CN115057780B - 一种3,5-二硝基-4-氯三氟甲苯的制备方法及装置 - Google Patents
一种3,5-二硝基-4-氯三氟甲苯的制备方法及装置 Download PDFInfo
- Publication number
- CN115057780B CN115057780B CN202210940950.7A CN202210940950A CN115057780B CN 115057780 B CN115057780 B CN 115057780B CN 202210940950 A CN202210940950 A CN 202210940950A CN 115057780 B CN115057780 B CN 115057780B
- Authority
- CN
- China
- Prior art keywords
- mixed
- acid
- nitrate
- chlorotrifluoromethane
- dinitro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/80—Mixing plants; Combinations of mixers
- B01F33/836—Mixing plants; Combinations of mixers combining mixing with other treatments
- B01F33/8362—Mixing plants; Combinations of mixers combining mixing with other treatments with chemical reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00051—Controlling the temperature
- B01J2219/00074—Controlling the temperature by indirect heating or cooling employing heat exchange fluids
- B01J2219/00087—Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
- B01J2219/00094—Jackets
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210940950.7A CN115057780B (zh) | 2022-08-08 | 2022-08-08 | 一种3,5-二硝基-4-氯三氟甲苯的制备方法及装置 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210940950.7A CN115057780B (zh) | 2022-08-08 | 2022-08-08 | 一种3,5-二硝基-4-氯三氟甲苯的制备方法及装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN115057780A CN115057780A (zh) | 2022-09-16 |
CN115057780B true CN115057780B (zh) | 2023-02-03 |
Family
ID=83207598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202210940950.7A Active CN115057780B (zh) | 2022-08-08 | 2022-08-08 | 一种3,5-二硝基-4-氯三氟甲苯的制备方法及装置 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN115057780B (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4096195A (en) * | 1977-05-13 | 1978-06-20 | Gaf Corporation | Cyclic two-stage nitration process for preparing 4-chloro-3,5-dinitrobenzotrifluoride from 4-chlorobenzotrifluoride |
CN110483302A (zh) * | 2018-05-14 | 2019-11-22 | 江苏大华化学工业有限公司 | 一种3,5-二硝基-4-氯三氟甲苯废酸减排新工艺 |
CN111704550A (zh) * | 2020-06-28 | 2020-09-25 | 山东滨海瀚生生物科技有限公司 | 二硝基苯胺类原药中间体的工业化生产方法 |
CN113563197A (zh) * | 2021-07-31 | 2021-10-29 | 山东道可化学有限公司 | 一种连续绝热硝化制备3-硝基-4-氯三氟甲苯的方法及微反应设备 |
-
2022
- 2022-08-08 CN CN202210940950.7A patent/CN115057780B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4096195A (en) * | 1977-05-13 | 1978-06-20 | Gaf Corporation | Cyclic two-stage nitration process for preparing 4-chloro-3,5-dinitrobenzotrifluoride from 4-chlorobenzotrifluoride |
CN110483302A (zh) * | 2018-05-14 | 2019-11-22 | 江苏大华化学工业有限公司 | 一种3,5-二硝基-4-氯三氟甲苯废酸减排新工艺 |
CN111704550A (zh) * | 2020-06-28 | 2020-09-25 | 山东滨海瀚生生物科技有限公司 | 二硝基苯胺类原药中间体的工业化生产方法 |
CN113563197A (zh) * | 2021-07-31 | 2021-10-29 | 山东道可化学有限公司 | 一种连续绝热硝化制备3-硝基-4-氯三氟甲苯的方法及微反应设备 |
Also Published As
Publication number | Publication date |
---|---|
CN115057780A (zh) | 2022-09-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN113563197B (zh) | 一种连续绝热硝化制备3-硝基-4-氯三氟甲苯的方法及微反应设备 | |
CN108752161B (zh) | 连续流微通道反应器中合成单氯代邻二甲苯的方法 | |
KR0185424B1 (ko) | 수소와 산소로부터 과산화수소를 제조하는 방법 및 그 장치 | |
CN111018715A (zh) | 二硝基苯的微通道合成方法 | |
CN109665963B (zh) | 一种2,6-二甲基硝基苯的合成方法 | |
CN105384617B (zh) | 应用微反应器装置制备1‑氯‑1′‑氯乙酰基环丙烷的方法 | |
CN105418548A (zh) | 用于α-二羰基化合物α位氢原子氯代反应的微反应器及合成方法 | |
CN107628931B (zh) | 一种合成苯甲醚及其衍生物的微反应***与方法 | |
CN113754512B (zh) | 邻溴三氟甲苯的制备方法 | |
EP2948435B1 (en) | Facile method for preparation of 5-nitrotetrazolates using a flow system | |
CN103333126B (zh) | 一种2,6-二甲氧基吡嗪的硝化反应的方法 | |
CN115057780B (zh) | 一种3,5-二硝基-4-氯三氟甲苯的制备方法及装置 | |
CN111056934A (zh) | 一种微反应器内制备α-羟基酮光引发剂的方法 | |
CN218981525U (zh) | 一种硝基甲烷的连续流合成*** | |
CN115057781B (zh) | 一种硝基苯的生产方法 | |
CN114950320A (zh) | 一种连续合成四氟乙烷-β-磺内酯的装置和方法 | |
CN114984878A (zh) | 一种过氧乙酸的微反应连续合成方法及装置 | |
US8604256B2 (en) | Method for reducing the formation of by-product dinitrobenzene in the production of mononitrobenzene | |
CN113149896A (zh) | 一种3-氨基吡啶的制备方法 | |
CN115477589B (zh) | 一种连续化制备2-甲基-4-甲氧基苯胺的方法 | |
CN110963964A (zh) | 吡罗克酮的连续化合成方法 | |
CN115784861B (zh) | 一种连续化微通道技术生产三氯丙酮的方法 | |
CN115536587A (zh) | 一种用微通道硝化制备西地那非中间体的方法 | |
CN115197067A (zh) | 采用微通道反应器制备硝基苯的方法 | |
CN100448831C (zh) | 一种管道化连续生产辅酶q0的方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20221227 Address after: 262714 Yangkou Town, Shouguang City, Weifang City, Shandong Province Applicant after: SHANDONG EXCERIS CHEMICAL CO.,LTD. Applicant after: TSINGHUA University Address before: 262714 Yangkou Town, Shouguang City, Weifang City, Shandong Province Applicant before: SHANDONG EXCERIS CHEMICAL CO.,LTD. |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Deng Jian Inventor after: Li Jianfeng Inventor after: Wang Mengdi Inventor after: Qu Zhongxin Inventor after: Luo Guangsheng Inventor after: Xu Peng Inventor after: Peng Xueying Inventor after: Lu Fengyang Inventor after: Yu Wenzhi Inventor after: Zhang Chuo Inventor after: Zhang Changlei Inventor after: Yang Yuanyuan Inventor before: Peng Xueying Inventor before: Lu Fengyang Inventor before: Yu Wenzhi Inventor before: Zhang Chuo Inventor before: Zhang Changlei Inventor before: Yang Yuanyuan Inventor before: Li Jianfeng Inventor before: Wang Mengdi Inventor before: Qu Zhongxin |