CN114272313A - External-use anti-inflammation sterilizing detumescence analgesic liquid - Google Patents
External-use anti-inflammation sterilizing detumescence analgesic liquid Download PDFInfo
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Abstract
The invention relates to the technical field of medicines, in particular to an external anti-inflammation, sterilization, detumescence and acesodyne liquid. An external anti-inflammatory, bactericidal, repercussive and analgesic liquid is characterized in that: the raw material group A comprises the following components in percentage by weight: 1-2 parts of monkshood, 1-2 parts of kusnezoff monkshood root, 3-5 parts of pubescent angelica root, 3-5 parts of shinyleaf pricklyash root, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 3-5 parts of divaricate saposhnikovia root, 1-2 parts of manchurian wildginger, 3-5 parts of clematis root, 3-5 parts of suberect spatholobus stem, 3-5 parts of pseudo-ginseng, 1-2 parts of arisaema consanguineum, 3-5 parts of drynaria rhizome, 3-5 parts of centipede, 3-5 parts of scorpion, 3-5 parts of spider, 3-5 parts of black ant, 3-5 parts of hornet and 3-5 parts of ground beetle; the raw material group B comprises the following components in percentage by weight: 3-5 parts of camphor, 3-5 parts of menthol, 3-5 parts of borneol, 3-5 parts of thymol, 3-5 parts of peppermint oil, 3-5 parts of clove oil and 10-20 parts of wintergreen oil; the invention has the beneficial effects that: the invention has the advantages of anti-inflammation, sterilization, detumescence and acesodyne.
Description
Technical Field
The invention relates to the technical field of medicines, in particular to an external anti-inflammation, sterilization, detumescence and acesodyne liquid.
Background
In the prior art, most of the medicines for treating bony spur, hyperosteogeny, scapulohumeral periarthritis, rheumatoid arthritis, lumbago, leg pain, edema of lower limbs and the like are oral preparations, and excessive taking of the medicines not only has influence on liver and kidney functions, but also has great irritation on stomach. Therefore, the external traditional Chinese medicine liquid has a large play space, but the preparation process of the medicinal liquor on the market at present is simple soaking, the processing and the preparation of the main medicine are simpler, the active ingredients of the medicine are lower, and the medicine effect of the traditional Chinese medicine is not further exerted.
Disclosure of Invention
In order to solve the technical problems, the invention provides an external anti-inflammatory, bactericidal, repercussive and analgesic liquid.
The technical scheme adopted by the invention is as follows:
the externally applied antiphlogistic, bactericidal, detumescence and analgesic liquid comprises a raw material group A and a raw material group B, and is characterized in that: the raw material group A is prepared from the following components in parts by weight: 1-2 parts of monkshood, 1-2 parts of kusnezoff monkshood root, 3-5 parts of pubescent angelica root, 3-5 parts of shinyleaf pricklyash root, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 3-5 parts of divaricate saposhnikovia root, 1-2 parts of manchurian wildginger, 3-5 parts of clematis root, 3-5 parts of suberect spatholobus stem, 3-5 parts of pseudo-ginseng, 1-2 parts of arisaema consanguineum, 3-5 parts of drynaria rhizome, 3-5 parts of centipede, 3-5 parts of scorpion, 3-5 parts of spider, 3-5 parts of black ant, 3-5 parts of hornet and 3-5 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 3-5 parts of camphor, 3-5 parts of menthol, 3-5 parts of borneol, 3-5 parts of thymol, 3-5 parts of peppermint oil, 3-5 parts of clove oil and 10-20 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix angelicae pubescentis slices by a dryer until 50% of water remains, and piling for 2-3 days until the radix angelicae pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.07-1.09 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
