CN103623268B - Reconstruction pill for neurological rehabilitation and preparation method thereof - Google Patents
Reconstruction pill for neurological rehabilitation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a reconstruction pill for neurological rehabilitation and a preparation method thereof. The traditional Chinese medicine composition comprises sargentodoxa cuneata, semen vaccariae, roots of whiteflower hogfennel, laminaria japonica, semen litchi, semen raphani, akebia stem, lalang grass thizome, glabrous sarcandra herb and radix glycyrrhizae. The traditional Chinese medicine composition can be prepared into any clinically-acceptable oral pharmaceutical preparation according to the conventional traditional Chinese medicine preparation method. The traditional Chinese medicine composition made of the traditional Chinese medicines has the efficacy of dredging collaterals and recovering hemiplegia, dispelling wind and dredging collaterals, activating blood and eliminating stagnation, depressing qi and resolving phlegm, clearing heat and reducing blood pressure. Clinical curative effect observation verifies that the traditional Chinese medicine composition disclosed by the invention can be used for comprehensively treating apoplexy sequelae such as hemiplegia, facial paralysis, numbness of limbs and the like which are caused by apoplexy, and the curative effect is accurate, reliable and real. The traditional Chinese medicine composition is non-poisonous and harmless, safe and reliable, has no any side effect after being taken, and is safe in clinical use.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of apoplexy sequela and preparation method thereof, belong to the treatment by Chinese herbs field of apoplexy.
Background technology
Apoplexy is also apoplexy.Be divided into two types: in ischemic cerebral apoplexy and hemorrhagic apoplexy.Apoplexy is the general designation of Chinese medicine to acute cerebrovascular disease.It is suddenly fainted, syncope, the distortion of commissure that occurs together, dysphonia and occur that hemiplegia is a class disease of cardinal symptom.Because primary disease sickness rate is high, mortality rate is high, disability rate is high, relapse rate is high and complication is many, so medical circle is listed as one of three large diseases threatening human health its same coronary heart disease, cancer.
Hemiplegia is hemiplegia again, and refer to the dyskinesia of side upper and lower extremities, facial muscle and lingualis bottom, be a common sympton of acute cerebrovascular disease, hemiplegic patient can't take care of oneself mostly, has had a strong impact on the life quality of patient.
At present, the Chinese patent medicine being used for the treatment of apoplexy sequela also existing all is in various degree taken effect slow, the defect such as curative effect is remarkable not, haves much room for improvement.
Summary of the invention
Technical problem to be solved by this invention is slow, the defect such as curative effect is remarkable not that takes effect existing for Chinese patent medicine overcoming existing treatment apoplexy sequela, the Chinese medicine composition for the treatment of apoplexy sequela provide a kind of instant effect, determined curative effect, having no side effect;
Another technical problem to be solved by this invention is to provide a kind of method preparing above-mentioned Chinese medicine composition.
Above-mentioned technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for apoplexy sequela, comprise following component: Caulis Sargentodoxae, Herba Sarcandrae, Semen Vaccariae, Radix Peucedani, Thallus Laminariae (Thallus Eckloniae), Semen Litchi, Semen Raphani, Caulis Akebiae, Rhizoma Imperatae, Herba tradescantiae virginianae and Radix Glycyrrhizae.
Preferably, the weight portion of each component is: Caulis Sargentodoxae 8-20 part, Herba Sarcandrae 5-18 part, Semen Vaccariae 4-15 part, Radix Peucedani 4-15 part, Thallus Laminariae (Thallus Eckloniae) 4-15 part, Semen Litchi 2-7 part, Semen Raphani 2-7 part, Caulis Akebiae 2-7 part, Rhizoma Imperatae 2-6 part, Herba tradescantiae virginianae 1-6 part, Radix Glycyrrhizae 1-6 part.
Most preferred, the weight portion of each component is: Caulis Sargentodoxae 16 parts, Herba Sarcandrae 12 parts, Semen Vaccariae 9 parts, Radix Peucedani 8 parts, Thallus Laminariae (Thallus Eckloniae) 8 parts, Semen Litchi 6 parts, Semen Raphani 6 parts, Caulis Akebiae 5 parts, Rhizoma Imperatae 4 parts, Herba tradescantiae virginianae 2 parts, 2 parts, Radix Glycyrrhizae.
Caulis Sargentodoxae: be the dry rattan of plants of Lardizabalaceae Caulis Sargentodoxae.There is heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, effect of wind dispelling insecticide.Be applicable to stomachache, traumatic injury, dysmenorrhea, the diseases such as Fengshi Guanjie pain.
