CN113631134A - Mixing auxiliary tool for syringe - Google Patents
Mixing auxiliary tool for syringe Download PDFInfo
- Publication number
- CN113631134A CN113631134A CN202080025903.9A CN202080025903A CN113631134A CN 113631134 A CN113631134 A CN 113631134A CN 202080025903 A CN202080025903 A CN 202080025903A CN 113631134 A CN113631134 A CN 113631134A
- Authority
- CN
- China
- Prior art keywords
- syringe
- engagement
- needle
- housing
- holder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 claims abstract description 57
- 238000003825 pressing Methods 0.000 claims abstract description 42
- 238000004891 communication Methods 0.000 claims abstract description 7
- 238000007789 sealing Methods 0.000 claims description 29
- 238000003780 insertion Methods 0.000 claims description 22
- 230000037431 insertion Effects 0.000 claims description 22
- 210000000078 claw Anatomy 0.000 description 25
- 239000003814 drug Substances 0.000 description 22
- 230000002093 peripheral effect Effects 0.000 description 19
- MOVRNJGDXREIBM-UHFFFAOYSA-N aid-1 Chemical compound O=C1NC(=O)C(C)=CN1C1OC(COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)COP(O)(=O)OC2C(OC(C2)N2C3=C(C(NC(N)=N3)=O)N=C2)CO)C(O)C1 MOVRNJGDXREIBM-UHFFFAOYSA-N 0.000 description 11
- 239000007788 liquid Substances 0.000 description 11
- 238000002347 injection Methods 0.000 description 8
- 239000007924 injection Substances 0.000 description 8
- 229940079593 drug Drugs 0.000 description 7
- 230000004308 accommodation Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- -1 butyl halide Chemical class 0.000 description 1
- 229920005549 butyl rubber Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000005060 rubber Substances 0.000 description 1
- 239000003566 sealing material Substances 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 238000009751 slip forming Methods 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 229920002725 thermoplastic elastomer Polymers 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a mixing auxiliary tool, comprising: a housing in which a sealed container filled with a first substance for mixing is provided; a holder for fixing a syringe in which a plunger is disposed and a second substance for mixing is filled; the shell and the bracket are arranged along a puncturing direction for puncturing the sealed container by a needle which enables the syringe and the sealed container to be communicated, and the shell and the bracket are relatively slidably moved to a position where the sealed container is communicated with the syringe by the needle; an operation member including a slide engagement portion and a press engagement portion; a slide engaging portion that is capable of sliding the holder to the communication position with respect to the housing in an engaged state in which at least one of the holder and the syringe is engaged with an engagement target; a pressing engagement portion capable of pressing the plunger toward the sealed container when the plunger of the syringe provided at the communication position is in an engaged state; a switching structure is provided between the engagement object and the operation member, and the switching structure releases the engagement state between the slide engagement portion and the engagement object by applying a pressing force to the operation member in the puncturing direction, and switches to engagement between the pressing engagement portion and the plunger.
Description
Technical Field
The present invention relates to an aid for mixing a substance in a sealed container with a substance in a syringe at the time of injection.
Background
Conventionally, various products have been proposed as a mixing aid (hereinafter referred to as an aid) for a syringe, for example, the aid (an aid for preparing a drug solution) disclosed in patent document 1, which is a tubular body used as a syringe, and includes a tubular body (hereinafter referred to as a first needle unit) in which a drug storage case filled with a drug solution is disposed, an inner cylindrical support for fixing the drug solution in the storage case and a tubular bottle containing another drug solution, a tubular body (hereinafter referred to as a second needle unit) accommodating the inner cylindrical support and fitted to the first needle unit, and two needles disposed between the drug storage case and the tubular bottle. The first and second needle cannula parts are slidable relative to each other in a state in which the respective axial directions are kept coincident.
The vial and the inner cylindrical support are both cylindrical. The opening on the top end side of the vial is closed with a metal cap, and the opening on the rear end side of the vial is opened. The opening on the front end side and the opening on the rear end side of the inner cylindrical support are all in an open state.
A through hole penetrating the inside and outside is provided in the diameter direction of the inner tubular support, and the through hole is an inlet and outlet hole of the projecting portion of the elastic rod described later on the second needle tube portion.
The second needle tube section is provided with an elastic rod for restricting sliding relative to the inner support. The syringe is composed of an elastic rod elastically deformable in the diameter direction and a cylindrical push rod (generally, a plunger) for pushing out the liquid medicine in the vial.
The elastic rod extends in the axial direction of the second pipe portion. The elastic rod includes an inclined surface inclined radially inward from the front end side to the rear end side of the second needle tube part, and a protruding portion located on the rear end side of the second needle tube part and protruding radially inward of the second needle tube part.
The elastic rod can be inserted into the through hole of the inner cylindrical support with its protruding portion in a state of being undeformed in the diameter direction of the second needle tube portion.
The cylindrical push rod extends from the rear end to the front end side in the second needle tube part, and is inserted into the tubular bottle through the opening at the rear end side of the inner cylindrical support and the opening at the rear end side of the tubular bottle.
The two-headed needle is mounted between the medicine storage box and the tubular bottle in a state in which the central line extending direction thereof is aligned with the axis extending directions of the first needle tube part and the second needle tube part. Thus, the two-headed needle has one end facing the medicine storage case and the other end facing the vial.
According to the auxiliary tool with the structure, the first needle tube part and the second needle tube part slide relatively to shorten the distance between the medicine storage box and the tubular bottle, the end part of one side of the two-head needle is inserted into the medicine storage box, the end part of the other side of the two-head needle is inserted into the tubular bottle, and the inside of the medicine storage box and the inside of the tubular bottle are communicated together through the intervention of the two-head needle.
When the first needle tube part and the second needle tube part continue to slide, the inclined surface contacts with the opening end of the inner side of the first needle tube part. Therefore, the inclined surface is pressed radially outward of the second needle pipe portion, and the inclined lever is bent radially outward of this.
At the same time, the second needle unit can slide toward the inner cylindrical support because the protruding portion is offset from the through hole of the inner cylindrical support.
The second needle cannula continues to slide toward the inner tubular support, causing the cylindrical plunger to advance within the vial, pushing the contents of the vial into the drug storage cartridge.
Documents of the prior art
Patent document
Patent document 1, patent No. 4455888
Disclosure of Invention
Problems to be solved by the invention
In the above-described assisting tool, when the plunger advances in the vial, the first needle section pushes the elastic rod, in other words, the elastic rod is in a state of being pushed by the first needle section, and the pushing force of the elastic rod with respect to the first needle section becomes a load when the second needle section and the first needle section slide relative to each other.
Therefore, in the above-described assisting tool, the movement of the second needle cannula portion to the first needle cannula portion is difficult, and the movement of the plunger is also difficult.
Therefore, the above-described assisting tool is a device that requires a plunger pushing operation and another operation, and increases the load on the plunger pushing operation, thereby deteriorating the operability of the plunger.
Accordingly, an object of the present invention is to provide a mixing aid for a syringe that allows a plunger to be pushed in more smoothly.
Means for solving the problems
The invention relates to a mixing aid, comprising:
a housing in which a sealed container filled with a first substance for mixing is provided;
a holder for fixing a syringe in which a plunger is disposed and a second substance for mixing is filled;
the shell and the bracket are arranged along a puncturing direction for puncturing the sealed container by a needle which enables the syringe and the sealed container to be communicated, and the shell and the bracket are relatively slidably moved to a position where the sealed container is communicated with the syringe by the needle;
an operation member including a slide engagement portion and a press engagement portion; wherein,
a slide engaging portion that is capable of sliding the holder to the communication position with respect to the housing in an engaged state in which at least one of the holder and the syringe is engaged with an engagement target;
a pressing engagement portion that can press the plunger toward the sealed container when the plunger of the syringe provided at the communication position is in an engaged state;
a switching structure is provided between the engagement object and the operation member, and the switching structure releases the engagement state between the slide engagement portion and the engagement object by applying a pressing force to the operation member in the puncturing direction, and switches to engagement between the pressing engagement portion and the plunger.
According to the above-described mixing aid, when the first substance in the sealed container is moved to the syringe, the slide engaging portion is engaged with at least one of the holder and the syringe by pressing the operating member, the holder is moved toward the housing, the needle pierces the sealed container, and the sealed container and the syringe are brought into communication with each other through the needle.
With the switching structure, the force used in the pushing operation releases the engagement state between the slide engagement portion and at least one of the holder and the syringe, and the pushing engagement portion and the plunger are engaged with each other, thereby reducing the force required for pushing the plunger.
The mixing aid can reduce the load on the operating member during the plunger press-in operation, and the press-in of the plunger becomes smoother.
The switching structure causes the holder to rotate in a circumferential direction with respect to the operating member about a virtual line extending in the puncture direction by applying a pressing force in the puncture direction to the operating member, thereby releasing the engagement state between the slide engagement portion and the engagement object.
According to the above configuration, when the operation member is operated, the engagement state of the slide engagement portion and at least one of the holder and the syringe can be released only by completing the rotation of the holder, and the operability is improved.
