CN114917317A - Compound foot-soaking medicine bag containing active vinasse and preparation method thereof - Google Patents

Compound foot-soaking medicine bag containing active vinasse and preparation method thereof Download PDF

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CN114917317A
CN114917317A CN202210751593.XA CN202210751593A CN114917317A CN 114917317 A CN114917317 A CN 114917317A CN 202210751593 A CN202210751593 A CN 202210751593A CN 114917317 A CN114917317 A CN 114917317A
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vinasse
parts
active
steps
method comprises
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CN114917317B (en
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黄永光
姚超
朱家合
管波
邓龙云
肖彬玉
余留芬
熊小月
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Guizhou Yanbo Liquor Industry Co ltd
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Guizhou Yanbo Liquor Industry Co ltd
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Abstract

The invention provides a compound foot bath medicine bag containing active vinasse and a preparation method thereof, wherein the compound foot bath medicine bag comprises the following raw materials in parts by weight: 40-50 parts of active vinasse, 3.0-5.0 parts of ginger, 6.5-9.5 parts of dittany bark, 3.0-4.0 parts of dried orange peel, 5.0-8.0 parts of glabrous greenbrier rhizome, 3.0-4.0 parts of lightyellow sophora root, 5.0-7.0 parts of sessile stemona root and 3.0-5.0 parts of Qixingjian. The compound foot-soaking medicine bag provided by the invention can effectively promote blood circulation, treat beriberi and tinea pedis, relax muscles and tendons, activate blood, ventilate, activate blood, relieve fatigue, condition spleen and stomach and improve sleep quality.

Description

Compound foot bath medicine bag containing active vinasse and preparation method thereof
Technical Field
The invention relates to the technical field of foot bath medicine bags, in particular to a compound foot bath medicine bag containing active vinasse and a preparation method thereof.
Background
The feet are the important components of the human body, a large number of researches have fully proved that the feet of people have associated areas, response areas and a plurality of meridian distributions corresponding to all internal organs of the body, and the process of soaking the feet by warm water can activate, sensitize and stimulate the associated areas and the response areas on the feet, promote the functions of the response areas and the meridians to stimulate and regulate, accelerate the effective circulation of blood of the human body, regulate the metabolism of the human body, increase the activity of a secretion system, strengthen the functions of corresponding organs of the human body, increase the microcirculation regulation of the human body, promote the function enhancement of an immune system and contribute to improving the health and construction efficacy of the human body.
At present, the work and life rhythm of people is fast, the working pressure is high, more and more people are usually in a sub-health state, the body is often in a fatigue state, the fatigue is required to be released, the pressure is relieved, and the pedicure becomes a normal mode for people to select to regulate and relieve the pressure; meanwhile, some old people also select pedicure to promote health care. Foot bath care treatment belongs to one of foot treatment contents in the field of traditional Chinese medicine, and is also a common and commonly used in-vitro treatment method. When people are leisure in life, the hot water is used for bubbling feet, so that the foot bath liquid can relieve fatigue and is beneficial to promoting sleep. If a proper amount of active substances are scientifically and reasonably and effectively blended into the hot water, the pedicure effect can be improved, and the effects of health preservation, health care and the like are effectively improved. In the foot soaking and pedicure process, the key and important health-care mechanism is to promote cells in a foot related region and a response region to make corresponding regulation and meridian activity, strengthen blood circulation, clear away blood garbage and pathological sediment of a human body and play a role in cleaning the human body; simultaneously, the scientific and effective trace active substances enter human cells through the pedicure process and can resist various diseases. Therefore, the foot bath health care is a natural therapy which is simple and easy to implement, remarkable in curative effect and free of toxic and side effects.
Vinasse is residue left after wine making from grain raw materials, and the current research on vinasse is mostly and intensively applied to the aspects of feeds and fertilizers, so that the utilization rate of vinasse resources is low. In addition, although the foot-soaking bags sold in the market also contain traditional Chinese medicines and have a certain curative effect report, the market application shows that the foot-soaking bags still do not solve the problems of treating beriberi, tinea pedis and the like. Therefore, the development of a compound foot-soaking bag with beriberi and tinea pedis treatment function is still an urgent problem to be solved with the main guidance of improving the beriberi and tinea pedis treatment functions of the foot-soaking bag.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides the compound foot-soaking medicine bag containing the active vinasse and the preparation method thereof.
