CN1147816A - 17β-氰基-3-乙氧基-17α-羟基-6-甲基雄甾-3，5，9(11)-三烯的合成 - Google Patents

17β-氰基-3-乙氧基-17α-羟基-6-甲基雄甾-3，5，9(11)-三烯的合成 Download PDF

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Publication number
CN1147816A
CN1147816A CN95192975A CN95192975A CN1147816A CN 1147816 A CN1147816 A CN 1147816A CN 95192975 A CN95192975 A CN 95192975A CN 95192975 A CN95192975 A CN 95192975A CN 1147816 A CN1147816 A CN 1147816A
Authority
CN
China
Prior art keywords
alpha
beta
cyanos
methyl
triolefin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95192975A
Other languages
English (en)
Chinese (zh)
Inventor
J·G·雷德
T·德彼克-克洛克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of CN1147816A publication Critical patent/CN1147816A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN95192975A 1994-05-09 1995-05-02 17β-氰基-3-乙氧基-17α-羟基-6-甲基雄甾-3，5，9(11)-三烯的合成 Pending CN1147816A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24003694A 1994-05-09 1994-05-09
US08/240,036 1994-05-09

Publications (1)

Publication Number Publication Date
CN1147816A true CN1147816A (zh) 1997-04-16

Family

ID=22904843

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95192975A Pending CN1147816A (zh) 1994-05-09 1995-05-02 17β-氰基-3-乙氧基-17α-羟基-6-甲基雄甾-3，5，9(11)-三烯的合成

Country Status (9)

Country Link
EP (1) EP0759928A1 (ko)
JP (1) JPH10500946A (ko)
KR (1) KR970702873A (ko)
CN (1) CN1147816A (ko)
AU (1) AU684946B2 (ko)
CA (1) CA2187522A1 (ko)
HU (1) HUT75517A (ko)
MX (1) MX9605428A (ko)
WO (1) WO1995030684A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112898365A (zh) * 2021-03-08 2021-06-04 营口德瑞化工有限公司 一种17β-氰基-17α-羟基雄甾-4-烯-3-酮的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2468617A1 (fr) * 1979-10-26 1981-05-08 Roussel Uclaf Nouveaux derives acetyleniques chlores de l'androst-4-ene leur procede de preparation, et leur application a titre de medicament et les compositions pharmaceutiques les renfermant
DE3585547D1 (de) * 1984-02-03 1992-04-16 Upjohn Co Steroide mit einer enamid- oder enimidgruppe sowie ihre herstellung.
DE3427486A1 (de) * 1984-07-23 1986-01-30 Schering AG, Berlin und Bergkamen, 1000 Berlin Verfahren zur herstellung von 6(alpha)-methylsteroiden
DE3434448A1 (de) * 1984-09-17 1986-03-27 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von pregnan-derivaten
DD281394A5 (de) * 1984-12-10 1990-08-08 Jenapharm Veb Verfahren zur herstellung von steroid-c-17 alpha-carbonitrilen
WO1988002753A2 (en) * 1986-10-10 1988-04-21 Gist-Brocades N.V. 9-alpha-hydroxy steroids and process for their preparation
CA1317283C (en) * 1986-11-05 1993-05-04 Douglas Alan Livingston Steroidal 17–-silyl ethers and process to corticoids and progesterones

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112898365A (zh) * 2021-03-08 2021-06-04 营口德瑞化工有限公司 一种17β-氰基-17α-羟基雄甾-4-烯-3-酮的合成方法
CN112898365B (zh) * 2021-03-08 2023-02-28 营口德瑞化工有限公司 一种17β-氰基-17α-羟基雄甾-4-烯-3-酮的合成方法

Also Published As

Publication number Publication date
MX9605428A (es) 1997-12-31
HU9603110D0 (en) 1997-01-28
EP0759928A1 (en) 1997-03-05
KR970702873A (ko) 1997-06-10
AU2362895A (en) 1995-11-29
CA2187522A1 (en) 1995-11-16
JPH10500946A (ja) 1998-01-27
HUT75517A (en) 1997-05-28
AU684946B2 (en) 1998-01-08
WO1995030684A1 (en) 1995-11-16

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication