CN101496930A - Multifunctional therapeutic apparatus with drug-iontophoresis and interferential electric current stimulation - Google Patents
Multifunctional therapeutic apparatus with drug-iontophoresis and interferential electric current stimulation Download PDFInfo
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- CN101496930A CN101496930A CN 200910067999 CN200910067999A CN101496930A CN 101496930 A CN101496930 A CN 101496930A CN 200910067999 CN200910067999 CN 200910067999 CN 200910067999 A CN200910067999 A CN 200910067999A CN 101496930 A CN101496930 A CN 101496930A
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Abstract
The invention discloses a medication ion infusion and interference electricity multifunctional therapeutic instrument, which is provided with a control unit, a DA converting circuit, a proportion amplifying circuit, an adder, a sinewave generating circuit, a waveform modulation circuit, a power amplifying circuit and an isolating output circuit which are connected in turn, wherein the output of the control unit is also connected to the waveform modulation circuit; the output of the DA converting circuit is also connected with the waveform modulation circuit and the power amplifying circuit respectively; an adjustable voltage is connected to the adder; and the control unit adopts a singlechip to control the conversion of therapeutic modes, four waveforms of the medication ion infusion, difference frequency of the interference electricity and generation of modulation waves. The multifunctional therapeutic instrument uses the singlechip for control and adjustment, and simultaneously adopts a power output circuit to realize two different physical therapeutic modes, namely the medication ion infusion and the interference electricity, so the instrument is more convenient to adjust, has more functions, reduces the production cost, and is favorable for popularization in common families. Each therapeutic mode has a plurality of output waveforms so as to prevent the human body from generating adaptability in use.
Description
Technical field
The present invention relates to a kind of medical therapeutic Instrument.Particularly relate to a kind of easy to use, functional diversities, production cost reduces greatly, the medicine ion that helps popularizing in common family imports and disturbs electric multifunction medical instrument.
Background technology
The medicine ion leading-in technique is to utilize electric field that medicine ion is imported in the human body through skin, mucosa or wound, in order to the method for treatment disease.Its principle is to utilize that some drugs can dissociate into ion in the medicine ion solution, and under the effect of unidirectional current field force, charged medicine ion produces directed moving.Year history surplus it has 200 as a kind of physical therapy means.But nineteen ninety Leudc has introduced " electron ion importing " this noun, and makes electron ion gatherer basic forming.Thereafter, people have carried out extensive studies to the instrument that is used for the medicine ion importing, introduced a kind of unidirectional square-wave frequency modulation intermediate frequency ion introducing apparatus as Chinese patent CN1190600, and for example U.S. Pat 20080021372 has also been introduced a kind of equipment that is used for iontophoresis.
Traditional static disturbs power technology to originate from the phase at the beginning of the fifties in last century, advocated by Austrian scholar Hans Nemec, it is to be 4000Hz with (4000 ± 100Hz) sinusoidal ac is by two groups of (four) electrode crossing input human bodies, and the electric current infall forms interference field in human body with the two-way frequency.In interference field, press the low frequency electricity synthetic modulating frequency current of the principle " interior life " of beat on the study of radio by 0~100Hz.This electric current is exactly a disturbance current, claims crossover current again.The method of using this disturbance current treatment disease is called the static interference electrotherapy.Afterwards, people have been developed dynamic interferential electrotherapy on the diathermic basis of traditional static interference, and it is with a low frequency signal static interference electric current to be carried out amplitude modulation(PAM), makes the variation of the intensity generating period of output current.Three-dimensional interferential electrotherapy is further to grow up on the basis of traditional static interferential electrotherapy and dynamic interferential electrotherapy, superposes mutually to intersect at the mobile alternating current of three dimensions with three the tunnel during treatment and imports human body.The self-interference electrotherapy has just been obtained a large amount of scholar experts' broad research since it is found that, relative instrument also emerges in an endless stream.Chinese patent CN1120961 has introduced a kind of efficient bi-directional symmetrical impulse disturbances therapeutic instrument, and and for example CN1076127 has introduced a kind of interference electric therapeutic equipment of biological field.
