CN115177852A - Stem cell exosome is with leading-in appearance of novel noninvasive intelligence - Google Patents
Stem cell exosome is with leading-in appearance of novel noninvasive intelligence Download PDFInfo
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- CN115177852A CN115177852A CN202210709349.7A CN202210709349A CN115177852A CN 115177852 A CN115177852 A CN 115177852A CN 202210709349 A CN202210709349 A CN 202210709349A CN 115177852 A CN115177852 A CN 115177852A
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- 210000001808 exosome Anatomy 0.000 title claims abstract description 22
- 210000000130 stem cell Anatomy 0.000 title claims abstract description 19
- 229940079593 drug Drugs 0.000 claims abstract description 10
- 239000003814 drug Substances 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims description 19
- 238000003780 insertion Methods 0.000 claims description 9
- 230000037431 insertion Effects 0.000 claims description 9
- 230000001954 sterilising effect Effects 0.000 claims description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 238000001514 detection method Methods 0.000 claims description 4
- 238000005516 engineering process Methods 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 6
- 230000005611 electricity Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 208000009043 Chemical Burns Diseases 0.000 description 2
- 208000018380 Chemical injury Diseases 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000003656 Electric Burns Diseases 0.000 description 1
- 108700011259 MicroRNAs Proteins 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005868 electrolysis reaction Methods 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- 230000036074 healthy skin Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000005424 photoluminescence Methods 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000037384 skin absorption Effects 0.000 description 1
- 231100000274 skin absorption Toxicity 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultraviolet radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention provides a novel noninvasive intelligent lead-in instrument for stem cell exosomes. The stem cell exosome includes with novel intelligent leading-in appearance of noninvasive: organism, first connecting wire, plug, spacing inserted block, sealed frame and two sterilamp, the bottom and the organism of first connecting wire are connected, the plug is connected with the top of first connecting wire, spacing inserted block sets up on the organism, first through-hole has been seted up at the top of spacing inserted block, sealed frame fixed mounting is on the bottom of spacing inserted block. The novel noninvasive intelligent lead-in instrument for the stem cell exosomes enhances the safety and reliability of the instrument, fully embodies the simple flexibility of operation, and simultaneously provides various output waveforms with adjustable widths and amplitudes by using a software programming technology, thereby greatly improving the efficiency of drug lead-in and widening the application range of the instrument.
Description
Technical Field
The invention belongs to the technical field of medical treatment, and particularly relates to a novel noninvasive intelligent lead-in instrument for stem cell exosomes.
Background
The cell exosome is a physiologically active substance secreted by cells in the process of physiological activity, the main functional components comprise protein substances and microRNA nucleic acid substances, and clinically, the stem cell exosome is mainly used for treating burns, scalds and skin ulcers and regenerating healthy skin; be used in the aspect of protecting the skin, mainly repair traumatism impaired, ageing poisoning skin, take care of skin, improve the skin quality comprehensively, and the leading-in appearance of the general cooperation of cell exosome uses, among the correlation technique, discloses a leading-in appearance of stem cell exosome noninvasive, including the organism, control panel is installed on the positive upper portion of organism, the area of contact pilot lamp is installed on the positive upper portion of control panel, current regulation knob is installed to the left end of the positive lower part of control panel, the right-hand member of the positive lower part of control panel is installed the vibration and is adjusted and push away the turn round, the standing groove has been seted up to the positive lower part of organism, the inner chamber swing joint of standing groove has the handle, and the one end fixedly connected with casing of handle, the mounting groove has been seted up to the inner chamber of casing, and vibrating motor is installed to the inner chamber of mounting groove. The invention solves the problems that the existing exosome introduction instrument has large volume and complicated operation, is inconvenient for people to use, cannot realize noninvasive introduction and is inconvenient for skin absorption by mutually matching the handle, the shell, the current adjusting knob, the contact area indicating lamp, the vibration adjusting push button, the pulse current emitter and the vibration motor.
However, the above-mentioned structure has disadvantages because the intelligent introduction instrument uses more direct current during the use process, the polarity is single, the generated polarization effect and electrolysis can reduce the efficiency of drug introduction, even can cause local chemical burn, and the direct current iontophoresis has limited applicable drugs.
