CN115282105A - Infant Tong Hufu composition and preparation method thereof - Google Patents

Infant Tong Hufu composition and preparation method thereof Download PDF

Info

Publication number
CN115282105A
CN115282105A CN202210969713.3A CN202210969713A CN115282105A CN 115282105 A CN115282105 A CN 115282105A CN 202210969713 A CN202210969713 A CN 202210969713A CN 115282105 A CN115282105 A CN 115282105A
Authority
CN
China
Prior art keywords
parts
skin
composition
hufu
tong
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202210969713.3A
Other languages
Chinese (zh)
Inventor
陈伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202210969713.3A priority Critical patent/CN115282105A/en
Publication of CN115282105A publication Critical patent/CN115282105A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706Algae
    • A61K8/9711Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides an infant Tong Hufu composition and a preparation method thereof, and relates to the technical field of skin care products. An infant Tong Hufu composition comprising, in parts by weight: 0.01-0.1 part of hyaluronic acid, 0.1-0.8 part of ceramide, 1-5 parts of amino acid, 1-5 parts of cholesterol, 5-15 parts of jojoba oil, 5-15 parts of sea buckthorn oil, 1-5 parts of squalane, 0.01-0.08 part of turmeric extract, 3-9 parts of aloe barbadensis extract, 1-10 parts of fucus extract, 2-12 parts of cucumber extract, 0.1-0.9 part of thickening agent and 100-150 parts of deionized water. The infant Tong Hufu composition has a strong moisturizing function, can increase the thickness of a cutin layer, effectively repairs skin barrier damage and keeps skin healthy. The preparation method can fully mix the components, so that the obtained composition has good uniformity, the composition has better repairing effect on skin barriers, and the protective capability of the skin is improved.

