CN115024324A - Pesticide bactericide and preparation method thereof - Google Patents

Pesticide bactericide and preparation method thereof Download PDF

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Publication number
CN115024324A
CN115024324A CN202210800273.9A CN202210800273A CN115024324A CN 115024324 A CN115024324 A CN 115024324A CN 202210800273 A CN202210800273 A CN 202210800273A CN 115024324 A CN115024324 A CN 115024324A
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agent
tricyclazole
kasugamycin
preservative
pesticidal
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CN115024324B (en
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成震涛
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Hebei Barn Biological Products Co ltd
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Hebei Barn Biological Products Co ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P3/00—Fungicides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Toxicology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a pesticide bactericide, which comprises 20-50% of active ingredients, 1-3% of dispersing agent, 4-6% of wetting agent, 2-3% of thickening agent, 4-6% of antifreezing agent, 0.2-0.4% of preservative, 0.2-0.4% of defoaming agent and the balance of water by mass percent; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20. The pesticide bactericide provided by the invention has protection and treatment effects and has a good effect of preventing and treating rice blast.

Description

Pesticide bactericide and preparation method thereof
Technical Field
The invention relates to a pesticide bactericide and a preparation method thereof, belonging to the field of pesticide bactericides.
Background
The tricyclazole mainly inhibits the formation of melanin of the attached spore, thereby inhibiting the spore germination and the formation of the attached spore, preventing the invasion of pathogenic bacteria and reducing the generation of the bacterial spores, has the main protection effect, is a protective bactericide with strong systemic property, and can quickly absorb the effective components by the roots, stems and leaves of the rice. Tricyclazole is a common pesticide for preventing and treating rice blast in rice production, has been used for more than 30 years since the application of 80 s in the last century, reports that resistance is generated to rice blast in part of regions but large-area resistance is not generated exist, and belongs to low-resistance risk pesticides. In practical use, tricyclazole is a specific drug for preventing rice blast, is used before the invasion of rice blast germs, has a very excellent control effect on protecting leaves and protecting seedlings, but the rice blast is a typical multi-cycle disease, can be infected and attacked from a rice seedling stage to a grouting and maturing stage, and is difficult to be applied before the infection of the rice blast germs in the rice planting process. If the Pyricularia oryzae attapulgus spore has already finished the melanism on the rice plant, the conidium has already invaded, can stop the disease spreading using the tricyclazole, but can't reach the function of preventing and curing the disease. Meanwhile, in the growing process of rice, rainstorm, typhoon and other weather often occur, rice leaf wounds can be caused, pathogenic bacteria can directly enter the rice body to be infected, tricyclazole cannot achieve the prevention effect, and the disease prevention effect is poor. The rapamycin is a weak alkaline antibiotic produced by streptomyces, has strong systemic property, has certain antibacterial activity on partial gram-positive and gram-negative bacteria and certain fungi, has strong osmotic force, can be quickly absorbed by plants and conducted to the whole plant, mainly interferes with the amino acid metabolism of a thallus esterase system, influences the synthesis of protein, and has obvious therapeutic effect on rice blast bacteria. Therefore, after the rice blast is attacked, the tricyclazole is compounded with kasugamycin and other treatment agents for use together, and the effect of protecting new leaves and healthy seedlings is good. Although both belong to systemic bactericides, the action mechanisms of the two are different, and no cross resistance is reported at present. The two effective components are mixed, so that the service life of the pesticide for preventing and treating the rice blast can be prolonged, the risk of resistance is avoided or reduced, and the prevention and treatment spectrum of the pesticide can be expanded.
