CN113845354A

CN113845354A - Preparation method of nicotine salt atomizer with low irritation

Info

Publication number: CN113845354A
Application number: CN202111211016.3A
Authority: CN
Inventors: 邹阳; 邹军; 刘梅森; 罗维贤; 刘若男; 吕浩
Original assignee: Shenzhen Zinwi Biotech Co Ltd
Current assignee: Shenzhen Zinwi Biotech Co Ltd
Priority date: 2021-10-18
Filing date: 2021-10-18
Publication date: 2021-12-28

Abstract

The invention discloses a preparation method of a nicotine salt atomizer with small irritation, in particular to the technical field of atomizer preparation methods, the invention arranges a low-melting metal core film in the center of a ceramic atomizing core, and implants a conductive piece in the ceramic atomizing core, so that the conductive piece and the ceramic atomizing core are combined more tightly and are not easy to fall off, meanwhile, the arrangement of an anti-blocking coating can solve the problem of blockage, the effective atomizing rate can be obviously improved, and by arranging a conductive film layer and a far infrared coating, the heat conduction capability of a far infrared coating is greatly improved by adding silver powder, the heating effect is better, meanwhile, the nicotine salt microcapsule particles are arranged in the far infrared coating, so that the fragrance is more mellow, the irritation of nicotine can be obviously reduced, and simultaneously, the nicotine salt microcapsule particles can enter blood more easily, thereby being absorbed by human bodies more easily to achieve the effect of relieving smoking addiction, and further controlling the volatilization speed of composite nicotine salt, thereby having lasting smoking cessation effect.

Description

Preparation method of nicotine salt atomizer with low irritation

Technical Field

The invention relates to the technical field of atomizer preparation methods, in particular to a preparation method of a nicotine salt atomizer with low irritation.

Background

With the development of society, tobacco is gradually replaced as a consumer product harmful to human body, for example, recently, an electronic atomization product is developed, which atomizes liquid containing chemical substances such as nicotine by a high-tech means to generate smoke to simulate the smoking purpose, which not only does not harm the health of smokers, but also reduces the pollution to environment, and in the electronic atomization product, a necessary core component is an atomizer, in order to reduce the harm of the atomizer to human body in the process of atomizing nicotine salt, in the prior art, microporous ceramic is generally prepared by using microporous ceramic to the atomizer, and a microporous ceramic body is formed by pressing inorganic ceramic microspheres in a molten or semi-molten state through a mold, so that the structure is stable, the microporous ceramic body has a regular shape, and cellular micropores formed by accumulating particles are arranged on the surface and inside, thereby dispersing the nicotine salt and reducing the stimulation to human body during the atomization of nicotine salt, but atomizer among the prior art is blockked up easily and influence normal use when in-service use, and because porous ceramic body has the micropore, make porous ceramic body surface relatively more crude, lead to the heating element adhesive force relatively poor, make resistance stability and the homogeneity of the heating circuit that forms through printing and sintering not enough, and the electronic atomization equipment that the low temperature that produces through the atomizer on the market heats the pipe tobacco and toasts generally realizes heating through the resistance heating piece of heating pipe bottom, adopt this kind of heating method, there are the problem that heating efficiency is low and heat inhomogeneous, and only simple atomizing function, do not have the effect of quiing smoking.

Disclosure of Invention

In order to overcome the defects in the prior art, the invention provides a preparation method of a nicotine salt atomizer with low irritation, and the technical problems to be solved by the invention are as follows: atomizer among the prior art is blockked up easily and influence normal use when in-service use, and because porous ceramic body has the micropore, make porous ceramic body surface relatively more crude, lead to the heating element adhesive force relatively poor, make resistance stability and the homogeneity of the heating circuit that forms through printing and sintering not enough, and the low temperature that produces through the atomizer on the market heats the electronic atomization equipment that toasts to the pipe tobacco and generally realizes heating through the resistance heating piece of heating pipe bottom, adopt this kind of heating methods, there are the low and inhomogeneous problem of heating efficiency, and only simple atomizing function, do not have the problem of the effect of quiing smoking.

In order to achieve the purpose, the invention provides the following technical scheme: a method of making a low-irritation nicotine salt nebulizer, comprising the steps of:

s1, weighing 35-55 parts by weight of ceramic powder with hydroxyl group compounds, 15-20 parts by weight of diatomite and 25-35 parts by weight of inorganic glass microspheres, placing the ceramic powder, the diatomite and the inorganic glass microspheres in a mixer for mixing treatment, weighing 25-45 parts by weight of pore-forming agent after uniform mixing, adding the pore-forming agent for continuous mixing, preparing a blank A according to the shape design after mixing, weighing 80-90 parts by weight of ceramic powder and 10-20 parts by weight of pore-forming agent for mixing, forming a blank B according to the shape design, superposing the obtained blank A and the blank B together, inserting a heating element into one side of the blank B far away from the blank A, and then placing the blank B in a high-temperature sintering device for high-temperature sintering to form a mixed blank with molten microspheres, thus obtaining the ceramic atomizing core.