Semen Vaccariae: another name Wang Buliu, Vaccaria segetalis.For pinkwort Vaccaria segetalis Vaccariasegetalis(neck) dry seed of Garcker, there is promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, expedite the emergence of the function of stimulating milk secretion.Cure mainly menoxenia, agalactosis, difficult labour, the diseases such as carbuncle furunculosis.
Radix Peucedani: be the dry root of samphire RADIX PEUCEDANI Peucedanum dicursium (Miq.) Max-im. and Peucedanum praeruptorum DUNN P.praerupterum Dunn.Cold nature, bitter in the mouth, pungent.Return lung; Spleen; Liver Channel.Effect: dispelling wind and heat pathogens; Lowering the adverse-rising QI to resolve phlegm.
Thallus Laminariae (Thallus Eckloniae): be thallus or the Alariaceae plant Thallus Laminariae (Thallus Eckloniae) Ecklonia kurome Okam of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) Laminaria japonica Arsch..Cold in nature, salty in the mouth.Function cures mainly: hard masses softening and resolving, expectorant, diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema.
Semen Litchi: be the seed of sapindaceous plant Fructus Litchi Litchi chinensis Sonn..Nature and flavor are warm in nature, sweet in the mouth, micro-hardship.Function cures mainly promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.For colic of cold type stomachache, painful and swollen testis.
Semen Raphani: another name: Semen Raphani, reed Fu.Pleasant relieving constipation, help digestion de-swelling, lowering the adverse-rising QI to resolve phlegm, and have certain effect of weight reducing.For retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.
Caulis Akebiae: be the woody stems of dicotyledon plants of Lardizabalaceae Caulis Akebiae or threeleaf akebia, Caulis Akebiae (vanadium oxide xerogel).Belong to Lardizabalaceae Akebia.Nature and flavor are bitter, cool.Effect: pathogenic fire purging row water.Promoting blood circulation.
Rhizoma Imperatae: have another name called Rhizoma Imperatae, Rhizoma Imperatae, Rhizoma Imperatae is the rhizome of grass family Herba Imperatae.Sweet in the mouth, cold in nature; Effect: removing heat from blood benefit blood, heat clearing away blood pressure lowering.
Herba tradescantiae virginianae: be the herb of Commelianaceae plant spidewort, there is effect of promoting blood circulation and detumescence, powder detoxifcation.
Herba Sarcandrae: be the Herb of golden chestnut orchid Herba Pileae Scriptae Sarcandra glabra (Thunb.) Nakai, slightly warm in nature, bitter in the mouth, pungent.Function cures mainly: anti-inflammation, dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation.For pneumonia, appendicitis, cellulitis, rheumatic arthralgia, injury from falling down, tumor.
Chinese medicine composition of the present invention is based on the pathogenetic research of the deep layer of inventor to apoplexy and Therapeutic Principle thereof, simultaneously according to inventor's clinical experience and pharmaceutical research achievement for many years, filter out Tongluo Futan, dispelling wind and removing obstruction in the collateral, the crude drug of blood circulation promoting and dispersing pathogen accumulation, lowering the adverse-rising QI to resolve phlegm, heat clearing away blood pressure lowering, forms according to certain weight proportion prescription.
There is effect of better blood circulation promoting and blood stasis dispelling, dispelling pathogenic wind and eliminating phlegm: Folium Callicarpae Formosanae 3-9 part, Herba Polygoni Perfoliati 3-9 part, Radix Rubiae 2-7 part when adding the crude drug of following weight portion in the present invention in drug composition; Preferably, the weight portion of each raw material is: Folium Callicarpae Formosanae 8 parts, Herba Polygoni Perfoliati 8 parts, 5 parts, Radix Rubiae.
Folium Callicarpae Formosanae: be Herba Verbenae Callicarpa plant Folium Callicarpae Macrophyllae Callicarpa macrophylla Vahl, be used as medicine with root and leaf.Nature and flavor with return through: pungent, bitter, flat.Return liver, spleen, stomach warp; Function with cure mainly: dissipating blood stasis stops blooding, reducing swelling and alleviating pain.Leaf: for spitting blood, spitting of blood, epistaxis, has blood in stool.
Herba Polygoni Perfoliati: for Polygonaceae platymiscium passes through the herb of leaf knotweed.There is removing blood stasis and replenishing blood, effect of heat-clearing and toxic substances removing.
Radix Rubiae: this product is the dry root and rhizome of Maguireothamnus speciosus Radix Rubiae Rubia cordifolia L..Effect: cooling blood for hemostasis; Blood circulation promoting and blood stasis dispelling.