The technical scheme adopted by the invention for solving the technical problem is as follows:
the invention firstly provides a compound foot-soaking medicine bag containing active vinasse, which consists of the following raw materials in parts by weight: 40-50 parts of active vinasse, 3.0-5.0 parts of ginger, 6.5-9.5 parts of dittany bark, 3.0-4.0 parts of dried orange peel, 5.0-8.0 parts of glabrous greenbrier rhizome, 3.0-4.0 parts of lightyellow sophora root, 5.0-7.0 parts of sessile stemona root and 3.0-5.0 parts of Qixingjian tea.
The invention also provides a preparation method of the compound foot-soaking medicine package containing the active vinasse, which comprises the following steps:
the method comprises the following steps: the preparation method of the active vinasse comprises the following specific operations: and (3) distilling fermented grains of the fen-Maotai-flavor liquor for more than 30 days to obtain distiller grains, inoculating the distiller grains with the Cordak ohmeria botrytis, the Korotka ohmeria and the Bacillus amyloliquefaciens, fermenting to obtain distiller grains rich in bioactive components, drying at constant temperature, and keeping the bioactivity of the distiller grains to obtain the active distiller grains.
Step two: uniformly mixing all the raw materials according to the raw material proportion, and drying to obtain a mixed material;
step three: weighing and bagging the dried mixed materials to obtain the compound foot soaking medicine bag.
Preferably, in the step one, the viable bacteria concentration of the saccharomyces cerevisiae inoculated into the vinasse and fermented for 24 hours is kept to be 1.0-2.0 x 10 7 CFU/mL。
Preferably, in the step one, the concentration of viable bacteria of the Korotkoff yeast inoculated into the vinasse and fermented for 24 hours is kept to be 3.0-4.0 x 10 7 CFU/mL。
Preferably, in the step one, the bacillus amyloliquefaciens is inoculated into the vinasse and the concentration of viable bacteria after fermenting for 24 hours is kept to be 2.0-5.0 x 10 7 CFU/mL。
Preferably, the temperature during drying in the step one is 30-45 ℃, and the water content of the active distiller's grains obtained after drying is less than or equal to 13%.
Preferably, before all the raw materials are mixed in the second step, the raw materials are respectively crushed into particles with the particle size of 1-2 mm.
Preferably, the temperature during drying in the second step is 30-45 ℃, and the water content of the mixed material obtained after drying is 12-14% by mass.
Preferably, the weight of the bagged tea in the third step is 10-15 g/bag.
The invention has the following positive effects:
the compound foot-soaking medicine bag is prepared by mixing the vinasse (active vinasse) brewed by the light soy sauce flavor type white spirit fermented by the characteristic microbial strains with the specific traditional Chinese medicine components, and in the process of foot-soaking by using hot water and the medicine bag, rich active compounds can be effectively released in foot-soaking water, so that blood circulation of feet is promoted, beriberi and tinea pedis are treated, muscles and tendons are relaxed, blood circulation is promoted, fatigue is relieved, spleen and stomach are conditioned, sleep quality is improved, and the immune function is adjusted and improved.
Compared with the prior art, the compound foot soaking medicine bag has better foot treatment effect. The invention adopts the characteristic microbial flora to scientifically assemble the fermented active vinasse, and adopts the raw materials of multi-Miao-ethnomedicine traditional Chinese medicinal materials and the like to compound, wherein the active vinasse is metabolized and enriched with a large amount of terpene and phenolic active substances under the fermentation action of the characteristic yeast and bacterial flora, so that the autophagy process can be started by a human body, and cell waste can be removed, thereby achieving the effect of prolonging the life. In addition, the active vinasse also contains 4-5% (V/V) of active alcohols, acetic acid, humic substances, fermentation microbial thallus autolysate and the like, and is also rich in precursor substances with the fragrance of white spirit, such as pyrazine compounds and furan compounds, and the substances have great curative effect and active repairing effect on the skin of a human body, especially for people with beriberi; the active vinasse contains beneficial active functional components, can well stimulate the skin of a human body, is absorbed by the skin, increases the activity of cells on the surface layer of the skin and increases the antibacterial effect, thereby playing the roles of removing beriberi and relieving tinea pedis. Meanwhile, the active vinasse contains rich microorganisms and metabolites thereof, particularly active functional components which are difficult to volatilize, and hematopoietic factors such as calcium, iron and the like, enters human cells through hot water and heat conduction thereof, can enrich the blood, nourish the face, relax the muscles and stimulate the blood circulation, strengthen the body and increase the microcirculation of the human body, is beneficial to the recovery of chronic diseases, can effectively reduce the blood fat and cholesterol, and has certain benefits for preventing cardiovascular and cerebrovascular diseases, so the compound foot soaking medicine bag containing the active vinasse also has the effects of smoothing, glossing, lubricating the skin and the like.
