CN113413345A - 一种牡丹润颜滋养精华液及其制备方法 - Google Patents
一种牡丹润颜滋养精华液及其制备方法 Download PDFInfo
- Publication number
- CN113413345A CN113413345A CN202110841282.8A CN202110841282A CN113413345A CN 113413345 A CN113413345 A CN 113413345A CN 202110841282 A CN202110841282 A CN 202110841282A CN 113413345 A CN113413345 A CN 113413345A
- Authority
- CN
- China
- Prior art keywords
- parts
- skin conditioner
- peony
- skin
- essence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000006484 Paeonia officinalis Nutrition 0.000 title claims abstract description 55
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 244000170916 Paeonia officinalis Species 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 63
- 241000736199 Paeonia Species 0.000 claims abstract description 54
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 48
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 39
- -1 polydimethylsiloxane Polymers 0.000 claims abstract description 34
- 241001673954 Magnolia sieboldii Species 0.000 claims abstract description 20
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 20
- 229940015975 1,2-hexanediol Drugs 0.000 claims abstract description 16
- 229920001577 copolymer Polymers 0.000 claims abstract description 16
- 239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 16
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 16
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 15
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 15
- ZGSCRDSBTNQPMS-UJURSFKZSA-N 3-O-Ethylascorbic acid Chemical compound CCOC1=C(O)C(=O)O[C@@H]1[C@@H](O)CO ZGSCRDSBTNQPMS-UJURSFKZSA-N 0.000 claims abstract description 13
- 229940120145 3-o-ethylascorbic acid Drugs 0.000 claims abstract description 13
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 claims abstract description 13
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 13
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims abstract description 13
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 13
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims abstract description 13
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims abstract description 13
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims abstract description 13
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 13
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 13
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims abstract description 13
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229960003237 betaine Drugs 0.000 claims abstract description 13