The tricyclazole pure product is white crystal, the melting point is 187-188 ℃, and the vapor pressure is 266.6448 multiplied by 10 < -7 > Pa at 25 ℃. The solubility at 25 ℃ is: water 1.6g/l, dichloromethane 33%, ethanol 25%, methanol 25%, acetone 10.4%, acetonitrile 10.4%, cyclohexanone 10.0%, benzene 4.2%, xylene 2.1%, chloroform >500 g/l. Stable property, difficult decomposition by water and light, and thermal stability. Kasugamycin is stable in an acidic or neutral medium, is easy to damage and lose efficacy when being subjected to alkali, is insoluble in various organic solvents such as methanol, ethanol, propanol and benzene, and is easy to dissolve in water. Because tricyclazole belongs to an internal absorption bactericide, the size of original drug particles processed by the dosage form directly influences the absorption and utilization of the drug and finally influences the prevention and treatment effect of the product, and the smaller the particle size of the processed particles is, the better the final drug effect performance of the product is. In the existing field pesticide formulation, the product particles of missible oil and microemulsion are the finest and can reach the nanometer level, but because the original drug of tricyclazole has low solubility in the conventional organic solvent, a large amount of polar solvent is required to be added for processing the tricyclazole into missible oil or microemulsion, which causes great damage to the environment, so that the processing of the tricyclazole into the missible oil or microemulsion is not a reasonable formulation choice, and the processing of the tricyclazole into the missible oil or microemulsion into a solid wettable powder or granule formulation or a liquid suspending agent formulation is a reasonable choice according to the properties of the original drug. The suspending agent product is prepared by adopting a wet sanding technology and repeatedly grinding materials in a closed grinding device, so that the particle size of the product can be processed to be very fine, and can be processed to be 1-2 microns, and the absorption utilization rate of crops can be greatly improved. However, the solubility of the tricyclazole technical material in water reaches 1.6g/L, and the tricyclazole technical material belongs to a variety with high solubility in water, so that the processed suspending agent product can be subjected to austenite curing in the storage process, so that the product is crystallized and separated out, small particles are aggregated and grown, the particle size is increased, the drug effect is reduced, and even a product with high content of the suspending agent can be hardened at the bottom of the material due to austenite curing, so that the product cannot be used.
Therefore, the kasugamycin and tricyclazole fungicidal composition is also limited by the action conditions, the component properties and the production process, and thus the fungicidal composition has poor compatibility and low stability, and the full exertion of the drug effect is difficult. Therefore, the combination and compounding of different active ingredients are realized, and the limitations of the two on the combined formula and process are overcome, so that the stability of the bactericide is improved, and the pharmacodynamic action of the bactericidal composition can be enhanced, which is a difficult point of research.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provides a pesticide bactericide and a preparation method thereof.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
subject of the technology 1
The pesticide bactericide comprises 20-50% of active ingredients, 1-3% of dispersing agent, 4-6% of wetting agent, 2-3% of thickening agent, 4-6% of antifreezing agent, 0.2-0.4% of preservative, 0.2-0.4% of organic silicon defoaming agent, 0-0.2% of ascorbyl palmitate and the balance of water by mass percent; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20.
As some preferred embodiments of the present invention, the pesticidal fungicide further comprises 0.1% to 0.2% by mass of ascorbyl palmitate.
As some preferred embodiments of the invention, the pesticide bactericide comprises 22% of active ingredients, 2% of dispersing agents, 5% of wetting agents, 2.5% of thickening agents, 5% of antifreezing agents, 0.3% of preservatives, 0-0.3% of organic silicon defoaming agents and the balance of water in percentage by mass; the effective components are mixed according to the mass ratio of 1: 10 kasugamycin and tricyclazole.
As some preferred embodiments of the present invention, the wetting agent comprises at least one of methyl coco alcohol polyoxyethylene ether, sodium lauryl ether sulfate, L64 surfactant, maleic anhydride methacrylate copolymer
As some preferred embodiments of the invention, the wetting agent is L64 surfactant and maleic anhydride methacrylate copolymer in a mass ratio of 1: 0.8-1.2.
As some preferred embodiments of the present invention, the thickener includes at least one of magnesium aluminum silicate, xanthan gum, polyvinyl alcohol, sesbania gum, and white carbon black.