The traditional Chinese medicines such as ginger, dittany bark, dried orange peel, glabrous greenbrier rhizome, lightyellow sophora root, sessile stemona root, Qixingjian and the like have the effect of medicine and food and are special medicinal materials in Miao medicine; the traditional Chinese medicines respectively contain alkaloid, phytosterol, flavonoid, vitamin C, methyl hesperidin, matrine, cytisine and mineral elements such as calcium, magnesium and iron, and the traditional Chinese medicine components and the active vinasse form a unique foot bath bag. Wherein the methyl hesperidin in pericarpium Citri Tangerinae has synergistic effect with vitamin C, and can enhance antibacterial and antiinflammatory effects; radix Sophorae Flavescentis contains matrine and laburnine, and can be used for treating loempe and skin pruritus. Therefore, the Miao medicine formula contained in the patent is different from other vinasse foot soaking bags on the market, and the active vinasse can be used as a traditional Chinese medicine carrier and an active effective embedding body of active functional ingredients, so that the volume storage, the high-efficiency dissolution and the release of the active ingredients of the traditional Chinese medicine are facilitated. Secondly, the active vinasse contains active macromolecular compounds, has curative effect on skin, can generate synergistic effect with the traditional Chinese medicine components, not only enriches the variety and the quantity of substances in the foot bath bag, but also improves the curative effect of the foot bath bag.
The invention focuses on inoculating yeast for producing active functional components such as terpene compounds and bacteria for producing active functional components such as 4-ethylguaiacol to the vinasse of the light soy sauce flavor type white spirit, so that the vinasse is enriched with more active functions and is full, and a compound foot bath bag is developed by combining unique Miao medicament Chinese medicinal materials in Guizhou to treat beriberi, increase the activity of skin cells and improve the curative effect of pedicure. Therefore, the invention provides a compound foot-soaking medicine bag which is prepared by taking active vinasse which is fermented by functional microorganisms and is rich in active functional component compounds as a main carrier and scientifically assisting Chinese herbal medicines with specific efficacy. The compound foot-soaking medicine bag has the advantages of efficiently promoting blood circulation, treating beriberi and tinea pedis, relaxing muscles and tendons, activating blood circulation, promoting qi and blood circulation, relieving fatigue, conditioning spleen and stomach, and improving sleep quality.
Detailed Description
The following is a detailed description of preferred embodiments of the invention.
Example 1
The preferred embodiment 1 of the invention provides a compound foot soaking medicine bag containing active vinasse, which consists of the following raw materials in parts by weight: 45kg of active vinasse, 4.5kg of ginger, 8.5kg of dittany bark, 3.6kg of dried orange peel, 7.2kg of glabrous greenbrier rhizome, 3.6kg of lightyellow sophora root, 6.3kg of sessile stemona root and 4.5kg of Qixingjian.
The embodiment also provides a preparation method of the compound foot-soaking medicine package containing the active vinasse, which comprises the following steps:
the method comprises the following steps: the preparation of the active vinasse comprises the following specific operations: the method comprises the steps of carrying out liquor distillation on fermented grains of the fen-Maotai-flavor liquor for more than 30 days to obtain vinasse, inoculating corynebacterium viticola (Clavispora lusitaniae P.GXZX-2), Kodamaea ohmeri P.FJZP-1 and Bacillus amyloliquefaciens (Bacillus amyloliquefaciens JXDQ-6), fermenting to obtain the vinasse rich in bioactive components, drying at constant temperature of 35 ℃, and keeping the bioactivity of the vinasse to obtain the active vinasse, wherein the mass content of water in the active vinasse is less than or equal to 13%.