- 229960001631 carbomer Drugs 0.000 claims abstract description 13
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 claims abstract description 13
- 229930182478 glucoside Natural products 0.000 claims abstract description 13
- 229940101267 panthenol Drugs 0.000 claims abstract description 13
- 235000020957 pantothenol Nutrition 0.000 claims abstract description 13
- 239000011619 pantothenol Substances 0.000 claims abstract description 13
- 229940078492 ppg-17 Drugs 0.000 claims abstract description 13
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 13
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 13
- 239000000230 xanthan gum Substances 0.000 claims abstract description 13
- 229920001285 xanthan gum Polymers 0.000 claims abstract description 13
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 13
- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 13
- FDPIMTJIUBPUKL-UHFFFAOYSA-N pentan-3-one Chemical compound CCC(=O)CC FDPIMTJIUBPUKL-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 7
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 18
- 229960004063 propylene glycol Drugs 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 8
- 230000001804 emulsifying effect Effects 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- BANXPJUEBPWEOT-UHFFFAOYSA-N 2-methyl-Pentadecane Chemical compound CCCCCCCCCCCCCC(C)C BANXPJUEBPWEOT-UHFFFAOYSA-N 0.000 claims description 6
- UILPJVPSNHJFIK-UHFFFAOYSA-N Paeonol Chemical compound COC1=CC=C(C(C)=O)C(O)=C1 UILPJVPSNHJFIK-UHFFFAOYSA-N 0.000 claims description 6
- 239000004698 Polyethylene Substances 0.000 claims description 6
- 229920000573 polyethylene Polymers 0.000 claims description 6
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 3
- 229940043268 2,2,4,4,6,8,8-heptamethylnonane Drugs 0.000 claims description 3
- ILCOCZBHMDEIAI-UHFFFAOYSA-N 2-(2-octadecoxyethoxy)ethanol Chemical compound CCCCCCCCCCCCCCCCCCOCCOCCO ILCOCZBHMDEIAI-UHFFFAOYSA-N 0.000 claims description 3
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims description 3
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 claims description 3
- ICIDSZQHPUZUHC-UHFFFAOYSA-N 2-octadecoxyethanol Chemical compound CCCCCCCCCCCCCCCCCCOCCO ICIDSZQHPUZUHC-UHFFFAOYSA-N 0.000 claims description 3
- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 claims description 3
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 claims description 3
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 claims description 3