In side of the present invention, each medicine compatibility plays Tongluo Futan, dispelling wind and removing obstruction in the collateral together altogether, effect of blood circulation promoting and dispersing pathogen accumulation, lowering the adverse-rising QI to resolve phlegm, heat clearing away blood pressure lowering, and Chinese medicine composition of the present invention is treatment neuropathy, apoplexy, hemiplegia acute stage, the efficient good medicine of convalescent period and sequela.Observe through long term clinical results, the experimentation of the aspects such as pharmacology and biochemistry.Clinical proof this product has blood vessel dilating, improves microcirculation, increases blood flow, regulates function of nervous system, increases neurotrophy, promotes nerve metabolism, repairs the effects such as neurocyte function.For thromboangiitis obliterans, venous thrombosis, arteriosclerosis, cerebral thrombosis and hemorrhagic and ischemic sequelae (hemiplegia, hemiplegia, deviation of the mouth with numbness and paralysis, slobbering, slurred speech, stupor, swollen foot and knee, walks difficult, carpopedal spasm, coronary heart disease, amyotrophy, facial spasm, brain injury sequela, neuropathy, radiation disease is unable) etc. all there is significant clinical efficacy, treating both the principal and secondary aspects of a disease, clinical observation on the therapeutic effect confirms, Chinese medicine composition of the present invention is reliable for apoplectic hemiplegia determined curative effect, true.Chinese medicine composition of the present invention is nontoxic, safe and reliable, has no adverse reaction after taking, Clinical practice safety.
The present invention's each taste crude drug used can be bought at pharmacy and obtain.
Medicine activity component of the present invention can add various adjuvants required when preparing different dosage form, such as disintegrating agent, lubricant, adhesive etc., be prepared into the suitable clinical oral administration preparation of any one with the method for Chinese medicinal of routine, described oral formulations can be pill, powder, granule, capsule, tablet, oral liquid, drop pill etc.
A kind of preparation method of Chinese medicine composition of the present invention: after being taken by described weight by each crude drug of the present invention, pulverize, sieve (can be such as 80-300 mesh sieve), to obtain final product.Certainly, after also each crude drug can being pulverized, add the adjuvant needed for preparations shaping or excipient, be conventionally prepared into capsule, tablet or pill.
The another kind of preparation method of Chinese medicine composition of the present invention: take each crude drug by described weight portion; By each crude drug soak by water, merge decoction liquor, filter, filtrate is condensed into clear paste, and add adjuvant or the excipient of preparations shaping, preparations shaping, to obtain final product.
The usage of Chinese medicine composition of the present invention and consumption: dosage of the present invention depends on the factor such as age, health status of concrete dosage form, patient.As guidance: usage and dosage: capsule, each capsule is containing 0.3 gram of crude drug, and oral 3 to 4 at every turn, 3 times on the one 15 days is a course for the treatment of.
Detailed description of the invention
The present invention is further described below in conjunction with specific embodiment; these embodiments are only exemplary; what those skilled in the art should understand that is; can modify to the details of technical solution of the present invention and form lower without departing from the spirit and scope of the present invention or replace, but these amendments and replacement all fall within the scope of protection of the present invention.
The preparation of embodiment 1 capsule
Each crude drug (unit: g): Caulis Sargentodoxae 8, Herba Sarcandrae 5, Semen Vaccariae 4, Radix Peucedani 4, Thallus Laminariae (Thallus Eckloniae) 4, Semen Litchi 2, Semen Raphani 2, Caulis Akebiae 2, Rhizoma Imperatae 2, Herba tradescantiae virginianae 1, Radix Glycyrrhizae 1 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 4 times of weight for the first time, decocts 2 hours, and add water 5 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 2 capsule
Each crude drug (unit: g): Caulis Sargentodoxae 20, Herba Sarcandrae 18, Semen Vaccariae 15, Radix Peucedani 15, Thallus Laminariae (Thallus Eckloniae) 15, Semen Litchi 7, Semen Raphani 7, Caulis Akebiae 7, Rhizoma Imperatae 6, Herba tradescantiae virginianae 6, Radix Glycyrrhizae 6 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 3 capsule