Therefore, there is a need to provide a new stem cell exosome with a novel noninvasive intelligent introduction instrument to solve the above technical problems.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a novel noninvasive intelligent introduction instrument for the stem cell exosomes, which enhances the safety and reliability of the instrument, fully embodies the simple and flexible operation, simultaneously provides various output waveforms with adjustable widths and amplitudes by using a software programming technology, greatly improves the efficiency of drug introduction and widens the application range of the instrument.
In order to solve the technical problems, the novel noninvasive intelligent introduction instrument for the stem cell exosomes provided by the invention comprises: the ultraviolet sterilization lamp comprises a machine body, a first connecting wire, a plug, a limiting insertion block, a sealing frame and two ultraviolet sterilization lamps, wherein the bottom end of the first connecting wire is connected with the machine body;
the machine body is connected with a second connecting wire, a handle is slidably mounted on the first through hole, the top end of the handle extends to the position above the first through hole, the bottom end of the handle extends into a sealing frame, an intelligent lead-in instrument main body is arranged in the sealing frame and connected with the bottom end of the handle, the intelligent lead-in instrument main body is matched with the first through hole, a second through hole is formed in the handle, one end, far away from the machine body, of the second connecting wire extends into the second through hole and is connected with the intelligent lead-in instrument main body, a sealing ring is arranged in the first through hole and is matched with the handle and the intelligent lead-in instrument main body;
the intelligent lead-in instrument main body comprises an LED display, a microprocessor, a key, a controllable current source circuit, a high-voltage power supply, an electrode falling detection circuit, an alarm circuit, a complete machine power supply and the like.
As a further scheme of the invention, the microprocessor is a CPU, and the keys and the LED display are used for setting the time, the current and the working mode (current waveform) of the drug introduction.
As a further scheme of the invention, the key and the microprocessor are used for controlling the driving circuit to output specific current waveforms and intensities.
As a further scheme of the invention, the control drive circuit adopts a singlechip 89C51 as a core, an X25045 chip as power-down storage protection equipment and a keyboard and display special control chip BC7281.
As a further aspect of the present invention, the output circuit of the intelligent lead-in instrument main body employs a bridge driving circuit.
As a further scheme of the invention, the intelligent lead-in instrument main body adopts a module-program, and the program is divided into a main program and a plurality of sub-programs.
Compared with the related technology, the novel noninvasive intelligent introduction instrument for the stem cell exosomes provided by the invention has the following beneficial effects:
1. the invention is controlled by a single chip, enhances the safety and reliability of the instrument, fully embodies the simple flexibility of operation, simultaneously provides various output waveforms with adjustable width and amplitude by utilizing a software programming technology, greatly improves the efficiency of drug introduction and widens the application range of the instrument.
Drawings
In order to facilitate understanding for those skilled in the art, the present invention will be further described with reference to the accompanying drawings.
FIG. 1 is a functional block diagram of the present invention;
FIG. 2 is a power down protection circuit diagram of the present invention;
FIG. 3 is a schematic view of the present invention.
In the figure: 1. a body; 2. a first connecting wire; 3. a plug; 4. limiting the inserting block; 5. a sealing frame; 6. an ultraviolet germicidal lamp; 7. a second connecting wire; 8. a handle; 9. leading-in appearance main part of intelligence.