- 150000001720 carbohydrates Chemical class 0.000 claims description 3
- YLTGFGDODHXMFB-UHFFFAOYSA-N isoacetovanillon Natural products COC1=CC=C(C(C)=O)C=C1O YLTGFGDODHXMFB-UHFFFAOYSA-N 0.000 claims description 3
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 claims description 3
- KUVMKLCGXIYSNH-UHFFFAOYSA-N isopentadecane Natural products CCCCCCCCCCCCC(C)C KUVMKLCGXIYSNH-UHFFFAOYSA-N 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- MLIBGOFSXXWRIY-UHFFFAOYSA-N paeonol Natural products COC1=CC=C(O)C(C(C)=O)=C1 MLIBGOFSXXWRIY-UHFFFAOYSA-N 0.000 claims description 3
- 229920003217 poly(methylsilsesquioxane) Polymers 0.000 claims description 3
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims description 3
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 3
- 229940068968 polysorbate 80 Drugs 0.000 claims description 3
- 229920000053 polysorbate 80 Polymers 0.000 claims description 3
- 229940047670 sodium acrylate Drugs 0.000 claims description 3
- 239000001509 sodium citrate Substances 0.000 claims description 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 3
- 229950004959 sorbitan oleate Drugs 0.000 claims description 3
- 229940098760 steareth-2 Drugs 0.000 claims description 3
- 229940100458 steareth-21 Drugs 0.000 claims description 3
- 241000628997 Flos Species 0.000 claims description 2
- 238000007599 discharging Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 238000007689 inspection Methods 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 238000004321 preservation Methods 0.000 claims description 2
- 238000005070 sampling Methods 0.000 claims description 2
- 210000003491 skin Anatomy 0.000 description 101
- 235000011187 glycerol Nutrition 0.000 description 18
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 11
- 230000000694 effects Effects 0.000 description 7
- 206010000496 acne Diseases 0.000 description 6
- 230000002708 enhancing effect Effects 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 208000002874 Acne Vulgaris Diseases 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 4
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 4
- 238000005282 brightening Methods 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 238000009499 grossing Methods 0.000 description 4
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 4
