CN114748593B - Medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid and preparation method thereof - Google Patents

Medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid and preparation method thereof Download PDF

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CN114748593B
CN114748593B CN202210534315.9A CN202210534315A CN114748593B CN 114748593 B CN114748593 B CN 114748593B CN 202210534315 A CN202210534315 A CN 202210534315A CN 114748593 B CN114748593 B CN 114748593B
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栗明峰
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract

The invention belongs to the technical field of traditional Chinese medicines, in particular to a twenty-ingredient fructus alpiniae oxyphyllae liquid with homology of medicine and food and a preparation method thereof.

Description

Medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid and a preparation method thereof.
Background
The weakness of the spleen and the stomach of the children is mainly manifested by no blood color, emaciation, constipation or diarrhea, poor appetite, gastric and abdominal distention, inappetence, vigorous lung fire, repeated upper respiratory tract infection and the like after a little more eating. Weakness of the spleen and stomach in children is usually caused by congenital deficiency or acquired malnutrition. Among them, the congenital reasons include premature birth of children, weakness of spleen and stomach of parents, etc.; acquired reasons include food and drink, such as cold and greasy eating, improper feeding, food accumulation and the like; in addition, some children have not timely conditioned their abdomen after suffering from other diseases, and a series of diseases of weak spleen and stomach can also result.
At present, the disease symptoms of the children such as stomach deficiency and spleen weakness can be generally conditioned through physical physiotherapy methods such as Chinese patent medicines, massage, moxibustion and the like, but the inventor finds that the existing treatment method is over single in curative effect and poor in curative effect in general in the field of medical science, and in addition, the acceptance of the children in the age range needs to be fully considered for the children, so that the adverse effects of the medicines on the children need to be reduced or avoided as much as possible.
Disclosure of Invention
The application aims to provide a medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid and a preparation method thereof, and solves the technical problems that the treatment effect for the spleen and stomach weakness of children is poor, and especially for children suffering from the age of 5 years or older, the treatment effect cannot be ensured while the reduction of side effects is considered.
The application provides a doctor in the department of pediatrics, in the east Tian Zhangcun of the city of Henan province, which is specially used for pediatrics, and mainly treats the pediatric diseases including weakness of the spleen and the stomach, repeated illness due to low resistance and the like of the children, and takes care of a great deal of cases of the children with weakness of the spleen and the stomach for many years.
In the long-term diagnosis and treatment process, the inventor finds that the traditional Chinese patent medicines, the traditional physiotherapy such as massage and moxibustion and the like have single treatment effect on the diseases of the children caused by the deficiency of the stomach and the weakness of the spleen, and especially have poor treatment effect on sequelae caused by the deficiency of the spleen and the weakness of the stomach.
In addition, the gastrointestinal functions and physical conditions of children under 5 years old and children over 5 years old are generally obviously different, the national standard of the 'determination of growth condition of children under 5 years old' is also issued, and the dosage and prescription of expected curative effect need to be considered for the height, weight and absorption capacity of children over 5 years old, and the side effect on children suffering from the age group needs to be sufficiently considered.
Therefore, by combining clinical experience and traditional Chinese medicine theory, the inventor develops a traditional Chinese medicine liquid capable of effectively regulating the spleen and stomach weakness of children, namely twenty kinds of fructus alpiniae oxyphyllae liquid with homology of medicine and food, and the liquid medicine can achieve good treatment effect while reducing side effects on children over 5 years old.
The first aspect of the invention is:
the medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid is prepared by decocting a traditional Chinese medicine composition and a maltose auxiliary material, wherein the traditional Chinese medicine composition comprises, by weight, 450-550 parts of dark plum fruit, 350-450 parts of Chinese yam, 350-450 parts of hawthorn fruit, 350-450 parts of malt, 450-550 parts of Chinese date, 450-550 parts of poria cocos, 350-450 parts of coix seed, 350-450 parts of dwarf lilyturf tuber, 350-450 parts of dried orange peel, 350-450 parts of fragrant solomonseal rhizome, 550-650 parts of longan pulp, 350-450 parts of radish seed, 350-450 parts of sweet almond, 350-450 parts of sea buckthorn, 550-650 parts of bunge cherry seed, 450-550 parts of mulberry fruit, 550-650 parts of fructus alpiniae oxyphyllae, 550-650 parts of lotus leaf, 450-550 parts of rhizoma polygonati officinalis and 550-650 parts of pagodatree flower bud.
Preferably, the traditional Chinese medicine composition comprises 500 parts of dark plum, 400 parts of Chinese yam, 400 parts of hawthorn, 400 parts of malt, 500 parts of jujube, 500 parts of poria cocos, 400 parts of coix seed, 400 parts of dwarf lilyturf tuber, 400 parts of dried orange peel, 400 parts of fragrant solomonseal rhizome, 600 parts of longan pulp, 400 parts of radish seed, 400 parts of sweet almond, 400 parts of sea buckthorn, 600 parts of bunge cherry seed, 500 parts of mulberry, 600 parts of fructus alpiniae oxyphyllae, 600 parts of lotus leaf, 500 parts of rhizoma polygonati and 600 parts of pagodatree flower bud.
