CN113442188A - Pathological section device based on tumor molecular mechanism research experiment - Google Patents
Pathological section device based on tumor molecular mechanism research experiment Download PDFInfo
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- CN113442188A CN113442188A CN202110067201.3A CN202110067201A CN113442188A CN 113442188 A CN113442188 A CN 113442188A CN 202110067201 A CN202110067201 A CN 202110067201A CN 113442188 A CN113442188 A CN 113442188A
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 26
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 22
- 238000011160 research Methods 0.000 title claims abstract description 22
- 238000002474 experimental method Methods 0.000 title claims abstract description 21
- 230000009456 molecular mechanism Effects 0.000 title claims abstract description 21
- 238000005520 cutting process Methods 0.000 claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 13
- 238000004140 cleaning Methods 0.000 claims description 43
- 230000007246 mechanism Effects 0.000 claims description 34
- 238000005192 partition Methods 0.000 claims description 31
- 230000008878 coupling Effects 0.000 claims description 21
- 238000010168 coupling process Methods 0.000 claims description 21
- 238000005859 coupling reaction Methods 0.000 claims description 21
- 210000001503 joint Anatomy 0.000 claims description 20
- 230000000694 effects Effects 0.000 claims description 13
- 238000007599 discharging Methods 0.000 claims description 9
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 230000006378 damage Effects 0.000 abstract description 3
- 238000012545 processing Methods 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 5
- 239000004744 fabric Substances 0.000 description 5
- 238000013461 design Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000003032 molecular docking Methods 0.000 description 2
- 230000010405 clearance mechanism Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
- B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
- B26D1/04—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member
- B26D1/06—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates
- B26D1/10—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates in, or substantially in, a direction parallel to the cutting edge
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/01—Means for holding or positioning work
- B26D7/02—Means for holding or positioning work with clamping means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/06—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form
- B26D7/0625—Arrangements for feeding or delivering work of other than sheet, web, or filamentary form by endless conveyors, e.g. belts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/08—Means for treating work or cutting member to facilitate cutting
- B26D7/088—Means for treating work or cutting member to facilitate cutting by cleaning or lubricating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/27—Means for performing other operations combined with cutting
- B26D7/32—Means for performing other operations combined with cutting for conveying or stacking cut product
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- Life Sciences & Earth Sciences (AREA)
- Forests & Forestry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention belongs to the technical field of medical instruments, and particularly relates to a pathological section device based on tumor molecular mechanism research experiments. The sample conveying device has the advantages that the sample conveying operation is realized, the intermittent clamping mode can be utilized for feeding materials during cutting, the continuous slicing processing of the sample is facilitated, the cutter can be cleaned during cutting, the phenomenon that the residual substances of the cutter damage the slice during cutting is avoided, the slicing quality is improved, and the phenomenon that the cutter pollutes the slice during cutting is avoided.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a pathological section device based on a tumor molecular mechanism research experiment.
Background
Pathological sections are often required to be made in the process of tumor pathological research, and the pathological section making process generally comprises the following steps: the pathological section device comprises a slicing machine, a sample feeding device, a slicing knife, a cutter, a motor, a power supply and a power supply.
Disclosure of Invention
The pathological section device based on the tumor molecular mechanism research experiment provided by the invention solves the problems in the prior art.
In order to achieve the purpose, the invention adopts the following technical scheme:
a pathological section device based on a tumor molecular mechanism research experiment comprises a box body, wherein a partition plate is arranged in the box body in the vertical direction, a cutter channel penetrates through the partition plate, a cutting and cleaning mechanism is arranged at one end of the cutter channel, a supporting plate which is fixedly connected with the inner side wall of the box body and is arranged in the horizontal direction is arranged above the other end of the cutter channel, a feeding conveying mechanism is arranged at the top of the supporting plate, a discharging channel which penetrates through the box body is arranged below one side of the supporting plate, which is far away from the partition plate, and a sample conveying mechanism is arranged in the discharging channel;
the feeding conveying mechanism comprises a housing fixedly connected with the supporting plate, an opening of the housing is positioned on one side, close to the partition plate, of the housing, a driving shaft is arranged in the vertical direction, a motor fixedly connected with the housing is installed at the top of the driving shaft, a fixed clamping unit is movably sleeved on the outer ring of the driving shaft, a movable clamping unit which is arranged in parallel with the fixed clamping unit and connected with the driving shaft is installed at the top of the fixed clamping unit, a butt joint unit connected with the driving shaft is installed on the movable clamping unit, a switching unit connected with the driving shaft is installed at the top of the movable clamping unit, the switching unit is connected with an adjusting unit arranged in parallel with the driving shaft, the adjusting unit is positioned on one side, far away from the partition plate, of the adjusting unit, an opening and closing unit connected with the fixed clamping unit and the movable clamping unit is installed on one side, far away from the driving shaft, of the adjusting unit, a pushing unit arranged in the vertical direction is installed on the other side of the opening and closing unit, the top output end of the pushing unit is fixedly connected with the inner side wall of the top of the housing, the bottom of the pushing unit is fixedly connected with the supporting plate, and the bottom of the fixed clamping unit is provided with a lifting unit connected with the opening and closing unit.