Detailed Description
Please refer to fig. 1, fig. 2 and fig. 3 in combination, wherein fig. 1 is a schematic block diagram of the present invention; FIG. 2 is a power down protection circuit diagram of the present invention; fig. 3 is a schematic structural diagram of the present invention. The appearance is introduced with novel noninvasive intelligence to stem cell exosome includes: the portable ultraviolet sterilization lamp comprises a machine body 1, a first connecting wire 2, a plug 3, a limiting insertion block 4, a sealing frame 5 and two ultraviolet sterilization lamps 6, wherein the bottom end of the first connecting wire 2 is connected with the machine body 1, the plug 3 is connected with the top end of the first connecting wire 2, the limiting insertion block 4 is arranged on the machine body 1, a first through hole is formed in the top of the limiting insertion block 4, the sealing frame 5 is fixedly arranged on the bottom of the limiting insertion block 4, the sealing frame 5 is communicated with the first through hole, and the two ultraviolet sterilization lamps 6 are arranged in the sealing frame 5;
the machine body 1 is connected with a second connecting wire 7, a handle 8 is slidably mounted on the first through hole, the top end of the handle 8 extends to the upper side of the first through hole, the bottom end of the handle 8 extends into a sealing frame 5, an intelligent lead-in instrument main body 9 is arranged in the sealing frame 5, the intelligent lead-in instrument main body 9 is connected with the bottom end of the handle 8, the intelligent lead-in instrument main body 9 is matched with the first through hole, a second through hole is formed in the handle 8, one end, far away from the machine body 1, of the second connecting wire 7 extends into the second through hole and is connected with the intelligent lead-in instrument main body 9, a sealing ring is arranged in the first through hole and is matched with the handle 8 and the intelligent lead-in instrument main body 9;
the intelligent lead-in instrument main body 9 is composed of an LED display, a microprocessor, a key, a controllable current source circuit, a high-voltage power supply, an electrode falling detection circuit, an alarm circuit, a complete machine power supply and the like.
After accomplishing leading-in work, take handle 8, then insert it in sealed frame 5, cause to drive leading-in appearance main part 9 of intelligence through handle 8 and insert in sealed frame 5, then start sterilamp 6 and operate, make it can come to carry out the work of disinfecting to leading-in appearance main part 9 of intelligence.
The microprocessor is a CPU, and the keys and the LED display are used for setting the time, the current and the working mode (current waveform) of the drug introduction.
The key and the microprocessor are used for controlling the drive circuit to output specific current waveform and intensity.
The control driving circuit adopts a singlechip 89C51 as a core, an X25045 chip as power-down storage protection equipment, and a keyboard and display special control chip BC7281.
The whole hardware structure of the intelligent lead-in instrument can be concise, and the reliability of the system of the intelligent lead-in instrument is obviously improved.
The output circuit of the intelligent lead-in instrument main body 9 adopts a bridge type driving circuit.
When the single-chip microcomputer is used, the single-chip microcomputer controls the polarity of the bridge circuit to enable the circuit to generate various output waveforms such as direct current, pulse, ultralow frequency alternating current, sparse-dense wave and the like, the amplitude and the width of each output waveform are adjustable along with the dosage, the diversity of the output waveforms avoids chemical burn during treatment, the limitation of the polarity of medicines is eliminated, and medicines which cannot be ionized and have unknown polarity can also be used for treatment.
The intelligent lead-in instrument main body 9 adopts a module-program, and the program is divided into a main program and a plurality of sub-programs.
Through the cooperation of main procedure and a plurality of subprograms to as function module the procedure of functions such as different mode (output different wave forms), output channel judgement, time of dosing and dose display and memory, just can realize the call of various function modules through the key value that BC7281 provided by the main procedure, in addition, because the human body has a process of adaptation to the electro photoluminescence, add the electricity suddenly and can bring very big uncomfortable sense for the patient, cause the electric burn even, consequently, adopted soft start to add the electricity design, it is a process that steps up to add the electricity for the electrode promptly for the singlechip.
As shown in fig. 2, in the diagram C, a large-capacity capacitor is used, and after power is off, the stored electric energy can maintain the single chip microcomputer to continue working for a period of time, so as to ensure that the current working data is written into X25045;
when the medical electrode is used, in the whole working process after the working key is pressed, whether the electrode is in reliable contact with a human body or not is automatically detected, if the electrode is in poor contact or falls off, the single chip microcomputer does not power on the electrode after obtaining information through the detection circuit, and meanwhile the alarm circuit gives an alarm to ensure the safety of a patient.