The second aspect of the invention is:
the invention provides a preparation method of a medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid, which comprises the following steps:
(1) Preparing a liquid medicine:
(1.1) preparation of monarch drug liquid: preparing monarch drug liquid medicine from dark plum, jujube, poria cocos, mulberry and rhizoma polygonati in a monarch drug formula in the traditional Chinese medicine composition;
(1.2) preparation of ministerial drug liquid: taking ministerial drug liquid from Chinese yam, dwarf lilyturf tuber, dried orange peel and rhizoma polygonati in a ministerial drug formula in the traditional Chinese medicine composition;
(1.3) preparation of adjuvant drug liquid: preparing adjuvant medicinal liquid from fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum and fructus Hippophae;
(1.4) preparation of a medicinal liquid: the preparation method comprises preparing medicinal liquid from arillus longan, semen Pruni, fructus Alpinae Oxyphyllae, folium Nelumbinis and flos Sophorae Immaturus in the medicinal formula;
(2) The monarch drug liquid medicine, ministerial drug liquid medicine, adjuvant drug liquid medicine and messenger drug liquid medicine prepared in the step (1) are placed in a shade place for standing for a period of time for standby;
(3) Mixing the monarch drug liquid, ministerial drug liquid, adjuvant drug liquid and guide drug liquid which are kept stand for standby in the step (2) together, adding a proper amount of maltose, decocting with small fire, continuously stirring and uniformly stirring, and then closing the fire, discharging from a pot and filling into a medical medicine bottle.
Preferably, the preparation of the monarch drug liquid medicine specifically comprises the following steps:
(1.1.1) soaking: cutting dark plum, jujube, poria cocos, mulberry and rhizoma polygonati in a monarch drug formula in a traditional Chinese medicine composition, cleaning, putting into a decoction pot, adding 7500-8500 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.1.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.1.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
Preferably, the preparation of the ministerial drug liquid specifically comprises:
(1.2.1) soaking: cutting and cleaning Chinese yam, dwarf lilyturf tuber, dried orange peel and fragrant solomonseal rhizome in a ministerial drug formula in the traditional Chinese medicine composition, putting the crushed and cleaned Chinese yam, dwarf lilyturf tuber, dried orange peel and fragrant solomonseal rhizome into a decoction pot, adding 9100-11000 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.2.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.2.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
Preferably, the preparation of the adjuvant drug liquid specifically comprises:
(1.3.1) soaking: cutting hawthorns, malt, coix seeds, radish seeds, sweet almonds and sea-buckthorn in an adjuvant prescription in the traditional Chinese medicine composition, cleaning, putting into a decoction pot, adding 7500-8500 parts of cold water according to the same weight parts as the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.3.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.3.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
Preferably, the preparation of the drug solution specifically comprises:
(1.4.1) soaking: cutting longan pulp, bunge cherry seed, fructus alpiniae oxyphyllae, lotus leaf and pagodatree flower bud in a traditional Chinese medicine composition, cleaning, putting into a decoction pot, adding 11500-12500 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.4.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.4.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
In the development process of the medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid, the inventor mainly uses the medicinal and edible Chinese medicine theory, and the components in the medicinal and edible formula can be used as food and Chinese medicinal materials with therapeutic effect, so that the medicinal and edible Chinese medicinal formula is safer than the pure Chinese medicinal formula, has small side effect and is suitable for children.
Chinese traditional medicine has since ancient times had a theory of "homology of medicine and food" (also known as "homology of medicine and food"), which is believed to be: many foods are foods and medicines, many foods can be used as medicines, and many medicines can be eaten, so that strict distinction between the foods and the medicines is difficult, and the food is the basis of the theory of homology of medicine and food and the basis of food therapy. Among them, the "Neijing" has very excellent theory for diet therapy, such as "treating diseases with toxic materials, removing six of them; treating diseases with frequent toxins, ten times removing seven times; treating diseases with little toxin, and removing eight of the diseases; nontoxic cure, ten times to nine times; the cereal, meat, fruit and vegetable are eaten completely, and the food is not used, so that the healthy energy of the cereal is impaired, which can be called as the earliest food therapy principle.
The concept of a traditional Chinese medicine is as follows: all Chinese medicines can be eaten only by a difference in dosage, that is, the dosage with large toxic effect is small, and the dosage with small toxic effect is large. Thus, strictly speaking, in traditional Chinese medicine, medicines and foods are indiscriminate, and are relatively speaking, medicines are foods, and foods are medicines; the side effect of food is small, and the side effect of medicine is large, which is another meaning of 'homology of medicine and food'.
The pharmacological analysis of each component in the traditional Chinese medicine composition used by the twenty-ingredient fructus alpiniae oxyphyllae liquid with homology of medicine and food is as follows:
dark plum: has effects of astringing lung and promoting fluid production. It is used for treating chronic cough due to lung deficiency, chronic diarrhea, chronic dysentery, deficiency heat, diabetes, emesis, and abdominal pain due to ascariasis.
Chinese yam: tonifying spleen and stomach, promoting fluid production and tonifying lung, tonifying kidney and astringing essence. Is used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, asthma, cough, deficiency heat, and diabetes.
Poria cocos: induce diuresis and excrete dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm retention, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Dried orange peel: regulate qi, invigorate spleen, dry dampness and resolve phlegm. Can be used for treating fullness in chest and epigastrium, anorexia, vomiting and diarrhea, cough with excessive phlegm.