In the mixing aid of the present invention, the housing and the operating member are both of a cylindrical structure, and the holder can be inserted in the axial direction thereof; the operating component is sleeved outside the shell, and an accommodating space capable of accommodating the bracket is formed between the operating component and the shell, so that the bracket fixed with the injector is arranged between the shell and the operating component; the accommodating space is in a sealed state and is provided with a sealing lock for limiting relative movement between the shell and the operating member.
According to the above-described mixing aid, for example, the syringe and the holder after injection use are placed in the housing space, and because the housing space is sealed and the relative movement between the housing and the operating member is restricted due to the seal lock structure, the exposure of the first and second substances and the mixed medicament can be prevented.
In the mixing aid according to the present invention, a holding structure capable of fixing the operation member in the housing is provided at a position where the pressing engagement portion pushes the plunger toward the sealed container.
According to the holding structure, the operating member and the housing can be held and fixed at the position where the plunger is pushed into the sealed container, and the operating member and the housing are not easily separated from each other. Therefore, for example, in the case where the second substance in the syringe is a liquid, when the second substance is injected into the sealed container, the operation member and the housing are held by hand and shaken, and the first substance and the second substance are mixed more easily.
In the mixing aid of the present invention, the needle is provided at the tip of the syringe, the holder is provided with a cylindrical insertion inlet portion for fixing the syringe, and the syringe is inserted into the insertion inlet portion from the needle side; the insertion opening has an outer inner diameter larger than an inner diameter of the insertion opening in the insertion direction of the syringe.
According to the above structure, when the syringe is inserted into the insertion inlet part from the needle, the needle is difficult to contact with the insertion inlet part, and the bending and the breakage of the needle can be prevented.
Effects of the invention
As described above, the mixing tool of the present invention can achieve an excellent effect of smoothly pressing the plug.
Drawings
FIG. 1 is an external view of a mixing aid in an embodiment;
FIG. 2 is an exploded perspective view of the mixing aid in accordance with the present embodiment;
FIG. 3 is a front view of a housing of the mixing aid in accordance with an embodiment;
FIG. 4 is a plan view of the housing of the mixing aid in accordance with the present embodiments;
FIG. 5 is a cross-sectional view taken along line V-V of FIG. 4;
FIG. 6 is a plan view of a hybrid aid in accordance with an embodiment of the present invention;
FIG. 7 is a side view of a hybrid aid in accordance with an embodiment of the present invention;
FIG. 8 is a plan view of an operating member of the mixing aid in the same embodiment;
FIG. 9 is an oblique cross-sectional view taken along line IX-IX of FIG. 8;
FIG. 10 is a longitudinal sectional view of the syringe in the same embodiment;
FIG. 11 is a plan view of the syringe in the same embodiment;
FIG. 12 is a longitudinal sectional view of the sealed container in the same embodiment;
FIG. 13 is a longitudinal cross-sectional view of the hybrid aid prior to use in accordance with the present embodiment;
FIG. 14 is a view showing the mixing aid in the state of use in which it is used in the same embodiment, i.e., a view showing the needle of the syringe piercing the sealed container;
FIG. 15 is an explanatory view of the mixing aid in the same embodiment in a use state, i.e., in a state where the plunger is pressed in;
fig. 16 is an explanatory view of the mixing assist tool in a state of use in the same embodiment, that is, in a state where the housing space is sealed and the housing and the operating member are locked;
FIG. 17 is an enlarged view of the mixing tool in the same manner as in the first embodiment, showing the periphery of the operation member when the operation member is initially pushed into the housing;
FIG. 18 is an enlarged view of the mixing aid in the same embodiment in the use state, i.e., the periphery of the operating member in the state where the needle of the syringe pierces the sealed container;
FIG. 19 is an enlarged view of the mixing aid in the same embodiment in the use state, i.e., the periphery of the operating member in the rotating state of the syringe and the holder;
FIG. 20 is an enlarged view of the mixing aid in the same embodiment in the use state, i.e., the periphery of the operating member in the state where the plunger is pressed in after the syringe and the holder are rotated;
fig. 21 is an enlarged view of the mixing tool in the same embodiment in the use state, that is, an enlarged view of the periphery of the operation member in the plunger press-in released state;
FIG. 22 is an enlarged longitudinal cross-sectional view of a portion of a mixing aid for syringes with caps in accordance with other embodiments of the present invention;
FIG. 23 is an enlarged longitudinal cross-sectional view of a portion of a mixing aid for syringes with caps in accordance with another embodiment of the present invention;
FIG. 24 is a front view of a needle unit of a mixing aid for a syringe according to another embodiment of the invention;
FIG. 25 is a longitudinal cross-sectional view of the needle unit of FIG. 24;
FIG. 26 is an explanatory view of the mixing aid after mounting the needle unit shown in FIG. 24, and is an explanatory view of a state before use;
FIG. 27 is an enlarged view of FIG. 26;
FIG. 28 is an explanatory view of a state in which the needle unit shown in FIG. 26 is used, that is, a state in which the tip end of the needle head is inserted into the sealing cap of the sealed container (vial);
fig. 29 is an explanatory view of the needle unit shown in fig. 26 in a state of use, that is, in a state where the needlepoint on the proximal end side of the needle penetrates the seal ring portion of the syringe.
Detailed Description
The mixing aid for syringe (hereinafter referred to as mixing aid) of the present invention will be described below with reference to the accessories.
As shown in fig. 1, the mixing aid 1 includes a housing 2, a sealed container 6 provided in the housing 2 and filled with a first substance for mixing, a holder 3 (see fig. 2) that can be inserted into the housing 2 and can fix a syringe, and an operating member 4 fitted around the outside of the housing 2. Fig. 2 also shows a portion of the syringe 5 for clarity of illustration. As shown in fig. 13 and 14, the housing 2 and the holder 3 are provided in such a manner that the needle 52 of the syringe 5 faces the direction for piercing the sealed container 6, and can be engaged with each other by sliding in the piercing direction of the needle 52, so that the sealed container 6 communicates with the syringe 5. In the present embodiment, the direction in which the housing 2 and the bracket 3 slide relative to each other is referred to as the front-rear direction. In addition, a film-like fixing member S (see fig. 1) is provided at a joint between the case 2 and the operation member 4 in order to fix the case 2 and the operation member 4.
As shown in fig. 10, the syringe 5 includes: a syringe body 50 filled with a second substance for mixing, a plunger 51 for pushing out the second substance, a needle (injection needle) 52 provided directly or indirectly at a nozzle of the syringe body 50, and a needle sheath 53 covering the outside of the injection needle 52. A finger grip 54 is mounted at the flange of the syringe body 50. The sleeve 53 is resilient so that it can be pierced by the needle 52. As shown in FIG. 11, finger grip 54 has a transverse width W1 that is greater than a longitudinal width W2 in plan view. The finger clip 54 extends in opposite directions (i.e., opposite to the radial direction of the syringe body 50) from the syringe body 50 at one end side and the other end side in the longitudinal direction when it is attached to the syringe body 50.
In the syringe 5 according to the present embodiment, as shown in fig. 10, the needle 52 is indirectly provided on the nozzle 500; specifically, a tubular needle base 520 is fitted around the end of the nozzle 500, and the needle 52 is mounted on the front end of the needle base 520. Based on this, needle base 520 and needle 52 constitute a disposable needle. Of course, needle 52 may be disposed directly on nozzle 500.
The needle cap 53 is made of an elastic material. For example: butyl rubber, butyl halide rubber, styrene-butadiene rubber, synthetic natural rubber, silicone rubber, thermoplastic elastomer, and the like. In this embodiment, the needle cap 53 has a cylindrical portion 530, the bottom end of which is fitted over the outside of the needle base 520; the front end of the cylindrical portion 530 is connected to a seal portion 531 which can be pierced by the needle 52.
The seal portion 531 is fitted into the cylindrical portion 530 so as to be axially movable in the cylindrical portion 530. When the sealing part 531 is in contact with another part, the syringe body 50 is moved, and the syringe body 50 and the cylindrical part 530 move synchronously toward the sealing part 531, and the needle 52 moves forward and reaches the tip of the sealing part 531.
The sealed container 6, a so-called vial, includes a container body 60 filled with a first substance, and a sealing plug 61 for closing an inlet and an outlet of the container body 60, as shown in fig. 12. The outer peripheral portion 61a of the sealing plug 61 has an outer diameter larger than that of the neck portion 60a of the container body 60 and protrudes outward in a flange shape.
At least one of the syringe body 50 and the container body 60 is filled with a liquid substance. That is, in the syringe body 50 and the container body 60, one of them is filled with a liquid substance and the other is filled with a liquid or powdery substance.
As shown in fig. 3 to 5, the housing 2 has a cylindrical shape, and includes a housing main body 20, the housing main body 20 having a cylindrical structure with a bottom surface and being capable of accommodating the sealed container 6; a positioning portion 21 (see fig. 4) for fixing the position of the sealed container 6 is provided in the housing main body portion 20, a holder guide portion 22 (see fig. 4) for guiding the holder 3 is provided in the housing main body portion 20 along the axial direction thereof, an operation member guide portion 23 (see fig. 4) for guiding the operation member 4 is provided in the housing main body portion 20 along the axial direction thereof, and a close-fitting portion 24 for making close contact with the inside of the operation member 4 is formed on the outside of the housing main body portion 20.
