CN110477442A - A kind of preparation method and application of compound nicotine salt and electronics tobacco tar - Google Patents
A kind of preparation method and application of compound nicotine salt and electronics tobacco tar Download PDFInfo
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- CN110477442A CN110477442A CN201910796592.5A CN201910796592A CN110477442A CN 110477442 A CN110477442 A CN 110477442A CN 201910796592 A CN201910796592 A CN 201910796592A CN 110477442 A CN110477442 A CN 110477442A
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
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Abstract
The present invention relates to a kind of compound nicotine salt and its preparation method and applications of electronics tobacco tar.The compound nicotine salt is made by following raw material: organic acid 40-60 parts by weight, nicotine 40-60 parts by weight, the organic acid are made of organic acids such as benzoic acid, linolenic acid, linoleic acid, citric acid, malic acid, ascorbic acid.Organic acid used in the present invention passes through suitable proportion, the irritation of nicotine can be significantly reduced, the nicotine salt of formation generates the fragrance after similar natural baccy burning in sucking, the nicotine salt and suitable diluent match, diluent is made of glycerine, propylene glycol, squalene and saualane, and reconciling into electronics tobacco tar may be directly applied to electronic smoke atomizer.The fragrance of compound nicotine salt of the present invention closer to traditional cigarette, release that smoking addiction effect is more preferable, safety in utilization is higher.
Description
Technical field
The invention belongs to electronic cigarette technical fields, and in particular to a kind of electronics tobacco tar preparation side of compound nicotine salt solution
Method and application.
Background technique
Electronic cigarette is a kind of electronic product for imitating cigarette, there is appearance, smog, taste and the feeling as cigarette.
It is by the means such as atomization, after liquid nicotine salt is become steam, a kind of product for allowing user to suck.The structure of electronic cigarette
Main includes the smoke pipe, vaporising device and battery three parts for holding liquid nicotine salt.The liquid nicotine salt electronics tobacco tar
It is the key that electronic cigarette sucking quality, fragrance, releasing smoking addiction effect and the use after existing liquid nicotine salt is sucked are pacified
Full property is not highly desirable.
Summary of the invention
In order to solve the above-mentioned problems in the prior art, the present invention provide a kind of fragrance closer to traditional cigarette,
Release that smoking addiction effect is more preferable, the higher compound nicotine salt of safety in utilization and preparation method thereof.
The technical solution of the present invention is as follows:
A kind of compound nicotine salt, is made by following raw material: organic acid 40-60 parts by weight, nicotine alkali 40-60 weight
Part, the organic acid is made of benzoic acid, linolenic acid, linoleic acid, citric acid, malic acid and ascorbic acid.
The preparation method of the compound nicotine salt, specific steps are as follows: by benzoic acid, linolenic acid, linoleic acid, citric acid,
Malic acid and ascorbic acid are uniformly mixed, and obtain mixture S1；Squalene and saualane are uniformly mixed, mixture S2 is obtained；
Mixture S2 is poured into mixture S1, nicotine alkali is then added, heat while stirring make sufficiently react to get.
Further, the speed of the stirring is 50-100rpm, and the temperature that is heated to is 50-90 DEG C.
Further, the organic acid is composed of the following components by mass percentage: benzoic acid 10-20%, linolenic acid 10-
20%, linoleic acid 10-60%, citric acid 5-10%, malic acid 10-20%, ascorbic acid 1-2%.
Further, the organic acid is composed of the following components by mass percentage: benzoic acid 20%, linolenic acid 10%,
Linoleic acid 50%, citric acid 9%, malic acid 10%, ascorbic acid 1%.
A kind of electronics tobacco tar based on the compound nicotine salt, further includes diluent, the diluent with it is described compound
The mass ratio of nicotine salt is 60-40:40-60.
Preparation method of the electronic cigarette with compound nicotine salt solution, specific steps are as follows: by benzoic acid, linolenic acid, Asia
Oleic acid, citric acid, malic acid, ascorbic acid are uniformly mixed, and obtain mixture S1；Squalene and saualane are uniformly mixed, obtained
To mixture S2；Mixture S2 is poured into mixture S1, nicotine alkali is then added, heating while stirring makes sufficiently to react,
Nicotine salt first product is obtained, it is 40-60% that the nicotine salt first product, which is diluted to mass percent concentration with diluent, i.e.,
.