Description

Infant Tong Hufu composition and preparation method thereof
Technical Field
The invention relates to the technical field of skin care products, and particularly relates to an infant Tong Hufu composition and a preparation method thereof.
Background
The skin is the largest organ of the human body, and the barrier of the skin is the first line of defense of the human body. In the field of cosmetics, many products with whitening effect make skin tender by removing horny layer, which is an important barrier of skin and plays an important role in keeping skin healthy.
Skin thickness of infants is far less than that of adults, natural barriers of the skin are not completely developed, and skin cuticles of the infants are easily damaged in severe environments such as cold, dryness, sand dust and the like, so that deeper damage is caused to the skin. If there is a lack of skin barrier protection, contaminants in the air and contaminants on items that the skin contacts are prone to enter the skin, causing more serious health problems such as inflammation.
In addition, because the ability of oil secretion of babies is not strong, when the skin barrier is damaged, the skin barrier is difficult to repair by the babies, so that the skin care product which is specially used for babies and repairs the skin barrier has important significance.
Disclosure of Invention
The invention aims to provide an infant Tong Hufu composition which has a strong moisturizing function, can increase the thickness of a cutin layer, effectively repairs skin barrier damage and keeps skin healthy.
The invention also aims to provide a preparation method of the infant Tong Hufu composition, which can fully mix the components, so that the obtained composition has good uniformity, the composition has better repair effect on skin barriers, and the protection capability of the skin is improved.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
The invention provides an infant Tong Hufu composition which comprises the following components in parts by weight: 0.01-0.1 part of hyaluronic acid, 0.1-0.8 part of ceramide, 1-5 parts of amino acid, 1-5 parts of cholesterol, 5-15 parts of jojoba oil, 5-15 parts of sea buckthorn oil, 1-5 parts of squalane, 0.1-1.5 parts of turmeric extract, 3-9 parts of aloe barbadensis extract, 1-10 parts of fucus extract, 2-12 parts of cucumber extract, 0.1-0.9 part of thickening agent and 100-150 parts of deionized water.
The invention provides a preparation method of an infant Tong Hufu composition, which comprises the following steps:
mixing cholesterol, thickener, jojoba oil, oleum Hippophae and squalane, heating and maintaining temperature to obtain oil phase mixture; mixing hyaluronic acid, ceramide and amino acid, adding deionized water, heating and preserving heat to obtain a water phase mixture; adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, and vacuum emulsifying.
The embodiment of the invention at least has the following beneficial effects:
in the invention, the similar skin structure is reproduced by the components of hyaluronic acid, ceramide, cholesterol and squalane, the water evaporation is inhibited and the inflammatory reaction is relieved by increasing the thickness of the horny layer of the skin, and the skin barrier is enhanced and toughened for sensitive and tender skin. The skin barrier repairing and protecting effects of the composition on skin are further improved by combining with other components, and the functions of moisturizing, promoting osmosis, improving skin immunity, regulating skin metabolism, promoting blood circulation, regulating skin grease secretion, supplementing skin nutrient components, inhibiting bacteria, resisting inflammation and the like are realized, so that the resistance of the skin of the infants to relief is improved, and the skin health is maintained. And the components are reasonable in proportion, so that the components have better synergistic promotion effect, the water replenishing and locking effect can be obviously enhanced, the skin barrier can be prevented from being damaged, and the damaged skin barrier can be repaired.
According to the invention, the components are mixed and combined according to the properties of the components, so that the dispersion degree of each component in the composition is better, the components can play a role, and the permeation of each component to the skin can be enhanced, so that the skin absorption is enhanced, and the repair effect on the skin barrier is promoted.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
An infant Tong Hufu composition comprises the following components in parts by weight: 0.01-0.1 part of hyaluronic acid, 0.1-0.8 part of ceramide, 1-5 parts of amino acid, 1-5 parts of cholesterol, 5-15 parts of jojoba oil, 5-15 parts of sea buckthorn oil, 1-5 parts of squalane, 0.01-0.08 part of turmeric extract, 3-9 parts of aloe barbadensis extract, 1-10 parts of fucus extract, 2-12 parts of cucumber extract and 0.1-0.9 part of thickening agent.
The skin barrier is composed of a sebaceous membrane, which is a layer of oil secreted by the skin and covering the skin surface, and the stratum corneum, which maintains the health of the skin. The horny layer is a 'brick wall structure', and the horny cells are combined with intercellular substances to form a stable barrier, so that the skin is prevented from being damaged by external harmful factors, excessive water loss is avoided, and the smooth and moist appearance of the skin is maintained. The stratum corneum is constantly in dynamic balance of desquamation and migration, and the health of the skin can be guaranteed only if the stratum corneum normally and healthily falls off.
