CN113227147A - 全人源的抗cd30单链抗体及其应用 - Google Patents
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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Abstract
特异性结合CD30的新型抗体和抗体片段，尤其是全人源的单链抗体scFv。编码这些抗体的核酸、载体和表达所述核酸的宿主细胞,包含所述抗体的组合物、及其在治疗和诊断中的用途。
Description
PCT国内申请，说明书已公开。
Claims (27)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811582039 | 2018-12-24 | ||
| CN2018115820393 | 2018-12-24 | ||
| CN201911149363 | 2019-11-21 | ||
| CN2019111493630 | 2019-11-21 | ||
| PCT/CN2019/127947 WO2020135426A1 (zh) | 2018-12-24 | 2019-12-24 | 全人源的抗cd30单链抗体及其应用 |
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| CN113227147A true CN113227147A (zh) | 2021-08-06 |
| CN113227147B CN113227147B (zh) | 2022-07-19 |
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| CN (1) | CN113227147B (zh) |
| TW (1) | TWI741460B (zh) |
| WO (1) | WO2020135426A1 (zh) |
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| EP4225792A1 (en) | 2020-10-08 | 2023-08-16 | Affimed GmbH | Trispecific binders |
| WO2023007023A1 (en) | 2021-07-30 | 2023-02-02 | Affimed Gmbh | Duplexbodies |
| AR127568A1 (es) | 2021-11-03 | 2024-02-07 | Affimed Gmbh | Ligandos biespecíficos de cd16a |
| WO2024035341A1 (en) * | 2022-08-08 | 2024-02-15 | Tessa Therapeutics Ltd. | Cd30 antigen-binding molecules |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1638800A (zh) * | 2002-01-09 | 2005-07-13 | 米德列斯公司 | 抗cd30的人类单克隆抗体 |
| WO2007040653A2 (en) * | 2005-05-16 | 2007-04-12 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services National Institutes Of Health | Anti-cd30 antibodies that bind to intact cd30 but not soluble cd30 |
| WO2016008973A1 (en) * | 2014-07-16 | 2016-01-21 | Universitaet Zu Koeln | Chimeric antigen receptor and its use |
| CN106854245A (zh) * | 2016-12-28 | 2017-06-16 | 无锡傲锐东源生物科技有限公司 | 抗cd30蛋白单克隆抗体及其用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3431492B1 (en) * | 2012-04-27 | 2020-12-23 | Novo Nordisk A/S | Human cd30 ligand antigen binding proteins |
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- 2019-12-24 CN CN201980085704.4A patent/CN113227147B/zh active Active
- 2019-12-24 TW TW108147412A patent/TWI741460B/zh active
- 2019-12-24 WO PCT/CN2019/127947 patent/WO2020135426A1/zh active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1638800A (zh) * | 2002-01-09 | 2005-07-13 | 米德列斯公司 | 抗cd30的人类单克隆抗体 |
| WO2007040653A2 (en) * | 2005-05-16 | 2007-04-12 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services National Institutes Of Health | Anti-cd30 antibodies that bind to intact cd30 but not soluble cd30 |
| WO2016008973A1 (en) * | 2014-07-16 | 2016-01-21 | Universitaet Zu Koeln | Chimeric antigen receptor and its use |
| CN106854245A (zh) * | 2016-12-28 | 2017-06-16 | 无锡傲锐东源生物科技有限公司 | 抗cd30蛋白单克隆抗体及其用途 |
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| Publication number | Publication date |
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| CN113227147B (zh) | 2022-07-19 |
| WO2020135426A1 (zh) | 2020-07-02 |
| TW202024135A (zh) | 2020-07-01 |
| TWI741460B (zh) | 2021-10-01 |
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