Each crude drug (unit: g): Caulis Sargentodoxae 16, Herba Sarcandrae 12, Semen Vaccariae 9, Radix Peucedani 8, Thallus Laminariae (Thallus Eckloniae) 8, Semen Litchi 6, Semen Raphani 6, Caulis Akebiae 5, Rhizoma Imperatae 4, Herba tradescantiae virginianae 2, Radix Glycyrrhizae 2 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 4 times of weight for the first time, decocts 2 hours, and add water 5 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.30-1.35(55 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 4 capsule
Each crude drug (unit: g): Caulis Sargentodoxae 8, Herba Sarcandrae 5, Semen Vaccariae 4, Radix Peucedani 4, Thallus Laminariae (Thallus Eckloniae) 4, Semen Litchi 2, Semen Raphani 2, Caulis Akebiae 2, Rhizoma Imperatae 2, Herba tradescantiae virginianae 1, Radix Glycyrrhizae 1, Folium Callicarpae Formosanae 3, Herba Polygoni Perfoliati 3, Radix Rubiae 2 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 4 times of weight for the first time, decocts 2 hours, and add water 5 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.30-1.35(55 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 5 capsule
Each crude drug (unit: g): Caulis Sargentodoxae 20, Herba Sarcandrae 18, Semen Vaccariae 15, Radix Peucedani 15, Thallus Laminariae (Thallus Eckloniae) 15, Semen Litchi 7, Semen Raphani 7, Caulis Akebiae 7, Rhizoma Imperatae 6, Herba tradescantiae virginianae 6, Radix Glycyrrhizae 6, Folium Callicarpae Formosanae 9, Herba Polygoni Perfoliati 9, Radix Rubiae 7 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 6 capsule
Each crude drug (unit: g): Caulis Sargentodoxae 16, Herba Sarcandrae 12, Semen Vaccariae 9, Radix Peucedani 8, Thallus Laminariae (Thallus Eckloniae) 8, Semen Litchi 6, Semen Raphani 6, Caulis Akebiae 5, Rhizoma Imperatae 4, Herba tradescantiae virginianae 2, Radix Glycyrrhizae 2, Folium Callicarpae Formosanae 8, Herba Polygoni Perfoliati 8, Radix Rubiae 5 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, add appropriate amount of starch, mixing, dry, pulverize, add appropriate amount of ethanol and make granule, dry, granulate, filled capsules, to obtain final product.
The preparation of embodiment 7 watered pill
Each crude drug (unit: g): Caulis Sargentodoxae 16, Herba Sarcandrae 12, Semen Vaccariae 9, Radix Peucedani 8, Thallus Laminariae (Thallus Eckloniae) 8, Semen Litchi 6, Semen Raphani 6, Caulis Akebiae 5, Rhizoma Imperatae 4, Herba tradescantiae virginianae 2, Radix Glycyrrhizae 2 is taken by following weight;
Above-mentioned each crude drug is decocted with water secondary, and add water 6 times of weight for the first time, decocts 2 hours, and add water 4 times of weight for the second time, decocts 1.5 hours; By decoction liquor merge, filter, it is 1.17-1.19(60 DEG C that filtrate is concentrated into relative density) clear paste; Merge twice clear paste, make binding agent with water, generally make the watered pill, dry, subpackage, packaging, gets product.
The preparation of embodiment 8 water-honeyed pill
Each crude drug (unit: g): Caulis Sargentodoxae 16, Herba Sarcandrae 12, Semen Vaccariae 9, Radix Peucedani 8, Thallus Laminariae (Thallus Eckloniae) 8, Semen Litchi 6, Semen Raphani 6, Caulis Akebiae 5, Rhizoma Imperatae 4, Herba tradescantiae virginianae 2, Radix Glycyrrhizae 2 is taken by following weight;
Mixed by each crude drug and be ground into fine powder, cross 100 mesh sieves, get appropriate refined honey, make binding agent with refined honey, water, generally make water-honeyed pill, dry, subpackage, packaging, gets product.
The clinical observation on the therapeutic effect test of test example 1 traditional Chinese medicine composition for treating apoplexy sequela of the present invention
One, physical data: the 152 routine patients that outpatient service is accepted for medical treatment all meet the clinical criteria of apoplexy sequela, all there is the symptoms such as hemiplegia, facial hemiparalysis, numb limbs and tense tendons, language function obstacle; 152 routine patients are divided into 2 groups at random, often organize 76 examples; 2 groups of no significant differences on sex, age, the course of disease and coincident with severity degree of condition.
Two, trial drug
Medicine prepared by embodiment of the present invention 1-8.
Three, Therapeutic Method
152 patients are divided into 2 groups respectively at random, that is: test 1 group and test 2, often organize each 76 example, test 1 group adopt prepared by embodiment 1-3 capsule treatment, test 2 groups adopt prepared by embodiment 4-6 capsule treatment; Oral, one time 4 (0.3g crude drug/grain), 3 times on the one 15 days is a course for the treatment of, treats 3 courses for the treatment of altogether.