Preferably, the raw material group A is prepared from the following components in parts by weight: 1 part of monkshood, 1 part of kusnezoff monkshood root, 3 parts of pubescent angelica root, 3 parts of shinyleaf pricklyash root, 3 parts of garden balsam stem, 3 parts of safflower, 3 parts of divaricate saposhnikovia root, 1 part of manchurian wildginger, 3 parts of clematis root, 3 parts of suberect spatholobus stem, 3 parts of pseudo-ginseng, 1 part of arisaema tuber, 3 parts of drynaria rhizome, 3 parts of centipede, 3 parts of scorpion, 3 parts of spider, 3 parts of black ant, 3 parts of hornet and 3 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 3 parts of camphor, 3 parts of menthol, 3 parts of borneol, 3 parts of thymol, 3 parts of peppermint oil, 3 parts of clove oil and 10 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix Angelicae Pubescentis slices with a dryer until 50% water remains, and piling for 2 days until the radix Angelicae Pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.07 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
Preferably, the raw material group A is prepared from the following components in parts by weight: 2 parts of monkshood, 2 parts of kusnezoff monkshood root, 5 parts of pubescent angelica root, 5 parts of shinyleaf pricklyash root, 5 parts of garden balsam stem, 5 parts of safflower, 5 parts of divaricate saposhnikovia root, 2 parts of manchurian wildginger, 5 parts of clematis root, 5 parts of suberect spatholobus stem, 5 parts of pseudo-ginseng, 2 parts of arisaema tuber, 5 parts of drynaria rhizome, 5 parts of centipede, 5 parts of scorpion, 5 parts of spider, 5 parts of black ant, 5 parts of hornet and 5 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 5 parts of camphor, 5 parts of menthol, 5 parts of borneol, 5 parts of thymol, 5 parts of peppermint oil, 5 parts of clove oil and 20 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix Angelicae Pubescentis slices with a dryer until 50% water remains, and piling for 3 days until the radix Angelicae Pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.09 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
Preferably, the raw material group A is prepared from the following components in parts by weight: 2 parts of monkshood, 2 parts of kusnezoff monkshood root, 4 parts of pubescent angelica root, 4 parts of shinyleaf pricklyash root, 4 parts of garden balsam stem, 4 parts of safflower, 4 parts of divaricate saposhnikovia root, 2 parts of manchurian wildginger, 4 parts of clematis root, 4 parts of suberect spatholobus stem, 4 parts of pseudo-ginseng, 2 parts of arisaema tuber, 4 parts of drynaria rhizome, 4 parts of centipede, 4 parts of scorpion, 4 parts of spider, 4 parts of black ant, 4 parts of hornet and 4 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 4 parts of camphor, 4 parts of menthol, 4 parts of borneol, 4 parts of thymol, 4 parts of peppermint oil, 4 parts of clove oil and 15 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix angelicae pubescentis slices by a dryer until 50% of water remains, and piling for 2-3 days until the radix angelicae pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.08 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
The invention has the beneficial effects that: the Chinese herbal medicine liquid for regulating qi, relieving swelling and pain is relatively common, and has obviously improved curative effects of diminishing inflammation, sterilizing, relieving swelling and pain; ethanol with high concentration has strong disinfection effect. The radix angelicae pubescentis is more effectively treated by unique treatment on soreness and pain of waist and knees and the pretreatment of radix clematidis, so that the drug effect of dredging the channels and collaterals is increased, and the drug effect of promoting blood circulation and removing blood stasis is enhanced by the garden balsam stem. The invention has the advantages of diminishing inflammation, sterilizing, reducing swelling, relieving pain, promoting blood circulation, removing blood stasis, relaxing channels and activating collaterals and has good curative effect.
Detailed Description
In order to further explain the technical scheme of the invention, the invention is further explained as follows:
the processes of soaking, stirring, dissolving, filtering and the like used in the external anti-inflammatory, bactericidal, detumescence and acesodyne liquid are all carried out at normal temperature.
Pubescent angelica root, name of Chinese traditional medicine. Is dried root of Angelica gigas nakai of Umbelliferae. Collected in early spring when the seedlings just germinate or in late autumn when the stems and leaves wither, and distributed in Sichuan and Hubei of China. Radix Angelicae Pubescentis can be used for treating arthralgia due to wind-cold-dampness and soreness of waist and knees.