The axial direction of the housing body portion 20 is also the axial direction of the housing 2. The direction of the needle 52 of the syringe 5 towards the piercing of the sealed container 6 is also the axial direction of the housing body part 20. The bottom surface of the housing main body portion 20 is disposed in the front-rear direction, which may be the front side of the housing 2, and the opening side of the housing main body portion 20 is disposed in the front-rear direction, which may be the rear side of the housing 2.
The positioning portion 21 is provided inside the housing body portion 20, which can perform radial positioning of the hermetic container 6 inside the housing body portion 20.
More specifically, the positioning portion 21 is provided in plural (3 in the present embodiment) on the bottom surface of the housing main body portion 20, and the plural positioning portions 21 are arranged at intervals in the circumferential direction on the bottom surface of the main body portion.
As shown in fig. 4 and 5, each positioning portion 21 is composed of a bottom receiving portion 210 formed to extend inward in the radial direction of the housing main body portion 20 from the inner peripheral surface of the bottom surface, and a lateral stopper portion 211 formed to extend upward in the axial direction of the housing main body portion 20 from the outer end of the bottom receiving portion 210. The sealed container 6 is mounted on each bottom receiving portion 210, and the lateral stopper portion 211 is interposed between the sealed container 6 and the housing body portion 20.
The holder guide portion 22 is a pair of guide grooves 220 formed on the inner peripheral surface of the housing main body portion 20. The pair of guide grooves 220 are formed to extend from the open end of the housing main body portion 20 to the bottom surface thereof, and the pair of guide grooves 220 are formed to extend along the axial direction of the housing main body portion 20 and are arranged in parallel to each other at intervals in the inner circumferential direction of the housing main body portion 20. Further, a protruding portion 221 that protrudes from the bottom surface of the guide groove 220 toward the inside of the housing main body portion 20 (toward the inside in the radial direction of the housing main body portion 20) is formed between the pair of guide grooves 220.
In this embodiment, the housing body 20 is provided with two sets of bracket guides formed by a pair of guide grooves 220 and a protrusion 221. One set of holder guide portions 22 and the other set of holder guide portions 22 are respectively provided at symmetrical positions in the center (radial center) of the housing main body portion 20.
Of each pair of guide grooves 220, one is a first guide groove 220a for inserting the holder 3 into the housing body portion 20 before the mixing of the substances, and the other is a second guide groove 220b for holding the holder 3 inserted into the housing body portion 20 in an angular rotational position with respect to the housing body portion 20 after the mixing of the substances is completed. The first guide groove 220a and the second guide groove 220b are formed at positions (center positions) that are offset by 45 degrees or about 45 degrees in the circumferential direction around the center axis of the housing 2. In addition, the second guide groove 220b has a longer length than the first guide groove 220a.
As shown in fig. 3 and 4, the operating member guide portion 23 is protrudingly provided outside the housing main body portion 20 (more specifically, outside the open end of the housing main body portion 20). The operation member guide portions 23 are provided in pairs at symmetrical positions with respect to the radial center of the housing main body portion 20. The inner side of one of the operation member guide portions 23 corresponds to the first guide groove 220a of one set of the holder guide portions 22, and the inner side of the other operation member guide portion 23 corresponds to the first guide groove 220a of the other set of the holder guide portions 22.
The sealing portion 24 is in close contact with the inside of the operating member 4 (the inner peripheral surface of the open end of the operating member 4), thereby forming a sealing structure that seals the gap between the housing 2 and the operating member 4.
The close-contact portion 24 according to the present embodiment is formed continuously around the entire circumference in the circumferential direction of the housing main body portion 20, and is composed of a tapered ring portion 240 that gradually protrudes outward (radially outward of the housing main body portion 20) from the rear end to the front end of the housing main body portion 20, and a front side ring 241 that is connected to the front end of the tapered ring portion 240. The height of the front ring 241 (the amount of projection from the surface of the housing main body 20) is constant over the entire circumference, and the width of the front ring 241 (the width in the front-rear direction) is also constant over the entire circumference. The height (the amount of projection in the radial direction from the surface of the housing main body portion 20) of the front end portion (the end portion connected to the front side ring 241) of the tapered ring portion 240 is set to coincide with the height of the front side ring 241.
As shown in fig. 6 and 7, the holder 3 includes a housing portion 30 having a cylindrical structure and into which the syringe 5 is inserted and removed, a stopper portion 31 for preventing the syringe 5 inserted into the housing portion 30 from coming off, an extension portion 32 formed to extend from a front end of the housing portion 30 (a front end corresponding to the injection agent 5 insertion direction), and a container fixing portion 33 provided at a front end of the extension portion 32 and capable of fixing the sealed container 6.
The holder 3 is inserted into the housing 2 from the container fixing portion 33 side, and is rotatable in the circumferential direction around the center line of the housing 2 in the inserted state.
The storage portion 30 is a cylindrical body as described above, and has an insertion opening O at the rear end thereof into which the syringe 5 can be inserted. The inner diameter of the receiving portion 30 on the distal end side is constant or substantially constant, and the inner diameter of the insertion opening O gradually increases (i.e., tapers) from the front (near the back) to the rear (near the proximal opening).
The retaining portion 31 is formed of a pair of walls 310 provided vertically at the rear end of the housing portion 30. The walls 310 are disposed to face each other in the radial direction of the housing portion 30. Therefore, a space is formed adjacent to each wall portion 310.
Each wall portion 310 is composed of an upright portion 311 formed to extend vertically in the axial direction of the housing portion 30, and an extension portion 312 connected to the front end portion (the end portion located on the rear end side in the front-rear direction) of the upright portion 311 and formed to extend toward the other wall portion 310 side in the circumferential direction of the housing portion 30;
the cross-sectional shape of the standing portion 311 and the extending portion 312, which is orthogonal to each other in the axial direction of the accommodating portion 30, is an arc plate shape. The extension 312 has a longer circumferential length than the standing portion 311. Therefore, the space is wider on the front side than on the rear side as compared with the front-rear direction.
In addition, when the syringe 5 is inserted into the holder 3 from the insertion inlet portion O, the two rectangular ends of the finger grips 54 are also fitted in the above-mentioned space, completing the fitting between the syringe 5 and the holder 3. Based on this structural design, the rotation of the finger grip 54 is limited to the above-described spatial range. Further, in a state where finger grip 54 is in contact with one end of upright portion 311, finger grip 54 is also in contact with extension portion 312, and syringe 5 is fixed to holder 3 so as to be prevented from falling off.
The extension portion 32 includes a pair of long plate portions 320 extending in the axial direction of the housing portion 30 and facing each other, and a plurality of connection plates 321 connected to the pair of long plate portions 320. Although no reference numeral is given to each drawing, a through hole through which the syringe 5 can be inserted is provided on the upper surface of the connection plate 321.
The cross-sectional shape of the long plate portion 320 in the direction orthogonal to the axial direction of the housing portion 30 is an arc. The plane view of the connection plate 321 is a circular plate. In this embodiment, three connection plates 321 are arranged at intervals in the axial direction of the accommodating portion 30, and the size of the through hole in the connection plate 321 positioned at the rearmost end is larger than the size of the through holes in the other two connection plates 321.
The long plate portion 320 is provided with a movable claw 322 that can move inside and outside the long plate portion 320. The movable claw 322 is located forward of the wall portion 310 in the aforementioned front-rear direction. Therefore, the movable claw 322 is mounted at a position deviated from the space of the wall portion 310 as viewed from the rear end side of the bracket 3.
The movable claw 322 is constituted by a bendable portion 322a extending in the longitudinal direction of the long plate portion 320 and formed to be bendable, and a protruding claw portion 322b protruding outward from the outer surface of the bendable portion 322a. The bendable portion 322a is formed in an arm shape with its distal end side as a fulcrum and the distal end side is bent inward and outward, and a protruding claw portion 322b is provided at the distal end of the bendable portion 322a.
The container fixing portion 33 includes a plurality of bendable lever portions 330 formed to extend from the front end of the long plate portion 320, inner claw portions 331 formed to protrude inward from the inner surfaces of the front ends of the bendable lever portions 330, and protruding portions 332 formed to protrude inward from the inner surfaces of the bendable lever portions 330 behind the inner claw portions 331. In this embodiment, the long plate portions 320 are connected to the bendable lever portions 330 one by one, the inner claws 331 of the bendable lever portions 330 are symmetrically distributed, and the protrusions 332 are symmetrically disposed on the bendable lever portions 330.
The bendable lever portion 330 is a plate body, and a cross-sectional view thereof taken in a direction orthogonal to the longitudinal direction is an arc shape. A pair of symmetrically arranged bendable lever portions 330 are formed extending from the long plate portion 320 so that the distance between the lever portions becomes shorter as the lever portions approach the front ends.