Hyaluronic acid, also known as hyaluronic acid, has the formula (C) 14 H 21 NO 11 ) n Is a disaccharide glycosaminoglycan composed of D-glucuronic acid and N-acetylglucosamine. Hyaluronic acid is an important component constituting human intercellular substance, and can exert physiological functions of retaining water, maintaining extracellular space, and regulating osmotic pressure. The hyaluronic acid contains a large amount of carboxyl and hydroxyl, so that a large amount of water can be combined to play a stable water retention role, and the hyaluronic acid is polymerized among molecules to form a complex network structure, so that the hyaluronic acid has better elasticityAnd thus can serve as a good skin protection barrier. Besides, hyaluronic acid has the functions of regulating inflammatory factors, promoting the growth, differentiation and reconstruction of cells, promoting the proliferation and differentiation of cells, scavenging free radicals and the like. The hyaluronic acid can effectively improve the skin nutrition metabolism, make the skin tender and smooth, increase the elasticity and prevent aging; water is locked strongly, the fiber structure is perfected, and blood circulation is enhanced; increase the skin tightness, shrink pores and enable the skin to be tight and elastic.
Ceramide, namely, after the skin is damaged in a barrier, the lipid synthesis of the horny layer is reduced, the ceramide content in the horny layer is reduced, ceramide can be used for directly supplementing ceramide lost in the horny layer of the skin, so that the ceramide content in the horny layer of the skin is increased, and meanwhile, the ceramide can be used for increasing the thickness of the horny layer of the skin and improving the water holding capacity of the skin. Secondly, ceramide has a strong ability to associate water molecules, maintains the moisture of the skin through a network structure formed in the stratum corneum, has a strong moisturizing effect on the skin, and is further beneficial to repair of the skin barrier. Moreover, ceramides inhibit the production of inflammatory factors, thereby inhibiting inflammatory reactions and alleviating skin discomfort associated with the stimulation of sensitive muscles.
The amino acid is in a small molecular structure, is easy to be absorbed by a human body, can help other components to better permeate into the skin, can improve the functions of moisturizing, can accelerate the repair of skin barriers, and improves the resistance of the skin. The amino acid can improve the skin immunologic function, regulate water, acid and alkali, balance grease, improve the anti-allergy capability of sensitive skin and prevent wrinkles; activating the activity of superoxide dismutase peroxide of skin cells, removing excessive free radicals of the skin cells and effectively delaying skin aging; activating phagocytic function of macrophage, strengthening the functions of detoxification and detoxification of lymphatic system, effectively blocking the invasion of external harmful substances to skin, improving the anti-allergic capability of skin, and decomposing and excreting harmful substances and aged cells in vivo; can generate chelation reaction with divalent metal ions in the bran, prevent excessive divalent metal ions from generating crosslinking action with collagen in the skin, maintain enough collagen fibers and elastic fibers, and make the skin soft, fine and elastic. The skin care product can help activate cells, promote metabolism of skin and blood circulation, effectively moisturize and replenish water for the skin, improve the skin function anti-allergic capability, help the skin resist wrinkles, maintain enough collagen fibers and elastic fibers, and make the skin smooth, fine and elastic.
Cholesterol, also known as cholesterol, is contained in the secretions of the human skin in a certain amount and has a smoothing and maintenance effect. Cholesterol has high permeability to skin, and can maintain skin surface moisture, promote skin metabolism, and inhibit skin inflammation; can be used as W/O type emulsifier for producing cream, and has the advantages of good use feeling (good auxiliary spreading property, smoothness, non-stick), good durability, and no deterioration.
The jojoba oil has the effect of regulating moisture of skin, is easily absorbed by the skin, and can enhance the skin moisture barrier; can regulate the secretion of skin oil, is beneficial to cleaning pores and preventing skin from being blocked; contains abundant vitamin D and protein, is a good moisturizing and moisture-preserving oil, can effectively increase the skin elasticity, and reduces the generation of dry wrinkles and fine wrinkles.
The seabuckthorn oil contains amino acid, multiple vitamins, trace elements, unsaturated fatty acid, flavone and the like, and the flavone has a certain antioxidation effect and can eliminate free radicals of skin cells to obtain the effect of relieving aging; contains a large amount of vitamin C, can inhibit the growth of melanin in vivo, and can make skin white, tender and smooth; the skin care product can also inhibit skin tissue inflammation, enhance the anti-inflammatory effect of skin, help damaged skin tissue to heal quickly, promote skin tissue regeneration, improve skin metabolism, repair damaged skin, prevent skin from being invaded by bacteria and prevent skin from being damaged. In addition, the seabuckthorn oil can provide nutrient components for the skin and has the effects of comprehensively nourishing, protecting and repairing the skin.