Jujube: tonify middle energizer, replenish qi, nourish blood and tranquilize mind. It is used for treating spleen deficiency, anorexia, debilitation, and loose stool.
Semen Coicis: invigorating spleen, eliminating dampness, removing arthralgia, relieving diarrhea, clearing heat and expelling strong. Can be used for treating edema, tinea pedis, dysuria, spasm of arthralgia due to dampness, diarrhea due to spleen deficiency, pulmonary abscess, appendicitis, and flat wart.
Radix Ophiopogonis: nourishing yin, promoting salivation, moistening lung, and clearing away heart-fire. Can be used for treating dry cough due to lung dryness. Cough due to deficiency of both the body fluid and the head, polydipsia, vexation, insomnia, internal heat, diabetes, constipation due to intestinal dryness, and diphtheria.
Hawthorn fruit: promoting digestion, invigorating stomach, promoting qi circulation, and dispelling blood stasis. Can be used for treating food stagnation, gastric distention, diarrhea, abdominal pain, blood stasis amenorrhea, puerperal blood stasis, thoracalgia, and hernia pain; hyperlipidemia. The food-digesting and stagnation-removing effects of the charred fructus crataegi are enhanced. It can be used for treating food stagnation and diarrhea.
Malt (stir-fried): promoting qi circulation, resolving food stagnation, invigorating spleen, stimulating appetite, promoting lactation and relieving distention.
Polygonatum odoratum (L.) Ohwi: nourishing yin, moistening dryness, relieving restlessness, and quenching thirst. Can be used for treating yin injury due to heat disease, cough, polydipsia, consumptive disease, fever, gu Yiji, and frequent urination.
Longan: sweet, flat and nontoxic. The main pathogenic factors of the five zang organs, calming the mind, relieving anorexia, removing insects and toxins. The patient takes the Chinese medicine for a long time to strengthen soul, improve intelligence, lighten the body, and promote the mind.
Radish seed: promote digestion and remove distention, reduce qi and resolve phlegm. Can be used for treating food stagnation, abdominal distention and pain, constipation, diarrhea due to accumulation of food stagnation, phlegm accumulation, asthma and cough.
Sweet almond: enter the large intestine channel of lung, dispel phlegm, relieve cough, relieve asthma and moisten the intestines. Can be used for treating cough, asthma, pharyngitis, constipation due to intestinal dryness.
Sea buckthorn: cough relieving, phlegm eliminating, digestion promoting, stagnation resolving, blood circulation promoting, and blood stasis dispelling effects. Can be used for treating cough, excessive phlegm, dyspepsia, and abdominal pain.
Semen Pruni: enter spleen and large intestine and small intestine meridians, moisten dryness and smooth intestine, and promote diuresis. Can be used for treating dry and dry body fluid, food stagnation, abdominal distention, constipation, edema, tinea pedis, and dysuria.
Mulberry: it has effects in nourishing heart, liver and kidney channels, replenishing blood, nourishing yin, promoting salivation, and moistening dryness. Can be used for treating giddiness, tinnitus, palpitation, insomnia, body fluid deficiency, thirst, internal heat, diabetes, and constipation due to blood deficiency.
Fructus alpiniae oxyphyllae: enters spleen and kidney channels, warms spleen and warms kidney and secures qi. Can be used for treating cold abdominal pain, middle-jiao vomiting and diarrhea, excessive saliva, and dribbling urine.
Lotus leaf: it has effects in invigorating liver, spleen and kidney, clearing away summer heat, promoting hair growth, clearing yang, cooling blood, and stopping bleeding. Can be used for treating summer heat, polydipsia, summer heat, diarrhea, spleen deficiency diarrhea, hematemesis, hematochezia, metrorrhagia, and metrostaxis.
Rhizoma polygonati: the Chinese medicinal composition has the effects of invigorating spleen, lung and kidney channels, tonifying qi, nourishing yin, invigorating spleen, moistening lung and tonifying kidney. Can be used for treating weakness of spleen and stomach, tiredness, debilitation, dry mouth, anorexia, cough due to lung deficiency, essence and blood deficiency, and internal heat diabetes.
Pagodatree flower bud: cool blood, stop bleeding, clear liver and purge fire. Can be used for treating hematochezia, hemorrhoid, bloody dysentery, hematemesis, epistaxis, liver heat, conjunctival congestion, headache, and dizziness.
Compared with the prior art, the invention has the beneficial effects that:
1. the medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, is suitable for conditioning spleen and stomach weakness of children in the age group of 5 years and sequelae caused by the spleen and lung tonifying effect, can achieve double conditioning, can be used for conditioning the congenital spleen and stomach deficiency of children, repeated constipation, diarrhea, dyspepsia, malabsorption and repeated upper respiratory tract infection caused by the acquired spleen and stomach weakness, and has good conditioning effect on the sequelae (pharyngitis, tonsil hypertrophy, adenoid hypertrophy, allergic rhinitis and allergic tracheitis).
2. The invention relates to a medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid, which is prepared from twenty medicinal and edible raw materials including dark plum, chinese yam, hawthorn, malt, chinese date, poria cocos, coix seed, dwarf lilyturf tuber, dried orange peel, fragrant solomonseal rhizome, dried longan pulp, radish seed, sweet almond, sea buckthorn, bunge cherry seed, mulberry, fructus alpiniae oxyphyllae, lotus leaf, rhizoma polygonati and pagodatree flower bud. The medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid has good taste and is easy to accept by children.