The root and stem of the clematis root are columnar, the length of the clematis root is 1.5-10 cm, and the diameter of the clematis root is 0.3-1.5 cm; the surface is light brown and yellow; residual stem base at the top end; the quality is tougher, and the section is fibrous; the lower side is provided with a plurality of thin roots. The root is in a slender cylindrical shape, slightly bent, 7-15 cm long and 0.1-0.3 cm in diameter; the surface is black brown, has fine longitudinal lines, has peel parts falling off, and exposes yellow white wood parts; the hard and brittle skin part is easy to break, the skin part of the fracture surface is wider, the wood part is light yellow and is slightly square, and cracks are often formed between the skin part and the wood part. Light smell, bland taste.
Garden balsam stem, also known as herb of variegated Qucao, Musca et Persica, etc. Perennial herbs like sunlight, afraid of dampness, heat-resistant and cold-resistant, are suitable for loose and fertile slightly-acid soil, but are also barren-resistant. Has strong adaptability, easy survival after transplantation and rapid growth. The stem, also known as garden balsam stem, can be used as a medicine and has the effects of promoting blood circulation to remove blood stasis, inducing diuresis to remove toxicity, and dredging channels and penetrating bones. The fresh grass can be pounded and externally applied for treating sore, furuncle, swelling and pain, and insect bite.
Example 1:
the raw material group A is prepared from the following components in parts by weight: 1-2 parts of monkshood, 1-2 parts of kusnezoff monkshood root, 3-5 parts of pubescent angelica root, 3-5 parts of shinyleaf pricklyash root, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 3-5 parts of divaricate saposhnikovia root, 1-2 parts of manchurian wildginger, 3-5 parts of clematis root, 3-5 parts of suberect spatholobus stem, 3-5 parts of pseudo-ginseng, 1-2 parts of arisaema consanguineum, 3-5 parts of drynaria rhizome, 3-5 parts of centipede, 3-5 parts of scorpion, 3-5 parts of spider, 3-5 parts of black ant, 3-5 parts of hornet and 3-5 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 3-5 parts of camphor, 3-5 parts of menthol, 3-5 parts of borneol, 3-5 parts of thymol, 3-5 parts of peppermint oil, 3-5 parts of clove oil and 10-20 parts of wintergreen oil;
aiming at the three medicinal materials in the traditional Chinese medicine, the invention has special pretreatment so as to exert greater efficacy.
The preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying slices of radix angelicae pubescentis with a dryer until 50% of water (basically in a semi-dry state) remains, wherein the drying temperature is 60-70 ℃ when the slices are dried with the dryer; piling for 2-3 days until the radix angelicae pubescentis becomes soft for later use (the property that the radix angelicae pubescentis becomes soft when being moistened is fully utilized);
secondary drying: soaking the slices of radix Angelicae Pubescentis after primary drying in saline water for 1 day, taking out, air drying (mainly for enhancing the medicinal effect of radix Angelicae Pubescentis, 1% -5% saline water can be used), adding radix Clematidis, parching to brown (equivalent to secondary drying, and parching to brown with a frying pan), and cooling; the two traditional Chinese medicines are fried to be yellow, so that the drug effect can be better exerted.
And (3) drying for the third time: adding the dried raw materials into the garden balsam stems with all the weight parts, stir-frying the garden balsam stems with wine to yellow (equivalent to three times of drying), pulverizing the garden balsam stems into powder, and sieving the powder with a sieve of 60 to 70 meshes for later use;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C; the traditional Chinese medicine materials are soaked in high-concentration ethanol, so that the efficacy of the traditional Chinese medicine materials is exerted, the traditional Chinese medicine materials are sterilized and prevented from rotting, and the quality guarantee period is greatly prolonged.