Wherein the viable bacteria concentration of the Saccharomyces cerevisiae inoculated into the distiller's grains and fermented for 24 hours is maintained at 1.5 × 10 7 CFU/mL; inoculating Oromkodak yeast into distiller's grains, and fermenting for 24 hr to keep viable bacteria concentration at 3.4 × 10 7 CFU/mL; inoculating Bacillus amyloliquefaciens into distiller's grains, and fermenting for 24 hr to obtain viable bacteria concentration of 3.5 × 10 7 CFU/mL。
Step two: uniformly mixing all the raw materials according to the mixture ratio of the raw materials, and drying at 35 ℃ to obtain a mixed material, wherein the water content is 12% by mass; before all the raw materials are mixed, respectively crushing the raw materials into particles with the particle size distribution of 1-2 mm;
step three: weighing and bagging the dried mixed materials, wherein the bagging weight is 15 g/bag, and thus the compound foot soaking medicine bag is obtained.
Example 2
The preferred embodiment 2 of the invention provides a compound foot-soaking medicine bag containing active vinasse, which consists of the following raw materials in parts by weight: 50kg of active vinasse, 5.0kg of ginger, 9.5kg of dittany bark, 4.0kg of dried orange peel, 8.0kg of glabrous greenbrier rhizome, 4.0kg of lightyellow sophora root, 7.0kg of sessile stemona root and 5.0kg of Qixingjian.
The embodiment also provides a preparation method of the compound foot soaking medicine package containing the active vinasse, which comprises the following steps:
the method comprises the following steps: the preparation of the active vinasse comprises the following specific operations: the method comprises the steps of carrying out liquor distillation on fermented grains of the fen-Maotai-flavor liquor for more than 30 days to obtain vinasse, inoculating corynebacterium viticola (Clavispora lusitaniae P.GXZX-2), Kodamaea ohmeri P.FJZP-1 and Bacillus amyloliquefaciens (Bacillus amyloliquefaciens JXDQ-6), fermenting to obtain the vinasse rich in bioactive components, drying at constant temperature of 40 ℃, and keeping the bioactivity of the vinasse to obtain the active vinasse, wherein the mass content of water in the active vinasse is less than or equal to 13%.
Wherein the viable bacteria concentration of the Saccharomyces cerevisiae inoculated into the distiller's grains and fermented for 24 hours is maintained at 1.0 × 10 7 CFU/mL; inoculating Oromkodak yeast into distiller's grains, and fermenting for 24 hr to keep viable bacteria concentration at 4.0 × 10 7 CFU/mL; inoculating Bacillus amyloliquefaciens into distiller's grains, and fermenting for 24 hr to obtain viable bacteria concentration of 2.0 × 10 7 CFU/mL。
Step two: uniformly mixing all the raw materials according to the raw material proportion, and drying at 40 ℃ to obtain a mixed material, wherein the water content is 14% by mass; before all the raw materials are mixed, respectively crushing the raw materials into particles with the particle size of 1-2 mm;
step three: and weighing and bagging the dried mixed materials, wherein the bagging weight is 10 g/bag, and the compound foot soaking medicine bag is obtained.
Example 3
The preferred embodiment 3 of the invention provides a compound foot soaking medicine bag containing active vinasse, which consists of the following raw materials in parts by weight: 48kg of active vinasse, 4.8kg of ginger, 9.1kg of dittany bark, 3.8kg of dried orange peel, 7.7kg of glabrous greenbrier rhizome, 3.8kg of lightyellow sophora root, 6.7kg of sessile stemona root and 4.8kg of Qixingjian.
The embodiment also provides a preparation method of the compound foot soaking medicine package containing the active vinasse, which comprises the following steps:
the method comprises the following steps: the preparation of the active vinasse comprises the following specific operations: the method comprises the steps of carrying out liquor distillation on fermented grains of the fen-Maotai-flavor liquor for more than 30 days to obtain vinasse, inoculating corynebacterium viticola (Clavispora lusitaniae P.GXZX-2), Kodamaea ohmeri P.FJZP-1 and Bacillus amyloliquefaciens (Bacillus amyloliquefaciens JXDQ-6), fermenting to obtain the vinasse rich in bioactive components, drying at constant temperature of 30 ℃, and keeping the bioactivity of the vinasse to obtain the active vinasse, wherein the mass content of water in the active vinasse is less than or equal to 13%.
Wherein the viable bacteria concentration of the Saccharomyces cerevisiae inoculated into the distiller's grains and fermented for 24 hours is kept at 2.0 × 10 7 CFU/mL; adding yeast kodak into distiller's grains and fermentingThe viable bacteria concentration after fermenting for 24 hours is kept at 3.0X 10 7 CFU/mL; inoculating Bacillus amyloliquefaciens into distiller's grains, and fermenting for 24 hr to obtain viable bacteria concentration of 5.0 × 10 7 CFU/mL。
Step two: uniformly mixing all the raw materials according to the raw material proportion, and drying at 30 ℃ to obtain a mixed material, wherein the water content is 13% by mass; before all the raw materials are mixed, respectively crushing the raw materials into particles with the particle size of 1-2 mm;
step three: and weighing and bagging the dried mixed materials, wherein the bagging weight is 12 g/bag, and the compound foot soaking medicine bag is obtained.