- 210000000434 stratum corneum Anatomy 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 230000004888 barrier function Effects 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000003750 conditioning effect Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 210000000245 forearm Anatomy 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 210000002510 keratinocyte Anatomy 0.000 description 3
- 210000002966 serum Anatomy 0.000 description 3
- 230000009759 skin aging Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 206010067484 Adverse reaction Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010040844 Skin exfoliation Diseases 0.000 description 2
- 230000006838 adverse reaction Effects 0.000 description 2
- 230000032683 aging Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000001153 anti-wrinkle effect Effects 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000035618 desquamation Effects 0.000 description 2
- 230000003467 diminishing effect Effects 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 210000002752 melanocyte Anatomy 0.000 description 2
- 210000002780 melanosome Anatomy 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000008439 repair process Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000001502 supplementing effect Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 229940084032 paeonia lactiflora root extract Drugs 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
本发明公开了一种牡丹润颜滋养精华液及其制备方法,包括以下原料及重量份数:纯水65‑80份、牡丹花水2‑14份、甘油2‑11份、丁二醇3‑9份、透明质酸钠0.05‑0.3份、丙二醇0.5‑1.5份、1,2‑己二醇0.2‑0.8份、EDTA二钠0.01‑0.09份、卡波姆0.1‑0.7份、黄原胶0.02‑0.2份、氨甲基丙醇0.1‑0.5份、3‑邻‑乙基抗坏血酸0.001‑0.006份、聚乙二醇‑81‑3份、PEG/PPG‑17/6共聚物1‑2份、烟酰胺2‑8份、甜菜碱0.6‑1份、甘草酸二钾0.1‑0.8份、双‑PEG‑15甲基醚聚二甲基硅氧烷0.2‑0.8份、对羟基苯乙酮0.11‑0.99份、甘油葡糖苷0.23‑0.78份、泛醇0.2‑0.7份、牡丹籽油0.001‑0.003份、天女木兰提取物0.001‑0.004份、皮肤调理剂一0.3‑1.3份、皮肤调理剂二0.2‑1份、皮肤调理剂三0.1‑0.8份、皮肤调理剂四2‑5份、皮肤调理剂五0.01‑0.8份和香精0.02‑0.07份。
Description
技术领域
本发明属于化妆品技术领域,尤其涉及一种牡丹润颜滋养精华液及其制备方法。
背景技术
随着年龄的增长,人体角质层的更新率变得越来越慢,同时角质细胞的脂质合成能力下降,或表皮中的细胞***、生长和分化效率变低。由于皮肤缺少保湿因子和脂质,角质层屏障功能日趋下降。当角质层水分含量低于10%时,皮肤就会显得干燥、失去弹性、起皱,进而加速皮肤老化。另一方面,不当的生活方式如过度的洗脸或洗澡以及不良的环境因素如干燥的空气或污染物、以及固有的疾病如过敏或老年皮肤疾病也会使角质层丧失其原本的功能。皮肤遭受炎热、寒冷、风吹、清洁剂和紫外线辐射等侵害,表层会变得更加干燥。水是皮肤的重要组成成分,含水量高的皮肤,表皮细胞新陈代谢正常,表皮能量充足,呈现出稚嫩、丰满、亮泽与柔软的外观。比如,婴幼儿皮肤由于其含水量高就显得细嫩光泽,而老年人皮肤因为含水量较低,所以显得干燥和萎瘪,容易脱屑,甚至于发生皱纹。因此,如何保持皮肤的水分,减少水分散失在化妆品研发中十分重要。
现有的植物护肤精华液的中,不含有牡丹籽油的加入,使得精华液对于皮肤的修复和防护持续时间短,对使用者的护肤使用效果不佳。
有鉴于此,特提出本发明。
发明内容
针对现有技术中存在的问题,本发明的目的是提供一种牡丹润颜滋养精华液及其制备方法,经合理配伍,科学配比而成,天然植物中含有不同的功能性成分,这些功能因子的性质和功效各有不同,会产生一定的协同作用,调理油痘肌功能,补充肌肤养分及水分,改善肌肤的光泽度,细腻度和紧致度。