Further, the diluent is glycerine, propylene glycol, squalene and saualane.
Further, the mass ratio of the glycerine, propylene glycol, squalene and saualane is 1-5:1-5:1-5:1-5.
Application of the compound nicotine salt solution in electronic cigarette.
The invention has the benefit that
Compound nicotine salt of the present invention is reacted by organic acid and nicotine and is made, and the organic acid is by benzoic acid, Asia
Numb acid, linoleic acid, citric acid, malic acid, ascorbic acid composition.Wherein, linoleic acid, linolenic acid can increase the concentration of flue gas,
Tobacco flavor is improved, it is compound with benzoic acid, citric acid, malic acid, ascorbic acid, pH value can be adjusted, the stimulation of nicotine is weakened,
Improve into larynx smooth degree, makes that fragrance is more pure and mild, aftertaste is more sweet.Organic acid used in the present invention is largely naturally occurring
Ingredient in tobacco can significantly reduce the irritation of nicotine, the nicotine salt of formation is being sucked by suitable proportion
The middle fragrance generated after similar natural baccy burning, so that user is easier to receive the intake of higher concentration nicotine, meanwhile, this
It invents the compound nicotine salt to be easier to enter blood, to be easier to be absorbed by the body to reach the effect for releasing smoking addiction
Fruit, for compound nicotine salt of the present invention closer to the existence of Nicotine in Tobacco, safety in utilization is higher, and fragrance is also more
Close to natural baccy, more commercially available electronics smoke product, which has, more preferably sucks experience.
Specific embodiment
Below by specific embodiment, the invention will be further described.
Embodiment 1
The present embodiment provides a kind of compound nicotine salt, raw material components include: organic acid 500g, nicotine alkali 500g, institute
It is composed of the following components by mass percentage to state organic acid: benzoic acid 20%, linolenic acid 10%, linoleic acid 50%, citric acid
9%, malic acid 10%, ascorbic acid 1%.
Further, a kind of method preparing the compound nicotine salt is provided, includes the following steps: to compare benzene by above-mentioned quality
Formic acid 100g, linolenic acid 50g, linoleic acid 250g, citric acid 45g, malic acid 50g, ascorbic acid 5g are uniformly mixed, and are mixed
Expect S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；Mixture S2 is poured into mixture
In S1, nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to 50 DEG C, heating while stirring makes sufficiently
Reaction, the speed of the stirring be 50rpm to get.
Embodiment 2
The present embodiment provides a kind of compound nicotine salt, raw material components include: organic acid 400g, nicotine alkali 600g, institute
It is composed of the following components by mass percentage to state organic acid: benzoic acid 20%, linolenic acid 10%, linoleic acid 50%, citric acid
9%, malic acid 10%, ascorbic acid 1%.
Further, a kind of method preparing the compound nicotine salt is provided, includes the following steps: to compare benzene by above-mentioned quality
Formic acid 80g, linolenic acid 40g, linoleic acid 200g, citric acid 36g, malic acid 40g, ascorbic acid 4g are uniformly mixed, and are mixed
Expect S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；Mixture S2 is poured into mixture
In S1, nicotine alkali 600g, glycerine and each 250g of propylene glycol is then added, is heated to 50 DEG C, heating while stirring makes sufficiently
Reaction, the speed of the stirring be 50rpm to get.
Embodiment 3
The present embodiment provides a kind of compound nicotine salt, raw material components include: organic acid 600g, nicotine alkali 400g, institute
It is composed of the following components by mass percentage to state organic acid: benzoic acid 20%, linolenic acid 10%, linoleic acid 50%, citric acid
9%, malic acid 10%, ascorbic acid 1%.
Further, a kind of method preparing the compound nicotine salt is provided, includes the following steps: to compare benzene by above-mentioned quality
Formic acid 120g, linolenic acid 60g, linoleic acid 600g, citric acid 54g, malic acid 60g, ascorbic acid 6g are uniformly mixed, and are mixed
Expect S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；Mixture S2 is poured into mixture
In S1, nicotine alkali 400g, glycerine and each 250g of propylene glycol is then added, is heated to 50 DEG C, heating while stirring makes sufficiently
Reaction, the speed of the stirring be 50rpm to get.