Preferably, the fixed clamping unit comprises a mounting plate with a hollow structure, a guide plate is mounted inside the mounting plate, the guide plate is connected with movable plates symmetrically arranged along the driving shaft through slide rail sliders, one ends of the movable plates, extending out of the mounting plate, are fixedly connected with clamping plates with a circular arc structure, the guide plate is positioned on one side of the driving shaft, far away from the partition plate, and are respectively provided with a pull rod hinged with the end part of the movable plate, one ends of the two groups of pull rods, far away from the movable plates, are hinged with a push plate with the same L-shaped structure, the push plate is movably sleeved with the mounting plate, a first spring is fixedly connected between the push plate and the guide plate, one end of the push plate, extending out of the mounting plate, is fixedly connected with a frame with a rectangular structure, an adjusting unit is positioned on an inner ring of the frame, one end of the frame, far away from the push plate, is fixedly connected with an open-close plate with a T-close structure, the fixed clamping unit and the movable clamping unit, the mounting plate of the fixed clamping unit is movably sleeved with the driving shaft, the mounting plate of the movable clamping unit is in threaded sleeve joint with the driving shaft.
Preferably, the switching unit adopts any one of a belt pulley or a chain wheel and a chain.
Preferably, the adjusting unit includes the pivot of being connected with the switching unit, and the fixed cover in the outer lane of pivot has connect the sleeve pipe one that sets up along its length direction, and the outer lane rigid coupling of sleeve pipe one has the lug one that sets up along its length direction, and sleeve pipe two that the fixed cup joint in the outer lane of sleeve pipe one bottom was installed and is followed the pivot, and the outer lane rigid coupling of sleeve pipe two has the lug two that sets up along its length direction, and lug two and lug one are along pivot axis symmetric distribution.
Preferably, the opening and closing unit comprises a push-pull plate with a U-shaped structure, the end part of the opening and closing plate extending into the push-pull plate is connected with the adjacent inner side wall of the push-pull plate in a sliding mode, two ends, close to the opening of the frame, of the push-pull plate are fixedly connected with baffles, and one end, far away from the frame, of the push-pull plate is fixedly connected with a first push rod motor fixedly connected with the inner side wall of the housing.
Preferably, the cutting and cleaning mechanism comprises a cutter mounting plate arranged along the horizontal direction, a cutter is arranged at one end of the cutter mounting plate close to the cutter channel, two sides of one end of the cutter mounting plate far away from the cutter are respectively provided with an extrusion plate with a trapezoidal structure, one end of the extrusion plate far away from the cutter mounting plate is fixedly connected with a butt plate, one end of the two groups of butt plates far away from each other is respectively provided with a pushing ring, one side of the two groups of pushing rings close to each other is respectively provided with a front butt rod and a rear butt rod, the front butt rods and the rear butt rods are positioned at two sides of the butt plates, the front butt rods are positioned at one side of the butt plates close to the cutter, the inner ring of the pushing ring is respectively and slidably sleeved with a transverse rod arranged along the horizontal direction, one side of the two groups of transverse rods close to the partition plate is respectively and fixedly connected with a cleaning mounting plate which is slidably connected with the inner side wall of the box body and moves along the vertical direction, one side of the two groups of the cleaning mounting plates close to each other is fixedly connected with a cleaning roller, and a second spring is arranged between the top plate and the cleaning mounting plate.
Preferably, the holding tank that sets up along its length direction is seted up to the one side that the cleaning roller is close to each other, the shrouding of loop configuration is installed to the opening part of holding tank, the shrouding runs through the orifice that has set up along its length direction, the washing strap is installed to the outer convex surface of shrouding, the material loading roller that cup joints with clearance mounting panel activity is installed to one side of cleaning roller, the unloading roller that cup joints with clearance mounting panel activity is installed to the opposite side of cleaning roller, driving motor is all installed to the one end that material loading roller and unloading roller stretched out the clearance mounting panel, wash the strap winding on material loading roller and unloading roller, the feed liquor pipe that cup joints with the cleaning roller is fixed to the one end of holding tank.