As some preferred embodiments of the present invention, the dispersant comprises at least one of lignosulfonate, polycarboxylate and polyoxyethylene ether phosphate.
As some preferred embodiments of the present invention, the anti-freezing agent comprises at least one of ethylene glycol, propylene glycol, glycerin, polyethylene glycol.
As some preferred embodiments of the present invention, the preservative comprises at least one of cason, sodium benzoate, and potassium sorbate.
As some preferred embodiments of the invention, the dispersant is a GY-D07 polycarboxylate dispersant; the antifreeze is glycol; the preservative is sodium benzoate.
Subject matter two
The invention provides a preparation method of a pesticide bactericide containing the technical subject, which comprises the following steps:
A. preparing 20-50% of active ingredients, 1-3% of a dispersing agent, 4-6% of a wetting agent, 2-3% of a thickening agent, 4-6% of an antifreezing agent, 0.2-0.4% of a preservative, 0-0.4% of an organic silicon defoaming agent, 0-0.2% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 50-70wt% of deionized water in the raw materials, shearing, and grinding to obtain particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest deionized water, thickening agent, antifreezing agent, preservative, organic silicon defoamer and ascorbyl palmitate into the ground material, shearing and stirring, adjusting the pH value to 5.5-7.5, sampling, testing and packaging after the qualified product is obtained, and warehousing.
As a preferred embodiment of the invention, the shearing is carried out for 20-30 min at the rotating speed of 10000 r/min-14000 r/min; the temperature of the grinding is 15-25 ℃.
As a preferred embodiment of the present invention, a method for producing a pesticidal bactericide comprising the technical subject-matter of the first aspect, comprises the steps of:
A. preparing 20-50% of active ingredients, 1-3% of a dispersing agent, 4-6% of a wetting agent, 2-3% of a thickening agent, 4-6% of an antifreezing agent, 0.2-0.4% of a preservative, 0-0.4% of an organic silicon defoaming agent, 0.1-0.2% of ascorbyl palmitate, and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 50-70wt% of deionized water in the raw materials, shearing, and grinding to obtain particle size DV 95 Less than or equal to 5.0 mu m, adding the preservative and the organic silicon defoamer into the ground material, and shearing and stirring to obtain a mixed ground material;
C. mixing the rest deionized water, the antifreezing agent and the thickening agent, and stirring to obtain a thickening agent solution;
D. homogenizing the mixed ground material, adding the thickening agent solution and the ascorbyl palmitate while homogenizing, adjusting the pH value to 5.5-7.5, sampling, testing, filling, packaging and warehousing.
As a preferred embodiment of the invention, the shearing is carried out for 20-30 min at the rotating speed of 10000 r/min-14000 r/min; the grinding temperature is 15-25 ℃; homogenizing under 20-30MPa for 20-35 min.
As a preferred embodiment of the present invention, citric acid, malic acid or tartaric acid is used for the pH adjustment.
Adopt the produced beneficial effect of above-mentioned technical scheme to lie in:
1. according to the invention, the kasugamycin and the tricyclazole are compounded to form the compound preparation, so that the compound preparation has protection and treatment effects and has a good effect of preventing and treating rice blast. The two have different sterilization mechanisms, can comprehensively exert respective sterilization advantages and have complementary effects. The results of mycelium growth rate measurement show that kasugamycin and tricyclazole have certain inhibitory activity on Pyricularia oryzae, the EC50 value of kasugamycin is 2.73 mg/L, and the EC50 value of tricyclazole is 22.65 mg/L.
2. The technical scheme is that the kasugamycin contains impurities, the impurities are easily decomposed by microorganisms to cause deterioration, the deterioration can be delayed by adding a preservative, but the deterioration cannot be prevented, so that the inventor researches that the antioxidant performance is improved by adding ascorbyl palmitate, but the suspension rate of a pesticide bactericide product cannot be guaranteed by adding the ascorbyl palmitate, and the suspension rate of the pesticide bactericide product can be kept by compounding and cooperating an L64 surfactant and a methacrylic acid maleic anhydride copolymer, so that the suspension rate of the pesticide bactericide product can be kept, the traditional organic silicon defoamer can be replaced, and the foaming performance is reduced.