S2, placing the obtained ceramic atomization core in a mould, placing the low-melting-point metal core film in the center of the ceramic atomization core to obtain the anti-blocking coating, implanting conductive member into the porous ceramic atomizer to obtain a molded porous ceramic atomizer, weighing 5-10 parts of sodium carboxymethylcellulose and 10-15 parts of N, N-dimethylacetamide, pouring into a mixer, stirring to obtain a mixed solution A, grinding conductive graphite into powder smaller than 500 meshes, and then pouring graphite powder into the mixed solution A, mixing again to obtain mixed solution B, then uniformly mixing the modified far infrared powder and 1-2 parts of silver powder, then adding 5-10 parts of stannic chloride, 3-5 parts of wetting dispersant, 3-6 parts of solvent and 2-5 parts of film-forming assistant, and continuously mixing to obtain mixed solution C.

S3, uniformly mixing 5-10 parts by weight of benzoic acid, 5-10 parts by weight of linolenic acid, 5-30 parts by weight of linoleic acid, 3-5 parts by weight of citric acid, 5-6 parts by weight of malic acid and 1-2 parts by weight of ascorbic acid to obtain a mixed solution D, uniformly mixing squalene and squalane to obtain a mixed solution E, pouring the mixed solution D into the mixed solution E, adding nicotine base, heating and stirring for full reaction to obtain a mixed solution F, uniformly mixing 10-20 parts by weight of beta-cyclodextrin and 10-15 parts by weight of deionized water, stirring at 50-60 ℃ at a speed of 100r/min for 1-3h, adding 6-10 parts by weight of Arabic gum, and continuously stirring at a speed of 50-100r/min for 10-20 min.

S4, after the solution is cooled to 35-40 ℃, standing for 18-24h at 1-6 ℃ to obtain a wrapping liquid, then uniformly spraying the wrapping liquid on the surface of the mixed liquid F to obtain microcapsule particles, uniformly mixing the obtained microcapsule particles with the mixed liquid F to obtain a mixed liquid G, drying and blowing dust to wipe the obtained porous ceramic, uniformly coating the obtained mixed liquid B on the surface of the treated porous ceramic to form a conductive film layer after drying, uniformly coating the obtained mixed liquid G on the surface of the conductive film layer, and drying to form a far infrared coating to obtain the finished product of the nicotine salt atomizer.

As a further scheme of the invention: the average pore diameter of the inorganic glass microspheres is 5-25 μm, and the average pore diameter of the diatomite is 5-50 μm.

As a further scheme of the invention: the metal core film is Sn-1Ag-0.5Cu with the diameter of 1 mm.

As a further scheme of the invention: the temperature of the constant temperature box is set to be 190-200 ℃, and the curing time is set to be 130-160 min.

As a further scheme of the invention: the temperature of the resistance furnace is set to be 270-280 ℃, the melting temperature is 30-40min, and the temperature is kept for 1-2 h.

As a further scheme of the invention: the viscosity of the mixed liquid B and the mixed liquid C is 0.5-1.5Pa, and the coating thickness is controlled between 5-30 mu m.

As a further scheme of the invention: the preparation method of the modified far infrared powder comprises the following steps: adding a modifier into an ethanol water solution with the volume fraction of 50% according to the mass ratio of 1:20, uniformly mixing to obtain a modifier solution, adding the far infrared powder into the modifier solution, heating to 65 ℃, ultrasonically stirring for 25 minutes to obtain a mixed solution, filtering the mixed solution to obtain a filter cake, washing the filter cake with water, and drying in an oven at 80 ℃ to obtain the modified far infrared powder.

As a further scheme of the invention: the ceramic powder doped with the compound with the hydroxyl group comprises the following components in parts by weight: 70-80 of main blank, 10-15 of albite, 10-15 of plastic clay and 1-5 of hydroxyapatite.

As a further scheme of the invention: the main blank comprises one or more of alumina, silica, silicon carbide, cordierite, silicon nitride, aluminum nitride and mullite, the pore-forming agent comprises at least one of wood chips, charcoal, glucose, cellulose, starch, graphite, PS microspheres and PMMA microspheres, and the particle size of the pore-forming machine is 200-300 meshes.