Claims (6)
1. The utility model provides a stem cell exosome is with leading-in appearance of novel noninvasive intelligence which characterized in that includes:
the ultraviolet sterilization lamp comprises a machine body, a first connecting wire, a plug, a limiting insertion block, a sealing frame and two ultraviolet sterilization lamps, wherein the bottom end of the first connecting wire is connected with the machine body, the plug is connected with the top end of the first connecting wire, the limiting insertion block is arranged on the machine body, a first through hole is formed in the top of the limiting insertion block, the sealing frame is fixedly arranged on the bottom of the limiting insertion block, the sealing frame is communicated with the first through hole, and the two ultraviolet sterilization lamps are arranged in the sealing frame;
the machine body is connected with a second connecting wire, a handle is slidably mounted on the first through hole, the top end of the handle extends to the position above the first through hole, the bottom end of the handle extends into a sealing frame, an intelligent lead-in instrument main body is arranged in the sealing frame and connected with the bottom end of the handle, the intelligent lead-in instrument main body is matched with the first through hole, a second through hole is formed in the handle, one end, far away from the machine body, of the second connecting wire extends into the second through hole and is connected with the intelligent lead-in instrument main body, a sealing ring is arranged in the first through hole and is matched with the handle and the intelligent lead-in instrument main body;
the intelligent lead-in instrument main body comprises an LED display, a microprocessor, a key, a controllable current source circuit, a high-voltage power supply, an electrode falling detection circuit, an alarm circuit, a complete machine power supply and the like.
2. The novel noninvasive intelligent inducting instrument for the stem cell exosomes according to claim 1, characterized in that: the microprocessor is a CPU, and the keys and the LED display are used for setting the time, the current and the working mode (current waveform) of the drug introduction.
3. The novel noninvasive intelligent introduction instrument for the stem cell exosomes according to claim 1, characterized in that: the key and the microprocessor are used for controlling the driving circuit to output specific current waveform and intensity.
4. The novel noninvasive intelligent introduction instrument for the stem cell exosomes according to claim 1, characterized in that: the control driving circuit adopts a singlechip 89C51 as a core, an X25045 chip as power-down storage protection equipment, and a keyboard and display special control chip BC7281.
5. The novel noninvasive intelligent introduction instrument for the stem cell exosomes according to claim 1, characterized in that: the output circuit of the intelligent lead-in instrument main body adopts a bridge type driving circuit.
6. The novel noninvasive intelligent introduction instrument for the stem cell exosomes according to claim 1, characterized in that: the intelligent lead-in instrument main body adopts a module-program, and the program is divided into a main program and a plurality of subprograms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210709349.7A CN115177852A (en) | 2022-06-21 | 2022-06-21 | Stem cell exosome is with leading-in appearance of novel noninvasive intelligence |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210709349.7A CN115177852A (en) | 2022-06-21 | 2022-06-21 | Stem cell exosome is with leading-in appearance of novel noninvasive intelligence |
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| Publication Number | Publication Date |
|---|---|
| CN115177852A true CN115177852A (en) | 2022-10-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202210709349.7A Pending CN115177852A (en) | 2022-06-21 | 2022-06-21 | Stem cell exosome is with leading-in appearance of novel noninvasive intelligence |
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| CN211068766U (en) * | 2018-10-16 | 2020-07-24 | 深圳宇石科技有限公司 | Micro-current beauty device |
| CN211273154U (en) * | 2019-10-16 | 2020-08-18 | 吕文樱 | Electric wave leading-in instrument for leading facial mask essence into skin |
| CN211912455U (en) * | 2020-02-25 | 2020-11-13 | 尹瀛浩 | Stem cell exosome noninvasive introduction instrument |
| CN214435709U (en) * | 2020-10-14 | 2021-10-22 | 江苏集萃新型药物制剂技术研究所有限公司 | Needleless injector |
-
2022
- 2022-06-21 CN CN202210709349.7A patent/CN115177852A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1247094A (en) * | 1999-09-28 | 2000-03-15 | 陈华丰 | Beautifying therapeutic apparatus |
| CN2514550Y (en) * | 1999-09-28 | 2002-10-02 | 玉骑 | Composite pulse generator for electric pulse beautifying apparatus |
| CN1562405A (en) * | 2004-04-14 | 2005-01-12 | 柴瑞海 | Electro-therapeutic apparatus for fast hitting at certain acupoints on meridian |
| CN101496930A (en) * | 2009-03-02 | 2009-08-05 | 中国医学科学院生物医学工程研究所 | Multifunctional therapeutic apparatus with drug-iontophoresis and interferential electric current stimulation |
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| CN206852906U (en) * | 2016-12-14 | 2018-01-09 | 史婷婷 | A kind of department of stomatology chlorination equipment |
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