3. Considering the characteristics of relatively good gastrointestinal functions and absorption capacity of children over 5 years old, the medicine is not concentrated into ointment, but is directly prepared into liquid medicine, so that the medicine cost is reduced, and clinical application shows that the medicine has good treatment effect on spleen and stomach weakness symptoms and induced sequelae of children over 5 years old.
Detailed Description
The present invention will be described in detail with reference to the following examples, in which the parts not identified with specific conditions are carried out under conventional conditions or conditions suggested by the manufacturer, and reagents or instruments used are conventional products available commercially without identifying the manufacturer. In addition, 1 part in the following examples is 1g.
Example 1:
the implementation provides a medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid, which is prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises, by weight, 450 parts of dark plum fruit, 350 parts of Chinese yam, 350 parts of hawthorn fruit, 350 parts of malt, 450 parts of jujube, 450 parts of poria cocos, 350 parts of coix seed, 350 parts of dwarf lilyturf tuber, 350 parts of dried orange peel, 350 parts of fragrant solomonseal rhizome, 550 parts of longan pulp, 350 parts of radish seed, 350 parts of sweet almond, 350 parts of sea buckthorn, 550 parts of bunge cherry seed, 450 parts of mulberry, 550 parts of fructus alpiniae oxyphyllae, 550 parts of lotus leaf, 450 parts of rhizoma polygonati and 550 parts of pagodatree flower bud.
The preparation method of the medicine-food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid comprises the following steps:
(1) Preparing a liquid medicine:
(1.1) preparation of monarch drug liquid: the monarch drug liquid medicine is prepared from dark plum, jujube, tuckahoe, mulberry and rhizoma polygonati in a monarch drug formula in the traditional Chinese medicine composition.
The preparation of the monarch drug liquid medicine specifically comprises the following steps:
(1.1.1) soaking: the dark plum, the jujube, the poria cocos, the mulberry and the rhizoma polygonati in the monarch drug formula in the traditional Chinese medicine composition are chopped and cleaned, then put into a decoction pot, added with 7500 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaked for 10 hours.
(1.1.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.1.3) combining the decocted liquid medicine, precipitating, and filtering with four layers of gauze for three times to further remove impurities in the liquid medicine.
(1.2) preparation of ministerial drug liquid: the ministerial drug liquid is taken by Chinese yam, dwarf lilyturf tuber, dried orange peel and bamboo in a ministerial drug formula in the traditional Chinese medicine composition.
The preparation of ministerial drug liquid comprises the following steps:
(1.2.1) soaking: cutting and cleaning Chinese yam, dwarf lilyturf tuber, dried orange peel and fragrant solomonseal rhizome in a ministerial drug formula in the traditional Chinese medicine composition, putting the mixture into a decoction pot, adding 9100 parts of cold water according to the same parts by weight as the traditional Chinese medicine composition, and soaking for 10 hours.
(1.2.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; and (3) performing third decoction according to the same method as the second decoction, and then filtering to take out the liquid medicine.
(1.2.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(1.3) preparation of adjuvant drug liquid: the adjuvant medicinal liquid is prepared from fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum and fructus Hippophae.
The preparation of the adjuvant medicine liquid specifically comprises the following steps:
(1.3.1) soaking: cutting fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum, and fructus Hippophae, cleaning, placing into a decocting pot, adding 7500 parts of cold water, and soaking for 10 hr.
(1.3.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; and (3) performing third decoction according to the same method as the second decoction, and then filtering to take out the liquid medicine.
(1.3.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(1.4) preparation of a medicinal liquid: the Chinese medicinal liquid is prepared from arillus longan, semen Pruni, fructus Alpinae Oxyphyllae, folium Nelumbinis, and fructus Sophorae in the Chinese medicinal composition.
The preparation of the medicine liquid specifically comprises the following steps:
(1.4.1) soaking: the longan pulp, the bunge cherry seed, the fructus alpiniae oxyphyllae, the lotus leaf and the pagodatree flower bud in the traditional Chinese medicine composition are chopped and cleaned, then put into a decoction pot, added with 11500 parts of cold water according to the same weight parts as the traditional Chinese medicine composition, and soaked for 10 hours.
(1.4.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.4.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(2) The monarch drug liquid medicine, ministerial drug liquid medicine, adjuvant drug liquid medicine and messenger drug liquid medicine prepared in the step (1) are placed in a shade place for standing for a period of time for standby. Standing for 5 to 8 days.
(3) Mixing the monarch drug liquid, ministerial drug liquid, adjuvant drug liquid and guide drug liquid which are kept stand for standby in the step (2) together, adding a proper amount of maltose, decocting with small fire, continuously stirring and uniformly stirring, and then closing the fire, discharging from a pot and filling into a medical medicine bottle.
The added maltose mainly improves the taste, so that the ointment is suitable for children to take, and meanwhile, the maltose also has the effects of tonifying spleen and replenishing qi. Here, if a vial is enclosed, 6ml per vial is enclosed; and when the big bottle is packaged, scale marks are arranged in the bottle cover, so that the medicine consumption can be mastered during taking.