The invention has the beneficial effects that:

the invention arranges the low melting point metal core film in the center of the ceramic atomizing core and implants the conductive piece in the ceramic atomizing core, so that the conductive piece is combined with the ceramic atomizing core more tightly, the stability and the uniformity of the resistance value of the resistor are ensured to be higher, and the ceramic atomizing core is not easy to fall off, meanwhile, the obtained ceramic atomizing core is arranged in the die, and the low melting point metal core film is arranged in the center of the ceramic atomizing core, so that the anti-blocking coating with good heat insulation effect is obtained, thereby solving the blocking problem, obviously improving the effective atomizing rate, and the conductive film layer and the far infrared coating are arranged, so that the far infrared coating is electrified after the conductive film layer is electrically connected with an external power supply when the atomizer is used, and the far infrared coating generates stronger far infrared radiation after being electrified so as to heat and atomize the tobacco shreds, and the heat conduction capability of the far infrared coating is greatly improved by adding the silver powder, the heating speed is higher, the heating is more uniform, the heating effect is better, meanwhile, the far-infrared coating is internally provided with nicotine salt microcapsule particles, the far-infrared coating can emit enough tobacco flavor when in use, the flavor is more pure and mild, the natural organic acid in the far-infrared coating can obviously reduce the irritation of nicotine, meanwhile, the composite nicotine salt disclosed by the invention can enter the blood more easily, so that the composite nicotine salt can be absorbed by a human body more easily to achieve the effect of relieving the smoking addiction, the beta-cyclodextrin is adopted to wrap the essence extract, meanwhile, the Arabic gum is added to make up the disadvantage of poor emulsifying property of the beta-cyclodextrin, the release of essence components is further hindered by adding active carbon, the phenomenon of oxidative deterioration of the composite nicotine salt due to the influence of light and heat can be effectively generated, and the volatilization speed of the composite nicotine salt can be further controlled, thereby improving the durability and stability of the release of the compound nicotine salt and having lasting smoking cessation effect.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

a method of making a low-irritation nicotine salt nebulizer, comprising the steps of:

S2, placing the obtained ceramic atomization core in a mold, implanting a conductive piece outside the ceramic atomization core to obtain a formed porous ceramic atomizer, weighing 5-10 parts of sodium carboxymethylcellulose and 10-15 parts of N, N-dimethylacetamide, pouring the mixture into a mixer, uniformly stirring to obtain a mixed solution A, grinding conductive graphite into powder with a size smaller than 500 meshes, pouring graphite powder into the mixed solution A, mixing again to obtain a mixed solution B, modifying the far infrared powder, uniformly mixing with 1-2 parts of silver powder, adding 5-10 parts of stannic chloride, 3-5 parts of wetting dispersant, 3-6 parts of solvent and 2-5 parts of film forming auxiliary agent, and continuously mixing to obtain a mixed solution C.

The average pore diameter of the inorganic glass microspheres is 5-25 μm, and the average pore diameter of the diatomite is 5-50 μm.

The temperature of the constant temperature box is set to be 190-200 ℃, and the curing time is 130-160 min.

The temperature of the resistance furnace is set to be 270-280 ℃, the melting temperature is 30-40min, and the temperature is kept for 1-2 h.

The viscosity of the mixed liquid B and the mixed liquid C is 0.5-1.5Pa, and the coating thickness is controlled between 5-30 μm.

The preparation method of the modified far infrared powder comprises the following steps: adding a modifier into an ethanol water solution with the volume fraction of 50% according to the mass ratio of 1:20, uniformly mixing to obtain a modifier solution, adding the far infrared powder into the modifier solution, heating to 65 ℃, ultrasonically stirring for 25 minutes to obtain a mixed solution, filtering the mixed solution to obtain a filter cake, washing the filter cake with water, and drying in an oven at 80 ℃ to obtain the modified far infrared powder.

The ceramic powder doped with the compound with the hydroxyl group comprises the following components in parts by weight: 70-80 of main blank, 10-15 of albite, 10-15 of plastic clay and 1-5 of hydroxyapatite.

The main blank comprises one or more of alumina, silica, silicon carbide, cordierite, silicon nitride, aluminum nitride and mullite, the pore-forming agent comprises at least one of wood chips, charcoal, glucose, cellulose, starch, graphite, PS microspheres and PMMA microspheres, and the particle size of the pore-forming machine is 200-300 meshes.