Squalane is a component existing in skin, is very mild, is not sensitized, has particularly good skin-friendly property and permeability, can be highly compatible with sebum secreted by the skin, forms a breathable protective film on the surface layer of the skin, and plays a role in moisturizing and moistening the skin; can also permeate into skin to supplement cell lipid, promote repair of aged and damaged cells, enhance skin regeneration ability, and maintain skin elasticity and plumpness. Squalane can also inhibit peroxidation of skin lipid, can effectively permeate into skin, can promote proliferation of skin basal cells, and has obvious physiological effects of delaying skin aging, and improving and eliminating chloasma. Squalane can also open pores, promote blood microcirculation, promote cell metabolism, and help repair damaged cells.
Turmeric extract can reduce skin inflammation and help heal damaged skin barriers; is rich in antioxidant, and can protect skin from further damage; has antibacterial effect, and helps to kill bacteria and protect skin from infection and acne. In addition, the turmeric extract has an inhibiting effect on cerebral amidase, so that the content of cerebral amidase in the cortex is maintained, and the skin can be softened; it has elastase inhibiting and water holding effects, and can be used for conditioning skin.
The aloe vera extract can form a thin breathable film on the surface layer of the skin while permeating the skin, so as to prevent the evaporation of skin moisture, and polysaccharide components and amino acid substances after permeating the skin have very obvious effects of moisturizing, moistening and softening, so that the adsorbability and the hydration of the horny layer are enhanced, the skin losing elasticity and the dry horny layer rapidly achieve the effects of activation and water filling, and the original smoothness, softness and good elasticity of the skin are recovered. The natural anthraquinone glycoside in Aloe is natural whitening sunscreen component, can effectively prevent ultraviolet from stimulating activity of tyrosinase, prevent melanin generation and pigmentation, and has effects of brightening skin, removing yellow gas and whitening skin. The aloe contains amino acids and vitamins which cannot be synthesized by human bodies, can effectively stabilize melanin active enzyme, decompose and inhibit the activity of the enzyme, promote the formed melanin to be quickly decomposed and metabolized, prevent the melanin from being formed again, and achieve the effects of whitening and spot lightening. Aloe polysaccharide can improve superoxide dismutase activity, and has effects of scavenging free radicals, preventing cell aging, and treating chronic allergy; and can accelerate cell division and activate, rapidly permeate into the basal layer of human skin, promote skin cell activation, delay cell aging, and recover skin elasticity and firmness. Aloe polypeptide and amino acids have antiinflammatory, analgesic, and skin wound repairing effects, and can be used for treating skin inflammation. The natural mucopolysaccharide has the effects of absorbing and isolating ultraviolet rays, the aloe polysaccharide has the function of repairing after sunburn, and the aloe polysaccharide can promote the growth of tissue cortical fibers, provide cell nutrients, help cell repair, promote cell metabolism and effectively repair sunburned skin. The natural aloe polypeptide can enhance the resistance of human skin, deeply clean the skin and inhibit the growth of bacteria; can quickly repair damaged skin cells, dredge and block pores, effectively remove acnes and repair acne marks. Aloe tincture is a substance with strong antibacterial property, and can kill fungi, bacteria, virus, etc., and inhibit and eliminate development and reproduction of pathogen.
The glutamic acid contained in the fucus extract can improve the softness and smoothness of the skin, effectively nourish the skin, provide a sebaceous membrane for the skin, protect the skin and help the metabolism of fat cells and the regeneration of connective tissues; contains minerals, vitamins and polyphenols, and can stimulate the natural healing process of the body. It can also provide nutrients required for healthy cell growth and normal metabolism; protecting skin cell mitochondria, thereby maintaining normal functions of mitochondria and normal metabolism of cells.
The cucumber extract has the function of moisturizing, can bring water to the horny layer, and can well achieve the function of moisturizing the horny layer.
The thickening agent is xanthan gum which can supplement water for skin and prevent water loss, has good thickening effect and can improve the viscosity of a material system so that the material system can keep a uniform and stable suspension state or an opacified state or form gel.
In the embodiment, the skin care composition for babies comprises the following components in parts by weight: 0.05 part of hyaluronic acid, 0.5 part of ceramide, 2 parts of amino acid, 3 parts of cholesterol, 8 parts of jojoba oil, 7 parts of sea buckthorn oil, 2 parts of squalane, 1 part of turmeric extract, 5 parts of aloe barbadensis extract, 5 parts of fucus extract, 10 parts of cucumber extract, 0.2 part of thickener and 130 parts of deionized water. The components are reasonable in proportion, the mutual synergistic promotion effect among the components is better, the water replenishing and locking effect can be obviously enhanced, the skin barrier can be prevented from being damaged, and the damaged skin barrier can be repaired.
In this example, the infant Tong Hufu composition further comprises, by weight, 0.01-0.08 parts panthenol and 0.1-1.2 parts lecithin.
Panthenol, also known as vitamin B5, is a water-soluble, stable, small molecule that readily penetrates the stratum corneum, and is useful for increasing skin permeability, moisturizing and hydrating the stratum corneum, and associated improvement in skin roughness, skin exfoliation, and skin elasticity, protecting the skin from irritation and damage due to SLS; has effects in improving skin barrier, relieving inflammation, relieving itching and tranquilizing mind.
