CN114272173A - Rose wash-free antibacterial skin-care foam type hand sanitizer and preparation method and application thereof - Google Patents
Rose wash-free antibacterial skin-care foam type hand sanitizer and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to a rose washing-free bacteriostatic skin-care foam type hand sanitizer and a preparation method and application thereof. The hand sanitizer comprises the following components: rose extract, polyhydric alcohol, foaming agent, auxiliary bactericide, pH regulator and water. The invention also provides a method for preparing the hand sanitizer and the application of the hand sanitizer to the no-clean disinfection of corresponding microorganisms. The hand sanitizer disclosed by the invention is not added with alcohol, utilizes the skin care, bacteriostasis, fragrance and other effects of the rose extract and is supplemented with a guanidine polymer antibacterial agent, so that the hand sanitizer is green and environment-friendly and has an obvious bacteriostasis effect; adding flos Rosae Rugosae extract, fructus Rosae Normalis extract, grape seed oil, glycerol, 1, 2-propylene glycol, sorbitol, vitamin E, etc., and has effects of whitening skin, keeping moisture and caring skin; the generated foam is white and fine, can be quickly dissipated after being used, and is free from washing hands; essence is not required to be added, and mild rose fragrance can be given off; the preparation method is simple and can obtain the hand sanitizer by only uniformly mixing.
Description
Technical Field
The invention relates to the technical field of daily chemical articles, and relates to a rose wash-free antibacterial skin-care foam type hand sanitizer and a preparation method and application thereof.
Background
At present, public health services are receiving high attention worldwide. In the prevention and control of diseases caused by the spread of microorganisms such as viruses, hand washing is a very important measure, and thus hand washing solutions become an indispensable and extremely important daily product for preventing the spread of viruses in daily life.
Alcohol is an indispensable sterilization component of most hand washing solutions on the market at present, but has irritation to human skin. As an alternative component of alcohol, some hand sanitizer uses antibacterial agents such as o-phenylphenol, p-chloroxylenol, chlorhexidine and the like as single antibacterial components, but the antibacterial agents have no skin care effect, are high in irritation, have certain carcinogenicity and have irritating peculiar smell.
Compared with the traditional liquid type or gel type hand sanitizer, the foam type hand sanitizer has the advantages of small dosage, no silk adhesion, convenient use and more comfortable experience. However, the existing foam type hand sanitizer usually needs to be washed with water after use, so that the time and the occasion for washing hands are limited, and the hand sanitizer is inconvenient to carry during traveling and the like.
At present, the hand sanitizer without hand washing has a good application prospect, but the foaming effect of conventional bactericides such as alcohol is poor, the skin is irritated, other bactericides often have peculiar smell or pungent smell, other people can be affected when the hand sanitizer is used in public places, the sterilization effect needs to be improved, and certain carcinogenicity and environmental pollution exist. Therefore, it is highly desirable to develop a leave-in, bacteriostatic, safe, non-toxic, skin care, foam-type hand sanitizer, and it is expected that such a hand sanitizer will have great application value.
Disclosure of Invention
In view of the problems in the prior art, the invention provides a rose wash-free antibacterial skin-care foam type hand sanitizer in a first aspect, wherein the hand sanitizer comprises the following components: rose extract, polyhydric alcohol, foaming agent, bactericide, pH regulator and water.
In a second aspect, the present invention provides a method of preparing a foamed hand sanitizer according to the first aspect of the present invention, the method comprising the steps of:
(1) measuring various components of the hand sanitizer;
(2) adding water into a container at normal temperature, adding the components into the water, and uniformly mixing;
(3) standing for 0.2-1.5h to obtain the hand sanitizer.
In a third aspect, the invention provides use of a hand cleanser according to the first aspect of the invention or a hand cleanser prepared by the method of the second aspect of the invention for the leave-on disinfection of a corresponding microorganism.
Compared with the prior art, the invention has the following technical advantages and characteristics:
(1) the foam hand sanitizer has the characteristic of hand washing free, is extremely quick to dry, and can be dried by rubbing hands for 10 seconds.
(2) The hand sanitizer disclosed by the invention does not use irritant chemical bactericides such as alcohol and the like, adds a novel environment-friendly guanidine disinfectant polyhexamethylene guanidine hydrochloride as an auxiliary bactericide, has extremely strong sterilization and bacteriostasis performances, is broad-spectrum and efficient, has no toxic or side effect, is free from corrosivity and irritation, is safe to use, is degradable in a natural environment, and is environment-friendly and pollution-free.