Example 2:

S2, placing the obtained ceramic atomization core in a mold, placing a low-melting-point metal core film in the center of the ceramic atomization core to obtain an anti-blocking coating, implanting a conductive piece into the anti-blocking coating to obtain a formed porous ceramic atomizer, weighing 5-10 parts of stannic chloride, 3-5 parts of wetting dispersant, 3-6 parts of solvent and 2-5 parts of film-forming assistant, and continuously mixing to obtain mixed liquid C.

S3, uniformly mixing 5-10 parts by weight of benzoic acid, 5-10 parts by weight of linolenic acid, 5-30 parts by weight of linoleic acid, 3-5 parts by weight of citric acid, 5-6 parts by weight of malic acid and 1-2 parts by weight of ascorbic acid to obtain a mixed solution D, then adding nicotine base, heating while stirring for sufficient reaction to obtain a mixed solution F, uniformly mixing 10-20 parts by weight of beta-cyclodextrin and 10-15 parts by weight of deionized water, stirring for 1-3 hours at the speed of 200r/min at the temperature of 50-60 ℃, adding 6-10 parts by weight of Arabic gum, and continuously stirring for 10-20 minutes at the speed of 50-100 r/min.

S4, after the solution is cooled to 35-40 ℃, standing for 18-24h at 1-6 ℃ to obtain a wrapping liquid, then uniformly spraying the wrapping liquid on the surface of the mixed liquid F to obtain microcapsule particles, uniformly mixing the obtained microcapsule particles with the mixed liquid F to obtain a mixed liquid G, drying and blowing dust to wipe the obtained porous ceramic, then uniformly coating the obtained mixed liquid G on the surface of a conductive film, and drying to form a coating to obtain the finished product of the nicotine salt atomizer.

The metal core film is Sn-1Ag-0.5Cu with the diameter of 1 mm.

The viscosity of the mixed solution C is 0.5-1.5Pa, and the coating thickness is controlled between 5-30 μm.

Example 3:

S3, uniformly mixing squalene and squalane to obtain a mixed solution E, pouring the mixed solution D into the mixed solution E, adding nicotine alkali, and heating while stirring for full reaction to obtain a mixed solution F.

And S4, drying and soot blowing wiping the obtained porous ceramic, uniformly coating the obtained mixed solution B on the surface of the treated porous ceramic, drying to form a conductive film layer, uniformly coating the obtained mixed solution F on the surface of the conductive film layer, and drying to form a far infrared coating to obtain the finished product of the nicotine salt atomizer.

The metal core film is Sn-1Ag-0.5Cu with the diameter of 1 mm.

Comparative example 1:

the atomizer is prepared by a preparation method common in the prior art.

The following table is obtained according to examples 1 to 3 and comparative example 1:

from the comparison in the table above, it can be seen that: the invention arranges the low melting point metal core film in the center of the ceramic atomizing core and implants the conductive piece in the ceramic atomizing core, so that the conductive piece is combined with the ceramic atomizing core more tightly, the stability and the uniformity of the resistance value of the resistor are ensured to be higher, and the ceramic atomizing core is not easy to fall off, meanwhile, the obtained ceramic atomizing core is arranged in the die, and the low melting point metal core film is arranged in the center of the ceramic atomizing core, so that the anti-blocking coating with good heat insulation effect is obtained, thereby solving the blocking problem, obviously improving the effective atomizing rate, and the conductive film layer and the far infrared coating are arranged, so that the far infrared coating is electrified after the conductive film layer is electrically connected with an external power supply when the atomizer is used, and the far infrared coating generates stronger far infrared radiation after being electrified so as to heat and atomize the tobacco shreds, and the heat conduction capability of the far infrared coating is greatly improved by adding the silver powder, the heating speed is higher, the heating is more uniform, the heating effect is better, meanwhile, the far-infrared coating is internally provided with nicotine salt microcapsule particles, the far-infrared coating can emit enough tobacco flavor when in use, the flavor is more pure and mild, the natural organic acid in the far-infrared coating can obviously reduce the irritation of nicotine, meanwhile, the composite nicotine salt disclosed by the invention can enter the blood more easily, so that the composite nicotine salt can be absorbed by a human body more easily to achieve the effect of relieving the smoking addiction, the beta-cyclodextrin is adopted to wrap the essence extract, meanwhile, the Arabic gum is added to make up the disadvantage of poor emulsifying property of the beta-cyclodextrin, the release of essence components is further hindered by adding active carbon, the phenomenon of oxidative deterioration of the composite nicotine salt due to the influence of light and heat can be effectively generated, and the volatilization speed of the composite nicotine salt can be further controlled, thereby improving the durability and stability of the release of the compound nicotine salt and having lasting smoking cessation effect.

