CN115105128A - Automatic sampling device of nucleic acid - Google Patents

Automatic sampling device of nucleic acid Download PDF

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Publication number
CN115105128A
CN115105128A CN202210765617.7A CN202210765617A CN115105128A CN 115105128 A CN115105128 A CN 115105128A CN 202210765617 A CN202210765617 A CN 202210765617A CN 115105128 A CN115105128 A CN 115105128A
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CN
China
Prior art keywords
sampling
cotton swab
nucleic acid
sleeve
manipulator
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Pending
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CN202210765617.7A
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Chinese (zh)
Inventor
钱卫星
姚燕妹
贾宁
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Hangzhou Vocational and Technical College
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Hangzhou Vocational and Technical College
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Priority to CN202210765617.7A priority Critical patent/CN115105128A/en
Publication of CN115105128A publication Critical patent/CN115105128A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • A61B10/0051Devices for taking samples of body liquids for taking saliva or sputum samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0096Casings for storing test samples
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/14Fixators for body parts, e.g. skull clamps; Constructional details of fixators, e.g. pins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/10Ultraviolet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/22Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25JMANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J11/00Manipulators not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/24Medical instruments, e.g. endoscopes, catheters, sharps

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Robotics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Neurosurgery (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention relates to the technical field of nucleic acid sampling, and discloses an automatic nucleic acid sampling device which comprises a machine body, wherein a sampling window is arranged on the front side surface of the machine body, a sampling platform is arranged below the sampling window, a bracket for supporting and positioning the head of a human body is arranged on the sampling platform, a workbench is arranged in the machine body, a sampling manipulator and a swab taking manipulator are respectively arranged on two sides of the workbench, a storage rack for placing a reagent pipe frame is arranged on the upper side of the workbench, and a swab storage rack for storing swabs is arranged on the side wall, close to the swab taking and placing manipulator, in the machine body. The invention has the advantages of convenient use, high sampling efficiency and effective prevention of medical staff from being infected.