(3) The rose extract in the hand sanitizer is rich in citronellol, phenethyl alcohol and other active substances with natural bacteriostatic and bactericidal effects, can inhibit microorganisms carried by parts such as hands, and is mild and does not hurt the hands. In addition, the rose extract, the roxburgh rose extract, the grape seed oil, the vitamin E and the like have the effects of resisting oxidation, resisting aging and the like, and have a good skin care effect on hand skin.
(4) The hand sanitizer contains glycerol, sorbitol, 1, 2-propylene glycol and other polyols, and has the effects of moisturizing and moistening the skin.
(5) The hand sanitizer disclosed by the invention is not added with essence, but the rose extract is used for replacing the essence, so that the hand sanitizer has natural rose fragrance and is pleasant.
(6) In the aspect of preparation process, the components are uniformly mixed at normal temperature (for example, the components can be uniformly mixed by adopting a homogenizer for 2-5 min), and the mixture is placed for 0.2-1.5h and then filled into a foaming bottle for use. Compared with other hand sanitizer which needs long-time standing and aging and is complex to operate, the hand sanitizer is simpler and faster to prepare and is convenient to produce.
Drawings
Figure 1 shows the pumped foam morphology and stability of the hand sanitizers prepared in examples 1-8.
FIG. 2 shows the bacteriostatic effect (zone diameter) of the hand sanitizers prepared in examples 1-8 on E.coli.
FIG. 3 shows the bacteriostatic effect (zone diameter) of the hand sanitizers prepared in examples 1-8 on Staphylococcus aureus.
FIG. 4 shows the bacteriostatic effects of the optimized hand sanitizer prepared in example 9 on Escherichia coli (upper panel) and Staphylococcus aureus (lower panel).
FIG. 5 shows the comparative effect (zone of inhibition) of the hand sanitizer prepared in example 9 on inhibition of Escherichia coli, wherein A is the hand sanitizer prepared in example 9 (zone of inhibition diameter 21mm), B is the Hualu brand hand sanitizer prepared in Hualu brand (zone of inhibition diameter 19mm), C is the Kangdali hand sanitizer prepared in Kangdali (zone of inhibition diameter 14mm), D is the Dialu brand hand sanitizer prepared in Dalu brand (zone of inhibition diameter 15mm), and E is the negative control prepared in Dalu brand (zone of inhibition diameter 14 mm).
Fig. 6 shows a process flow diagram for preparing a hand sanitizer of the present invention.
Fig. 7 shows the finished hand sanitizer of the present invention and its use.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
As described above, the invention provides a rose wash-free bacteriostatic skin-care foam type hand sanitizer in a first aspect, wherein the hand sanitizer comprises the following components: rose extract, polyhydric alcohol, foaming agent, auxiliary bactericide, pH regulator and water.
In some preferred embodiments, the rose extract is rose hydrosol and/or rose essential oil, more preferably rose hydrosol.
In other preferred embodiments, the polyol is at least one selected from the group consisting of glycerol, 1, 2-propanediol, and sorbitol. More preferably, the polyol comprises at least glycerol. It is further preferred that the polyhydric alcohol not only includes glycerin, but also includes at least one of 1, 2-propanediol and sorbitol. It is still further preferred that the polyol further comprises 1, 2-propanediol and sorbitol in addition to glycerin.
In other preferred embodiments, the foaming agent is dodecyl dimethyl betaine.
In other preferred embodiments, the co-biocide is polyhexamethyleneguanidine hydrochloride.
In other preferred embodiments, the pH adjusting agent is triethanolamine.
In other preferred embodiments, the hand sanitizer further comprises: rosa roxburghii extract, grape seed oil, vitamin E, 1, 2-propylene glycol, and/or sorbitol.
In other preferred embodiments, the hand sanitizer comprises, in volume percent of the hand sanitizer:
16-35% rose extract, for example 20, 25 or 30%;
0.1-1.5% of glycerol, for example 0.2, 0.5, 1.0%;
blowing agents 0.5-4%, for example 1,2 or 3%;
0.25-0.5% of auxiliary bactericide, for example 0.3, 0.35, 0.4 or 0.45%;
pH regulator 0.01-0.1%, such as 0.05%;
0-0.5%, such as 0.1, 0.2, 0.3 or 0.4% of Rosa roxburghii Tratt extract;
0-0.5%, for example 0.1, 0.2, 0.3 or 0.4% of grape seed oil;
vitamin E0-0.5%, for example 0.1, 0.2, 0.3 or 0.4%;
0-1% of 1, 2-propanediol, for example 0.1, 0.2, 0.3 or 0.4, 0.5, 0.6, 0.7, 0.8 or 0.9%; and
sorbitol 0-1%, for example 0.1, 0.2, 0.3 or 0.4, 0.5, 0.6, 0.7, 0.8 or 0.9%.