But in the prior art, the medicine ion guiding therapeutic apparatus is isolating two kinds of different therapeutic equipmentss with interference electric therapeutic equipment, function singleness, and production cost is higher, is only applicable to uses such as hospital and high-income group, is difficult to popularize the family in common income.In addition, this quasi-instrument all adopts analog circuit to realize mostly at present, makes adjusting dumb, and output can not variation.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind of simple in structure, easy to use, has medicine ion and imports the medicine ion importing of treatment and the multiple function of interference electrical therapy and disturb electric multifunction medical instrument.
The technical solution adopted in the present invention is: a kind of medicine ion imports and disturbs electric multifunction medical instrument, include: the control unit that is connected successively, DA change-over circuit, ratio amplifying circuit, adder, sinusoidal wave generation circuit, waveform modulated circuit, power amplification circuit and spacing output circuit, the output of described control unit is also connected to the waveform modulated circuit, the output of described DA change-over circuit also connects waveform modulated circuit and power amplification circuit respectively, and adjustable voltage is connected to adder.
Described control unit is the conversion of adopting the Single-chip Controlling therapeutic modality, four kinds of waveforms that medicine ion imports, difference frequency and the generation of modulation wave by wide band of disturbing electricity.
It is that continuous wave, discontinuous wave, density involve modulating wave that described medicine ion imports four kinds of waveforms, and frequency is in intermediate frequency and low-frequency range, output amplitude and pulsewidth scalable; Described interference electricity is static interference electricity, dynamic interference current and the three-dimensional electricity that disturbs, and output frequency, amplitude and difference frequency are adjustable, and the modulating wave that the modulation that medicine ion imports involves the interference electricity is square wave, triangular wave, sawtooth waveforms, sine wave, its cycle scalable.
Described adjustable voltage is to be provided by digital regulation resistance and operational amplifier, and two input foot INC of described digital regulation resistance are connected the output control terminal of control unit with U/D, its outfan foot R
wBe outfan output adjustable voltage, described operational amplifier and peripheral resistance are formed the in-phase proportion amplifying circuit.
Described DA change-over circuit includes four output channels that are made of decoder and 4 DA conversion chips that link to each other with decoder respectively, the input of each DA conversion chip all is the connected mode that adopts double buffering with being connected of control unit, the outfan of each DA conversion chip connects two power amplifiers, constitute the bipolarity way of output, described decoder provides chip selection signal for 4 DA conversion chips.
Described ratio amplifying circuit, sinusoidal wave generation circuit and adder include chip and two operational amplifiers, described two operational amplifiers and proportional amplifying circuit of peripheral resistor group and adder, the outfan of operational amplifier connects input 8 feet of chip, and 2 feet of chip constitute sinusoidal wave outfan.
Described waveform modulated circuit includes digital regulation resistance, the input foot R of described digital regulation resistance
HThe outfan that connects DA change-over circuit and sinusoidal wave generation circuit respectively, two input foot INC of digital regulation resistance are connected the output control terminal of control unit with U/D, the outfan foot R of described digital regulation resistance
wBe outfan output modulating wave.
Described power amplification circuit includes operational amplifier and two Darlington transistors, and described operational amplifier connects into a voltage follower, and the output of this voltage follower connects the push-pull circuit of being made up of two Darlington transistors.
Described spacing output circuit is to be made of isolating transformer.
Medicine ion of the present invention imports and disturbs electric multifunction medical instrument, the present invention carries out regulating and controlling by single-chip microcomputer, adopt a kind of power output circuit simultaneously, can realize that medicine ion imports and disturb electric two kinds of different naturopathy patterns, make instrument regulate more convenient, function is more various, reduced the production cost of instrument, helped popularizing in common family.In addition, every kind of treatment pattern has multiple output waveform, prevents during use that human body from producing adaptability.