Example 2:
the embodiment provides a medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid, which comprises, by weight, 500 parts of dark plum fruit, 400 parts of Chinese yam, 400 parts of hawthorn fruit, 400 parts of malt, 500 parts of Chinese date, 500 parts of poria cocos, 400 parts of coix seed, 400 parts of dwarf lilyturf tuber, 400 parts of dried orange peel, 400 parts of fragrant solomonseal rhizome, 600 parts of longan pulp, 400 parts of radish seed, 400 parts of sweet almond, 400 parts of sea buckthorn, 600 parts of bunge cherry seed, 500 parts of mulberry, 600 parts of fructus alpiniae oxyphyllae, 600 parts of lotus leaf, 500 parts of rhizoma polygonati and 600 parts of pagodatree flower bud.
The preparation method of the medicine-food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid comprises the following steps:
(1) Preparing a liquid medicine:
(1.1) preparation of monarch drug liquid: the monarch drug liquid medicine is prepared from dark plum, jujube, tuckahoe, mulberry and rhizoma polygonati in a monarch drug formula in the traditional Chinese medicine composition.
The preparation of the monarch drug liquid medicine specifically comprises the following steps:
(1.1.1) soaking: the dark plum, the jujube, the poria cocos, the mulberry and the rhizoma polygonati in the monarch drug formula in the traditional Chinese medicine composition are chopped and cleaned, then put into a decoction pot, and added with 8000 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaked for 12 hours.
(1.1.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.1.3) combining the decocted liquid medicine, precipitating, and filtering with four layers of gauze for three times to further remove impurities in the liquid medicine.
(1.2) preparation of ministerial drug liquid: the ministerial drug liquid is taken by Chinese yam, dwarf lilyturf tuber, dried orange peel and bamboo in a ministerial drug formula in the traditional Chinese medicine composition.
The preparation of ministerial drug liquid comprises the following steps:
(1.2.1) soaking: cutting and cleaning Chinese yam, dwarf lilyturf tuber, dried orange peel and fragrant solomonseal rhizome in a ministerial drug formula in the traditional Chinese medicine composition, putting into a decoction pot, adding 9600 parts of cold water according to the same parts by weight as the traditional Chinese medicine composition, and soaking for 12 hours.
(1.2.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; and (3) performing third decoction according to the same method as the second decoction, and then filtering to take out the liquid medicine.
(1.2.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(1.3) preparation of adjuvant drug liquid: the adjuvant medicinal liquid is prepared from fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum and fructus Hippophae.
The preparation of the adjuvant medicine liquid specifically comprises the following steps:
(1.3.1) soaking: cutting fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum, and fructus Hippophae, cleaning, placing into a decocting pot, adding 8000 parts of cold water, and soaking for 12 hr.
(1.3.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; and (3) performing third decoction according to the same method as the second decoction, and then filtering to take out the liquid medicine.
(1.3.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(1.4) preparation of a medicinal liquid: the Chinese medicinal liquid is prepared from arillus longan, semen Pruni, fructus Alpinae Oxyphyllae, folium Nelumbinis, and fructus Sophorae in the Chinese medicinal composition.
The preparation of the medicine liquid specifically comprises the following steps:
(1.4.1) soaking: the longan pulp, the bunge cherry seed, the fructus alpiniae oxyphyllae, the lotus leaf and the flos sophorae in the traditional Chinese medicine composition are chopped and cleaned, then put into a decoction pot, and added with 12000 parts of cold water according to the same weight parts as the traditional Chinese medicine composition, and soaked for 12 hours.
(1.4.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.4.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(2) The monarch drug liquid medicine, ministerial drug liquid medicine, adjuvant drug liquid medicine and messenger drug liquid medicine prepared in the step (1) are placed in a shade place for standing for a period of time for standby. Standing for 5 to 8 days.
(3) Mixing the monarch drug liquid, ministerial drug liquid, adjuvant drug liquid and guide drug liquid which are kept stand for standby in the step (2) together, adding a proper amount of maltose, decocting with small fire, continuously stirring and uniformly stirring, and then closing the fire, discharging from a pot and filling into a medical medicine bottle.
Example 3:
the embodiment provides a medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid, which comprises, by weight, 550 parts of dark plum fruit, 450 parts of Chinese yam, 450 parts of hawthorn fruit, 450 parts of malt, 550 parts of Chinese date, 550 parts of poria cocos, 450 parts of coix seed, 450 parts of dwarf lilyturf tuber, 450 parts of dried orange peel, 450 parts of fragrant solomonseal rhizome, 650 parts of longan pulp, 450 parts of radish seed, 450 parts of sweet almond, 450 parts of sea buckthorn, 650 parts of bunge cherry seed, 550 parts of mulberry, 650 parts of fructus alpiniae oxyphyllae, 650 parts of lotus leaf, 550 parts of rhizoma polygonati and 650 parts of pagodatree flower bud.
The preparation method of the medicine-food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid comprises the following steps:
(1) Preparing a liquid medicine:
(1.1) preparation of monarch drug liquid: the monarch drug liquid medicine is prepared from dark plum, jujube, tuckahoe, mulberry and rhizoma polygonati in a monarch drug formula in the traditional Chinese medicine composition.