Preferably, the lifting unit comprises a driven plate which is connected with the inner side wall of the housing in a sliding manner and moves along the horizontal direction, the bottom of one end, away from the pushing unit, of the driven plate is provided with a placing plate which is arranged along the horizontal direction, one side of the driven plate is provided with a first rack which is arranged along the length direction of the driven plate, one side of the first rack is meshed with a first gear which is movably sleeved with the housing, one side of the first gear is meshed with a second gear which is movably sleeved with the housing, the second gear is meshed with a second rack which is fixedly connected with the outer side wall of the push-pull plate, and the lower part of one side, close to the partition plate, of the housing is penetrated with a discharge channel.
Preferably, sample conveying mechanism includes the extension board with layer board bottom rigid coupling, and extends to the inside of box from discharge passage to the extension board, and the chain of loop configuration is installed to the bottom of extension board, and the inner circle of chain one is connected with sprocket one, and the inner circle of chain one is fixed to be cup jointed the dwang that cup joints with the extension board activity, the motor two with the inside wall rigid coupling of box is installed to the bottom of dwang, and the outer lane rigid coupling of chain one has the connecting plate that sets up along its length direction, and the top rigid coupling of connecting plate has the top to be provided with the open-ended and holds the box.
Preferably, a driving plate of an L-shaped structure is installed on one side, away from the cutter, of the cutter mounting plate, and a second push rod motor fixedly connected with the box body is installed at the top of the driving plate.
In the present invention,
through the box that sets up, the baffle, the cutter passageway, cutting clearance mechanism, the layer board, discharge passage, sample conveying mechanism, material loading conveying mechanism and lift the unit, make this design realize the transport operation of sample, can utilize intermittent type centre gripping mode to carry out the pay-off in the cutting, make things convenient for the continuous section processing of sample, can clear up the cutter simultaneously in the cutting, avoid the remaining material of cutter to lead to the fact the destruction to the piece in the cutting, improve sliced quality, avoid the cutter to pollute the piece in the cutting simultaneously.
Drawings
FIG. 1 is a schematic structural diagram of a pathological section device based on a tumor molecular mechanism research experiment according to the present invention;
FIG. 2 is a schematic structural diagram of a feeding and conveying mechanism of a pathological section device based on a tumor molecular mechanism research experiment, according to the present invention;
FIG. 3 is a schematic structural diagram of a cutting and cleaning mechanism of a pathological section device based on a tumor molecular mechanism research experiment, according to the present invention;
FIG. 4 is a schematic structural diagram of a fixing and clamping unit of a pathological section device based on a tumor molecular mechanism research experiment, according to the present invention;
fig. 5 is a schematic structural diagram of a pathological section apparatus docking unit based on a tumor molecular mechanism research experiment according to the present invention.
In the figure: 1 box body, 2 clapboards, 3 cutter channels, 4 cutting and cleaning mechanisms, 5 supporting plates, 6 discharging channels, 7 sample conveying mechanisms, 9 feeding conveying mechanisms, 10 lifting units, 21 mounting plates, 22 movable plates, 23 clamping plates, 24 pull rods, 25 push plates, 26 guide plates, 27 frames, 28 opening plates, 31 rotating shafts, 32 sleeve pipes, 33 bump I, 41 cutter mounting plates, 42 extrusion plates, 43 abutting plates, 44 pushing rings, 45 front end abutting rods, 46 rear end abutting rods, 17 cleaning mounting plates, 48 cleaning rollers, 49 top plates, 410 spring II, 411 cutters, 412 cross rods, 51 adapter rings, 52 adjusting plates, 53 rotating plates, 54 holding plates, 61 storage tanks, 62 sealing plates, 63 cleaning cloth belts, 71 push-pull plates, 72 push rod motors I, 91 housings, 93, driving shaft 94 fixed clamping units, 95 movable clamping units, 96 adapter units, 97 adjusting units, 98 opening and closing units, 99 to push the unit.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Referring to fig. 1-5, a pathological section device based on tumor molecular mechanism research experiment comprises a box body 1, a partition plate 2 arranged along the vertical direction is arranged inside the box body 1, a cutter channel 3 penetrates through the partition plate 2, a cutting and cleaning mechanism 4 is arranged at one end of the cutter channel 3, a supporting plate 5 fixedly connected with the inner side wall of the box body 1 and arranged along the horizontal direction is arranged above the other end of the cutter channel 3, a feeding and conveying mechanism 9 is arranged at the top of the supporting plate 5, a discharging channel 6 penetrating through the box body 1 is arranged below one side of the supporting plate 5 far away from the partition plate 2, and a sample conveying mechanism 7 is arranged inside the discharging channel 6;