Description of drawings
Fig. 1 is that medicine ion of the present invention imports and disturb the whole structured flowchart that constitutes of electric multifunction medical instrument;
Fig. 2 is the adjustable voltage circuit;
Fig. 3 is a DA change-over circuit schematic diagram;
Fig. 4 is ratio amplifying circuit, sinusoidal wave generation circuit and adder circuit schematic diagram;
Fig. 5 is the waveform modulated circuit theory diagrams;
Fig. 6 is power amplification circuit and back level totem pole;
Fig. 7 is four kinds of output waveforms that medicine ion imports;
Fig. 8 is the interference electricity output waveform of triangular modulation.
Wherein:
1: control unit 2:DA change-over circuit
3: ratio amplifying circuit 4: adder
5: sinusoidal wave generation circuit 6: waveform modulated circuit
7: power amplification circuit 8: spacing output circuit
The specific embodiment
Medicine ion of the present invention is imported and disturb electric multifunction medical instrument to make a detailed description below in conjunction with the embodiment accompanying drawing.
As shown in Figure 1, medicine ion of the present invention imports and disturbs electric multifunction medical instrument, includes: control unit 1, DA change-over circuit 2, ratio amplifying circuit 3, adder 4, sinusoidal wave generation circuit 5, waveform modulated circuit 6, power amplification circuit 7 and spacing output circuit 8.
Circuit connecting relation is: control unit 1 is connected to DA change-over circuit 2 and carries out digital-to-analogue conversion, the output of DA change-over circuit 2 is connected to the input of proportional amplifier 3, the output of proportional amplifier 3 is connected to an input of adder 4, adder 4 also connects adjustable voltage Vi, adder 4 is output as sinusoidal wave generation circuit 5 variable voltage is provided, carry out the adjusting of frequency by the Control of Voltage frequency, the output of sinusoidal wave generation circuit 5 is connected to waveform modulated circuit 6, and reaching the modulation of offset of sinusoidal ripple by the output waveform of control unit 1 control waveform modulation circuit 6, the spacing output circuit 8 that is connected to power amplification circuit 7 and back level is then realized the output of interference electrical therapy.
Medicine ion imports the output of modulating wave by control unit 1 control DA change-over circuit 2, be connected to waveform modulated circuit 6, output by control unit 1 control waveform modulation circuit 6 reaches the modulation that DA change-over circuit 2 is exported square waves, and the spacing output circuit 8 that is connected to power amplification circuit 7 and back level is then realized; Medicine ion imports other waveform by 2 outputs of control section 1 control DA change-over circuit, and the spacing output circuit 8 that is connected to power amplification circuit 7 and back level is then realized.
Described control unit 1 adopts single-chip microcomputer, and described single-chip microcomputer is the AT89C52 chip that adopts Atmel company, is responsible for the conversion of control therapeutic modality, four kinds of waveforms that medicine ion imports, difference frequency and the generation of modulation wave by wide band of disturbing electricity.Described medicine ion imports and is output as four-way, and four kinds of waveforms are that continuous wave, discontinuous wave, density involve modulating wave; The frequency of described four kinds of waveforms, amplitude and pulsewidth can be regulated by control unit 1, wherein, frequency range 0~10KHz, amplitude range 0~100mA, pulsewidth 0~500us, can be used for importing of low frequency medicine ion and intermediate frequency medicine ion and import, have the therapeutical effect of low-frequency current and electric current of intermediate frequency simultaneously.Described interference electricity is output as three tunnel: one tunnel frequency sine-wave in modulating wave is synthetic that is output as fixed frequency, two-way is output as the frequency sine-wave in modulating wave is synthetic that difference frequency is 0~300Hz in addition, the difference frequency of described sine wave and amplitude can be regulated by control unit 1, frequency can be regulated by regulating adjustable voltage Vi, adjustable voltage Vi scope 1.98V~19.8V, described frequency range 1KHz~10KHz, amplitude range 0~100mA can carry out the treatment of static interference electricity, dynamic interference current treatment and three-dimensional interference electrical therapy; The modulation that described medicine ion imports involves the low frequency modulations ripple that disturbs in the electricity and can be square wave, saw shape ripple, triangle and involve sine wave, and described modulation can be regulated range of accommodation 0.5s~20s by control unit 1 wave period.As Fig. 7, shown in Figure 8, wherein, Fig. 7 is four kinds of output waveforms that medicine ion imports; Wherein, (a) continuous wave, (b) discontinuous wave, (c) dilatational wave, (d) the synthetic modulating wave of saw shape ripple; Fig. 8 is the interference electricity output waveform of triangular modulation.