The preparation of the monarch drug liquid medicine specifically comprises the following steps:
(1.1.1) soaking: the dark plum, the jujube, the poria cocos, the mulberry and the rhizoma polygonati in the monarch drug formula in the traditional Chinese medicine composition are chopped and cleaned, then put into a decoction pot, and are added with 8500 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaked for 14 hours.
(1.1.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.1.3) combining the decocted liquid medicine, precipitating, and filtering with four layers of gauze for three times to further remove impurities in the liquid medicine.
(1.2) preparation of ministerial drug liquid: the ministerial drug liquid is taken by Chinese yam, dwarf lilyturf tuber, dried orange peel and bamboo in a ministerial drug formula in the traditional Chinese medicine composition.
The preparation of ministerial drug liquid comprises the following steps:
(1.2.1) soaking: cutting and cleaning rhizoma Dioscoreae, radix Ophiopogonis, pericarpium Citri Tangerinae and rhizoma Polygonati Odorati in the Chinese medicinal composition, placing into a decocting pot, adding 11000 parts of cold water according to the same weight parts as the Chinese medicinal composition, and soaking for 14 hr.
(1.2.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; and (3) performing third decoction according to the same method as the second decoction, and then filtering to take out the liquid medicine.
(1.2.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(1.3) preparation of adjuvant drug liquid: the adjuvant medicinal liquid is prepared from fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum and fructus Hippophae.
The preparation of the adjuvant medicine liquid specifically comprises the following steps:
(1.3.1) soaking: cutting fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum, and fructus Hippophae, cleaning, placing into a decocting pot, adding cold water 8500 parts, and soaking for 14 hr.
(1.3.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; and (3) performing third decoction according to the same method as the second decoction, and then filtering to take out the liquid medicine.
(1.3.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(1.4) preparation of a medicinal liquid: the Chinese medicinal liquid is prepared from arillus longan, semen Pruni, fructus Alpinae Oxyphyllae, folium Nelumbinis, and fructus Sophorae in the Chinese medicinal composition.
The preparation of the medicine liquid specifically comprises the following steps:
(1.4.1) soaking: the longan pulp, the bunge cherry seed, the fructus alpiniae oxyphyllae, the lotus leaf and the flos sophorae in the traditional Chinese medicine composition are chopped and cleaned, then put into a decoction pot, and added with 12000 parts of cold water according to the same weight parts as the traditional Chinese medicine composition, and soaked for 14 hours.
(1.4.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 2.5 hours, and filtering to obtain the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.4.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
(2) The monarch drug liquid medicine, ministerial drug liquid medicine, adjuvant drug liquid medicine and messenger drug liquid medicine prepared in the step (1) are placed in a shade place for standing for a period of time for standby. Standing for 5 to 8 days.
(3) Mixing the monarch drug liquid, ministerial drug liquid, adjuvant drug liquid and guide drug liquid which are kept stand for standby in the step (2) together, adding a proper amount of maltose, decocting with small fire, continuously stirring and uniformly stirring, and then closing the fire, discharging from a pot and filling into a medical medicine bottle.
The medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid is taken in the following way:
is suitable for children over 5 years old, and can be orally taken for 6 ml once and twice a day. Two months and one treatment course, twice a year. The conditioning is optimal in two seasons of the year, namely spring and winter.
The inventor provides clinical case statistics, including statistics of treatment effects of the medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae liquid of the invention on children with weak spleen and stomach, and statistics of treatment effects of the medicine of a control group on children with weak spleen and stomach, wherein the adopted medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae liquid is the medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae liquid in the embodiment 2.
The statistics are as follows:
1. data sources:
referring to the diagnosis standard of spleen and stomach weakness of children in the science of traditional Chinese medicine, 200 cases of children suffering from spleen and stomach weakness of chestnut's pediatrics are collected from 2021 month 1 to 2022 month 1, and 100 cases of treatment group and control group are respectively collected. Wherein, the treatment group has 53 men and 47 women; age 5-12 years, average age (8.36 years); the course of disease is 0.3-1.3 years old, and the average course of disease is 0.65 years old; severity of illness: severe 25, moderate 59, and mild 16. The control group has 48 men and 52 women; ages 5-12 years, with an average age of 8.22 years; the course of disease is 0.2-1.1 years old, and the average course of disease is 0.63 years old; severity of illness: severe 21, moderate 61, mild 18. The two groups of sex, age distribution, disease course and disease condition have no obvious statistical difference and have comparability.
2. The treatment method comprises the following steps:
the treatment group of children patients adopts the twenty-ingredient fructus alpiniae oxyphyllae liquid with homology of medicine and food according to the disease course and the disease severity of the children patients, and adopts different treatment courses, wherein the severe children patients with the disease course of more than 0.5 years take 5 treatment courses continuously; the severe infant with the disease course less than 0.5 years takes the medicine for 4 treatment courses continuously; the children with moderate disease course of more than 0.5 years take the medicine continuously for 4 treatment courses; the children with moderate disease course less than 0.5 years take the medicine for 3 treatment courses continuously; the mild infant with the disease course of more than 0.5 years takes 3 treatment courses continuously; the mild infant with the disease course less than 0.5 years takes 2 treatment courses continuously.