Lecithin is an indispensable substance for human cells, and if it is lacking, it reduces the ability of skin cells to regenerate, resulting in rough skin, wrinkles, etc. Lecithin has moisturizing and antioxidant effects, and can ensure skin regeneration activity, and the component has good hydrophilicity and lipophilicity, and can increase skin luster after use. The lecithin has the double characteristics of polarity and non-polarity, can help nutrient substances and metabolic wastes to smoothly pass through cell membranes and promote the exchange of substances inside and outside cells; has effects in promoting skin metabolism, promoting absorption of fat-soluble vitamins, and improving skin water retention and glossiness.
In this example, the infant Tong Hufu composition further comprises 0.01-0.4 parts by weight oat β -glucan.
The oat beta-glucan can activate immune cells, so that cells in skin tissues are gathered to specific parts, the immune response of the immune cells to external stimulation is improved, the harm of ultraviolet rays to the skin cells is reduced, and the skin is protected; promoting collagen synthesis, and helping to maintain skin elasticity; improving skin blood circulation, promoting blood circulation and skin metabolism, improving skin texture, and maintaining normal skin barrier function.
A method for preparing an infant Tong Hufu composition, comprising the steps of:
mixing cholesterol, thickener, jojoba oil, oleum Hippophae and squalane, heating to 80-95 deg.C, maintaining for 10-20min at a heating rate of 1-3 deg.C/min to obtain oil phase mixture; mixing hyaluronic acid, ceramide and amino acid, adding deionized water, heating to 80-95 deg.C, maintaining the temperature for 10-20min at a heating rate of 1-3 deg.C/min to obtain water phase mixture; adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, vacuum emulsifying, emulsifying at 30-50MPa for 5-15min at 2000-3000r/min, cooling to 30-40 deg.C, and aging for 5-10 hr.
The components are mixed and combined according to the properties of the components, so that the dispersion degree of each component in the composition is better, the components can play a role, and the permeation of each component to the skin can be enhanced, so that the skin absorption is enhanced, and the repair effect on the skin barrier is promoted. Different components are heated and insulated respectively, so that the components can be fully mixed according to the viscosity of the components, and the uniformity of the components in the mixture is improved. In the vacuum emulsification, surface active substances such as lecithin and cholesterol are associated with each other to form a dense monolayer, and water is contained therein. A large amount of associations are uniformly dispersed in oil to form the water-in-oil composition, so that the composition has better skin permeation effect and can remarkably improve the capability of repairing skin barriers.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
A method for preparing an infant Tong Hufu composition, comprising the steps of:
the components are as follows: 0.01g hyaluronic acid, 0.1g ceramide, 1g amino acid, 1g cholesterol, 5g jojoba oil, 5g sea buckthorn oil, 1g squalane, 0.01g turmeric extract, 3g aloe barbadensis extract, 1g fucus extract, 2g cucumber extract, 0.1g xanthan gum, and 100g deionized water.
Mixing cholesterol, xanthan gum, jojoba oil, oleum Hippophae and squalane, heating to 80 deg.C, maintaining the temperature for 10min at a heating rate of 1 deg.C/min to obtain oil phase mixture;
mixing hyaluronic acid, ceramide and amino acid, adding deionized water, heating to 80 deg.C, maintaining the temperature for 10min at a heating rate of 1 deg.C/min to obtain water phase mixture;
adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, vacuum emulsifying, emulsifying at 30MPa for 5min at 2000r/min, cooling to 30 deg.C, and aging for 5 hr.
Example 2
A method for preparing an infant Tong Hufu composition, comprising the steps of:
the components are as follows: 0.05g hyaluronic acid, 0.5g ceramide, 2g amino acid, 3g cholesterol, 8g jojoba oil, 7g sea buckthorn oil, 2g squalane, 1g turmeric extract, 5g aloe barbadensis extract, 5g fucus extract, 10g cucumber extract, 0.2g thickener and 130g deionized water.
Mixing cholesterol, xanthan gum, jojoba oil, oleum Hippophae and squalane, heating to 90 deg.C, maintaining the temperature for 15min at a heating rate of 2 deg.C/min to obtain oil phase mixture;
mixing hyaluronic acid, ceramide and amino acid, adding deionized water, heating to 85 deg.C, maintaining the temperature for 12min at a heating rate of 2 deg.C/min to obtain water phase mixture;
adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, vacuum emulsifying at 40MPa for 10min at 2500r/min, cooling to 35 deg.C, and aging for 5-10 hr.
Example 3
A method for preparing an infant Tong Hufu composition, comprising the steps of:
the components are as follows: 0.1g hyaluronic acid, 0.8g ceramide, 5g amino acid, 5g cholesterol, 15g jojoba oil, 15g sea buckthorn oil, 5g squalane, 0.08g turmeric extract, 9g aloe barbadensis extract, 10g fucus extract, 12g cucumber extract, 0.9g xanthan gum, 150g deionized water, 0.08g panthenol and 1.2g lecithin.
Mixing cholesterol, xanthan gum, jojoba oil, oleum Hippophae and squalane, heating to 95 deg.C, maintaining the temperature for 20min at a heating rate of 3 deg.C/min to obtain oil phase mixture;
mixing hyaluronic acid, ceramide and amino acid, adding deionized water, heating to 95 deg.C, maintaining the temperature for 20min at a heating rate of 3 deg.C/min to obtain water phase mixture;
adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, vacuum emulsifying at 50MPa for 15min at 3000r/min, cooling to 40 deg.C, and aging for 10 hr.