In other preferred embodiments, the composition of the hand sanitizer is as follows, in volume percent of the hand sanitizer: 16-35% of rose extract, 0.1-1.5% of glycerol, 0.5-4% of foaming agent, 0.25-0.5% of bactericide, 0.01-0.1% of pH regulator, 0.1-0.5% of roxburgh rose extract, 0.05-0.5% of grape seed oil, 0.01-0.5% of vitamin E, 0.1-1% of 1, 2-propylene glycol, 0.1-1% of sorbitol and the balance of water (such as deionized water or distilled water).
The rose extract is generally used as a raw material of a daily skin care product, but other effects such as the efficacy of the rose extract as a bacteriostatic agent are not sufficiently exploited. The present inventors have found that rose extract in fact has excellent qualities which are particularly suitable as a component of leave-on hand sanitizers. For example, the rose extract is rich in natural active antibacterial substances such as citronellol and phenethyl alcohol, and has a remarkable antibacterial effect. The rose extract has a very pleasant smell, can overcome the disadvantage of the irritating taste commonly found in the existing bactericides, and also has a skin-care effect.
The invention provides a hand sanitizer taking a rose extract as a main antibacterial component, and the hand sanitizer is supplemented with a roxburgh rose extract and grape seed oil, so that a sufficient skin care effect can be achieved. In addition, in the hand sanitizer of the present invention, not only the rose extract itself but also, for example, dodecyl dimethyl betaine, which is used as a foaming agent, have bacteriostatic effects, and these components, in combination with an auxiliary bactericide such as polyhexamethylene guanidine hydrochloride and the like, can achieve very excellent bacteriostatic and bactericidal effects. In addition, the hand sanitizer also comprises glycerin, sorbitol, 1, 2-propylene glycol and vitamin E, and the components are added, so that the hand sanitizer has good moisturizing, moistening, antioxidant and other effects.
In short, the rose no-clean antibacterial skin-care foam type hand sanitizer disclosed by the invention is fine and stable in foam, is volatile after being kneaded, is not required to be washed by water, is convenient to use, has the antibacterial and skin-care effects, is mild and does not hurt hands, and has the advantages of natural rose fragrance and the like.
In a second aspect, the present invention provides a method of preparing a foamed hand sanitizer according to the first aspect of the present invention, the method comprising the steps of:
(1) measuring various components of the hand sanitizer;
(2) adding water into a container at normal temperature, adding the components into water, and uniformly mixing, for example, homogenizing for 2-5min by a homogenizer;
(3) standing for 0.2h to 1.5h to obtain the hand sanitizer.
Preferably, the hand sanitizer can be bottled for use in a bubble bottle.
The preparation method of the hand sanitizer is very simple and rapid, is particularly suitable for mass production, has low production cost, and has huge economic value and application prospect.
In some preferred embodiments, the ratios of the components used in the process of the invention are as follows: 16-35% of rose extract, 0.34% of glycerol, 0.5-4% of dodecyl dimethyl betaine, 0.25-0.5% of polyhexamethylene guanidine hydrochloride, 0.02% of triethanolamine, 0.2% of rosa roxburghii tratt extract, 0.1% of grape seed oil, 0.02% of vitamin E, 0.1% of 1, 2-propylene glycol, 0.34% of sorbitol and the balance of water (such as distilled water or deionized water).
In a third aspect, the invention provides use of a hand cleanser according to the first aspect of the invention or a hand cleanser prepared by the method of the second aspect of the invention for the leave-on disinfection of a corresponding microorganism.
Examples
The present invention will be illustrated below by way of examples, but the scope of protection of the present invention is not limited to these examples.
Example 1
The amount of the hand sanitizer prepared in this example was 100mL, and the specific composition is shown in table 1 below.