Similarly, the cross-sectional patterns of the inner claw 331 and the protruding portion 332 in the direction orthogonal to the longitudinal direction are arc-shaped. In the container holder 33, the inner surface of the flexible lever portion 330 and the inner pawl 331 projecting inward from the inner surface are continuous in a step-like manner, and the inner surface of the flexible lever portion 330 and the projection 332 projecting inward from the inner surface are also continuous in a step-like manner. Thus, a recess 333 is formed in the inner surface of the bendable lever portion 330.
As shown in fig. 2, the operating member 4 has a tubular shape, and one open end thereof is closed and the other open end thereof is opened. When the operating member 4 is fitted around the outside of the housing 2, an accommodating space for accommodating the holder 3 is formed between the housing 2 and the operating member 4.
As shown in fig. 8 and 9, the operating member 4 includes: the guided portion 40 that guides the operation member 4 itself to the operation member guide portion 23, the slide engaging portion 41 that slides the holder 3 to the communicating position with respect to the housing 2 in an engaged state with at least one of the holder 3 and the syringe 5 being an engagement target (specifically, the finger clip 54 of the syringe 5 in the present embodiment), the engagement pressing portion 42 that presses the plunger 51 into the sealed container 6 in an engaged state with the plunger 51 of the syringe 5, the abutting portion 43 that abuts against at least one of the syringe 5 and the holder 3 (specifically, the finger clip 54 of the syringe 5 in the present embodiment) in the aforementioned piercing direction after the plunger 51 of the syringe 5 is pressed in, and the step portion 44 formed on the inner peripheral surface of the other end portion.
The guided portion 40 is a groove that is opened in the axial direction in the inner peripheral surface of the operating member 4. As shown in fig. 9, the guided portion 40 includes two parts, a first guided portion 400 that is fitted to the operation member guide portion 23 before the mixing of the substances, and a second guided portion 401 that is fitted to the operation member guide portion 23 after the mixing of the substances is completed. The guided portion 40 (i.e., the first guided portion 400 and the second guided portion 401) is provided at a position rotationally symmetrical by 180 degrees around the axial direction of the operating member 4.
The first guided portion 400 is provided at a position offset in the axial direction from the switching structure described in paragraph 0076 described later (an offset position located forward of the slide engagement portion 41 in the front-rear direction), and the second guided portion 401 is provided at a position aligned in the axial direction with the switching structure described in paragraph 0076 described later (a position located forward of the slide engagement portion 41 in the front-rear direction). The center position of the first guided portion 400 and the center position of the slide engagement portion 41 are both offset by 90 degrees or about 90 degrees in the circumferential direction around the center axis of the operating member 4.
When the operating member guide portion 23 is fitted into the first guided portion 400 in a state where the movable claws 322 of the holder 3 are fitted into the first guide grooves 220a, the slide engaging portion 41 (see fig. 2) is provided behind the object of engagement (finger clip 54) in the front-rear direction.
When the movable claws 322 of the holder 3 are fitted into the second guide grooves 220b in a state where the first guided portion 400 and the operating member guide portion 23 are fitted to each other, the abutting portion 43 is provided behind the engagement object (finger clip 54).
When the operating member guide portion 23 is fitted into the second guided portion 401 in a state where the movable claws 322 of the holder 3 are fitted into the second guide grooves 220b, the engagement pressing portion 42 is provided behind the engagement object. That is, the engagement object (finger clip 54) is provided at a position deviated from the slide engagement portion 41 and the contact portion 43.
The slide engaging portions 41 are formed in a fan-shaped arch structure having a certain thickness and resembling a rectangle that is formed to protrude inward from the inner peripheral surface of the operation member 4 in the radial direction of the operation member 4, and are provided in pairs at symmetrical positions rotated 180 degrees in the axial direction around the operation member 4. As described above (see fig. 2), the slide engaging portion 41 is provided behind the finger grip 54 to be engaged in a state where the movable claw 322 of the holder 3 is fitted in the first guide groove 220a and the first guided portion 400 is fitted in the operating member guide portion 23, and is configured to push the operating member 4 to slide toward the housing 2 and push the finger grip 54 to advance the syringe 5 and the holder 3 in the puncturing direction.
The slide engaging portion 41 includes an end portion on the opposite side to the inner bottom surface 42 of the operation member 4 and an opposing surface 410 disposed to face the syringe 5 and into which the finger grip 54 is pushed. The facing surface 410 is inclined toward the rear side in the front-rear direction (toward the inner bottom surface 42 of the operation member 4) when going from one end side to the other end side in the circumferential direction of the operation member 4.
The engaging and pressing portion 42 is provided on the inner bottom surface of the operation member 4. Therefore, in the operation member 4, the slide engagement portion 41 is positioned in front of the engagement pressing portion 42.
The abutting portions 43 are formed adjacent to the slide engaging portion 41 in the circumferential direction, have a fan arch-like structure having a thickness equal to that of the slide engaging portion 41 and a rectangular shape protruding inward in the radial direction from the inner peripheral surface of the operating member 4, and are provided in pairs at symmetrical positions rotated 180 degrees in the axial direction around the operating member 4. . The contact portion 43 includes a contact surface 430 formed at an end opposite to the inner bottom surface 42 (engaging and pressing portion 42) of the operation member 4. The abutment surface 430 is provided at an intermediate position between the inner bottom surface 42 (the engagement pressing portion 42) of the operation member 4 and the facing surface 410 of the slide engagement portion 41. The slide engagement portion 41 and the abutment portion 430 are located at approximately 45-degree rotational symmetry positions with respect to each other in the axial direction around the operating member 4 at the center thereof in the circumferential direction.
When the syringe 5 and the holder 3 are rotated with respect to the operation member 4, the mixing aid 1 is switched between a state in which the engagement target faces the slide engagement portion 41 and a state in which the engagement target faces the contact portion 43 in the front-rear direction.
In the present embodiment, the operating member 4 is provided with a switching structure for engaging the pressing portion 42 and the plunger 51. The holder 3 is rotated relative to the housing 2 and the operation member 4 by the pressing force received by the operation member 4 in the puncturing direction, so that the engagement state between the slide engaging portion 41 and the engagement object is released, and the engagement between the engaging pressing portion 42 and the plunger 51 is converted. The conversion structure is constituted by the facing surface 410 of the slide engaging portion 41. In a state where the engagement pressing portion 42 and the plunger 51 are engaged, the engagement target faces the contact portion 43 in the front-rear direction.
The abutting portion 43 is configured to abut against an engagement object (finger clip 54) facing in the front-rear direction in a state where the engaging pressing portion 42 and the plunger 51 are engaged with each other, thereby preventing the operating member 4 from advancing (sliding) in the pricking direction, that is, preventing the plunger 51 from being pushed in.
In the present embodiment, in a state where the abutting portion 43 is provided behind the engagement target, the amount of insertion of the operation member into the housing 2 is larger in a state where the engagement pressing portion 42 is provided behind the engagement target (that is, neither the slide engagement portion 41 nor the abutting portion 43 is behind the engagement target (finger clip 54) than in a state where the operation member 4 is inserted into the housing 2.
Therefore, the overlap amount of the operation member 4 and the close contact portion 24 in the state where the engagement pressing portion 42 is provided behind the engagement target is larger than the overlap amount of the operation member 4 and the close contact portion 24 in the state where the contact portion 43 is provided behind the engagement target.
In any state, the housing space formed by the housing 2 and the operation member 4 is in a sealed state, and the operation member 4 can be removed from the housing 2 by locking the operation member 4 to the close contact portion 24 in a state where the abutting portion 43 is provided behind the engagement target. On the other hand, in a state where the engagement pressing portion 42 is provided behind the engagement target, the operation member 4 is locked and locked at the contact portion 24 to prevent the operation member 4 from being detached from the housing 2.
As described above, the tight contact portion 24 has a function of fixing the operation member 4 and the housing 2 in a state where the accommodation space is sealed, and has a seal locking function of preventing the operation member 4 from sliding with respect to the housing 2 in a state where the accommodation space is sealed.
And a stepped portion 44 formed by opening a notch 440 on the inner circumferential surface side of the opening end of the operation member 4. Thus, the stepped portion 44 includes an outer surface portion 441 located on the inner peripheral surface of the operation member 4 in the order from the opening end of the operation member 4 and closer to the radially outer side of the operation member 4, a vertical surface portion 442 standing from the axially inner end portion of the outer surface portion 441 toward the radially inner side of the operation member 4, and an inner surface portion 443 formed on the inner peripheral surface of the operation member 4 and connected to the radially inner end portion of the vertical surface portion 442.
The first guided portion 400 and the second guided portion 401 are connected to the notch portion 440, and are formed to extend from the notch portion 440 to one end side.