Description

Automatic sampling device of nucleic acid
Technical Field
The invention relates to the technical field of nucleic acid sampling, in particular to an automatic nucleic acid sampling device.
Background
Aiming at the existing globalized new coronavirus, nucleic acid detection is an effective means for detecting whether the virus is infected, the nucleic acid detection is increasingly popularized, the detection frequency is very high, and a large number of medical staff are required to carry out nucleic acid sampling work. The nucleic acid sampling generally comprises taking a cotton swab, extending the cotton swab into the pharyngeal posterior wall of a person to be sampled for sampling, and cutting off the cotton swab after sampling and putting the cotton swab into a reagent tube. When the sampling amount is very large, medical staff frequently performs the same action, great fatigue is generated, and the risk of infection exists in the sampling process.
Disclosure of Invention
In order to solve the problems of manual nucleic acid sampling in the prior art, the invention provides the automatic nucleic acid sampling device which is convenient to use, has high sampling efficiency and effectively avoids medical staff from being infected.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides an automatic sampling device of nucleic acid, includes the organism, the leading flank of organism is equipped with the sampling window, the below of sampling window is equipped with the sampling platform, be equipped with the bracket that is used for human head to support the location on the sampling platform, be equipped with the workstation in the organism, the both sides of workstation are equipped with the sampling manipulator respectively, get the cotton swab manipulator, the upside of workstation is equipped with the supporter that is used for placing the reagent pipe support, be close to in the organism and get and be equipped with the cotton swab storage frame that is used for storing the cotton swab on getting the lateral wall of putting cotton swab manipulator. A cotton swab wrapped in a bag is stored on a cotton swab storage rack, a cotton swab taking mechanical arm takes out the cotton swab and then opens the cotton swab, the cotton swab is transferred to a sampling mechanical arm, the lower jaw of a person to be sampled leans against a bracket to position the head (oral cavity position), the mechanical arm is adopted to convey the cotton swab to the pharyngeal back wall in the oral cavity of the person to be sampled for sampling, after sampling is completed, the cotton swab taking mechanical arm breaks the head of the cotton swab and puts the broken cotton swab into a reagent tube in a reagent tube rack, and a cotton swab stick is thrown into a waste material box, so that automatic sampling is realized; realize no manual work through this kind of sampling device, convenient to use, sampling efficiency are high, and then effectively avoid medical personnel by the risk of infection.
Preferably, a glass partition plate is arranged at the sampling window, a sampling hole is formed in the position, corresponding to the bracket, of the glass partition plate, and a cotton swab clamp is clamped on the sampling manipulator; during sampling, the sampling manipulator penetrates the cotton swab holder through the sampling hole and extends out of the glass partition plate.
Preferably, be fixed with the slide rail on the sampling platform, with slide rail sliding connection's sliding seat, the lower extreme and the sliding seat fixed connection of bracket are equipped with the screw rod parallel with the slide rail on the sampling platform, the one end of screw rod is connected with driving motor, the side of sliding seat is equipped with the swivel nut, the screw rod passes the swivel nut and forms threaded connection, be equipped with the disinfection storehouse on the sampling platform. After the bracket is used, the driving motor drives the screw rod to rotate, so that the sliding seat drives the bracket to move into the disinfection bin for disinfection, and cross infection among sampled persons is prevented.
Preferably, the number of the disinfection bins is two, the two disinfection bins are respectively arranged at two ends of the sampling platform, the inner side surfaces of the disinfection bins are provided with avoidance notches for the brackets to enter, the number of the brackets is two, and the lower ends of the two groups of brackets are fixedly connected with the sliding seat; when one bracket is used, the other bracket is disinfected in the disinfection bin. The two brackets are used alternately, one is used, and the other bracket is disinfected, so that the detection efficiency is improved.
Preferably, the top surface of the disinfection cabin is provided with a spray head for spraying the atomized disinfectant, and the outer side of the disinfection cabin is provided with an exhaust fan. Atomizing disinfectant of blowout in the atomising head to disinfect fast to the bracket, the exhaust fan is pneumatic during the disinfection, and gas flows to the outside from the centre, thereby prevents that the disinfectant of atomizing state from blowing to by the person who samples.
