CN114736253A - 一种通过酯化反应得到的酯类五乙酰京尼平苷衍生物及其制备方法、应用 - Google Patents
一种通过酯化反应得到的酯类五乙酰京尼平苷衍生物及其制备方法、应用 Download PDFInfo
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- CN114736253A CN114736253A CN202210384146.5A CN202210384146A CN114736253A CN 114736253 A CN114736253 A CN 114736253A CN 202210384146 A CN202210384146 A CN 202210384146A CN 114736253 A CN114736253 A CN 114736253A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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Abstract
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CN202210384146.5A CN114736253B (zh) | 2022-04-13 | 2022-04-13 | 一种通过酯化反应得到的酯类五乙酰京尼平苷衍生物及其制备方法、应用 |
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CN202210384146.5A CN114736253B (zh) | 2022-04-13 | 2022-04-13 | 一种通过酯化反应得到的酯类五乙酰京尼平苷衍生物及其制备方法、应用 |
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CN114736253A true CN114736253A (zh) | 2022-07-12 |
CN114736253B CN114736253B (zh) | 2023-05-26 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115785044A (zh) * | 2023-02-08 | 2023-03-14 | 山东省华泰营养健康产业技术研究院有限公司 | 一种具有降尿酸活性的亚氨基京尼平及其制备方法、应用 |
CN116173054A (zh) * | 2023-04-27 | 2023-05-30 | 中国中医科学院中药研究所 | 京尼平苷酸在制备降尿酸和/或治疗肾损伤药物中的应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102875617A (zh) * | 2012-09-12 | 2013-01-16 | 安徽医科大学 | 栀子苷衍生物及其制备方法及其在抗炎中的用途 |
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- 2022-04-13 CN CN202210384146.5A patent/CN114736253B/zh active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102875617A (zh) * | 2012-09-12 | 2013-01-16 | 安徽医科大学 | 栀子苷衍生物及其制备方法及其在抗炎中的用途 |
Non-Patent Citations (2)
Title |
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SHUWEN LEI ET AL: "Synthesis and biological evaluation of geniposide derivatives as potent and selective PTPlB inhibitors", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY * |
张红: "五乙酰栀子酰苯胺对D-GalN 所致小鼠急性肝损伤的保护作用", 安徽医科大学学报 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115785044A (zh) * | 2023-02-08 | 2023-03-14 | 山东省华泰营养健康产业技术研究院有限公司 | 一种具有降尿酸活性的亚氨基京尼平及其制备方法、应用 |
CN116173054A (zh) * | 2023-04-27 | 2023-05-30 | 中国中医科学院中药研究所 | 京尼平苷酸在制备降尿酸和/或治疗肾损伤药物中的应用 |
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