(3) Weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing the peppermint oil, the clove oil and the wintergreen oil, heating to 150-200 ℃, and heating the three kinds of oil for two purposes: 1. plays a role in killing bacteria in the oil (the shelf life is objectively prolonged); 2. evaporating water vapor in the oil (improving the purity of the oil objectively), then crushing camphor, menthol, borneol and thymol, putting into the hot oil for 5-10min (so as to fully heat and dissolve to exert the drug effect), finally mixing all the raw materials in the raw material group B uniformly, and cooling for later use to obtain a raw material D;
(4) and (2) adding the raw material group D in the step (3) into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.07-1.09 (the content of the medicine is increased), and storing in a bottle to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid.
Example 2: similar to the implementation of example 1, the present example changed the amount of the medicinal materials and the preparation time, and also achieved the same effect.
The raw material group A is prepared from the following components in parts by weight: the raw material group A is prepared from the following components in parts by weight: 1 part of monkshood, 1 part of kusnezoff monkshood root, 3 parts of pubescent angelica root, 3 parts of shinyleaf pricklyash root, 3 parts of garden balsam stem, 3 parts of safflower, 3 parts of divaricate saposhnikovia root, 1 part of manchurian wildginger, 3 parts of clematis root, 3 parts of suberect spatholobus stem, 3 parts of pseudo-ginseng, 1 part of arisaema tuber, 3 parts of drynaria rhizome, 3 parts of centipede, 3 parts of scorpion, 3 parts of spider, 3 parts of black ant, 3 parts of hornet and 3 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 3 parts of camphor, 3 parts of menthol, 3 parts of borneol, 3 parts of thymol, 3 parts of peppermint oil, 3 parts of clove oil and 10 parts of wintergreen oil;
aiming at the three medicinal materials in the traditional Chinese medicine, the invention has special pretreatment so as to exert greater efficacy.
The preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying slices of radix angelicae pubescentis with a dryer until 50% of water (basically in a semi-dry state) remains, wherein the drying temperature is 60-70 ℃ when the slices are dried with the dryer; stacking for 2 days until the radix Angelicae Pubescentis becomes soft for later use (fully utilizing the property that the radix Angelicae Pubescentis becomes soft when being wetted);
secondary drying: soaking the slices of radix Angelicae Pubescentis after primary drying in saline water for 1 day, taking out, air drying (mainly for enhancing the medicinal effect of radix Angelicae Pubescentis, 1% -5% saline water can be used), adding radix Clematidis, parching to brown (equivalent to secondary drying, and parching to brown with a frying pan), and cooling; the two traditional Chinese medicines are fried to be yellow, so that the drug effect can be better exerted.
And (3) drying for the third time: adding the dried raw materials into the garden balsam stems with all the weight parts, stir-frying the garden balsam stems with wine to yellow (equivalent to three times of drying), pulverizing the garden balsam stems into powder, and sieving the powder with a sieve of 60 to 70 meshes for later use;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C; the traditional Chinese medicine materials are soaked in high-concentration ethanol, so that the efficacy of the traditional Chinese medicine materials is exerted, the traditional Chinese medicine materials are sterilized and prevented from rotting, and the quality guarantee period is greatly prolonged.
(3) Weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing the peppermint oil, the clove oil and the wintergreen oil, heating to 150-200 ℃, and heating the three kinds of oil for two purposes: 1. plays a role in killing bacteria in the oil (the shelf life is objectively prolonged); 2. evaporating water vapor in the oil (improving the purity of the oil objectively), then crushing camphor, menthol, borneol and thymol, putting into the hot oil for 5-10min (so as to fully heat and dissolve to exert the drug effect), finally mixing all the raw materials in the raw material group B uniformly, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.07 (the content of the medicine is increased), and storing in a bottle to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid.
Example 3:
similar to the implementation of example 1, the present example changed the amount of the medicinal materials and the preparation time, and also achieved the same effect.