3. The L64 surfactant and the methacrylic acid maleic anhydride copolymer can also form a good synergistic effect with the GY-D07 polycarboxylate dispersant, and can effectively inhibit the product crystallization phenomenon caused by austenite curing in the storage process of the product. GY-D07 polycarboxylate dispersant belongs to water-soluble, carboxylate polymer salt, has unique amphipathic structure, adsorbs firmly on the surface of original drug particle in the pesticide suspension system with the help of self anchor group, effectively reduces the interfacial free energy of original drug particle, weakens the tendency of merging between pesticide particles, and dispersant self-ionization simultaneously forms electric double layer on the surface of original drug particle, and steric hindrance formed by electric double layer and macromolecule itself makes dispersed original drug particle stably suspend and disperse in the suspension system. The L64 surfactant is a block copolymerization surfactant of EO and PO, and has the surface activity effects of emulsification, dispersion, wetting and the like.
4. According to the invention, the addition mode of the thickening agent and other additives is accurately controlled and adjusted, so that the compatibility of the system is improved, the collision probability of particles is reduced, the settling time of the particles is prolonged, and the suspension rate is improved while the storage stability is maintained.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail and fully with reference to the following embodiments.
All the substances in the formula can be purchased from the market, and the polycarboxylate is GY-D07 polycarboxylate dispersant and is purchased from chemical group of China company; l64 surfactant, available from Zhejiang Germany chemical industry Co., Ltd; the methacrylic acid maleic anhydride copolymer is purchased from Guangzhou Weber science and technology Limited, the average molecular weight is 6000, and the white carbon black is purchased from Jinan Kathon chemical Limited; the organic silicon defoamer is purchased from Guangzhou Square chemical industry Co., Ltd, model FTRT AF 1551; the effective components of kasugamycin and tricyclazole are kasugamycin raw medicine and tricyclazole raw medicine. The temperature for the following grinding was controlled to 15-25 ℃.
Example 1
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.2% of organic silicon defoamer and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest deionized water, thickening agent, antifreezing agent, preservative and organic silicon defoaming agent into the ground material, shearing at the rotating speed of 12000r/min for 25min, stirring, adjusting the pH value to 6.0 by using citric acid, sampling, testing, filling, packaging and warehousing.
Example 2
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 20% of active ingredients, 3% of dispersant sodium lignosulfonate, 4% of wetting agent, 2% of thickening agent, 4% of antifreezing agent, 0.4% of preservative Kathon and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole in a mass ratio of 1: 3; the wetting agent is prepared from the following components in a mass ratio of 2: 1:1 of methyl cocoalcohol polyoxyethylene ether, lauryl alcohol ether sodium sulfate and maleic anhydride methacrylate copolymer; the thickening agent is magnesium aluminum silicate; the antifreezing agent is propylene glycol and glycerol with the mass ratio of 1: 1;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 50wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 Less than or equal to 5.0 mu m, adding the rest deionized water, thickening agent, antifreezing agent and preservative into the ground material, shearing for 30min at the rotating speed of 10000r/min, stirring, adjusting the pH value to 7.5 by adopting tartaric acid, sampling, testing, filling, packaging and warehousing.
Example 3
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.2% of organic silicon defoamer, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest deionized water, thickening agent, antifreezing agent, preservative, organic silicon defoamer and ascorbyl palmitate into the ground material, shearing for 25min at the rotating speed of 12000r/min, stirring, adjusting the pH value to 6.0 by using citric acid, sampling, testing, filling, packaging and warehousing.