Example 4
A method for preparing an infant Tong Hufu composition, comprising the steps of:
the components are as follows: 0.08g hyaluronic acid, 0.4g ceramide, 4g amino acid, 3g cholesterol, 8g jojoba oil, 12g sea buckthorn oil, 4g squalane, 0.02g turmeric extract, 4g aloe barbadensis extract, 8g fucus extract, 6g cucumber extract, 0.2g xanthan gum, 140g deionized water, 0.03g panthenol, 0.5g lecithin and 0.08g oat.
Mixing cholesterol, xanthan gum, jojoba oil, oleum Hippophae and squalane, heating to 95 deg.C, maintaining for 18min at a heating rate of 1.5 deg.C/min to obtain oil phase mixture;
mixing hyaluronic acid, ceramide, panthenol, lecithin, oat beta-glucan and amino acid, adding deionized water, heating to 82 deg.C, keeping the temperature for 14min, and heating at a rate of 1 deg.C/min to obtain water phase mixture;
adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, vacuum emulsifying at 35MPa for 12min at 2800r/min, cooling to 32 deg.C, and aging for 8 hr.
Comparative example 1
This comparative example is different from example 1 in that hyaluronic acid was not added to the raw material.
Comparative example 2
This comparative example differs from example 1 in that no ceramide is added to the starting material.
Test results
1. Safety test
The composition prepared in the embodiment of the invention is subjected to a human body safety test, the test method refers to a skin repeatability open smearing test in 2015 cosmetic safety technical specification, and the test method comprises the following steps: 60 persons aged 18 to 60 years were selected and randomly divided into 6 groups, 4 groups corresponding to the compositions obtained using examples 1 to 4 of the present invention, and 5 to 6 groups corresponding to the compositions of comparative examples 1 to 2.
The specific test method comprises the following steps: selecting forearm skin area of 40mm 2 1g of the skin reaction liquid is applied once, 2 times of daily application and 7 days of continuous application, the skin reaction condition of a subject is recorded, and the skin reaction result of the subject is judged according to the highest reaction course of all observations, and the result is as follows:
TABLE 1 Scoring criteria
Figure BDA0003796221110000131
TABLE 2 human body safety test results
Group of The next day The fourth day Day six Total result
Example 1 0 0 0 Are all negative
Example 2 0 0 0 Are all negative
Example 3 0 0 0 Are all negative
Example 4 0 0 0 Are all negative
Comparative example 1 0 0 0 Are all negative
Comparative example 2 0 0 0 Are all negative
As can be seen from table 2, the compositions prepared in the examples of the present invention pass the human skin safety test.
2. Test of moisturizing Effect
A total of 60 women over 30-40 years old or women requiring moisturizing are selected as test subjects, and are randomly divided into 6 groups of 10 groups, wherein each group has no significant difference in age, skin properties and the like and is comparable, 4 groups use the compositions of examples 1-4 respectively, and 2 groups use the compositions of comparative examples 1-2 respectively.
The test method comprises the following steps: the composition is uniformly smeared on the arm cleaned by clear water of a subject, the skin moisture content before smearing and after smearing for 2h, 4h and 8h is respectively tested by a skin moisture tester, each group of results is an average value, and the test results are as follows:
table 3 moisturizing effect test results
Figure BDA0003796221110000141
As can be seen from table 3, the moisturizing effect of example 4 is better than that of the other examples, and the moisturizing and long-acting water-locking effects are good, and in comparison, the long-acting water-locking function of the comparative example is poor. The composition has better mutual synergy and promotion effect among the components, and the components are reasonably matched with each other, so that the composition has remarkable water replenishing and locking effect and has better repairing effect on skin barriers.
In summary, the composition of infant Tong Hufu of the present invention reproduces a skin-like structure by hyaluronic acid, ceramide, cholesterol and squalane components, inhibits water evaporation and relieves inflammatory reaction by increasing the thickness of the stratum corneum of the skin, and strengthens and toughens the skin barrier for sensitive and tender skin. The skin barrier repairing and protecting effects of the composition on skin are further improved by combining with other components, and the functions of moisturizing, promoting osmosis, improving skin immunity, regulating skin metabolism, promoting blood circulation, regulating skin grease secretion, supplementing skin nutrient components, inhibiting bacteria, resisting inflammation and the like are realized, so that the resistance of the skin of the infants to relief is improved, and the skin health is maintained. And the components are reasonable in proportion, so that the components have better synergistic promotion effect, the water replenishing and locking effect can be obviously enhanced, the skin barrier can be prevented from being damaged, and the damaged skin barrier can be repaired.
According to the preparation method of the infant Tong Hufu composition, disclosed by the embodiment of the invention, the components are mixed and merged according to the properties of the components, so that the dispersion degree of the components in the composition is better, the components can play a role, and the penetration effect of the components on skin can be enhanced, so that the skin absorption is enhanced, and the repair effect on the skin barrier is promoted.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (10)