further, the feeding conveying mechanism 9 comprises a cover 91 fixedly connected with the supporting plate 5, an opening of the cover 91 is positioned at one side of the cover 91 close to the partition plate 2, a driving shaft 93 arranged along the vertical direction is installed inside the cover 91, a fixed clamping unit 94 is movably sleeved on the outer ring of the driving shaft 93, a movable clamping unit 95 which is arranged in parallel with the fixed clamping unit 94 and connected with the driving shaft 93 is installed at the top of the fixed clamping unit 94, a butt joint unit connected with the driving shaft 93 is installed on the movable clamping unit 95, a switching unit 96 connected with the driving shaft 93 is installed at the top of the movable clamping unit 95, the switching unit 96 is connected with an adjusting unit 97 arranged in parallel with the driving shaft 93, the adjusting unit 97 is positioned at one side of the driving shaft 93 far away from the partition plate 2, and an opening and closing unit 98 connected with the fixed clamping unit 94 and the movable clamping unit 95 is installed at one side of the adjusting unit 97 far away from the driving shaft 93, the other side of the opening and closing unit 98 is provided with a pushing unit 99 arranged along the vertical direction, the top output end of the pushing unit 99 is fixedly connected with the inner side wall of the top of the housing 91, the bottom of the pushing unit 99 is fixedly connected with the supporting plate 5, and the bottom of the fixed clamping unit 94 is provided with a lifting unit 10 connected with the opening and closing unit 98.
Specifically, the fixed clamping unit 94 includes a mounting plate 21 with a hollow structure, a guide plate 26 is mounted inside the mounting plate 21, the guide plate 26 is connected to movable plates 22 symmetrically arranged along a driving shaft 93 through slide rails and sliders, clamping plates 23 with circular arc structures are fixedly connected to ends of the movable plates 22 extending out of the mounting plate 21, the guide plate 26 is located on one side of the driving shaft 93 away from the partition plate 2, pull rods 24 hinged to ends of the movable plates 22 are mounted on one sides of the guide plate 26 away from the driving shaft 93, push plates 25 with the same L-shaped structure are hinged to ends of the two groups of pull rods 24 away from the movable plates 22, the push plates 25 are movably sleeved with the mounting plate 21, a first spring is fixedly connected between the push plates 25 and the guide plate 26, a frame 27 with a rectangular structure is fixedly connected to one end of the push plate 25 extending out of the mounting plate 21, the adjusting unit 97 is located on an inner ring of the frame 27, and an open plate 28 with a T-shaped structure is fixedly connected to one end of the frame 27 away from the push plate 25, the fixed clamping unit 94 and the movable clamping unit 95 have the same structure, the mounting plate 21 of the fixed clamping unit 94 is movably sleeved with the driving shaft 93, and the mounting plate 21 of the movable clamping unit 95 is in threaded sleeve with the driving shaft 93;
the outer side of the mounting plate 21 of the fixed clamping unit 94 is provided with a first transverse sliding mechanism which is arranged along the horizontal direction and is connected with the housing 91, the outer side of the mounting plate 21 of the movable clamping unit 95 is provided with a second transverse sliding mechanism which is arranged along the horizontal direction, the second transverse sliding mechanism is provided with a first vertical sliding mechanism which is connected with the housing 91, and the first transverse sliding mechanism, the second transverse sliding mechanism and the first vertical sliding mechanism all adopt slide rail slide blocks.
In particular, the adaptor unit 96 employs either a belt pulley or a sprocket chain.
It should be noted that the adjusting unit 97 includes a rotating shaft 31 connected to the adapting unit 96, a first sleeve 32 fixedly sleeved on an outer ring of the rotating shaft 31 along a length direction thereof, a first projection 33 fixedly connected to an outer ring of the first sleeve 32 along the length direction thereof, a second sleeve fixedly sleeved on the outer ring of the rotating shaft 31 at a bottom of the first sleeve 32, a second projection fixedly connected to an outer ring of the second sleeve along the length direction thereof, and the second projection and the first projection 33 are symmetrically distributed along an axis of the rotating shaft 31.
In addition, the opening and closing unit 98 includes a push-pull plate 71 with a U-shaped structure, the end of the opening and closing plate 28 extending into the push-pull plate 71 is slidably connected to the adjacent inner side wall of the push-pull plate 71, two ends of the push-pull plate 71 near the opening of the frame 27 are fixedly connected with a baffle, and one end of the push-pull plate 71 far from the frame 27 is fixedly connected with a push rod motor 72 fixedly connected to the inner side wall of the housing 91.
