n mechanical clamping jaws which are sequentially arranged; the six mechanical clamping jaws can clamp the n nucleic acid extraction tubes on the first storage table (1-3-7) or the second storage table (1-3-10) at one time; the detection tube moving module comprises a transverse sliding table (1-4) and a lifting sliding table (1-6); the lifting sliding table (1-6) is arranged on a sliding block of the transverse sliding table (1-4); the moving direction of the sliding blocks of the transverse sliding table (1-4) is parallel to the connecting line of the feeding positions in the feeding station and the two front integrated assemblies.
6. The automatic loading apparatus for nucleic acid extraction tubes according to claim 1, 2 or 3, wherein: the station switching mechanism (3) comprises a turntable (9-2), an extraction tube jig (9-1) and a driving mechanism; the horizontally arranged rotary table (9-2) is rotationally connected to the rack (4) and is driven by the driving mechanism to rotate; a plurality of extracting pipe jigs (9-1) which are uniformly distributed along the circumferential direction of the axis of the rotating disc (9-2) are arranged on the top surface of the rotating disc.
7. The automatic loading equipment for the nucleic acid extraction tube according to claim 6, wherein: the extraction pipe jig (9-1) is arranged on a through groove formed in the rotary table (9-2); n placing positions are arranged on the extraction tube jig (9-1); each placing position can be used for placing a nucleic acid extracting tube (5); the bottoms of the placing positions of the extraction tube jig (9-1) are hollowed; the relative positions of the n placing positions on the extraction tube jig (9-1) correspond to the relative positions of the n placing positions on the first storage table (1-3-7) or the second storage table (1-3-10) respectively.
8. The automatic loading equipment for the nucleic acid extraction tube according to claim 7, wherein: a film cutting abdicating groove is arranged between any two adjacent placing positions; the film cutting abdicating groove is arranged on the top surface of the extraction pipe jig (9-1); two ends of the film cutting abdicating groove are communicated with the edges of two sides of the top surface of the extraction pipe jig (9-1); the two ends of the film cutting abdicating groove are provided with leading-in sections with the width gradually increasing from inside to outside.
9. The automatic loading equipment for the nucleic acid extraction tube according to claim 6, wherein: the driving mechanism adopts a motor with a speed reducer.
10. The automatic feeding method of the automatic feeding apparatus for nucleic acid extracting tubes according to claim 2, wherein: the method comprises the following steps:
step one, arranging and outputting nucleic acid extraction tubes which are stacked in a disordered manner in sequence by a vibration disc (1-1); the grabbing component (1-2) grabs the nucleic acid extracting tube output by the vibrating disk (1-1) to a first storage table (1-3-7) or a second storage table (1-3-10) of the horizontal moving alternate component (1-3) at the feeding position one by one; when the first storage table (1-3-7) or the second storage table (1-3-10) at the loading positions one by one is full and the nucleic acid extraction tube on the first storage table (1-3-7) or the second storage table (1-3-10) at the integral transfer position is removed, the synchronous belt moves to drive the first storage table (1-3-7) and the second storage table (1-3-10) to exchange positions; after the exchange positions, the grabbing component (1-2) continues to grab the nucleic acid extraction tubes one by one at the feeding position;
step two, the detection tube transfer assembly uniformly grabs the nucleic acid extraction tubes on the first storage table (1-3-7) or the second storage table (1-3-10) at the integral transfer position to an extraction tube jig at a feeding station;
rotating the turntable, and transferring the extraction tube jig of the feeding station to a flattening and material cleaning station; the flattening cylinder (2-7) pushes and presses each nucleic acid extraction tube in the extraction tube jig downwards, so that each nucleic acid extraction tube fully enters the extraction tube jig; if the flattening cylinders (2-7) cannot reach the lower limit position, the nucleic acid extraction tubes which are not correctly placed exist, and the material cleaning assembly removes the nucleic acid extraction tubes from the pushing extraction tube jig;
the removing process comprises the following steps: the material cleaning lifting cylinder (2-6) and the material cleaning horizontal cylinder (2-4) drive the material cleaning inserting plate to move to the position right above the flattening and material cleaning stations; the top end of each nucleic acid extraction tube is pushed to extend into the material hooking groove of the material cleaning hook plate (2-9) by the material cleaning inserting plate, and when each nucleic acid extraction tube is pushed to be separated from the extraction tube jig (9-1), the material cleaning horizontal cylinder (2-4) drives each nucleic acid extraction tube to move transversely through the material cleaning hook plate (2-9), and each nucleic acid extraction tube is conveyed into the waste material groove body (2-10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211129977.4A CN115385046A (en) | 2022-09-16 | 2022-09-16 | Automatic feeding equipment for nucleic acid extraction tube and feeding method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211129977.4A CN115385046A (en) | 2022-09-16 | 2022-09-16 | Automatic feeding equipment for nucleic acid extraction tube and feeding method thereof |
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| CN115385046A true CN115385046A (en) | 2022-11-25 |
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| CN202211129977.4A Pending CN115385046A (en) | 2022-09-16 | 2022-09-16 | Automatic feeding equipment for nucleic acid extraction tube and feeding method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117179052A (en) * | 2023-09-21 | 2023-12-08 | 日照长荣生物科技有限公司 | Freeze-dried infant yoghurt dissolved bean manufacturing method and forming equipment |
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- 2022-09-16 CN CN202211129977.4A patent/CN115385046A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117179052A (en) * | 2023-09-21 | 2023-12-08 | 日照长荣生物科技有限公司 | Freeze-dried infant yoghurt dissolved bean manufacturing method and forming equipment |
| CN117179052B (en) * | 2023-09-21 | 2024-06-07 | 日照长荣生物科技有限公司 | Freeze-dried infant yoghurt dissolved bean manufacturing method and forming equipment |
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