The control group of infants adopts the conventional spleen and stomach conditioning medicine, wherein spleen strengthening particles (national standard of medicine: Z43020453) are adopted for the infants with symptoms of abdominal distention, anorexia and loose stool, and the medication course is formulated according to the specification; infant spleen strengthening powder (national standard of medicine: Z42021570) is adopted for infants with dyspepsia, anorexia, abdominal distention and increased stool frequency, and a medication course is formulated according to the specification; for the children with constipation, milk food decrease, easy cold and dysplasia, WANGSHIBAOChi pill (national standard of medicine: Z32020646) is adopted, and the course of treatment is formulated according to the specification.
3. Standard of efficacy:
formulating an evaluation index of the curative effect of the spleen and stomach weakness of children by referring to the traditional Chinese medicine pediatric disease diagnosis curative effect standard in the traditional Chinese medicine disease diagnosis curative effect standard, wherein the curative effect is obvious: after the treatment course is finished, the symptoms related to the weakness of the spleen and the stomach disappear; the complexion is normal and the emotion is active; the appetite is good, the food intake is normal, the stool is normal, and the clinic cure can be judged. The method is effective: after the treatment course is finished, the symptoms related to the weakness of the spleen and the stomach are improved; the complexion is improved, and the mind is better; improving appetite, food intake, and stool. Invalidation: after the treatment course is finished, the symptoms related to spleen and stomach weakness are not obviously improved.
4. The statistics of the treatment and control groups are shown in table 1 below:
TABLE 1 statistical table of therapeutic effects in treatment and control groups
Group of Number of cases Clinical cure Effective and effective Invalidation of Total effective rate
Treatment group 100 57 41 2 98%
Control group 100 38 43 19 81%
As can be seen from table 1, the total effective rate of the treatment group is 98%, and the total effective rate of the control group is 81%. The treatment effect of the treatment group is better than that of the control group.
Analysis of statistical results by the inventors:
spleen-invigorating particles in the control group can be used for conditioning symptoms of weakness of spleen and stomach, abdominal distention, anorexia and loose stool, but have no way to condition repeated upper respiratory tract infection, and weakness of spleen and stomach often causes low immunity of infants, and insufficient resistance easily causes tonsil inflammation. The infant spleen-strengthening powder can be used for conditioning the symptoms of dyspepsia, milk and food deficiency, abdominal distension and increased stool frequency, but has no way to condition spleen and stomach and strengthen spleen and promote intelligence. The Wang's red-keeping pill can be used for conditioning infantile malnutrition, phlegm syncope convulsion, asthma and expectoration, milk food reduction, vomiting and diarrhea fever, constipation, four-time cold, weakness of spleen and stomach, dysplasia and other symptoms, and has curative effects on gastrointestinal disorder and phlegm food retardation, but has no way to achieve the two-item regulation of constipation and diarrhea.
The treatment group adopts the twenty-ingredient fructus alpiniae oxyphyllae liquid with homology of medicine and food, which is suitable for the children over 5 years old, and the raw material medicine selected by the formula fully considers the acceptance and the demand of the children over 5 years old on the effective medicine components and the influence of the side effect of the medicine on the children in the age period, so that the side effect on the children is reduced while the medicine effect is ensured.
The medicine and food homologous twenty-ingredient fructus alpiniae oxyphyllae liquid can be used for conditioning repeated constipation, diarrhea, dyspepsia, malabsorption and repeated upper respiratory tract infection caused by congenital spleen and stomach deficiency and acquired spleen and stomach weakness of children, and has good conditioning effect on sequelae (pharyngitis, tonsil hypertrophy, adenoid hypertrophy, allergic rhinitis and allergic tracheitis).
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. The medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid is characterized by being prepared by decocting a traditional Chinese medicine composition and maltose auxiliary materials, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 450 to 550 parts of dark plum fruit, 350 to 450 parts of Chinese yam, 350 to 450 parts of hawthorn fruit, 350 to 450 parts of malt, 450 to 550 parts of Chinese date, 450 to 550 parts of poria cocos, 350 to 450 parts of coix seed, 350 to 450 parts of dwarf lilyturf tuber, 350 to 450 parts of dried orange peel, 350 to 450 parts of fragrant solomonseal rhizome, 550 to 650 parts of longan pulp, 350 to 450 parts of radish seed, 350 to 450 parts of sweet almond, 350 to 450 parts of sea buckthorn, 550 to 650 parts of bunge cherry seed, 450 to 550 parts of mulberry fruit, 550 to 650 parts of fructus alpiniae oxyphyllae, 550 to 650 parts of lotus leaf, 450 to 550 parts of rhizoma polygonati and 550 to 650 parts of pagodatree flower bud.
2. The medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid of claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 500 parts of dark plum fruit, 400 parts of Chinese yam, 400 parts of hawthorn fruit, 400 parts of malt, 500 parts of Chinese date, 500 parts of poria cocos, 400 parts of coix seed, 400 parts of dwarf lilyturf tuber, 400 parts of dried orange peel, 400 parts of fragrant solomonseal rhizome, 600 parts of longan pulp, 400 parts of radish seed, 400 parts of sweet almond, 400 parts of sea buckthorn, 600 parts of bunge cherry seed, 500 parts of mulberry fruit, 600 parts of sharpleaf galangal fruit, 600 parts of lotus leaf, 500 parts of rhizoma polygonati and 600 parts of pagodatree flower bud.