As shown in Figure 2, described adjustable voltage Vi is provided by digital regulation resistance U1 and operational amplifier U2, and two input foot INC of described digital regulation resistance U1 are connected the output control terminal of control unit 1 with U/D, its outfan foot R
wBe outfan output adjustable voltage, described operational amplifier U2 and peripheral resistance are formed the in-phase proportion amplifying circuit.
It is the X9313 chip that described digital regulation resistance U1 adopts model, and the P2.2 of single chip computer AT 89C52, P2.3 are connected to input pin INC and the U/D of X9313, output R
wBe connected to operational amplifier U2, described operational amplifier U2 is output as adjustable voltage Vi, realizes the adjusting of voltage Vi by control unit 1 control X9313.
As shown in Figure 3, described DA change-over circuit 2 includes four output channels that are made of decoder U3 and 4 DA conversion chip U4 that link to each other with decoder U3 respectively, the input of each DA conversion chip U4 all is the connected mode that adopts double buffering with being connected of control unit 1, the outfan of each DA conversion chip U4 connects two operational amplifiers, constitutes the bipolarity way of output.
The chip that described DA conversion chip U4 employing model is DAC0832 realizes that the P0 of single chip computer AT 89C52 is connected to the data input pin of DAC0832; Single-chip microcomputer P2.5, P2.6 and P2.7 connect the input of decoder U3, and the chip that described decoder U3 employing model is 74LS138 is realized, utilizes decoder U3 to provide chip selection signal CS and data transfer control signal XFER for 4 DA conversion chip U4; The output of DA conversion chip U4 is connected to two amplifiers, connects into the bipolarity way of output.Realize that by control unit 1 control DA conversion chip U4 output output waveform amplitude, frequency and medicine ion import the adjusting of pulsewidth.
As shown in Figure 4, described ratio amplifying circuit 3, sinusoidal wave generation circuit 5 and adder 4 include chip U5 and two operational amplifier U6, U7, proportional amplifying circuit 3 of described two operational amplifier U6, U7 and peripheral resistor group and adder 4, the outfan of operational amplifier U7 connects input 8 feet of chip U5, and 2 feet of chip U5 constitute sinusoidal wave outfan.
It is the chip of ICL8038 that described chip U5 adopts model, the outfan of DAC0832 in the DA change-over circuit 2 that medicine ion imports is connected to the ratio amplifying circuit, its output is connected to the input of adder, be connected to the pin 8 of ICL8038 chip U5 afterwards, change the voltage of the pin 8 of ICL8038 chip U5 by the output voltage of AT89C52 Single-chip Controlling DA conversion chip U4, thereby change sine wave freuqency, realize the output of difference frequency sine wave in the pin two output of ICL8038 chip U5.
As shown in Figure 5, described waveform modulated circuit 6 includes digital regulation resistance U8, the input foot R of described digital regulation resistance U8
HThe outfan that connects DA change-over circuit 2 and sinusoidal wave generation circuit 5 respectively, two input foot INC of digital regulation resistance U8 are connected the output control terminal of control unit 1 with U/D, the outfan foot R of described digital regulation resistance U8
HBe outfan output modulating wave.
It is the chip of X9313 that described digital regulation resistance U8 adopts model.The output of DA conversion chip DAC0832 and model are that the sinewave output end of the chip U5 of ICL8038 all is connected to the R that model is the digital regulation resistance U8 of X9313 by switch
HEnd by INC foot and the U/D foot of control unit 1 control X9313, has realized that medicine ion imports and disturb the modulating wave of electricity.