Comparative example 1
The comparative example 1 provides a compound foot bath medicine bag which is composed of the following raw materials in parts by weight: 5.0kg of ginger, 9.5kg of dittany bark, 4.0kg of dried orange peel, 8.0kg of glabrous greenbrier rhizome, 4.0kg of lightyellow sophora root, 7.0kg of sessile stemona root and 5.0kg of Qixingjian.
The embodiment also provides a preparation method of the compound foot soaking medicine bag, which comprises the following steps:
the method comprises the following steps: uniformly mixing all the raw materials according to the raw material proportion, and drying at 40 ℃ to obtain a mixed material, wherein the water content is 14% by mass; before all the raw materials are mixed, respectively crushing the raw materials into particles with the particle size of 1-2 mm;
step two: weighing and bagging the dried mixed materials, wherein the bagging weight is 10 g/bag, and the compound foot soaking medicine bag is obtained.
Comparative example 2
The comparative example 2 provides an active lees foot bath medicine bag, and the preparation method comprises the following steps:
the method comprises the following steps: the preparation method of the active vinasse comprises the following specific operations: the method comprises the steps of carrying out liquor distillation on fermented grains of the fen-Maotai-flavor liquor for more than 30 days to obtain vinasse, inoculating corynebacterium viticola (Clavispora lusitaniae P.GXZX-2), Kodamaea ohmeri P.FJZP-1 and Bacillus amyloliquefaciens (Bacillus amyloliquefaciens JXDQ-6), fermenting to obtain the vinasse rich in bioactive components, drying at constant temperature of 40 ℃, and keeping the bioactivity of the vinasse to obtain the active vinasse, wherein the mass content of water in the active vinasse is less than or equal to 13%.
Wherein, the concentration of viable bacteria after the saccharomyces cerevisiae is inoculated into the vinasse and fermented for 24 hours is kept to be 1.0 multiplied by 107 CFU/mL; inoculating the Oromkodak yeast into vinasse, and keeping the concentration of viable bacteria at 4.0 x 107CFU/mL after fermenting for 24 hours; the viable bacteria concentration of the bacillus amyloliquefaciens inoculated into the vinasse and fermented for 24 hours is kept to be 2.0 x 107 CFU/mL.
Step two: crushing the dried active vinasse into particles with the particle size of 1-2 mm;
step three: weighing and bagging the active vinasse, wherein the bagging weight is 10 g/bag, and thus the active vinasse foot soaking medicine bag is obtained.
Effect test
The using method comprises the following steps:
(1) putting the corresponding foot soaking medicine bag into a basin, adding 100 times of purified water with the temperature of 80 ℃, and continuously stirring;
(2) soaking feet in the pedicure foot soaking bag medicinal water for 40 min after the water temperature is reduced to 45 deg.C, and controlling the water temperature at 35-45 deg.C;
(3) the foot bath bag is used 1 time per day, 2 foot bath bags are used in each treatment course, and foot therapy is continuously carried out for 7 days.
The test method comprises the following steps:
100 patients are randomly selected from the groups of example 1, example 2, example 3, comparative example 1 and comparative example 2 for trial, and effective rate statistics is respectively carried out on various symptoms contained in each group of patients after the treatment course is finished. The test results are shown in the following table:
Figure BDA0003718434320000091
clinical cases:
in case 1, the body constitution is wet and cold, the hands and feet are cold all the year round and often feel cold, and after the product obtained in the embodiment 2 of the invention is continuously used for 12 days, qi and blood are smooth, the cold dampness in the body is completely removed, the cold symptoms of the hands and the feet are avoided, the immunity is improved, the sleep quality is improved, the physical strength is restored, the mood is full, and the body is light and healthy.
In case 2, the patient is weak in constitution and often feels unable to breathe with exercise, and the product obtained in the embodiment 2 of the invention is red in qi and blood after being continuously used for 15 days, does not feel labored during exercise, improves immunity, improves sleep quality, recovers physical strength, is full in mood, and is light and healthy.