The raw material group A is prepared from the following components in parts by weight: 2 parts of monkshood, 2 parts of kusnezoff monkshood root, 5 parts of pubescent angelica root, 5 parts of shinyleaf pricklyash root, 5 parts of garden balsam stem, 5 parts of safflower, 5 parts of divaricate saposhnikovia root, 2 parts of manchurian wildginger, 5 parts of clematis root, 5 parts of suberect spatholobus stem, 5 parts of pseudo-ginseng, 2 parts of arisaema tuber, 5 parts of drynaria rhizome, 5 parts of centipede, 5 parts of scorpion, 5 parts of spider, 5 parts of black ant, 5 parts of hornet and 5 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 5 parts of camphor, 5 parts of menthol, 5 parts of borneol, 5 parts of thymol, 5 parts of peppermint oil, 5 parts of clove oil and 20 parts of wintergreen oil;
aiming at the three medicinal materials in the traditional Chinese medicine, the invention has special pretreatment so as to exert greater efficacy.
The preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying slices of radix angelicae pubescentis with a dryer until 50% of water (basically in a semi-dry state) remains, wherein the drying temperature is 60-70 ℃ when the slices are dried with the dryer; piling for 3 days until it becomes soft for later use (fully utilizing the property that radix Angelicae Pubescentis becomes soft when it is affected with damp);
secondary drying: soaking the slices of radix Angelicae Pubescentis after primary drying in saline water for 1 day, taking out, air drying (mainly for enhancing the medicinal effect of radix Angelicae Pubescentis, 1% -5% saline water can be used), adding radix Clematidis, parching to brown (equivalent to secondary drying, and parching to brown with a frying pan), and cooling; the two traditional Chinese medicines are fried to be yellow, so that the drug effect can be better exerted.
And (3) drying for the third time: adding the dried raw materials into the garden balsam stems with all the weight parts, stir-frying the garden balsam stems with wine to yellow (equivalent to three times of drying), pulverizing the garden balsam stems into powder, and sieving the powder with a sieve of 60 to 70 meshes for later use;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C; the traditional Chinese medicine materials are soaked in high-concentration ethanol, so that the efficacy of the traditional Chinese medicine materials is exerted, the traditional Chinese medicine materials are sterilized and prevented from rotting, and the quality guarantee period is greatly prolonged.
(3) Weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing the peppermint oil, the clove oil and the wintergreen oil, heating to 150-200 ℃, and heating the three kinds of oil for two purposes: 1. plays a role in killing bacteria in the oil (the shelf life is objectively prolonged); 2. evaporating water vapor in the oil (improving the purity of the oil objectively), then crushing camphor, menthol, borneol and thymol, putting into the hot oil for 5-10min (so as to fully heat and dissolve to exert the drug effect), finally mixing all the raw materials in the raw material group B uniformly, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.09 (the content of the medicine is increased), and storing in a bottle to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid.
Example 4:
similar to the implementation of example 1, the present example changed the amount of the medicinal materials and the preparation time, and also achieved the same effect.
The raw material group A is prepared from the following components in parts by weight: 2 parts of monkshood, 2 parts of kusnezoff monkshood root, 4 parts of pubescent angelica root, 4 parts of shinyleaf pricklyash root, 4 parts of garden balsam stem, 4 parts of safflower, 4 parts of divaricate saposhnikovia root, 2 parts of manchurian wildginger, 4 parts of clematis root, 4 parts of suberect spatholobus stem, 4 parts of pseudo-ginseng, 2 parts of arisaema tuber, 4 parts of drynaria rhizome, 4 parts of centipede, 4 parts of scorpion, 4 parts of spider, 4 parts of black ant, 4 parts of hornet and 4 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 4 parts of camphor, 4 parts of menthol, 4 parts of borneol, 4 parts of thymol, 4 parts of peppermint oil, 4 parts of clove oil and 15 parts of wintergreen oil;
aiming at the three medicinal materials in the traditional Chinese medicine, the invention has special pretreatment so as to exert greater efficacy.
The preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying slices of radix angelicae pubescentis with a dryer until 50% of water (basically in a semi-dry state) remains, wherein the drying temperature is 60-70 ℃ when the slices are dried with the dryer; stacking for 2 days until the radix Angelicae Pubescentis becomes soft for later use (fully utilizing the property that the radix Angelicae Pubescentis becomes soft when being wetted);
secondary drying: soaking the slices of radix Angelicae Pubescentis after primary drying in saline water for 1 day, taking out, air drying (mainly for enhancing the medicinal effect of radix Angelicae Pubescentis, 1% -5% saline water can be used), adding radix Clematidis, parching to brown (equivalent to secondary drying, and parching to brown with a frying pan), and cooling; the two traditional Chinese medicines are fried to be yellow, so that the drug effect can be better exerted.
And (3) drying for the third time: adding the dried raw materials into the garden balsam stems with all the weight parts, stir-frying the garden balsam stems with wine to yellow (equivalent to three times of drying), pulverizing the garden balsam stems into powder, and sieving the powder with a sieve of 60 to 70 meshes for later use;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C; the traditional Chinese medicine materials are soaked in high-concentration ethanol, so that the efficacy of the traditional Chinese medicine materials is exerted, the traditional Chinese medicine materials are sterilized and prevented from rotting, and the quality guarantee period is greatly prolonged.
(3) Weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing the peppermint oil, the clove oil and the wintergreen oil, heating to 150-200 ℃, and heating the three kinds of oil for two purposes: 1. plays a role in killing bacteria in the oil (the shelf life is objectively prolonged); 2. evaporating water vapor in the oil (improving the purity of the oil objectively), then crushing camphor, menthol, borneol and thymol, putting into the hot oil for 5-10min (so as to fully heat and dissolve to exert the drug effect), finally mixing all the raw materials in the raw material group B uniformly, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.08 (the content of the medicine is increased), and storing in a bottle to obtain the anti-inflammatory, bactericidal, repercussive and analgesic liquid.
Example 5: clinical application
At present, more than ten thousand patients suffering from the symptoms of bony spur, hyperosteogeny, scapulohumeral periarthritis, rheumatic arthritis, lumbocrural pain, edema of lower limbs and the like have been treated, and most of the patients have remarkable effects. To evaluate the effectiveness and safety of the product, 168 patients with bony spur, hyperosteogeny, scapulohumeral periarthritis, rheumatism and pain in waist and lower extremities were followed up, and the statistics of the treatment effect are shown in the following table.
The curative effect standard is as follows:
(1) and (3) healing: local pathological symptoms are eliminated, the function is recovered to be normal, and discomfort and rebound are avoided.
(2) The method has the following advantages: the local pathological symptoms are relieved or improved, partial basic recovery is realized, and discomfort or pathological symptoms also exist.
(3) And (4) invalidation: local pathological symptoms exist, are not relieved, and keep the original state.
In order to clearly understand the technical scheme and the technical effect of the invention, some typical cases will be described as follows:
typical case 1:
name: all certain;
symptoms are: femoral head necrosis, unable to squat down, walking pain is severe;
the treatment method comprises the following steps: the liquid for diminishing inflammation, sterilizing, diminishing swelling and relieving pain is applied to the affected part, and three courses of treatment (80 ml/bottle, five bottles one course of treatment) are carried out;
the effect is as follows: the pain is relieved after the liniment is applied for three days, the pain is not caused when people normally walk, the pain is completely cured after the liniment is used for three courses of treatment, and the condition of no rebound is not generated until now.
Typical case 2:
title: a certain dragon;
symptoms are: knee joint necrosis is not good for more than ten years in many provincial hospitals, the acupuncture, the medicine-taking and plaster-applying have no effect on various physical therapies of acupuncture, cupping and moxibustion, leg swelling and pain are very serious, the leg cannot be bent and moved, and the pain is severe from time to time;
the treatment method comprises the following steps: the external use is worn for thirty bottles;
the effect is as follows: the liniment takes effect for four days, is painless to walk, uses 11 bottles for two months, is completely non-swelling and non-pain, and then continues to use twenty bottles after radical treatment, and is stopped for about thirty bottles, so that the disease never recurs in the past three years, and the effect of radical treatment is achieved.