As shown in Figure 6, described power amplification circuit 7 includes operational amplifier U9 and two Darlington transistor Q1, Q2, and it is the chip of TL062 that described operational amplifier U9 adopts model.Described operational amplifier U9 connects into a voltage follower, and the output of this voltage follower connects the push-pull circuit of being made up of a PNP Darlington transistor Q2 (model DB682) and a NPN Darlington transistor Q1 (model DB681) and realizes power amplification.Described spacing output circuit 8 is to be made of isolating transformer, and amplifying circuit connects isolating transformer and isolates and export.
Claims (9)
1. a medicine ion imports and disturbs electric multifunction medical instrument, it is characterized in that, include: the control unit that is connected successively (1), DA change-over circuit (2), ratio amplifying circuit (3), adder (4), sinusoidal wave generation circuit (5), waveform modulated circuit (6), power amplification circuit (7) and spacing output circuit (8), the output of described control unit (1) is also connected to waveform modulated circuit (6), the output of described DA change-over circuit (2) also connects waveform modulated circuit (6) and power amplification circuit (7) respectively, and adjustable voltage (Vi) is connected to adder (4).
2. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that described control unit (1) is the conversion of adopting the Single-chip Controlling therapeutic modality, four kinds of waveforms that medicine ion imports, difference frequency and the generation of modulation wave by wide band of disturbing electricity.
3. medicine ion according to claim 2 imports and disturbs electric multifunction medical instrument, it is characterized in that, it is that continuous wave, discontinuous wave, density involve modulating wave that described medicine ion imports four kinds of waveforms, and frequency is in intermediate frequency and low-frequency range, output amplitude and pulsewidth scalable; Described interference electricity is static interference electricity, dynamic interference current and the three-dimensional electricity that disturbs, and output frequency, amplitude and difference frequency are adjustable, and the modulating wave that the modulation that medicine ion imports involves the interference electricity is square wave, triangular wave, sawtooth waveforms, sine wave, its cycle scalable.
4. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that, described adjustable voltage (Vi) is to be provided by digital regulation resistance (U1) and operational amplifier (U2), two input foot INC of described digital regulation resistance (U1) are connected the output control terminal of control unit (1) with U/D, its outfan foot R
WBe outfan output adjustable voltage, described operational amplifier (U2) and peripheral resistance are formed the in-phase proportion amplifying circuit.
5. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that, described DA change-over circuit (2) includes four output channels that are made of decoder (U3) and 4 the DA conversion chips (U4) that link to each other with decoder (U3) respectively, the input of each DA conversion chip (U4) all is the connected mode that adopts double buffering with being connected of control unit (1), the outfan of each DA conversion chip (U4) connects two power amplifiers, constitute the bipolarity way of output, described decoder (U3) is that 4 DA conversion chips (U4) provide chip selection signal.
6. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that, described ratio amplifying circuit (3), sinusoidal wave generation circuit (5) and adder (4) include chip (U5) and two operational amplifiers (U6, U7), described two operational amplifiers (U6, U7) and the proportional amplifying circuit of peripheral resistor group (3) and adder (4), the outfan of operational amplifier (U7) connects input 8 feet of chip (U5), and 2 feet of chip (U5) constitute sinusoidal wave outfan.
7. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that described waveform modulated circuit (6) includes digital regulation resistance (U8), the input foot R of described digital regulation resistance (U8)
HThe outfan that connects DA change-over circuit (2) and sinusoidal wave generation circuit (5) respectively, two input foot INC of digital regulation resistance (U8) are connected the output control terminal of control unit (1) with U/D, the outfan foot R of described digital regulation resistance (U8)
WBe outfan output modulating wave.
8. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that, described power amplification circuit (7) includes operational amplifier (U9) and two Darlington transistors (Q1, Q2), described operational amplifier (U9) connects into a voltage follower, and the output of this voltage follower connects the push-pull circuit of being made up of two Darlington transistors (Q1, Q2).
9. medicine ion according to claim 1 imports and disturbs electric multifunction medical instrument, it is characterized in that described spacing output circuit (8) is to be made of isolating transformer.