Example 4
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.2% of organic silicon defoamer, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is a methacrylic acid maleic anhydride copolymer; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) the grain size is less than or equal to 5.0 mu m, the rest deionized water, thickening agent, antifreezing agent, preservative, organic silicon defoamer and ascorbyl palmitate are added into the ground material, the material is sheared for 25min at the rotating speed of 12000r/min, the material is stirred, the pH value is adjusted to 6.0 by adopting citric acid, and the material is canned, packaged and warehoused after being sampled and tested to be qualified.
Example 5
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.2% of organic silicon defoamer, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant and a methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 1; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest deionized water, thickening agent, antifreezing agent, preservative, organic silicon defoamer and ascorbyl palmitate into the ground material, shearing for 25min at the rotating speed of 12000r/min, stirring, adjusting the pH value to 6.0 by using citric acid, sampling, testing, filling, packaging and warehousing.
Example 6
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 20% of active ingredients, 3% of dispersant sodium lignosulfonate, 4% of wetting agent, 2% of thickener magnesium aluminum silicate, 4% of antifreezing agent, 0.4% of preservative Kathon, 0.2% of organic silicon defoamer, 0.1% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-3; the wetting agent is an L64 surfactant and a methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 1.2; (ii) a The antifreezing agent is propylene glycol and glycerol with the mass ratio of 1: 1;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest 40wt% of deionized water, a thickening agent, an antifreezing agent, a preservative, an organic silicon defoaming agent and ascorbyl palmitate into the ground material, shearing at the rotating speed of 12000r/min for 25min, stirring, adjusting the pH value to 6.0 by using citric acid, sampling, testing, filling, packaging and warehousing.
Example 7
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 50% of active ingredients, 1% of dispersant tristyrylphenol polyoxyethylene ether phosphate, 6% of wetting agent, 3% of thickening agent, 6% of antifreezing agent, 0.2% of preservative potassium sorbate, 0.4% of organic silicon defoamer, 0.2% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-20; the wetting agent is an L64 surfactant and a methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 0.8; the thickening agent is prepared from the following components in percentage by mass of 1: 1:1 of magnesium aluminum silicate, polyvinyl alcohol and white carbon black;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest 40wt% of deionized water, a thickening agent, an antifreezing agent, a preservative, an organic silicon defoaming agent and ascorbyl palmitate into the ground material, shearing at the rotating speed of 12000r/min for 25min, stirring, adjusting the pH value to 6.0 by using citric acid, sampling, testing, filling, packaging and warehousing.
Example 8
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 Less than or equal to 5.0 μm, adding the rest deionized water, thickening agent, antifreezing agent, antiseptic, and ascorbyl palmitate into the ground material, shearing at 12000r/min for 25min, stirring, and adding citric acidAdjusting the pH value to 6.0, sampling, testing, filling, packaging and warehousing.
Example 9
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is methacrylic acid maleic anhydride copolymer; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 And (3) the grain size is less than or equal to 5.0 mu m, the rest deionized water, thickening agent, antifreezing agent, preservative and ascorbyl palmitate are added into the ground material, the material is sheared for 25min at the rotating speed of 12000r/min, the material is stirred, the pH value is adjusted to 6.0 by citric acid, and the material is canned, packaged and warehoused after being sampled and tested to be qualified.
Example 10
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant and a methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 1; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 Less than or equal to 5.0 mu m, and then adding the rest deionized water, thickening agent, antifreezing agent, preservative and ascorbyl palmitic acid into the ground materialAnd (3) cutting the ester for 25min at the rotating speed of 12000r/min, stirring, adjusting the pH value to 6.0 by adopting citric acid, and filling, packaging and warehousing after sampling and testing are qualified.
Example 11
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is L64 surfactant and methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 1; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 Less than or equal to 5.0 mu m, adding the preservative and the organic silicon defoamer into the ground material, shearing for 25min at the rotating speed of 12000r/min, and stirring to obtain a mixed ground material;
C. mixing the rest deionized water, the antifreezing agent and the thickening agent, and stirring to obtain a thickening agent solution;
D. homogenizing the mixed ground material at 25MPa for 30min, adding thickener solution and ascorbyl palmitate while homogenizing, adjusting pH to 6.0, sampling, testing, bottling, packaging and warehousing.