Embodiment 4
The present embodiment provides a kind of compound nicotine salt, raw material components include: organic acid 500g, nicotine alkali 500g, institute
It is composed of the following components by mass percentage to state organic acid: benzoic acid 20%, linolenic acid 10%, linoleic acid 50%, citric acid
9%, malic acid 10%, ascorbic acid 1%.
Further, a kind of method preparing the compound nicotine salt is provided, includes the following steps: to compare benzene by above-mentioned quality
Formic acid 100g, linolenic acid 50g, linoleic acid 250g, citric acid 45g, malic acid 50g, ascorbic acid 5g are uniformly mixed, and are mixed
Expect S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；Mixture S2 is poured into mixture
In S1, nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to 70 DEG C, heating while stirring makes sufficiently
Reaction, the speed of the stirring be 70rpm to get.
Embodiment 5
The present embodiment provides a kind of compound nicotine salt, raw material components include: organic acid 500g, nicotine alkali 500g, institute
It is composed of the following components by mass percentage to state organic acid: benzoic acid 20%, linolenic acid 10%, linoleic acid 50%, citric acid
9%, malic acid 10%, ascorbic acid 1%.
Further, a kind of method preparing the compound nicotine salt is provided, includes the following steps: to compare benzene by above-mentioned quality
Formic acid 100g, linolenic acid 50g, linoleic acid 250g, citric acid 45g, malic acid 50g, ascorbic acid 5g are uniformly mixed, and are mixed
Expect S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；Mixture S2 is poured into mixture
In S1, nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to 90 DEG C, heating while stirring makes sufficiently
Reaction, the speed of the stirring be 90rpm to get.
Comparative example 1
Difference with embodiment 5, which is only that, replaces the benzoic acid in organic acid with diluent glycerine and propylene glycol.This
Embodiment provides a kind of compound nicotine salt, and raw material components include: organic acid 500g, nicotine alkali 500g, and the organic acid is pressed
Mass percent is composed of the following components: glycerine and propylene glycol account for 20%, linolenic acid 10%, linoleic acid 50%, citric acid altogether
9%, malic acid 10%, ascorbic acid 1%.The preparation method of the compound nicotine salt, includes the following steps: by above-mentioned quality
, linolenic acid 50g 50g more each than glycerine and propylene glycol, linoleic acid 250g, citric acid 45g, malic acid 50g, ascorbic acid 5g mixing
Uniformly, mixture S1 is obtained；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；By mixture
S2 is poured into mixture S1, and nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to 90 DEG C, Bian Jiare
Side stirring makes sufficiently to react, the speed of the stirring be 90rpm to get.
Comparative example 2
Difference with embodiment 5, which is only that, replaces the linolenic acid in organic acid with diluent glycerine and propylene glycol.This
Embodiment provides a kind of compound nicotine salt, and raw material components include: organic acid 500g, nicotine alkali 500g, and the organic acid is pressed
Mass percent is composed of the following components: benzoic acid 20%, glycerine and propylene glycol account for 10%, linoleic acid 50%, citric acid altogether
9%, malic acid 10%, ascorbic acid 1%.The preparation method of the compound nicotine salt, includes the following steps: by above-mentioned quality
Than benzoic acid 100g, glycerine and propylene glycol is 25g each, linoleic acid 250g, citric acid 45g, malic acid 50g, ascorbic acid 5g are mixed
It closes uniformly, obtains mixture S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；It will mixing
Material S2 is poured into mixture S1, and nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to 90 DEG C, Bian Jia
The stirring of hot side makes sufficiently to react, the speed of the stirring be 90rpm to get.
Comparative example 3
Difference with embodiment 5, which is only that, replaces the linoleic acid in organic acid with diluent glycerine and propylene glycol.This
Embodiment provides a kind of compound nicotine salt, and raw material components include: organic acid 500g, nicotine alkali 500g, and the organic acid is pressed
Mass percent is composed of the following components: benzoic acid 20%, linolenic acid account for 10%, glycerine and propylene glycol and account for 50%, lemon altogether
Sour 9%, malic acid 10%, ascorbic acid 1%.The preparation method of the compound nicotine salt, includes the following steps: by above-mentioned matter
Amount is than benzoic acid 100g, linolenic acid 25g, glycerine and propylene glycol is 125g each, citric acid 45g, malic acid 50g, ascorbic acid 5g
It is uniformly mixed, obtains mixture S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture S2；It will mix
It closes material S2 to pour into mixture S1, nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to 90 DEG C, side
The stirring of heating side makes sufficiently to react, the speed of the stirring be 90rpm to get.