The inner diameter of the outer surface 441 of the stepped portion 44 is smaller than the outer diameter of the front ring 241 of the contact portion 24, and when the operation member 4 is fitted to the housing 2, the outer surface 441 is expanded in diameter by the tapered ring portion 240 and is in close contact with the front ring 241, and the corner formed by the vertical surface 442 and the inner surface 443 is in close contact with the tapered ring portion 240. Therefore, when the overlap amount between the operation member 4 and the close contact portion 24 is small, the outer surface portion 441 contacts the rear side of the front ring 241, and the corner portion contacts the rear side (the portion with a small outer diameter) of the tapered ring portion 240, so that the stepped portion 44 of the operation member 4 is fitted to the close contact portion 24 with a weak force. When the overlap amount between the operation member 4 and the close contact portion 24 is large, the rear side to the front side of the front ring is in close contact with the outer surface portion 441, and the corner portion is in close contact with the front side (portion having a large outer diameter) of the tapered ring portion 240, so that the step portion 44 of the operation member 4 is fitted to the close contact portion 24 with a strong force.
The mixing aid 1 for a syringe according to the present embodiment is configured as described above. Hereinafter, a method of using the mixing aid 1 will be described with reference to fig. 13 to 21.
As shown in fig. 13, the mixing aid 1 is configured such that the sealed container 6 is placed in the housing 2, the syringe 5 is placed in the holder 3, and the holder 3 is inserted into the housing 2 in order to mix the first substance in the sealed container 6 and the second substance in the syringe 5. In addition, the mixing tool 1 requires removal of the fixing material S when it is used.
The movable claw 322 of the holder 3 is fitted in the first guide groove 220a of the housing 2, and the operating member guide portion 23 of the housing 2 is fitted in the first guided portion 400 of the operating member 4. A finger grip 54 as an engagement target is provided in front of the slide engagement portion 41. (see FIG. 17).
When the housing 2 is slid in the pricking direction with respect to the operating member 4, the slide engaging portion 41 engages with the finger grip 54 in the front-rear direction, and the syringe 5 and the holder 3 are slid in the pricking direction in synchronization (see fig. 18). When the housing 2 is slid relative to the operating member 4 in the puncturing direction, the operating member 4 may be pushed toward the housing 2, or the housing 2 may be pushed toward the operating member 4.
At the same time, the sealed container 6 is inserted into the container holding portion 33, the inner claw portion 331 thereof is hooked on the sealed container 6 (the neck portion of the container main body 60), the syringe 5 is also advanced toward the sealed container 6 side along the piercing direction, and the needle 52 protruding from the needle cover 53 penetrates the sealing plug 61 and enters the sealed container 6. At this time, since the movable claws 322 of the holder 3 are fitted into the first guide grooves 220a of the housing 2, the operating member guide portions 23 of the housing 2 are fitted into the first guided portions 400 of the operating member, and the rotation of the holder 3 is restricted.
The pushing in of the operating member 4 is continued, the movable claws 322 of the holder 3 reach the terminal ends of the first guide grooves 220a of the housing 2, and the holder 3 and the syringe 5 cannot advance any more in the above-mentioned piercing direction. As shown in fig. 19, the pushing force (force for rotating finger grip 54) is continuously applied to finger grip 54 from the facing surface 410 of slide engaging portion 41, and syringe 5 rotates together with holder 3.
At this time, as shown in fig. 14, the movable claw 322 (the protruding claw portion 322b) moves from the first guide groove 220a to the second guide groove 220b beyond the protruding portion 221. The finger clip 54 moves from the front of the facing surface 410 of the slide engaging portion 41 to the front of the contact portion 43. That is, the engagement between the finger clip 54 and the facing surface 410 of the slide engaging portion 41 is released, and the operation member 4 can be further pushed in the pricking direction.
As shown in fig. 15 and 20, when the operating member 4 is further pushed, the plunger 51 is pressed by the pressing engagement portion 42. When the second substance filled in the syringe body 50 is powder, only air in the syringe body 50 enters the container body 60 when the plunger 51 is pressed. On the other hand, when the second substance filled in the syringe body 50 is liquid, the second substance in the syringe body 50 enters the container body 60 when the plunger 51 is pressed.
In the present embodiment, when the contact portion 43 is provided behind the engagement target, the engagement pressing portion 42 presses the syringe 51 to the bottom, the operation member 4 and the close contact portion 24 are engaged with each other, the housing space is in a sealed state, and the operation member 4 and the housing 2 are temporarily fixed to each other.
When the second substance filled in the syringe body 50 is liquid, the first substance and the second substance in the sealed container 6 can be mixed by shaking the mixing tool 1. As described above, since the operation member 4 and the housing 2 are temporarily fixed together, the operation member 4 can be prevented from falling off the housing 2 when the mixing assist tool 1 is shaken, and thus the first substance and the second substance are mixed and the mixture obtained by mixing the first substance and the second substance does not leak to the outside, and the safety is improved.
Next, the syringe 5 can be taken out from the inside of the case 2 by pulling the operation member 4 with respect to the case 2 and removing the operation member 4 from the case 2. When the operation member 4 is removed from the housing 2, the second substance (liquid) or air filled in the syringe 5 is injected into the sealed container 6 and the pressure is high, so that the pressing force of the engaging and pressing portion 42 on the plunger 51 is released and the plunger 51 is automatically pushed back as shown in fig. 21.
When the second substance filled in the syringe body 50 is powder, the first substance (liquid) in the sealed container 6 moves toward the syringe body 50 when the syringe 51 is pushed back. When the syringe 51 is pushed back in the case where the second substance filled in the syringe body 50 is a liquid, the medicine formed by mixing the first substance and the second substance in the sealed container 6 moves toward the syringe body 50 under the pressure.
When the medicine in the sealed container 6 is transferred to the syringe body 50, the housing 2 is required to be directed upward and the operation member 4 is required to be directed downward so that the tip of the needle 52 is immersed in the medicine in the sealed container 6. When the first substance or the medicine in the sealed container 6 is moved to the syringe body 50, the medicine in the sealed container 6 can be moved into the syringe 5 by pulling the plunger 51.
Then, with the holder 3 left in the housing 2, the injection is completed using the syringe 5 removed from the holder 3. When the syringe is pulled out from the holder 3, the finger grips 54 of the syringe 5 are removed from the space between the adjacent wall portions 310 of the holder 3 to pull out the syringe from the rear end side.
After the injection is completed, the syringe 5 is inserted into the holder 3 again, and the operating member 4 is externally fitted to the housing 2. In this case, since the movable claws 322 of the holder 3 are fitted into the second guide grooves 220b of the housing 2, the second guided portions 401 are fitted into the operation member guide portions 23, and the finger grips 54 to be engaged are provided at positions where the sub slide engaging portions 41 and the abutting portions 43 are deviated.
The operating member 4 is pushed to slide the operating member 4 in the piercing direction and to be in close contact with the close contact portion 24, and the sliding of the operating member 4 with respect to the housing 2 is restricted in a state where the accommodation space is closed, so that the operating member 4 cannot be removed from the housing 2 (see fig. 16). At this time, the first substance, the second substance, and the mixed medicine in the accommodating space are not exposed to the outside, and the syringe 5 and the sealed container 6 can be discarded.
In the mixing aid 1 for syringe according to the present embodiment, as described above, when the operating member 4 is pressed, the slide engaging portion 41 engages with at least one of the holder 3 and the syringe 5, and the holder 3 slides to the communicating position, whereby the sealed container 6 and the syringe 5 communicate with each other through the needle 52, and the load of the engagement of the slide engaging portion 41 with at least one of the holder 3 and the syringe 5 is released by the pressing force at the time of the pressing operation, and the switching structure is switched to the engagement of the engaging pressing portion 42 with the plunger 51, so that the structural design can reduce the force required for pressing and inserting the plunger 51.
Further, the mixing aid 1 can suppress the load applied to the operation member 4 when the plunger 51 is pressed in, that is, the force necessary to slide the operation member 4. Therefore, the brewing aid 1 of the present embodiment can obtain an excellent effect of being able to easily press the plunger 51.
Further, the switching structure can release the engagement state of the slide engagement portion 41 with the engagement object by applying a force in the piercing direction to the operation member 4 and rotating the holder 3 with respect to the operation member 4. The engagement state of the slide engagement portion 41 with at least either the holder 3 or the syringe 5 can be released only by pressing the operation member 4, thereby improving operability.
Further, the holding structure can hold the operation member 4 at a position where the engaging and pressing portion 42 presses the plunger 51 toward the sealed container 6, and therefore, with this holding structure, when the engaging and pressing portion 42 presses the plunger 51 toward the sealed container 6, the operation member 4 and the housing 2 are held and fixed, and the operation member 4 is hardly detached from the housing 2. Thus, when the second substance filled in the syringe body 50 is a liquid and the mixing aid 1 is shaken, the safety can be improved when the first substance and the second substance in the sealed container 6 are mixed.
Further, a lock structure is provided between the housing 2 and the operation member 4, the lock structure maintaining the housing space in a sealed state in a state where the syringe 5 is built in the holder 3 and being capable of restricting the relative sliding between the housing 2 and the operation member 4, for example, when the syringe 5 is built in the holder 3 after injection use and the holder 3 is located in the housing space, the housing space is in a sealed state and the relative sliding between the housing 2 and the operation member 4 is restricted (that is, the operation member 4 cannot be detached from the housing 2) due to the lock structure, thereby preventing the exposure of the first substance, the second substance, and the mixed medicine.