Comparative example 1
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant and a methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 1; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersant and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 Less than or equal to 5.0 mu m, adding a preservative, an organic silicon defoamer and ascorbyl palmitate into the ground material, shearing for 25min at the rotating speed of 12000r/min, and stirring to obtain a mixed ground material;
C. mixing the rest deionized water, the antifreezing agent and the thickening agent, and stirring to obtain a thickening agent solution;
D. homogenizing the mixed and ground material at 25MPa for 30min, adding thickener solution while homogenizing, adjusting pH to 6.0, sampling, testing, bottling, packaging and warehousing.
Comparative example 2
A preparation method of a pesticide bactericide comprises the following steps:
A. preparing 22% of active ingredients, 2% of GY-D07 polycarboxylate dispersant, 5% of wetting agent, 2.5% of thickening agent, 5% of antifreezing agent ethylene glycol, 0.3% of preservative sodium benzoate, 0.15% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole with the mass ratio of 1-10; the wetting agent is an L64 surfactant and a methacrylic acid maleic anhydride copolymer in a mass ratio of 1: 1; the thickening agent is prepared from the following components in percentage by mass of 1: 0.4 parts of xanthan gum and sesbania gum;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 60wt% of deionized water in the raw materials, shearing for 25min at the rotating speed of 12000r/min, and grinding to obtain the particle size DV 95 Less than or equal to 5.0 mu m, adding the preservative and the organic silicon defoamer into the ground material, shearing for 25min at the rotating speed of 12000r/min, and stirring to obtain a mixed ground material;
C. mixing the rest deionized water, the antifreezing agent and the thickening agent, and stirring to obtain a thickening agent solution;
D. mixing the mixed ground material, the thickening agent solution and the ascorbyl palmitate, homogenizing at 25MPa for 30min, adjusting the pH value to 6.0, sampling, testing, filling, packaging and warehousing.
The bactericides of examples 1 to 11 and comparative examples 1 to 2 were subjected to measurement of properties such as suspension property, heat storage stability, and long-lasting foamability. The suspension rate is determined by referring to a GB/T14825-2006 pesticide suspension rate determination method, and the decomposition rate is determined by referring to GB/T19136-2003 pesticide heat storage stability standard. Referring to a method for measuring the lasting foamability of GB T28137-2011 pesticide, the foamability of the pesticide is measured for 1min by using a 250ml stopple graduated flask after being diluted by 250 times by using standard hard water specified in GB/T28137-2011 (the standard hard water specified in GB/T28137-2011 is 342mg/L calculated by calcium carbonate);
the pesticide bactericide of the embodiment 1-11 and the comparative example 1-2 is used for actual sterilization and prevention of rice blast, and the using amount of the effective component is 198ga.i./hm 2 The results of the pesticide field efficacy test using the spray application method are shown in table 1.
TABLE 1
Figure DEST_PATH_IMAGE002
Due to space limitation, the specific contents of the pesticide effect test of the pesticide bactericide obtained in example 5 are shown, and the pesticide effect test methods of other examples are the same. The pesticide bactericide of the embodiment 5 of the invention is used for actual sterilization and prevention of rice blast and pesticide field efficacy tests, and the specific contents of the tests are as follows:
protocol record number 2017-Octagon bacterium-1, sample seal number Ji 2017280, test year 2017, test location: yunnan, test unit: the plant protection college of Yunnan agricultural university, the use method is as follows: spraying, application time, and onset of disease.
Figure DEST_PATH_IMAGE004
The dosage and treatment number are shown in Table 2-1.