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Cited By (9)
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CN101961525A (en) * | 2010-10-19 | 2011-02-02 | 徐敏 | Combined therapeutic equipment for body conditioning and using method thereof |
CN105617529A (en) * | 2016-02-24 | 2016-06-01 | 王瑞新 | Medium-high frequency electrical acupuncture instrument |
CN105664356A (en) * | 2016-01-05 | 2016-06-15 | 孝感量子机电科技有限公司 | Method for modulating therapy prescription waveform of low and medium frequency therapeutic instrument, and electric circuit |
CN106730345A (en) * | 2017-01-20 | 2017-05-31 | 广州市健崎电子科技有限公司 | A kind of intermediate frequency synthetic therapeutic apparatus |
CN108310639A (en) * | 2018-03-07 | 2018-07-24 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus, system and method |
CN108434595A (en) * | 2018-03-23 | 2018-08-24 | 中国人民解放军空军航空医学研究所 | A kind of head-type brain electric stimulating instrument and its electrical stimulation method |
CN108664074A (en) * | 2018-07-03 | 2018-10-16 | 许少辉 | System is monitored based on Internet of Things hospital environment |
CN111317641A (en) * | 2019-12-26 | 2020-06-23 | 上海健康医学院 | Household intermediate frequency interference physiotherapy instrument circuit |
CN115177852A (en) * | 2022-06-21 | 2022-10-14 | 菲尔生物工程技术有限公司 | Stem cell exosome is with leading-in appearance of novel noninvasive intelligence |
Family Cites Families (4)
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FR2493154A1 (en) * | 1980-11-05 | 1982-05-07 | Berthelin Francis | Electrical respiratory stimulator - has two pairs of electrodes, placed at level of muscles of patient, supplied with AC of slightly varying frequencies |
CN1105275A (en) * | 1994-01-13 | 1995-07-19 | 王宣福 | Jingluo electrotherapeutic apparatus |
CN1129594A (en) * | 1995-12-26 | 1996-08-28 | 吴树田 | Mid-frequency therapeutic equipment used for computer massage and medicine introduction |
CN1698914A (en) * | 2005-06-08 | 2005-11-23 | 山西怡生堂医疗技术有限公司 | Method for treating cervical vertebra or lumbar vertebra disease by computer digital controlled medium-frequency wave and therapeutic device thereof |
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2009
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CN101961525A (en) * | 2010-10-19 | 2011-02-02 | 徐敏 | Combined therapeutic equipment for body conditioning and using method thereof |
CN105664356A (en) * | 2016-01-05 | 2016-06-15 | 孝感量子机电科技有限公司 | Method for modulating therapy prescription waveform of low and medium frequency therapeutic instrument, and electric circuit |
CN105664356B (en) * | 2016-01-05 | 2018-06-29 | 孝感量子机电科技有限公司 | A kind of modulation circuit of medium-low frequency therapeutical instrument treatment prescription waveform |
CN105617529A (en) * | 2016-02-24 | 2016-06-01 | 王瑞新 | Medium-high frequency electrical acupuncture instrument |
CN106730345A (en) * | 2017-01-20 | 2017-05-31 | 广州市健崎电子科技有限公司 | A kind of intermediate frequency synthetic therapeutic apparatus |
CN106730345B (en) * | 2017-01-20 | 2022-04-26 | 广州市健崎电子科技有限公司 | Intermediate frequency comprehensive therapeutic instrument |
CN108310639A (en) * | 2018-03-07 | 2018-07-24 | 北京大智商医疗器械有限公司 | Difference frequency electrical stimulation apparatus, system and method |
CN108434595A (en) * | 2018-03-23 | 2018-08-24 | 中国人民解放军空军航空医学研究所 | A kind of head-type brain electric stimulating instrument and its electrical stimulation method |
CN108664074A (en) * | 2018-07-03 | 2018-10-16 | 许少辉 | System is monitored based on Internet of Things hospital environment |
CN111317641A (en) * | 2019-12-26 | 2020-06-23 | 上海健康医学院 | Household intermediate frequency interference physiotherapy instrument circuit |
CN115177852A (en) * | 2022-06-21 | 2022-10-14 | 菲尔生物工程技术有限公司 | Stem cell exosome is with leading-in appearance of novel noninvasive intelligence |
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