TABLE 1 materials and amounts used for preparing the hand sanitizer of example 1
| Name of raw materials | Volume (mL) | Volume percent |
| Rose extract (Rose pure dew) | 16 | 16 |
| Polyhexamethylene guanidine hydrochloride | 0.25 | 0.25 |
| |
2 | 2％ |
| Rosa roxburghii extract | 0.2 | 0.2％ |
| Grape seed oil | 0.1 | 0.1％ |
| Sorbitol | 0.34 | 0.34％ |
| 1, 2- |
1 | 1％ |
| Vitamin E | 0.02 | 0.02％ |
| Glycerol | 0.34 | 0.34％ |
| Triethanolamine | 0.02 | 0.02％ |
| Deionized water | Make up to 100 | Make up to 100% |
The preparation method comprises the following steps:
(1) preparing raw materials according to a raw material formula;
(2) adding deionized water into a container, adding other raw materials, mixing, and homogenizing for 2 min;
(3) standing for 0.5h, canning, packaging, and using with bubbling bottle.
Examples 2 to 8
The procedure was carried out in substantially the same manner as in example 1 except that the components shown in Table 2 below, such as rose extract, polyhexamethyleneguanidine hydrochloride, dodecyldimethylbetaine, etc., were added in different amounts.
Table 2 examples 2-8 materials and amounts thereof used to prepare hand sanitizers
Note: in the table, "-" represents the same as in example 1.
According to the hand sanitizer prepared in the embodiment of the invention, sensory indexes, pH values and stability are detected according to a detection method required in GB19877.1-2005 special hand sanitizer sanitary specifications; and (4) measuring the sterilization rate and the bacteriostasis rate according to the GB15979-2002 standard.
The bacteriostatic effect of the product is determined by adopting a bacteriostatic zone test, and the method comprises the following steps: 0.1mL of suspension liquid (OD) is sucked by a pipette gun6000.25) on LB solid medium, evenly spreading, putting round filter paper (diameter 14mm) soaked with the liquid soap product into the center of the LB solid medium, inverting the culture dish for constant-temperature culture (37 ℃, 16h), and measuring the diameter of the inhibition zone. The larger the diameter of the inhibition zone is, the better the inhibition effect is.
The product was pumped out of the same volume through a bubble bottle, timed with a timer, and the time required for the foam to develop to completely dissipate was counted to assess foam stability. The longer the time required for dissipation, the better the foam stability is reflected, and the longer the lotion remains foamy on the hands before rubbing.
The results of the hand sanitizer tests obtained in examples 1-8 are shown in Table 3 and FIG. 1, FIG. 2, and FIG. 3.
TABLE 3 sensory indices and bacteriostatic effects of examples 1-8
Note: the time required for the foam to dissipate means the time required for a foam mass of 4cm in diameter to completely dissipate at normal temperature and pressure.
As can be seen from the results of fig. 1 to 3 and table 3:
(1) the pH values of the products of examples 1-8 are in the range of 4-10 (Table 3), which all accord with the GB19877.1-2005 regulations, and the appearance and the stability of the products all accord with the GB19877.1-2005 requirements.
(2) Example 4, example 8 without rose extract addition, the product had no rose aroma, while other example products with rose extract addition had rose aroma (table 3).
(3) In example 2, the rose extract is added, but in example 8, no rose extract is added, and the comparison of the detection results of the product for inhibiting staphylococcus aureus shows that (fig. 3), the staphylococcus aureus in example 8 has a small inhibition zone and a weak inhibition effect, while the staphylococcus aureus in example 2 has a diameter of 22mm and a large inhibition zone, which reflects that the rose extract has a remarkable inhibition effect on staphylococcus aureus.
(4) The difference between the examples 1 and 3 lies in that the addition amount of the polyhexamethylene guanidine hydrochloride serving as the auxiliary bactericide is 0.25mL, 0mL and 0.13mL respectively, and the bacteriostatic effect of the comparative product is found (figure 2 and figure 3), the product of the example 1 has significant bacteriostatic effects on escherichia coli and staphylococcus aureus (the diameter of a bacteriostatic circle is 20-21mm), which shows that the higher-concentration auxiliary bactericide has better bacteriostatic effect and has a gain auxiliary effect on the bacteriostatic effect of the rose extract.
(5) The difference among the examples 1, 4 and 5 lies in that the addition amount of the rose extract is 16mL, 0mL and 32mL respectively, the bacteriostatic effect of the comparative product on staphylococcus aureus is found (figure 3), the product in the example 5 has the best bacteriostatic effect on staphylococcus aureus, the bacteriostatic zone reaches 32mm, and the optimal addition amount of the rose extract with 32mL is reflected.