TABLE 2-1 test design for test agents
Figure DEST_PATH_IMAGE006
Figure DEST_PATH_IMAGE008
Figure DEST_PATH_IMAGE010
4.1 Meteorological and soil data
The first application day (9 months and 11 days) is raining and breezy, the air temperature is 20-28 ℃, and the air humidity is 86%; the day of the second application (9 months and 18 days) is rainy, the air temperature is 20-28 deg.C, the air humidity is 85%, and breeze is slight. It did not rain within 5 hours after two times of administration. During the test, the rainy day is mainly used, the highest temperature of the day is 30 ℃, and the lowest temperature is 19 ℃. See meteorological data table 2-2 for details.
TABLE 2-2 Meteorological data sheet during test
Figure DEST_PATH_IMAGE012
Figure DEST_PATH_IMAGE014
Figure DEST_PATH_IMAGE016
Figure DEST_PATH_IMAGE018
5 results and analysis
The results of field efficacy tests for controlling rice blast using a 22% chunlei tricyclazole suspending agent (agent in example 2) as a test agent are shown in tables 2-3. As is clear from tables 2 to 3, each 667m 2 50ml, 55 ml and 60 ml of 22% kasugamycin-tricyclazole suspending agent and 100 ml of 2% kasugamycin aqueous solution and 75% tricyclazole water dispersible granules serving as contrast agentsThe control effect 8 days after the first dose of the preparation is 67.19%, 74.51%, 81.76%, 69.82% and 68.96%. The control effect 7 days after the second administration is 70.61%, 82.44%, 90.17%, 73.21% and 77.73% respectively. By statistical analysis of the control effect 7 days after the second application, the difference of the control effect of 3 doses of the 22% chunlei tricyclazole suspending agent on rice blast is extremely obvious, namely the control effect is extremely improved along with the increase of the application amount, 55 ml treatment of the 22% chunlei tricyclazole suspending agent has extremely obvious difference with 100 ml of a 2% kasugamycin aqueous solution serving as a contrast agent, and has extremely obvious difference with 20 g control effect of 75% tricyclazole water dispersible granules (table 2-3).
TABLE 2-322% Chunlei tricyclazole suspending agent field test result for preventing and controlling rice blast
Second drug 7 days investigation
Figure DEST_PATH_IMAGE020
Figure DEST_PATH_IMAGE022
Thus, the test agent 22% chunlei tricyclazole suspending agent (example 2 agent) has better control effect on rice blast, and each 667m 2 The rice blast prevention effect of 55-60 ml of the pesticide for two times can reach 82.44-90.17 percent. The dosage of the test reagent is safe to rice, has no chemical injury and no adverse effect on environment, and is suitable for large-area popularization and use.
According to the invention, no antagonism is generated after kasugamycin and tricyclazole are mixed, and formula screening test results show that no antagonism is generated after kasugamycin and tricyclazole are mixed within the range of 1:3-1: 20. After the two are mixed according to the proportion of 1: 6, 1: 8, 1: 10, 1: 12 and 1: 14, SR values are respectively 1.60, 1.65, 1.62, 1.55 and 1.60, which shows that the synergistic effect is achieved.
The result of the measurement of the growth rate of mycelium shows that kasugamycin and tricyclazole have certain inhibitory activity to Pyricularia oryzae, the EC50 value of kasugamycin is 2.73 mg/L, and the EC50 value of tricyclazole is 22.65 mg/L.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.

Claims (10)

1. The pesticide bactericide is characterized by comprising 20-50% of active ingredients, 1-3% of dispersing agent, 4-6% of wetting agent, 2-3% of thickening agent, 4-6% of antifreezing agent, 0.2-0.4% of preservative, 0-0.4% of organic silicon defoaming agent, 0-0.2% of ascorbyl palmitate and the balance of water in percentage by mass; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20.
2. The pesticidal fungicide according to claim 1, characterized in that the pesticidal fungicide further comprises 0.1% to 0.2% of ascorbyl palmitate.
3. The pesticidal fungicide according to claim 1 or 2, wherein the wetting agent comprises at least one of methyl coco alcohol polyoxyethylene ether, sodium lauryl ether sulfate, L64 surfactant, maleic anhydride methacrylate copolymer.