Besides, the cutting and cleaning mechanism 4 includes a cutter mounting plate 41 arranged along the horizontal direction, a cutter 411 is installed at one end of the cutter mounting plate 41 close to the cutter channel 3, an extrusion plate 42 with a trapezoidal structure is installed at both sides of one end of the cutter mounting plate 41 far away from the cutter 411, a butt plate 43 is fixedly connected to one end of the extrusion plate 42 far away from the cutter mounting plate 41, a push ring 44 is installed at one end of each of two sets of butt plates 43 far away from each other, a front butt rod 45 and a rear butt rod 46 are installed at one side of each of two sets of push rings 44 close to each other, the front butt rod 45 and the rear butt rod 46 are located at both sides of the butt plate 43, the front butt rod 45 is located at one side of the butt plate 43 close to the cutter 411, a cross rod 412 arranged along the horizontal direction is slidably sleeved on an inner ring of the push ring 44, a cleaning mounting plate 47 slidably connected to the inner side wall of the box 1 and moving along the vertical direction is fixedly connected to one side of the two sets of the cross rods 412 close to the partition 2, the cleaning rollers 48 are fixedly connected to one sides, close to each other, of the two groups of cleaning mounting plates 47, the top plates 49 fixedly connected with the box body 1 are mounted on one sides, far away from each other, of the two groups of cleaning mounting plates 47, and two springs 410 are mounted between the top plates 49 and the cleaning mounting plates 47.
The first embodiment is as follows:
one side that cleaning roller 48 is close to each other sets up along the holding tank 61 that its length direction set up, the shrouding 62 of loop configuration is installed to the opening part of holding tank 61, shrouding 62 runs through the orifice that has its length direction of edge to set up, cleaning cloth belt 63 is installed to the evagination face of shrouding 62, the material loading roller that cup joints with clearance mounting panel 47 activity is installed to one side of cleaning roller 48, the unloading roller that cup joints with clearance mounting panel 47 activity is installed to cleaning roller 48's opposite side, driving motor is all installed to the one end that material loading roller and unloading roller stretched out clearance mounting panel 47, cleaning cloth belt 63 twines on material loading roller and unloading roller, the feed liquor pipe that cup joints with cleaning roller 48 is fixed is installed to the one end of holding tank 61.
Example two:
the lifting unit 10 comprises a driven plate 12 which is connected with the inner side wall of the housing 91 in a sliding mode and moves along the horizontal direction, a placing plate 11 which is arranged along the horizontal direction is installed at the bottom of the end, far away from the pushing unit 99, of the driven plate 12, a first rack which is arranged along the length direction of the driven plate 12 is installed on one side of the driven plate 12, a first gear which is movably sleeved with the housing 91 is meshed on one side of the first rack, a second gear which is movably sleeved with the housing 91 is meshed on one side of the first gear, a second rack which is fixedly connected with the outer side wall of the push-pull plate 71 is meshed on the second gear, and a discharging channel 13 penetrates through the lower portion, close to the partition plate 2, of one side of the housing 91.
Example three:
Example four:
a driving plate with an L-shaped structure is mounted on one side of the cutter mounting plate 41, which is far away from the cutter 411, and a second push rod motor fixedly connected with the box body 1 is mounted at the top of the driving plate.
Example five:
the docking unit comprises an adapter ring 51 fixedly connected to the mounting plate 21 of the movable clamping unit 95, the adapter ring 51 is coaxially arranged with the driving shaft 93, an adjusting plate 52 with a circular arc structure is fixedly connected to an inner ring of the adapter ring 51, a retaining plate 54 with a circular arc structure and fixedly connected with the adapter ring 51 is installed on one side of the adjusting plate 52, a rotating plate 53 with a long strip structure and fixedly connected with the driving shaft 93 is installed on an inner concave surface of the adjusting plate 52, the rotating plate 53 is arranged along the length direction of the driving shaft 93, a clamping groove and a pushing groove are formed in one side, away from the driving shaft 93, of the rotating plate 53, the clamping groove is horizontally arranged and equidistantly distributed along the length direction of the rotating plate 53, the pushing groove is obliquely arranged and equidistantly distributed along the length direction of the rotating plate 53, the clamping groove and the pushing groove are communicated in a staggered position, an internal thread connected with the pushing groove in a threaded mode is formed in the inner concave surface of the adjusting plate 52, and a butt joint groove is formed in the inner concave surface of the retaining plate 54.