Preferably, a reagent pipe rack placing table is arranged on the lower side of the workbench in the rack, and a stacking manipulator used for transferring and stacking the reagent pipe racks is further arranged in the rack. The cotton swab after the sampling is packed into the reagent pipe, and after the reagent pipe in a reagent pipe support was all sampled and was used, the platform was placed to reagent pipe support transfer to through pile up neatly manipulator with the reagent pipe support, then regularly the manual work is taken away.
Preferably, a plurality of sterilizing boxes for sterilizing the cotton swab holders are arranged between the workbench and the storage rack, and the cotton swab holders are inserted into the sterilizing boxes in a one-to-one correspondence manner; the rear end of the cotton swab holder is fixed with a permanent magnet, the end part of the sampling manipulator is provided with a positioning sleeve, the bottom of the positioning sleeve is fixed with an electromagnet, and when the positioning sleeve is aligned with the rear end of the cotton swab holder and the electromagnet is positively electrified, the electromagnet attracts the cotton swab holder into the positioning sleeve; when the head of the cotton swab holder extends into the disinfection box, the electromagnet is electrified reversely, and the cotton swab holder is separated from the positioning sleeve under the action of repulsive force. The cotton swab clamp is required to be placed in a disinfection box for disinfection after being used once, so that cross infection is prevented; set up a plurality of disinfect boxes, all set up a cotton swab holder in every disinfect box, the sampling manipulator snatchs a cotton swab holder after the disinfection at every turn (all the other in the disinfection), will treat after the use that the cotton swab holder is put into the disinfect box, snatchs another cotton swab holder after the disinfection again to ensure that every cotton swab holder can both disinfect, reduce disinfection latency, improve sampling efficiency.
Preferably, the cotton swab holder comprises an outer barrel and an electric cylinder arranged at the inner end of the outer barrel, a sliding sleeve is fixed at the shaft end of the electric cylinder, a motor is arranged in the sliding sleeve, a rotary table is fixed at the shaft end of the motor, and a cotton swab holding assembly is arranged on the rotary table. The electric cylinder can drive the sliding sleeve to stretch out and draw back in the outer barrel, and when the cotton swab moves to a proper position, the motor drives the cotton swab to rotate, so that sampling is realized.
Preferably, the outer end of the sliding sleeve is provided with an end cover with an elliptical hole, the outer side surface of the rotary table is provided with a sliding rail which is distributed along the radial direction and a sliding block which is in sliding fit with the sliding rail, the cotton swab clamping assembly is fixedly connected with the sliding block through a connecting seat, the outer side of the rotary table is provided with a guide rod which is distributed in parallel with the sliding rail and penetrates through the connecting seat in a sliding mode, the guide rod is provided with a pressure spring A, the outer side of the connecting seat is provided with a bearing, and the bearing on the connecting seat is always kept in butt joint with the hole wall of the elliptical hole under the action of the pressure spring A. The motor drives the carousel rotation, and the connecting seat is rotatory round the inner wall of elliptical aperture to make the cotton swab do oval orbit and rotate, the sampling range of cotton swab head is wider, more is close artifical manual sampling, and sampling effect is good.
Preferably, the cotton swab clamping assembly comprises a guide sleeve fixed at the outer end of the connecting seat and a clamping sleeve arranged in the guide sleeve and connected with the guide sleeve in a sliding mode, a center hole used for inserting the cotton swab rod is formed in the center of the outer end of the guide sleeve, a pressure sensor is fixed at the inner end of the guide sleeve, and a pressure spring B is arranged between the pressure sensor and the inner end of the clamping sleeve. Pressure spring B makes cotton swab head and throat elastic contact, and pressure sensor can detect the pressure value, according to the length that pressure value control electric jar stretches out.
Therefore, the invention has the advantages of convenient use, high sampling efficiency and effective prevention of the medical staff from being infected.
Drawings
Fig. 1 is a schematic view of the overall structure of the present invention.
Fig. 2 is a partial exploded view of fig. 1.
Fig. 3 is a schematic view of the internal structure of the machine body.
FIG. 4 is a schematic view showing the connection of the working table, the sampling manipulator and the swab taking manipulator.
Fig. 5 is a schematic view of the connection between the sampling manipulator and the swab holder.
Fig. 6 is a schematic structural view of the cotton swab holder.
Fig. 7 is a schematic view of the structure of the cotton swab holder with the shaft end of the electric cylinder extending out.