1. The infant Tong Hufu composition is characterized by comprising the following components in parts by weight: 0.01-0.1 part of hyaluronic acid, 0.1-0.8 part of ceramide, 1-5 parts of amino acid, 1-5 parts of cholesterol, 5-15 parts of jojoba oil, 5-15 parts of sea buckthorn oil, 1-5 parts of squalane, 0.01-0.08 part of turmeric extract, 3-9 parts of aloe barbadensis extract, 1-10 parts of fucus extract, 2-12 parts of cucumber extract, 0.1-0.9 part of thickening agent and 100-150 parts of deionized water.
2. The infant Tong Hufu composition of claim 1 comprising, in parts by weight: 0.05 part of hyaluronic acid, 0.5 part of ceramide, 2 parts of amino acid, 3 parts of cholesterol, 8 parts of jojoba oil, 7 parts of sea buckthorn oil, 2 parts of squalane, 1 part of turmeric extract, 5 parts of aloe barbadensis extract, 5 parts of fucus extract, 10 parts of cucumber extract, 0.2 part of thickener and 130 parts of deionized water.
3. The infant Tong Hufu composition of claim 2 further comprising, in parts by weight, 0.01-0.08 parts panthenol and 0.1-1.2 parts lecithin.
4. The infant Tong Hufu composition of claim 3 further comprising 0.01-0.4 parts oat beta glucan by weight.
5. The infant Tong Hufu composition of claim 4 wherein the thickener is xanthan gum.
6. A method of making the infant Tong Hufu composition of any of claims 1-5 comprising the steps of: mixing cholesterol, thickener, jojoba oil, oleum Hippophae and squalane, heating and maintaining temperature to obtain oil phase mixture; mixing hyaluronic acid, ceramide and amino acid, adding deionized water, heating and keeping the temperature to obtain a water-phase mixture; adding the rest components into the water phase mixture, stirring, mixing, adding the oil phase mixture, and vacuum emulsifying.
7. The method of claim 6, wherein the infant Tong Hufu composition is heated to 80-95 ℃ for 10-20min.
8. The method of making the infant Tong Hufu composition of claim 7 wherein the heating rate is 1-3 ℃/min.
9. The preparation method of the infant Tong Hufu composition of claim 6, wherein during vacuum emulsification, emulsification is performed at 30-50MPa for 5-15min, and the rotation speed is 2000-3000r/min.
10. The method of preparing the infant Tong Hufu composition of claim 9, further comprising cooling to 30-40 ℃ and aging for 5-10 hours after vacuum emulsification.
CN202210969713.3A 2022-08-12 2022-08-12 Infant Tong Hufu composition and preparation method thereof Withdrawn CN115282105A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210969713.3A CN115282105A (en) 2022-08-12 2022-08-12 Infant Tong Hufu composition and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210969713.3A CN115282105A (en) 2022-08-12 2022-08-12 Infant Tong Hufu composition and preparation method thereof