The working principle is as follows: when a sample is cut, the second push rod motor on the cutter mounting plate 41 is started to push the driving plate to move, then the cutter mounting plate 41 is moved, the cutter mounting plate 41 drives the cutter 411 to cut the sample, at the moment, the cutter mounting plate 41 drives the extrusion plate 42 on the cutter mounting plate to move together, the extrusion plate 42 pushes the front end abutting rod 45 on the extrusion plate to the direction away from each other, so that the push ring 44 moves along with the extrusion plate, then the push ring 44 drives the cross rod 412 to move, so that the cleaning mounting plate 47 moves to the position away from each other, the two groups of cleaning rollers 48 also move to the position away from each other, when the cutting is completed, the second push rod motor is started to move the driving plate to the initial position, at the moment, under the action of the second spring 410, the two groups of cleaning mounting plates 47 move to the position away from each other, so that the two groups of cleaning rollers 48 move to the positions close to each other, and the cleaning cloth belts 63 on the cleaning rollers 48 are in contact with the surfaces of the cutter 411, then cleaning the foreign matters on the cutting knife 411 along with the movement of the cleaning cloth belt 48;
when placing a sample, firstly, a pushing unit 99 of a push rod motor is adopted to start to push the integral feeding conveying mechanism 9 out of the top of the box body 1, then a first push rod motor 72 is adopted to start to push a push-pull plate 71 towards the direction of the partition board 2, at this time, the push-pull plate 71 pushes the open-close plates 28 on the fixed clamping unit 94 and the movable clamping unit 95 towards the direction of the partition board 2, at this time, the frame 27 and the push plate 25 both move towards the direction of the partition board 2, then the push plate 25 pushes the pull rods 24 towards the direction of separating from each other, the two groups of movable plates 22 move towards the direction of separating from each other, the two groups of clamping plates 23 move towards the direction of separating from each other, simultaneously, along with the movement of the push-pull plate 71, the second rack is driven to move, then the first gear and the second gear move, so that the driven plate 12 on the first rack and the placing plate 11 move towards the direction of the partition board 2 along with the first gear, and the sample is placed on the top of the placing plate 11 before clamping, the sample clamping device is arranged between the two groups of clamping plates 23, the first push rod motor 72 is started during clamping to drive the push-pull plate 71 to move in the direction away from the partition plate 2, the opposite steps are carried out, the push-pull plate 71 pulls the opening-closing plate 28 in the direction away from the partition plate 2, so that the clamping plates 23 clamp the sample, and then the pushing unit 99 is started to convey the cover 91 to the interior of the box body 1;
when the sample is cut, the sample needs to be conveyed downwards, when the sample is conveyed, firstly, the first push rod motor 72 is started, the first cut-off plate 28 is pushed to the direction of the partition plate 2 to half of the whole stroke of the first cut-off plate, at the moment, the placing plate 11 only moves to the direction of the partition plate 2 to half of the stroke of the first cut-off plate, the placing plate 11 does not block the discharge channel 13 at the bottom of the housing 91, so that the cut sample conveniently drops downwards, then, the motor positioned at the top of the driving shaft 93 is started to rotate the driving shaft 93, and then the driving shaft 93 drives the adjusting unit 97 to move under the action of the switching unit 95;
at this time, the first projection 33 and the second projection on the adjusting unit 97 rotate along with the rotating shaft 31 to drive the frame 27 to move back and forth, and the clamping plate 23 is installed to clamp and open the gap between the fixed clamping unit 94 and the movable clamping unit 95 to clamp the sample;
meanwhile, when the movable clamping unit 95 clamps a sample, the rotating plate 53 rotates along with the driving shaft 93, at the moment, the rotating plate 53 moves from the position of the retaining plate 54 to the direction of the adjusting plate 52, the adapter ring 51 moves downwards under the action of the pushing groove and the internal thread when the rotating plate 53 is in butt joint with the adjusting plate 53, and the clamping groove and the butt joint groove are in butt joint when the rotating plate 53 is in butt joint with the retaining plate 54, so that the rotating plate 53 is prevented from falling downwards, the movable clamping unit 95 can push the sample downwards when clamping, and feeding and cutting of the sample are facilitated;
the cut samples fall downwards into a tray in a containing box on the sample conveying mechanism 7 and are discharged from the discharge channel 6;
this design has realized the transport operation of sample, can utilize intermittent type centre gripping mode to carry out the pay-off in the cutting, makes things convenient for the continuous section of sample to handle, can clear up the cutter simultaneously in the cutting, avoids the remaining material of cutter to lead to the fact the destruction to the piece in the cutting, improves sliced quality, avoids the cutter to pollute the section simultaneously in the cutting.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations and positional relationships based on those shown in the drawings, and are used only for convenience of description and simplicity of description, and do not indicate or imply that the equipment or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be considered as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (10)