Fig. 8 is a partially enlarged view of the portion B in fig. 7.
Fig. 9 is a schematic view showing the state that the bearing on the connecting base abuts against the inner wall of the elliptical hole.
Fig. 10 is a schematic view of fig. 9 after being rotated 90 degrees.
In the figure: the device comprises a machine body 1, a sampling window 2, a glass partition plate 200, a sampling hole 201, a sampling platform 3, a sliding rail 300, a sliding seat 301, a screw rod 302, a driving motor 303, a threaded sleeve 304, a disinfection bin 305, an avoiding notch 306, a spray head 307, an exhaust fan 308, a bracket 4, a workbench 5, a sampling manipulator 6, a positioning sleeve 60, an electromagnet 61, a swab taking manipulator 7, a reagent tube rack 8, a commodity shelf 9, a reagent tube rack placing table 10, a stacking manipulator 11, a swab storage rack 12, a waste bin 13, a swab holder 14, an outer cylinder 140, an electric cylinder 141, a sliding sleeve 142, a motor 143, a rotating disc 144, a sliding rail 1440, a sliding block 1441, a swab holding component 145, a guide sleeve 1450, a holding sleeve 1451, a pressure sensor 1452, a pressure spring B1453, an end cover 146, an elliptical hole 1460, a connecting seat 147, a guide rod 148, a pressure spring A149, a bearing 150, a disinfection box 15, a swab 16 and a permanent magnet 17.
Detailed Description
The invention is further described with reference to the accompanying drawings and the detailed description below:
the automatic nucleic acid sampling device comprises a machine body 1, a sampling window 2 is arranged on the front side face of the machine body 1, a sampling platform 3 is arranged below the sampling window, a bracket 4 used for supporting and positioning the head of a human body is arranged on the sampling platform, a workbench 5 is arranged in the machine body, sampling manipulators 6 and cotton swab taking manipulators 7 are respectively arranged on two sides of the workbench, a storage rack 9 used for storing a reagent pipe rack 8 is arranged on the upper side of the workbench, a reagent pipe rack placing platform 10 is arranged on the lower side of the workbench in the machine frame 1, a stacking manipulator 11 used for transferring and stacking the reagent pipe racks is further arranged in the machine frame, a cotton swab storage rack 12 used for storing cotton swabs is arranged on the side wall, close to the cotton swab taking and placing manipulator, in the machine frame 1, and a waste bin 13 is arranged in the machine frame.
A glass partition board 200 is arranged at the sampling window 2, a sampling hole 201 is arranged at the position, corresponding to the bracket, of the glass partition board, and a cotton swab clamp 14 is clamped on the sampling manipulator 6; during sampling, the sampling manipulator penetrates the cotton swab holder through the sampling hole and extends out of the glass partition plate. Be equipped with a plurality of disinfect boxes 15 that are used for the disinfection of cotton swab holder between workstation and the supporter, the cotton swab holder has a plurality ofly, and every cotton swab holder one-to-one inserts the disinfect box, through ultraviolet ray disinfection in the disinfect box, during the use, the sampling manipulator snatchs the cotton swab holder after the disinfection.
A sliding rail 300 and a sliding seat 301 connected with the sliding rail in a sliding manner are fixed on the sampling platform 3, the lower end of the bracket 4 is fixedly connected with the sliding seat, a screw 302 parallel to the sliding rail is arranged on the sampling platform, one end of the screw is connected with a driving motor 303, a threaded sleeve 304 is arranged on the side surface of the sliding seat, the screw penetrates through the threaded sleeve to form threaded connection, and a disinfection bin 305 is arranged on the sampling platform; the number of the disinfection bins 305 in the embodiment is two, the two disinfection bins are respectively arranged at two ends of the sampling platform, the inner side surface of the disinfection bin 305 is provided with an avoidance notch 306 for the bracket to enter, two groups of brackets are arranged, and the lower ends of the two groups of brackets are fixedly connected with the sliding seat; when one bracket is used, the other bracket is disinfected in the disinfection bin; the top surface of the disinfection bin 305 is provided with a spray head 307 for spraying atomized disinfectant, and the outer side of the disinfection bin is provided with an exhaust fan 308.
As shown in fig. 5, a permanent magnet 17 is fixed at the rear end of the cotton swab holder 14, a positioning sleeve 60 is arranged at the end of the sampling manipulator 6, an electromagnet 61 is fixed at the bottom of the positioning sleeve, and when the positioning sleeve is aligned with the rear end of the cotton swab holder and the electromagnet is positively electrified, the electromagnet attracts the cotton swab holder into the positioning sleeve; when the head of the cotton swab holder extends into the disinfection box, the electromagnet is electrified reversely, and the cotton swab holder is separated from the positioning sleeve under the action of repulsive force.