Typical case 3:
title: the room is born;
symptoms are: in the seventies, lumbar muscle strain is caused by long-term liking of mountain climbing sports, gonarthritis is very serious, walking pain is caused, and the effect is not achieved once the medicine is treated in various hospitals;
the treatment method comprises the following steps: the medicine is applied to the affected part, and the medicine is effective after being applied to one bottle, and six courses of treatment are carried out (80 ml/bottle, five bottles one course of treatment);
the effect is as follows: after the analgesic liquid is used for smearing one bottle, the pain is relieved, the patient can walk properly, and after the analgesic liquid is used for 3 months, the patient can walk normally, and six courses of treatment are carried out to achieve the effect of radical treatment.
Typical case 4:
title: a hu lady;
symptoms are: when the foot falls from four meters high, the foot is seriously injured by falling down, swollen and painful, and difficult to walk;
the treatment method comprises the following steps: the liquid has the effects of diminishing inflammation, sterilizing, relieving swelling and pain after being applied to an affected part for more than one month;
the effect is as follows: the liquid for diminishing inflammation, sterilizing, relieving swelling and pain is used for relieving swelling and pain after being smeared for four days, radical treatment is realized after one month of treatment course, and no rebound sign exists at present.
Having described preferred embodiments of the present invention, it will be appreciated by those skilled in the art that various changes, modifications and substitutions can be made in these embodiments without departing from the principles and spirit of the invention, and are within the scope of the invention.
Claims (4)
1. The externally applied antiphlogistic, bactericidal, detumescence and analgesic liquid comprises a raw material group A and a raw material group B, and is characterized in that: the raw material group A is prepared from the following components in parts by weight: 1-2 parts of monkshood, 1-2 parts of kusnezoff monkshood root, 3-5 parts of pubescent angelica root, 3-5 parts of shinyleaf pricklyash root, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 3-5 parts of divaricate saposhnikovia root, 1-2 parts of manchurian wildginger, 3-5 parts of clematis root, 3-5 parts of suberect spatholobus stem, 3-5 parts of pseudo-ginseng, 1-2 parts of arisaema consanguineum, 3-5 parts of drynaria rhizome, 3-5 parts of centipede, 3-5 parts of scorpion, 3-5 parts of spider, 3-5 parts of black ant, 3-5 parts of hornet and 3-5 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 3-5 parts of camphor, 3-5 parts of menthol, 3-5 parts of borneol, 3-5 parts of thymol, 3-5 parts of peppermint oil, 3-5 parts of clove oil and 10-20 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix angelicae pubescentis slices by a dryer until 50% of water remains, and piling for 2-3 days until the radix angelicae pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.07-1.09 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
2. The external anti-inflammatory, bactericidal, repercussive and analgesic liquid as claimed in claim 1, wherein: the raw material group A is prepared from the following components in parts by weight: 1 part of monkshood, 1 part of kusnezoff monkshood root, 3 parts of pubescent angelica root, 3 parts of shinyleaf pricklyash root, 3 parts of garden balsam stem, 3 parts of safflower, 3 parts of divaricate saposhnikovia root, 1 part of manchurian wildginger, 3 parts of clematis root, 3 parts of suberect spatholobus stem, 3 parts of pseudo-ginseng, 1 part of arisaema tuber, 3 parts of drynaria rhizome, 3 parts of centipede, 3 parts of scorpion, 3 parts of spider, 3 parts of black ant, 3 parts of hornet and 3 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 3 parts of camphor, 3 parts of menthol, 3 parts of borneol, 3 parts of thymol, 3 parts of peppermint oil, 3 parts of clove oil and 10 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix Angelicae Pubescentis slices with a dryer until 50% water remains, and piling for 2 days until the radix Angelicae Pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.07 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