4. The pesticide bactericide as claimed in claim 3, wherein the wetting agent is L64 surfactant, maleic anhydride methacrylate copolymer in a mass ratio of 1: 0.8-1.2.
5. The pesticidal fungicide according to claim 1 or 2, wherein the thickener comprises at least one of magnesium aluminum silicate, xanthan gum, polyvinyl alcohol, sesbania gum and white carbon black.
6. The pesticidal fungicide according to claim 1 or 2, wherein the dispersant comprises at least one of lignosulfonate, polycarboxylate and polyoxyethylene ether phosphate.
7. The pesticidal fungicide according to claim 1 or 2, wherein the antifreeze agent comprises at least one of ethylene glycol, propylene glycol, glycerin, polyethylene glycol.
8. The pesticidal fungicide according to claim 1 or 2, wherein the preservative comprises at least one of cason, sodium benzoate and potassium sorbate.
9. The method for producing a pesticidal bactericidal agent according to claim 2, characterized by comprising the steps of:
A. preparing 20-50% of active ingredients, 1-3% of a dispersing agent, 4-6% of a wetting agent, 2-3% of a thickening agent, 4-6% of an antifreezing agent, 0.2-0.4% of a preservative, 0-0.4% of an organic silicon defoaming agent, 0-0.2% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 50-70wt% of deionized water in the raw materials, shearing, and grinding to obtain the particle size DV 95 And (3) less than or equal to 5.0 mu m, adding the rest deionized water, thickening agent, antifreezing agent, preservative, organic silicon defoamer and ascorbyl palmitate into the ground material, shearing and stirring, adjusting the pH value to 5.5-7.5, sampling, testing and packaging after the qualified product is obtained, and warehousing.
10. The method for producing a pesticidal bactericidal agent according to claim 2, characterized by comprising the steps of:
A. preparing 20-50% of active ingredients, 1-3% of a dispersing agent, 4-6% of a wetting agent, 2-3% of a thickening agent, 4-6% of an antifreezing agent, 0.2-0.4% of a preservative, 0-0.4% of an organic silicon defoaming agent, 0.1-0.2% of ascorbyl palmitate and the balance of water according to mass percentage; the effective components are kasugamycin and tricyclazole in a mass ratio of 1:3-1: 20;
B. mixing tricyclazole, kasugamycin, wetting agent, dispersing agent and 50-70wt% of deionized water in the raw materials, shearing, and grinding to obtain particle size DV 95 Less than or equal to 5.0 mu m, adding the preservative and the organic silicon defoamer into the ground material, and shearing and stirring to obtain a mixed ground material;
C. mixing the rest deionized water, the antifreezing agent and the thickening agent, and stirring to obtain a thickening agent solution;
D. homogenizing the mixed ground material, adding thickener solution and ascorbyl palmitate while homogenizing, adjusting pH to 5.5-7.5, sampling, testing, bottling, packaging and warehousing.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102057921A (en) * 2010-12-14 2011-05-18 江苏省绿盾植保农药实验有限公司 Fungicide containing tricyclazole and kasugamycin
US20140187508A1 (en) * 2012-12-31 2014-07-03 Dow Agroscience Llc Synergistic fungicidal compositions
CN111903689A (en) * 2020-07-31 2020-11-10 上海悦联生物科技有限公司 Bactericide containing picoxystrobin and propiconazole and preparation method and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102057921A (en) * 2010-12-14 2011-05-18 江苏省绿盾植保农药实验有限公司 Fungicide containing tricyclazole and kasugamycin
US20140187508A1 (en) * 2012-12-31 2014-07-03 Dow Agroscience Llc Synergistic fungicidal compositions
CN111903689A (en) * 2020-07-31 2020-11-10 上海悦联生物科技有限公司 Bactericide containing picoxystrobin and propiconazole and preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
任家琼: "22％春雷霉素•三环唑悬浮剂对稻瘟病的田间防效试验", 《植物医生》, vol. 33, no. 4, pages 104 - 108 *

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