1. The pathological section device based on the tumor molecular mechanism research experiment comprises a box body (1) and is characterized in that a partition plate (2) arranged in the vertical direction is installed inside the box body (1), a cutter channel (3) penetrates through the partition plate (2), a cutting and cleaning mechanism (4) is installed at one end of the cutter channel (3), a supporting plate (5) fixedly connected with the inner side wall of the box body (1) and arranged in the horizontal direction is installed above the other end of the cutter channel (3), a feeding conveying mechanism (9) is installed at the top of the supporting plate (5), a discharging channel (6) penetrating through the box body (1) is formed below one side, far away from the partition plate (2), of the supporting plate (5), and a sample conveying mechanism (7) is installed inside the discharging channel (6);
the feeding conveying mechanism (9) comprises a cover shell (91) fixedly connected with a supporting plate (5), the opening of the cover shell (91) is positioned on one side, close to the partition plate (2), of the cover shell (91), a driving shaft (93) arranged in the vertical direction is installed inside the cover shell (91), a fixed clamping unit (94) is movably sleeved on the outer ring of the driving shaft (93), a movable clamping unit (95) which is arranged in parallel with the fixed clamping unit (94) and connected with the driving shaft (93) is installed at the top of the fixed clamping unit (94), a butt joint unit connected with the driving shaft (93) is installed on the movable clamping unit (95), a switching unit (96) connected with the driving shaft (93) is installed at the top of the movable clamping unit (95), the switching unit (96) is connected with an adjusting unit (97) arranged in parallel with the driving shaft (93), and the adjusting unit (97) is positioned on one side, far away from the partition plate (2), of the driving shaft (93), one side of adjusting unit (97) keeping away from driving shaft (93) is installed and is opened and shut unit (98) be connected with fixed clamping unit (94) and activity clamping unit (95), the opposite side of opening and shutting unit (98) is installed and is followed promotion unit (99) that vertical direction set up, the top output of promotion unit (99) and housing (91) top inside wall rigid coupling, promote unit (99) bottom and layer board (5) rigid coupling, the bottom of fixed clamping unit (94) is installed and is lifted unit (10) with opening and shutting unit (98) connection.
2. The pathological section device based on tumor molecular mechanism research experiment of claim 1, wherein the fixed clamping unit (94) comprises a mounting plate (21) with a hollow structure, a guide plate (26) is installed inside the mounting plate (21), the guide plate (26) is connected with movable plates (22) symmetrically arranged along the driving shaft (93) through slide rail sliders, one ends of the movable plates (22) extending out of the mounting plate (21) are fixedly connected with clamping plates (23) with circular arc structures, the guide plate (26) is located on one side of the driving shaft (93) far away from the partition plate (2), one sides of the guide plates (26) far away from the driving shaft (93) are respectively provided with pull rods (24) hinged with the end portions of the movable plates (22), one ends of the two groups of pull rods (24) far away from the movable plates (22) are hinged with push plates (25) with the same L-shaped structure, and the push plates (25) are movably sleeved with the mounting plate (21), the fixed connection has spring one between push pedal (25) and deflector (26), the one end rigid coupling that push pedal (25) stretched out mounting panel (21) has frame (27) of rectangle structure, and adjusting element (97) are located the inner circle of frame (27), the one end rigid coupling that push pedal (25) was kept away from in frame (27) has open-close plate (28) of T type structure, fixed clamping unit (94) are unanimous with the structure of activity clamping unit (95), mounting panel (21) and driving shaft (93) activity of fixed clamping unit (94) are cup jointed, mounting panel (21) and driving shaft (93) screw thread of activity clamping unit (95) are cup jointed.
3. The pathological section device based on tumor molecular mechanism research experiment of claim 1, wherein the switching unit (96) adopts any one of belt pulley or chain wheel chain.
4. The pathological section device based on tumor molecular mechanism research experiment of claim 1, wherein the adjusting unit (97) comprises a rotating shaft (31) connected with the switching unit (96), a first sleeve (32) fixedly sleeved on the outer ring of the rotating shaft (31) and arranged along the length direction of the rotating shaft, a first projection (33) fixedly arranged along the length direction of the first sleeve is fixedly connected to the outer ring of the first sleeve (32), a second sleeve fixedly sleeved with the outer ring of the rotating shaft (31) is installed at the bottom of the first sleeve (32), a second projection arranged along the length direction of the second sleeve is fixedly connected to the outer ring of the second sleeve, and the second projection and the first projection (33) are symmetrically distributed along the axis of the rotating shaft (31).