3. The external anti-inflammatory, bactericidal, repercussive and analgesic liquid as claimed in claim 1, wherein: the raw material group A is prepared from the following components in parts by weight: 2 parts of monkshood, 2 parts of kusnezoff monkshood root, 5 parts of pubescent angelica root, 5 parts of shinyleaf pricklyash root, 5 parts of garden balsam stem, 5 parts of safflower, 5 parts of divaricate saposhnikovia root, 2 parts of manchurian wildginger, 5 parts of clematis root, 5 parts of suberect spatholobus stem, 5 parts of pseudo-ginseng, 2 parts of arisaema tuber, 5 parts of drynaria rhizome, 5 parts of centipede, 5 parts of scorpion, 5 parts of spider, 5 parts of black ant, 5 parts of hornet and 5 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 5 parts of camphor, 5 parts of menthol, 5 parts of borneol, 5 parts of thymol, 5 parts of peppermint oil, 5 parts of clove oil and 20 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix Angelicae Pubescentis slices with a dryer until 50% water remains, and piling for 3 days until the radix Angelicae Pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.09 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
4. The external anti-inflammatory, bactericidal, repercussive and analgesic liquid as claimed in claim 4, wherein: the raw material group A is prepared from the following components in parts by weight: 2 parts of monkshood, 2 parts of kusnezoff monkshood root, 4 parts of pubescent angelica root, 4 parts of shinyleaf pricklyash root, 4 parts of garden balsam stem, 4 parts of safflower, 4 parts of divaricate saposhnikovia root, 2 parts of manchurian wildginger, 4 parts of clematis root, 4 parts of suberect spatholobus stem, 4 parts of pseudo-ginseng, 2 parts of arisaema tuber, 4 parts of drynaria rhizome, 4 parts of centipede, 4 parts of scorpion, 4 parts of spider, 4 parts of black ant, 4 parts of hornet and 4 parts of ground beetle;
the raw material group B is prepared from the following components in parts by weight: 4 parts of camphor, 4 parts of menthol, 4 parts of borneol, 4 parts of thymol, 4 parts of peppermint oil, 4 parts of clove oil and 15 parts of wintergreen oil;
the preparation method of the external anti-inflammatory, bactericidal, detumescence and analgesic liquid comprises the following steps:
(1) removing fibrous roots and silt from all components of radix angelicae pubescentis, radix clematidis and garden balsam stems, slicing, and performing pretreatment according to the following steps:
primary drying: drying the whole amount of radix Angelicae Pubescentis slices with a dryer until 50% water remains, and piling for 2 days until the radix Angelicae Pubescentis slices are softened for later use;
secondary drying: soaking the radix Angelicae Pubescentis slices after primary drying in saline water for 1 day, taking out, air drying, adding radix Clematidis, parching to brown, and cooling;
and (3) drying for the third time: adding the dried raw materials into the whole amount of caulis et folium Gaultheriae Yunnanensis, parching with wine to brown, pulverizing, and sieving with 60-70 mesh sieve;
weighing and chopping the residual materials of the raw material group A in a specified amount, mixing all the raw materials in the raw material group A, and grinding the mixture to pass through a sieve with 90-100 meshes for later use;
(2) placing the raw materials obtained in the step (1) in the same container, adding 200 parts of 95% ethanol, sealing, soaking for 1 month, and filtering to obtain supernatant C;
(3) weighing all kinds of medicinal materials in a specified amount of the raw material group B, firstly mixing peppermint oil, clove oil and wintergreen oil, heating to 150-200 ℃, secondly crushing camphor, menthol, borneol and thymol, then putting into the hot oil for 5-10min, finally uniformly mixing all the raw materials in the raw material group B, and cooling for later use to obtain a raw material D;
(4) and (3) adding the raw material group D into the supernatant C in the step (1), stirring, filtering after the medicinal materials are completely dissolved, concentrating until the relative density is 1.08 to obtain the anti-inflammatory, bactericidal, swelling-subsiding and pain-relieving liquid, and storing in a bottle.
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