CN113840613A - 具有预防和治疗激素依赖性皮炎功效的生物多糖及其应用 - Google Patents

具有预防和治疗激素依赖性皮炎功效的生物多糖及其应用 Download PDF

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CN113840613A
CN113840613A CN202080035862.1A CN202080035862A CN113840613A CN 113840613 A CN113840613 A CN 113840613A CN 202080035862 A CN202080035862 A CN 202080035862A CN 113840613 A CN113840613 A CN 113840613A
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Prior art keywords
glucan
beta
hormone
dependent dermatitis
skin
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Inventor
郭宏亮
庄秀园
朱斌念
叶榛
吴佳迪
王轩
郭晓宇
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Zhejiang Gllion Bioscience Co ltd
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Zhejiang Gllion Bioscience Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

一种包含β‑葡聚糖的组合物，用于预防和/或治疗激素依赖性皮炎、皮肤去粘膜炎症或其他皮肤炎性疾病。

Description

PCT国内申请，说明书已公开。

Claims (14)

  1. PCT国内申请，权利要求书已公开。
CN202080035862.1A 2019-05-21 2020-05-21 具有预防和治疗激素依赖性皮炎功效的生物多糖及其应用 Pending CN113840613A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019104259817 2019-05-21
CN201910425981.7A CN111973620B (zh) 2019-05-21 2019-05-21 用于预防和治疗激素依赖性皮炎的生物多糖及其应用
PCT/CN2020/091619 WO2020233681A1 (zh) 2019-05-21 2020-05-21 具有预防和治疗激素依赖性皮炎功效的生物多糖及其应用

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CN113840613A true CN113840613A (zh) 2021-12-24

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CN202080035862.1A Pending CN113840613A (zh) 2019-05-21 2020-05-21 具有预防和治疗激素依赖性皮炎功效的生物多糖及其应用

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US (1) US20220241319A1 (zh)
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Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
CN112826977B (zh) * 2020-12-31 2022-09-27 山东纳美德生物科技有限公司 一种液体敷料、皮肤外用组合物及其制备方法及应用
CN113244162B (zh) * 2021-05-24 2022-08-02 杭州荔枝红生物科技有限公司 一种可溶性微针及其制备方法和在制备调节皮肤微生态产品中的应用
CN115634169A (zh) * 2022-04-27 2023-01-24 广州市万千粉丝化妆品有限公司 一种细胞外基质β-肌聚糖蛋白在修复激素依赖皮肤的化妆品中的应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990076537A (ko) * 1998-03-24 1999-10-15 서경배 "치마버섯 유래의 베타-1, 6-분지-베타-1, 3-글루칸의 제조방법및 이 방법에 의해 제조된 베타-1, 6-분지-베타-1, 3-글루칸을함유하는 외용제 조성물
US20080160043A1 (en) * 2007-07-16 2008-07-03 Kim Moo-Sung Preparation method of beta-glucan from schizophyllum commune and composition for external application comprising the same
CN102600494A (zh) * 2012-03-30 2012-07-25 武汉华纳联合药业有限公司 一种多糖组合物及其制备方法和用途
CN106075399A (zh) * 2016-07-22 2016-11-09 简婷婷 用于激素性皮炎的组合物，制剂及制备方法和应用
CN106075120A (zh) * 2016-07-01 2016-11-09 宁波希诺亚海洋生物科技有限公司 一种湿疹乳膏剂
CN110769836A (zh) * 2018-05-23 2020-02-07 浙江立恩生物科技有限公司 预防和治疗痤疮和激素依赖性皮炎的生物多糖及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6261999A (en) * 1998-09-25 2000-04-17 Collaborative Group, Ltd., The Very high molecular weight beta-glucans
WO2007001904A2 (en) * 2005-06-21 2007-01-04 The Procter & Gamble Company Personal care compositions comprising alpha-glucans and/or beta-glucans
CN103981201A (zh) * 2014-05-30 2014-08-13 武汉大学 一种β-葡聚糖基因载体及其制备方法和应用

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990076537A (ko) * 1998-03-24 1999-10-15 서경배 "치마버섯 유래의 베타-1, 6-분지-베타-1, 3-글루칸의 제조방법및 이 방법에 의해 제조된 베타-1, 6-분지-베타-1, 3-글루칸을함유하는 외용제 조성물
US20080160043A1 (en) * 2007-07-16 2008-07-03 Kim Moo-Sung Preparation method of beta-glucan from schizophyllum commune and composition for external application comprising the same
CN102600494A (zh) * 2012-03-30 2012-07-25 武汉华纳联合药业有限公司 一种多糖组合物及其制备方法和用途
CN106075120A (zh) * 2016-07-01 2016-11-09 宁波希诺亚海洋生物科技有限公司 一种湿疹乳膏剂
CN106075399A (zh) * 2016-07-22 2016-11-09 简婷婷 用于激素性皮炎的组合物，制剂及制备方法和应用
CN110769836A (zh) * 2018-05-23 2020-02-07 浙江立恩生物科技有限公司 预防和治疗痤疮和激素依赖性皮炎的生物多糖及其应用
CN110769836B (zh) * 2018-05-23 2022-12-23 浙江立恩生物科技有限公司 预防和治疗痤疮和激素依赖性皮炎的生物多糖及其应用

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CN111973620A (zh) 2020-11-24
CN111973620B (zh) 2024-04-16
US20220241319A1 (en) 2022-08-04

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