The insertion opening O of the holder 3 is formed so that the outside inner diameter is larger than the inside inner diameter in the insertion direction of the syringe 5, so that when the syringe 5 is inserted into the insertion opening of the holder 3 from the needle 52, the needle 52 hardly comes into contact with the insertion opening O, and the needle 52 is prevented from being bent and broken.
The mixing aid of the present embodiment is not limited to the above-described embodiment, and various modifications may be made without departing from the scope of the present invention.
Although not particularly mentioned in the above embodiment, the first substance filled in the container main body 60 and the second substance filled in the syringe main body 50 may be of different types or the same type.
In the above embodiment, although not particularly mentioned, in the case where the second substance filled in the syringe body 50 is in a powder form, the needle cap 53 may not be provided.
In the above embodiment, a method of using the mixing aid 1 will be described by taking an example of transferring a medicine formed by mixing a first substance and a second substance in the sealed container 6 from the sealed container 6 into the syringe body 50. Of course, the first substance in the sealed container 6 may also move towards the syringe body 50.
Although not particularly mentioned in the above embodiment, as shown in fig. 22, the cylindrical portion 530 of the needle cap 53 may have a flexible sheet-like structure, and the proximal end portion of the cylindrical portion 530 is externally fitted to the needle base 520, and the needle base 520 is externally fitted to the nozzle 500, and when the nozzle 500 is pressed against the sealing portion 531, the central portion of the cylindrical portion 530 is bent, and the needle head moves forward. Thereby, the needle 52 can advance toward the front end of the sealing portion 531.
As shown in fig. 23, the cylindrical portion 530 may have a bellows shape. In this case, the proximal end portion of the cylindrical portion 530 is fitted over the needle base 520, the needle base 520 is fitted over the nozzle 500, and when the nozzle 500 is pressed against the seal portion 531, the cylindrical portion 530 is contracted (contracted in the axial direction), and the needle 52 moves forward. Thereby, the needle tip 52 advances toward the front end of the sealing portion 53.
In the above embodiment, the needle 520 has a proximal end connected to the needle base 520, and a distal end thereof moves toward the hermetic container 6 with the syringe 5 in the accommodation space to pierce the sealing plug 61. But it is not limited to the above-described structure. For example, needle 52 may be configured as: when the syringe 5 located in the housing space is moved toward the hermetic container 6, the tip end portion of the needle 52 pierces the sealing plug 61, and the base end portion pierces the sealing member covering the opening at the tip end of the nozzle 500.
In this case, the needle head 52 may be a double-ended needle having a sharp proximal end portion and a sharp distal end portion. In addition, as shown in fig. 24, when the needle head 52 is of a two-headed needle structure, a needle unit 7 for fixing the needle head 52 needs to be provided.
Hereinafter, the needle unit 7 will be described by replacing the needle head 52 with the double-ended needle 52. As shown in fig. 25, the needle unit 7 is composed of two parts, namely, a fixing part 70 which is externally fitted to a nozzle 500 of the syringe 5 and extends forward along the nozzle 500, and a holding part body 71 which is slidable forward and backward in the puncturing direction with respect to the fixing part 70. The holding portion main body 71 fixes the double-ended needle such that the needle head on the distal end side and the needle head on the proximal end side are always in a state of extending in the puncture direction.
The fixing portion 70 has a cylindrical shape and is configured to allow the nozzle 500 to be inserted into the proximal end portion side. More specifically, the fixing portion 70 includes an outer cylindrical portion 700 externally fitted to the nozzle 500 and an extended cylindrical portion 701 having a cylindrical shape and extending from a distal end of the outer cylindrical portion 700.
The nozzle 500 may be pressed into the outer insert cylinder 700.
A hook lock 501 (see fig. 27) is provided around the nozzle 500, and a female screw formed on an inner peripheral surface of the hook lock 501 is screwed with a male screw on an outer peripheral surface of the externally fitted cylinder portion 700. If the hook lock 501 is not disposed around the nozzle, the outer cylindrical fitting part 700 may be fixed to the syringe 5 only by pressing the nozzle 500. In this case, the outer circumferential surface of the externally fitted cylindrical portion 700 is not designed with external threads.
The inner peripheral surface of the extended cylinder part 701 on the distal end side and the inner peripheral surface on the proximal end side are each formed with a recess. (hereinafter, the concave portion formed on the inner peripheral surface on the distal end side is referred to as a first concave portion 701a, and the concave portion formed on the inner peripheral surface on the proximal end side is referred to as a second concave portion 701 b).
The first recess 701a and the second recess 701b are continuously formed around the entire inner circumferential surface of the extended cylinder 701. That is, the first recess 701a and the second recess 701b are annular grooves. The first recess 701a and the second recess 701b are formed linearly in parallel in the piercing direction, the second recess 701 is provided in front of the tip of the nozzle 500, and when the sealing member 500a for closing the opening is provided at the tip of the nozzle 500, the second recess 701b is provided in front of the sealing member 500a. (see FIG. 27)
A groove-shaped slide guide 701c extending straight in the piercing direction and connected to the first recess 701a and the second recess 701 is formed on the inner peripheral surface of the extension tube 701.
The holding portion main body 71 may be capable of moving forward in the puncturing direction with respect to the fixing portion 70, or may be capable of moving backward from the forward position.
The holding portion body 71 includes: a sliding cylinder part 710 having a cylindrical shape and slidably fitted into the extended cylinder part 701, a needle fixing part 711 for fixing the double-headed needles 52 positioned in the sliding cylinder part 710, and an engaging protrusion 712 protruding from an outer surface of the sliding cylinder part 710 and engageable with the first recess 701a and the second recess 701b.
The engaging protrusion 712 can move between the first recess 701a and the second recess 701b by the slide guide 701c. The engaging projection 712 engages with the first recess 701a when the fixing portion main body 71 is in the forward state, and engages with the second recess 701b when the fixing portion main body 71 is in the backward state.
Therefore, the holding portion main body 71 is fixed in position by the engagement of the first concave portion 701a with the engaging projection 712 in the forward state, and is fixed in position by the engagement of the second concave portion 701b with the card and the projection 712 in the backward state. That is, in the needle unit 7, the first recess 701a, the second recess 701b, and the engaging projection 712 constitute a positioning structure (no reference numeral) capable of positioning the holding portion main body 71 at the fixing position in the forward state and the fixing position in the backward state.
The holding portion main body 71 is provided so as to face the sealing member (the tip of the nozzle 500) when the base end side needle tip of the double-ended needle 52 fixed to the needle fixing portion 711 is exposed from the rear side of the sliding tube portion 710, and so as to face the sealed container 6 (the sealing plug 61) when the tip end side needle tip is exposed from the front side of the sliding tube portion 710 (see fig. 26).
Further, as shown in fig. 27, the holding portion main body 71 is provided in the holder 3, and in a state of being positioned in the holder 3, the needle fixing portion 711 is positioned inside the container fixing portion 33 in the width direction of the holder 3 and is provided on the rear side of the inner claw portion 331 in the puncturing direction.
When the needle unit 7 is used in the mixing aid 1, as shown in fig. 26, when the syringe 5 before use is set in the housing space, the base ends of the double-ended needles 52 are disposed to face the tip ends (seal material portions 500a) of the nozzles 500, and the tip ends of the double-ended needles 52 are disposed to face the seal plugs 61.
Then, as shown in fig. 28, when the finger grip 54 is pushed by the slide engaging portion 41 and the holder 3 and the syringe 5 are slid toward the sealed container 6, the entire needle unit 7 moves forward toward the sealed container 6, and the tips of the two needles 52 pierce the sealing plug 61.
At this time, the engaging projection 712 engages with the first recess 701, and the forward state of the fixing portion main body 71 is maintained by the engaging force between the engaging projection 712 and the first recess 701a. That is, the holding portion main body 71 does not move backward in the puncturing direction with respect to the fixing portion 70. Therefore, the needle tips on the proximal end sides of the double-ended needles 52 are also kept in a state of facing the sealing material portion 500a of the nozzle 500.
The holder 3 and the syringe 5 continue to slide toward the sealed container 6, and the tip of the sliding tube 710 hits the sealing plug 61, so that the holder body 71 and the double-ended needle 52 stay at the positions. When the force for advancing the fixing portion 70 exceeds the engaging force between the engaging projection 712 and the first recess 701a, the engaging relationship between the engaging projection 72 and the first recess 70 is released, and the fixing portion 70 moves forward relative to the holding portion main body 71. At the same time, as shown in fig. 29, the sealing member 500a also moves toward the needle tips on the proximal end sides of the two-headed needles 52, and the needle tips on the proximal end sides of the two-headed needles 52 penetrate the sealing member 500a.
The engagement between the engaging projection 712 and the second recess 701b maintains the retracted state of the holding portion main body 71.