In case 3, the foot odor and the beriberi are severe, and the feet often sweat and peel, and after the product obtained in the embodiment 2 of the invention is continuously used for 7 days, the symptoms of the beriberi are obviously improved, the dead skin on the feet is obviously removed, the beriberi is also obviously removed, and the phenomenon of the foot odor is avoided.
The above embodiments are only preferred embodiments of the present invention, and it should be understood that the above embodiments are only for assisting understanding of the method and the core idea of the present invention, and are not intended to limit the scope of the present invention, and any modifications, equivalents and the like made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims (9)

1. The compound foot-soaking medicine bag containing active vinasse is characterized by comprising the following raw materials in parts by weight: 40-50 parts of active vinasse, 3.0-5.0 parts of ginger, 6.5-9.5 parts of dittany bark, 3.0-4.0 parts of dried orange peel, 5.0-8.0 parts of glabrous greenbrier rhizome, 3.0-4.0 parts of lightyellow sophora root, 5.0-7.0 parts of sessile stemona root and 3.0-5.0 parts of Qixingjian tea.
2. A preparation method of a compound foot-soaking medicine package containing active vinasse is characterized by comprising the following steps:
the method comprises the following steps: the preparation method of the active vinasse comprises the following specific operations: and (3) distilling fermented grains of the fen-Maotai-flavor liquor for more than 30 days to obtain distiller grains, inoculating the distiller grains with the Cordak ohmeria botrytis, the Korotka ohmeria and the Bacillus amyloliquefaciens, fermenting to obtain distiller grains rich in bioactive components, drying at constant temperature, and keeping the bioactivity of the distiller grains to obtain the active distiller grains.
Step two: uniformly mixing all the raw materials according to the raw material proportion in claim 1, and drying to obtain a mixed material;
step three: weighing and bagging the dried mixed materials to obtain the compound foot soaking medicine bag.
3. The method of claim 2, wherein the method comprises the steps of: in the first step, the saccharomyces cerevisiae is inoculated into vinasse and the concentration of viable bacteria after 24 hours of fermentation is kept to be 1.0-2.0 multiplied by 10 7 CFU/mL。
4. The method of claim 2, wherein the method comprises the steps of: in the first step, the Korotka ohmer yeast is inoculated into the vinasse and the viable bacteria concentration after 24 hours of fermentation is kept to be 3.0-4.0 multiplied by 10 7 CFU/mL。
5. The method of claim 2, wherein the method comprises the steps of: in the first step, the bacillus amyloliquefaciens is inoculated into vinasse and the concentration of viable bacteria after fermentation for 24 hours is kept to be 2.0-5.0 multiplied by 10 7 CFU/mL。
6. The method of claim 2, wherein the method comprises the steps of: the temperature during drying in the step one is 30-45 ℃, and the water content of the active vinasse obtained after drying is less than or equal to 13% by mass.
7. The method of claim 2, wherein the method comprises the steps of: and in the second step, all the raw materials are respectively crushed into particles with the particle size of 1-2 mm before being mixed.
8. The method of claim 2, wherein the method comprises the steps of: and in the second step, the temperature during drying is 30-45 ℃, and the water content of the mixed material obtained after drying is 12-14% by mass.
9. The method of claim 2, wherein the method comprises the steps of: the weight of the bagged tea in the third step is 10-15 g per bag.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101744973A (en) * 2008-12-17 2010-06-23 宜宾学院 Chinese medicinal extractum and extraction process thereof
CN103316260A (en) * 2013-05-06 2013-09-25 重庆市中药研究院 Massage cream for treating tinea of hands and feet
CN111035750A (en) * 2020-01-14 2020-04-21 泸州金窖醇酒业有限公司 A foot bath medicinal bag prepared from distiller's grains and Chinese medicinal materials

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101744973A (en) * 2008-12-17 2010-06-23 宜宾学院 Chinese medicinal extractum and extraction process thereof
CN103316260A (en) * 2013-05-06 2013-09-25 重庆市中药研究院 Massage cream for treating tinea of hands and feet
CN111035750A (en) * 2020-01-14 2020-04-21 泸州金窖醇酒业有限公司 A foot bath medicinal bag prepared from distiller's grains and Chinese medicinal materials

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
刘玺;: "洗剂加外涂治疗湿疹152例" *
王敬敏;: "中西药外用治疗老年性***炎" *
白美蓉;陈前明;廖建芬;: "药物联合中药薰蒸治疗瘙痒症36例疗效观察" *

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