As shown in fig. 6-10, the swab holder 14 includes an outer cylinder 140, an electric cylinder 141 provided at an inner end of the outer cylinder, a sliding sleeve 142 fixed at an axial end of the electric cylinder, a motor 143 provided in the sliding sleeve, a rotating disc 144 fixed at an axial end of the motor, and a swab holding assembly 145 provided on the rotating disc; an end cover 146 with an elliptical hole 1460 is arranged at the outer end of the sliding sleeve 142, a sliding rail 1440 and a sliding block 1441 which is in sliding fit with the sliding rail are arranged on the outer side of the rotating disc 144, the cotton swab clamping assembly 145 is fixedly connected with the sliding block through a connecting seat 147, a guide rod 148 which is distributed in parallel with the sliding rail and penetrates through the connecting seat in a sliding manner is arranged on the outer side of the rotating disc, a pressure spring A149 is arranged on the guide rod, a bearing 150 is arranged on the outer side of the connecting seat 146, and the bearing on the connecting seat is always kept in butt joint with the hole wall of the elliptical hole under the action of the pressure spring A.
The cotton swab clamping assembly 145 comprises a guide sleeve 1450 fixed at the outer end of the connecting seat and a clamping sleeve 1451 arranged in the guide sleeve and connected with the guide sleeve in a sliding manner, a central hole for inserting a cotton swab rod is formed in the center of the outer end of the guide sleeve, a pressure sensor 1452 is fixed at the inner end of the guide sleeve, and a pressure spring B1453 is arranged between the pressure sensor and the inner end of the clamping sleeve.
The principle of the invention is as follows with reference to the attached drawings: a cotton swab wrapped in a bag is stored on a cotton swab storage rack, a sampling mechanical arm grabs and takes out a sterilized cotton swab holder in a sterilizing box, the cotton swab 16 is taken out by the cotton swab taking mechanical arm and is opened, the cotton swab is transferred to the cotton swab holder on the sampling mechanical arm and is held by a holding sleeve, the lower jaw of a person to be sampled leans against a bracket to position the head (oral cavity position), the cotton swab holder extends into a sampling hole by the mechanical arm, an electric cylinder shaft in the cotton swab holder extends to enable the cotton swab to extend into the oral cavity of the person to be sampled, a motor drives a turntable to rotate, the cotton swab does elliptic motion in the oral cavity (a manual sampling process is simulated), the sampling range of the cotton swab is wide, and the sampling is more accurate; after the sampling is good, get the cotton swab manipulator and break the cotton swab head, and put into the reagent pipe in the reagent pipe support with the cotton swab after breaking, the cotton swab stick is then lost into the waste bin, the sampling manipulator will make used cotton swab holder put back the disinfect box and disinfect, then another disinfected cotton swab holder of centre gripping, driving motor drives the sliding seat and removes simultaneously, make used bracket get into and disinfect in the disinfection storehouse, the bracket after the disinfection removes to the sampling position, for next person's sampling use. Realize no manual work through this kind of sampling device, convenient to use, sampling efficiency are high, and then effectively avoid medical personnel by the risk of infection.
In order to ensure the accuracy of the sampling position of the cotton swab, a camera can be arranged at the sampling window, the oral cavity position of the human body is further detected through the camera, and when the oral cavity detection position of the human body is matched with the set oral cavity position, the electric cylinder in the cotton swab holder 14 can drive the sliding sleeve to extend out; if the detected oral cavity position is inconsistent with the set oral cavity position, a prompt is sent to remind the detected person to finely adjust the position. The technical scheme of the oral cavity position detection is the prior art scheme, and specific contents are not expanded and described herein.
In the description of the present invention, it should be understood that directions or positional relationships indicated by upper, lower, left, right, inner end, outer end, one end, the other end, etc. are based on the directions or positional relationships shown in the drawings, and are only for the sake of clarity to describe the technical solutions of the present invention, and do not indicate or imply that the indicated devices or elements must have specific directions, be configured and operated in specific directions, and are not to be construed as limiting the present invention.
The above is only a specific embodiment of the present invention, but the technical features of the present invention are not limited thereto. Any simple changes, equivalent substitutions or modifications made based on the present invention to solve the same technical problems and achieve the same technical effects are within the scope of the present invention.