In the needle unit 7, the slide cylinder portion 710 is fitted into the extension cylinder portion 701, but the configuration is not limited thereto. For example, the sliding cylinder 710 may be externally fitted to the extended cylinder 701. In this case, the first recess 701a, the second recess 701b, and the guide groove are formed on the outer peripheral surface of the extended cylinder part 701, and the engaging projection 712 is formed on the inner peripheral surface of the sliding cylinder part 710.
In the needle unit 7, the first recess 701a and the second recess 701b are formed in the extended cylinder 701, and the engaging projection 712 is formed in the sliding cylinder 710. For example, the first recess 701a and the second recess 701b are formed in the slide cylinder portion 710, and the engaging projection 712 is formed in the extension cylinder portion 701.
The automatic cleaning device comprises a mixing auxiliary tool 1, a shell 2, a support 3, an operating member 4, an operating member 5, an injector, a sealed container 6, a hand unit 7, a shell body 20, a shell body part 21, a positioning part 22, a support guiding part 23, an operating member guiding part 24, a sealing part 30, a containing part 31, an anti-dropping part 32, an extending part 33, a container fixing part 40, a guided part 41, a sliding clamping part 42, a clamping and pushing part 42, an abutting part 43, an injector body 50, a plunger 51, a plunger 52, a needle head 53, a needle cap 54, a finger clamp 60, a container body 61, a sealing bolt 70, a fixing part 71, a holding part body 210, a bottom bearing part 211, a transverse limiting part 220, a guide groove 220a first guide groove 220b, a second guide groove 221, a protruding part 240, a conical ring part 241, a front side ring 310, a wall part 211, a transverse limiting part 211, a guide groove 220, a guide groove 240, a conical ring part, a conical part, a, 311. The needle comprises an upright part, a 312 extending part, a 320 long plate part, a 321 connecting plate, a 322 movable claw, a 322a bendable part, a 322b protruding claw part, a 330 bendable rod part, a 331 inner claw part, a 400 first guided part, a 401 second guided part, a 410 opposite surface, a 500 nozzle, a 500a sealing part, a 501 hook lock, a 520 needle base, a 530 cylindrical part, a 531 sealing part, a 700 outer embedded cylinder part, a 701 extending cylinder part, a 701a first concave part, a 701b second concave part, a 701c sliding guide part, a 710 sliding cylinder part, a 711 needle fixing part, a 712 clamping protrusion and an O insertion inlet part.
Claims (5)
1. A mixing aid for a syringe, comprising:
a housing in which a sealed container filled with a first substance for mixing is provided;
a holder for fixing a syringe in which a plunger is disposed and a second substance for mixing is filled;
the shell and the bracket are arranged along a puncturing direction for puncturing the sealed container by a needle which enables the syringe and the sealed container to be communicated, and the shell and the bracket are relatively slidably moved to a position where the sealed container is communicated with the syringe by the needle;
an operation member including a slide engagement portion and a press engagement portion; wherein,
a slide engaging portion that is capable of sliding the holder to the communication position with respect to the housing in an engaged state in which at least one of the holder and the syringe is engaged with an engagement target;
a pressing engagement portion that can press the plunger toward the sealed container when the plunger of the syringe provided at the communication position is in an engaged state;
a switching structure is provided between the engagement object and the operation member, and the switching structure releases the engagement state between the slide engagement portion and the engagement object by applying a pressing force to the operation member in the puncturing direction, and switches to engagement between the pressing engagement portion and the plunger.
2. The mixing aid for a syringe according to claim 1, wherein the switching structure causes the holder to rotate in a circumferential direction with respect to the operating member about a virtual line extending in the puncture direction by applying a pressing force in the puncture direction to the operating member, thereby releasing the engagement state between the slide engagement portion and the engagement object.
3. The mixing aid for a syringe according to claim 1 or 2, wherein the housing and the operating member are each of a cylindrical structure, and are insertable into the holder in respective axial directions; the operating component is sleeved outside the shell, and an accommodating space capable of accommodating the bracket is formed between the operating component and the shell, so that the bracket fixed with the injector is arranged between the shell and the operating component; the accommodating space is in a sealed state and is provided with a sealing lock for limiting relative movement between the shell and the operating member.
4. The mixing aid for syringe according to any one of claims 1 to 3, wherein a holding structure capable of fixing the operation member in the housing is provided at a position where the pressing engagement portion pushes the plunger toward the sealed container.
5. The mixing aid for a syringe according to any one of claims 1 to 4, wherein the needle is provided at a tip end of the syringe, the holder is provided with a cylindrical insertion port for fixing the syringe, and the syringe is inserted into the insertion port from a needle side; the insertion opening has an outer inner diameter larger than an inner diameter of the insertion opening in the insertion direction of the syringe.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019-062318 | 2019-03-28 | ||
JP2019062318A JP7174953B2 (en) | 2019-03-28 | 2019-03-28 | Preparation aid for syringes |
PCT/JP2020/014092 WO2020196848A1 (en) | 2019-03-28 | 2020-03-27 | Preparation aid for syringe |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113631134A true CN113631134A (en) | 2021-11-09 |
CN113631134B CN113631134B (en) | 2024-04-12 |
Family
ID=72609552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202080025903.9A Active CN113631134B (en) | 2019-03-28 | 2020-03-27 | Mixing auxiliary tool for syringe |
Country Status (3)
Country | Link |
---|---|
JP (1) | JP7174953B2 (en) |
CN (1) | CN113631134B (en) |
WO (1) | WO2020196848A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3103497A1 (en) * | 2020-12-22 | 2022-06-22 | Duoject Medical Systems Inc. | Secure reconstitution device |
WO2024057691A1 (en) * | 2022-09-14 | 2024-03-21 | ニプロ株式会社 | Drug administering tool |
Citations (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1241571A (en) * | 1968-04-08 | 1971-08-04 | David Slome | Improvements in and relating to hypodermic syringes |
GB1452418A (en) * | 1974-05-07 | 1976-10-13 | Larson R R | Seal puncturing device for container |
CN1119412A (en) * | 1993-03-15 | 1996-03-27 | 伊莱利利公司 | Cartridge assembly for a lyophilized compound forming a disposable portion of an injector pen and method for same |
CN1133003A (en) * | 1993-09-07 | 1996-10-09 | 生物技术公司 | Syringe device for mixing two compounds |
FR2789369A1 (en) * | 1999-02-10 | 2000-08-11 | Biodome | CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE |
US6209738B1 (en) * | 1998-04-20 | 2001-04-03 | Becton, Dickinson And Company | Transfer set for vials and medical containers |
KR20030014785A (en) * | 2001-08-13 | 2003-02-20 | 주식회사 부윤테크 | Container plus syringe system |
ITMO20030057A0 (en) * | 2003-03-04 | 2003-03-04 | Sidam Di Azzolini Graziano E C | DEVICE FOR THE PACKAGING, MIXING AND APPLICATION OF BONE CEMENT. |
US20030055395A1 (en) * | 2000-02-15 | 2003-03-20 | Manera David A. | Needleless access apparatus and system |
US6581648B1 (en) * | 1998-10-30 | 2003-06-24 | Immunex Corporation | Method and apparatus for operating a syringe and vial for injections |
US20050070853A1 (en) * | 2003-08-25 | 2005-03-31 | Brian Gatton | Medicament dispensing assembly |
US20060079834A1 (en) * | 2004-10-13 | 2006-04-13 | Hyprotek, Inc. | Syringe devices and methods for mixing and administering medication |
CN101115457A (en) * | 2005-02-09 | 2008-01-30 | 科研制药株式会社 | Syringe device and method of preparing medicine using the device |
US20080188799A1 (en) * | 2004-07-24 | 2008-08-07 | Bayer Healthcare Llc | Medical Reconstitution System with Improved Syringe |