(6) Examples 1, 6, and 7 differ in that the blowing agent dodecyl dimethyl betaine is added in an amount of 2mL, 0.5mL, and 4mL, respectively, and the foam stability of the comparative product (table 3, fig. 1) is found to produce stable foam (the time required for foam dissipation is greater than 3min), but the foam of example 6 has high water content and poor fineness, while the foam of example 1 has fine and good stability, indicating that the addition amount of 2mL dodecyl dimethyl betaine is optimal.
Combining the above results, it is speculated that the more optimized product formulation has the following components and volume percentages: 32% of rose extract, 2% of dodecyl dimethyl betaine, 0.5% of polyhexamethylene guanidine hydrochloride, 0.2% of roxburgh rose extract, 0.1% of grape seed oil, 1, 2-propylene glycol, 0.34% of sorbitol, 0.34% of glycerol, 0.02% of vitamin E, 0.02% of triethanolamine and the balance of water (deionized water). Thus, the invention prepares and tests the technical effect of this formulation in example 9 below.
Example 9
The amount of hand sanitizer prepared in this example was 100mL, prepared according to the optimized product formulation described above, as shown in table 4 below.
TABLE 4 materials and amounts used in preparation of hand sanitizers of example 9
| Name of raw materials | Volume (mL) | Volume percent |
| Rose extract | 32 | 32％ |
| Polyhexamethylene guanidine hydrochloride | 0.5 | 0.5％ |
| |
2 | 2％ |
| Rosa roxburghii extract | 0.2 | 0.2％ |
| Grape seed oil | 0.1 | 0.1％ |
| Sorbitol | 0.34 | 0.34％ |
| 1, 2- |
1 | 1％ |
| Vitamin E | 0.02 | 0.02％ |
| Glycerol | 0.34 | 0.34％ |
| Triethanolamine | 0.02 | 0.02％ |
| Deionized water | Make up to 100 | Make up to 100% |
The preparation method comprises the following steps:
(1) preparing raw materials according to a raw material formula;
(2) adding deionized water into a container, adding other raw materials, mixing, and homogenizing for 2 min;
(3) standing for 0.5h, canning and packaging, and using in combination with bubbling bottle.
The optimized product appearance, smell, stability and pH value of example 9 are determined with reference to the test method required in GB19877.1-2005 special hand sanitizer sanitation specifications; and measuring the freshness, dryness and skin care effect of hands after use by sensory measurement. The results are given in Table 5 below.
TABLE 5 Properties and Effect of the hand sanitizer made in example 9
The optimized product of the example 9 is subjected to sterilization rate and bacteriostasis rate measurement according to the standard of GB15979-2002, namely: after mixing with the suspension, the suspension was treated with a neutralizer and then applied to the medium, and the negative control was untreated suspension, the results are shown in FIG. 4. Tests show that the hand sanitizer of the embodiment has the sterilization rate of 100% on escherichia coli and staphylococcus aureus, no bacteria grow on a culture medium, and the bacteriostatic effect is very excellent.
Referring to the inhibition zone test method, the hand sanitizer of example 9 and 3 commercial hand sanitizers (Hualupai hand sanitizer, Condaler hand sanitizer and Duolu brand hand sanitizer) were compared in terms of inhibition effect of Escherichia coli, that is, the hand sanitizer of example 9 and the 3 commercial hand sanitizer of the same volume were used to soak a sterile circular filter paper sheet (diameter 14mm), the negative control was a sterile water soaked circular filter paper sheet, the circular filter paper sheet was attached to the center of a culture medium containing a suspension liquid of the same concentration, and cultured at 37 ℃ for 16h, and the size of the inhibition zone was determined, and the detection result is shown in FIG. 5. As a result, the diameters (21mm) of the inhibition zones of the hand sanitizer prepared in the example 9 on Escherichia coli are larger than those (15mm) of the Hualu brand hand sanitizer (19mm), the Kangdali hand sanitizer (14mm) and the Dilu brand hand sanitizer on the market, and the excellent inhibition effect of the hand sanitizer prepared in the example is reflected.