Publications (1)

Publication Number Publication Date
CN115282105A true CN115282105A (en) 2022-11-04

Family

ID=83830107

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210969713.3A Withdrawn CN115282105A (en) 2022-08-12 2022-08-12 Infant Tong Hufu composition and preparation method thereof

Country Status (1)

Country Link
CN (1) CN115282105A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117860631A (en) * 2024-01-11 2024-04-12 广东领康日用品有限公司 Skin care composition with effect of effectively repairing skin barrier, and preparation process and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117860631A (en) * 2024-01-11 2024-04-12 广东领康日用品有限公司 Skin care composition with effect of effectively repairing skin barrier, and preparation process and application thereof

Similar Documents

Publication Publication Date Title
CN107296764B (en) Cream and preparation method thereof
CN111840144A (en) Moisturizing and repairing composition, skin care product and preparation method thereof
CN110638707A (en) Eye care cream and preparation method thereof
CN108653129B (en) Skin dressing containing natural plant anti-allergy composition
CN111529450A (en) Deep moisturizing repair composition, skin care product and preparation method thereof
CN114748367A (en) Moisturizing repair essence and preparation method thereof
CN115282105A (en) Infant Tong Hufu composition and preparation method thereof
CN107468610A (en) A kind of extraction product of rice bran shell and its application in facial-care
CN112773761B (en) Cosmetic composition, essence and preparation method thereof
CN110559226A (en) Whitening lotion and preparation method thereof
CN116196250B (en) Recombinant collagen freeze-dried mask with repairing effect and preparation method thereof
CN111012699A (en) Antioxidant oil-controlling emulsion containing fucoidan-kelp extract
CN111643722A (en) Sodium hyaluronate application containing icodextrin
CN110559227A (en) Skin cream for preventing and repairing striae gravidarum and preparation method thereof
CN114129490B (en) Sea buckthorn collagen anti-aging moisturizing facial mask and preparation method thereof
CN108619018B (en) Skin barrier repair cream and preparation method thereof
CN112057386A (en) Refreshing, moisturizing, whitening and repairing sun block and preparation method thereof
CN112137927A (en) Fibronectin essence emulsion with high penetration and light sensation reproduction and tissue regeneration initiation and preparation method thereof
CN115737456B (en) Skin cleansing scrub and preparation method thereof
CN112972276A (en) Moisturizing and hydrating face cream and preparation method thereof
CN116139050B (en) Essence water with microcapsule coated with sea buckthorn seed oil and grape seed oil and preparation method thereof
RU2780260C1 (en) Cosmetic for skin
CN114557906B (en) Moisturizing anti-aging collagen water gloss liquid and preparation method thereof
KR102637766B1 (en) Biodegradable film for improving skin function and method for preparing thereof
CN113908110A (en) Anti-aging traditional Chinese medicine skin care composition for periocular period and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20221104