US20090326448A1 (en) * | 2006-04-18 | 2009-12-31 | Pingan Huo | Sterile Drug-Mixing Syringe |
JP2010528789A (en) * | 2007-06-13 | 2010-08-26 | デュオジェクト・メディカル・システムズ・インコーポレイテッド | Device for transferring liquid from cartridge to container |
CN102015014A (en) * | 2008-05-02 | 2011-04-13 | 泰尔茂株式会社 | Connector assembly |
US20120123382A1 (en) * | 2009-07-15 | 2012-05-17 | Tomohiko Kubo | Connection device |
CN102481228A (en) * | 2009-09-08 | 2012-05-30 | 泰尔茂株式会社 | Mixing apparatus and piercing method for a double-ended needle |
CN102834134A (en) * | 2010-03-31 | 2012-12-19 | 泰尔茂株式会社 | Prefilled syringe |
CN103491926A (en) * | 2011-04-14 | 2014-01-01 | 株式会社Jms | Medical port, nutrient container employing same, and nutrient supply set |
CN103501750A (en) * | 2011-05-02 | 2014-01-08 | 株式会社盛本医药 | Container for administering medication |
JP2014528337A (en) * | 2011-10-14 | 2014-10-27 | ノボ ノルディスク ヘルス ケア アーゲー | Pre-assembled fluid transfer device |
US20140360623A1 (en) * | 2011-12-08 | 2014-12-11 | Novo Nordisk Healthcare Ag | Medical Device Having Integrated Sequence Control |
CN104512635A (en) * | 2013-09-30 | 2015-04-15 | 株式会社松风 | Two-component mixing container with communication passage of liquid-tight structure |
CN104640586A (en) * | 2013-01-15 | 2015-05-20 | 泰尔茂株式会社 | Liquid dispenser |
US20160082201A1 (en) * | 2014-09-24 | 2016-03-24 | Ralph P. Stillman | Syringe injection aid |
US20160258849A1 (en) * | 2015-03-02 | 2016-09-08 | Seiko Epson Corporation | Container, biologically relevant material purification cartridge, and biologically relevant material purification cartridge assembly kit |
US20180036204A1 (en) * | 2012-07-12 | 2018-02-08 | Antares Pharma, Inc. | Liquid-Transfer Adapter Beveled Spike |
CN108135777A (en) * | 2015-09-30 | 2018-06-08 | 科研制药株式会社 | For connecting the injection device and its method of two kinds of substances |
CN109010042A (en) * | 2018-08-02 | 2018-12-18 | 杭州泰林精密仪器有限公司 | A kind of packing method and structure of confection |
-
2019
- 2019-03-28 JP JP2019062318A patent/JP7174953B2/en active Active
-
2020
- 2020-03-27 WO PCT/JP2020/014092 patent/WO2020196848A1/en active Application Filing
- 2020-03-27 CN CN202080025903.9A patent/CN113631134B/en active Active
Patent Citations (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1241571A (en) * | 1968-04-08 | 1971-08-04 | David Slome | Improvements in and relating to hypodermic syringes |
GB1452418A (en) * | 1974-05-07 | 1976-10-13 | Larson R R | Seal puncturing device for container |
CN1119412A (en) * | 1993-03-15 | 1996-03-27 | 伊莱利利公司 | Cartridge assembly for a lyophilized compound forming a disposable portion of an injector pen and method for same |
CN1133003A (en) * | 1993-09-07 | 1996-10-09 | 生物技术公司 | Syringe device for mixing two compounds |
US6209738B1 (en) * | 1998-04-20 | 2001-04-03 | Becton, Dickinson And Company | Transfer set for vials and medical containers |
US6581648B1 (en) * | 1998-10-30 | 2003-06-24 | Immunex Corporation | Method and apparatus for operating a syringe and vial for injections |
FR2789369A1 (en) * | 1999-02-10 | 2000-08-11 | Biodome | CONNECTION DEVICE BETWEEN A CONTAINER AND A CONTAINER AND READY-TO-USE ASSEMBLY COMPRISING SUCH A DEVICE |
US20030055395A1 (en) * | 2000-02-15 | 2003-03-20 | Manera David A. | Needleless access apparatus and system |
KR20030014785A (en) * | 2001-08-13 | 2003-02-20 | 주식회사 부윤테크 | Container plus syringe system |
ITMO20030057A0 (en) * | 2003-03-04 | 2003-03-04 | Sidam Di Azzolini Graziano E C | DEVICE FOR THE PACKAGING, MIXING AND APPLICATION OF BONE CEMENT. |
US20050070853A1 (en) * | 2003-08-25 | 2005-03-31 | Brian Gatton | Medicament dispensing assembly |
US20080188799A1 (en) * | 2004-07-24 | 2008-08-07 | Bayer Healthcare Llc | Medical Reconstitution System with Improved Syringe |
US20060079834A1 (en) * | 2004-10-13 | 2006-04-13 | Hyprotek, Inc. | Syringe devices and methods for mixing and administering medication |
CN101115457A (en) * | 2005-02-09 | 2008-01-30 | 科研制药株式会社 | Syringe device and method of preparing medicine using the device |
US20090326448A1 (en) * | 2006-04-18 | 2009-12-31 | Pingan Huo | Sterile Drug-Mixing Syringe |
JP2010528789A (en) * | 2007-06-13 | 2010-08-26 | デュオジェクト・メディカル・システムズ・インコーポレイテッド | Device for transferring liquid from cartridge to container |
CN102015014A (en) * | 2008-05-02 | 2011-04-13 | 泰尔茂株式会社 | Connector assembly |
US20120123382A1 (en) * | 2009-07-15 | 2012-05-17 | Tomohiko Kubo | Connection device |
CN102481228A (en) * | 2009-09-08 | 2012-05-30 | 泰尔茂株式会社 | Mixing apparatus and piercing method for a double-ended needle |
CN102834134A (en) * | 2010-03-31 | 2012-12-19 | 泰尔茂株式会社 | Prefilled syringe |
CN103491926A (en) * | 2011-04-14 | 2014-01-01 | 株式会社Jms | Medical port, nutrient container employing same, and nutrient supply set |
CN103501750A (en) * | 2011-05-02 | 2014-01-08 | 株式会社盛本医药 | Container for administering medication |
JP2014528337A (en) * | 2011-10-14 | 2014-10-27 | ノボ ノルディスク ヘルス ケア アーゲー | Pre-assembled fluid transfer device |
US20140360623A1 (en) * | 2011-12-08 | 2014-12-11 | Novo Nordisk Healthcare Ag | Medical Device Having Integrated Sequence Control |
US20180036204A1 (en) * | 2012-07-12 | 2018-02-08 | Antares Pharma, Inc. | Liquid-Transfer Adapter Beveled Spike |
CN104640586A (en) * | 2013-01-15 | 2015-05-20 | 泰尔茂株式会社 | Liquid dispenser |
CN104512635A (en) * | 2013-09-30 | 2015-04-15 | 株式会社松风 | Two-component mixing container with communication passage of liquid-tight structure |
US20160082201A1 (en) * | 2014-09-24 | 2016-03-24 | Ralph P. Stillman | Syringe injection aid |
US20160258849A1 (en) * | 2015-03-02 | 2016-09-08 | Seiko Epson Corporation | Container, biologically relevant material purification cartridge, and biologically relevant material purification cartridge assembly kit |
CN108135777A (en) * | 2015-09-30 | 2018-06-08 | 科研制药株式会社 | For connecting the injection device and its method of two kinds of substances |
CN109010042A (en) * | 2018-08-02 | 2018-12-18 | 杭州泰林精密仪器有限公司 | A kind of packing method and structure of confection |
Non-Patent Citations (2)
Title |
---|
FRID, A.等: "New injection recommendations for patients with diabetes", 《DIABETES & METABOLISM》, vol. 36, no. 2, 1 September 2010 (2010-09-01), pages 3 * |
张景平;张洛嘉;张晓雪;: "软体输液瓶与西林瓶间配药连接器的研发", 医疗卫生装备, no. 05, 15 May 2016 (2016-05-15), pages 40 - 42 * |
Also Published As
Publication number | Publication date |
---|---|
JP7174953B2 (en) | 2022-11-18 |
WO2020196848A1 (en) | 2020-10-01 |
CN113631134B (en) | 2024-04-12 |
JP2020156969A (en) | 2020-10-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5755696A (en) | Syringe filling and delivery device | |
US10888497B2 (en) | Drug reconstitution system | |
US7736353B2 (en) | Pharmaceutical delivery systems and methods for using same | |
US8556879B2 (en) | Connector | |
CN106456443B (en) | Connector for medical container and cover for male member | |
JP3987106B2 (en) | Syringe device | |
US4568346A (en) | Hypodermic syringe having a telescopic assembly between cartridge and medicament holder | |
US20040024354A1 (en) | Transfer device and method for transferring a pharmaceutical component between a vial and a syringe | |
US7882859B2 (en) | System for preparing and making available a flowable medium formed by mixing a dry substance with a fluid | |
CN103501751A (en) | Easy linking transfer system | |
JP6271549B2 (en) | Reconstruction device | |
CN113631134A (en) | Mixing auxiliary tool for syringe | |
JP6046721B2 (en) | Liquid dosing device | |
JPH1189934A (en) | Pre-filled syringe | |
WO2014115241A1 (en) | Liquid dispenser | |
US20190343722A1 (en) | Method and apparatus for filling syringes with retractable needle | |
EP2874594B1 (en) | Reconstitution device with tip cap | |
WO2024057692A1 (en) | Coupling device | |
JP2023183915A (en) | Adapter and syringe with adapter | |
JP2024061056A (en) | Adapter and container with adapter | |
CN117083046A (en) | Coupling tool and device for producing medicament | |
JP2001218843A (en) | Injection syringe and locking tool for injection syringe | |
JP2020156924A (en) | Syringe connecting instrument | |
CN112188881A (en) | Connector for connecting a medical injection device to a container | |
WO2013146049A1 (en) | Liquid administration device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20240111 Address after: B-1001, Huitong Building, No. 22 Pukou Road, Hexi District, Tianjin, 300203 Applicant after: Sheng Ben (Tianjin) International Trading Co.,Ltd. Address before: No. 28, 8-chome, 5-chome, Okinawa ku, Osaka City, Osaka Prefecture, Japan Applicant before: Morimoto Pharmaceutical Co.,Ltd. |
|
GR01 | Patent grant | ||
GR01 | Patent grant |