Claims (10)

1. The utility model provides an automatic sampling device of nucleic acid, includes the organism, the leading flank of organism is equipped with the sampling window, the below of sampling window is equipped with the sampling platform, characterized by, be equipped with the bracket that is used for human head to support the location on the sampling platform, be equipped with the workstation in the organism, the both sides of workstation are equipped with the sampling manipulator respectively, get the cotton swab manipulator, the upside of workstation is equipped with the supporter that is used for placing the reagent pipe support, be close to in the organism and get and be equipped with the cotton swab storage frame that is used for storing the cotton swab on getting the lateral wall of putting cotton swab model manipulator.
2. The automatic nucleic acid sampling device of claim 1, wherein a glass partition is arranged at the sampling window, a sampling hole is arranged at the position, corresponding to the bracket, of the glass partition, and a cotton swab holder is held on the sampling manipulator; during sampling, the sampling manipulator penetrates the cotton swab holder through the sampling hole and extends out of the glass partition plate.
3. The automatic nucleic acid sampling device of claim 1, wherein the sampling platform is fixed with a slide rail and a slide seat slidably connected with the slide rail, the lower end of the bracket is fixedly connected with the slide seat, the sampling platform is provided with a screw rod parallel to the slide rail, one end of the screw rod is connected with a driving motor, the side surface of the slide seat is provided with a threaded sleeve, the screw rod passes through the threaded sleeve to form a threaded connection, and the sampling platform is provided with a disinfection chamber.
4. The automatic nucleic acid sampling device of claim 3, wherein the number of the disinfection chambers is two, the two disinfection chambers are respectively arranged at two ends of the sampling platform, the inner side surfaces of the disinfection chambers are provided with avoidance notches for the brackets to enter, the number of the brackets is two, and the lower ends of the two brackets are fixedly connected with the sliding seat; one of the trays is sterilized in the sterilization chamber while the other tray is in use.
5. The automatic nucleic acid sampling device of claim 3 or 4, wherein the top surface of the disinfection chamber is provided with a spray head for spraying atomized disinfectant, and the outer side of the disinfection chamber is provided with an exhaust fan.
6. The automatic nucleic acid sampling device of claim 1, wherein a reagent tube rack placing table is provided in the rack at a lower side of the working table, and a palletizing manipulator for transferring the reagent tube racks to a stack is further provided in the rack.
7. The automatic nucleic acid sampling device of claim 2, wherein a plurality of sterilizing chambers for sterilizing the swab holders are arranged between the worktable and the rack, and the swab holders are inserted into the sterilizing chambers in a one-to-one correspondence manner; the rear end of the cotton swab holder is fixed with a permanent magnet, the end part of the sampling manipulator is provided with a positioning sleeve, the bottom of the positioning sleeve is fixed with an electromagnet, and when the positioning sleeve is aligned with the rear end of the cotton swab holder and the electromagnet is positively electrified, the electromagnet attracts the cotton swab holder into the positioning sleeve; when the head of the cotton swab holder extends into the disinfection box, the electromagnet is electrified reversely, and the cotton swab holder is separated from the positioning sleeve under the action of repulsive force.
8. The automatic nucleic acid sampling device according to claim 2 or 7, wherein the swab holder comprises an outer cylinder and an electric cylinder arranged at the inner end of the outer cylinder, a sliding sleeve is fixed at the shaft end of the electric cylinder, a motor is arranged in the sliding sleeve, a rotating disc is fixed at the shaft end of the motor, and a swab holding assembly is arranged on the rotating disc.
9. The automatic nucleic acid sampling device of claim 8, wherein the outer end of the sliding sleeve is provided with an end cap with an elliptical hole, the outer side of the rotating disc is provided with a radially distributed slide rail and a slide block in sliding fit with the slide rail, the swab clamping assembly is fixedly connected with the slide block through a connecting seat, the outer side of the rotating disc is provided with a guide rod which is distributed in parallel with the slide rail and slides through the connecting seat, the guide rod is provided with a pressure spring A, the outer side of the connecting seat is provided with a bearing, and the bearing of the connecting seat is always kept in abutment with the hole wall of the elliptical hole under the action of the pressure spring A.
10. The automatic nucleic acid sampling device of claim 9, wherein the swab clamping assembly comprises a guide sleeve fixed at the outer end of the connecting seat, and a clamping sleeve slidably connected with the guide sleeve and arranged in the guide sleeve, a central hole for inserting the swab rod is formed in the center of the outer end of the guide sleeve, a pressure sensor is fixed at the inner end of the guide sleeve, and a pressure spring B is arranged between the pressure sensor and the inner end of the clamping sleeve.
CN202210765617.7A 2022-07-01 2022-07-01 Automatic sampling device of nucleic acid Pending CN115105128A (en)

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Application Number Priority Date Filing Date Title
CN202210765617.7A CN115105128A (en) 2022-07-01 2022-07-01 Automatic sampling device of nucleic acid

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Application Number Priority Date Filing Date Title
CN202210765617.7A CN115105128A (en) 2022-07-01 2022-07-01 Automatic sampling device of nucleic acid

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CN115105128A true CN115105128A (en) 2022-09-27

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CN202210765617.7A Pending CN115105128A (en) 2022-07-01 2022-07-01 Automatic sampling device of nucleic acid

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CN (1) CN115105128A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117703133A (en) * 2023-08-08 2024-03-15 山东吉特工业科技股份有限公司 Intelligent sampling shelter and method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117703133A (en) * 2023-08-08 2024-03-15 山东吉特工业科技股份有限公司 Intelligent sampling shelter and method thereof
CN117703133B (en) * 2023-08-08 2024-05-07 山东吉特工业科技股份有限公司 Intelligent sampling shelter and method thereof

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