The points to be finally explained are: although the present invention has been described in detail with reference to the general description and the specific embodiments, on the basis of the present invention, the above embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A method for preparing a nicotine salt atomizer with low irritation, which is characterized by comprising the following steps:

s1, weighing 35-55 parts by weight of ceramic powder with hydroxyl group compounds, 15-20 parts by weight of diatomite and 25-35 parts by weight of inorganic glass microspheres, placing the ceramic powder, the diatomite and the inorganic glass microspheres in a mixer for mixing treatment, after mixing uniformly, weighing 25-45 parts by weight of pore-forming agent, adding the pore-forming agent for continuous mixing, after mixing is completed, preparing a blank A according to the shape design, meanwhile weighing 80-90 parts by weight of ceramic powder and 10-20 parts by weight of pore-forming agent, mixing, then forming a blank B according to the shape design, superposing the obtained blank A and the blank B together, inserting a heating element into one side of the blank B, which is far away from the blank A, and then placing the blank B in a high-temperature sintering device for high-temperature sintering to form a mixed blank with molten microspheres, thus obtaining a ceramic atomizing core;

s2, placing the obtained ceramic atomization core in a mould, placing the low-melting-point metal core film in the center of the ceramic atomization core to obtain the anti-blocking coating, implanting conductive member into the porous ceramic atomizer to obtain a molded porous ceramic atomizer, weighing 5-10 parts of sodium carboxymethylcellulose and 10-15 parts of N, N-dimethylacetamide, pouring into a mixer, stirring to obtain a mixed solution A, grinding conductive graphite into powder smaller than 500 meshes, then pouring graphite powder into the mixed solution A, mixing again to obtain mixed solution B, then uniformly mixing the modified far infrared powder with 1-2 parts of silver powder, then adding 5-10 parts of stannic chloride, 3-5 parts of wetting dispersant, 3-6 parts of solvent and 2-5 parts of film-forming assistant, and continuously mixing to obtain mixed solution C;

s3, uniformly mixing 5-10 parts by weight of benzoic acid, 5-10 parts by weight of linolenic acid, 5-30 parts by weight of linoleic acid, 3-5 parts by weight of citric acid, 5-6 parts by weight of malic acid and 1-2 parts by weight of ascorbic acid to obtain a mixed solution D, uniformly mixing squalene and squalane to obtain a mixed solution E, pouring the mixed solution D into the mixed solution E, adding nicotine base, heating while stirring for full reaction to obtain a mixed solution F, uniformly mixing 10-20 parts by weight of beta-cyclodextrin and 10-15 parts by weight of deionized water, stirring at 50-60 ℃ at a speed of 100-200r/min for 1-3h, adding 6-10 parts by weight of acacia, and continuously stirring at a speed of 50-100r/min for 10-20 min;

2. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the average pore diameter of the inorganic glass microspheres is 5-25 μm, and the average pore diameter of the diatomite is 5-50 μm.

3. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the metal core film is Sn-1Ag-0.5Cu with the diameter of 1 mm.

4. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the temperature of the constant temperature box is set to be 190-200 ℃, and the curing time is set to be 130-160 min.

5. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the temperature of the resistance furnace is set to be 270-280 ℃, the melting temperature is 30-40min, and the temperature is kept for 1-2 h.

6. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the viscosity of the mixed liquid B and the mixed liquid C is 0.5-1.5Pa, and the coating thickness is controlled between 5-30 mu m.

7. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the preparation method of the modified far infrared powder comprises the following steps: adding a modifier into an ethanol water solution with the volume fraction of 50% according to the mass ratio of 1:20, uniformly mixing to obtain a modifier solution, adding the far infrared powder into the modifier solution, heating to 65 ℃, ultrasonically stirring for 25 minutes to obtain a mixed solution, filtering the mixed solution to obtain a filter cake, washing the filter cake with water, and drying in an oven at 80 ℃ to obtain the modified far infrared powder.

8. A method of manufacturing a nicotine salt nebulizer as claimed in claim 1, with low irritation, comprising: the ceramic powder doped with the compound with the hydroxyl group comprises the following components in parts by weight: 70-80 of main blank, 10-15 of albite, 10-15 of plastic clay and 1-5 of hydroxyapatite.

9. A method of manufacturing a nicotine salt nebulizer as claimed in claim 8, wherein the method comprises the steps of: the main blank comprises one or more of alumina, silica, silicon carbide, cordierite, silicon nitride, aluminum nitride and mullite, the pore-forming agent comprises at least one of wood chips, charcoal, glucose, cellulose, starch, graphite, PS microspheres and PMMA microspheres, and the particle size of the pore-forming machine is 200-300 meshes.