为了实现上述目的,本发明提供的一种牡丹润颜滋养精华液及其制备方法,包括以下原料及重量份数:纯水65-80份、牡丹花水2-14份、甘油2-11份、丁二醇3-9份、透明质酸钠0.05-0.3份、丙二醇0.5-1.5份、1,2-己二醇0.2-0.8份、EDTA 二钠0.01-0.09份、卡波姆0.1-0.7份、黄原胶0.02-0.2份、氨甲基丙醇0.1-0.5份、3-邻-乙基抗坏血酸0.001-0.006份、聚乙二醇-81-3份、PEG/PPG-17/6 共聚物1-2份、烟酰胺2-8份、甜菜碱0.6-1份、甘草酸二钾0.1-0.8份、双-PEG-15 甲基醚聚二甲基硅氧烷0.2-0.8份、对羟基苯乙酮0.11-0.99份、甘油葡糖苷0.23-0.78份、泛醇0.2-0.7份、牡丹籽油0.001-0.003份、天女木兰提取物0.001-0.004份、皮肤调理剂一0.3-1.3份、皮肤调理剂二0.2-1份、皮肤调理剂三0.1-0.8份、皮肤调理剂四2-5份、皮肤调理剂五0.01-0.8份和香精0.02-0.07份。
优选地,各所述组分的组分含量按重量份计为:纯水70.757份、甘油5份、丁二醇5份、牡丹花水3份、透明质酸钠0.1份、丙二醇0.9份、1,2-己二醇0.45份、EDTA 二钠0.02份、卡波姆0.2份、黄原胶0.08份、氨甲基丙醇0.1份、3-邻-乙基抗坏血酸0.001份、聚乙二醇-83份、PEG/PPG-17/6 共聚物2份、烟酰胺2份、甜菜碱1份、甘草酸二钾0.2份、双-PEG-15 甲基醚聚二甲基硅氧烷0.5份、对羟基苯乙酮0.45份、甘油葡糖苷0.6份、泛醇0.5份、牡丹籽油0.001份、天女木兰提取物0.001份、皮肤调理剂一0.8份、皮肤调理剂二0.2份、皮肤调理剂三0.5份、皮肤调理剂四2份、皮肤调理剂五0.6份和香精0.04份;
优选地,所述皮肤调理剂一由聚甲基硅倍半氧烷、聚二甲基硅氧烷、异十二烷、PEG-40 硬脂酸酯、鲸蜡硬脂基聚甲基硅氧烷、硬脂醇聚醚-2和硬脂醇聚醚-21组成;
优选地,所述皮肤调理剂二由丙烯酸钠/丙烯酰二甲基牛磺酸钠共聚物、水、异十六烷、聚山梨醇酯-80和山梨坦油酸酯组成;
优选地,所述皮肤调理剂三由水、丁二醇、1,2-己二醇和芍药根提取物组成;
优选地,所述皮肤调理剂四由水、丹皮酚和牡丹根提取物组成;
优选地,所述皮肤调理剂五由水、糖类同分异构体、柠檬酸和柠檬酸钠组成。
本发明提供的一种牡丹润颜滋养精华液及其制备方法,具有如下有益效果:
本发明采用特定的科学配比的甘油、丁二醇、透明质酸钠、丙二醇、1,2-己二醇、EDTA 二钠、卡波姆、黄原胶、氨甲基丙醇、3-邻-乙基抗坏血酸、聚乙二醇-8、PEG/PPG-17/6共聚物、烟酰胺、甜菜碱、甘草酸二钾、双-PEG-15 甲基醚聚二甲基硅氧烷、对羟基苯乙酮、甘油葡糖苷、泛醇、牡丹花水、牡丹籽油、天女木兰提取物、皮肤调理剂一、皮肤调理剂二、皮肤调理剂三、皮肤调理剂四、皮肤调理剂五和香精在抗菌消炎,调理油痘肌功能,补充肌肤养分及水分,改善肌肤的光泽度,细腻度,紧致度的效果上相互促进,牡丹籽油柔和修护,抚润细纹,嫩滑细腻,打造滢亮水光肌,提亮均匀肤色,增强屏障修护力,改良肌肤因受外界刺激而造成的不良反应,增强肌肤抗皱能力,避免皮肤老化速度加快,促进皮肤光滑均匀,抗衰除皱。天女木兰花修复薄弱细胞,消解红血丝,增强肌肤耐受性,让肌肤远离刺痛、脱皮、红肿、粗糙等问题,从根源处改善肌肤过敏症状。天女木兰花蕴含的天然抑菌因子,可以让皮肤远离粉刺、痤疮、青春痘等问题。天女木兰独特的天然消炎成分,持续消除肌肤炎症,修复受损细胞,还原肌肤活能,重塑丝滑肤感。天女木兰花的花朵和树枝上的厚朴酚,可以抑制黑素体从黑素细胞转运到角质细胞以及抑制黑色素的形成,也具有抗氧化功效,是一种原生态美白的植物。
具体实施方式
下面结合具体实施例对本发明做进一步说明,以助于理解本发明的内容。
本发明提供的一种牡丹润颜滋养精华液,包括以下原料及重量份数:纯水65-80份、牡丹花水2-14份、甘油2-11份、丁二醇3-9份、透明质酸钠0.05-0.3份、丙二醇0.5-1.5份、1,2-己二醇0.2-0.8份、EDTA 二钠0.01-0.09份、卡波姆0.1-0.7份、黄原胶0.02-0.2份、氨甲基丙醇0.1-0.5份、3-邻-乙基抗坏血酸0.001-0.006份、聚乙二醇-81-3份、PEG/PPG-17/6 共聚物1-2份、烟酰胺2-8份、甜菜碱0.6-1份、甘草酸二钾0.1-0.8份、双-PEG-15 甲基醚聚二甲基硅氧烷0.2-0.8份、对羟基苯乙酮0.11-0.99份、甘油葡糖苷0.23-0.78份、泛醇0.2-0.7份、牡丹籽油0.001-0.003份、天女木兰提取物0.001-0.004份、皮肤调理剂一0.3-1.3份、皮肤调理剂二0.2-1份、皮肤调理剂三0.1-0.8份、皮肤调理剂四2-5份、皮肤调理剂五0.01-0.8份和香精0.02-0.07份。
其中,皮肤调理剂一由聚甲基硅倍半氧烷、聚二甲基硅氧烷、异十二烷、PEG-40 硬脂酸酯、鲸蜡硬脂基聚甲基硅氧烷、硬脂醇聚醚-2和硬脂醇聚醚-21组成;皮肤调理剂二由丙烯酸钠/丙烯酰二甲基牛磺酸钠共聚物、水、异十六烷、聚山梨醇酯-80和山梨坦油酸酯组成;皮肤调理剂三由水、丁二醇、1,2-己二醇和芍药根提取物组成;皮肤调理剂四由水、丹皮酚和牡丹根提取物组成;皮肤调理剂五由水、糖类同分异构体、柠檬酸和柠檬酸钠组成。
本发明提供的一种牡丹润颜滋养精华液的制备方法,包括如下步骤:
1、预先把丁二醇、甘油、聚乙二醇-8、PEG/PPG-17/6 共聚物和部分纯水加入乳化锅分散卡波姆、黄原胶和透明质酸钠,开均质500-1000r/min分散;分散均匀后加入EDTA 二钠、烟酰胺、甜菜碱、甘草酸二钾和双-PEG-15 甲基醚聚二甲基硅氧烷,按照30-35r/min的转速搅拌加热至85℃,保温20-30分钟再均质3分钟至完全溶解无颗粒;
2、开始降温,降温至65-70℃,然后加入氨甲基丙醇,搅拌15-20分钟至完全均匀无颗粒(30-35r/min);
3、降温至55-60℃,然后将皮肤调理剂一和皮肤调理剂二依次加入乳化锅,搅拌至完全均匀(30-35r/min);
4、降温至40-45℃,将丙二醇、对羟基苯乙酮和1,2-己二醇混合均匀,加热至50-55℃溶解无颗粒,然后加入乳化锅,搅拌至完全均匀无颗粒(30-35r/min);