3. The method for preparing the pharmaceutical and edible twenty-ingredient fructus alpiniae oxyphyllae liquid according to claim 1 or 2, which is characterized by comprising the following steps:
(1) Preparing a liquid medicine:
(1.1) preparation of monarch drug liquid: preparing monarch drug liquid medicine from dark plum, jujube, poria cocos, mulberry and rhizoma polygonati in a monarch drug formula in the traditional Chinese medicine composition;
(1.2) preparation of ministerial drug liquid: taking ministerial drug liquid from Chinese yam, dwarf lilyturf tuber, dried orange peel and rhizoma polygonati in a ministerial drug formula in the traditional Chinese medicine composition;
(1.3) preparation of adjuvant drug liquid: preparing adjuvant medicinal liquid from fructus crataegi, fructus Hordei Germinatus, coicis semen, raphani semen, semen Armeniacae amarum and fructus Hippophae;
(1.4) preparation of a medicinal liquid: the preparation method comprises preparing medicinal liquid from arillus longan, semen Pruni, fructus Alpinae Oxyphyllae, folium Nelumbinis and flos Sophorae Immaturus in the medicinal formula;
(2) The monarch drug liquid medicine, ministerial drug liquid medicine, adjuvant drug liquid medicine and messenger drug liquid medicine prepared in the step (1) are placed in a shade place for standing for a period of time for standby;
(3) Mixing the monarch drug liquid, ministerial drug liquid, adjuvant drug liquid and guide drug liquid which are kept stand for standby in the step (2) together, adding a proper amount of maltose, decocting with small fire, continuously stirring and uniformly stirring, and then closing the fire, discharging from a pot and filling into a medical medicine bottle.
4. The preparation method of the medicine-food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid of claim 3, which is characterized in that the preparation of the monarch medicine liquid specifically comprises the following steps:
(1.1.1) soaking: cutting dark plum, jujube, poria cocos, mulberry and rhizoma polygonati in a monarch drug formula in a traditional Chinese medicine composition, cleaning, putting into a decoction pot, adding 7500-8500 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.1.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.1.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
5. The preparation method of the medicine-food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid of claim 3, which is characterized in that the preparation of the ministerial medicine liquid specifically comprises:
(1.2.1) soaking: cutting and cleaning Chinese yam, dwarf lilyturf tuber, dried orange peel and fragrant solomonseal rhizome in a ministerial drug formula in the traditional Chinese medicine composition, putting the crushed and cleaned Chinese yam, dwarf lilyturf tuber, dried orange peel and fragrant solomonseal rhizome into a decoction pot, adding 9100-11000 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.2.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.2.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
6. The method for preparing the medicine-food homologous twenty-ingredient fructus alpiniae oxyphyllae sea buckthorn liquid according to claim 3, wherein the preparation of the adjuvant medicine liquid specifically comprises the following steps:
(1.3.1) soaking: cutting hawthorns, malt, coix seeds, radish seeds, sweet almonds and sea-buckthorn in an adjuvant prescription in the traditional Chinese medicine composition, cleaning, putting into a decoction pot, adding 7500-8500 parts of cold water according to the same weight parts as the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.3.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.3.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
7. The method for preparing the medicinal and edible twenty-ingredient fructus alpiniae oxyphyllae liquid of claim 3, wherein the preparing the medicinal liquid specifically comprises the following steps of:
(1.4.1) soaking: cutting longan pulp, bunge cherry seed, fructus alpiniae oxyphyllae, lotus leaf and pagodatree flower bud in a traditional Chinese medicine composition, cleaning, putting into a decoction pot, adding 11500-12500 parts of cold water according to the same parts by weight of the traditional Chinese medicine composition, and soaking for 10-14 hours;
(1.4.2) decocting for three times: boiling with strong fire and then with small fire for the first time after soaking, stirring in time during the boiling, removing foam floating on the surface to avoid overflow of the liquid medicine, decocting for 1.5-2.5 hours, and filtering to take out the liquid medicine; in the second decoction, adding cold water into the residue of the decoction pot, decocting again, adding water amount to submerge the residue, decocting according to the same method as in the first decoction, and filtering to obtain medicinal liquid; performing third decoction according to the same method as the second decoction, and filtering to obtain medicinal liquid;
(1.4.3) combining the decocted liquid medicine, precipitating, and filtering for multiple times by using gauze to further remove impurities in the liquid medicine.
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CN105327239A (en) * 2014-07-04 2016-02-17 浙江爱生药业有限公司 Traditional Chinese medicinal composition for treating children anorexia as well as preparation method and application of traditional Chinese medicinal composition
CN109646607A (en) * 2017-10-10 2019-04-19 葵花药业集团(佳木斯)有限公司 A kind of preparation method of children wheat jujube chewable tablets
CN110574918A (en) * 2019-09-26 2019-12-17 孟令涛 health food for tonifying spleen and consolidating constitution

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103141903A (en) * 2013-03-08 2013-06-12 马胜清 Pericarpium citri reticulatae hawthorn beverage
CN105327239A (en) * 2014-07-04 2016-02-17 浙江爱生药业有限公司 Traditional Chinese medicinal composition for treating children anorexia as well as preparation method and application of traditional Chinese medicinal composition
CN109646607A (en) * 2017-10-10 2019-04-19 葵花药业集团(佳木斯)有限公司 A kind of preparation method of children wheat jujube chewable tablets
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