The hand sanitizer disclosed by the invention has excellent bacteriostatic effect, and the combination of citronellol, phenethyl alcohol and the like in the rose extract has a bacteriostatic effect and polyhexamethylene guanidine hydrochloride is used as an auxiliary material in the hand sanitizer disclosed by the invention, so that the key bacteriostatic effect is achieved. The hand sanitizer also has an excellent skin care effect, which is mainly attributed to the following components playing the skin care effect: natural active substances in rose extract and Rosa roxburghii Tratt extract, grape seed oil, vitamin E, etc. The hand sanitizer also has the functions of moistening and preserving moisture, which are mainly attributed to glycerin, 1, 2-propylene glycol and sorbitol. The hand sanitizer disclosed by the invention has a very excellent foaming effect, which is mainly attributed to the fact that the foaming agent dodecyl dimethyl betaine is used, and the dodecyl dimethyl betaine serving as a surfactant also has a very good decontamination effect. In addition, the triethanolamine can adjust the pH value, keep the pH value in a range close to the pH value of human skin and prevent the stimulation of the use part.
The preparation method of the hand sanitizer provided by the invention is simple, the hand sanitizer can be prepared by mixing and homogenizing all the components, and the production operation is easy. The preparation process can be seen in FIG. 6; the product and its use effect can be seen in fig. 7.
Finally, it should be noted that: the above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. The rose wash-free antibacterial skin-care foam type hand sanitizer is characterized by comprising the following components: rose extract, polyhydric alcohol, foaming agent, auxiliary bactericide, water and pH regulator.
2. The hand sanitizer according to claim 1, wherein:
the rose extract is rose hydrosol and/or rose essential oil;
the polyhydric alcohol is at least one selected from the group consisting of glycerin, 1, 2-propanediol, and sorbitol;
the foaming agent is dodecyl dimethyl betaine;
the bactericide is polyhexamethylene guanidine hydrochloride;
the water is deionized water and/or distilled water; and/or
The pH regulator is triethanolamine.
3. The hand sanitizer of claim 1 or 2, further comprising: rosa roxburghii extract; grape seed oil; a vitamin E; 1, 2-propanediol; and/or sorbitol.
4. A hand sanitizer according to any one of claims 1 to 3, wherein:
the polyol comprises glycerol.
5. A hand sanitizer according to any one of claims 1 to 4,
the hand sanitizer comprises the following components in percentage by volume: 16-35% of rose extract, 0.1-1.5% of glycerol, 0.5-4% of foaming agent, 0.25-0.5% of bactericide, 0.01-0.1% of pH regulator, 0-0.5% of roxburgh rose extract, 0-0.5% of grape seed oil, 0-0.5% of vitamin E, 0-1% of 1, 2-propylene glycol and 0-1% of sorbitol.
6. A hand sanitizer according to any one of claims 1 to 5, wherein:
the polyol further comprises 1, 2-propanediol and/or sorbitol.
7. The hand sanitizer according to any one of claims 1 to 5, wherein the composition of the hand sanitizer is as follows, in volume percent of the hand sanitizer: 16-35% of rose extract, 0.1-1.5% of glycerol, 0.5-4% of foaming agent, 0.25-0.5% of bactericide, 0.01-0.1% of pH regulator, 0.1-0.5% of roxburgh rose extract, 0.05-0.5% of grape seed oil, 0.01-0.5% of vitamin E, 0.1-1% of 2-propylene glycol, 0.1-1% of sorbitol and the balance of water.
8. A method of preparing a foamed hand sanitizer according to claims 1 to 7, comprising the steps of:
(1) measuring various components of the hand sanitizer;
(2) adding water into a container at normal temperature, and then adding all the components into the water to be uniformly mixed;
(3) standing for 0.2-1.5h to obtain the hand sanitizer;
preferably, after the step (3), the step of filling the hand sanitizer into a bubbling bottle is further included.
9. The method according to claim 8, wherein the ratio of each component is as follows: 16-35% of rose extract, 0.34% of glycerol, 0.5-4% of dodecyl dimethyl betaine, 0.25-0.5% of polyhexamethylene guanidine hydrochloride, 0.02% of triethanolamine, 0.2% of rosa roxburghii tratt extract, 0.1% of grape seed oil, 0.02% of vitamin E, 0.1% of 1, 2-propylene glycol, 0.34% of sorbitol and the balance of water.
10. The use of a hand sanitizer according to any one of claims 1 to 7 or a hand sanitizer made by the process of claim 8 or 9 in the leave-on disinfection of corresponding microorganisms.
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