Comparative example 4
Difference with embodiment 5, which is only that, replaces the citric acid in organic acid with diluent glycerine and propylene glycol.This
Embodiment provides a kind of compound nicotine salt, and raw material components include: organic acid 500g, nicotine alkali 500g, and the organic acid is pressed
Mass percent is composed of the following components: benzoic acid 20%, linolenic acid account for 10%, linoleic acid and account for 50%, glycerine and the third two altogether
Alcohol accounts for 9%, malic acid 10%, ascorbic acid 1% altogether.The preparation method of the compound nicotine salt, includes the following steps: by upper
Quality is stated than benzoic acid 100g, linolenic acid 25g, linoleic acid 250g, glycerine and propylene glycol is 22.5g each, malic acid 50g, anti-bad
Hematic acid 5g is uniformly mixed, and obtains mixture S1；250g squalene and 250g saualane are uniformly mixed by 1:1, obtain mixture
S2；Mixture S2 is poured into mixture S1, nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, is heated to
90 DEG C, heating while stirring makes sufficiently to react, the speed of the stirring be 90rpm to get.
Comparative example 5
Difference with embodiment 5, which is only that, replaces the malic acid in organic acid with diluent glycerine and propylene glycol.This
Embodiment provides a kind of compound nicotine salt, and raw material components include: organic acid 500g, nicotine alkali 500g, and the organic acid is pressed
Mass percent is composed of the following components: benzoic acid 20%, linolenic acid account for 10%, linoleic acid and account for 50%, citric acid altogether to be accounted for altogether
9%, glycerine and propylene glycol account for 10%, ascorbic acid 1% altogether.The preparation method of the compound nicotine salt, including walk as follows
It is rapid: by above-mentioned quality than benzoic acid 100g, linolenic acid 25g, linoleic acid 250g, citric acid 45g, glycerine and propylene glycol it is 25g each,
Ascorbic acid 5g is uniformly mixed, and obtains mixture S1；250g squalene and 250g saualane are uniformly mixed by 1:1, mixed
Close material S2；Mixture S2 is poured into mixture S1, nicotine alkali 500g, glycerine and each 250g of propylene glycol is then added, adds
To 90 DEG C, heat while stirring makes sufficiently to react heat, the speed of the stirring be 90rpm to get
Experimental example
It randomly selects 100 smoking personages to suck and give a mark to experience is sucked, collects marking as a result, being shown in Table 1.Selection
Flue gas, jealous, satisfaction and irritation totally four evaluation indexes, wherein jealous and be divided into tobacco flavor, mouthfeel, enter larynx smooth degree
And aftertaste degree, each above-mentioned index full marks are 3 points, the arithmetic mean of instantaneous value for taking 100 people to give a mark.
Flue gas: full -3 points；Moderate -2 points；Slightly it is short of 1 point；It is -0 point insufficient；
Tobacco flavor: strong 3 points；Moderate 2 points；Thin 1 point；No tobacco flavor 0 divides；
Mouthfeel: pure and mild fine and smooth 3 points；Moderate -2 points；More puckery -1 point；Astringent taste is -0 point obvious
Enter larynx smooth degree: smooth -3 points；Smoothly -2 points；Slightly -1 point of impact sense；It has some setbacks -0 point；
Aftertaste degree: -3 points sweet；It is -2 points fresh and sweet；Purer -1 point；Without -0 point of obvious aftertaste
Satisfaction: meet -3 points；Slightly it is short of -2 points；Obvious -1 point of shortcoming；Without -0 point of satisfaction；
Irritation: non-stimulated -3 points；Slightly stimulate -2 points；There is certain -1 point of stimulation；There is -0 point of obvious stimulation.
Table 1 sucks marking result statistics
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of compound nicotine salt, which is characterized in that be made by following raw material: organic acid 40-60 parts by weight, nicotine 40-
60 parts by weight, the organic acid are made of organic acids such as benzoic acid, linolenic acid, linoleic acid, citric acid, malic acid, ascorbic acid.