Four, efficacy assessment standard
Effective: clinical symptoms disappears substantially, language function recovers normal, and patient can walk, and life can take care of oneself;
Effective: clinical symptoms takes a turn for the better to some extent, language function is normal, and crutch can be leaned on to walk, and life is taken care of oneself substantially;
Invalid: symptom is without any improvement.
Five, clinical observation result
Clinical observation result is in table 1.
The clinical observation on the therapeutic effect result of the test of table 1 traditional Chinese medicine composition for treating apoplexy sequela of the present invention
Clinical observation on the therapeutic effect result shows, Chinese medicine composition of the present invention in the sequela such as wind-induced hemiplegia, facial hemiparalysis, numb limbs and tense tendons, language function obstacle there is significant curative effect; Wherein, the therapeutic effect testing 2 groups significantly will be better than the therapeutic effect of test 1 group; Safety observations find, do not observe any clinical adverse, show Chinese medicine composition clinical practice of the present invention safely, have no side effect.
Claims (7)
1. treat the Chinese medicine composition of apoplexy sequela for one kind, it is characterized in that, be made up of each crude drug of following weight portion: Caulis Sargentodoxae 8-20 part, Herba Sarcandrae 5-18 part, Semen Vaccariae 4-15 part, Radix Peucedani 4-15 part, Thallus Laminariae (Thallus Eckloniae) 4-15 part, Semen Litchi 2-7 part, Semen Raphani 2-7 part, Caulis Akebiae 2-7 part, Rhizoma Imperatae 2-6 part, Herba tradescantiae virginianae 1-6 part and Radix Glycyrrhizae 1-6 part.
2. according to Chinese medicine composition according to claim 1, it is characterized in that, the weight portion of each crude drug is: Caulis Sargentodoxae 16 parts, Herba Sarcandrae 12 parts, Semen Vaccariae 9 parts, Radix Peucedani 8 parts, Thallus Laminariae (Thallus Eckloniae) 8 parts, Semen Litchi 6 parts, Semen Raphani 6 parts, Caulis Akebiae 5 parts, Rhizoma Imperatae 4 parts, Herba tradescantiae virginianae 2 parts, 2 parts, Radix Glycyrrhizae.
3. treat the Chinese medicine composition of apoplexy sequela for one kind, it is characterized in that, be made up of each crude drug of following weight portion: Caulis Sargentodoxae 8-20 part, Herba Sarcandrae 5-18 part, Semen Vaccariae 4-15 part, Radix Peucedani 4-15 part, Thallus Laminariae (Thallus Eckloniae) 4-15 part, Semen Litchi 2-7 part, Semen Raphani 2-7 part, Caulis Akebiae 2-7 part, Rhizoma Imperatae 2-6 part, Herba tradescantiae virginianae 1-6 part, Radix Glycyrrhizae 1-6 part, Folium Callicarpae Formosanae 3-9 part, Herba Polygoni Perfoliati 3-9 part and Radix Rubiae 2-7 part.
4. according to Chinese medicine composition according to claim 3, it is characterized in that, the weight portion of each crude drug is: Caulis Sargentodoxae 16 parts, Herba Sarcandrae 12 parts, Semen Vaccariae 9 parts, Radix Peucedani 8 parts, Thallus Laminariae (Thallus Eckloniae) 8 parts, Semen Litchi 6 parts, Semen Raphani 6 parts, Caulis Akebiae 5 parts, Rhizoma Imperatae 4 parts, Herba tradescantiae virginianae 2 parts, 2 parts, Radix Glycyrrhizae, Folium Callicarpae Formosanae 8 parts, Herba Polygoni Perfoliati 8 parts, 5 parts, Radix Rubiae.
5. prepare a method for claim 1-4 Chinese medicine composition described in any one, comprise the following steps:
(1), each crude drug is taken by described weight proportion;
(2), by each crude drug soak by water, merge decoction liquor, filter, filtrate is condensed into clear paste, adds the adjuvant of preparations shaping, preparations shaping, to obtain final product.
6. prepare a method for claim 1-4 Chinese medicine composition described in any one, comprise the following steps: each crude drug is pulverized, sieves, add the adjuvant needed for preparations shaping, be conventionally prepared into capsule, tablet or pill.
7. the purposes of claim 1-4 Chinese medicine composition described in any one in preparation treatment apoplexy sequela medicine.
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| CN1224614C (en) * | 2000-04-03 | 2005-10-26 | 赛诺菲-安万特 | Indolin-2-one derivatives, preparation and their use as ocytocin receptor ligands |
| CN101537091A (en) * | 2008-03-19 | 2009-09-23 | 北京汉潮联创中药科技有限公司 | Chinese medicinal preparation for treating stroke |
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