5、降温至38-40℃以下,将牡丹花水、皮肤调理剂三、皮肤调理剂四、香精、甘油葡糖苷、泛醇、皮肤调理剂五、牡丹籽油、3-邻-乙基抗坏血酸和天女木兰提取物依次加入乳化锅,搅拌10-15分钟至搅拌均匀(30-30r/min);
6、取样送检,检验合格后,100目滤网过滤出料。
实施例1:
本发明提供的一种牡丹润颜滋养精华液及其制备方法,包括以下原料及重量份数:纯水70.757份、甘油5份、丁二醇5份、透明质酸钠0.1份、丙二醇0.9份、1,2-己二醇0.45份、EDTA 二钠0.02份、卡波姆0.2份、黄原胶0.08份、氨甲基丙醇0.1份、3-邻-乙基抗坏血酸0.001份、聚乙二醇-83份、PEG/PPG-17/6 共聚物2份、烟酰胺2份、甜菜碱1份、甘草酸二钾0.2份、双-PEG-15 甲基醚聚二甲基硅氧烷0.5份、对羟基苯乙酮0.45份、甘油葡糖苷0.6份、泛醇0.5份、牡丹花水3份、牡丹籽油0.001份、天女木兰提取物0.001份、皮肤调理剂一0.8份、皮肤调理剂二0.2份、皮肤调理剂三0.5份、皮肤调理剂四2份、皮肤调理剂五0.6份和香精0.04份。
选择实施例1中提供的精华液进行临床实验:
该实验包括22位志愿者,年龄在21-45周岁,统一清洗双手前臂内侧,做好测量标记,产品涂抹区和空白对照区随机分布于左右手臂标定区域,先测量各区域的初始值,再将测试样品按规定量单次涂布。在设定时间点使用皮肤水分测试仪进行产品区域和对照区域的测量,每个区域平行测定5次,取平均值记录。
精华液使用前、使用后1小时和使用后4小时的皮肤角质层含水量变化率分别为0%、81%和40%。结果显示,精华液使皮肤角质层含水量在1小时后具有很大的提高,并且在使用后4小时能得到较好的维持。
实施例2:
本发明提供的一种牡丹润颜滋养精华液及其制备方法,包括以下原料及重量份数:纯水77.5份、甘油7份、丁二醇6份、透明质酸钠0.2份、丙二醇0.5份、1,2-己二醇0.2份、EDTA 二钠0.09份、卡波姆0.5份、黄原胶0.05份、氨甲基丙醇0.2份、3-邻-乙基抗坏血酸0.003份、聚乙二醇-81份、PEG/PPG-17/6 共聚物1份、烟酰胺5份、甜菜碱0.7份、甘草酸二钾0.3份、双-PEG-15 甲基醚聚二甲基硅氧烷0.8份、对羟基苯乙酮0.11份、甘油葡糖苷0.4份、泛醇0.7份、牡丹花水10份、牡丹籽油0.002份、天女木兰提取物0.004份、皮肤调理剂一0.1份、皮肤调理剂二0.5份、皮肤调理剂三0.1份、皮肤调理剂四4份、皮肤调理剂五0.1份和香精0.07份。
选择实施例2中提供的精华液进行临床实验:
该实验包括22位志愿者,年龄在21-45周岁,统一清洗双手前臂内侧,做好测量标记,产品涂抹区和空白对照区随机分布于左右手臂标定区域,先测量各区域的初始值,再将测试样品按规定量单次涂布。在设定时间点使用皮肤水分测试仪进行产品区域和对照区域的测量,每个区域平行测定5次,取平均值记录。
精华液使用前、使用后1小时和使用后4小时的皮肤角质层含水量变化率分别为0%、77%和34%。结果显示,精华液使皮肤角质层含水量在1小时后具有很大的提高,并且在使用后4小时能得到较好的维持。
实施例3:
本发明提供的一种牡丹润颜滋养精华液及其制备方法,包括以下原料及重量份数:纯水65.9份、甘油2份、丁二醇3份、透明质酸钠0.3份、丙二醇1.5份、1,2-己二醇0.8份、EDTA 二钠0.06份、卡波姆0.4份、黄原胶0.2份、氨甲基丙醇0.5份、3-邻-乙基抗坏血酸0.006份、聚乙二醇-82份、PEG/PPG-17/6 共聚物1.5份、烟酰胺8份、甜菜碱0.8份、甘草酸二钾0.8份、双-PEG-15 甲基醚聚二甲基硅氧烷0.2份、对羟基苯乙酮0.86份、甘油葡糖苷0.2份、泛醇0.2份、牡丹花水8份、牡丹籽油0.003份、天女木兰提取物0.004份、皮肤调理剂一0.9份、皮肤调理剂二0.8份、皮肤调理剂三0.7份、皮肤调理剂四5份、皮肤调理剂五0.8份和香精0.02份。
选择实施例3中提供的精华液进行临床实验:
该实验包括22位志愿者,年龄在21-45周岁,统一清洗双手前臂内侧,做好测量标记,产品涂抹区和空白对照区随机分布于左右手臂标定区域,先测量各区域的初始值,再将测试样品按规定量单次涂布。在设定时间点使用皮肤水分测试仪进行产品区域和对照区域的测量,每个区域平行测定5次,取平均值记录。
精华液使用前、使用后1小时和使用后4小时的皮肤角质层含水量变化率分别为0%、79%和35%。结果显示,精华液使皮肤角质层含水量在1小时后具有很大的提高,并且在使用后4小时能得到较好的维持。
本发明采用特定的科学配比的甘油、丁二醇、透明质酸钠、丙二醇、1,2-己二醇、EDTA 二钠、卡波姆、黄原胶、氨甲基丙醇、3-邻-乙基抗坏血酸、聚乙二醇-8、PEG/PPG-17/6共聚物、烟酰胺、甜菜碱、甘草酸二钾、双-PEG-15 甲基醚聚二甲基硅氧烷、对羟基苯乙酮、甘油葡糖苷、泛醇、牡丹花水、牡丹籽油、天女木兰提取物、皮肤调理剂一、皮肤调理剂二、皮肤调理剂三、皮肤调理剂四、皮肤调理剂五和香精在抗菌消炎,调理油痘肌功能,补充肌肤养分及水分,改善肌肤的光泽度,细腻度和紧致度的效果上相互促进,牡丹籽油柔和修护,抚润细纹,嫩滑细腻,打造滢亮水光肌,提亮均匀肤色,增强屏障修护力,改良肌肤因受外界刺激而造成的不良反应,增强肌肤抗皱能力,避免皮肤老化速度加快,促进皮肤光滑均匀,抗衰除皱。天女木兰花修复薄弱细胞,消解红血丝,增强肌肤耐受性,让肌肤远离刺痛、脱皮、红肿、粗糙等问题,从根源处改善肌肤过敏症状。天女木兰花蕴含的天然抑菌因子,可以让皮肤远离粉刺、痤疮、青春痘等问题。天女木兰独特的天然消炎成分,持续消除肌肤炎症,修复受损细胞,还原肌肤活能,重塑丝滑肤感。天女木兰花的花朵和树枝上的厚朴酚,可以抑制黑素体从黑素细胞转运到角质细胞以及抑制黑色素的形成,也具有抗氧化功效,是一种原生态美白的植物。