5. The pathological section device based on tumor molecular mechanism research experiment of claim 1, wherein the opening and closing unit (98) comprises a push-pull plate (71) with a U-shaped structure, the end of the opening and closing plate (28) extending into the push-pull plate (71) is slidably connected with the adjacent inner side wall of the push-pull plate (71), the two ends of the push-pull plate (71) close to the opening of the frame (27) are fixedly connected with a baffle, and the end of the push-pull plate (71) far away from the frame (27) is fixedly connected with a push rod motor I (72) fixedly connected with the inner side wall of the housing (91).
6. The pathological section device based on tumor molecular mechanism research experiment as claimed in claim 1, wherein the cutting and cleaning mechanism (4) comprises a cutter mounting plate (41) disposed along the horizontal direction, the cutter (411) is mounted at the end of the cutter mounting plate (41) close to the cutter channel (3), both sides of the end of the cutter mounting plate (41) far away from the cutter (411) are respectively mounted with a pressing plate (42) having a trapezoid structure, the end of the pressing plate (42) far away from the cutter mounting plate (41) is fixedly connected with a butt plate (43), both ends of the two sets of butt plates (43) far away from each other are respectively mounted with a pushing ring (44), both sides of the two sets of pushing rings (44) close to each other are respectively mounted with a front butt rod (45) and a rear butt rod (46), the front butt rod (45) and the rear butt rod (46) are located at both sides of the butt plate (43), and the front butt rod (45) is located at the side of the butt plate (43) close to the cutter (411), horizontal pole (412) that the inner circle of propelling movement ring (44) all slided to cup joint and set up along the horizontal direction, the equal rigid coupling in one side that two sets of horizontal poles (412) are close to baffle (2) have with box (1) inside wall sliding connection and along clearance mounting panel (47) that vertical direction removed, the equal rigid coupling in one side that two sets of clearance mounting panels (47) are close to each other has cleaning roller (48), roof (49) with box (1) rigid coupling are all installed to one side that two sets of clearance mounting panels (47) kept away from each other, install spring two (410) between roof (49) and the clearance mounting panel (47).
7. The pathological section device of claim 6, its characterized in that, holding tank (61) that sets up along its length direction are seted up to the one side that cleaning roller (48) are close to each other, shrouding (62) of loop configuration are installed to the opening part of holding tank (61), shrouding (62) run through have the orifice that sets up along its length direction, washing strap (63) are installed to the evagination face of shrouding (62), the material loading roller that cup joints with clearance mounting panel (47) activity is installed to one side of cleaning roller (48), the unloading roller that cup joints with clearance mounting panel (47) activity is installed to the opposite side of cleaning roller (48), driving motor is all installed to the one end that material loading roller and unloading roller stretched out clearance mounting panel (47), it twines on material loading roller and unloading roller to wash strap (63), the feed liquor pipe that cup joints with cleaning roller (48) is fixed is installed to the one end of holding tank (61).
8. The pathological section device based on tumor molecular mechanism research experiment of claim 6, characterized in that, the lifting unit (10) includes a driven plate (12) slidably connected with the inner side wall of the housing (91) and moving along the horizontal direction, a placing plate (11) horizontally disposed is installed at the bottom of one end of the driven plate (12) far away from the pushing unit (99), a first rack bar horizontally disposed is installed at one side of the driven plate (12), a first gear movably sleeved with the housing (91) is engaged at one side of the first rack bar, a second gear movably sleeved with the housing (91) is engaged at one side of the first gear, a second rack bar fixedly connected with the outer side wall of the push-pull plate (71) is engaged at the second gear, and a discharging channel (13) penetrates through the lower portion of one side of the housing (91) close to the partition plate (2).
9. The pathological section device based on tumour molecular mechanism research experiment of claim 1, characterized in that, sample conveying mechanism (7) include with layer board (5) bottom rigid coupling extend the board, and extend the board from discharge channel (6) and stretch out to the inside of box (1), the chain of loop configuration is installed to the bottom of extend board, the inner circle of chain one is connected with sprocket one, the fixed dwang that cup joints with extend board activity of cup jointing of inner circle of chain one, the motor two with box (1) inside wall rigid coupling is installed to the bottom of dwang, the outer lane rigid coupling of chain one has the connecting plate that sets up along its length direction, the top rigid coupling of connecting plate has the top to be provided with the open-ended and holds the box.
10. The pathological section device based on tumor molecular mechanism research experiment of claim 6, wherein the cutter mounting plate (41) is provided with a driving plate of L-shaped structure at the side far away from the cutter (411), and the top of the driving plate is provided with a second push rod motor fixedly connected with the box body (1).
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Cited By (1)
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CN113985595A (en) * | 2021-10-25 | 2022-01-28 | 山东大学齐鲁医院 | Sample irradiation device |
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