2. compound nicotine salt according to claim 1, which is characterized in that the organic acid is by mass percentage by following
Group is grouped as: benzoic acid 10-20%, linolenic acid 10-20%, linoleic acid 10-60%, citric acid 5-10%, malic acid 10-
20%, ascorbic acid 1-2%.
3. compound nicotine salt according to claim 2, which is characterized in that the organic acid is by mass percentage by following
Group is grouped as: benzoic acid 20%, linolenic acid 10%, linoleic acid 50%, citric acid 9%, malic acid 10%, ascorbic acid 1%.
4. a kind of solution electronics tobacco tar based on any one of the claim 1-3 compound nicotine salt, which is characterized in that also wrap
Include diluent, the mass ratio of the diluent and the compound nicotine salt is 60-40:40-60.
5. the compound nicotine salt solution of electronic cigarette according to claim 4, which is characterized in that the diluent is the third three
Alcohol, propylene glycol, squalene and saualane, wherein glycerine and propylene glycol are electronic cigarette conventional substrate, and squalene and saualane are
Naturally occurring cured tobacco leaf, burley tobaccos tobacco leaf, Turkish tobaccos tobacco leaf, the volatile oil in flue gas.
6. compound nicotine salt solution electronics tobacco tar according to claim 5, which is characterized in that the glycerine, the third two
The mass ratio of alcohol, squalene and saualane is 1-5:1-5:1-5:1-5.
7. the preparation method of compound nicotine salt described in claim 1, which is characterized in that specific steps are as follows: by benzoic acid, flax
Acid, linoleic acid, citric acid, malic acid, ascorbic acid are uniformly mixed, and obtain mixture S1；Squalene and saualane are uniformly mixed,
Obtain mixture S2；Mixture S2 is poured into mixture S1, nicotine alkali is then added, heating while stirring, it is sufficiently anti-to make
It should be to get.
8. preparation method according to claim 7, which is characterized in that the speed of the stirring is 50-100rpm, described to add
Heat to temperature is 50-90 DEG C.
9. the preparation method of compound nicotine salt solution electronics tobacco tar described in claim 4, which is characterized in that specific steps are as follows:
Benzoic acid, linolenic acid, linoleic acid, citric acid, malic acid, ascorbic acid are uniformly mixed, mixture S1 is obtained；By squalene and
Saualane is uniformly mixed, and obtains mixture S2；Mixture S2 is poured into mixture S1, nicotine alkali, Bian Jiare is then added
Side stirring makes sufficiently to react, and obtains nicotine salt first product, the nicotine salt crude product is diluted to matter with glycerine and propylene glycol
Measure percent concentration be 40-60% to get.
10. application of the described in any item compound nicotine salt solution of claim 4-6 in electronic cigarette.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111000283A (en) * | 2019-12-13 | 2020-04-14 | 武汉红金叶新材料科技有限公司 | Electronic cigarette oil for aerosol device and preparation method and application thereof |
| CN111072631A (en) * | 2019-12-23 | 2020-04-28 | 华宝香精股份有限公司 | Preparation method of colorless benzoic acid nicotine salt |
| CN111466608A (en) * | 2020-04-20 | 2020-07-31 | 铂德（深圳）科技有限公司 | Liquid sea salt nicotine and preparation method thereof |
| CN112715555A (en) * | 2020-12-18 | 2021-04-30 | 湖北和诺生物工程股份有限公司 | Synthetic method and application of nicotine salt |
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| CN113912585A (en) * | 2021-11-09 | 2022-01-11 | 深圳萨特瓦生物科技有限公司 | Composite nicotine salt, preparation method and application thereof, electronic cigarette oil and electronic cigarette |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102161611A (en) * | 2011-03-11 | 2011-08-24 | 中国烟草总公司广东省公司 | Method for preparing squalene based on tobacco as raw material |