本文中应用了具体个例对发明构思进行了详细阐述,以上实施例的说明只是用于帮助理解本发明的核心思想。应当指出,对于本技术领域的普通技术人员来说,在不脱离该发明构思的前提下,所做的任何显而易见的修改、等同替换或其他改进,均应包含在本发明的保护范围之内。
Claims (8)
1.一种牡丹润颜滋养精华液,其特征在于,包括以下原料及重量份数:纯水65-80份、牡丹花水2-14份、甘油2-11份、丁二醇3-9份、透明质酸钠0.05-0.3份、丙二醇0.5-1.5份、1,2-己二醇0.2-0.8份、EDTA 二钠0.01-0.09份、卡波姆0.1-0.7份、黄原胶0.02-0.2份、氨甲基丙醇0.1-0.5份、3-邻-乙基抗坏血酸0.001-0.006份、聚乙二醇-81-3份、PEG/PPG-17/6 共聚物1-2份、烟酰胺2-8份、甜菜碱0.6-1份、甘草酸二钾0.1-0.8份、双-PEG-15 甲基醚聚二甲基硅氧烷0.2-0.8份、对羟基苯乙酮0.11-0.99份、甘油葡糖苷0.23-0.78份、泛醇0.2-0.7份、牡丹籽油0.001-0.003份、天女木兰提取物0.001-0.004份、皮肤调理剂一0.3-1.3份、皮肤调理剂二0.2-1份、皮肤调理剂三0.1-0.8份、皮肤调理剂四2-5份、皮肤调理剂五0.01-0.8份和香精0.02-0.07份。
2.根据权利要求1所述的一种牡丹润颜滋养精华液,其特征在于,各所述组分的组分含量按重量份计为:纯水70.757份、甘油5份、丁二醇5份、牡丹花水3份、透明质酸钠0.1份、丙二醇0.9份、1,2-己二醇0.45份、EDTA 二钠0.02份、卡波姆0.2份、黄原胶0.08份、氨甲基丙醇0.1份、3-邻-乙基抗坏血酸0.001份、聚乙二醇-83份、PEG/PPG-17/6 共聚物2份、烟酰胺2份、甜菜碱1份、甘草酸二钾0.2份、双-PEG-15 甲基醚聚二甲基硅氧烷0.5份、对羟基苯乙酮0.45份、甘油葡糖苷0.6份、泛醇0.5份、牡丹籽油0.001份、天女木兰提取物0.001份、皮肤调理剂一0.8份、皮肤调理剂二0.2份、皮肤调理剂三0.5份、皮肤调理剂四2份、皮肤调理剂五0.6份和香精0.04份。
3.根据权利要求2所述的一种牡丹润颜滋养精华液,其特征在于,所述皮肤调理剂一由聚甲基硅倍半氧烷、聚二甲基硅氧烷、异十二烷、PEG-40 硬脂酸酯、鲸蜡硬脂基聚甲基硅氧烷、硬脂醇聚醚-2和硬脂醇聚醚-21组成。
4.根据权利要求2所述的一种牡丹润颜滋养精华液,其特征在于,所述皮肤调理剂二由丙烯酸钠/丙烯酰二甲基牛磺酸钠共聚物、水、异十六烷、聚山梨醇酯-80和山梨坦油酸酯组成。
5.根据权利要求2所述的一种牡丹润颜滋养精华液,其特征在于,所述皮肤调理剂三由水、丁二醇、1,2-己二醇和芍药根提取物组成。
6.根据权利要求2所述的一种牡丹润颜滋养精华液,其特征在于,所述皮肤调理剂四由水、丹皮酚和牡丹根提取物组成。
7.根据权利要求2所述的一种牡丹润颜滋养精华液,其特征在于,所述皮肤调理剂五由水、糖类同分异构体、柠檬酸和柠檬酸钠组成。
8.根据权利要求1所述的一种牡丹润颜滋养精华液的制备方法,其特征在于,包括如下步骤:
1、预先把丁二醇、甘油、聚乙二醇-8、PEG/PPG-17/6 共聚物和部分纯水加入乳化锅分散卡波姆、黄原胶和透明质酸钠,开均质500-1000r/min分散;分散均匀后加入EDTA 二钠、烟酰胺、甜菜碱、甘草酸二钾和双-PEG-15 甲基醚聚二甲基硅氧烷,按照30-35r/min的转速搅拌加热至85℃,保温20-30分钟再均质3分钟至完全溶解无颗粒;
2、开始降温,降温至65-70℃,然后加入氨甲基丙醇,搅拌15-20分钟至完全均匀无颗粒;
3、降温至55-60℃,然后将皮肤调理剂一和皮肤调理剂二依次加入乳化锅,搅拌至完全均匀;
4、降温至40-45℃,将丙二醇、对羟基苯乙酮和1,2-己二醇混合均匀,加热至50-55℃溶解无颗粒,然后加入乳化锅,搅拌至完全均匀无颗粒;
5、降温至38-40℃以下,将牡丹花水、皮肤调理剂三、皮肤调理剂四、香精、甘油葡糖苷、泛醇、皮肤调理剂五、牡丹籽油、3-邻-乙基抗坏血酸和天女木兰提取物依次加入乳化锅,搅拌10-15分钟至搅拌均匀;
6、取样送检,检验合格后,100目滤网过滤出料。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110841282.8A CN113413345A (zh) | 2021-07-26 | 2021-07-26 | 一种牡丹润颜滋养精华液及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202110841282.8A CN113413345A (zh) | 2021-07-26 | 2021-07-26 | 一种牡丹润颜滋养精华液及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113413345A true CN113413345A (zh) | 2021-09-21 |
Family
ID=77718319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202110841282.8A Pending CN113413345A (zh) | 2021-07-26 | 2021-07-26 | 一种牡丹润颜滋养精华液及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113413345A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115990130A (zh) * | 2023-03-25 | 2023-04-21 | 广州华厦生物制药有限公司 | 一种净颜瓷白雪肤面膜 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105560119A (zh) * | 2016-01-21 | 2016-05-11 | 定陶县地元生化制品有限公司 | 一种牡丹保湿液及其制备方法 |
CN106727127A (zh) * | 2016-12-20 | 2017-05-31 | 铜陵凤丹种植科技开发有限责任公司 | 一种含牡丹籽油的护肤精油及其制备方法 |
CN109481382A (zh) * | 2018-12-29 | 2019-03-19 | 株洲千金药业股份有限公司 | 一种含白花百合花水的保湿调理剂及其制备方法和面膜应用 |
CN109908035A (zh) * | 2019-04-25 | 2019-06-21 | 山西纳安生物科技有限公司 | 一种基于牡丹籽油的祛斑面膜 |
CN110051573A (zh) * | 2019-04-12 | 2019-07-26 | 世堃堂(广东)生物科技有限公司 | 一种牡丹精华液 |
CN112675097A (zh) * | 2021-02-01 | 2021-04-20 | 厦门力嘉诚生物科技有限公司 | 一种含有石墨烯的牡丹精华原液面膜及其制备方法 |
-
2021
- 2021-07-26 CN CN202110841282.8A patent/CN113413345A/zh active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105560119A (zh) * | 2016-01-21 | 2016-05-11 | 定陶县地元生化制品有限公司 | 一种牡丹保湿液及其制备方法 |
CN106727127A (zh) * | 2016-12-20 | 2017-05-31 | 铜陵凤丹种植科技开发有限责任公司 | 一种含牡丹籽油的护肤精油及其制备方法 |
CN109481382A (zh) * | 2018-12-29 | 2019-03-19 | 株洲千金药业股份有限公司 | 一种含白花百合花水的保湿调理剂及其制备方法和面膜应用 |
CN110051573A (zh) * | 2019-04-12 | 2019-07-26 | 世堃堂(广东)生物科技有限公司 | 一种牡丹精华液 |
CN109908035A (zh) * | 2019-04-25 | 2019-06-21 | 山西纳安生物科技有限公司 | 一种基于牡丹籽油的祛斑面膜 |
CN112675097A (zh) * | 2021-02-01 | 2021-04-20 | 厦门力嘉诚生物科技有限公司 | 一种含有石墨烯的牡丹精华原液面膜及其制备方法 |
Non-Patent Citations (1)
Title |
---|
王昌涛等, 黑龙江科学技术出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115990130A (zh) * | 2023-03-25 | 2023-04-21 | 广州华厦生物制药有限公司 | 一种净颜瓷白雪肤面膜 |
CN115990130B (zh) * | 2023-03-25 | 2023-06-13 | 广州华厦生物制药有限公司 | 一种净颜瓷白雪肤面膜 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104173251B (zh) | 一种牦牛骨胶原肽美白面膜及其制备方法 | |
CN109464378B (zh) | 一种多效修护眼霜及其制备方法 | |
CN112494406A (zh) | 一种美白祛斑化妆品及其制备方法 | |
CN104666236A (zh) | 一种保湿护肤面膜 | |
CN110623882A (zh) | 一种美白祛斑面膜及其制备方法 | |
CN105687055A (zh) | 一种眼部修护精华液及其制备方法 | |
CN110755351A (zh) | 一种美白保湿修复组合物及其用途 | |
CN110279599B (zh) | 一种美白组合物、含美白组合物的套装及其制备方法 | |
CN110664644B (zh) | 一种含叶酸的护肤组合物、精华及其制备方法 | |
CN107334726A (zh) | 一种祛痘组合物及其制备方法和应用 | |
CN114306165B (zh) | 一种保湿组合物及其制备方法 | |
CN113384482B (zh) | 一种保湿嫩肤精华露及其制备方法 | |
CN114588061A (zh) | 一种抗衰除皱组合物及其制备方法和护肤品 | |
CN113413345A (zh) | 一种牡丹润颜滋养精华液及其制备方法 | |
CN113133967A (zh) | 一种牡丹精华液润肤面乳及其制备方法 | |
CN116509774A (zh) | 一种含青蒿提取物的去屑洗发制剂及其制备方法 | |
CN115737451A (zh) | 一种α-凝胶组合物、化妆品及其制备方法 | |
CN115778870A (zh) | 一种抗皱抗衰老的组合物及其制备方法和应用 | |
CN115414297A (zh) | 一种美白精华素及其制备方法 | |
CN115463048A (zh) | 一种祛痘焕颜精华液及其制备方法 | |
CN109662938B (zh) | 一种植物多糖保湿因子及其制备方法与应用 | |
CN112022766A (zh) | 一种美白祛痘组合物及其制备方法和应用 | |
CN108888573B (zh) | 舒敏保湿滋润霜及其制备方法 | |
CN111388377A (zh) | 一种烟酰胺原液及其制备方法 | |
CN112618422A (zh) | 复合美白组合物、制备方法及用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210921 |