| CN107536099A (en) * | 2017-09-14 | 2018-01-05 | 昌宁德康生物科技（深圳）有限公司 | A kind of nicotine salt and preparation method thereof |
| CN108887731A (en) * | 2018-08-21 | 2018-11-27 | 深圳瀚星翔科技有限公司 | Nicotine salt, electronics tobacco tar and preparation method thereof |
| CN109007981A (en) * | 2018-09-10 | 2018-12-18 | 深圳市新宜康科技股份有限公司 | A kind of liquid nicotine salt and preparation method thereof |
| CN109619655A (en) * | 2019-01-18 | 2019-04-16 | 深圳市同信兴投资有限公司 | A kind of compound nicotine salt and its solution, preparation method and application |
| US20190116863A1 (en) * | 2017-10-24 | 2019-04-25 | Rai Strategic Holdings, Inc. | Method for formulating aerosol precursor for aerosol delivery device |
| CN109717505A (en) * | 2019-02-22 | 2019-05-07 | 广东省金叶科技开发有限公司 | A kind of cigarette additive and its application |
-
2019
- 2019-08-27 CN CN201910796592.5A patent/CN110477442A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102161611A (en) * | 2011-03-11 | 2011-08-24 | 中国烟草总公司广东省公司 | Method for preparing squalene based on tobacco as raw material |
| CN107536099A (en) * | 2017-09-14 | 2018-01-05 | 昌宁德康生物科技（深圳）有限公司 | A kind of nicotine salt and preparation method thereof |
| US20190116863A1 (en) * | 2017-10-24 | 2019-04-25 | Rai Strategic Holdings, Inc. | Method for formulating aerosol precursor for aerosol delivery device |
| CN108887731A (en) * | 2018-08-21 | 2018-11-27 | 深圳瀚星翔科技有限公司 | Nicotine salt, electronics tobacco tar and preparation method thereof |
| CN109007981A (en) * | 2018-09-10 | 2018-12-18 | 深圳市新宜康科技股份有限公司 | A kind of liquid nicotine salt and preparation method thereof |
| CN109619655A (en) * | 2019-01-18 | 2019-04-16 | 深圳市同信兴投资有限公司 | A kind of compound nicotine salt and its solution, preparation method and application |
| CN109717505A (en) * | 2019-02-22 | 2019-05-07 | 广东省金叶科技开发有限公司 | A kind of cigarette additive and its application |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111000283A (en) * | 2019-12-13 | 2020-04-14 | 武汉红金叶新材料科技有限公司 | Electronic cigarette oil for aerosol device and preparation method and application thereof |
| CN111072631A (en) * | 2019-12-23 | 2020-04-28 | 华宝香精股份有限公司 | Preparation method of colorless benzoic acid nicotine salt |
| CN111466608A (en) * | 2020-04-20 | 2020-07-31 | 铂德（深圳）科技有限公司 | Liquid sea salt nicotine and preparation method thereof |
| CN111466608B (en) * | 2020-04-20 | 2022-04-12 | 铂德（深圳）科技有限公司 | Liquid sea salt nicotine and preparation method thereof |
| CN112715555A (en) * | 2020-12-18 | 2021-04-30 | 湖北和诺生物工程股份有限公司 | Synthetic method and application of nicotine salt |
| WO2022152529A1 (en) * | 2021-01-12 | 2022-07-21 | Ventus Medical Limited | Aerosolizable nicotine-containing formulations |
| CN112851636A (en) * | 2021-01-20 | 2021-05-28 | 深圳市艾普生物科技有限公司 | Preparation method and application of synthetic nicotine salt |
| CN112841709A (en) * | 2021-01-20 | 2021-05-28 | 深圳市艾普生物科技有限公司 | Preparation method and application of nicotine salt |
| WO2022156268A1 (en) * | 2021-01-20 | 2022-07-28 | 深圳市艾普生物科技有限公司 | Preparation method for and use of synthetic nicotine salt |
| CN113845354A (en) * | 2021-10-18 | 2021-12-28 | 深圳市真味生物科技有限公司 | Preparation method of nicotine salt atomizer with low irritation |
| CN113912585A (en) * | 2021-11-09 | 2022-01-11 | 深圳萨特瓦生物科技有限公司 | Composite nicotine salt, preparation method and application thereof, electronic cigarette oil and electronic cigarette |
| CN113912585B (en) * | 2021-11-09 | 2023-02-24 | 深圳萨特瓦生物科技有限公司 | Composite nicotine salt, preparation method and application thereof, electronic cigarette oil and electronic cigarette |
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